General Information of Drug Combination (ID: DCTARHH)

Drug Combination Name
Romidepsin Methotrexate
Indication
Disease Entry Status REF
Adult T acute lymphoblastic leukemia Investigative [1]
Component Drugs Romidepsin   DMT5GNL Methotrexate   DM2TEOL
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL is unavailable
High-throughput Screening Result Testing Cell Line: MOLT-4
Zero Interaction Potency (ZIP) Score: 0.51
Bliss Independence Score: 1.45
Loewe Additivity Score: 0.9
LHighest Single Agent (HSA) Score: 1.45

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Romidepsin
Disease Entry ICD 11 Status REF
Cutaneous T-cell lymphoma 2B01 Approved [2]
Gastrin-producing neuroendocrine tumor N.A. Approved [3]
Glucagonoma N.A. Approved [3]
Insulinoma 2C10.1 Approved [3]
Lung carcinoid tumor N.A. Approved [3]
Melanoma 2C30 Approved [3]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified N.A. Approved [3]
Primary cutaneous T-cell lymphoma N.A. Approved [3]
Urethral cancer 2C93 Approved [3]
Peripheral T-cell lymphoma 2A90.C Phase 3 [4]
Renal cell carcinoma 2C90 Phase 3 [2]
Romidepsin Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [14]
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Romidepsin Interacts with 2 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [15]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [15]
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Romidepsin Interacts with 3 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [16]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Metabolism [17]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Metabolism [18]
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Romidepsin Interacts with 41 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [19]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Affects Expression [20]
E3 SUMO-protein ligase CBX4 (CBX4) OT4XVRRF CBX4_HUMAN Increases Expression [21]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [22]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Expression [23]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Increases Expression [24]
Serine/threonine-protein kinase 17B (STK17B) OT4NYNO8 ST17B_HUMAN Increases Expression [21]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Decreases Expression [25]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Expression [25]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Decreases Expression [25]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Decreases Phosphorylation [25]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [26]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Increases Expression [21]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Decreases Expression [25]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Phosphorylation [13]
Transcription factor JunD (JUND) OTNKACJD JUND_HUMAN Increases Expression [21]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Increases Expression [26]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [25]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Expression [26]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Phosphorylation [13]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Phosphorylation [13]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Increases Phosphorylation [27]
Receptor-type tyrosine-protein kinase FLT3 (FLT3) OTMSRYMK FLT3_HUMAN Decreases Phosphorylation [13]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Increases Expression [21]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [28]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Activity [25]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Cleavage [26]
Friend leukemia integration 1 transcription factor (FLI1) OT0EV3LX FLI1_HUMAN Decreases Expression [29]
RNA-binding protein EWS (EWSR1) OT7SRHV3 EWS_HUMAN Decreases Expression [29]
DNA repair protein RAD51 homolog 1 (RAD51) OTNVWGC1 RAD51_HUMAN Decreases Expression [13]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Increases Expression [27]
Bcl-2-interacting killer (BIK) OTTH1T3D BIK_HUMAN Increases Expression [21]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) OT6VY3A3 SPTN1_HUMAN Increases Expression [21]
Nuclear receptor subfamily 1 group I member 3 (NR1I3) OTS3SGH7 NR1I3_HUMAN Increases Expression [30]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [27]
Histone H3.1t (H3-4) OTY6ITYF H31T_HUMAN Increases Acetylation [30]
Sodium/iodide cotransporter (SLC5A5) OTU7E9G7 SC5A5_HUMAN Increases Expression [31]
Mitogen-activated protein kinase kinase kinase 3 (MAP3K3) OT53LJGW M3K3_HUMAN Increases Expression [21]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Affects Metabolism [32]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Decreases Response To Substance [33]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Decreases Response To Substance [26]
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⏷ Show the Full List of 41 DOT(s)
Indication(s) of Methotrexate
Disease Entry ICD 11 Status REF
Anterior urethra cancer N.A. Approved [5]
Burkitt lymphoma N.A. Approved [5]
Childhood acute lymphoblastic leukemia N.A. Approved [5]
Choriocarcinoma 2C75.0 Approved [6]
Gestational trophoblastic neoplasia 2F33-2F76 Approved [5]
Head and neck cancer 2D42 Approved [5]
Inflammation 1A00-CA43.1 Approved [5]
leukaemia 2A60-2B33 Approved [7]
Leukemia N.A. Approved [5]
Lung cancer 2C25.0 Approved [5]
Mycosis fungoides 2B01 Approved [5]
Posterior urethra cancer N.A. Approved [5]
Psoriasis EA90 Approved [5]
Sensorineural hearing loss disorder N.A. Approved [5]
Urticaria EB00-EB05 Approved [5]
Proliferative vitreoretinopathy 9B78.2 Phase 3 [8]
Solid tumour/cancer 2A00-2F9Z Phase 3 [7]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1/2 [9]
Rheumatoid arthritis FA20 Phase 1 [10]
Prostate cancer 2C82.0 Investigative [11]
Methotrexate Interacts with 2 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Proton-coupled folate transporter (SLC46A1) TTY8Z2E PCFT_HUMAN Modulator [52]
Solute carrier family 19 member 1 (SLC19A1) TT09I7D S19A1_HUMAN Modulator [53]
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Methotrexate Interacts with 17 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [54]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [55]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [56]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [57]
Organic anion transporter 2 (SLC22A7) DT0OC1Q S22A7_HUMAN Substrate [58]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [59]
Multidrug resistance-associated protein 3 (ABCC3) DTQ3ZHF MRP3_HUMAN Substrate [60]
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [61]
Multidrug resistance-associated protein 5 (ABCC5) DTYVM24 MRP5_HUMAN Substrate [62]
Organic anion transporter 1 (SLC22A6) DTQ23VB S22A6_HUMAN Substrate [63]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [64]
Organic anion transporter 4 (SLC22A11) DT06JWZ S22AB_HUMAN Substrate [65]
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTE2B1D SO1A2_HUMAN Substrate [66]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [67]
Multidrug resistance-associated protein 8 (ABCC11) DTWN7FC ABCCB_HUMAN Substrate [68]
Folate transporter 1 (SLC19A1) DTOSN46 S19A1_HUMAN Substrate [69]
Proton-coupled folate transporter (SLC46A1) DTDJEMI PCFT_HUMAN Substrate [70]
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⏷ Show the Full List of 17 DTP(s)
Methotrexate Interacts with 7 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Thiopurine methyltransferase (TPMT) DEFQ8VO TPMT_HUMAN Metabolism [71]
Methylenetetrahydrofolate reductase (MTHFR) DEOXTPZ MTHR_HUMAN Metabolism [72]
Thymidylate synthase (TYMS) DEASG0Q TYSY_HUMAN Metabolism [72]
Dihydrofolate reductase (DHFR) DE4EGMZ DYR_HUMAN Metabolism [72]
Gamma-Glu-X carboxypeptidase (GGH) DEU7MWJ GGH_HUMAN Metabolism [72]
Folylpolyglutamate synthase (FPGS) DECWT2V FOLC_HUMAN Metabolism [72]
Glutamate carboxypeptidase II (FOLH1) DEN8V7Z FOLH1_HUMAN Metabolism [73]
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⏷ Show the Full List of 7 DME(s)
Methotrexate Interacts with 1626 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Thiopurine S-methyltransferase (TPMT) OTFOX70W TPMT_HUMAN Decreases Expression [39]
Gamma-glutamyl hydrolase (GGH) OTL71J7T GGH_HUMAN Decreases Expression [74]
Dihydrofolate reductase (DHFR) OT3DVIGM DYR_HUMAN Decreases Response To Substance [75]
Solute carrier family 22 member 7 (SLC22A7) OTKTNH1W S22A7_HUMAN Increases Expression [39]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Decreases Expression [74]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Increases Expression [74]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Increases Expression [41]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Decreases Expression [74]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [76]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Decreases Expression [74]
Solute carrier organic anion transporter family member 1B1 (SLCO1B1) OTNEN8QK SO1B1_HUMAN Increases Response To Substance [77]
Proton-coupled folate transporter (SLC46A1) OT049V7Y PCFT_HUMAN Increases Response To Substance [77]
Reduced folate transporter (SLC19A1) OTWB0BTO S19A1_HUMAN Decreases Response To Substance [78]
Solute carrier family 22 member 6 (SLC22A6) OTKRCBVM S22A6_HUMAN Increases Response To Substance [79]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Affects Response To Substance [80]
Organic anion transporter 3 (SLC22A8) OT8BY933 S22A8_HUMAN Increases Response To Substance [79]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Decreases Expression [35]
Sulfotransferase 1E1 (SULT1E1) OTGPJ517 ST1E1_HUMAN Increases Expression [81]
Sulfotransferase 1A1 (SULT1A1) OT0K7JIE ST1A1_HUMAN Increases Expression [81]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Decreases Activity [82]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Decreases Expression [83]
TANK-binding kinase 1-binding protein 1 (TBKBP1) OTXTU37H TBKB1_HUMAN Decreases Expression [35]
Alternative prion protein (PRNP) OTE85L1Q APRIO_HUMAN Decreases Expression [35]
AH receptor-interacting protein (AIP) OTDJ3OSV AIP_HUMAN Increases Expression [35]
Toll-like receptor 4 (TLR4) OTP7ML3S TLR4_HUMAN Decreases Expression [35]
C-C motif chemokine 21 (CCL21) OT7DOXEM CCL21_HUMAN Decreases Expression [35]
Peroxisomal targeting signal 2 receptor (PEX7) OTM7VBRC PEX7_HUMAN Increases Expression [35]
Acetyl-CoA carboxylase 2 (ACACB) OT96UIP1 ACACB_HUMAN Increases Expression [35]
Stearoyl-CoA desaturase (SCD) OTB1073G SCD_HUMAN Increases Expression [35]
AP-3 complex subunit delta-1 (AP3D1) OTJLI0IM AP3D1_HUMAN Decreases Expression [35]
C-X-C motif chemokine 11 (CXCL11) OT353XE3 CXL11_HUMAN Decreases Expression [35]
Syntaxin-16 (STX16) OTM7TAOE STX16_HUMAN Increases Expression [35]
Phytanoyl-CoA dioxygenase, peroxisomal (PHYH) OTUG4BWA PAHX_HUMAN Increases Expression [35]
Long-chain fatty acid transport protein 2 (SLC27A2) OT7JEG5F S27A2_HUMAN Increases Expression [35]
Synaptojanin-2 (SYNJ2) OTLRHXP1 SYNJ2_HUMAN Increases Expression [35]
FYN-binding protein 1 (FYB1) OT6345CH FYB1_HUMAN Decreases Expression [35]
Phospholipid scramblase 1 (PLSCR1) OTGY9B5T PLS1_HUMAN Decreases Expression [35]
C-C motif chemokine 25 (CCL25) OTLWJ8CJ CCL25_HUMAN Decreases Expression [35]
DNA-directed RNA polymerase I subunit RPA34 (POLR1G) OTEGR9C2 RPA34_HUMAN Decreases Expression [35]
Plexin-B1 (PLXNB1) OTCA7JIT PLXB1_HUMAN Increases Expression [35]
Hypocretin neuropeptide precursor (HCRT) OTQ4FGI9 OREX_HUMAN Decreases Expression [35]
Transcription factor 21 (TCF21) OT393IMA TCF21_HUMAN Decreases Expression [35]
Acyl-CoA (FADS1) OTUYOYHX FADS1_HUMAN Increases Expression [35]
Long-chain-fatty-acid--CoA ligase 4 (ACSL4) OTI71MUJ ACSL4_HUMAN Increases Expression [35]
Target of Myb1 membrane trafficking protein (TOM1) OT30QA56 TOM1_HUMAN Decreases Expression [35]
Receptor activity-modifying protein 1 (RAMP1) OT7UT2XB RAMP1_HUMAN Decreases Expression [35]
Receptor activity-modifying protein 2 (RAMP2) OTGQXLH5 RAMP2_HUMAN Decreases Expression [35]
Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B) OTSLSPZG FCG3B_HUMAN Decreases Expression [35]
ICOS ligand (ICOSLG) OTAD976B ICOSL_HUMAN Decreases Expression [35]
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) OTMVHF9E LGR5_HUMAN Decreases Expression [35]
Protein XRP2 (RP2) OTK050I3 XRP2_HUMAN Increases Expression [35]
Diacylglycerol O-acyltransferase 1 (DGAT1) OTL104WL DGAT1_HUMAN Increases Expression [35]
DnaJ homolog subfamily B member 5 (DNAJB5) OT7WDJ5C DNJB5_HUMAN Decreases Expression [35]
Cystatin-F (CST7) OTQWZUVQ CYTF_HUMAN Decreases Expression [35]
SUN domain-containing protein 1 (SUN1) OTIU8V4U SUN1_HUMAN Increases Expression [35]
Nuclear factor of activated T-cells 5 (NFAT5) OTKIE59S NFAT5_HUMAN Increases Expression [35]
Interleukin-18 receptor accessory protein (IL18RAP) OTCUB1EV I18RA_HUMAN Decreases Expression [35]
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) OT1G9297 TFIP8_HUMAN Decreases Expression [35]
Fibroblast growth factor 19 (FGF19) OT2DVJWY FGF19_HUMAN Decreases Expression [35]
Putative lipid scramblase CLPTM1 (CLPTM1) OT14QP7N CLPT1_HUMAN Decreases Expression [35]
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) OTZDQ29F TOM40_HUMAN Increases Expression [35]
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1) OTOEEEXG HPRT_HUMAN Decreases Expression [35]
Prothrombin (F2) OTNFSM49 THRB_HUMAN Increases Expression [35]
Complement C3 (C3) OTCH5GS0 CO3_HUMAN Increases Expression [35]
Complement C5 (C5) OTSL3OIC CO5_HUMAN Increases Expression [35]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [35]
Platelet-derived growth factor subunit B (PDGFB) OTMFMFC3 PDGFB_HUMAN Decreases Expression [35]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Decreases Expression [35]
Beta-nerve growth factor (NGF) OTOLABJT NGF_HUMAN Increases Expression [35]
Prolactin (PRL) OTWFQGX7 PRL_HUMAN Decreases Expression [35]
Insulin (INS) OTZ85PDU INS_HUMAN Decreases Expression [35]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Decreases Expression [35]
Interleukin-1 alpha (IL1A) OTPSGILV IL1A_HUMAN Decreases Expression [35]
HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) OT7KZMP2 DRA_HUMAN Decreases Expression [35]
Myelin basic protein (MBP) OTFZCEDB MBP_HUMAN Increases Expression [35]
Complement C1q subcomponent subunit B (C1QB) OT2G1IOX C1QB_HUMAN Decreases Expression [35]
Fibronectin (FN1) OTB5ZN4Q FINC_HUMAN Increases Expression [35]
Platelet factor 4 (PF4) OTEMJU68 PLF4_HUMAN Decreases Expression [35]
Plasma kallikrein (KLKB1) OTGSEISX KLKB1_HUMAN Increases Expression [35]
Catalase (CAT) OTHEBX9R CATA_HUMAN Increases Expression [35]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Decreases Expression [35]
Amyloid-beta precursor protein (APP) OTKFD7R4 A4_HUMAN Decreases Expression [35]
Interleukin-4 (IL4) OTOXBWAU IL4_HUMAN Decreases Expression [35]
Insulin receptor (INSR) OTTY341H INSR_HUMAN Increases Expression [35]
Protein S100-A9 (S100A9) OTOARHCS S10A9_HUMAN Decreases Expression [35]
T-cell surface antigen CD2 (CD2) OTLYO0DB CD2_HUMAN Decreases Expression [35]
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) OTREV92I CEAM5_HUMAN Increases Expression [35]
Fatty acid-binding protein, liver (FABP1) OTR34ETM FABPL_HUMAN Increases Expression [35]
Vitamin K-dependent protein S (PROS1) OTXQWNOI PROS_HUMAN Increases Expression [35]
Macrophage colony-stimulating factor 1 receptor (CSF1R) OTDYTB9C CSF1R_HUMAN Decreases Expression [35]
Complement component C8 alpha chain (C8A) OTIJ65J4 CO8A_HUMAN Increases Expression [35]
Pulmonary surfactant-associated protein B (SFTPB) OTOHS07E PSPB_HUMAN Decreases Expression [35]
Thrombospondin-1 (THBS1) OT0ECWK3 TSP1_HUMAN Decreases Expression [35]
Cathepsin G (CTSG) OT85ZMQG CATG_HUMAN Decreases Expression [35]
Receptor-type tyrosine-protein phosphatase C (PTPRC) OT6KOR77 PTPRC_HUMAN Decreases Expression [35]
Integrin alpha-5 (ITGA5) OT3RCI67 ITA5_HUMAN Increases Expression [35]
Interleukin-3 (IL3) OT0CQ35N IL3_HUMAN Decreases Expression [35]
Glutathione S-transferase A2 (GSTA2) OTW7UB1H GSTA2_HUMAN Increases Expression [35]
CD48 antigen (CD48) OT83ZNPP CD48_HUMAN Decreases Expression [35]
Macrophage colony-stimulating factor 1 (CSF1) OT68M7RD CSF1_HUMAN Decreases Expression [35]
Heat shock 70 kDa protein 1A (HSPA1A) OTKGIE76 HS71A_HUMAN Decreases Expression [35]
C-C motif chemokine 3 (CCL3) OTW2H3ND CCL3_HUMAN Decreases Expression [35]
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) OT9LBJVN ODP2_HUMAN Increases Expression [35]
T-cell-specific surface glycoprotein CD28 (CD28) OTT5XJST CD28_HUMAN Decreases Expression [35]
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) OTA4P0FC ACADM_HUMAN Increases Expression [35]
Steroid hormone receptor ERR1 (ESRRA) OTTDTUSP ERR1_HUMAN Decreases Expression [35]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Increases Expression [35]
Cytochrome c oxidase subunit 6A1, mitochondrial (COX6A1) OT77MV8G CX6A1_HUMAN Decreases Expression [35]
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) OTPG0K7E IMDH2_HUMAN Decreases Expression [35]
Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A) OT0OUDUT FCG2A_HUMAN Increases Expression [35]
Granzyme A (GZMA) OT43R33L GRAA_HUMAN Decreases Expression [35]
Proto-oncogene tyrosine-protein kinase Src (SRC) OTETYX40 SRC_HUMAN Decreases Expression [35]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Decreases Expression [35]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Decreases Expression [35]
L-selectin (SELL) OT6RAJZR LYAM1_HUMAN Decreases Expression [35]
Phospholipase A2, membrane associated (PLA2G2A) OT1NY7BF PA2GA_HUMAN Increases Expression [35]
Interleukin-2 receptor subunit beta (IL2RB) OT6M0F70 IL2RB_HUMAN Decreases Expression [35]
Cytochrome c oxidase subunit 6B1 (COX6B1) OTNKXYQI CX6B1_HUMAN Decreases Expression [35]
B-lymphocyte antigen CD19 (CD19) OTCPF9NF CD19_HUMAN Decreases Expression [35]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Increases Expression [35]
Antigen-presenting glycoprotein CD1d (CD1D) OT3ROU4J CD1D_HUMAN Increases Expression [35]
SH2/SH3 adapter protein NCK1 (NCK1) OTKYZ4OP NCK1_HUMAN Decreases Expression [35]
C-C motif chemokine 3-like 1 (CCL3L1) OTQXCYB1 CL3L1_HUMAN Decreases Expression [35]
HLA class I histocompatibility antigen, alpha chain G (HLA-G) OTMLK1KN HLAG_HUMAN Decreases Expression [35]
Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12) OTFL5KR5 LOX12_HUMAN Decreases Expression [35]
Lipopolysaccharide-binding protein (LBP) OTQXAH4L LBP_HUMAN Increases Expression [35]
Lymphocyte function-associated antigen 3 (CD58) OTIUGMGS LFA3_HUMAN Increases Expression [35]
Spermidine synthase (SRM) OT4N5MDP SPEE_HUMAN Decreases Expression [35]
L-serine dehydratase/L-threonine deaminase (SDS) OT5WTJ2M SDHL_HUMAN Increases Expression [35]
Integrin alpha-L (ITGAL) OTCUQAIS ITAL_HUMAN Increases Expression [35]
Mimecan (OGN) OTKP5S4L MIME_HUMAN Decreases Expression [35]
Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1) OT6QGM5Y IMDH1_HUMAN Decreases Expression [35]
T-cell surface glycoprotein CD3 zeta chain (CD247) OT45FGUX CD3Z_HUMAN Decreases Expression [35]
fMet-Leu-Phe receptor (FPR1) OTFF9I6W FPR1_HUMAN Decreases Expression [35]
Kit ligand (KITLG) OTB9AVQ4 SCF_HUMAN Decreases Expression [35]
C5a anaphylatoxin chemotactic receptor 1 (C5AR1) OT58QDI9 C5AR1_HUMAN Decreases Expression [35]
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) OTOCBX7P TNFL4_HUMAN Increases Expression [35]
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3) OTGP7D5Y GATA3_HUMAN Increases Expression [35]
Interleukin-32 (IL32) OT3FHZ81 IL32_HUMAN Decreases Expression [35]
Myeloblastin (PRTN3) OT72MHP7 PRTN3_HUMAN Decreases Expression [35]
Tenascin (TNC) OTK4FSHR TENA_HUMAN Increases Expression [35]
Deoxyribonuclease-1 (DNASE1) OTM4KWB3 DNAS1_HUMAN Increases Expression [35]
C-X-C chemokine receptor type 2 (CXCR2) OTISGW7L CXCR2_HUMAN Decreases Expression [35]
N-formyl peptide receptor 2 (FPR2) OTEZ2THZ FPR2_HUMAN Decreases Expression [35]
Cathepsin S (CTSS) OT3PXIPM CATS_HUMAN Decreases Expression [35]
Interleukin-1 receptor type 2 (IL1R2) OT0G7E35 IL1R2_HUMAN Decreases Expression [35]
ATP-binding cassette sub-family D member 3 (ABCD3) OT2PITLX ABCD3_HUMAN Increases Expression [35]
T-cell surface glycoprotein CD1b (CD1B) OT4D5EG7 CD1B_HUMAN Decreases Expression [35]
Enoyl-CoA hydratase, mitochondrial (ECHS1) OTS0593S ECHM_HUMAN Increases Expression [35]
High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) OTBZBL9Y FCERG_HUMAN Decreases Expression [35]
Coronin-1A (CORO1A) OTVAZOHC COR1A_HUMAN Decreases Expression [35]
Protein S100-A11 (S100A11) OTI57KDN S10AB_HUMAN Decreases Expression [35]
Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) OTCJD51H FCG2B_HUMAN Decreases Expression [35]
