Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMD7Z3H)

Drug Name
Benzylcinnamate Drug Info
Cross-matching ID
PubChem CID
5273469
ChEBI ID
CHEBI:146174
CAS Number
CAS 103-41-3
TTD Drug ID
DMD7Z3H

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Monoamine oxidase type B (MAO-B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selegiline Hydrochloride DM3VR1L Parkinson disease 8A00.0 Approved [6]
Phenelzine DMHIDUE Depression 6A70-6A7Z Approved [7]
Tranylcypromine DMGB5RE Major depressive disorder 6A70.3 Approved [8]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [9]
Safinamide mesylate DM0J2ZT Parkinson disease 8A00.0 Approved [10]
Rasagiline DM3WKQ4 Parkinson disease 8A00.0 Approved [11]
Sulphadoxine DMZI2UF Malaria 1F40-1F45 Approved [12]
Pargyline DMM0HR1 Hypertension BA00-BA04 Approved [13]
Indeloxazine DMWO3N6 Dementia 6D80-6D86 Approved [14]
Budipine DMODHQI Migraine 8A80 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metallothionein-2 (MT2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [16]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [17]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [18]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [22]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [23]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [24]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [25]
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Drug(s) Affected By Metallothionein-1A (MT1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [16]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [2]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [26]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [27]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [29]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [2]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [2]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [30]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [31]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [32]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [33]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [34]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [35]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [36]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Ethacrynic acid DM60QMR Edema MG29 Approved [37]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [27]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [38]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [39]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [40]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [41]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [43]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [44]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [45]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [48]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [49]
Diazepam DM08E9O Alcohol withdrawal Approved [50]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [18]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [2]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [52]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [49]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [53]
Testosterone DM7HUNW Hot flushes GA30 Approved [54]
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Drug(s) Affected By Transcription factor MafF (MAFF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [41]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [2]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [57]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [60]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [61]
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Drug(s) Affected By Amine oxidase A (MAOA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [63]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [64]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
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Drug(s) Affected By Amine oxidase B (MAOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Selegiline DM6034S Major depressive disorder 6A70.3 Approved [71]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [28]
BENZYL BENZOATE DMDPYI5 Infestations of lice and scabies 1G00.Z Approved [3]
Linezolid DMGFPU2 Bacteremia 1A73 Approved [73]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [74]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [75]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [76]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [77]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [78]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [81]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [80]
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Drug(s) Affected By T-lymphocyte activation antigen CD86 (CD86)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [83]
Kanamycin DM2DMPO Bacteremia 1A73 Approved [84]
Methotrexate DM2TEOL Anterior urethra cancer Approved [85]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [87]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [84]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [88]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Monoamine oxidase type B (MAO-B) TTGP7BY AOFB_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [2]
Amine oxidase A (MAOA) OT8NIWMQ AOFA_HUMAN Gene/Protein Processing [3]
Amine oxidase B (MAOB) OTTDFM1O AOFB_HUMAN Gene/Protein Processing [3]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [2]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [4]
Metallothionein-1A (MT1A) OTKBH52X MT1A_HUMAN Gene/Protein Processing [2]
Metallothionein-2 (MT2A) OTHOACHD MT2_HUMAN Gene/Protein Processing [2]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Gene/Protein Processing [2]
T-lymphocyte activation antigen CD86 (CD86) OTJCSBPC CD86_HUMAN Gene/Protein Processing [5]
Thioredoxin OT6XU6VW THIO_HUMAN Gene/Protein Processing [2]

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85 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
86 Differential effects of statins on relevant functions of human monocyte-derived dendritic cells. J Leukoc Biol. 2006 Mar;79(3):529-38. doi: 10.1189/jlb.0205064. Epub 2005 Dec 30.
87 Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
88 Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes. Mol Endocrinol. 2005 Nov;19(11):2685-95.