Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZLBUO)

Drug Name
Lucanthone Drug Info
Synonyms
Lucanthon; Lucanthonum; Lucantona; Miracol; Nilodin; Scapuren; Tixantone; LUCANTHONE HYDROCHLORIDE; Lucanthone monohydrochloride; Miracil D; BW 57223; CBC 900139; DR-15771; Lucanthone [INN:BAN]; Lucanthonum [INN-Latin]; Lucantona [INN-Spanish]; 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one; 1-(2-diethylaminoethylamino)-4-methylthioxanthen-9-one; 1-[[2-(Diethylamino)ethyl]amino]-4-methylthioxanthone; 1-{[2-(Diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one; 9H-Thioxanthen-9-one, 1-((2-(diethylamino)ethyl)amino)-4-methyl-(9CI)
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
10180
ChEBI ID
CHEBI:51052
CAS Number
CAS 479-50-5
TTD Drug ID
DMZLBUO

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting DNA topoisomerase II (TOP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [4]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [5]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [4]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [6]
Idarubicin DMM0XGL Acute myelogenous leukaemia 2A41 Approved [4]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [4]
Lomefloxacin DMVRH9C Bacterial infection 1A00-1C4Z Approved [7]
Dexrazoxane DMD7X1O Breast cancer 2C60-2C65 Approved [4]
Podofilox DMT2EJP Condyloma 1A95 Approved [8]
Enoxacin DMYTE6L Acute gonococcal cervicitis Approved [9]
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Drug(s) Affected By Serine/threonine-protein kinase PLK4 (PLK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Paclitaxel DMLB81S Breast carcinoma Approved [17]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [18]
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Drug(s) Affected By Nuclear envelope integral membrane protein 1 (NEMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [22]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
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Drug(s) Affected By Citron Rho-interacting kinase (CIT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
Arsenic DMTL2Y1 N. A. N. A. Approved [28]
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Drug(s) Affected By Kinetochore protein NDC80 homolog (NDC80)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
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Drug(s) Affected By Aurora kinase A (AURKA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
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Drug(s) Affected By Calmegin (CLGN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [41]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [42]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [43]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Gefitinib DM15F0X Colon adenocarcinoma Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [45]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [46]
Etretinate DM2CZFA Keratosis ED56 Approved [47]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [48]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [50]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [51]
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Drug(s) Affected By D-3-phosphoglycerate dehydrogenase (PHGDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
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Drug(s) Affected By Protein regulator of cytokinesis 1 (PRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
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Drug(s) Affected By Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
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Drug(s) Affected By Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
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Drug(s) Affected By Hyaluronan mediated motility receptor (HMMR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
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Drug(s) Affected By Cell division control protein 45 homolog (CDC45)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
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Drug(s) Affected By G2/mitotic-specific cyclin-B2 (CCNB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [41]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 15 (TNFSF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Clozapine DMFC71L Schizophrenia 6A20 Approved [69]
Menthol DMG2KW7 Back pain ME84.Z Approved [70]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Arsenic DMTL2Y1 N. A. N. A. Approved [72]
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Drug(s) Affected By Kinesin-like protein KIF20A (KIF20A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
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Drug(s) Affected By Chromosome-associated kinesin KIF4A (KIF4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
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Drug(s) Affected By Claudin-1 (CLDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [77]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [42]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
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Drug(s) Affected By Cystatin-SN (CST1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [78]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [78]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [80]
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Drug(s) Affected By C-X-C motif chemokine 10 (CXCL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [82]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
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Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Etretinate DM2CZFA Keratosis ED56 Approved [89]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [90]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [91]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [94]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [95]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [96]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [97]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [98]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [99]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [100]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [83]
Ethacrynic acid DM60QMR Edema MG29 Approved [101]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [102]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [103]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [104]
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Drug(s) Affected By Histone H2A type 1-B/E (H2AC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
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Drug(s) Affected By Plasminogen activator inhibitor 2 (SERPINB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [114]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [42]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [116]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [117]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [118]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [120]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [122]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [122]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [123]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [125]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [126]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [127]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [128]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [129]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [130]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [131]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Selenium DM25CGV N. A. N. A. Approved [132]
Etretinate DM2CZFA Keratosis ED56 Approved [47]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [133]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
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Drug(s) Affected By Cathepsin D (CTSD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [138]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [139]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Asparagine synthetase (ASNS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [142]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [142]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [143]
Fluoxetine DM3PD2C Bipolar depression Approved [142]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
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Drug(s) Affected By Cystatin-SA (CST2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
Drug(s) Affected By Histone H2A type 1 (H2AC11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [146]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [147]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [148]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [149]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [117]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [151]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [154]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myb-related protein B (MYBL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [157]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.4 (H1-4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [19]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [162]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA topoisomerase 2-alpha (TOP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [164]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [165]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [166]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [167]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [168]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A3 (ANXA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [170]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [170]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-interferon-inducible lysosomal thiol reductase (IFI30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [174]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [131]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [166]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Selenium DM25CGV N. A. N. A. Approved [132]