G-protein coupled receptor 183 (GPR183) OTRILX7G GP183_HUMAN Decreases Expression [35]
ETS-related transcription factor Elf-1 (ELF1) OTV5LKIA ELF1_HUMAN Decreases Expression [35]
Lymphocyte-specific protein 1 (LSP1) OTSPSIFO LSP1_HUMAN Increases Expression [35]
ATP-binding cassette sub-family D member 1 (ABCD1) OT3FL9W0 ABCD1_HUMAN Decreases Expression [35]
Heat shock 70 kDa protein 4 (HSPA4) OT5HR0AR HSP74_HUMAN Increases Expression [35]
Gap junction alpha-4 protein (GJA4) OTUPCT1V CXA4_HUMAN Decreases Expression [35]
Pro-adrenomedullin (ADM) OT7T0TA4 ADML_HUMAN Decreases Expression [35]
Histamine H1 receptor (HRH1) OT8F9FV6 HRH1_HUMAN Increases Expression [35]
Phosphoenolpyruvate carboxykinase, cytosolic (PCK1) OTNWEJ5Y PCKGC_HUMAN Increases Expression [35]
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) OTZG1W8W CEAM3_HUMAN Decreases Expression [35]
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) OTQOUHVK CEAM6_HUMAN Increases Expression [35]
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) OTO557N2 ECHA_HUMAN Increases Expression [35]
Kappa-type opioid receptor (OPRK1) OTXCZF4L OPRK_HUMAN Increases Expression [35]
Regulator of G-protein signaling 2 (RGS2) OT0FSRW7 RGS2_HUMAN Decreases Expression [35]
Patatin-like phospholipase domain-containing protein 4 (PNPLA4) OT5CVDJM PLPL4_HUMAN Decreases Expression [35]
Neuroblastoma suppressor of tumorigenicity 1 (NBL1) OTT37U4O NBL1_HUMAN Decreases Expression [35]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9) OTV9L89D TNFL9_HUMAN Decreases Expression [35]
T-lymphocyte activation antigen CD86 (CD86) OTJCSBPC CD86_HUMAN Decreases Expression [35]
Signal transducer and activator of transcription 5A (STAT5A) OTBSJGN3 STA5A_HUMAN Decreases Expression [35]
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2) OTGLVWOP THIM_HUMAN Increases Expression [35]
Stromal cell-derived factor 1 (CXCL12) OT2QX5LL SDF1_HUMAN Increases Expression [35]
Paxillin (PXN) OTVMMUOF PAXI_HUMAN Increases Expression [35]
Natural resistance-associated macrophage protein 1 (SLC11A1) OTCN8N8B NRAM1_HUMAN Decreases Expression [35]
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) OT50L4XB ACADV_HUMAN Increases Expression [35]
Regulator of G-protein signaling 4 (RGS4) OTG94HHL RGS4_HUMAN Decreases Expression [35]
Tuberin (TSC2) OT47LWI9 TSC2_HUMAN Increases Expression [35]
Selenoprotein P (SELENOP) OT02B8IR SEPP1_HUMAN Increases Expression [35]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) OTI862QH CPT1A_HUMAN Increases Expression [35]
Serpin H1 (SERPINH1) OTKGI7BS SERPH_HUMAN Decreases Expression [35]
Peroxisomal multifunctional enzyme type 2 (HSD17B4) OT8733D7 DHB4_HUMAN Increases Expression [35]
Eotaxin (CCL11) OT3BIFPK CCL11_HUMAN Decreases Expression [35]
Tyrosine-protein kinase JAK3 (JAK3) OTQ8QW2L JAK3_HUMAN Decreases Expression [35]
Rho GDP-dissociation inhibitor 2 (ARHGDIB) OT9PD6CS GDIR2_HUMAN Decreases Expression [35]
GTP-binding protein GEM (GEM) OT6SK8ZV GEM_HUMAN Decreases Expression [35]
Fibroblast growth factor 8 (FGF8) OTFU0IUW FGF8_HUMAN Decreases Expression [35]
Microfibril-associated glycoprotein 4 (MFAP4) OT5W64QY MFAP4_HUMAN Decreases Expression [35]
Trifunctional enzyme subunit beta, mitochondrial (HADHB) OT4Y1I62 ECHB_HUMAN Increases Expression [35]
Proteinase-activated receptor 2 (F2RL1) OTMRMJ8N PAR2_HUMAN Increases Expression [35]
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) OT7B6C6M ATP68_HUMAN Decreases Expression [35]
SCAN domain-containing protein 1 (SCAND1) OTRG0AGH SCND1_HUMAN Decreases Expression [35]
CD81 antigen (CD81) OTQFXNAZ CD81_HUMAN Increases Expression [35]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Increases Expression [35]
Large ribosomal subunit protein uL24 (RPL26) OTFNRC27 RL26_HUMAN Decreases Expression [35]
Fibroblast growth factor 12 (FGF12) OTBM9QIO FGF12_HUMAN Decreases Expression [35]
Proline-rich protein 3 (PRR3) OTCWSM5T PRR3_HUMAN Decreases Expression [35]
C-C motif chemokine 8 (CCL8) OTCTWYN8 CCL8_HUMAN Decreases Expression [35]
Small EDRK-rich factor 2 (SERF2) OTZQDYCZ SERF2_HUMAN Decreases Expression [35]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Increases Expression [35]
Transcription factor RelB (RELB) OTU3QYEF RELB_HUMAN Decreases Expression [35]
Interleukin-1 receptor-like 1 (IL1RL1) OTJ6MW31 ILRL1_HUMAN Decreases Expression [35]
Inositol polyphosphate 5-phosphatase OCRL (OCRL) OTQ3L42N OCRL_HUMAN Increases Expression [35]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Decreases Expression [35]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) OTF6OC66 GCNT1_HUMAN Increases Expression [35]
Cytochrome P450 4A11 (CYP4A11) OTPU5J0S CP4AB_HUMAN Increases Expression [35]
Peroxisome proliferator-activated receptor delta (PPARD) OTI4WTOP PPARD_HUMAN Decreases Expression [35]
Acetylcholine receptor subunit epsilon (CHRNE) OTGGXGGB ACHE_HUMAN Decreases Expression [35]
Dual specificity protein phosphatase 2 (DUSP2) OTH54FMR DUS2_HUMAN Decreases Expression [35]
Tumor necrosis factor receptor superfamily member 9 (TNFRSF9) OTNOM26L TNR9_HUMAN Decreases Expression [35]
Peroxisome proliferator-activated receptor alpha (PPARA) OTK095PP PPARA_HUMAN Increases Expression [35]
Regulator of G-protein signaling 1 (RGS1) OTGXJYMG RGS1_HUMAN Decreases Expression [35]
Peroxisomal bifunctional enzyme (EHHADH) OTBAAHL5 ECHP_HUMAN Increases Expression [35]
Cytochrome P450 4F3 (CYP4F3) OTYNSQAM CP4F3_HUMAN Increases Expression [35]
Leukocyte surface antigen CD47 (CD47) OTLDZ0KZ CD47_HUMAN Decreases Expression [35]
Nuclear factor of activated T-cells, cytoplasmic 3 (NFATC3) OTYOORME NFAC3_HUMAN Increases Expression [35]
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) OTA0UNHM ECH1_HUMAN Increases Expression [35]
TNF receptor-associated factor 3 (TRAF3) OT5TQBGV TRAF3_HUMAN Increases Expression [35]
Natural killer cells antigen CD94 (KLRD1) OTMYLOV4 KLRD1_HUMAN Decreases Expression [35]
Interleukin-15 receptor subunit alpha (IL15RA) OTXP1QC5 I15RA_HUMAN Decreases Expression [35]
Myotubularin (MTM1) OT3B517W MTM1_HUMAN Increases Expression [35]
Methylglutaconyl-CoA hydratase, mitochondrial (AUH) OT8VKBXX AUHM_HUMAN Increases Expression [35]
Pro-interleukin-16 (IL16) OTZ2MO6B IL16_HUMAN Decreases Expression [35]
Interleukin-18 (IL18) OTBB2A8O IL18_HUMAN Increases Expression [35]
Next to BRCA1 gene 1 protein (NBR1) OTVRL7J9 NBR1_HUMAN Increases Expression [35]
EKC/KEOPS complex subunit LAGE3 (LAGE3) OTKBQHZI LAGE3_HUMAN Decreases Expression [35]
Signal transducer and activator of transcription 4 (STAT4) OTAK3VFR STAT4_HUMAN Increases Expression [35]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Expression [35]
Neutrophil cytosol factor 4 (NCF4) OTX007YL NCF4_HUMAN Decreases Expression [35]
Splicing factor 3B subunit 3 (SF3B3) OTAC9LZT SF3B3_HUMAN Decreases Expression [35]
Protein transport protein Sec23B (SEC23B) OT2NFSIQ SC23B_HUMAN Decreases Expression [35]
Metastasis-suppressor KiSS-1 (KISS1) OT6IE3K2 KISS1_HUMAN Decreases Expression [35]
Probable E3 ubiquitin-protein ligase HERC1 (HERC1) OT73FVYZ HERC1_HUMAN Increases Expression [35]
Interleukin-17A (IL17A) OTY72FT2 IL17_HUMAN Decreases Expression [35]
Prostacyclin synthase (PTGIS) OTT3RW6N PTGIS_HUMAN Decreases Expression [35]
Keratin, type II cytoskeletal 71 (KRT71) OTI91X9Z K2C71_HUMAN Decreases Expression [35]
Pyrroline-5-carboxylate reductase 3 (PYCR3) OT3SHY2S P5CR3_HUMAN Decreases Expression [35]
Torsin-2A (TOR2A) OT1EGCDU TOR2A_HUMAN Decreases Expression [35]
Collectin-12 (COLEC12) OTIQTK9G COL12_HUMAN Decreases Expression [35]
ER membrane protein complex subunit 10 (EMC10) OTQ6S50X EMC10_HUMAN Decreases Expression [35]
Protein angel homolog 2 (ANGEL2) OT2Q1KU5 ANGE2_HUMAN Increases Expression [35]
Nucleoredoxin (NXN) OT35N40G NXN_HUMAN Decreases Expression [35]
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) OTU2VHWR HIBCH_HUMAN Increases Expression [35]
Nucleolus and neural progenitor protein (NEPRO) OTE5H49L NEPRO_HUMAN Increases Expression [35]
Long-chain fatty acid transport protein 1 (SLC27A1) OTK03OZN S27A1_HUMAN Decreases Expression [35]
Kelch domain-containing protein 10 (KLHDC10) OTLDF1OX KLD10_HUMAN Increases Expression [35]
Mucin-6 (MUC6) OTPVL723 MUC6_HUMAN Decreases Expression [35]
Cytochrome P450 4V2 (CYP4V2) OTQKNK0D CP4V2_HUMAN Increases Expression [35]
Fatty acid 2-hydroxylase (FA2H) OT8HA13U FA2H_HUMAN Decreases Expression [35]
Phospholipid phosphatase-related protein type 4 (PLPPR4) OTBOWTC5 PLPR4_HUMAN Decreases Expression [35]
Adiponectin receptor protein 2 (ADIPOR2) OT2HDTL8 PAQR2_HUMAN Increases Expression [35]
Ras-specific guanine nucleotide-releasing factor RalGPS2 (RALGPS2) OTOYS0SD RGPS2_HUMAN Increases Expression [35]
SURP and G-patch domain-containing protein 2 (SUGP2) OTPUUJYX SUGP2_HUMAN Increases Expression [35]
Spindle and kinetochore-associated protein 3 (SKA3) OTLHEVJD SKA3_HUMAN Decreases Expression [35]
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) OT5Q6SVK SIR2_HUMAN Decreases Expression [35]
Threonine synthase-like 1 (THNSL1) OTQNFH3E THNS1_HUMAN Decreases Expression [35]
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) OT0HFPCD LIRB2_HUMAN Decreases Expression [35]
Coiled-coil domain-containing protein 82 (CCDC82) OT16EAZ7 CCD82_HUMAN Increases Expression [35]
Leucine repeat adapter protein 25 (FAM89B) OT11J9HL LRA25_HUMAN Decreases Expression [35]
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (MINDY1) OTVLF4G5 MINY1_HUMAN Increases Expression [35]
Programmed cell death protein 7 (PDCD7) OTK5YO7J PDCD7_HUMAN Increases Expression [35]
Trinucleotide repeat-containing gene 6A protein (TNRC6A) OT493IOM TNR6A_HUMAN Increases Expression [35]
Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1) OTA1STFZ LIRB1_HUMAN Decreases Expression [35]
N-lysine methyltransferase SETD6 (SETD6) OTH5APN1 SETD6_HUMAN Increases Expression [35]
DmX-like protein 2 (DMXL2) OTB4JWN3 DMXL2_HUMAN Increases Expression [35]
DIS3-like exonuclease 1 (DIS3L) OTYWZ4EM DI3L1_HUMAN Increases Expression [35]
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIL4) OTFTLFJS PPIL4_HUMAN Increases Expression [35]
Spindle and kinetochore-associated protein 2 (SKA2) OTVYF4XT SKA2_HUMAN Decreases Expression [35]
Fatty acyl-CoA reductase 1 (FAR1) OTLHTYIE FACR1_HUMAN Decreases Expression [35]
Solute carrier organic anion transporter family member 2A1 (SLCO2A1) OT3062CA SO2A1_HUMAN Decreases Expression [35]
Glycine N-acyltransferase-like protein 1 (GLYATL1) OTS8JSRY GLYL1_HUMAN Increases Expression [35]
Adiponectin receptor protein 1 (ADIPOR1) OT65ZFZN PAQR1_HUMAN Increases Expression [35]
Probable inactive tRNA-specific adenosine deaminase-like protein 3 (ADAT3) OTMEU45R ADAT3_HUMAN Decreases Expression [35]
Multidrug and toxin extrusion protein 1 (SLC47A1) OTZX0U5Q S47A1_HUMAN Increases Expression [35]
Kelch domain-containing protein 7B (KLHDC7B) OT2H5BNX KLD7B_HUMAN Decreases Expression [35]
RUS family member 1 (RUSF1) OTRIIY6J RUSF1_HUMAN Decreases Expression [35]
Hematopoietic SH2 domain-containing protein (HSH2D) OTOGB2BR HSH2D_HUMAN Increases Expression [35]
Mas-related G-protein coupled receptor member X2 (MRGPRX2) OT2XA799 MRGX2_HUMAN Decreases Expression [35]
Cilia- and flagella-associated protein 44 (CFAP44) OT1273MD CFA44_HUMAN Increases Expression [35]
Diacylglycerol O-acyltransferase 2 (DGAT2) OTE5PDD0 DGAT2_HUMAN Increases Expression [35]
Inositol polyphosphate-4-phosphatase type I A (INPP4A) OT8FZB8T INP4A_HUMAN Decreases Expression [35]
Granulocyte colony-stimulating factor receptor (CSF3R) OTXRAY6X CSF3R_HUMAN Decreases Expression [35]
Transcription factor 12 (TCF12) OTZVONNU HTF4_HUMAN Increases Expression [35]
C-C motif chemokine 13 (CCL13) OTNX0JD0 CCL13_HUMAN Decreases Expression [35]
Zinc finger protein Gfi-1 (GFI1) OT9HB9H8 GFI1_HUMAN Decreases Expression [35]
C-C motif chemokine 19 (CCL19) OTQ2UJMH CCL19_HUMAN Decreases Expression [35]
Endothelial PAS domain-containing protein 1 (EPAS1) OTRE3O8U EPAS1_HUMAN Increases Expression [35]
Adenine nucleotide translocase lysine N-methyltransferase (ANTKMT) OTDV54V6 ANKMT_HUMAN Decreases Expression [35]
Protein FAM167B (FAM167B) OT45SD3K F167B_HUMAN Decreases Expression [35]
Enoyl- reductase, mitochondrial (MECR) OTJQ5XKQ MECR_HUMAN Increases Expression [35]
Peroxisomal trans-2-enoyl-CoA reductase (PECR) OT5MS8EM PECR_HUMAN Increases Expression [35]
Ras-related protein Rab-6C (RAB6C) OTA66R5E RAB6C_HUMAN Decreases Expression [35]
Semaphorin-4A (SEMA4A) OT8901H3 SEM4A_HUMAN Decreases Expression [35]
UPF0488 protein C8orf33 (C8ORF33) OTFCF3V5 CH033_HUMAN Decreases Expression [35]
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (RSAD1) OTHNSDGW RSAD1_HUMAN Increases Expression [35]
MLX-interacting protein (MLXIP) OT30UNI7 MLXIP_HUMAN Increases Expression [35]
Solute carrier family 38 member 10 (SLC38A10) OTXPUL6S S38AA_HUMAN Decreases Expression [35]
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) OTPGYWKC NOD2_HUMAN Decreases Expression [35]
Mineralization regulator ANKH (ANKH) OTCN25R5 ANKH_HUMAN Increases Expression [35]
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) OTR1XD9B GPAT1_HUMAN Increases Expression [35]
Complement component C1q receptor (CD93) OT6HZT6H C1QR1_HUMAN Decreases Expression [35]
Achaete-scute homolog 3 (ASCL3) OT1Y3M4K ASCL3_HUMAN Decreases Expression [35]
Protein transport protein Sec31B (SEC31B) OTHV632I SC31B_HUMAN Increases Expression [35]
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) OTB1FZJU ACSA_HUMAN Increases Expression [35]
Sphingosine kinase 2 (SPHK2) OTNFG52M SPHK2_HUMAN Decreases Expression [35]
Interleukin-17 receptor B (IL17RB) OT0KDNSF I17RB_HUMAN Increases Expression [35]
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) OTAUR5TG PLCC_HUMAN Increases Expression [35]
Keratin, type II cuticular Hb2 (KRT82) OT8Y9T1U KRT82_HUMAN Decreases Expression [35]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3) OTR4990X PLPL3_HUMAN Increases Expression [35]
PI-PLC X domain-containing protein 1 (PLCXD1) OTU7KCQL PLCX1_HUMAN Increases Expression [35]
Interleukin-1 receptor-associated kinase 4 (IRAK4) OT9JTJWC IRAK4_HUMAN Increases Expression [35]
Sphingosine kinase 1 (SPHK1) OTWYPBVD SPHK1_HUMAN Decreases Expression [35]
Protein Mis18-alpha (MIS18A) OTD80K5X MS18A_HUMAN Decreases Expression [35]
Protein CLN8 (CLN8) OT0D4CB5 CLN8_HUMAN Increases Expression [35]
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) OTM3H5OA MALT1_HUMAN Increases Expression [35]
Prenylcysteine oxidase 1 (PCYOX1) OT8FBKY0 PCYOX_HUMAN Increases Expression [35]
Alpha-methylacyl-CoA racemase (AMACR) OTUU22PK AMACR_HUMAN Increases Expression [35]
A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7) OTVKZ1DV ATS7_HUMAN Decreases Expression [35]
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) OT0TT8P8 ACSL6_HUMAN Increases Expression [35]
Teneurin-1 (TENM1) OTSKSU4V TEN1_HUMAN Decreases Expression [35]
Serine/threonine-protein kinase TAO2 (TAOK2) OTNUMOZ1 TAOK2_HUMAN Decreases Expression [35]
Two pore channel protein 1 (TPCN1) OTT4C4DI TPC1_HUMAN Increases Expression [35]
Apelin (APLN) OTSWJD7B APEL_HUMAN Decreases Expression [35]
Myotubularin-related protein 7 (MTMR7) OT47NVYM MTMR7_HUMAN Decreases Expression [35]
Ninein-like protein (NINL) OTWIK6HT NINL_HUMAN Increases Expression [35]
Potassium channel subfamily K member 7 (KCNK7) OTFJOWT4 KCNK7_HUMAN Decreases Expression [35]
Krueppel-like factor 2 (KLF2) OTIP1UFX KLF2_HUMAN Decreases Expression [35]
Neuroplastin (NPTN) OTAQKSAU NPTN_HUMAN Decreases Expression [35]
Inositol 1,4,5-triphosphate receptor associated 1 (IRAG1) OTMRW5U5 IRAG1_HUMAN Decreases Expression [35]
Mitochondrial inner membrane protease ATP23 homolog (ATP23) OT303R2T ATP23_HUMAN Increases Expression [35]
Lymphocyte antigen 96 (LY96) OTN4HXA2 LY96_HUMAN Decreases Expression [35]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Increases Expression [84]
Sterol 26-hydroxylase, mitochondrial (CYP27A1) OT649C01 CP27A_HUMAN Increases Expression [84]
CCN family member 1 (CCN1) OTKJBEMD CCN1_HUMAN Increases Expression [36]
Phospholipid phosphatase 3 (PLPP3) OTSSF7BK PLPP3_HUMAN Decreases Expression [36]
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) OTPGHZB9 IFIT3_HUMAN Decreases Expression [36]
Calmegin (CLGN) OTEWVFQV CLGN_HUMAN Decreases Expression [36]
D-3-phosphoglycerate dehydrogenase (PHGDH) OT1LMRTG SERA_HUMAN Decreases Expression [36]
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) OT0KMIYQ RIPK2_HUMAN Decreases Expression [36]
Gasdermin-E (GSDME) OT1ZWY32 GSDME_HUMAN Decreases Expression [36]
Toll-like receptor 2 (TLR2) OTGO5P4R TLR2_HUMAN Decreases Expression [36]
Ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3) OTDA431Y ENTP3_HUMAN Increases Expression [36]
Antiviral innate immune response receptor RIG-I (RIGI) OTFIIC43 RIGI_HUMAN Decreases Expression [36]
2'-5'-oligoadenylate synthase 1 (OAS1) OT8ZLOCY OAS1_HUMAN Decreases Expression [36]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Decreases Expression [36]
Ubiquitin-like protein ISG15 (ISG15) OT53QQ7N ISG15_HUMAN Decreases Expression [36]
Fibroblast growth factor 1 (FGF1) OT8I64X8 FGF1_HUMAN Increases Expression [36]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Decreases Expression [36]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Decreases Expression [36]
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Decreases Expression [36]
Steryl-sulfatase (STS) OTXTJQPC STS_HUMAN Increases Expression [36]
Neuromedin-B (NMB) OT4NLN6H NMB_HUMAN Decreases Expression [36]
Stromelysin-2 (MMP10) OTJDWW8Q MMP10_HUMAN Decreases Expression [36]
Interferon alpha-inducible protein 6 (IFI6) OTWOOAM4 IFI6_HUMAN Decreases Expression [36]
Interleukin-1 receptor antagonist protein (IL1RN) OT308CBE IL1RA_HUMAN Decreases Expression [36]
Interferon-induced GTP-binding protein Mx1 (MX1) OT6X8G5T MX1_HUMAN Decreases Expression [36]
Fibroblast growth factor 7 (FGF7) OTGK6ANL FGF7_HUMAN Increases Expression [36]
Fibulin-1 (FBLN1) OT5MHHOP FBLN1_HUMAN Increases Expression [36]
Atypical chemokine receptor 3 (ACKR3) OTA6GA4F ACKR3_HUMAN Decreases Expression [36]
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1) OTO7FJA9 DHI1_HUMAN Decreases Expression [36]
Myristoylated alanine-rich C-kinase substrate (MARCKS) OT7N056G MARCS_HUMAN Decreases Expression [36]
Guanylate-binding protein 1 (GBP1) OTUM7RPJ GBP1_HUMAN Decreases Expression [36]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Decreases Expression [36]
Macrophage metalloelastase (MMP12) OT9Z7LHM MMP12_HUMAN Decreases Expression [36]
Interferon alpha-inducible protein 27, mitochondrial (IFI27) OTI2XGIT IFI27_HUMAN Decreases Expression [36]
Signal transducer and activator of transcription 1-alpha/beta (STAT1) OTLMBUZ6 STAT1_HUMAN Decreases Expression [36]
Retinoic acid receptor responder protein 1 (RARRES1) OTETUPP5 TIG1_HUMAN Increases Expression [36]
Prolargin (PRELP) OT9EEBUJ PRELP_HUMAN Increases Expression [36]
Spermine synthase (SMS) OT8JYKNH SPSY_HUMAN Decreases Expression [36]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Decreases Expression [36]
C-C motif chemokine 20 (CCL20) OTUCJY4N CCL20_HUMAN Decreases Expression [36]
Interferon-induced 35 kDa protein (IFI35) OTV9RZ53 IN35_HUMAN Decreases Expression [36]
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2) OTRZH80H TNAP2_HUMAN Decreases Expression [36]
Bone marrow stromal antigen 2 (BST2) OTU4LCJV BST2_HUMAN Decreases Expression [36]
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) OTZVUOOB FBLN3_HUMAN Increases Expression [36]
Probable ATP-dependent RNA helicase DDX10 (DDX10) OTH48438 DDX10_HUMAN Increases Expression [36]
Neuronal membrane glycoprotein M6-b (GPM6B) OT8Q1582 GPM6B_HUMAN Increases Expression [36]
Laminin subunit beta-3 (LAMB3) OTFPU6W8 LAMB3_HUMAN Decreases Expression [36]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) OTTUU92F ENPP2_HUMAN Increases Expression [36]
Nidogen-2 (NID2) OTHC33FF NID2_HUMAN Increases Expression [36]
Lymphocyte antigen 6E (LY6E) OTMG16BZ LY6E_HUMAN Decreases Expression [36]
Interferon-induced protein 44-like (IFI44L) OTXKORJP IF44L_HUMAN Decreases Expression [36]
E3 ubiquitin-protein ligase RNF19B (RNF19B) OTYCWKBP RN19B_HUMAN Decreases Expression [36]
Amphoterin-induced protein 2 (AMIGO2) OTPAIT1O AMGO2_HUMAN Decreases Expression [36]
Probable E3 ubiquitin-protein ligase HERC6 (HERC6) OT7G9PQE HERC6_HUMAN Decreases Expression [36]
Interferon-induced protein 44 (IFI44) OTOKSZVA IFI44_HUMAN Decreases Expression [36]
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2) OTCA9WCM RSAD2_HUMAN Decreases Expression [36]
Nuclear receptor subfamily 4 group A member 3 (NR4A3) OTPBE9R1 NR4A3_HUMAN Decreases Expression [36]
Interferon-stimulated gene 20 kDa protein (ISG20) OTCWRJJW ISG20_HUMAN Decreases Expression [36]
Latexin (LXN) OTZQ2M6Y LXN_HUMAN Increases Expression [36]
