Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYBV3G)

Drug Name
Paricalcitol Drug Info
Synonyms
Paracalcin; Zemplar; Abbott brand of paricalcitol; Paricalcitol [USAN]; Ab 122358; ABT-358; Zemplar (TN); Paricalcitol (USAN/INN); Paricalcitol, 19-nor-(OH)2-vitD2, paracalcin; (1R,3R)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]cyclohexane-1,3-diol; (1R,3R,7E)-17beta-[(2R,3E,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-9,10-secoestra-5,7-diene-1,3-diol; (1alpha.3beta,7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol; (7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1alpha,3beta,25-triol; 19-Nor-1,25-(OH)2D2; 19-Nor-1-alpha,25-dihydroxyvitamin D2; 19-Nor-1alpha,25-dihydroxyvitamin D2; 19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol,(1alpha,3beta,7E,22E)
Indication
Disease Entry ICD 11 Status REF
Hyperparathyroidism 5A51 Approved [1]
Therapeutic Class
Parasympathomimetics
Cross-matching ID
PubChem CID
5281104
ChEBI ID
CHEBI:7931
CAS Number
CAS 131918-61-1
TTD Drug ID
DMYBV3G
ACDINA Drug ID
D00509

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Vitamin D3 receptor (VDR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [8]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [9]
Calcidiol DMN4CV5 Hypophosphatemia Approved [8]
Doxercalciferol DM6FG1P Chronic kidney disease GB61 Approved [10]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [11]
Falecalcitrol DMBI9ZJ Hyperparathyroidism 5A51 Approved [12]
Dihydrotachysterol DMFB97P Hypocalcemia 5B5K.1 Approved [13]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [14]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [15]
S-06911 DMAYTIH Osteoporosis FB83.0 Phase 3 [16]
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Drug(s) Affected By Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [17]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [20]
Arsenic DMTL2Y1 N. A. N. A. Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [22]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [23]
Acetazolamide DM1AF5U Absence epilepsy Approved [3]
Ethanol DMDRQZU Chronic pain MG30 Approved [3]
Furosemide DMMQ8ZG Congestive heart failure BD10 Approved [3]
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Drug(s) Affected By Alkaline phosphatase, placental type (ALPP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [3]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [25]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [26]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [27]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Isoproterenol DMK7MEY Atrioventricular block Approved [28]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [29]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [30]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [31]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [32]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [33]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [34]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [35]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [36]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [36]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [37]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [38]
Capsaicin DMGMF6V Back pain ME84.Z Approved [39]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [40]
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Drug(s) Affected By Parathyroid hormone (PTH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [41]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [42]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [43]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [44]
Arsenic DMTL2Y1 N. A. N. A. Approved [21]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [45]
Phosphate DMUXQG7 Constipation DD91.1 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [3]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [3]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [47]
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Drug(s) Affected By Monocyte differentiation antigen CD14 (CD14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [48]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [49]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [52]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [53]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [54]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [56]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
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Drug(s) Affected By Integrin alpha-M (ITGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [61]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [62]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [63]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [65]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [66]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [67]
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Drug(s) Affected By Gastrin/cholecystokinin type B receptor (CCKBR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [70]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [71]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [68]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [23]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [68]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [71]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vitamin D3 receptor (VDR) TTK59TV VDR_HUMAN Agonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Drug Response [3]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [4]
Gastrin/cholecystokinin type B receptor (CCKBR) OTQSNXOI GASR_HUMAN Drug Response [3]
Integrin alpha-M (ITGAM) OTAG6HWU ITAM_HUMAN Gene/Protein Processing [5]
Monocyte differentiation antigen CD14 (CD14) OT83GJ47 CD14_HUMAN Gene/Protein Processing [5]
Parathyroid hormone (PTH) OTD721UF PTHY_HUMAN Gene/Protein Processing [6]
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R) OTQF5ZAK PTH1R_HUMAN Drug Response [3]
Vitamin D3 receptor OTFC7K35 VDR_HUMAN Protein Interaction/Cellular Processes [7]

References

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