Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM2NSK)

Drug Name
Adenosine Drug Info
Synonyms
Adenosine, homopolymer; Adenine 9-beta-D-arabinofuranoside; Adenine-9-beta-D-ribofuranoside; Beta-D-Ribofuranoside, adenine-9; EA6C60C2-6AFB-4264-A2F0-541373DB950E; (2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 4-Aminopyrazolo[3,4-d]pyrimidine ribonucleoside; 6-Amino-9-.beta.-ribofuranosyl-9H-purine; 6-Amino-9-beta-D-ribofuranosyl-9H-purine; 6-Amino-9beta-D-ribofuranosyl-9H-purine; 9-(beta-D-Arabinofuranosyl)adenine; 9-beta-D-Ribofuranosidoadenine; 9-beta-D-Ribofuranosyl-9H-purin-6-amine; 9-beta-D-Ribofuranosyladenine; 9beta-D-Ribofuranosyladenine
Indication
Disease Entry ICD 11 Status REF
Paroxysmal supraventricular tachycardia BC81.Z Approved [1]
Therapeutic Class
Antiarrhythmic Agents
Cross-matching ID
PubChem CID
60961
ChEBI ID
CHEBI:16335
CAS Number
CAS 5536-17-4
TTD Drug ID
DMM2NSK
VARIDT Drug ID
DR00904
INTEDE Drug ID
DR0046
ACDINA Drug ID
D00809

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Adenosine A2b receptor (ADORA2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [2]
A295 DM55GO2 Aggressive cancer 2A00-2F9Z IND submitted [12]
Tonapofylline DMBH316 Acute and chronic heart failure BD1Z Phase 2 [13]
YT-146 DM3YVKQ Hypertension BA00-BA04 Phase 2 [14]
AB928 DMDOXMN Metastatic colorectal cancer 2B91 Phase 1/2 [15]
KF-17837 DMQ6DLZ Parkinson disease 8A00.0 Phase 1 [16]
Xanthine DMFBOQ7 Apnea MD11.0 Phase 1 [17]
CVT-6883 DMY84TW Asthma CA23 Phase 1 [18]
PBF-1129 DMOPGXM Non-small-cell lung cancer 2C25.Y Phase 1 [15]
PF-1913539 DMXEU14 Alzheimer disease 8A20 Discontinued in Phase 3 [19]
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Drug(s) Transported By Multidrug resistance-associated protein 5 (ABCC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Folic Acid DMEMBJC Colorectal carcinoma Approved [20]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [21]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [22]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [23]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [24]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [25]
FLUORESCEIN DMQTFAO Ocular disease 1F00.1Z Approved [26]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [27]
[3H]cAMP DMZRQU7 Discovery agent N.A. Investigative [28]
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Drug(s) Transported By Equilibrative nucleoside transporter 1 (SLC29A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [30]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [31]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [32]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [33]
Clofarabine DMCVJ86 Acute lymphoblastic leukaemia 2A85 Approved [34]
Trifluridine DMG2YBD Herpetic keratitis 1F00.10 Approved [35]
Tecadenoson DM9T6MS Atrial fibrillation BC81.3 Discontinued in Phase 3 [36]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [48]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [53]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
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Drug(s) Metabolized By Sulfotransferase 1A1 (SULT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [37]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [38]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [40]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [41]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [42]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [43]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [44]
Epinephrine DM3KJBC Acute asthma CA23 Approved [45]
Benzyl alcohol DMBVYDI Head and body lice 1G00.0 Approved [46]
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Drug(s) Metabolized By Adenosine aminohydrolase (ADA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nelarabine DMB6VEG leukaemia 2A60-2B33 Approved [47]
Drug(s) Affected By L-lactate dehydrogenase A chain (LDHA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
Etretinate DM2CZFA Keratosis ED56 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [60]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [62]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [65]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [66]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [69]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [71]
Gefitinib DM15F0X Colon adenocarcinoma Approved [72]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [73]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
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Drug(s) Affected By Dipeptidyl peptidase 4 (DPP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Saxagliptin DMGXENV Type-2 diabetes 5A11 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Testosterone DM7HUNW Hot flushes GA30 Approved [77]
Alogliptin DM8WI3R Type-2 diabetes 5A11 Approved [78]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [81]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [82]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [83]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [66]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [84]
Paclitaxel DMLB81S Breast carcinoma Approved [85]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [65]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [87]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [88]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [69]
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Drug(s) Affected By Toll-like receptor 4 (TLR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [90]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [95]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [97]
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Drug(s) Affected By CASP8 and FADD-like apoptosis regulator (CFLAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Methotrexate DM2TEOL Anterior urethra cancer Approved [100]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [101]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [105]
Ethacrynic acid DM60QMR Edema MG29 Approved [106]
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Drug(s) Affected By Dickkopf-related protein 1 (DKK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Quercetin DM3NC4M Obesity 5B81 Approved [108]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [109]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [113]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [114]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [115]
Gefitinib DM15F0X Colon adenocarcinoma Approved [116]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [117]
Selenium DM25CGV N. A. N. A. Approved [118]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [119]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
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Drug(s) Affected By Pro-epidermal growth factor (EGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [126]
Testosterone DM7HUNW Hot flushes GA30 Approved [77]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
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Drug(s) Affected By Protransforming growth factor alpha (TGFA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [129]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [130]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [132]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [133]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [87]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [136]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [137]