Interferon-induced helicase C domain-containing protein 1 (IFIH1) OTZA2AHA IFIH1_HUMAN Decreases Expression [36]
Anthrax toxin receptor 1 (ANTXR1) OT5W1GPC ANTR1_HUMAN Increases Expression [36]
Spondin-1 (SPON1) OTC06MY4 SPON1_HUMAN Increases Expression [36]
Interleukin-23 subunit alpha (IL23A) OTYO99HC IL23A_HUMAN Decreases Expression [36]
Matrix-remodeling-associated protein 5 (MXRA5) OTXZBWCU MXRA5_HUMAN Increases Expression [36]
NADH dehydrogenase 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2) OTK0PG7R NUA4L_HUMAN Decreases Expression [36]
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2) OT7FCZRM PP4R2_HUMAN Increases Expression [36]
Large neutral amino acids transporter small subunit 2 (SLC7A8) OT8XXVO8 LAT2_HUMAN Increases Expression [36]
Cystine/glutamate transporter (SLC7A11) OTKJ6PXW XCT_HUMAN Decreases Expression [36]
Hypoxia-inducible lipid droplet-associated protein (HILPDA) OTEID3ZM HLPDA_HUMAN Decreases Expression [36]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) OTBPCU2O TR10A_HUMAN Increases Expression [38]
Claudin-4 (CLDN4) OT9C4PZ4 CLD4_HUMAN Increases Expression [38]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Increases Expression [38]
Neuropilin-1 (NRP1) OTCGULYV NRP1_HUMAN Increases Expression [38]
Proepiregulin (EREG) OTRM4NQY EREG_HUMAN Increases Expression [38]
Myosin regulatory light chain 12B (MYL12B) OTXMLQOT ML12B_HUMAN Increases Expression [38]
Toll-like receptor 3 (TLR3) OT8QPYXZ TLR3_HUMAN Increases Expression [38]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Increases Expression [38]
Semaphorin-7A (SEMA7A) OT0ZJK64 SEM7A_HUMAN Increases Expression [38]
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) OT3EDGXO TNR21_HUMAN Increases Expression [38]
Ubiquitin-like protein ATG12 (ATG12) OTJRO09Y ATG12_HUMAN Increases Expression [38]
Tight junction protein ZO-3 (TJP3) OTC1K8HC ZO3_HUMAN Increases Expression [38]
Tumor necrosis factor ligand superfamily member 15 (TNFSF15) OTNGA2BW TNF15_HUMAN Increases Expression [38]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Increases Expression [38]
Claudin-7 (CLDN7) OTNE0XHQ CLD7_HUMAN Increases Expression [38]
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) OTBMJUOC M4K4_HUMAN Increases Expression [38]
Claudin-1 (CLDN1) OT27KV99 CLD1_HUMAN Increases Expression [38]
Tissue-type plasminogen activator (PLAT) OTQPDNAB TPA_HUMAN Increases Expression [38]
Prelamin-A/C (LMNA) OT3SG7ZR LMNA_HUMAN Increases Expression [38]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Increases Expression [38]
Platelet-derived growth factor subunit A (PDGFA) OTCMZ0W8 PDGFA_HUMAN Increases Expression [38]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Increases Expression [38]
Integrin beta-2 (ITGB2) OTEKPEPR ITB2_HUMAN Increases Expression [38]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Increases Expression [38]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Increases Expression [38]
Cholecystokinin (CCK) OT1GCG0L CCKN_HUMAN Increases Expression [38]
Gelsolin (GSN) OT4KS2UU GELS_HUMAN Increases Expression [38]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Expression [38]
Glia-derived nexin (SERPINE2) OTYF5340 GDN_HUMAN Increases Expression [38]
Extracellular superoxide dismutase (SOD3) OTIOZQAB SODE_HUMAN Increases Expression [38]
Matrilysin (MMP7) OTVT3SEJ MMP7_HUMAN Increases Expression [38]
Clathrin light chain B (CLTB) OTPW9VRE CLCB_HUMAN Increases Expression [38]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [38]
Calmodulin-1 (CALM2) OTNYA92F CALM1_HUMAN Increases Expression [38]
Ras-related protein R-Ras (RRAS) OTBBF28C RRAS_HUMAN Increases Expression [38]
Interferon regulatory factor 1 (IRF1) OT43DI6J IRF1_HUMAN Increases Expression [38]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Decreases Expression [38]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Increases Expression [38]
Bone morphogenetic protein 1 (BMP1) OTRFFAL4 BMP1_HUMAN Increases Expression [38]
Leukemia inhibitory factor (LIF) OTO46S5S LIF_HUMAN Increases Expression [38]
Interferon gamma receptor 1 (IFNGR1) OTCTQBWW INGR1_HUMAN Increases Expression [38]
Ezrin (EZR) OTHBPF1Z EZRI_HUMAN Increases Expression [38]
Integrin beta-4 (ITGB4) OT28UK84 ITB4_HUMAN Increases Expression [38]
Beta-galactosidase (GLB1) OTB0TKAG BGAL_HUMAN Increases Expression [38]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) OTPGAU0U AT2A2_HUMAN Increases Expression [38]
Amine oxidase A (MAOA) OT8NIWMQ AOFA_HUMAN Increases Expression [38]
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) OTMWFDAC AT2B4_HUMAN Increases Expression [38]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Increases Expression [38]
Interleukin-4 receptor subunit alpha (IL4R) OTTXOTCW IL4RA_HUMAN Increases Expression [38]
Insulin-like growth factor-binding protein 6 (IGFBP6) OTW878VI IBP6_HUMAN Increases Expression [38]
Integrin alpha-3 (ITGA3) OTBCH21D ITA3_HUMAN Increases Expression [38]
Integrin beta-8 (ITGB8) OTP4HSHG ITB8_HUMAN Increases Expression [38]
Amine oxidase B (MAOB) OTTDFM1O AOFB_HUMAN Increases Expression [38]
Proteasome subunit beta type-8 (PSMB8) OTW5XGMF PSB8_HUMAN Increases Expression [38]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Increases Expression [38]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Increases Expression [38]
M-phase inducer phosphatase 3 (CDC25C) OTPQI71S MPIP3_HUMAN Decreases Expression [38]
Leukocyte elastase inhibitor (SERPINB1) OT5RDUFO ILEU_HUMAN Increases Expression [38]
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B) OT777OHS KAP1_HUMAN Increases Expression [38]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Increases Expression [38]
Nitric oxide synthase, inducible (NOS2) OTKKIOJ1 NOS2_HUMAN Increases Expression [38]
Metalloproteinase inhibitor 3 (TIMP3) OTDGQAD1 TIMP3_HUMAN Increases Expression [38]
Tumor necrosis factor receptor superfamily member 3 (LTBR) OT2HVZGV TNR3_HUMAN Increases Expression [38]
Serpin B5 (SERPINB5) OTSMXQRJ SPB5_HUMAN Increases Expression [38]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Increases Expression [38]
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) OTV232Y7 GPDM_HUMAN Increases Expression [38]
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4) OTZPZX11 MP2K4_HUMAN Increases Expression [38]
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PPP3CC) OT0AQD93 PP2BC_HUMAN Increases Expression [38]
Presenilin-1 (PSEN1) OTKL39RT PSN1_HUMAN Increases Expression [38]
Matrix metalloproteinase-15 (MMP15) OT1XF517 MMP15_HUMAN Increases Expression [38]
Interleukin-1 receptor-associated kinase 1 (IRAK1) OT133G8J IRAK1_HUMAN Increases Expression [38]
Cyclin-G1 (CCNG1) OT17IA9L CCNG1_HUMAN Increases Expression [38]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Expression [38]
Transforming protein RhoA (RHOA) OT6YOJ9N RHOA_HUMAN Increases Expression [38]
Interleukin-13 receptor subunit alpha-1 (IL13RA1) OT59OYXP I13R1_HUMAN Increases Expression [38]
Nuclear factor NF-kappa-B p100 subunit (NFKB2) OTS231V7 NFKB2_HUMAN Increases Expression [38]
E3 ubiquitin-protein ligase Mdm2 (MDM2) OTOVXARF MDM2_HUMAN Increases Expression [38]
2-oxoglutarate dehydrogenase complex component E1 (OGDH) OTHGTQWF ODO1_HUMAN Increases Expression [38]
Pro-neuregulin-1, membrane-bound isoform (NRG1) OTZO6F1X NRG1_HUMAN Increases Expression [38]
Max dimerization protein 1 (MXD1) OTS5CTHX MAD1_HUMAN Increases Expression [38]
Peroxiredoxin-1 (PRDX1) OTZ3BEC4 PRDX1_HUMAN Increases Expression [38]
Tight junction protein ZO-1 (TJP1) OTBDCUPK ZO1_HUMAN Increases Expression [38]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [38]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Increases Expression [38]
Peptidyl-prolyl cis-trans isomerase D (PPID) OT2CDF7W PPID_HUMAN Increases Expression [38]
Mitogen-activated protein kinase 7 (MAPK7) OTF7H7L7 MK07_HUMAN Increases Expression [38]
Serine/threonine-protein kinase PAK 2 (PAK2) OTLUNCIH PAK2_HUMAN Increases Expression [38]
Semaphorin-3B (SEMA3B) OTCZCPMS SEM3B_HUMAN Increases Expression [38]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Increases Expression [38]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Increases Expression [38]
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) OTHD9KJG KCC2G_HUMAN Increases Expression [38]
Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D) OTJ5XLVU KCC2D_HUMAN Increases Expression [38]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) OT6VY3A3 SPTN1_HUMAN Increases Expression [38]
Beclin-1 (BECN1) OT4X293M BECN1_HUMAN Increases Expression [38]
Semaphorin-3A (SEMA3A) OTQJSV7W SEM3A_HUMAN Increases Expression [38]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3) OTGQ2AOJ ITPR3_HUMAN Increases Expression [38]
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) OTX7MWW1 ITPR1_HUMAN Increases Expression [38]
Glutamate receptor ionotropic, NMDA 2C (GRIN2C) OTV7ZA9O NMDE3_HUMAN Increases Expression [38]
Toll-like receptor 1 (TLR1) OTZTQIZO TLR1_HUMAN Increases Expression [38]
Mitogen-activated protein kinase 11 (MAPK11) OT0AS010 MK11_HUMAN Increases Expression [38]
Cystatin-M (CST6) OTZVHJTF CYTM_HUMAN Increases Expression [38]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [38]
MHC class I polypeptide-related sequence B (MICB) OTS2DVDW MICB_HUMAN Increases Expression [38]
Quinone oxidoreductase PIG3 (TP53I3) OTSCM68G QORX_HUMAN Increases Expression [38]
Autophagy-related protein 16-1 (ATG16L1) OTEOYC5D A16L1_HUMAN Increases Expression [38]
Cytochrome c oxidase subunit 6B2 (COX6B2) OT5KU3VV CX6B2_HUMAN Increases Expression [38]
Rho-related GTP-binding protein RhoU (RHOU) OTERIAD4 RHOU_HUMAN Increases Expression [38]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) OTE8GBUR RIR2B_HUMAN Increases Expression [38]
Cysteine protease ATG4D (ATG4D) OTSWUO4R ATG4D_HUMAN Increases Expression [38]
TIR domain-containing adapter molecule 1 (TICAM1) OTK6Y1HK TCAM1_HUMAN Increases Expression [38]
DNA damage-regulated autophagy modulator protein 1 (DRAM1) OTIJTXEN DRAM1_HUMAN Increases Expression [38]
Interleukin-22 receptor subunit alpha-1 (IL22RA1) OTGVKLBR I22R1_HUMAN Increases Expression [38]
Protein Atg16l2 (ATG16L2) OTJYU0W8 A16L2_HUMAN Increases Expression [38]
Cysteine protease ATG4A (ATG4A) OTDHXAPG ATG4A_HUMAN Increases Expression [38]
Histone acetyltransferase KAT2B (KAT2B) OTWQITWK KAT2B_HUMAN Increases Expression [38]
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) OTVZ7I3A TNR25_HUMAN Increases Expression [38]
Tumor protein p53-inducible nuclear protein 1 (TP53INP1) OT2363Z9 T53I1_HUMAN Increases Expression [38]
Claudin-23 (CLDN23) OTN5RV40 CLD23_HUMAN Increases Expression [38]
p53 apoptosis effector related to PMP-22 (PERP) OTP0YL53 PERP_HUMAN Increases Expression [38]
Rho-related GTP-binding protein RhoV (RHOV) OTW4N3QN RHOV_HUMAN Increases Expression [38]
Mitogen-activated protein kinase kinase kinase 14 (MAP3K14) OTT3DOOL M3K14_HUMAN Increases Expression [38]
Myeloid differentiation primary response protein MyD88 (MYD88) OTB4D6FL MYD88_HUMAN Increases Expression [38]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Increases Expression [38]
Transient receptor potential cation channel subfamily V member 6 (TRPV6) OTZ0LGNO TRPV6_HUMAN Increases Expression [38]
p53-induced death domain-containing protein 1 (PIDD1) OTWFM930 PIDD1_HUMAN Increases Expression [38]
Rho-related GTP-binding protein RhoF (RHOF) OTPA3F8Q RHOF_HUMAN Increases Expression [38]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) OT5V52LN TNR12_HUMAN Increases Expression [38]
Fructose-2,6-bisphosphatase TIGAR (TIGAR) OTR7NMRJ TIGAR_HUMAN Increases Expression [38]
Serine/threonine-protein kinase PAK 6 (PAK6) OTAHPZTT PAK6_HUMAN Increases Expression [38]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2) OTPZK76F TAB2_HUMAN Increases Expression [38]
Cingulin (CGN) OTBCQ8AQ CING_HUMAN Increases Expression [38]
Zinc finger protein PLAGL1 (PLAGL1) OTZAO900 PLAL1_HUMAN Increases Expression [38]
Cytosolic phospholipase A2 gamma (PLA2G4C) OTIK5GT5 PA24C_HUMAN Increases Expression [38]
Cofilin-2 (CFL2) OTE2W0DH COF2_HUMAN Increases Expression [38]
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1) OTYK9JU6 CIA30_HUMAN Increases Expression [38]
Talin-2 (TLN2) OT10QQBC TLN2_HUMAN Increases Expression [38]
Cysteine protease ATG4B (ATG4B) OTQ4RNRM ATG4B_HUMAN Increases Expression [38]
NF-kappa-B essential modulator (IKBKG) OTNWJWSD NEMO_HUMAN Increases Expression [38]
S-adenosylmethionine synthase isoform type-2 (MAT2A) OTFJMIQR METK2_HUMAN Decreases Expression [85]
Serine/threonine-protein kinase Chk1 (CHEK1) OTTTI622 CHK1_HUMAN Increases Expression [86]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Increases Phosphorylation [86]
M-phase inducer phosphatase 1 (CDC25A) OTSLKKCO MPIP1_HUMAN Increases Degradation [86]
Bifunctional purine biosynthesis protein ATIC (ATIC) OT8XE052 PUR9_HUMAN Decreases Expression [74]
Uncharacterized protein C20orf204 (C20ORF204) OT0GVQPP CT204_HUMAN Decreases Expression [39]
Uncharacterized protein CXorf51A (CXORF51A) OTDN5YLP CX05A_HUMAN Increases Expression [39]
Transmembrane protein 120B (TMEM120B) OTA5XMI9 T120B_HUMAN Decreases Expression [39]
Probable ATP-dependent DNA helicase HFM1 (HFM1) OTHV3EFE HFM1_HUMAN Decreases Expression [39]
Homeobox protein HMX2 (HMX2) OTBRXY6D HMX2_HUMAN Increases Expression [39]
Protein FAM181B (FAM181B) OTGZHJ7K F181B_HUMAN Decreases Expression [39]
RNA binding protein fox-1 homolog 3 (RBFOX3) OTL0F3D6 RFOX3_HUMAN Decreases Expression [39]
Protein ANKUB1 (ANKUB1) OT8QXDL8 ANKUB_HUMAN Increases Expression [39]
Olfactory receptor 5H1 (OR5H1) OT9YQR5A OR5H1_HUMAN Increases Expression [39]
Uncharacterized protein C15orf62, mitochondrial (C15ORF62) OT2VU9TN CO062_HUMAN Increases Expression [39]
Espin (ESPN) OT7Z6LX2 ESPN_HUMAN Increases Expression [39]
Sperm axonemal maintenance protein CFAP97D1 (CFAP97D1) OTCPE947 CF97D_HUMAN Increases Expression [39]
Putative adrenomedullin-5-like protein (ADM5) OTFOA92Z ADM5_HUMAN Decreases Expression [39]
Fibronectin type III domain-containing protein 10 (FNDC10) OT06NW7W FND10_HUMAN Decreases Expression [39]
26S proteasome non-ATPase regulatory subunit 9 (PSMD9) OT6Y5CC3 PSMD9_HUMAN Decreases Expression [39]
Signal-regulatory protein beta-1 (SIRPB1) OTGHALWJ SIRB1_HUMAN Increases Expression [39]
Basic helix-loop-helix ARNT-like protein 1 (BMAL1) OTMI12L2 BMAL1_HUMAN Decreases Expression [39]
Sulfotransferase 1C2 (SULT1C2) OT07MMZS ST1C2_HUMAN Increases Expression [39]
C-C chemokine receptor-like 2 (CCRL2) OT5PX0RX CCRL2_HUMAN Decreases Expression [39]
Synaptotagmin-5 (SYT5) OT718PRY SYT5_HUMAN Decreases Expression [39]
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A) OTY08SIX CAC1A_HUMAN Increases Expression [39]
Transcription factor SOX-1 (SOX1) OTVI1RAR SOX1_HUMAN Decreases Expression [39]
C-X-C chemokine receptor type 6 (CXCR6) OTK9R50G CXCR6_HUMAN Decreases Expression [39]
Ribonuclease T2 (RNASET2) OTWY64L7 RNT2_HUMAN Decreases Expression [39]
Ficolin-1 (FCN1) OTK6ZHXH FCN1_HUMAN Decreases Expression [39]
Transcription factor E2F3 (E2F3) OT5VQMWY E2F3_HUMAN Decreases Expression [39]
Cocaine esterase (CES2) OTC647SQ EST2_HUMAN Decreases Expression [39]
Suppressor of cytokine signaling 3 (SOCS3) OTY183WJ SOCS3_HUMAN Decreases Expression [39]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Decreases Expression [39]
Gamma-aminobutyric acid receptor subunit delta (GABRD) OTO38I2R GBRD_HUMAN Decreases Expression [39]
Protein lin-7 homolog A (LIN7A) OTFL3PUX LIN7A_HUMAN Decreases Expression [39]
Guanine nucleotide exchange factor DBS (MCF2L) OTEURA8N MCF2L_HUMAN Increases Expression [39]
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) OT7DVQB0 RPAC1_HUMAN Decreases Expression [39]
Nephrocystin-1 (NPHP1) OTZHCFFQ NPHP1_HUMAN Increases Expression [39]
Cytoplasmic dynein 1 light intermediate chain 2 (DYNC1LI2) OTR7WJES DC1L2_HUMAN Increases Expression [39]
U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3) OTUA4OLZ PRPF3_HUMAN Decreases Expression [39]
Peptidyl-prolyl cis-trans isomerase H (PPIH) OTB3HCLB PPIH_HUMAN Decreases Expression [39]
Potassium voltage-gated channel subfamily KQT member 2 (KCNQ2) OT3CXQJT KCNQ2_HUMAN Decreases Expression [39]
Mothers against decapentaplegic homolog 6 (SMAD6) OTUZZWUD SMAD6_HUMAN Decreases Expression [39]
Neuronal migration protein doublecortin (DCX) OTISR7K3 DCX_HUMAN Increases Expression [39]
A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) OT0L3PZ6 AKA7A_HUMAN Increases Expression [39]
Peptidase inhibitor 15 (PI15) OTPJL6ML PI15_HUMAN Increases Expression [39]
Cytohesin-3 (CYTH3) OTBXAT3Z CYH3_HUMAN Increases Expression [39]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) OTLVN68B AAKB2_HUMAN Increases Expression [39]
Kalirin (KALRN) OT8WRCBH KALRN_HUMAN Increases Expression [39]
Protocadherin-7 (PCDH7) OTP091X8 PCDH7_HUMAN Increases Expression [39]
Adenylate cyclase type 3 (ADCY3) OTGOQM6B ADCY3_HUMAN Decreases Expression [39]
Katanin-interacting protein (KATNIP) OTLLA1BX KATIP_HUMAN Decreases Expression [39]
Centrosomal protein of 104 kDa (CEP104) OTOLRJLH CE104_HUMAN Increases Expression [39]
Germinal-center associated nuclear protein (MCM3AP) OT895FEC GANP_HUMAN Increases Expression [39]
Phospholipid-transporting ATPase IK (ATP8B3) OTZOGEJO AT8B3_HUMAN Decreases Expression [39]
Ecotropic viral integration site 5 protein homolog (EVI5) OTOPAP55 EVI5_HUMAN Increases Expression [39]
Beta-1,4-galactosyltransferase 3 (B4GALT3) OTHX77K8 B4GT3_HUMAN Decreases Expression [39]
Catenin delta-1 (CTNND1) OTUMPSHR CTND1_HUMAN Decreases Expression [39]
Dual specificity protein phosphatase CDC14B (CDC14B) OTAESVOZ CC14B_HUMAN Increases Expression [39]
PRAME family member 11 (PRAMEF11) OT15BWSL PRA11_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase TRIM13 (TRIM13) OTQIUACB TRI13_HUMAN Increases Expression [39]
Short stature homeobox protein 2 (SHOX2) OTLCZZJW SHOX2_HUMAN Increases Expression [39]
mRNA-capping enzyme (RNGTT) OT59E0KX MCE1_HUMAN Increases Expression [39]
Calcium-transporting ATPase type 2C member 2 (ATP2C2) OTGIHTYQ AT2C2_HUMAN Decreases Expression [39]
Transcription initiation protein SPT3 homolog (SUPT3H) OT7B6FRO SUPT3_HUMAN Decreases Expression [39]
DNA-directed RNA polymerase III subunit RPC9 (CRCP) OT4K9BT7 RPC9_HUMAN Decreases Expression [39]
Decapping and exoribonuclease protein (DXO) OTFDTNW4 DXO_HUMAN Decreases Expression [39]
Pre-mRNA-processing factor 6 (PRPF6) OT3U0ABN PRP6_HUMAN Increases Expression [39]
Protein furry homolog-like (FRYL) OTBN3XHN FRYL_HUMAN Increases Expression [39]
Glutaminase kidney isoform, mitochondrial (GLS) OTGOZG2M GLSK_HUMAN Decreases Expression [39]
Lysine-specific demethylase 4B (KDM4B) OT5P1UPY KDM4B_HUMAN Increases Expression [39]
Olfactory receptor 2F2 (OR2F2) OTPYQL7R OR2F2_HUMAN Increases Expression [39]
Olfactory receptor 2A4 (OR2A4) OT70V8VC OR2A4_HUMAN Increases Expression [39]
Sphingosine 1-phosphate receptor 2 (S1PR2) OTRTJF29 S1PR2_HUMAN Increases Expression [39]
Olfactory receptor 6A2 (OR6A2) OTWKCMOD OR6A2_HUMAN Increases Expression [39]
Myelin protein zero-like protein 1 (MPZL1) OTJSUUHR MPZL1_HUMAN Increases Expression [39]
Transforming acidic coiled-coil-containing protein 2 (TACC2) OTW4M7HI TACC2_HUMAN Increases Expression [39]
Mitogen-activated protein kinase kinase kinase 6 (MAP3K6) OTOE0Z1R M3K6_HUMAN Decreases Expression [39]
Sodium-dependent phosphate transport protein 2B (SLC34A2) OTLFMBB0 NPT2B_HUMAN Decreases Expression [39]
Claudin-9 (CLDN9) OTCKI2IZ CLD9_HUMAN Decreases Expression [39]
Neuronal pentraxin receptor (NPTXR) OTQJEOIH NPTXR_HUMAN Increases Expression [39]
Glucagon-like peptide 2 receptor (GLP2R) OTVKNDVL GLP2R_HUMAN Increases Expression [39]
Diphosphoinositol polyphosphate phosphohydrolase 1 (NUDT3) OTXITZUB NUDT3_HUMAN Increases Expression [39]
G1/S-specific cyclin-E2 (CCNE2) OTBBUKQQ CCNE2_HUMAN Decreases Expression [39]
Coagulation factor XIII A chain (F13A1) OTO8O184 F13A_HUMAN Decreases Expression [39]
Haptoglobin-related protein (HPR) OTXSC9UB HPTR_HUMAN Decreases Expression [39]
Urokinase-type plasminogen activator (PLAU) OTX0QGKK UROK_HUMAN Decreases Expression [39]
Protransforming growth factor alpha (TGFA) OTPD1LL9 TGFA_HUMAN Decreases Expression [39]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Decreases Expression [39]
Alpha-2-HS-glycoprotein (AHSG) OTUG0LEA FETUA_HUMAN Increases Expression [39]
Ferritin heavy chain (FTH1) OT6IFS0O FRIH_HUMAN Decreases Expression [39]
Arginase-1 (ARG1) OTHZITAM ARGI1_HUMAN Increases Expression [39]
T-cell surface glycoprotein CD1a (CD1A) OTKSSG6N CD1A_HUMAN Decreases Expression [39]
Prothymosin alpha (PTMA) OT2W4T1M PTMA_HUMAN Decreases Expression [39]
Thrombomodulin (THBD) OT8VHLKY TRBM_HUMAN Decreases Expression [39]
