Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8BKU9)

Drug Name
Acitretin Drug Info
Synonyms
Acitretina; Acitretine; Acitretinum; Etretin; Isoacitretin; Isoetretin; Neotigason; Soriatane; TMMP; Acitretina [Spanish]; Acitretine [French]; Acitretinum [Latin]; Retinoid etretin; U0279; Ro 10-1670; Ro 13-7652; Soriatane (TN); Soriatane, Acitretin; Acitretin (USAN/INN); Acitretin [USAN:INN:BAN]; All-trans-Acitretin; Ro 10-1670/000; Ro-10-1670; Ro-13-7652; Ro-10-1670/000; All-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid; (2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid; (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid; (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 13-cis-Acitretin; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid; 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Indication
Disease Entry ICD 11 Status REF
Psoriasis vulgaris EA90 Approved [1]
Therapeutic Class
Keratolytic Agents
Cross-matching ID
PubChem CID
5284513
ChEBI ID
CHEBI:50173
CAS Number
CAS 55079-83-9
TTD Drug ID
DM8BKU9
VARIDT Drug ID
DR00827
ACDINA Drug ID
D00012

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Signal transducer and activator of transcription 3 (STAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Napabucasin DMDZ6Q3 Colorectal cancer 2B91.Z Phase 3 [8]
Golotimod DMKZN3A Immune System disease 4A01-4B41 Phase 2 [9]
NT219 DMOYS1N Solid tumour/cancer 2A00-2F9Z Phase 1/2 [10]
WP-1066 DMUGHWR Recurrent glioblastoma 2A00.00 Phase 1/2 [8]
Atiprimod DM84YEC Multiple myeloma 2A83 Phase 1/2 [11]
OPB-31121 DM6VGO3 Hepatocellular carcinoma 2C12.02 Phase 1/2 [12]
IMX-110 DMNHZS4 Solid tumour/cancer 2A00-2F9Z Phase 1/2 [8]
GLG-801 DMY1CP9 Chronic lymphocytic leukaemia 2A82.0 Phase 1/2 [8]
OPB-51602 DM760FA Solid tumour/cancer 2A00-2F9Z Phase 1 [13]
TAK-114 DMTXE19 Ulcerative colitis DD71 Phase 1 [14]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [15]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [6]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [16]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [17]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [18]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [19]
Ethacrynic acid DM60QMR Edema MG29 Approved [20]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [21]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [22]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [23]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Gefitinib DM15F0X Colon adenocarcinoma Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [27]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [28]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [29]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [28]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [30]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [33]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [34]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [35]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [36]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Verapamil DMA7PEW Angina pectoris BA40 Approved [38]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [39]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [40]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [41]
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Drug(s) Affected By Retinoic acid receptor RXR-alpha (RXRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Selenium DM25CGV N. A. N. A. Approved [44]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [49]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [49]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [51]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [41]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [53]
Gefitinib DM15F0X Colon adenocarcinoma Approved [54]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [57]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [58]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [59]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Epinephrine DM3KJBC Acute asthma CA23 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [65]
Fructose DM43AN2 Vomiting MD90 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [60]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [67]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [69]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [70]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [40]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [71]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [72]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [73]
Gefitinib DM15F0X Colon adenocarcinoma Approved [74]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [77]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [69]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [78]
Paclitaxel DMLB81S Breast carcinoma Approved [79]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [68]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [40]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [71]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [82]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [84]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [85]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [86]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [87]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [88]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [91]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Gefitinib DM15F0X Colon adenocarcinoma Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Epinephrine DM3KJBC Acute asthma CA23 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [95]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [19]
Fructose DM43AN2 Vomiting MD90 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [97]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [98]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [99]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [100]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [39]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [101]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [102]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [27]
Meloxicam DM2AR7L Arthritis FA20 Approved [103]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [104]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [33]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [91]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Verapamil DMA7PEW Angina pectoris BA40 Approved [38]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [60]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [101]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [106]
Meloxicam DM2AR7L Arthritis FA20 Approved [107]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [29]
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Drug(s) Affected By FAS-associated death domain protein (FADD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Selenium DM25CGV N. A. N. A. Approved [108]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [109]
Quercetin DM3NC4M Obesity 5B81 Approved [102]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [45]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [111]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [112]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [113]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [114]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [115]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [117]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Gefitinib DM15F0X Colon adenocarcinoma Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [118]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [27]
Selenium DM25CGV N. A. N. A. Approved [57]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Signal transducer and activator of transcription 3 (STAT3) TTH8FZW STAT3_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [4]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [5]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [5]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [6]
FAS-associated death domain protein (FADD) OTV7GFHH FADD_HUMAN Gene/Protein Processing [5]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [7]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Gene/Protein Processing [7]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Gene/Protein Processing [7]