Prednisone DM2HG4X Acute asthma CA23 Approved [138]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [139]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
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Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [141]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [142]
Gefitinib DM15F0X Colon adenocarcinoma Approved [143]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [144]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [145]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [146]
Quercetin DM3NC4M Obesity 5B81 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [144]
Estrone DM5T6US Acne vulgaris ED80 Approved [149]
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Drug(s) Affected By Insulin-like growth factor I (IGF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dantrolene DM1D8XY Hyperthermia MG26 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [151]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [155]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Testosterone DM7HUNW Hot flushes GA30 Approved [156]
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Drug(s) Affected By Monocyte differentiation antigen CD14 (CD14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [114]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [157]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [158]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [160]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [161]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [162]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
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Drug(s) Affected By Adenosine receptor A3 (ADORA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [165]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [167]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
Indomethacin DMSC4A7 Bursitis Approved [169]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [170]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [171]
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Drug(s) Affected By Bone morphogenetic protein 2 (BMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [172]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [177]
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Drug(s) Affected By Bone morphogenetic protein 4 (BMP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [178]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [181]
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Drug(s) Affected By Cystic fibrosis transmembrane conductance regulator (CFTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [182]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [184]
Quercetin DM3NC4M Obesity 5B81 Approved [185]
Miglustat DM5J64S Niemann-Pick disease type C Approved [186]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [187]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [184]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [188]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [188]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
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Drug(s) Affected By Cyclic AMP-responsive element-binding protein 1 (CREB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [189]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Selenium DM25CGV N. A. N. A. Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [192]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [194]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [195]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [196]
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Drug(s) Affected By Ribosomal protein S6 kinase beta-1 (RPS6KB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [197]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [198]
Gefitinib DM15F0X Colon adenocarcinoma Approved [199]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [200]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [201]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [202]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [165]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [204]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [205]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [207]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [142]
Gefitinib DM15F0X Colon adenocarcinoma Approved [208]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [209]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [210]
Selenium DM25CGV N. A. N. A. Approved [191]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [119]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [211]
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Drug(s) Affected By Adenosine receptor A2a (ADORA2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [212]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [213]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [214]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [215]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [214]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [214]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenosine receptor A1 (ADORA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Gefitinib DM15F0X Colon adenocarcinoma Approved [217]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [218]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [219]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [220]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [222]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [223]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [226]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [227]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [228]
Testosterone DM7HUNW Hot flushes GA30 Approved [229]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [230]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [231]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Selenium DM25CGV N. A. N. A. Approved [191]
Quercetin DM3NC4M Obesity 5B81 Approved [233]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [235]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [236]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [237]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [238]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bone morphogenetic protein receptor type-1A (BMPR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Arsenic DMTL2Y1 N. A. N. A. Approved [240]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [241]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [242]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glial cell line-derived neurotrophic factor (GDNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [243]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [244]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [245]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [246]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [247]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [248]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [249]
cordycepin DM72Y01 Discovery agent N.A. Investigative [11]
paraquat DMR8O3X Discovery agent N.A. Investigative [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [251]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [198]