Asialoglycoprotein receptor 2 (ASGR2) OTFSGOVY ASGR2_HUMAN Decreases Expression [39]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Increases Expression [39]
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) OT47AK4C HNRPC_HUMAN Decreases Expression [39]
Tumor necrosis factor receptor superfamily member 16 (NGFR) OTPKSM49 TNR16_HUMAN Decreases Expression [39]
Signal recognition particle receptor subunit alpha (SRPRA) OT5NMYTY SRPRA_HUMAN Decreases Expression [39]
Glutathione S-transferase A1 (GSTA1) OTA7K5XA GSTA1_HUMAN Increases Expression [39]
Beta-1 adrenergic receptor (ADRB1) OTQBWN4U ADRB1_HUMAN Decreases Expression [39]
Fibrocystin (PKHD1) OTAH8SMF PKHD1_HUMAN Decreases Expression [39]
Growth-regulated alpha protein (CXCL1) OT3WCTZV GROA_HUMAN Decreases Expression [39]
Tumor-associated calcium signal transducer 2 (TACSTD2) OTLSZR00 TACD2_HUMAN Decreases Expression [39]
Protein ELFN1 (ELFN1) OTM7M52U ELFN1_HUMAN Decreases Expression [39]
Myocardial zonula adherens protein (MYZAP) OTAZCNBT MYZAP_HUMAN Decreases Expression [39]
A-kinase anchor protein inhibitor 1 (AKAIN1) OTXO2ZVV AKAI1_HUMAN Increases Expression [39]
Paraneoplastic antigen-like protein 6A (PNMA6A) OTW96SNS PNM6A_HUMAN Increases Expression [39]
Endothelin-converting enzyme 2 (ECE2) OTZLNQVL ECE2_HUMAN Increases Expression [39]
Ras-related protein Rap-2a (RAP2A) OT0JB5S4 RAP2A_HUMAN Increases Expression [39]
Transcriptional activator Myb (MYB) OTJH64IV MYB_HUMAN Increases Expression [39]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Decreases Expression [39]
Microtubule-associated protein 2 (MAP2) OT6UYT3X MTAP2_HUMAN Increases Expression [39]
Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2) OTBL2W7R GTR2_HUMAN Increases Expression [39]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) OT2HZK5M GTR3_HUMAN Decreases Expression [39]
Serine/threonine-protein kinase pim-1 (PIM1) OTWEKXTU PIM1_HUMAN Decreases Expression [39]
DNA topoisomerase 1 (TOP1) OT51O0CF TOP1_HUMAN Decreases Expression [39]
Cytochrome P450 2C9 (CYP2C9) OTGLBN29 CP2C9_HUMAN Decreases Expression [39]
Parathyroid hormone-related protein (PTHLH) OTI1JF13 PTHR_HUMAN Increases Expression [39]
Protein L-Myc (MYCL) OT1MFQ5U MYCL_HUMAN Decreases Expression [39]
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) OTU0FC24 COX41_HUMAN Decreases Expression [39]
Interferon-induced transmembrane protein 1 (IFITM1) OTECO1G8 IFM1_HUMAN Decreases Expression [39]
HLA class II histocompatibility antigen, DR beta 4 chain (HLA-DRB4) OTNXIHQU DRB4_HUMAN Decreases Expression [39]
Beta-enolase (ENO3) OT3HYKYI ENOB_HUMAN Increases Expression [39]
Nidogen-1 (NID1) OTKLBLS6 NID1_HUMAN Increases Expression [39]
Homeobox protein Hox-B3 (HOXB3) OT9UC5PE HXB3_HUMAN Increases Expression [39]
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB) OT3UJ4ZU RSMB_HUMAN Decreases Expression [39]
Cyclic AMP-dependent transcription factor ATF-2 (ATF2) OTNIZPEA ATF2_HUMAN Increases Expression [39]
Amphiregulin (AREG) OTJFOR67 AREG_HUMAN Decreases Expression [39]
Histone H1.3 (H1-3) OTT7VPRB H13_HUMAN Increases Expression [39]
Natriuretic peptides B (NPPB) OTSN2IPY ANFB_HUMAN Increases Expression [39]
Homeobox protein Hox-B8 (HOXB8) OTKHOD17 HXB8_HUMAN Decreases Expression [39]
Homeobox protein Hox-B9 (HOXB9) OTMVHQOU HXB9_HUMAN Increases Expression [39]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Decreases Expression [39]
Complement receptor type 1 (CR1) OTODWRW4 CR1_HUMAN Decreases Expression [39]
Large ribosomal subunit protein eL33 (RPL35A) OTDDJUWF RL35A_HUMAN Increases Expression [39]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Decreases Expression [39]
Nucleolin (NCL) OTBXPKMP NUCL_HUMAN Decreases Expression [39]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) OT2D9DOV TNR1A_HUMAN Decreases Expression [39]
C-X-C motif chemokine 2 (CXCL2) OTEJCYMY CXCL2_HUMAN Decreases Expression [39]
C-X-C motif chemokine 3 (CXCL3) OTSL94KH CXCL3_HUMAN Decreases Expression [39]
Tryptase beta-2 (TPSB2) OTN769MT TRYB2_HUMAN Increases Expression [39]
Interferon-induced GTP-binding protein Mx2 (MX2) OT05NF37 MX2_HUMAN Decreases Expression [39]
B-cell lymphoma 3 protein (BCL3) OT1M5B95 BCL3_HUMAN Decreases Expression [39]
Serine/threonine-protein kinase MAK (MAK) OTEU2G41 MAK_HUMAN Decreases Expression [39]
Phosphatidylcholine translocator ABCB4 (ABCB4) OTE6PY83 MDR3_HUMAN Increases Expression [39]
Synaptotagmin-1 (SYT1) OTVTPOI6 SYT1_HUMAN Increases Expression [39]
Trifunctional purine biosynthetic protein adenosine-3 (GART) OT01JWJB PUR2_HUMAN Decreases Expression [39]
Tenascin-X (TNXB) OTVBWAV5 TENX_HUMAN Increases Expression [39]
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Increases Expression [39]
Cytochrome P450 7A1 (CYP7A1) OT8Z5KLD CP7A1_HUMAN Decreases Expression [39]
Insulin-like growth factor-binding protein 4 (IGFBP4) OT2HZRBD IBP4_HUMAN Decreases Expression [39]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) OTHJQ1DZ RPB1_HUMAN Increases Expression [39]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Increases Expression [39]
Polypyrimidine tract-binding protein 1 (PTBP1) OT2OBJUK PTBP1_HUMAN Decreases Expression [39]
Aryl hydrocarbon receptor nuclear translocator (ARNT) OTMSIEZY ARNT_HUMAN Decreases Expression [39]
Grancalcin (GCA) OTAJ7ZHG GRAN_HUMAN Decreases Expression [39]
Retinoblastoma-like protein 1 (RBL1) OTDEBFYC RBL1_HUMAN Increases Expression [39]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Decreases Expression [39]
Lens fiber major intrinsic protein (MIP) OTEBLU3E MIP_HUMAN Increases Expression [39]
Homeobox protein Hox-A11 (HOXA11) OT42C4HF HXA11_HUMAN Decreases Expression [39]
Gamma-aminobutyric acid receptor subunit alpha-5 (GABRA5) OTBIKWQT GBRA5_HUMAN Decreases Expression [39]
Homeobox protein OTX1 (OTX1) OTRGSGH9 OTX1_HUMAN Decreases Expression [39]
G protein-coupled receptor kinase 4 (GRK4) OTUU8V2S GRK4_HUMAN Increases Expression [39]
Desmoglein-3 (DSG3) OTGO4GEY DSG3_HUMAN Increases Expression [39]
Catenin alpha-1 (CTNNA1) OTFC725Z CTNA1_HUMAN Decreases Expression [39]
Merlin (NF2) OT6E5ACG MERL_HUMAN Decreases Expression [39]
Mu-type opioid receptor (OPRM1) OT16AAT8 OPRM_HUMAN Increases Expression [39]
Alpha-adducin (ADD1) OTTF68DC ADDA_HUMAN Increases Expression [39]
RNA-binding protein FUS (FUS) OTPPNGQO FUS_HUMAN Decreases Expression [39]
Choline kinase alpha (CHKA) OT7FVO3Z CHKA_HUMAN Decreases Expression [39]
Vitamin K-dependent gamma-carboxylase (GGCX) OTE0FNAP VKGC_HUMAN Decreases Expression [39]
DNA-binding protein SMUBP-2 (IGHMBP2) OTAZFPF5 SMBP2_HUMAN Decreases Expression [39]
Large ribosomal subunit protein uL3 (RPL3) OTX6VXLB RL3_HUMAN Decreases Expression [39]
Chymotrypsin-like protease CTRL-1 (CTRL) OTB6NA5O CTRL_HUMAN Decreases Expression [39]
Pre-B-cell leukemia transcription factor 2 (PBX2) OTEBYCAW PBX2_HUMAN Decreases Expression [39]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Decreases Expression [39]
Chloride anion exchanger (SLC26A3) OTBNK2U2 S26A3_HUMAN Decreases Expression [39]
Extracellular calcium-sensing receptor (CASR) OT2PEJDO CASR_HUMAN Decreases Expression [39]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8) OTOZTA1F M3K8_HUMAN Decreases Expression [39]
C-C chemokine receptor type 2 (CCR2) OTQ7T10J CCR2_HUMAN Decreases Expression [39]
Signal transducer and activator of transcription 6 (STAT6) OTCKMP49 STAT6_HUMAN Decreases Expression [39]
Caspase-2 (CASP2) OTUDYSPP CASP2_HUMAN Increases Expression [39]
Neuronal vesicle trafficking-associated protein 1 (NSG1) OTRIMA50 NSG1_HUMAN Increases Expression [39]
Glucagon-like peptide 1 receptor (GLP1R) OTMB1WEY GLP1R_HUMAN Decreases Expression [39]
ETS translocation variant 4 (ETV4) OT8C98UZ ETV4_HUMAN Increases Expression [39]
Melanoma-associated antigen 12 (MAGEA12) OT8ULELL MAGAC_HUMAN Increases Expression [39]
Ran-specific GTPase-activating protein (RANBP1) OTQE226K RANG_HUMAN Decreases Expression [39]
Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2) OTX31RLZ KI2S2_HUMAN Decreases Expression [39]
G-protein coupled receptor 4 (GPR4) OTIBF32I GPR4_HUMAN Decreases Expression [39]
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) OTI2OREX MP2K3_HUMAN Decreases Expression [39]
Olfactory marker protein (OMP) OT7JH0DY OMP_HUMAN Decreases Expression [39]
Interferon alpha/beta receptor 2 (IFNAR2) OTBIRNIJ INAR2_HUMAN Decreases Expression [39]
Serpin B4 (SERPINB4) OT88LHZ8 SPB4_HUMAN Increases Expression [39]
Neuropeptide Y receptor type 2 (NPY2R) OTEWQJ6B NPY2R_HUMAN Decreases Expression [39]
Melatonin receptor type 1B (MTNR1B) OT6VFHX9 MTR1B_HUMAN Increases Expression [39]
Beta-arrestin-1 (ARRB1) OT2NJS37 ARRB1_HUMAN Decreases Expression [39]
Transmembrane ascorbate-dependent reductase CYB561 (CYB561) OT61GMNV CY561_HUMAN Increases Expression [39]
Cysteine--tRNA ligase, cytoplasmic (CARS1) OTOUZF6O SYCC_HUMAN Decreases Expression [39]
Proteasome subunit beta type-2 (PSMB2) OTX0UG5W PSB2_HUMAN Decreases Expression [39]
Regulator of G-protein signaling 7 (RGS7) OTDQA90X RGS7_HUMAN Increases Expression [39]
Serpin B9 (SERPINB9) OTJ811IF SPB9_HUMAN Decreases Expression [39]
Matrix metalloproteinase-16 (MMP16) OTSFQ2BJ MMP16_HUMAN Increases Expression [39]
Arylsulfatase D (ARSD) OTAHW9M8 ARSD_HUMAN Decreases Expression [39]
Ataxin-1 (ATXN1) OTQF0HNR ATX1_HUMAN Increases Expression [39]
RNA polymerase II elongation factor ELL (ELL) OTCBN5LF ELL_HUMAN Decreases Expression [39]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Decreases Expression [39]
FAD-linked sulfhydryl oxidase ALR (GFER) OTVK43OK ALR_HUMAN Decreases Expression [39]
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1) OT536PE7 SCOT1_HUMAN Decreases Expression [39]
Period circadian protein homolog 3 (PER3) OTVKYVJA PER3_HUMAN Increases Expression [39]
Sestrin-3 (SESN3) OTJRY1Y5 SESN3_HUMAN Increases Expression [39]
Taste receptor type 2 member 50 (TAS2R50) OTPRMVZW T2R50_HUMAN Decreases Expression [39]
FXYD domain-containing ion transport regulator 4 (FXYD4) OT06IH3H FXYD4_HUMAN Increases Expression [39]
Eukaryotic initiation factor 4A-I (EIF4A1) OTMTBX6N IF4A1_HUMAN Decreases Expression [39]
Ras-related protein Rap-2b (RAP2B) OTD2NDQP RAP2B_HUMAN Decreases Expression [39]
LIM domain transcription factor LMO4 (LMO4) OT5NDCT9 LMO4_HUMAN Increases Expression [39]
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) OT24GMCM PP2AB_HUMAN Decreases Expression [39]
Small ribosomal subunit protein eS6 (RPS6) OTT4D1LN RS6_HUMAN Decreases Expression [39]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Decreases Expression [39]
Peptidyl-prolyl cis-trans isomerase A (PPIA) OTHJMWQQ PPIA_HUMAN Decreases Expression [39]
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) OT6285L4 FKB1A_HUMAN Decreases Expression [39]
Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA) OT2CEYTT SHPS1_HUMAN Increases Expression [39]
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM8) OT24S8YN ADAM8_HUMAN Decreases Expression [39]
SRSF protein kinase 2 (SRPK2) OTFFKMU1 SRPK2_HUMAN Increases Expression [39]
UDP-galactose translocator (SLC35A2) OTQOTOWZ S35A2_HUMAN Decreases Expression [39]
mRNA export factor RAE1 (RAE1) OT54OKC3 RAE1L_HUMAN Increases Expression [39]
Enhancer of rudimentary homolog (ERH) OTJDWX99 ERH_HUMAN Decreases Expression [39]
Histone H3.3 (H3-3B) OT9XHQ3C H33_HUMAN Decreases Expression [39]
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2) OT6HTSJT PGBM_HUMAN Increases Expression [39]
Low-density lipoprotein receptor-related protein 2 (LRP2) OTZ6W681 LRP2_HUMAN Increases Expression [39]
Phosphatidylinositol transfer protein alpha isoform (PITPNA) OTTWC00K PIPNA_HUMAN Decreases Expression [39]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Increases Expression [39]
Forkhead box protein K2 (FOXK2) OTFXDZ3R FOXK2_HUMAN Increases Expression [39]
High affinity immunoglobulin epsilon receptor subunit beta (MS4A2) OTMCAS2D FCERB_HUMAN Increases Expression [39]
Interferon-induced transmembrane protein 3 (IFITM3) OT2QP8D3 IFM3_HUMAN Decreases Expression [39]
Interferon-induced transmembrane protein 2 (IFITM2) OTAT6TI6 IFM2_HUMAN Decreases Expression [39]
POU domain, class 4, transcription factor 1 (POU4F1) OTMHYGWQ PO4F1_HUMAN Decreases Expression [39]
Collagen alpha-3(IV) chain (COL4A3) OT6SB8X5 CO4A3_HUMAN Increases Expression [39]
Amyloid-beta A4 precursor protein-binding family A member 1 (APBA1) OTUH9JPD APBA1_HUMAN Increases Expression [39]
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) OTPV1D60 FKBP4_HUMAN Decreases Expression [39]
Mucin-2 (MUC2) OT3X4QVX MUC2_HUMAN Decreases Expression [39]
cAMP-responsive element modulator (CREM) OTJIJ5AL CREM_HUMAN Decreases Expression [39]
Tyrosine-protein phosphatase non-receptor type 12 (PTPN12) OT5WA666 PTN12_HUMAN Increases Expression [39]
Early growth response protein 4 (EGR4) OT4R3ECK EGR4_HUMAN Decreases Expression [39]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Decreases Expression [39]
Sulfotransferase 2A1 (SULT2A1) OT0ISKQ4 ST2A1_HUMAN Decreases Expression [39]
Rho GTPase-activating protein 1 (ARHGAP1) OT0H2ZBZ RHG01_HUMAN Increases Expression [39]
3',5'-cyclic-AMP phosphodiesterase 4C (PDE4C) OTI8VMHZ PDE4C_HUMAN Increases Expression [39]
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (MGAT5) OTU4DD4G MGT5A_HUMAN Increases Expression [39]
Uncharacterized protein C17orf67 (C17ORF67) OTCL5EE8 CQ067_HUMAN Decreases Expression [39]
Thyrotroph embryonic factor (TEF) OTY3LAD9 TEF_HUMAN Increases Expression [39]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1) OTFCO8QX SIA4A_HUMAN Decreases Expression [39]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1) OTNYXOZO KCMA1_HUMAN Increases Expression [39]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) OT2LP7LJ SNF5_HUMAN Increases Expression [39]
Glutamate receptor ionotropic, NMDA 2A (GRIN2A) OTTP0KN8 NMDE1_HUMAN Increases Expression [39]
Receptor-type tyrosine-protein phosphatase eta (PTPRJ) OT10OKOF PTPRJ_HUMAN Increases Expression [39]
Forkhead box protein C1 (FOXC1) OTOWZGYO FOXC1_HUMAN Decreases Expression [39]
Glutamate receptor ionotropic, kainate 3 (GRIK3) OTX6K345 GRIK3_HUMAN Decreases Expression [39]
Rho GTPase-activating protein 5 (ARHGAP5) OTOQELUN RHG05_HUMAN Increases Expression [39]
PR domain zinc finger protein 2 (PRDM2) OT8L7CGX PRDM2_HUMAN Decreases Expression [39]
Lymphocyte cytosolic protein 2 (LCP2) OT57KE22 LCP2_HUMAN Decreases Expression [39]
S-methyl-5'-thioadenosine phosphorylase (MTAP) OTOWN2K9 MTAP_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase CBL-B (CBLB) OTPLRER9 CBLB_HUMAN Decreases Expression [39]
DNA excision repair protein ERCC-8 (ERCC8) OT0T4WKI ERCC8_HUMAN Increases Expression [39]
Signaling lymphocytic activation molecule (SLAMF1) OTBTT3ZQ SLAF1_HUMAN Decreases Expression [39]
Limbic system-associated membrane protein (LSAMP) OTYXVQX2 LSAMP_HUMAN Decreases Expression [39]
GRB2-associated-binding protein 1 (GAB1) OTQKE6V4 GAB1_HUMAN Increases Expression [39]
Histone deacetylase 1 (HDAC1) OTQDNOXZ HDAC1_HUMAN Decreases Expression [39]
Interferon regulatory factor 5 (IRF5) OT8SIIAP IRF5_HUMAN Increases Expression [39]
Nucleic acid dioxygenase ALKBH1 (ALKBH1) OTADGU5D ALKB1_HUMAN Affects Expression [39]
Sodium/potassium-transporting ATPase subunit alpha-4 (ATP1A4) OT9PLMBH AT1A4_HUMAN Increases Expression [39]
Integrin alpha-9 (ITGA9) OTHN1IKA ITA9_HUMAN Decreases Expression [39]
Plakophilin-1 (PKP1) OT9HSQ8F PKP1_HUMAN Decreases Expression [39]
Myelin-associated oligodendrocyte basic protein (MOBP) OTHJT5CX MOBP_HUMAN Decreases Expression [39]
Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) OT6KFNMS CAC1C_HUMAN Decreases Expression [39]
Dihydropyrimidinase-related protein 3 (DPYSL3) OTINJV20 DPYL3_HUMAN Increases Expression [39]
Elongin-A (ELOA) OTOQTF5K ELOA1_HUMAN Increases Expression [39]
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) OT8RPSOC FKBP8_HUMAN Decreases Expression [39]
ATP-dependent RNA helicase DHX8 (DHX8) OT97S0IH DHX8_HUMAN Decreases Expression [39]
Nuclear receptor coactivator 6 (NCOA6) OTOMIGTV NCOA6_HUMAN Decreases Expression [39]
Raftlin (RFTN1) OT8875JE RFTN1_HUMAN Increases Expression [39]
Chromobox protein homolog 2 (CBX2) OTOQ5WS4 CBX2_HUMAN Increases Expression [39]
Nuclear factor 1 X-type (NFIX) OT1DPZAE NFIX_HUMAN Increases Expression [39]
Importin subunit beta-1 (KPNB1) OTBT2HFL IMB1_HUMAN Increases Expression [39]
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) OT5K42IK GAPD1_HUMAN Increases Expression [39]
MAD2L1-binding protein (MAD2L1BP) OT2O2IUJ MD2BP_HUMAN Decreases Expression [39]
Rab GTPase-binding effector protein 1 (RABEP1) OTQROTGT RABE1_HUMAN Increases Expression [39]
SH2 domain-containing adapter protein B (SHB) OTF2HSC0 SHB_HUMAN Decreases Expression [39]
Ficolin-2 (FCN2) OTTHJBKZ FCN2_HUMAN Increases Expression [39]
Transcription elongation factor A protein 2 (TCEA2) OT1OS9TY TCEA2_HUMAN Increases Expression [39]
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF2) OTRHB9SR NHRF2_HUMAN Decreases Expression [39]
Olfactory receptor 1C1 (OR1C1) OT9WTEX5 OR1C1_HUMAN Decreases Expression [39]
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) OTBOSJHO TRADD_HUMAN Increases Expression [39]
Tryptase alpha/beta-1 (TPSAB1) OTJYI4WV TRYB1_HUMAN Increases Expression [39]
Leukotriene B4 receptor 1 (LTB4R) OT3SRH4H LT4R1_HUMAN Decreases Expression [39]
CCAAT/enhancer-binding protein epsilon (CEBPE) OTKZA25M CEBPE_HUMAN Decreases Expression [39]
Ras-related protein Rab-30 (RAB30) OTW49G8B RAB30_HUMAN Increases Expression [39]
Acid-sensing ion channel 2 (ASIC2) OTIVFS3H ASIC2_HUMAN Increases Expression [39]
Myelin-oligodendrocyte glycoprotein (MOG) OTYNB7Y5 MOG_HUMAN Decreases Expression [39]
Tyrosine-protein phosphatase non-receptor type 21 (PTPN21) OTQBZWSE PTN21_HUMAN Increases Expression [39]
Dual oxidase maturation factor 2 (DUOXA2) OT7AZBZJ DOXA2_HUMAN Decreases Expression [39]
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) OTJ6JTGT HNRL2_HUMAN Increases Expression [39]
R-spondin-4 (RSPO4) OTFX5N3G RSPO4_HUMAN Decreases Expression [39]
ATP-binding cassette sub-family B member 5 (ABCB5) OT8AKP1J ABCB5_HUMAN Increases Expression [39]
Neuroblastoma breakpoint family member 1 (NBPF1) OTAZ55UQ NBPF1_HUMAN Increases Expression [39]
TBC1 domain family member 25 (TBC1D25) OT11OABF TBC25_HUMAN Decreases Expression [39]
Transmembrane protein 176B (TMEM176B) OTEGF2BV T176B_HUMAN Decreases Expression [39]
C2 domain-containing protein 3 (C2CD3) OTC52E7V C2CD3_HUMAN Increases Expression [39]
tRNA-queuosine alpha-mannosyltransferase (GTDC1) OT8OBXKK QTMAN_HUMAN Increases Expression [39]
Coiled-coil domain-containing protein 152 (CCDC152) OTJQTQXC CC152_HUMAN Increases Expression [39]
Coiled-coil domain-containing protein 40 (CCDC40) OTFHEUUN CCD40_HUMAN Decreases Expression [39]
Minichromosome maintenance domain-containing protein 2 (MCMDC2) OTTG0EQU MCMD2_HUMAN Decreases Expression [39]
Synaptotagmin-like protein 3 (SYTL3) OT6TPBA9 SYTL3_HUMAN Increases Expression [39]
Protein lin-52 homolog (LIN52) OT14OQ1C LIN52_HUMAN Increases Expression [39]
Seizure protein 6 homolog (SEZ6) OTCD8K5D SEZ6_HUMAN Decreases Expression [39]
Transmembrane 4 L6 family member 20 (TM4SF20) OTNXU9QW T4S20_HUMAN Decreases Expression [39]
HCLS1-binding protein 3 (HS1BP3) OT5NSZJ1 H1BP3_HUMAN Decreases Expression [39]
Germinal center-associated signaling and motility-like protein (GCSAML) OTYWDOA6 GSAML_HUMAN Increases Expression [39]
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 (SOHLH1) OT3RBLSK SOLH1_HUMAN Decreases Expression [39]
Intracellular hyaluronan-binding protein 4 (HABP4) OTU223PA HABP4_HUMAN Increases Expression [39]
Coiled-coil domain-containing protein 158 (CCDC158) OTT3RXZN CD158_HUMAN Decreases Expression [39]
RNA-binding protein 26 (RBM26) OTG4C53Y RBM26_HUMAN Decreases Expression [39]
Roquin-1 (RC3H1) OTCU6CYA RC3H1_HUMAN Decreases Expression [39]
Radial spoke head protein 4 homolog A (RSPH4A) OTNDPGEE RSH4A_HUMAN Decreases Expression [39]
Four and a half LIM domains protein 5 (FHL5) OT6C00Z1 FHL5_HUMAN Decreases Expression [39]
Protein PRR14L (PRR14L) OT290EDE PR14L_HUMAN Increases Expression [39]
Centrosome-associated protein 350 (CEP350) OT5Q3AEA CE350_HUMAN Increases Expression [39]
Divergent protein kinase domain 1B (DIPK1B) OTSPU5O5 DIK1B_HUMAN Increases Expression [39]
OTU domain-containing protein 1 (OTUD1) OTE6O5XB OTUD1_HUMAN Decreases Expression [39]
DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2) OTLEF5TY DC122_HUMAN Increases Expression [39]
Interleukin-23 receptor (IL23R) OTT6L7U8 IL23R_HUMAN Decreases Expression [39]
Muscular LMNA-interacting protein (MLIP) OTMT7AII MLIP_HUMAN Increases Expression [39]
Ankyrin repeat domain-containing protein 34A (ANKRD34A) OTI00ROL AN34A_HUMAN Decreases Expression [39]
Multiple C2 and transmembrane domain-containing protein 2 (MCTP2) OTFMZ8I2 MCTP2_HUMAN Decreases Expression [39]