Etretinate DM2CZFA Keratosis ED56 Approved [47]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [175]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [176]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.5 (H1-5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [146]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.3 (H1-3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [180]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [182]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [11]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [183]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stathmin (STMN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Etretinate DM2CZFA Keratosis ED56 Approved [185]
Quercetin DM3NC4M Obesity 5B81 Approved [186]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [188]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [189]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [131]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [190]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [192]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [194]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon-induced GTP-binding protein Mx1 (MX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [196]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [174]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [197]
Testosterone enanthate DMB6871 N. A. N. A. Approved [198]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Filaggrin (FLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [200]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Folic Acid DMEMBJC Colorectal carcinoma Approved [201]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [202]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [200]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diamine acetyltransferase 1 (SAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Selenium DM25CGV N. A. N. A. Approved [195]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [204]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [205]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [205]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin alpha-3 (ITGA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Selenium DM25CGV N. A. N. A. Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Folic Acid DMEMBJC Colorectal carcinoma Approved [206]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group protein B2 (HMGB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dipeptidyl peptidase 4 (DPP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Saxagliptin DMGXENV Type-2 diabetes 5A11 Approved [210]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [211]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Alogliptin DM8WI3R Type-2 diabetes 5A11 Approved [212]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [213]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [214]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By M-phase inducer phosphatase 3 (CDC25C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [215]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [216]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [217]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [218]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanylate-binding protein 1 (GBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [219]
Selenium DM25CGV N. A. N. A. Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Testosterone enanthate DMB6871 N. A. N. A. Approved [198]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein kinase TTK (TTK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [222]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [223]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [224]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [225]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [226]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Breast cancer type 1 susceptibility protein (BRCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [227]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [228]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [133]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [229]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [230]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [231]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [166]
Gefitinib DM15F0X Colon adenocarcinoma Approved [44]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [232]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Etretinate DM2CZFA Keratosis ED56 Approved [47]
Prednisone DM2HG4X Acute asthma CA23 Approved [233]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [175]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
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Drug(s) Affected By Neutral amino acid transporter A (SLC1A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [234]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [215]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [53]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [215]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 4 group A member 2 (NR4A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [237]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [197]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proliferation marker protein Ki-67 (MKI67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [239]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [240]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [241]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [242]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [243]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chemerin-like receptor 2 (CMKLR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [244]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [244]
Arsenic DMTL2Y1 N. A. N. A. Approved [28]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [245]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [246]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [247]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue factor pathway inhibitor 2 (TFPI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCN family member 3 (CCN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [190]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [249]
Arsenic DMTL2Y1 N. A. N. A. Approved [72]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [250]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [190]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H3-like centromeric protein A (CENPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein F (CENPF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA primase small subunit (PRIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication ATP-dependent helicase/nuclease DNA2 (DNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Breast cancer type 2 susceptibility protein (BRCA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [229]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [253]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase Nek2 (NEK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Selenium DM25CGV N. A. N. A. Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF11 (KIF11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK1 (PLK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [254]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RecQ-like DNA helicase BLM (BLM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase epsilon subunit 2 (POLE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [61]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinases regulatory subunit 1 (CKS1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [255]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [256]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [257]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin, aortic smooth muscle (ACTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [258]
Quercetin DM3NC4M Obesity 5B81 Approved [259]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Panobinostat DM58WKG Chronic graft versus host disease Approved [260]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [261]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [262]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [263]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H4 (H4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Selenium DM25CGV N. A. N. A. Approved [195]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Panobinostat DM58WKG Chronic graft versus host disease Approved [264]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2B type 1-C/E/F/G/I (H2BC10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Ethanol DMDRQZU Chronic pain MG30 Approved [266]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H3.1 (H3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pregnancy-specific beta-1-glycoprotein 9 (PSG9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Arsenic DMTL2Y1 N. A. N. A. Approved [28]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
SB-431542 DM0YOXQ Pulmonary fibrosis CB03.4 Preclinical [267]
Drug(s) Affected By Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [268]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [269]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [269]
Quercetin DM3NC4M Obesity 5B81 Approved [270]