Gefitinib DM15F0X Colon adenocarcinoma Approved [199]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [252]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [119]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [253]
Quercetin DM3NC4M Obesity 5B81 Approved [254]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [255]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [257]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [258]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [259]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [260]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [261]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [262]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [263]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [264]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [265]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [266]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proliferation marker protein Ki-67 (MKI67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [267]
Methotrexate DM2TEOL Anterior urethra cancer Approved [268]
Quercetin DM3NC4M Obesity 5B81 Approved [233]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [158]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [270]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [271]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [272]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [273]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [274]
Gefitinib DM15F0X Colon adenocarcinoma Approved [275]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
Epinephrine DM3KJBC Acute asthma CA23 Approved [277]
Quercetin DM3NC4M Obesity 5B81 Approved [278]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [279]
Fructose DM43AN2 Vomiting MD90 Approved [280]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [281]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [282]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Placenta growth factor (PGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [132]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [283]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [284]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [285]
Urethane DM7NSI0 N. A. N. A. Phase 4 [286]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [287]
Gefitinib DM15F0X Colon adenocarcinoma Approved [288]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [289]
Selenium DM25CGV N. A. N. A. Approved [191]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [290]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [291]
Quercetin DM3NC4M Obesity 5B81 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [292]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [213]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [294]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [295]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [178]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [296]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [297]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [298]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Meloxicam DM2AR7L Arthritis FA20 Approved [300]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [301]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [302]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transforming growth factor beta-2 proprotein (TGFB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [303]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [157]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [304]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [305]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [306]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [231]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [307]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [308]
Ethacrynic acid DM60QMR Edema MG29 Approved [309]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [160]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [310]
Testosterone DM7HUNW Hot flushes GA30 Approved [311]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Menthol DMG2KW7 Back pain ME84.Z Approved [312]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [313]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [266]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [178]
Verapamil DMA7PEW Angina pectoris BA40 Approved [314]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [98]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [297]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [209]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
Meloxicam DM2AR7L Arthritis FA20 Approved [315]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [316]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [317]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [318]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Selenium DM25CGV N. A. N. A. Approved [191]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [319]
Methotrexate DM2TEOL Anterior urethra cancer Approved [320]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [321]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [279]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FAS-associated death domain protein (FADD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [178]
Selenium DM25CGV N. A. N. A. Approved [322]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [323]
Quercetin DM3NC4M Obesity 5B81 Approved [298]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [157]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [324]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [325]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [326]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [327]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Frizzled-5 (FZD5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Ethacrynic acid DM60QMR Edema MG29 Approved [329]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [160]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [330]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [266]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [274]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Methotrexate DM2TEOL Anterior urethra cancer Approved [320]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [157]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [331]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [332]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [333]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [330]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [266]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [334]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [335]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [336]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [337]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [333]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [338]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [339]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [341]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [342]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [88]
Gefitinib DM15F0X Colon adenocarcinoma Approved [275]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [343]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Selenium DM25CGV N. A. N. A. Approved [191]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [301]