General transcription factor II-I repeat domain-containing protein 2B (GTF2IRD2B) OTO0L3A2 GTD2B_HUMAN Increases Expression [39]
Tyrosine-protein kinase STYK1 (STYK1) OT61CSU7 STYK1_HUMAN Decreases Expression [39]
Kelch-like protein 10 (KLHL10) OTB41MP9 KLH10_HUMAN Increases Expression [39]
Proline-rich protein 5-like (PRR5L) OTQ1Z0OU PRR5L_HUMAN Decreases Expression [39]
RPA-related protein RADX (RADX) OTKV8BMJ RADX_HUMAN Increases Expression [39]
Glutamate-rich protein 5 (ERICH5) OTQEY1SQ ERIC5_HUMAN Increases Expression [39]
Ankyrin repeat domain-containing protein 16 (ANKRD16) OTZD4JUO ANR16_HUMAN Decreases Expression [39]
MTOR-associated protein MEAK7 (MEAK7) OT9A8JSO MEAK7_HUMAN Decreases Expression [39]
E3 ubiquitin-protein ligase RFWD3 (RFWD3) OTDUULBQ RFWD3_HUMAN Decreases Expression [39]
F-box only protein 38 (FBXO38) OTSZ3768 FBX38_HUMAN Decreases Expression [39]
Consortin (CNST) OTOUCB98 CNST_HUMAN Increases Expression [39]
Docking protein 6 (DOK6) OTX55OIF DOK6_HUMAN Increases Expression [39]
Type-1 angiotensin II receptor-associated protein (AGTRAP) OT02N7LD ATRAP_HUMAN Decreases Expression [39]
Coiled-coil domain-containing protein 171 (CCDC171) OT9NL2D9 CC171_HUMAN Increases Expression [39]
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L) OTV01EFP C1TM_HUMAN Increases Expression [39]
Transmembrane protein 107 (TMEM107) OT9RMLBJ TM107_HUMAN Decreases Expression [39]
C-type lectin domain family 4 member G (CLEC4G) OTUGTR0H CLC4G_HUMAN Decreases Expression [39]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (TPTE2) OTR3K733 TPTE2_HUMAN Increases Expression [39]
Sulfhydryl oxidase 2 (QSOX2) OTMLKYFP QSOX2_HUMAN Decreases Expression [39]
Patched domain-containing protein 4 (PTCHD4) OTGJ8NRP PTHD4_HUMAN Increases Expression [39]
Cyclic AMP-responsive element-binding protein 3-like protein 2 (CREB3L2) OT09MHV0 CR3L2_HUMAN Increases Expression [39]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2) OTYT1J6J PREX2_HUMAN Decreases Expression [39]
Protein FRA10AC1 (FRA10AC1) OT730MMV F10C1_HUMAN Increases Expression [39]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L) OTSP1W0F MD13L_HUMAN Increases Expression [39]
Immunoglobulin-like domain-containing receptor 2 (ILDR2) OTNNK3VC ILDR2_HUMAN Increases Expression [39]
GRB2-associated and regulator of MAPK protein 2 (GAREM2) OTQNQAC7 GARE2_HUMAN Increases Expression [39]
Carbohydrate sulfotransferase 15 (CHST15) OTNTM2SP CHSTF_HUMAN Decreases Expression [39]
STE20-related kinase adapter protein alpha (STRADA) OTG1Z6TY STRAA_HUMAN Decreases Expression [39]
#NAME? OTD229X7 MICA3_HUMAN Increases Expression [39]
Aprataxin (APTX) OTPAS5G8 APTX_HUMAN Decreases Expression [39]
Endoplasmic reticulum metallopeptidase 1 (ERMP1) OT9CIEO2 ERMP1_HUMAN Decreases Expression [39]
Nucleoporin p54 (NUP54) OTHOIRMG NUP54_HUMAN Decreases Expression [39]
Keratin, type I cytoskeletal 25 (KRT25) OT4JMRN6 K1C25_HUMAN Increases Expression [39]
Transmembrane channel-like protein 6 (TMC6) OTKH50J4 TMC6_HUMAN Decreases Expression [39]
Cytoplasmic polyadenylation element-binding protein 2 (CPEB2) OTKES4YR CPEB2_HUMAN Decreases Expression [39]
FERM domain-containing protein 5 (FRMD5) OTC73XJK FRMD5_HUMAN Increases Expression [39]
Beta-defensin 132 (DEFB132) OT5SRTW1 DB132_HUMAN Increases Expression [39]
Cytokine-dependent hematopoietic cell linker (CLNK) OTOWK51S CLNK_HUMAN Decreases Expression [39]
Protein polybromo-1 (PBRM1) OT39WUR9 PB1_HUMAN Increases Expression [39]
CUB and zona pellucida-like domain-containing protein 1 (CUZD1) OTDQJVZ8 CUZD1_HUMAN Increases Expression [39]
Organic solute transporter subunit alpha (SLC51A) OTDJRZ0P OSTA_HUMAN Increases Expression [39]
Zinc finger protein castor homolog 1 (CASZ1) OTWJ2OR8 CASZ1_HUMAN Increases Expression [39]
Liprin-beta-1 (PPFIBP1) OTRA2S7B LIPB1_HUMAN Increases Expression [39]
Fibrocystin-L (PKHD1L1) OTREFCAA PKHL1_HUMAN Increases Expression [39]
Protein NLRC5 (NLRC5) OTY8X6MC NLRC5_HUMAN Decreases Expression [39]
Vasculin (GPBP1) OTUXR2GD GPBP1_HUMAN Increases Expression [39]
Ral GTPase-activating protein subunit beta (RALGAPB) OTY8CGA3 RLGPB_HUMAN Increases Expression [39]
Diacylglycerol kinase eta (DGKH) OTYNPJ4B DGKH_HUMAN Decreases Expression [39]
Probable guanine nucleotide exchange factor MCF2L2 (MCF2L2) OTOGFMIH MF2L2_HUMAN Decreases Expression [39]
Ras-related protein Rab-43 (RAB43) OTVCSILI RAB43_HUMAN Decreases Expression [39]
NudC domain-containing protein 3 (NUDCD3) OT2WYBNC NUDC3_HUMAN Decreases Expression [39]
Somatomedin-B and thrombospondin type-1 domain-containing protein (SBSPON) OTBHAW5K SBSPO_HUMAN Increases Expression [39]
Kinase suppressor of Ras 1 (KSR1) OT9GUVLI KSR1_HUMAN Decreases Expression [39]
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 (NKAIN4) OT91HOEP NKAI4_HUMAN Decreases Expression [39]
Sphingosine-1-phosphate transporter SPNS2 (SPNS2) OTPODAPU SPNS2_HUMAN Decreases Expression [39]
FAD-dependent oxidoreductase domain-containing protein 2 (FOXRED2) OTSJOZ3O FXRD2_HUMAN Decreases Expression [39]
PHD finger protein 6 (PHF6) OT8DXI40 PHF6_HUMAN Increases Expression [39]
Calcium homeostasis endoplasmic reticulum protein (CHERP) OTJL4OB3 CHERP_HUMAN Decreases Expression [39]
GTP-binding protein REM 2 (REM2) OT0RTOI8 REM2_HUMAN Decreases Expression [39]
Cilia- and flagella-associated protein 46 (CFAP46) OTRZZHB9 CFA46_HUMAN Increases Expression [39]
Rhotekin-2 (RTKN2) OTV2AXQM RTKN2_HUMAN Increases Expression [39]
Heparan-sulfate 6-O-sulfotransferase 3 (HS6ST3) OTTW9PDL H6ST3_HUMAN Decreases Expression [39]
Leucine-rich repeat LGI family member 3 (LGI3) OT0CZ85H LGI3_HUMAN Increases Expression [39]
Protein SYS1 homolog (SYS1) OTTVS1LN SYS1_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase pellino homolog 3 (PELI3) OTCBUSKJ PELI3_HUMAN Increases Expression [39]
Protein FAM43A (FAM43A) OT5RPQRE FA43A_HUMAN Increases Expression [39]
Leucine-rich repeat-containing protein 25 (LRRC25) OTCKAZA5 LRC25_HUMAN Decreases Expression [39]
Chemokine-like protein TAFA-2 (TAFA2) OTU6WP6J TAFA2_HUMAN Decreases Expression [39]
Follistatin-related protein 5 (FSTL5) OT18C29S FSTL5_HUMAN Increases Expression [39]
Kinesin-like protein KIF2B (KIF2B) OTLPAX4N KIF2B_HUMAN Increases Expression [39]
T-complex protein 11-like protein 2 (TCP11L2) OTTIZO7B T11L2_HUMAN Increases Expression [39]
Prolyl 3-hydroxylase OGFOD1 (OGFOD1) OTTUQ5O3 OGFD1_HUMAN Increases Expression [39]
Ceramide synthase 5 (CERS5) OT5A2DNI CERS5_HUMAN Increases Expression [39]
Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) OTBNQCOS LIRA3_HUMAN Decreases Expression [39]
IQ domain-containing protein F1 (IQCF1) OTXFEQ37 IQCF1_HUMAN Decreases Expression [39]
Stress-associated endoplasmic reticulum protein 2 (SERP2) OT5GA6JZ SERP2_HUMAN Increases Expression [39]
Leucine-rich repeat-containing protein 17 (LRRC17) OT3NZSX3 LRC17_HUMAN Increases Expression [39]
ER membrane protein complex subunit 1 (EMC1) OTYAH4LX EMC1_HUMAN Decreases Expression [39]
Androglobin (ADGB) OT1TM9DT ADGB_HUMAN Decreases Expression [39]
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (ANKRD44) OTUI0WOO ANR44_HUMAN Decreases Expression [39]
Coiled-coil domain-containing protein 71L (CCDC71L) OT7ECVUW CC71L_HUMAN Decreases Expression [39]
Tetratricopeptide repeat protein 29 (TTC29) OT37KCUL TTC29_HUMAN Increases Expression [39]
Fanconi anemia group B protein (FANCB) OTMZTXB5 FANCB_HUMAN Increases Expression [39]
Hemicentin-2 (HMCN2) OTJK9CGG HMCN2_HUMAN Increases Expression [39]
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) OTLUM9L7 PK3C3_HUMAN Increases Expression [39]
Microcephalin (MCPH1) OTYT3TT5 MCPH1_HUMAN Increases Expression [39]
Methylcytosine dioxygenase TET1 (TET1) OTZDHT1D TET1_HUMAN Increases Expression [39]
Telomere repeats-binding bouquet formation protein 2 (TERB2) OTUJDOF8 TERB2_HUMAN Increases Expression [39]
Checkpoint protein HUS1B (HUS1B) OT3VFQWS HUS1B_HUMAN Decreases Expression [39]
Stomatin-like protein 3 (STOML3) OTLQGALK STML3_HUMAN Increases Expression [39]
Protein odd-skipped-related 1 (OSR1) OTB19LEQ OSR1_HUMAN Increases Expression [39]
Ras and Rab interactor 3 (RIN3) OT5Z6F8O RIN3_HUMAN Decreases Expression [39]
Piwi-like protein 2 (PIWIL2) OT1PXQIF PIWL2_HUMAN Decreases Expression [39]
Glutamate receptor ionotropic, NMDA 3A (GRIN3A) OTQS9GYY NMD3A_HUMAN Increases Expression [39]
Mirror-image polydactyly gene 1 protein (MIPOL1) OTLPN3D0 MIPO1_HUMAN Increases Expression [39]
Chromodomain-helicase-DNA-binding protein 6 (CHD6) OTEHW1U2 CHD6_HUMAN Increases Expression [39]
Protocadherin Fat 3 (FAT3) OT3C6H8W FAT3_HUMAN Decreases Expression [39]
GPI ethanolamine phosphate transferase 3 (PIGO) OTGDOBO1 PIGO_HUMAN Decreases Expression [39]
Guanine nucleotide exchange protein SMCR8 (SMCR8) OT52BQH4 SMCR8_HUMAN Decreases Expression [39]
Partitioning defective 3 homolog B (PARD3B) OTGZ43YI PAR3L_HUMAN Increases Expression [39]
SH3 domain and tetratricopeptide repeat-containing protein 2 (SH3TC2) OTJ6XY2A S3TC2_HUMAN Increases Expression [39]
F-box only protein 41 (FBXO41) OT5MC4TZ FBX41_HUMAN Increases Expression [39]
Protein prune homolog 2 (PRUNE2) OTGW2974 PRUN2_HUMAN Increases Expression [39]
Protein POF1B (POF1B) OTFWNK8G POF1B_HUMAN Decreases Expression [39]
GTPase IMAP family member 1 (GIMAP1) OT7AJ1TT GIMA1_HUMAN Decreases Expression [39]
Palladin (PALLD) OTZ2MUJZ PALLD_HUMAN Increases Expression [39]
RUN and FYVE domain-containing protein 2 (RUFY2) OTT9C6SM RUFY2_HUMAN Increases Expression [39]
Stonin-2 (STON2) OT01JHHE STON2_HUMAN Increases Expression [39]
Connector enhancer of kinase suppressor of ras 2 (CNKSR2) OTAGERJ2 CNKR2_HUMAN Increases Expression [39]
Voltage-dependent calcium channel gamma-8 subunit (CACNG8) OTP6227G CCG8_HUMAN Increases Expression [39]
Cationic amino acid transporter 3 (SLC7A3) OTKEFAHV CTR3_HUMAN Decreases Expression [39]
Transmembrane O-methyltransferase (LRTOMT) OTMLESUJ TOMT_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase rififylin (RFFL) OT85MGDH RFFL_HUMAN Increases Expression [39]
Alpha-2,8-sialyltransferase 8B (ST8SIA2) OTRBBBD8 SIA8B_HUMAN Increases Expression [39]
Sorting nexin-19 (SNX19) OTGNS3HG SNX19_HUMAN Increases Expression [39]
Transmembrane protein 131 (TMEM131) OT72FBLT TM131_HUMAN Decreases Expression [39]
Stalled ribosome sensor GCN1 (GCN1) OTBFVD7Z GCN1_HUMAN Decreases Expression [39]
Centromere protein I (CENPI) OTWRIMZ3 CENPI_HUMAN Decreases Expression [39]
Caspase-10 (CASP10) OTE6J88E CASPA_HUMAN Decreases Expression [39]
Phosphatidate cytidylyltransferase 1 (CDS1) OT2F591M CDS1_HUMAN Increases Expression [39]
Endonuclease 8-like 2 (NEIL2) OTV6JEON NEIL2_HUMAN Decreases Expression [39]
Polyamine deacetylase HDAC10 (HDAC10) OTHCKKUQ HDA10_HUMAN Decreases Expression [39]
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) OT351FKB ERGI1_HUMAN Increases Expression [39]
Autophagy-related protein 2 homolog B (ATG2B) OT7FGFJ1 ATG2B_HUMAN Decreases Expression [39]
Pyrroline-5-carboxylate reductase 2 (PYCR2) OTS2HLGD P5CR2_HUMAN Decreases Expression [39]
FAS-associated factor 2 (FAF2) OTE8CE2E FAF2_HUMAN Increases Expression [39]
RalBP1-associated Eps domain-containing protein 1 (REPS1) OTX4ERRK REPS1_HUMAN Increases Expression [39]
U8 snoRNA-decapping enzyme (NUDT16) OTWSL9JQ NUD16_HUMAN Decreases Expression [39]
THAP domain-containing protein 11 (THAP11) OTEMWLZ0 THA11_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase CHFR (CHFR) OTRAD2TT CHFR_HUMAN Decreases Expression [39]
Small integral membrane protein 12 (SMIM12) OTMOQSL4 SIM12_HUMAN Decreases Expression [39]
UDP-N-acetylglucosamine transferase subunit ALG14 homolog (ALG14) OTBM7K28 ALG14_HUMAN Increases Expression [39]
OTU domain-containing protein 5 (OTUD5) OTMCR6JM OTUD5_HUMAN Decreases Expression [39]
Solute carrier family 25 member 44 (SLC25A44) OTHHPC3C S2544_HUMAN Decreases Expression [39]
Dedicator of cytokinesis protein 6 (DOCK6) OTPNUVLT DOCK6_HUMAN Increases Expression [39]
Kin of IRRE-like protein 1 (KIRREL1) OTOA7ON7 KIRR1_HUMAN Increases Expression [39]
Spatacsin (SPG11) OTZ7LJX4 SPTCS_HUMAN Affects Expression [39]
Protein SPMIP9 (SPMIP9) OT66UEFP SMIP9_HUMAN Decreases Expression [39]
Coiled-coil domain-containing protein 7 (CCDC7) OTNCL9JR CCDC7_HUMAN Increases Expression [39]
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1) OT5TS6P7 PCMD1_HUMAN Increases Expression [39]
Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST2) OT8A3H9Y H6ST2_HUMAN Increases Expression [39]
Transmembrane protein 74 (TMEM74) OT3IZBM0 TMM74_HUMAN Increases Expression [39]
2-oxoglutarate receptor 1 (OXGR1) OT2D4V93 OXGR1_HUMAN Increases Expression [39]
N-acetylneuraminate 9-O-acetyltransferase (CASD1) OT1YB54Z CASD1_HUMAN Decreases Expression [39]
AP-1 complex subunit sigma-3 (AP1S3) OTPCMV24 AP1S3_HUMAN Increases Expression [39]
BTB/POZ domain-containing protein 9 (BTBD9) OTWQ6GA3 BTBD9_HUMAN Decreases Expression [39]
Rho GTPase-activating protein 7 (DLC1) OTP8LMCR RHG07_HUMAN Increases Expression [39]
Sorting nexin-18 (SNX18) OT68KT3X SNX18_HUMAN Increases Expression [39]
Tribbles homolog 1 (TRIB1) OTPEO17G TRIB1_HUMAN Decreases Expression [39]
Ras-related protein Rab-40C (RAB40C) OTM2V2R0 RB40C_HUMAN Increases Expression [39]
Protein ABHD1 (ABHD1) OTY56U02 ABHD1_HUMAN Decreases Expression [39]
CDK5 regulatory subunit-associated protein 2 (CDK5RAP2) OTRKEVTY CK5P2_HUMAN Increases Expression [39]
Insulinoma-associated protein 2 (INSM2) OTNMQUZV INSM2_HUMAN Increases Expression [39]
Glutamate decarboxylase 1 (GAD1) OT52Z39J DCE1_HUMAN Decreases Expression [39]
M-phase phosphoprotein 6 (MPHOSPH6) OT6E2S48 MPH6_HUMAN Decreases Expression [39]
Max-binding protein MNT (MNT) OTPC4ANL MNT_HUMAN Decreases Expression [39]
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) OTVFRL8G TI17A_HUMAN Decreases Expression [39]
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) OTUKPFOK ROAA_HUMAN Decreases Expression [39]
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) OTT5JX1F LITAF_HUMAN Decreases Expression [39]
Noelin (OLFM1) OTOYPEWW NOE1_HUMAN Decreases Expression [39]
Spindlin-2A (SPIN2A) OT93VTU4 SPI2A_HUMAN Increases Expression [39]
Histone H2B type 1-M (H2BC14) OTSDZZZY H2B1M_HUMAN Decreases Expression [39]
Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B) OTT2ZGSR ATF6B_HUMAN Increases Expression [39]
Tyrosine-protein phosphatase non-receptor type 18 (PTPN18) OT0S09B3 PTN18_HUMAN Decreases Expression [39]
F-box-like/WD repeat-containing protein TBL1Y (TBL1Y) OTA0F7TM TBL1Y_HUMAN Decreases Expression [39]
Serine/threonine-protein phosphatase CPPED1 (CPPED1) OT88U8X5 CPPED_HUMAN Decreases Expression [39]
Suppressor of IKBKE 1 (SIKE1) OT5O11J0 SIKE1_HUMAN Increases Expression [39]
Mitochondrial nucleoid-associated protein 1 (MTNAP1) OT8FB2F8 CQ080_HUMAN Increases Expression [39]
Trichoplein keratin filament-binding protein (TCHP) OTVDMHSY TCHP_HUMAN Decreases Expression [39]
Immediate early response gene 2 protein (IER2) OT5OY8BO IER2_HUMAN Decreases Expression [39]
Protein misato homolog 1 (MSTO1) OT37XCNP MSTO1_HUMAN Decreases Expression [39]
PHD finger protein 23 (PHF23) OTVF5VZC PHF23_HUMAN Decreases Expression [39]
Specifically androgen-regulated gene protein (C1ORF116) OTPYEXDM SARG_HUMAN Increases Expression [39]
DET1- and DDB1-associated protein 1 (DDA1) OTAZIAIH DDA1_HUMAN Increases Expression [39]
GTP-binding protein 2 (GTPBP2) OTOJ1KUA GTPB2_HUMAN Increases Expression [39]
Protein LSM14 homolog B (LSM14B) OTW646HP LS14B_HUMAN Increases Expression [39]
Transient receptor potential cation channel subfamily M member 6 (TRPM6) OTW7SPUV TRPM6_HUMAN Decreases Expression [39]
Protein amnionless (AMN) OTS1TJXG AMNLS_HUMAN Decreases Expression [39]
Complement factor H-related protein 5 (CFHR5) OT7BMOYE FHR5_HUMAN Decreases Expression [39]
Testis-expressed protein 12 (TEX12) OTXHQWTA TEX12_HUMAN Decreases Expression [39]
Calcium-binding protein 8 (CALN1) OTN2XE4T CABP8_HUMAN Increases Expression [39]
Cell adhesion molecule 1 (CADM1) OTRWG9QS CADM1_HUMAN Increases Expression [39]
Polymerase delta-interacting protein 3 (POLDIP3) OTTB5SV7 PDIP3_HUMAN Increases Expression [39]
Large ribosomal subunit protein uL4m (MRPL4) OT8AE74Y RM04_HUMAN Decreases Expression [39]
Serine/threonine-protein kinase 33 (STK33) OT98KLEL STK33_HUMAN Increases Expression [39]
FERM domain-containing protein 8 (FRMD8) OTTH5DUJ FRMD8_HUMAN Decreases Expression [39]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1) OTM3B3OA TBL1R_HUMAN Decreases Expression [39]
Group XIIA secretory phospholipase A2 (PLA2G12A) OTHHCQ17 PG12A_HUMAN Increases Expression [39]
Testicular spindle-associated protein SHCBP1L (SHCBP1L) OTYGG089 SHP1L_HUMAN Decreases Expression [39]
GREB1-like protein (GREB1L) OTZTY5KQ GRB1L_HUMAN Increases Expression [39]
E3 ubiquitin-protein ligase makorin-2 (MKRN2) OTDD1V3O MKRN2_HUMAN Increases Expression [39]
Large subunit GTPase 1 homolog (LSG1) OTDAXJ9L LSG1_HUMAN Decreases Expression [39]
NUAK family SNF1-like kinase 2 (NUAK2) OTUEZLO8 NUAK2_HUMAN Decreases Expression [39]
Oxysterol-binding protein-related protein 5 (OSBPL5) OTI1UJXT OSBL5_HUMAN Decreases Expression [39]
Nucleoporin-62 C-terminal-like protein (NUP62CL) OTEN1HET N62CL_HUMAN Increases Expression [39]
Oxysterol-binding protein-related protein 2 (OSBPL2) OTCK671N OSBL2_HUMAN Decreases Expression [39]
Ciliary microtubule inner protein 1 (CIMIP1) OTKOYVKF CMIP1_HUMAN Increases Expression [39]
Mediator of RNA polymerase II transcription subunit 28 (MED28) OTEDM1L5 MED28_HUMAN Decreases Expression [39]
EH domain-containing protein 4 (EHD4) OT7G5JTT EHD4_HUMAN Decreases Expression [39]
Translation initiation factor IF-3, mitochondrial (MTIF3) OTPQ7FPQ IF3M_HUMAN Increases Expression [39]
Kallikrein-15 (KLK15) OT7BVG17 KLK15_HUMAN Decreases Expression [39]
Chordin (CHRD) OTNM60Y1 CHRD_HUMAN Decreases Expression [39]
Sorting nexin-25 (SNX25) OT8JY8M1 SNX25_HUMAN Increases Expression [39]
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10) OT5HFZXU BACD3_HUMAN Decreases Expression [39]
Histamine H4 receptor (HRH4) OTBJO49O HRH4_HUMAN Decreases Expression [39]
Leucine-rich repeat neuronal protein 3 (LRRN3) OT7X0AA7 LRRN3_HUMAN Increases Expression [39]
Cystatin-9-like (CST9L) OT7GBIWW CST9L_HUMAN Increases Expression [39]
Cilia- and flagella-associated protein 68 (CFAP68) OTG4EK2P CFA68_HUMAN Decreases Expression [39]
tRNA (NSUN3) OTLBKU22 NSUN3_HUMAN Decreases Expression [39]
DENN domain-containing protein 2D (DENND2D) OTXEFJWM DEN2D_HUMAN Decreases Expression [39]
HAUS augmin-like complex subunit 4 (HAUS4) OTFIO49N HAUS4_HUMAN Decreases Expression [39]
PDZ domain-containing protein MAGIX (MAGIX) OT8EU651 MAGIX_HUMAN Increases Expression [39]
Tudor domain-containing protein 3 (TDRD3) OTG83E2C TDRD3_HUMAN Increases Expression [39]
Nuclear exosome regulator NRDE2 (NRDE2) OTJ1V33O NRDE2_HUMAN Increases Expression [39]
Proton-activated chloride channel (PACC1) OTKBS8CC PACC1_HUMAN Increases Expression [39]
Jupiter microtubule associated homolog 2 (JPT2) OTJGPA4T JUPI2_HUMAN Increases Expression [39]
Akirin-1 (AKIRIN1) OTINWTT9 AKIR1_HUMAN Decreases Expression [39]
DNA-directed RNA polymerase I subunit RPA2 (POLR1B) OTKREU8M RPA2_HUMAN Decreases Expression [39]
Pleckstrin homology domain-containing family A member 5 (PLEKHA5) OT2MNW8T PKHA5_HUMAN Increases Expression [39]
Claspin (CLSPN) OTZZXNDK CLSPN_HUMAN Increases Expression [39]
Dual specificity protein kinase CLK4 (CLK4) OTD38YJI CLK4_HUMAN Increases Expression [39]
Sp110 nuclear body protein (SP110) OTFW6WH7 SP110_HUMAN Decreases Expression [39]
POZ-, AT hook-, and zinc finger-containing protein 1 (PATZ1) OT0X9WGR PATZ1_HUMAN Decreases Expression [39]
Interleukin-21 receptor (IL21R) OTDIOB63 IL21R_HUMAN Decreases Expression [39]
UPF0606 protein KIAA1549 (KIAA1549) OTA5B18F K1549_HUMAN Increases Expression [39]
CD209 antigen (CD209) OTCAX8NI CD209_HUMAN Decreases Expression [39]
3',5'-cyclic-AMP phosphodiesterase 7B (PDE7B) OTK3SHT2 PDE7B_HUMAN Increases Expression [39]
Potassium channel subfamily K member 9 (KCNK9) OT8P734M KCNK9_HUMAN Decreases Expression [39]
Frizzled-3 (FZD3) OTIWDN78 FZD3_HUMAN Increases Expression [39]
Odorant-binding protein 2b (OBP2B) OTVKMIM4 OBP2B_HUMAN Increases Expression [39]
Proline-rich nuclear receptor coactivator 2 (PNRC2) OTE7W7Y5 PNRC2_HUMAN Increases Expression [39]
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 (B3GAT2) OTNSM9XP B3GA2_HUMAN Decreases Expression [39]
Anoctamin-2 (ANO2) OT650E98 ANO2_HUMAN Decreases Expression [39]
Mitochondrial dynamics protein MIEF1 (MIEF1) OTFSP3FS MID51_HUMAN Decreases Expression [39]
Scavenger receptor cysteine-rich type 1 protein M160 (CD163L1) OTZHN1XQ C163B_HUMAN Decreases Expression [39]
Matrix metalloproteinase-26 (MMP26) OT9O89KU MMP26_HUMAN Decreases Expression [39]