Fluoxetine DM3PD2C Bipolar depression Approved [269]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [271]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere-associated protein E (CENPE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF23 (KIF23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [273]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA repair protein RAD51 homolog 1 (RAD51)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [274]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [275]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [276]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Quizartinib DM8Y4JS Acute myeloid leukaemia 2A60 Approved [277]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prolow-density lipoprotein receptor-related protein 1 (LRP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [265]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [278]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [279]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Forkhead box protein M1 (FOXM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Quercetin DM3NC4M Obesity 5B81 Approved [282]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [283]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [38]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [38]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division cycle protein 20 homolog (CDC20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [284]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-24 (IL24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [152]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [152]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [152]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [285]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pregnancy-specific beta-1-glycoprotein 7 (PSG7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Liothyronine DM6IR3P Congenital hypothyroidism Approved [286]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [287]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
Milchsaure DM462BT Pruritus EC90 Investigative [288]
Drug(s) Affected By Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [282]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [270]
Fluoxetine DM3PD2C Bipolar depression Approved [289]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [271]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [290]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-18 (IL18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [291]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [293]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [294]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [296]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [297]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [296]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Separin (ESPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Folic Acid DMEMBJC Colorectal carcinoma Approved [201]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Maternal embryonic leucine zipper kinase (MELK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF22 (KIF22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Bortezomib DMNO38U Leukemia Approved [22]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [214]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [298]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane glycoprotein NMB (GPNMB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 2 (NCAPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Haloperidol DM96SE0 Delirium Approved [268]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PCNA-associated factor (PCLAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [299]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF14 (KIF14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pregnancy-specific beta-1-glycoprotein 5 (PSG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [300]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [245]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
Drug(s) Affected By Delta(24)-sterol reductase (DHCR24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [195]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [301]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Fluoxetine DM3PD2C Bipolar depression Approved [289]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [302]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [213]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disks large-associated protein 5 (DLGAP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Methylsterol monooxygenase 1 (MSMO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Fluoxetine DM3PD2C Bipolar depression Approved [289]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [271]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [173]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone-lysine N-methyltransferase EZH2 (EZH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [303]
Quercetin DM3NC4M Obesity 5B81 Approved [240]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [304]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [305]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [306]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 3 (CDKN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [41]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA excision repair protein ERCC-6-like (ERCC6L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [307]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromosome-associated kinesin KIF4B (KIF4B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [80]
Drug(s) Affected By Inactive Rho GTPase-activating protein 11B (ARHGAP11B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [80]
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Drug(s) Affected By Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Indomethacin DMSC4A7 Bursitis Approved [310]
Arsenic DMTL2Y1 N. A. N. A. Approved [28]
Mitotane DMU1GX0 Adrenocortical carcinoma 2D11.Z Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centrosomal protein of 55 kDa (CEP55)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ethanol DMDRQZU Chronic pain MG30 Approved [312]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Quinone oxidoreductase PIG3 (TP53I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [313]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [314]
Amifostine DM5FL14 Mucositis CA00 Approved [315]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [316]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Shugoshin 2 (SGO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-acetyltransferase ESCO2 (ESCO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [22]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Shugoshin 1 (SGO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [307]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [183]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DEP domain-containing protein 1A (DEPDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein lin-9 homolog (LIN9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ethanol DMDRQZU Chronic pain MG30 Approved [318]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM72A (FAM72A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [80]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [319]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [320]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Cell division cycle-associated protein 2 (CDCA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [215]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial fission regulator 2 (MTFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho GTPase-activating protein 11A (ARHGAP11A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATPase family AAA domain-containing protein 2 (ATAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SHC-transforming protein 4 (SHC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [323]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [324]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [325]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [326]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysophospholipid acyltransferase 1 (MBOAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [327]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [328]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [246]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [40]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [329]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [324]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Patched domain-containing protein 4 (PTCHD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [330]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [331]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [221]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [246]
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H3.2 (H3C13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [332]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [333]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [332]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [298]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [334]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein U (CENPU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein MCM10 homolog (MCM10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein mono-ADP-ribosyltransferase TIPARP (TIPARP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucosylceramide transporter ABCA12 (ABCA12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras GTPase-activating-like protein IQGAP3 (IQGAP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [307]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin-2 complex subunit G2 (NCAPG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [146]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2A type 2-B (H2AC21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [80]