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [344]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Prednisone DM2HG4X Acute asthma CA23 Approved [346]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [346]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [347]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [348]
Epinephrine DM3KJBC Acute asthma CA23 Approved [349]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Fluoxetine DM3PD2C Bipolar depression Approved [350]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Estrogen receptor beta (ESR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Gefitinib DM15F0X Colon adenocarcinoma Approved [351]
Quercetin DM3NC4M Obesity 5B81 Approved [352]
Estrone DM5T6US Acne vulgaris ED80 Approved [353]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [354]
Testosterone DM7HUNW Hot flushes GA30 Approved [355]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [356]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [357]
Mestranol DMG3F94 Contraception QA21 Approved [358]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [359]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Frizzled-3 (FZD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [360]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [132]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [361]
Arsenic DMTL2Y1 N. A. N. A. Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diablo IAP-binding mitochondrial protein (DIABLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [362]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [363]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [364]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [365]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [366]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [368]
Fructose DM43AN2 Vomiting MD90 Approved [369]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [370]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [371]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [59]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [372]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [373]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [373]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lymphoid enhancer-binding factor 1 (LEF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethacrynic acid DM60QMR Edema MG29 Approved [329]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [228]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [306]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [374]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [375]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [221]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [376]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [377]
Thymoquinone DMVDTR2 Polycystic ovarian syndrome 5A80.1 Phase 2/3 [378]
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Drug(s) Affected By Lymphocyte antigen 96 (LY96)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [88]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [379]
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [380]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [381]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [382]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 11 (MAPK11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [320]
Quercetin DM3NC4M Obesity 5B81 Approved [383]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [384]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [385]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [233]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [213]
Leflunomide DMR8ONJ Arthritis FA20 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [386]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/nucleoside cotransporter 2 (SLC28A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Uridine DMQTREB Depression 6A70-6A7Z Approved [387]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [388]
Arsenic DMTL2Y1 N. A. N. A. Approved [240]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [389]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [367]
AMG 386 DMQJXL4 Breast cancer 2C60-2C65 Phase 3 [387]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [390]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [391]
Purine Riboside DMHNS0V Discovery agent N.A. Investigative [387]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Equilibrative nucleoside transporter 3 (SLC29A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [285]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [392]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [392]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Purine nucleoside phosphorylase (PNP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [393]
Panobinostat DM58WKG Chronic graft versus host disease Approved [55]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [394]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [395]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [396]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Equilibrative nucleoside transporter 2 (SLC29A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [397]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [397]
Arsenic DMTL2Y1 N. A. N. A. Approved [240]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [389]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [221]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [398]
Uridine DMQTREB Depression 6A70-6A7Z Approved [399]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [400]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/nucleoside cotransporter 1 (SLC28A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Uridine DMQTREB Depression 6A70-6A7Z Approved [401]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [380]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [402]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [403]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [404]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [404]
DEOXYCYTIDINE DMYE5LJ Acute myeloid leukaemia 2A60 Approved [401]
Urethane DM7NSI0 N. A. N. A. Phase 4 [286]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosine A2b receptor (ADORA2B) TTNE7KG AA2BR_HUMAN Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Equilibrative nucleoside transporter 1 (SLC29A1) DTXD1TQ S29A1_HUMAN Substrate [3]
Multidrug resistance-associated protein 5 (ABCC5) DTYVM24 MRP5_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Substrate [5]
Adenosine aminohydrolase (ADA) DEDQHBV ADA_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Adenosine receptor A1 (ADORA1) OTI7X39E AA1R_HUMAN Protein Interaction/Cellular Processes [7]
Adenosine receptor A2a (ADORA2A) OTVRBZ0I AA2AR_HUMAN Protein Interaction/Cellular Processes [7]
Adenosine receptor A3 (ADORA3) OTHO1BLK AA3R_HUMAN Gene/Protein Processing [8]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Protein Interaction/Cellular Processes [9]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [10]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [10]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [10]
Bone morphogenetic protein 2 (BMP2) OT23T37S BMP2_HUMAN Gene/Protein Processing [11]
Bone morphogenetic protein 4 (BMP4) OTPZMDFH BMP4_HUMAN Gene/Protein Processing [11]
Bone morphogenetic protein receptor type-1A (BMPR1A) OTQOA4ZH BMR1A_HUMAN Gene/Protein Processing [11]

References

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