Teashirt homolog 2 (TSHZ2) OTZWBXXY TSH2_HUMAN Increases Expression [39]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) OTWHOVZS BAZ1A_HUMAN Decreases Expression [39]
CDC42 small effector protein 1 (CDC42SE1) OTV3MRFE C42S1_HUMAN Decreases Expression [39]
Cysteinyl leukotriene receptor 2 (CYSLTR2) OTRNEOZ0 CLTR2_HUMAN Decreases Expression [39]
LanC-like protein 2 (LANCL2) OT7KWGMR LANC2_HUMAN Decreases Expression [39]
Cytokine-inducible SH2-containing protein (CISH) OT8T5NYL CISH_HUMAN Decreases Expression [39]
GPI mannosyltransferase 2 (PIGV) OTI6LT46 PIGV_HUMAN Increases Expression [39]
Probable ATP-dependent RNA helicase DDX28 (DDX28) OTIIHNYN DDX28_HUMAN Decreases Expression [39]
SPATS2-like protein (SPATS2L) OTFO07H8 SPS2L_HUMAN Increases Expression [39]
DNA-directed RNA polymerase III subunit RPC5 (POLR3E) OT69PWBM RPC5_HUMAN Decreases Expression [39]
Arginine and glutamate-rich protein 1 (ARGLU1) OTRVRZ4Z ARGL1_HUMAN Increases Expression [39]
Protein FAM118A (FAM118A) OT6EM97E F118A_HUMAN Decreases Expression [39]
Ankyrin repeat and SOCS box protein 6 (ASB6) OTFAJPSF ASB6_HUMAN Decreases Expression [39]
Ras-related protein Rab-20 (RAB20) OTP9OOVS RAB20_HUMAN Decreases Expression [39]
Pre-mRNA-splicing factor CWC25 homolog (CWC25) OT96LFJH CWC25_HUMAN Decreases Expression [39]
Stabilin-1 (STAB1) OTW2HMCE STAB1_HUMAN Decreases Expression [39]
Gamma-2-syntrophin (SNTG2) OTD8HJCD SNTG2_HUMAN Decreases Expression [39]
Cyclin-dependent kinase 12 (CDK12) OTZUDGNU CDK12_HUMAN Decreases Expression [39]
Placenta-specific gene 8 protein (PLAC8) OT3SYRUJ PLAC8_HUMAN Decreases Expression [39]
Opioid growth factor receptor (OGFR) OTROS6RJ OGFR_HUMAN Decreases Expression [39]
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22) OT452ZDC ADA22_HUMAN Increases Expression [39]
SLAIN motif-containing protein 2 (SLAIN2) OTSM5QIO SLAI2_HUMAN Increases Expression [39]
RNA-binding protein 27 (RBM27) OTBVP6VJ RBM27_HUMAN Increases Expression [39]
Arginine-glutamic acid dipeptide repeats protein (RERE) OT3G4GBZ RERE_HUMAN Increases Expression [39]
Cardiotrophin-like cytokine factor 1 (CLCF1) OTHQUDDI CLCF1_HUMAN Decreases Expression [39]
Cornulin (CRNN) OTAORBR4 CRNN_HUMAN Increases Expression [39]
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) OTP9COQT PISD_HUMAN Decreases Expression [39]
ATP-binding cassette sub-family F member 2 (ABCF2) OTXIBZ3N ABCF2_HUMAN Decreases Expression [39]
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2) OTHTAM54 AAKG2_HUMAN Decreases Expression [39]
Poly polymerase 2 (PARP2) OTYL81ZI PARP2_HUMAN Increases Expression [39]
LIM domain-containing protein 1 (LIMD1) OTN1CG6R LIMD1_HUMAN Decreases Expression [39]
Armadillo repeat-containing X-linked protein 3 (ARMCX3) OTMG7RWW ARMX3_HUMAN Increases Expression [39]
Max-like protein X (MLX) OTZ74KFI MLX_HUMAN Decreases Expression [39]
NPC1-like intracellular cholesterol transporter 1 (NPC1L1) OT6GWW1P NPCL1_HUMAN Increases Expression [39]
Adhesion G protein-coupled receptor E2 (ADGRE2) OTUYJVYG AGRE2_HUMAN Decreases Expression [39]
Dimethylglycine dehydrogenase, mitochondrial (DMGDH) OTPJEWQ8 M2GD_HUMAN Increases Expression [39]
Importin-11 (IPO11) OTG19WN0 IPO11_HUMAN Decreases Expression [39]
Methyl-CpG-binding domain protein 1 (MBD1) OTD19VO6 MBD1_HUMAN Increases Expression [39]
Adherens junction-associated protein 1 (AJAP1) OTAAW121 AJAP1_HUMAN Decreases Expression [39]
Zinc finger protein Helios (IKZF2) OTZIMARJ IKZF2_HUMAN Increases Expression [39]
Nuclear pore complex protein Nup50 (NUP50) OTOZ98K3 NUP50_HUMAN Decreases Expression [39]
Transcription factor-like 5 protein (TCFL5) OTJL4348 TCFL5_HUMAN Decreases Expression [39]
Malignant T-cell-amplified sequence 1 (MCTS1) OT7SAOJP MCTS1_HUMAN Increases Expression [39]
Signal-transducing adaptor protein 1 (STAP1) OTUTZH0W STAP1_HUMAN Increases Expression [39]
Hippocalcin-like protein 4 (HPCAL4) OT793RNP HPCL4_HUMAN Decreases Expression [39]
Ornithine decarboxylase antizyme 3 (OAZ3) OT8Q5PVB OAZ3_HUMAN Increases Expression [39]
Protocadherin gamma-C3 (PCDHGC3) OTDXTUMI PCDGK_HUMAN Increases Expression [39]
Rab effector Noc2 (RPH3AL) OT9VFJEL RPH3L_HUMAN Increases Expression [39]
Trinucleotide repeat-containing gene 6B protein (TNRC6B) OTGVT0SH TNR6B_HUMAN Increases Expression [39]
Protein Smaug homolog 1 (SAMD4A) OT4MKCC8 SMAG1_HUMAN Increases Expression [39]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) OTEU05TX PPR3C_HUMAN Increases Expression [39]
Solute carrier family 22 member 13 (SLC22A13) OTM96T5U S22AD_HUMAN Increases Expression [39]
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) OTUN9GUS NOD1_HUMAN Decreases Expression [39]
Inversin (INVS) OT8KPESR INVS_HUMAN Increases Expression [39]
F-box/WD repeat-containing protein 1A (BTRC) OT2EZDGR FBW1A_HUMAN Increases Expression [39]
Sodium/hydrogen exchanger 8 (SLC9A8) OTR56QTT SL9A8_HUMAN Decreases Expression [39]
Protein strawberry notch homolog 2 (SBNO2) OT1C6J3K SBNO2_HUMAN Decreases Expression [39]
Serine/threonine-protein kinase SIK3 (SIK3) OTH0V1L5 SIK3_HUMAN Decreases Expression [39]
Hypoxia-inducible factor 3-alpha (HIF3A) OTPWAAMC HIF3A_HUMAN Decreases Expression [39]
Long-chain fatty acid transport protein 6 (SLC27A6) OT2AJU6L S27A6_HUMAN Increases Expression [39]
G-protein coupled receptor 55 (GPR55) OTUSATXO GPR55_HUMAN Decreases Expression [39]
RNA-binding motif protein, X-linked 2 (RBMX2) OTGGU7N1 RBMX2_HUMAN Decreases Expression [39]
Nucleolar complex protein 2 homolog (NOC2L) OTNT7R33 NOC2L_HUMAN Decreases Expression [39]
DDB1- and CUL4-associated factor 1 (DCAF1) OT3ZDVOE DCAF1_HUMAN Decreases Expression [39]
Meiosis regulator and mRNA stability factor 1 (MARF1) OTYRJ4V2 MARF1_HUMAN Increases Expression [39]
Lysyl oxidase homolog 2 (LOXL2) OTRT46B5 LOXL2_HUMAN Increases Expression [39]
Cyanocobalamin reductase / alkylcobalamin dealkylase (MMACHC) OTX0TT3W MMAC_HUMAN Increases Expression [39]
Protocadherin gamma-A9 (PCDHGA9) OTKJE2H2 PCDG9_HUMAN Increases Expression [39]
Protocadherin gamma-A3 (PCDHGA3) OTTOGYJA PCDG3_HUMAN Decreases Expression [39]
Doublesex- and mab-3-related transcription factor 1 (DMRT1) OT5PU9U1 DMRT1_HUMAN Decreases Expression [39]
RNA-binding protein 8A (RBM8A) OT5SR6G0 RBM8A_HUMAN Decreases Expression [39]
Solute carrier family 12 member 7 (SLC12A7) OT29GM25 S12A7_HUMAN Decreases Expression [39]
Gap junction alpha-3 protein (GJA3) OTXV6ETF CXA3_HUMAN Increases Expression [39]
Peroxisomal membrane protein 4 (PXMP4) OTNDYSHU PXMP4_HUMAN Increases Expression [39]
Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1) OTSPVITK STYL1_HUMAN Decreases Expression [39]
DNA (DNMT3A) OTEJP0GH DNM3A_HUMAN Increases Expression [39]
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) OT4ZSEEE IF2B2_HUMAN Increases Expression [39]
Transcription factor E2F8 (E2F8) OTQKZGFP E2F8_HUMAN Decreases Expression [40]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Increases Expression [40]
Citron Rho-interacting kinase (CIT) OTOZDKPG CTRO_HUMAN Decreases Expression [40]
Kinetochore protein NDC80 homolog (NDC80) OTS7D306 NDC80_HUMAN Decreases Expression [40]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Decreases Expression [40]
Protein Mis18-beta (OIP5) OTI5C2DE MS18B_HUMAN Decreases Expression [40]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) OT80DZMT BUB1_HUMAN Decreases Expression [40]
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3) OTX1C2GS DYRK3_HUMAN Increases Expression [40]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Decreases Expression [40]
Hyaluronan mediated motility receptor (HMMR) OT4M0JTZ HMMR_HUMAN Decreases Expression [40]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Increases Expression [40]
G2/mitotic-specific cyclin-B2 (CCNB2) OTIEXTDK CCNB2_HUMAN Decreases Expression [40]
Kinesin-like protein KIF20A (KIF20A) OTXOQHE0 KI20A_HUMAN Decreases Expression [40]
Chromosome-associated kinesin KIF4A (KIF4A) OT3UWL7D KIF4A_HUMAN Decreases Expression [40]
Integrin beta-like protein 1 (ITGBL1) OTJDHE17 ITGBL_HUMAN Decreases Expression [40]
Aldehyde dehydrogenase 1A1 (ALDH1A1) OTCUWZKB AL1A1_HUMAN Decreases Expression [40]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Decreases Expression [40]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Decreases Expression [40]
Histone H1.5 (H1-5) OTAN7RD9 H15_HUMAN Decreases Expression [40]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [40]
Lamin-B1 (LMNB1) OT100T3P LMNB1_HUMAN Decreases Expression [40]
Interleukin-11 (IL11) OTXHN86R IL11_HUMAN Increases Expression [40]
Diamine acetyltransferase 1 (SAT1) OT52AU22 SAT1_HUMAN Increases Expression [40]
Arylacetamide deacetylase (AADAC) OT8VACT2 AAAD_HUMAN Increases Expression [40]
GTP cyclohydrolase 1 (GCH1) OTOZ6NSL GCH1_HUMAN Increases Expression [40]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) OTOB6J6R RIR2_HUMAN Decreases Expression [40]
Histone H2B type 1-B (H2BC3) OT1BLFJO H2B1B_HUMAN Decreases Expression [40]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [40]
Proliferation marker protein Ki-67 (MKI67) OTA8N1QI KI67_HUMAN Decreases Expression [40]
Centromere protein F (CENPF) OT7AG0SW CENPF_HUMAN Decreases Expression [40]
DNA primase small subunit (PRIM1) OTWWP8Y6 PRI1_HUMAN Decreases Expression [40]
Kinesin-like protein KIF11 (KIF11) OTHRGLCQ KIF11_HUMAN Decreases Expression [40]
Serine/threonine-protein kinase PLK1 (PLK1) OTRZX45T PLK1_HUMAN Decreases Expression [40]
DNA polymerase epsilon subunit 2 (POLE2) OTAC9V6L DPOE2_HUMAN Decreases Expression [40]
Sestrin-2 (SESN2) OT889IXY SESN2_HUMAN Increases Expression [40]
Rho-related GTP-binding protein RhoE (RND3) OTXMXPIH RND3_HUMAN Increases Expression [40]
Histone H3.1 (H3C1) OTGBGOZW H31_HUMAN Decreases Expression [40]
Arginase-2, mitochondrial (ARG2) OTCPI0E8 ARGI2_HUMAN Increases Expression [40]
G-protein-signaling modulator 2 (GPSM2) OT6RPMRM GPSM2_HUMAN Decreases Expression [40]
55 kDa erythrocyte membrane protein (MPP1) OTA2ENZQ EM55_HUMAN Decreases Expression [40]
Kinesin-like protein KIF23 (KIF23) OTY850JC KIF23_HUMAN Decreases Expression [40]
Forkhead box protein M1 (FOXM1) OT5887KR FOXM1_HUMAN Decreases Expression [40]
Magnesium transporter NIPA4 (NIPAL4) OT43JC9A NIPA4_HUMAN Increases Expression [40]
Cell division cycle protein 20 homolog (CDC20) OTCOEZRV CDC20_HUMAN Decreases Expression [40]
TNF receptor-associated factor 1 (TRAF1) OTTLM5RU TRAF1_HUMAN Increases Expression [40]
S-phase kinase-associated protein 2 (SKP2) OTD5B41X SKP2_HUMAN Decreases Expression [40]
DNA replication licensing factor MCM6 (MCM6) OTKLIAWT MCM6_HUMAN Decreases Expression [40]
Maternal embryonic leucine zipper kinase (MELK) OTEY2UQA MELK_HUMAN Decreases Expression [40]
Condensin complex subunit 2 (NCAPH) OTXOS97C CND2_HUMAN Decreases Expression [40]
PCNA-associated factor (PCLAF) OTMVIOUU PAF15_HUMAN Decreases Expression [40]
Disks large-associated protein 5 (DLGAP5) OTWCN39U DLGP5_HUMAN Decreases Expression [40]
Nuclear factor interleukin-3-regulated protein (NFIL3) OTQH9HM3 NFIL3_HUMAN Increases Expression [40]
Cyclin-dependent kinase inhibitor 3 (CDKN3) OTBE3H07 CDKN3_HUMAN Decreases Expression [40]
DNA excision repair protein ERCC-6-like (ERCC6L) OTE9V7D9 ERC6L_HUMAN Decreases Expression [40]
Borealin (CDCA8) OT17D55D BOREA_HUMAN Decreases Expression [40]
Shugoshin 2 (SGO2) OTNGJDS8 SGO2_HUMAN Decreases Expression [40]
Fidgetin (FIGN) OTJF6EZR FIGN_HUMAN Decreases Expression [40]
RRP12-like protein (RRP12) OTQQAEH4 RRP12_HUMAN Increases Expression [40]
Alkaline ceramidase 2 (ACER2) OTS3DDE5 ACER2_HUMAN Increases Expression [40]
DEP domain-containing protein 1A (DEPDC1) OT0JWE1B DEP1A_HUMAN Decreases Expression [40]
Rho GTPase-activating protein 11A (ARHGAP11A) OTVQCFVP RHGBA_HUMAN Decreases Expression [40]
Transmembrane protein 71 (TMEM71) OTA7W26O TMM71_HUMAN Decreases Expression [40]
Serine protease FAM111B (FAM111B) OT9IQ9NV F111B_HUMAN Decreases Expression [40]
Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) OTO4UIDB CCBE1_HUMAN Decreases Expression [40]
Lysine-specific demethylase 7A (KDM7A) OT1VGYCX KDM7A_HUMAN Increases Expression [40]
Alkylglycerol monooxygenase (AGMO) OTGMAHAT ALKMO_HUMAN Decreases Expression [40]
Condensin-2 complex subunit G2 (NCAPG2) OTZYENKO CNDG2_HUMAN Decreases Expression [40]
Kinesin-like protein KIF18B (KIF18B) OTOBUDOE KI18B_HUMAN Decreases Expression [40]
Abnormal spindle-like microcephaly-associated protein (ASPM) OTKXQMNA ASPM_HUMAN Decreases Expression [40]
Kinetochore protein Spc24 (SPC24) OT1HVYV4 SPC24_HUMAN Decreases Expression [40]
Meiosis-specific nuclear structural protein 1 (MNS1) OT67F3JQ MNS1_HUMAN Decreases Expression [40]
SHC SH2 domain-binding protein 1 (SHCBP1) OT3A21CM SHCBP_HUMAN Decreases Expression [40]
Kelch repeat and BTB domain-containing protein 8 (KBTBD8) OTO8X1UF KBTB8_HUMAN Increases Expression [40]
Kinetochore scaffold 1 (KNL1) OT4Q3LHV KNL1_HUMAN Decreases Expression [40]
Endonuclease 8-like 3 (NEIL3) OTBCI2NS NEIL3_HUMAN Decreases Expression [40]
Enkurin (ENKUR) OTXXBBQT ENKUR_HUMAN Increases Expression [40]
Transcription initiation factor TFIID subunit 4B (TAF4B) OTCICY31 TAF4B_HUMAN Increases Expression [40]
Histone H2B type 1-H (H2BC9) OTQ9XX72 H2B1H_HUMAN Decreases Expression [40]
Proline-rich protein 11 (PRR11) OT2JJ08Z PRR11_HUMAN Decreases Expression [40]
Lymphokine-activated killer T-cell-originated protein kinase (PBK) OT5Z27TW TOPK_HUMAN Decreases Expression [40]
Guanine nucleotide exchange factor C9orf72 (C9ORF72) OT0WH38E CI072_HUMAN Increases Expression [40]
Sperm-associated antigen 5 (SPAG5) OTCLJ56M SPAG5_HUMAN Decreases Expression [40]
Centromere protein K (CENPK) OTKPUF8K CENPK_HUMAN Decreases Expression [40]
Transmembrane protein 106C (TMEM106C) OTDOD9OQ T106C_HUMAN Decreases Expression [40]
Kinesin-like protein KIFC1 (KIFC1) OTNQDS00 KIFC1_HUMAN Decreases Expression [40]
Fanconi anemia group J protein (BRIP1) OT38QBD4 FANCJ_HUMAN Decreases Expression [40]
Nucleolar and spindle-associated protein 1 (NUSAP1) OT85HIJ5 NUSAP_HUMAN Decreases Expression [40]
Fanconi anemia group D2 protein (FANCD2) OTVEB5LF FACD2_HUMAN Decreases Expression [40]
Kinetochore protein Nuf2 (NUF2) OTOOQL35 NUF2_HUMAN Decreases Expression [40]
Ankyrin repeat family A protein 2 (ANKRA2) OTLSLV5A ANRA2_HUMAN Increases Expression [40]
Kinetochore protein Spc25 (SPC25) OTCAS0OH SPC25_HUMAN Decreases Expression [40]
Anillin (ANLN) OTXJY54C ANLN_HUMAN Decreases Expression [40]
Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7) OT3QER33 ENTP7_HUMAN Increases Expression [40]
Phospholipid scramblase 4 (PLSCR4) OT2AMYLY PLS4_HUMAN Decreases Expression [40]
Kinesin-like protein KIF15 (KIF15) OTJRJEXL KIF15_HUMAN Decreases Expression [40]
Histone chaperone ASF1B (ASF1B) OTKXX12I ASF1B_HUMAN Decreases Expression [40]
GTPase IMAP family member 2 (GIMAP2) OTHH2EFT GIMA2_HUMAN Decreases Expression [40]
Kelch-like protein 21 (KLHL21) OT28Y2LQ KLH21_HUMAN Increases Expression [40]
DNA replication complex GINS protein PSF2 (GINS2) OT974IYI PSF2_HUMAN Decreases Expression [40]
E3 ubiquitin-protein ligase RNF114 (RNF114) OTF06FRP RN114_HUMAN Increases Expression [40]
POTE ankyrin domain family member F (POTEF) OTV3WXYE POTEF_HUMAN Decreases Expression [41]
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10) OTBURQ3A NDUAA_HUMAN Increases Expression [41]
Fructose-bisphosphate aldolase A (ALDOA) OTWRFTIB ALDOA_HUMAN Decreases Expression [41]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Increases Expression [41]
Keratin, type II cytoskeletal 8 (KRT8) OTTM4X11 K2C8_HUMAN Decreases Expression [41]
Alpha-enolase (ENO1) OTB1KWJS ENOA_HUMAN Increases Expression [41]
Nucleophosmin (NPM1) OTTBYYT0 NPM_HUMAN Increases Expression [41]
Phosphoglycerate mutase 1 (PGAM1) OTZ5DB06 PGAM1_HUMAN Decreases Expression [41]
Proteasome subunit alpha type-2 (PSMA2) OTJRT2ZL PSA2_HUMAN Decreases Expression [41]
Endoplasmic reticulum resident protein 29 (ERP29) OTNKANMH ERP29_HUMAN Decreases Expression [41]
Triosephosphate isomerase (TPI1) OT14KP4B TPIS_HUMAN Decreases Expression [41]
Poly(rC)-binding protein 1 (PCBP1) OTHN0TD7 PCBP1_HUMAN Decreases Expression [41]
Fascin (FSCN1) OTTGIHTM FSCN1_HUMAN Decreases Expression [41]
Lambda-crystallin homolog (CRYL1) OT0SJSJM CRYL1_HUMAN Increases Expression [41]
NF-kappa-B inhibitor epsilon (NFKBIE) OTLAYEL9 IKBE_HUMAN Decreases Expression [87]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Increases Secretion [88]
Importin subunit alpha-4 (KPNA3) OTLI3TM2 IMA4_HUMAN Decreases Expression [89]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11) OTJEPKEQ TNF11_HUMAN Decreases Expression [88]
Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) OTVHOL9B TR10C_HUMAN Increases Expression [87]
Angiopoietin-2 (ANGPT2) OTEQK65P ANGP2_HUMAN Increases Expression [43]
Protein SLC31A2 (SLC31A2) OTQC136Q COPT2_HUMAN Increases Expression [90]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Increases Expression [87]
Mitogen-activated protein kinase kinase kinase 7 (MAP3K7) OTUXEASC M3K7_HUMAN Decreases Expression [89]
Tumor necrosis factor ligand superfamily member 14 (TNFSF14) OT5QRF09 TNF14_HUMAN Increases Expression [91]
Protein regulator of cytokinesis 1 (PRC1) OTHD0XS0 PRC1_HUMAN Decreases Expression [42]
Integral membrane protein 2A (ITM2A) OT590V63 ITM2A_HUMAN Increases Expression [46]
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) OTUG02U7 KHDR3_HUMAN Increases Expression [46]
Dual specificity protein phosphatase 14 (DUSP14) OTGODFCR DUS14_HUMAN Increases Expression [90]
CCN family member 4 (CCN4) OT69BER9 CCN4_HUMAN Decreases Expression [44]
Superoxide dismutase (SOD1) OT39TA1L SODC_HUMAN Increases Expression [92]
Cystatin-A (CSTA) OT1K68KE CYTA_HUMAN Increases Expression [46]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Increases Expression [93]
Vasopressin-neurophysin 2-copeptin (AVP) OTAVZ76K NEU2_HUMAN Increases Secretion [94]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Increases Expression [92]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Increases Expression [46]
T-cell surface glycoprotein CD4 (CD4) OT7Z5LNF CD4_HUMAN Decreases Expression [95]
T-cell surface glycoprotein CD8 alpha chain (CD8A) OTDWQJXK CD8A_HUMAN Decreases Expression [95]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Decreases Expression [46]
Albumin (ALB) OTVMM513 ALBU_HUMAN Decreases Secretion [96]
Heat shock protein beta-1 (HSPB1) OTHFZ8ED HSPB1_HUMAN Increases Expression [90]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Increases Expression [97]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Phosphorylation [98]
Integrin beta-1 (ITGB1) OT6G1IAR ITB1_HUMAN Decreases Expression [89]
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Increases Expression [99]
Complement decay-accelerating factor (CD55) OTZ3HWTO DAF_HUMAN Increases Expression [45]
Stromelysin-1 (MMP3) OTGBI74Z MMP3_HUMAN Decreases Expression [95]
Dihydropteridine reductase (QDPR) OTSKOIUX DHPR_HUMAN Decreases Activity [100]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [101]
Intestinal-type alkaline phosphatase (ALPI) OTTQ468O PPBI_HUMAN Increases Activity [102]
Adenosine receptor A3 (ADORA3) OTHO1BLK AA3R_HUMAN Increases Expression [103]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Decreases Expression [95]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [104]
Ornithine decarboxylase (ODC1) OTNDAGRR DCOR_HUMAN Increases Expression [102]
Bone morphogenetic protein 2 (BMP2) OT23T37S BMP2_HUMAN Increases Expression [91]
Tissue factor (F3) OT3MSU3B TF_HUMAN Increases Expression [105]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Increases Expression [87]
Aminopeptidase N (ANPEP) OTP3WYFD AMPN_HUMAN Increases Expression [106]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Phosphorylation [107]
Cyclic AMP-responsive element-binding protein 1 (CREB1) OT1MDLA1 CREB1_HUMAN Decreases Expression [89]
E-selectin (SELE) OT33RZWY LYAM2_HUMAN Decreases Expression [95]
Platelet glycoprotein 4 (CD36) OT5CZWKY CD36_HUMAN Increases Expression [108]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Decreases Expression [89]
Desmin (DES) OTI09KBW DESM_HUMAN Increases Expression [109]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Increases Expression [46]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [48]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Decreases Expression [92]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) OTVLI4DD TNAP3_HUMAN Decreases Expression [87]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Increases Expression [90]
Integrin alpha-6 (ITGA6) OT3FA39C ITA6_HUMAN Increases Expression [46]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [110]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Increases Expression [87]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Decreases Expression [104]
Dual specificity protein phosphatase 1 (DUSP1) OTN6BR75 DUS1_HUMAN Increases Expression [90]