References

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6 Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury. J Toxicol Sci. 2021;46(4):167-176. doi: 10.2131/jts.46.167.
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12 OPB-31121, a novel small molecular inhibitor, disrupts the JAK2/STAT3 pathway and exhibits an antitumor activity in gastric cancer cells. Cancer Lett. 2013 Jul 10;335(1):145-52.
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16 Anti-androgenic effect of 6-formylindolo[3,2-b]carbazole (FICZ) in LNCaP cells is mediated by the aryl hydrocarbon-androgen receptors cross-talk. Steroids. 2020 Jan;153:108508. doi: 10.1016/j.steroids.2019.108508. Epub 2019 Oct 3.
17 Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. Arch Toxicol. 2008 Dec;82(12):909-21.
18 Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density. J Bone Miner Res. 2005 Feb;20(2):232-9. doi: 10.1359/JBMR.041110. Epub 2004 Nov 16.
19 Increased sensitivity for troglitazone-induced cytotoxicity using a human in vitro co-culture model. Toxicol In Vitro. 2009 Oct;23(7):1387-95.
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21 Gene expression changes in human small airway epithelial cells exposed to Delta9-tetrahydrocannabinol. Toxicol Lett. 2005 Aug 14;158(2):95-107.
22 The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol. Arch Toxicol. 2013 Apr;87(4):633-43.
23 Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. Gastroenterology. 2004 Nov;127(5):1436-45.
24 Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma. Sci Rep. 2020 Nov 26;10(1):20622. doi: 10.1038/s41598-020-77674-y.
25 Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells. Chem Biol Interact. 2013 Apr 25;203(2):412-22. doi: 10.1016/j.cbi.2013.03.011. Epub 2013 Mar 22.
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28 The antidepressants imipramine, clomipramine, and citalopram induce apoptosis in human acute myeloid leukemia HL-60 cells via caspase-3 activation. J Biochem Mol Toxicol. 1999;13(6):338-47. doi: 10.1002/(sici)1099-0461(1999)13:6<338::aid-jbt8>3.0.co;2-7.
29 Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line. Clin Cancer Res. 2000 Mar;6(3):891-900.
30 Investigation of molecular mechanisms underlying the antiproliferative effects of colchicine against PC3 prostate cancer cells. Toxicol In Vitro. 2021 Jun;73:105138. doi: 10.1016/j.tiv.2021.105138. Epub 2021 Mar 6.
31 Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer. Mol Cancer Ther. 2005 Feb;4(2):291-304.
32 Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells. Clin Exp Immunol. 2007 May;148(2):288-95. doi: 10.1111/j.1365-2249.2007.03335.x. Epub 2007 Feb 7.
33 4.8% sevoflurane induces activation of autophagy in human neuroblastoma SH-SY5Y cells by the AMPK/mTOR signaling pathway. Neurotoxicology. 2022 May;90:256-264. doi: 10.1016/j.neuro.2022.04.008. Epub 2022 Apr 23.
34 Enhanced chemotherapeutic efficacy of docetaxel in human lung cancer cell line via GLUT1 inhibitor. J Biochem Mol Toxicol. 2023 Jun;37(6):e23348. doi: 10.1002/jbt.23348. Epub 2023 Mar 31.
35 Breast cancer cells response to the antineoplastic agents cisplatin, carboplatin, and doxorubicin at the mRNA expression levels of distinct apoptosis-related genes, including the new member, BCL2L12. Ann N Y Acad Sci. 2007 Jan;1095:35-44. doi: 10.1196/annals.1397.005.
36 Extracellular signal-regulated kinase activation and Bcl-2 downregulation mediate apoptosis after gemcitabine treatment partly via a p53-independent pathway. Eur J Pharmacol. 2004 Oct 19;502(3):169-83. doi: 10.1016/j.ejphar.2004.09.006.
37 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
38 Verapamil potentiates anti-glioblastoma efficacy of temozolomide by modulating apoptotic signaling. Toxicol In Vitro. 2018 Oct;52:306-313. doi: 10.1016/j.tiv.2018.07.001. Epub 2018 Jul 9.
39 Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis. Apoptosis. 2006 Sep;11(9):1545-59. doi: 10.1007/s10495-006-8764-1.
40 Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway. Toxicol Sci. 2014 Feb;137(2):404-15. doi: 10.1093/toxsci/kft254. Epub 2013 Nov 5.
41 -Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-B Signaling Pathway. J Biochem Mol Toxicol. 2016 Mar;30(3):148-57. doi: 10.1002/jbt.21773. Epub 2016 Jan 6.
42 Phthalates efficiently bind to human peroxisome proliferator activated receptor and retinoid X receptor , , subtypes: an in silico approach. J Appl Toxicol. 2014 Jul;34(7):754-65. doi: 10.1002/jat.2902. Epub 2013 Jul 11.
43 Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol Sci. 2010 Apr;114(2):193-203. doi: 10.1093/toxsci/kfp309. Epub 2009 Dec 31.
44 Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium. BMC Genomics. 2004 Aug 20;5(1):58. doi: 10.1186/1471-2164-5-58.
45 Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicol In Vitro. 2017 Mar;39:93-103.
46 Identification and characterization of the human retinoid X receptor alpha gene promoter. Gene. 2006 May 10;372:118-27. doi: 10.1016/j.gene.2005.12.027. Epub 2006 Mar 6.
47 Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. Environ Health Perspect. 2011 Aug;119(8):1142-8. doi: 10.1289/ehp.1002952. Epub 2011 May 4.
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