Adenosine receptor A2a (ADORA2A) OTVRBZ0I AA2AR_HUMAN Increases Expression [111]
Adenosine receptor A2b (ADORA2B) OTCDYBBP AA2BR_HUMAN Increases Expression [111]
Interleukin-12 subunit alpha (IL12A) OTDQT8GI IL12A_HUMAN Decreases Expression [112]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Increases Expression [46]
Macrosialin (CD68) OTOYEY3J CD68_HUMAN Decreases Expression [113]
Interleukin-13 (IL13) OTI4YS3Y IL13_HUMAN Decreases Secretion [96]
Basigin (BSG) OTD0CVEC BASI_HUMAN Decreases Expression [89]
TGF-beta receptor type-2 (TGFBR2) OT3P7GZP TGFR2_HUMAN Decreases Expression [89]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [107]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Expression [114]
Nuclear receptor subfamily 4 group A member 2 (NR4A2) OT3F9IR2 NR4A2_HUMAN Decreases Expression [113]
Mitogen-activated protein kinase 9 (MAPK9) OTCEVJ9E MK09_HUMAN Increases Expression [115]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [115]
MAP kinase-activated protein kinase 2 (MAPKAPK2) OT460SBO MAPK2_HUMAN Increases Expression [90]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Expression [87]
Caveolin-2 (CAV2) OT1FGRQX CAV2_HUMAN Increases Expression [46]
Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6) OTK13JKC MP2K6_HUMAN Decreases Expression [90]
Collagen alpha-4(IV) chain (COL4A4) OT9G0MCT CO4A4_HUMAN Increases Expression [109]
Phospholipid transfer protein (PLTP) OTVJJO5Z PLTP_HUMAN Increases Expression [46]
Caspase-6 (CASP6) OTXLD3EC CASP6_HUMAN Decreases Expression [110]
Cadherin-4 (CDH4) OT8LH3HN CADH4_HUMAN Decreases Expression [46]
Interleukin-2 (IL2) OTGI4NSA IL2_HUMAN Decreases Secretion [116]
Actin-related protein 2 (ACTR2) OT3C8U5T ARP2_HUMAN Decreases Expression [89]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Increases Expression [96]
Ras-related C3 botulinum toxin substrate 1 (RAC1) OTKRO61U RAC1_HUMAN Increases Expression [90]
Protein jagged-1 (JAG1) OT3LGT6K JAG1_HUMAN Increases Expression [46]
Protein S100-A12 (S100A12) OTF9IIXW S10AC_HUMAN Increases Expression [87]
CD83 antigen (CD83) OT1V4WQF CD83_HUMAN Decreases Expression [87]
Transgelin (TAGLN) OTAEZ0KP TAGL_HUMAN Decreases Expression [44]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Increases Expression [87]
Bcl-2-interacting killer (BIK) OTTH1T3D BIK_HUMAN Increases Expression [110]
RING-type E3 ubiquitin-protein ligase PPIL2 (PPIL2) OTL9Y4IO PPIL2_HUMAN Decreases Expression [89]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Increases Expression [107]
Frizzled-2 (FZD2) OT952ML1 FZD2_HUMAN Decreases Expression [46]
Structural maintenance of chromosomes protein 1A (SMC1A) OT9ZMRK9 SMC1A_HUMAN Decreases Expression [89]
Angiopoietin-1 (ANGPT1) OTVZ1NG3 ANGP1_HUMAN Decreases Expression [43]
Histone-lysine N-methyltransferase EZH2 (EZH2) OTIEHTKW EZH2_HUMAN Decreases Expression [107]
Mitogen-activated protein kinase 14 (MAPK14) OT5TCO3O MK14_HUMAN Decreases Expression [90]
Occludin (OCLN) OTSUTVWL OCLN_HUMAN Decreases Expression [92]
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 (B3GNT9) OTO385AU B3GN9_HUMAN Increases Expression [46]
Jouberin (AHI1) OT8K2YWY AHI1_HUMAN Increases Expression [117]
Retinoic acid-induced protein 3 (GPRC5A) OTPOCWR7 RAI3_HUMAN Increases Expression [46]
Aquaporin-3 (AQP3) OT2J7JPD AQP3_HUMAN Decreases Expression [87]
Protein Jumonji (JARID2) OT14UM8H JARD2_HUMAN Decreases Expression [48]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [107]
Perilipin-2 (PLIN2) OTRXJ9UN PLIN2_HUMAN Increases Expression [46]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5) OTH91ETM SIA7E_HUMAN Decreases Expression [46]
Protein FAM117A (FAM117A) OT2FBGGV F117A_HUMAN Decreases Expression [48]
Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2) OTG6F93V PPIP2_HUMAN Increases Expression [46]
Bcl-2-like protein 12 (BCL2L12) OTS6IFZY B2L12_HUMAN Decreases Expression [118]
Mid1-interacting protein 1 (MID1IP1) OTFCORJM M1IP1_HUMAN Increases Expression [46]
AP-5 complex subunit sigma-1 (AP5S1) OTGS53SC AP5S1_HUMAN Increases Expression [48]
DNA damage-inducible transcript 4 protein (DDIT4) OTHY8SY4 DDIT4_HUMAN Increases Expression [46]
Heat shock protein beta-8 (HSPB8) OT0I83YS HSPB8_HUMAN Increases Expression [46]
Endothelial protein C receptor (PROCR) OTRHED17 EPCR_HUMAN Increases Expression [46]
Forkhead box protein J3 (FOXJ3) OTXAUJ47 FOXJ3_HUMAN Decreases Expression [89]
RWD domain-containing protein 3 (RWDD3) OTE76DY5 RWDD3_HUMAN Increases Expression [48]
Dual specificity protein phosphatase 10 (DUSP10) OTNG467B DUS10_HUMAN Increases Expression [90]
Elongation factor 1-alpha 1 (EEF1A1) OT00THXS EF1A1_HUMAN Decreases Response To Substance [119]
Glycoprotein hormones alpha chain (CGA) OT00U3Y3 GLHA_HUMAN Affects Response To Substance [49]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Affects Response To Substance [49]
Mediator of RNA polymerase II transcription subunit 15 (MED15) OT0D0JVD MED15_HUMAN Affects Response To Substance [49]
Phospholipid phosphatase 1 (PLPP1) OT0IIMI5 PLPP1_HUMAN Affects Response To Substance [49]
Guanine nucleotide-binding protein subunit alpha-11 (GNA11) OT0K99TO GNA11_HUMAN Affects Response To Substance [49]
Succinate--CoA ligase subunit beta, mitochondrial (SUCLG2) OT0KHLY2 SUCB2_HUMAN Affects Response To Substance [49]
Insulin-like growth factor-binding protein 7 (IGFBP7) OT1D416P IBP7_HUMAN Affects Response To Substance [49]
Alpha-centractin (ACTR1A) OT1QAU16 ACTZ_HUMAN Affects Response To Substance [49]
Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1) OT1QHOS2 NF2L1_HUMAN Affects Response To Substance [49]
DNA-directed RNA polymerase I subunit RPA12 (POLR1H) OT30S3SB RPA12_HUMAN Decreases Response To Substance [120]
Epidermal growth factor-like protein 6 (EGFL6) OT331X59 EGFL6_HUMAN Decreases Response To Substance [50]
Protein FAM171A1 (FAM171A1) OT33BHEP F1711_HUMAN Affects Response To Substance [49]
Cip1-interacting zinc finger protein (CIZ1) OT3UKHPI CIZ1_HUMAN Affects Response To Substance [49]
Transcobalamin-2 (TCN2) OT41D0L3 TCO2_HUMAN Affects Metabolism [121]
Elafin (PI3) OT47MTC3 ELAF_HUMAN Affects Response To Substance [49]
CCR4-NOT transcription complex subunit 3 (CNOT3) OT4D5Z9L CNOT3_HUMAN Affects Response To Substance [49]
ATP-dependent RNA helicase DHX15 (DHX15) OT4F98TK DHX15_HUMAN Affects Response To Substance [49]
Fibroblast growth factor receptor 1 (FGFR1) OT4GLCXW FGFR1_HUMAN Affects Response To Substance [49]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Affects Response To Substance [49]
PRELI domain containing protein 3B (PRELID3B) OT4TRT4K PLD3B_HUMAN Affects Response To Substance [49]
Exocyst complex component 7 (EXOC7) OT4YA137 EXOC7_HUMAN Affects Response To Substance [49]
Large proline-rich protein BAG6 (BAG6) OT4Z0S2U BAG6_HUMAN Affects Response To Substance [49]
Transducin-like enhancer protein 1 (TLE1) OT50MRZ1 TLE1_HUMAN Affects Response To Substance [49]
Protein phosphatase 3 catalytic subunit alpha (PPP3CA) OT58PUEN PP2BA_HUMAN Affects Response To Substance [49]
Transcription termination factor 2 (TTF2) OT5LJOWM TTF2_HUMAN Affects Response To Substance [49]
Protein kinase C alpha type (PRKCA) OT5UWNRD KPCA_HUMAN Decreases Response To Substance [75]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Decreases Response To Substance [50]
Nuclear pore complex protein Nup88 (NUP88) OT647WOR NUP88_HUMAN Affects Response To Substance [49]
Mitochondrial enolase superfamily member 1 (ENOSF1) OT65D3ZK ENOF1_HUMAN Affects Response To Substance [49]
C-C motif chemokine 4 (CCL4) OT6B8P25 CCL4_HUMAN Decreases Response To Substance [122]
Melanoma-associated antigen D1 (MAGED1) OT6EOLFC MAGD1_HUMAN Affects Response To Substance [49]
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PPRC1) OT6GB3WR PPRC1_HUMAN Affects Response To Substance [49]
Follistatin-related protein 1 (FSTL1) OT6KEZUD FSTL1_HUMAN Affects Response To Substance [49]
Glutathione peroxidase 3 (GPX3) OT6PK94R GPX3_HUMAN Affects Response To Substance [49]
Dual specificity protein phosphatase 4 (DUSP4) OT6WAO12 DUS4_HUMAN Affects Response To Substance [49]
Semenogelin-1 (SEMG1) OT6Z4BPQ SEMG1_HUMAN Affects Response To Substance [49]
GTPase KRas (KRAS) OT78QCN8 RASK_HUMAN Increases Response To Substance [123]
Polyunsaturated fatty acid 5-lipoxygenase (ALOX5) OT7FOIK2 LOX5_HUMAN Affects Response To Substance [49]
Glutamate receptor ionotropic, NMDA 3B (GRIN3B) OT7T1OJP NMD3B_HUMAN Affects Response To Substance [49]
Interferon-inducible protein AIM2 (AIM2) OT86QUI8 AIM2_HUMAN Affects Response To Substance [49]
Tyrosine-protein kinase Lck (LCK) OT883FG9 LCK_HUMAN Affects Response To Substance [49]
Peroxisomal membrane protein 11A (PEX11A) OT8MJ9CJ PX11A_HUMAN Affects Response To Substance [49]
Mediator of RNA polymerase II transcription subunit 16 (MED16) OT8SCI48 MED16_HUMAN Affects Response To Substance [49]
Annexin A11 (ANXA11) OT8SRY1C ANX11_HUMAN Affects Response To Substance [49]
ER lumen protein-retaining receptor 1 (KDELR1) OT8YBS5G ERD21_HUMAN Affects Response To Substance [49]
Prostate tumor-overexpressed gene 1 protein (PTOV1) OT94WT5X PTOV1_HUMAN Affects Response To Substance [49]
Cyclic AMP-responsive element-binding protein 3 (CREB3) OT9617UO CREB3_HUMAN Affects Response To Substance [49]
Runt-related transcription factor 2 (RUNX2) OT97RQQM RUNX2_HUMAN Decreases Response To Substance [91]
Fibromodulin (FMOD) OT9EJ5H8 FMOD_HUMAN Affects Response To Substance [49]
Epsilon-sarcoglycan (SGCE) OT9F17JB SGCE_HUMAN Affects Response To Substance [49]
Tyrosine-protein kinase Fer (FER) OT9JR7AE FER_HUMAN Affects Response To Substance [49]
Receptor-type tyrosine-protein phosphatase gamma (PTPRG) OT9N2WOF PTPRG_HUMAN Affects Response To Substance [49]
Extended synaptotagmin-1 (ESYT1) OTA8NSJF ESYT1_HUMAN Affects Response To Substance [49]
HLA class I histocompatibility antigen, A alpha chain (HLA-A) OTAH14LU HLAA_HUMAN Affects Response To Substance [49]
Cleavage and polyadenylation specificity factor subunit 1 (CPSF1) OTAU1KOM CPSF1_HUMAN Affects Response To Substance [49]
PDZ and LIM domain protein 7 (PDLIM7) OTAZVODU PDLI7_HUMAN Affects Response To Substance [49]
Coagulation factor XII (F12) OTBFD2FU FA12_HUMAN Affects Response To Substance [49]
Protein DGCR6 (DGCR6) OTBOXM33 DGCR6_HUMAN Affects Response To Substance [49]
Histone H1.10 (H1-10) OTBWDA4E H1X_HUMAN Affects Response To Substance [49]
Potassium channel subfamily K member 1 (KCNK1) OTBXPTKX KCNK1_HUMAN Affects Response To Substance [49]
CCN family member 2 (CCN2) OTC39NSU CCN2_HUMAN Decreases Response To Substance [124]
Serine protease HTRA2, mitochondrial (HTRA2) OTC7616F HTRA2_HUMAN Affects Response To Substance [122]
Cystathionine gamma-lyase (CTH) OTC90LA0 CGL_HUMAN Affects Response To Substance [49]
Creatine kinase U-type, mitochondrial (CKMT1A) OTCINHH5 KCRU_HUMAN Affects Response To Substance [49]
KRR1 small subunit processome component homolog (KRR1) OTCMJ3K3 KRR1_HUMAN Affects Response To Substance [49]
Phosphoribosylformylglycinamidine synthase (PFAS) OTCOBYYK PUR4_HUMAN Affects Response To Substance [80]
Adhesion G protein-coupled receptor L2 (ADGRL2) OTCXD2YR AGRL2_HUMAN Affects Response To Substance [49]
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) OTCYYCAC HGS_HUMAN Affects Response To Substance [49]
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1) OTD13PJN RBMS1_HUMAN Affects Response To Substance [49]
Src kinase-associated phosphoprotein 1 (SKAP1) OTD4ZKAL SKAP1_HUMAN Affects Response To Substance [49]
Battenin (CLN3) OTDDKT8R CLN3_HUMAN Affects Response To Substance [49]
Integrin alpha-1 (ITGA1) OTDITIST ITA1_HUMAN Increases Response To Substance [50]
Multiple epidermal growth factor-like domains protein 9 (MEGF9) OTDQWTY4 MEGF9_HUMAN Affects Response To Substance [49]
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) OTDS5WAU PIN1_HUMAN Affects Response To Substance [49]
Cytoskeleton-associated protein 4 (CKAP4) OTDUC9ME CKAP4_HUMAN Affects Response To Substance [49]
Transcription intermediary factor 1-beta (TRIM28) OTE38OBF TIF1B_HUMAN Affects Response To Substance [49]
Cystatin-SN (CST1) OTE4I83Q CYTN_HUMAN Affects Response To Substance [49]
Pseudouridine-5'-phosphatase (PUDP) OTEPEJLX HDHD1_HUMAN Affects Response To Substance [49]
Rho GDP-dissociation inhibitor 1 (ARHGDIA) OTEXWJDO GDIR1_HUMAN Affects Response To Substance [49]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Decreases Response To Substance [75]
Methionine synthase (MTR) OTF2K2TA METH_HUMAN Decreases Response To Substance [80]
CD151 antigen (CD151) OTF3UZS7 CD151_HUMAN Affects Response To Substance [49]
Paraneoplastic antigen Ma2 (PNMA2) OTF5YBQG PNMA2_HUMAN Affects Response To Substance [49]
Endophilin-B2 (SH3GLB2) OTF7BB9S SHLB2_HUMAN Affects Response To Substance [49]
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C) OTF7CGO2 2A5G_HUMAN Affects Response To Substance [49]
Dehydrogenase/reductase SDR family member 2, mitochondrial (DHRS2) OTFHWIY8 DHRS2_HUMAN Affects Response To Substance [49]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Increases Response To Substance [75]
Laminin subunit alpha-2 (LAMA2) OTFROQWE LAMA2_HUMAN Increases Response To Substance [50]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) OTFRWOLM HNRH1_HUMAN Affects Response To Substance [49]
m7GpppN-mRNA hydrolase (DCP2) OTG3VKPS DCP2_HUMAN Affects Response To Substance [49]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2) OTGD8TID FLRT2_HUMAN Affects Response To Substance [49]
Tomoregulin-1 (TMEFF1) OTH6M3CH TEFF1_HUMAN Affects Response To Substance [49]
Phospholipid-transporting ATPase ABCA3 (ABCA3) OTH6MSKQ ABCA3_HUMAN Decreases Response To Substance [125]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (GNG11) OTHIXBGW GBG11_HUMAN Affects Response To Substance [49]
Melanoma-associated antigen 6 (MAGEA6) OTI8S0O2 MAGA6_HUMAN Affects Response To Substance [49]
Nectin-2 (NECTIN2) OTIE0W6O NECT2_HUMAN Affects Response To Substance [49]
Kallikrein-6 (KLK6) OTIEA234 KLK6_HUMAN Affects Response To Substance [49]
Laminin subunit gamma-1 (LAMC1) OTIG527N LAMC1_HUMAN Affects Response To Substance [49]
Serine hydroxymethyltransferase, cytosolic (SHMT1) OTIINA3J GLYC_HUMAN Affects Response To Substance [126]
Spartin (SPART) OTIVOS2I SPART_HUMAN Affects Response To Substance [49]
Protein S100-P (S100P) OTJCXNJG S100P_HUMAN Affects Response To Substance [49]
Polycomb protein EED (EED) OTJFHCDF EED_HUMAN Affects Response To Substance [49]
Sulfate transporter (SLC26A2) OTJNHNTO S26A2_HUMAN Affects Response To Substance [49]
Lysophosphatidic acid receptor 1 (LPAR1) OTJNJQPF LPAR1_HUMAN Affects Response To Substance [49]
Unconventional myosin-VI (MYO6) OTJQYRC7 MYO6_HUMAN Affects Response To Substance [49]
Tetraspanin-4 (TSPAN4) OTKFK57F TSN4_HUMAN Affects Response To Substance [49]
Interferon regulatory factor 6 (IRF6) OTKJ44EV IRF6_HUMAN Affects Response To Substance [49]
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3BGRL3) OTKMW34I SH3L3_HUMAN Affects Response To Substance [49]
Ras-related protein Rab-1A (RAB1A) OTKPHRD0 RAB1A_HUMAN Affects Response To Substance [49]
5'-3' exonuclease PLD3 (PLD3) OTL07SP2 PLD3_HUMAN Affects Response To Substance [49]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Decreases Response To Substance [127]
Death-associated protein kinase 3 (DAPK3) OTLV7EKW DAPK3_HUMAN Affects Response To Substance [49]
Peroxiredoxin-2 (PRDX2) OTLWCY9T PRDX2_HUMAN Decreases Response To Substance [128]
Hemicentin-1 (HMCN1) OTLZAS0P HMCN1_HUMAN Increases Response To Substance [50]
Unconventional myosin-Ie (MYO1E) OTM9YSIZ MYO1E_HUMAN Affects Response To Substance [49]
kinase isozyme 1, mitochondrial (PDK1) OTMABK9Z PDK1_HUMAN Affects Response To Substance [49]
NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8) OTMEAWKO NDUS8_HUMAN Affects Response To Substance [49]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) OTMKHVWC C1TC_HUMAN Affects Response To Substance [129]
Ubiquitin-conjugating enzyme E2 R1 (CDC34) OTNBK390 UB2R1_HUMAN Affects Response To Substance [49]
Glycine cleavage system H protein, mitochondrial (GCSH) OTNC1OKA GCSH_HUMAN Affects Response To Substance [49]
Pulmonary surfactant-associated protein D (SFTPD) OTNKPDJC SFTPD_HUMAN Increases ADR [51]
Hepatoma-derived growth factor-related protein 3 (HDGFL3) OTNN7WYH HDGR3_HUMAN Affects Response To Substance [49]
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) OTNONPMB GLCNE_HUMAN Affects Response To Substance [49]
Splicing factor 3B subunit 1 (SF3B1) OTNTX2DG SF3B1_HUMAN Affects Response To Substance [49]
Protein Tob1 (TOB1) OTNW949D TOB1_HUMAN Affects Response To Substance [49]
ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL6IP4) OTOA8VAL AR6P4_HUMAN Affects Response To Substance [49]
Forkhead box protein N3 (FOXN3) OTOJYJZP FOXN3_HUMAN Affects Response To Substance [49]
Glutathione S-transferase Mu 4 (GSTM4) OTOTF8DU GSTM4_HUMAN Decreases Response To Substance [130]
Solute carrier family 52, riboflavin transporter, member 2 (SLC52A2) OTPC6NXA S52A2_HUMAN Affects Response To Substance [49]
Poly(A) polymerase alpha (PAPOLA) OTPHD65D PAPOA_HUMAN Affects Response To Substance [49]
Centrosomal protein of 57 kDa (CEP57) OTPOHLIX CEP57_HUMAN Affects Response To Substance [49]
CD99 antigen (CD99) OTPUZ5DE CD99_HUMAN Affects Response To Substance [49]
Large ribosomal subunit protein uL23 (RPL23A) OTPYLCCX RL23A_HUMAN Affects Response To Substance [49]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) OTPYQX3K C1QBP_HUMAN Decreases Response To Substance [131]
Bone morphogenetic protein 4 (BMP4) OTPZMDFH BMP4_HUMAN Decreases Response To Substance [91]
Inosine triphosphate pyrophosphatase (ITPA) OTQ47WVR ITPA_HUMAN Affects Response To Substance [132]
45 kDa calcium-binding protein (SDF4) OTQ7WFYW CAB45_HUMAN Affects Response To Substance [49]
Eukaryotic translation initiation factor 5A-1 (EIF5A) OTQ8DJX5 IF5A1_HUMAN Affects Response To Substance [49]
Lactadherin (MFGE8) OTQKE41R MFGM_HUMAN Affects Response To Substance [49]
Calsyntenin-1 (CLSTN1) OTQN35G2 CSTN1_HUMAN Affects Response To Substance [49]
Histone deacetylase 4 (HDAC4) OTQNGD32 HDAC4_HUMAN Affects Response To Substance [49]
Double-stranded RNA-specific adenosine deaminase (ADAR) OTQNOHR8 DSRAD_HUMAN Decreases Response To Substance [133]
Keratin, type I cytoskeletal 23 (KRT23) OTQW6UAG K1C23_HUMAN Increases Response To Substance [50]
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) OTR443C5 BGH3_HUMAN Decreases Response To Substance [50]
Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2) OTR99SJ8 CDKA2_HUMAN Affects Response To Substance [49]
TNFAIP3-interacting protein 1 (TNIP1) OTRAOTEW TNIP1_HUMAN Affects Response To Substance [122]
Diamine oxidase (AOC1) OTRC220K AOC1_HUMAN Affects Response To Substance [49]
Dickkopf-related protein 1 (DKK1) OTRDLUSP DKK1_HUMAN Decreases Response To Substance [119]
Methyl-CpG-binding domain protein 3 (MBD3) OTRL76H5 MBD3_HUMAN Affects Response To Substance [49]
Gamma-enolase (ENO2) OTRODL0T ENOG_HUMAN Decreases Response To Substance [75]
Dr1-associated corepressor (DRAP1) OTRWLF6D NC2A_HUMAN Affects Response To Substance [49]
Glutathione S-transferase Mu 1 (GSTM1) OTSBF2MO GSTM1_HUMAN Decreases Response To Substance [130]
Protein kinase C delta type (PRKCD) OTSEH90E KPCD_HUMAN Affects Response To Substance [122]
Formin-binding protein 1 (FNBP1) OTSJ5KKA FNBP1_HUMAN Affects Response To Substance [49]
Lumican (LUM) OTSRC874 LUM_HUMAN Decreases Response To Substance [50]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Decreases Response To Substance [50]
Mesothelin (MSLN) OTT23UM3 MSLN_HUMAN Affects Response To Substance [49]
NKG2-C type II integral membrane protein (KLRC2) OTT4N86S NKG2C_HUMAN Affects Response To Substance [49]
Talin-1 (TLN1) OTTD2YXM TLN1_HUMAN Affects Response To Substance [49]
Collagen alpha-1(XV) chain (COL15A1) OTTFKK18 COFA1_HUMAN Decreases Response To Substance [50]
Adipogenesis regulatory factor (ADIRF) OTTJP8D4 ADIRF_HUMAN Affects Response To Substance [49]
CASP8-associated protein 2 (CASP8AP2) OTTWT68S C8AP2_HUMAN Increases Response To Substance [122]
Rab11 family-interacting protein 2 (RAB11FIP2) OTTX9RWE RFIP2_HUMAN Affects Response To Substance [49]
Protein disulfide-isomerase (P4HB) OTTYNYPF PDIA1_HUMAN Affects Response To Substance [49]
AMP deaminase 1 (AMPD1) OTU17BCI AMPD1_HUMAN Affects Response To Substance [132]
Period circadian protein homolog 2 (PER2) OTU2B1DJ PER2_HUMAN Affects Response To Substance [49]
Methylenetetrahydrofolate reductase (MTHFR) OTUBJSR7 MTHR_HUMAN Increases ADR [134]
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) OTUE7Z91 MP2K2_HUMAN Affects Response To Substance [49]
Prosaposin (PSAP) OTUOEKY7 SAP_HUMAN Affects Response To Substance [49]
AT-rich interactive domain-containing protein 5B (ARID5B) OTUQ4CQY ARI5B_HUMAN Affects Abundance [135]
Acyl-CoA 6-desaturase (FADS2) OTUX531P FADS2_HUMAN Affects Response To Substance [49]
Guanidinoacetate N-methyltransferase (GAMT) OTVC87ES GAMT_HUMAN Affects Response To Substance [49]
Matrilin-2 (MATN2) OTVDR68G MATN2_HUMAN Decreases Response To Substance [50]
Membralin (TMEM259) OTVH9HD8 MBRL_HUMAN Affects Response To Substance [49]
ATP-binding cassette sub-family C member 11 (ABCC11) OTVHL7OR MRP8_HUMAN Decreases Abundance [68]
Nicotinamide phosphoribosyltransferase (NAMPT) OTVJR3GL NAMPT_HUMAN Affects Response To Substance [136]
GTPase NRas (NRAS) OTVQ1DG3 RASN_HUMAN Increases Response To Substance [123]
Ensconsin (MAP7) OTVSSJ33 MAP7_HUMAN Affects Response To Substance [49]
ATP-binding cassette sub-family A member 2 (ABCA2) OTVSYK0X ABCA2_HUMAN Decreases Response To Substance [125]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3) OTVT1Q25 B3GN3_HUMAN Affects Response To Substance [49]
E3 ubiquitin-protein ligase KCMF1 (KCMF1) OTVTKFAU KCMF1_HUMAN Affects Response To Substance [49]
PHD finger protein 10 (PHF10) OTWDR4EX PHF10_HUMAN Affects Response To Substance [49]
Decorin (DCN) OTWLJL7K PGS2_HUMAN Decreases Response To Substance [50]
Phosphatase and actin regulator 2 (PHACTR2) OTWMX2A8 PHAR2_HUMAN Affects Response To Substance [49]
Periostin (POSTN) OTWP62UA POSTN_HUMAN Decreases Response To Substance [50]
Bcl-2-related protein A1 (BCL2A1) OTWRYSNA B2LA1_HUMAN Decreases Response To Substance [122]
Glypican-3 (GPC3) OTWS8WSW GPC3_HUMAN Increases Response To Substance [50]
CD302 antigen (CD302) OTX580VU CD302_HUMAN Affects Response To Substance [49]
Arfaptin-1 (ARFIP1) OTXHWO6M ARFP1_HUMAN Affects Response To Substance [49]
Glutathione peroxidase 2 (GPX2) OTXI2NTI GPX2_HUMAN Affects Response To Substance [49]
Bifunctional glutamate/proline--tRNA ligase (EPRS1) OTXK0FLB SYEP_HUMAN Affects Response To Substance [49]
ATP synthase subunit delta, mitochondrial (ATP5F1D) OTXTAG2V ATPD_HUMAN Affects Response To Substance [49]
Carbamoyl-phosphate synthase , mitochondrial (CPS1) OTXV8NSR CPSM_HUMAN Affects Response To Substance [49]
Progranulin (GRN) OTXXSJ53 GRN_HUMAN Affects Response To Substance [49]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PIK3C2B) OTY2PROB P3C2B_HUMAN Affects Response To Substance [49]
Thymidine kinase, cytosolic (TK1) OTY5JFM1 KITH_HUMAN Increases ADR [51]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Increases Response To Substance [50]
Calreticulin (CALR) OTYD2TR1 CALR_HUMAN Affects Response To Substance [49]
Lysosome-associated membrane glycoprotein 1 (LAMP1) OTYE92QY LAMP1_HUMAN Increases ADR [51]
BTB/POZ domain-containing protein 3 (BTBD3) OTZ607YT BTBD3_HUMAN Affects Response To Substance [49]
Ena/VASP-like protein (EVL) OTZ8ZDNY EVL_HUMAN Affects Response To Substance [49]
Protein BTG2 (BTG2) OTZF6K1H BTG2_HUMAN Affects Response To Substance [122]
Aspartate aminotransferase, cytoplasmic (GOT1) OTZLM5UB AATC_HUMAN Increases ADR [51]
Lysine-specific demethylase 6A (KDM6A) OTZM3MJJ KDM6A_HUMAN Affects Response To Substance [49]
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Affects Response To Substance [49]
Drebrin (DBN1) OTZVKG8A DREB_HUMAN Affects Response To Substance [49]
------------------------------------------------------------------------------------
⏷ Show the Full List of 1626 DOT(s)

Test Results of This Drug Combination in Other Disease Systems

Indication DrugCom ID Cell Line Status REF
Anaplastic large cell lymphoma DCZBNDV SR Investigative [1]
------------------------------------------------------------------------------------

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7006).
3 Romidepsin FDA Label
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Methotrexate FDA Label
6 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 040632.
7 Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for ... Trials. 2015 Mar 4;16:77.
8 ClinicalTrials.gov (NCT04136366) The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy. U.S. National Institutes of Health.
9 ClinicalTrials.gov (NCT04352465) Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients. U.S. National Institutes of Health.
10 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034238)
11 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
12 Inhibition of transcription, expression, and secretion of the vascular epithelial growth factor in human epithelial endometriotic cells by romidepsin. Fertil Steril. 2011 Apr;95(5):1579-83. doi: 10.1016/j.fertnstert.2010.12.058. Epub 2011 Feb 4.
13 Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3. Arch Toxicol. 2022 Jan;96(1):177-193. doi: 10.1007/s00204-021-03174-1. Epub 2021 Oct 19.
14 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
15 Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma. Clin Cancer Res. 2009 Feb 15;15(4):1496-503.
16 A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03. Neuro Oncol. 2011 May;13(5):509-16.
17 Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma. Clin Cancer Res. 2009 Feb 15;15(4):1496-503.
18 FDA Label of Romidepsin. The 2020 official website of the U.S. Food and Drug Administration.
19 Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines. J Pharmacol Exp Ther. 2005 Jul;314(1):467-75. doi: 10.1124/jpet.105.083956. Epub 2005 Apr 15.
20 Aberrant promoter methylation of the ABCG2 gene in renal carcinoma. Mol Cell Biol. 2006 Nov;26(22):8572-85.
21 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer). Biochem Biophys Res Commun. 2006 Dec 15;351(2):455-61. doi: 10.1016/j.bbrc.2006.10.055. Epub 2006 Oct 18.
22 Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res. 2006 Jul 15;66(14):7317-25. doi: 10.1158/0008-5472.CAN-06-0680.
23 Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells. Int J Cancer. 2004 Jun 10;110(2):301-8. doi: 10.1002/ijc.20117.
24 A sequential treatment of depsipeptide followed by 5-azacytidine enhances Gadd45beta expression in hepatocellular carcinoma cells. Anticancer Res. 2007 Nov-Dec;27(6B):3783-9.
25 Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells. Clin Cancer Res. 2004 Mar 1;10(5):1813-25. doi: 10.1158/1078-0432.ccr-0901-3.
26 Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells. Clin Cancer Res. 2008 Jan 15;14(2):549-58. doi: 10.1158/1078-0432.CCR-07-1934.
27 Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. Oncotarget. 2016 Oct 25;7(43):69804-69815. doi: 10.18632/oncotarget.12001.
28 Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells. Blood. 2006 Feb 15;107(4):1546-54. doi: 10.1182/blood-2004-10-4126. Epub 2005 Oct 13.
29 Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors. Int J Cancer. 2005 Sep 20;116(5):784-92. doi: 10.1002/ijc.21069.
30 Enhanced transgene expression in urothelial cancer gene therapy with histone deacetylase inhibitor. J Urol. 2005 Aug;174(2):747-52. doi: 10.1097/01.ju.0000164723.20555.e6.
31 Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. Endocr Relat Cancer. 2006 Sep;13(3):797-826. doi: 10.1677/erc.1.01143.
32 Identification of cytochrome P450 enzymes involved in the metabolism of FK228, a potent histone deacetylase inhibitor, in human liver microsomes. Biol Pharm Bull. 2005 Jan;28(1):124-9.
33 Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells. Int J Cancer. 2006 Jan 1;118(1):90-7. doi: 10.1002/ijc.21297.
34 Thymidylate synthase pharmacogenetics. Invest New Drugs. 2005 Dec;23(6):533-7. doi: 10.1007/s10637-005-4021-7.
35 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
36 Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis Res Ther. 2009;11(1):R15.
37 UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate. Biochem Pharmacol. 2011 Jan 1;81(1):60-70.
38 Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. Tumour Biol. 2011 Oct;32(5):965-76.
39 Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014 Jan;66(1):15-23.
40 Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells. Eur J Pharmacol. 2014 Jun 5;732:60-7.
41 Proteomic identification of differentially expressed proteins associated with the multiple drug resistance in methotrexate-resistant human breast cancer cells. Int J Oncol. 2014 Jul;45(1):448-58.
42 Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling. Mutat Res. 2007 Jun 1;619(1-2):16-29. doi: 10.1016/j.mrfmmm.2006.12.007. Epub 2007 Feb 8.
43 Effects of methotrexate on vascular endothelial growth factor, angiopoietin 1, and angiopoietin 2 in nasal polyps. Am J Rhinol Allergy. 2011 Jul-Aug;25(4):e129-32. doi: 10.2500/ajra.2011.25.3618.
44 Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix. J Nutr Biochem. 2007 Aug;18(8):541-52. doi: 10.1016/j.jnutbio.2006.11.002. Epub 2007 Feb 22.
45 Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation. Ann Rheum Dis. 2016 Feb;75(2):439-48. doi: 10.1136/annrheumdis-2014-206305. Epub 2015 Jan 9.
46 Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. J Biomol Screen. 2007 Apr;12(3):328-40. doi: 10.1177/1087057107299261. Epub 2007 Mar 22.
47 Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. Biomed Res Int. 2014;2014:616025. doi: 10.1155/2014/616025. Epub 2014 May 19.
48 Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
49 Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int J Cancer. 2006 Apr 1;118(7):1699-712. doi: 10.1002/ijc.21570.
50 Microarray-based detection and expression analysis of extracellular matrix proteins in drug?resistant ovarian cancer cell lines. Oncol Rep. 2014 Nov;32(5):1981-90. doi: 10.3892/or.2014.3468. Epub 2014 Sep 9.
51 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
52 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1213).
53 Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells. J Biol Chem. 1998 Apr 3;273(14):8106-11.
54 Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32.
55 Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models. Drug Metab Dispos. 2011 Nov;39(11):2155-61.
56 Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade. Cancer Lett. 2016 Jan 1;370(1):153-64.
57 Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res. 2003 Sep 1;63(17):5538-43.
58 Transport of organic anions across the basolateral membrane of proximal tubule cells. Rev Physiol Biochem Pharmacol. 2003;146:95-158.
59 Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo. Mol Pharm. 2015 Dec 7;12(12):4259-69.
60 Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. Biochemistry. 2003 May 13;42(18):5429-37.
61 Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport. J Pharmacol Exp Ther. 2007 Jan;320(1):229-35.
62 The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates. Cancer Res. 2005 May 15;65(10):4425-30.
63 Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate. Drug Metab Pharmacokinet. 2010;25(2):163-9.
64 Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3. Drug Metab Pharmacokinet. 2004 Oct;19(5):369-74.
65 Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71.
66 Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J Pharmacol Exp Ther. 2006 Aug;318(2):521-9.
67 LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology. 2001 Jun;120(7):1689-99.
68 ABCC11/MRP8 confers pemetrexed resistance in lung cancer. Cancer Sci. 2010 Nov;101(11):2404-10.
69 Biology of the major facilitative folate transporters SLC19A1 and SLC46A1. Curr Top Membr. 2014;73:175-204.
70 Site-specific contribution of proton-coupled folate transporter/haem carrier protein 1 in the intestinal absorption of methotrexate in rats. J Pharm Pharmacol. 2009 Jul;61(7):911-8.
71 Genetics of rheumatoid arthritis. Mayo Clin Proc. 2006 Jan;81(1):94-101.
72 The pharmacogenetics of methotrexate. Rheumatology (Oxford). 2007 Oct;46(10):1520-4.
73 Understanding and managing methotrexate nephrotoxicity. Oncologist. 2006 Jun;11(6):694-703.
74 Methotrexate normalizes up-regulated folate pathway genes in rheumatoid arthritis. Arthritis Rheum. 2013 Nov;65(11):2791-802.
75 Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells. BMC Med Genomics. 2008 Aug 11;1:35. doi: 10.1186/1755-8794-1-35.
76 Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells. Cell Physiol Biochem. 2007;20(6):967-76.
77 SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. Toxicol Sci. 2014 Nov;142(1):196-209. doi: 10.1093/toxsci/kfu162. Epub 2014 Aug 14.
78 The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line. Mol Cancer Ther. 2006 Feb;5(2):438-49. doi: 10.1158/1535-7163.MCT-05-0243.
79 P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate. Toxicol Appl Pharmacol. 2016 Sep 1;306:27-35. doi: 10.1016/j.taap.2016.06.030. Epub 2016 Jul 1.
80 Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis. Biochem Pharmacol. 2009 Apr 15;77(8):1410-7.
81 Methotrexate induction of human sulfotransferases in Hep G2 and Caco-2 cells. J Appl Toxicol. 2005 Sep-Oct;25(5):354-60.
82 Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1. Protein J. 2005 Feb;24(2):65-77.
83 Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug Metab Dispos. 2006 Oct;34(10):1742-8.
84 Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis Rheum. 2008 Dec;58(12):3675-83.
85 Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo. Mol Med. 2012 May 9;18:423-32.
86 Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance. Exp Cell Res. 2012 Jun 10;318(10):1146-59.
87 Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate. J Rheumatol. 2007 Sep;34(9):1817-22. Epub 2007 Aug 1.
88 Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kappaB, osteoprotegerin, and receptor activator of nuclear factor kappaB ligand. Arthritis Rheum. 2004 Dec;50(12):3831-43. doi: 10.1002/art.20637.
89 Distinct genetic profile in peripheral blood mononuclear cells of psoriatic arthritis patients treated with methotrexate and TNF-inhibitors. Clin Rheumatol. 2014 Dec;33(12):1815-21. doi: 10.1007/s10067-014-2807-8. Epub 2014 Oct 24.
90 Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway. Toxicology. 2009 Feb 27;256(3):183-90. doi: 10.1016/j.tox.2008.11.016. Epub 2008 Nov 28.
91 Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness. J Rheumatol. 2010 Feb;37(2):246-56. doi: 10.3899/jrheum.090167. Epub 2009 Dec 15.
92 Development of an alternative zebrafish model for drug-induced intestinal toxicity. J Appl Toxicol. 2018 Feb;38(2):259-273. doi: 10.1002/jat.3520. Epub 2017 Oct 13.
93 Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937. Arthritis Res Ther. 2014 Jan 20;16(1):R17. doi: 10.1186/ar4444.
94 [Increased secretion of vasopressin and edema formation in high dosage methotrexate therapy]. Z Gesamte Inn Med. 1988 Aug 1;43(15):411-4.
95 Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate. Arthritis Rheum. 2004 Oct;50(10):3286-95. doi: 10.1002/art.20518.
96 Editor's Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues. Toxicol Sci. 2016 Dec;154(2):354-367. doi: 10.1093/toxsci/kfw169. Epub 2016 Sep 7.
97 Association of cell cycle arrest with anticancer drug-induced epithelial-mesenchymal transition in alveolar epithelial cells. Toxicology. 2019 Aug 1;424:152231. doi: 10.1016/j.tox.2019.06.002. Epub 2019 Jun 4.
98 [Regulation mechanism of autophagy-related protein LC3 by c-Jun in methotrexate resistant human choriocarcinoma JEG-3 cells]. Zhonghua Fu Chan Ke Za Zhi. 2014 Jul;49(7):531-5.
99 Methotrexate-related response on human peripheral blood mononuclear cells may be modulated by the Ala16Val-SOD2 gene polymorphism. PLoS One. 2014 Oct 20;9(10):e107299. doi: 10.1371/journal.pone.0107299. eCollection 2014.
100 [Early neurotoxicity of high-dose of methotrexate and tetrahydrobiopterin deficiency]. Arch Fr Pediatr. 1991 Dec;48(10):719-22.
101 Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells. Clin Exp Immunol. 2007 May;148(2):288-95. doi: 10.1111/j.1365-2249.2007.03335.x. Epub 2007 Feb 7.
102 Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation. J Cell Biochem. 2006 Sep 1;99(1):146-55. doi: 10.1002/jcb.20908.
103 Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. Arthritis Res Ther. 2006;8(6):R169. doi: 10.1186/ar2078.
104 Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells. Biol Chem. 2006 Dec;387(12):1629-33. doi: 10.1515/BC.2006.203.
105 The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces. Br J Haematol. 2003 Jan;120(2):315-24. doi: 10.1046/j.1365-2141.2003.03971.x.
106 Enhancement of methotrexate nephrotoxicity after cisplatin therapy. Cancer. 1986 Dec 15;58(12):2617-21. doi: 10.1002/1097-0142(19861215)58:12<2617::aid-cncr2820581211>3.0.co;2-b.
107 Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2. Biochem Pharmacol. 2011 Feb 15;81(4):510-7. doi: 10.1016/j.bcp.2010.11.014. Epub 2010 Nov 27.
108 Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14.
109 Increased matrix proteins, collagen and transforming growth factor are early markers of hepatotoxicity in patients on long-term methotrexate therapy. J Toxicol Clin Toxicol. 1996;34(3):301-5. doi: 10.3109/15563659609013794.
110 A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate. Cancer Gene Ther. 2008 Sep;15(9):576-90. doi: 10.1038/cgt.2008.28. Epub 2008 May 16.
111 Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action. Arthritis Res Ther. 2012 Jun 8;14(3):R138. doi: 10.1186/ar3871.
112 The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis. Clin Exp Rheumatol. 2011 Nov-Dec;29(6):963-9. Epub 2011 Dec 22.
113 Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis. Mol Immunol. 2009 Oct;46(16):3345-57. doi: 10.1016/j.molimm.2009.07.019. Epub 2009 Sep 3.
114 The in vitro and in vivo anti-tumor effects of MTX-Fe3O 4-PLLA-PEG-PLLA microspheres prepared by suspension-enhanced dispersion by supercritical CO2. Sci China Life Sci. 2014 Jul;57(7):698-709. doi: 10.1007/s11427-014-4680-8. Epub 2014 Jun 16.
115 Methotrexate increases expression of cell cycle checkpoint genes via JNK activation. Arthritis Rheum. 2012 Jun;64(6):1780-9. doi: 10.1002/art.34342. Epub 2011 Dec 19.
116 Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone. Eur J Pharmacol. 2005 Dec 28;528(1-3):27-36. doi: 10.1016/j.ejphar.2005.10.068.
117 [Expression and function of Ahi-1 gene in Jurkat cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Apr;17(2):445-9.
118 Effect of doxorubicin, oxaliplatin, and methotrexate administration on the transcriptional activity of BCL-2 family gene members in stomach cancer cells. Cancer Biol Ther. 2013 Jul;14(7):587-96. doi: 10.4161/cbt.24591. Epub 2013 May 10.
119 Networking of differentially expressed genes in human cancer cells resistant to methotrexate. Genome Med. 2009 Sep 4;1(9):83. doi: 10.1186/gm83.
120 ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2. Biochem Cell Biol. 2006 Apr;84(2):199-206. doi: 10.1139/o05-173.
121 MTX-induced white matter changes are associated with polymorphisms of methionine metabolism. Neurology. 2005 Mar 8;64(5):912-3. doi: 10.1212/01.WNL.0000152840.26156.74.
122 Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX plus tumor necrosis factor inhibitor combined therapy. J Rheumatol. 2012 Aug;39(8):1524-32. doi: 10.3899/jrheum.120092. Epub 2012 Jul 1.
123 KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells. Mol Cancer Ther. 2014 Jun;13(6):1611-24. doi: 10.1158/1535-7163.MCT-13-0649. Epub 2014 Mar 31.
124 Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth. Ann Hematol. 2014 Mar;93(3):485-492. doi: 10.1007/s00277-013-1939-2. Epub 2013 Oct 24.
125 Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia. Mol Cancer Ther. 2006 Aug;5(8):1986-94.
126 Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis. Am J Hematol. 2011 Jan;86(1):98-101. doi: 10.1002/ajh.21897.
127 Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. BMC Cancer. 2010 Jun 1;10:250. doi: 10.1186/1471-2407-10-250.
128 Proteomics study of open biopsy samples identifies peroxiredoxin 2 as a predictive biomarker of response to induction chemotherapy in osteosarcoma. J Proteomics. 2013 Oct 8;91:393-404. doi: 10.1016/j.jprot.2013.07.022. Epub 2013 Aug 2.
129 A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis Rheum. 2007 Jun;56(6):1765-75. doi: 10.1002/art.22640.
130 The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells. PLoS One. 2013 May 13;8(5):e63276. doi: 10.1371/journal.pone.0063276. Print 2013.
131 [Expression of C1QBP gene and its correlation with drug resistance in human resistance choriocarcinoma cell line]. Zhonghua Fu Chan Ke Za Zhi. 2014 Aug;49(8):616-20.
132 Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032.
133 A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. J Biol Chem. 2017 Mar 24;292(12):4873-4884.
134 Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival. Haematologica. 2007 Apr;92(4):478-85. doi: 10.3324/haematol.10587.
135 Associations of novel genetic variations in the folate-related and ARID5B genes with the pharmacokinetics and toxicity of high-dose methotrexate in paediatric acute lymphoblastic leukaemia. Br J Haematol. 2014 Aug;166(3):410-20.
136 Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro. Clin Transl Sci. 2016 Jun;9(3):149-57. doi: 10.1111/cts.12399. Epub 2016 May 11.