Milchsaure DM462BT Pruritus EC90 Investigative [288]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Dynein axonemal intermediate chain 3 (DNAI3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [53]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [53]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [323]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [247]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Extracellular sulfatase Sulf-2 (SULF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [265]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [53]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Signal peptide, CUB and EGF-like domain-containing protein 1 (SCUBE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [246]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Drug(s) Affected By Cytoskeleton-associated protein 2-like (CKAP2L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [249]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase TRIM22 (TRIM22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [335]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Ethanol DMDRQZU Chronic pain MG30 Approved [318]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [22]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Abnormal spindle-like microcephaly-associated protein (ASPM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [146]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [273]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein L (CENPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Arsenic DMTL2Y1 N. A. N. A. Approved [336]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [183]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By T-complex protein 11-like protein 2 (TCP11L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [337]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Holliday junction recognition protein (HJURP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Methamphetamine DMPM4SK Anxiety Approved [338]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [339]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SHC SH2 domain-binding protein 1 (SHCBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinetochore scaffold 1 (KNL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondria-eating protein (SPATA18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [340]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [340]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [244]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein CIP2A (CIP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [307]
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Drug(s) Affected By Probable glutathione peroxidase 8 (GPX8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [213]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Orlistat DMRJSP8 Obesity 5B81 Approved [341]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [342]
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Drug(s) Affected By DEP domain-containing protein 1B (DEPDC1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Panobinostat DM58WKG Chronic graft versus host disease Approved [40]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
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Drug(s) Affected By Secreted and transmembrane protein 1 (SECTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [265]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [343]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [163]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [344]
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Drug(s) Affected By Aquaporin-3 (AQP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [345]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [346]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ampicillin DMHWE7P Acute epiglottitis Approved [20]
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Drug(s) Affected By Peroxidasin homolog (PXDN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [95]
Testosterone enanthate DMB6871 N. A. N. A. Approved [198]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [347]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [348]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [349]
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Drug(s) Affected By Centromere protein I (CENPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Folic Acid DMEMBJC Colorectal carcinoma Approved [201]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [22]
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Drug(s) Affected By Histone H2B type 1-H (H2BC9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [350]
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Drug(s) Affected By Tumor protein p53-inducible nuclear protein 1 (TP53INP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [351]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [53]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
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Drug(s) Affected By RAD51-associated protein 1 (RAD51AP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exosome complex component RRP43 (EXOSC8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [19]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
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Drug(s) Affected By Ubiquitin thioesterase OTUB2 (OTUB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Urethane DM7NSI0 N. A. N. A. Phase 4 [308]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [352]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [353]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [354]
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Drug(s) Affected By Protein Spindly (SPDL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
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Drug(s) Affected By Molybdenum cofactor sulfurase (MOCOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [221]
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Drug(s) Affected By Aurora kinase B (AURKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
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Drug(s) Affected By Proline-rich protein 11 (PRR11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [355]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
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Drug(s) Affected By Lymphokine-activated killer T-cell-originated protein kinase (PBK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [356]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
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Drug(s) Affected By Histone H2A type 1-H (H2AC12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [357]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Ethanol DMDRQZU Chronic pain MG30 Approved [266]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [323]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [333]
Berberine DMC5Q8X N. A. N. A. Phase 4 [358]
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Drug(s) Affected By Uncharacterized protein C5orf34 (C5ORF34)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
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Drug(s) Affected By Kinesin-like protein KIF20B (KIF20B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [282]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [359]
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Drug(s) Affected By Sperm-associated antigen 5 (SPAG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
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Drug(s) Affected By Kinesin-like protein KIF2C (KIF2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [360]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
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Drug(s) Affected By Cell division control protein 6 homolog (CDC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Quercetin DM3NC4M Obesity 5B81 Approved [282]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
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Drug(s) Affected By Histone H2A type 1-J (H2AC14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [283]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [144]
Berberine DMC5Q8X N. A. N. A. Phase 4 [358]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [362]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [248]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [363]
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Drug(s) Affected By Histone H2B type 1-M (H2BC14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [95]
Ethanol DMDRQZU Chronic pain MG30 Approved [266]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [181]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Berberine DMC5Q8X N. A. N. A. Phase 4 [358]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [309]
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Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [282]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [364]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [365]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [256]
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Drug(s) Affected By Condensin complex subunit 3 (NCAPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
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Drug(s) Affected By Centromere protein K (CENPK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
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Drug(s) Affected By Latexin (LXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [366]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [203]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [283]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [38]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [38]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIFC1 (KIFC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Meiotic nuclear division protein 1 homolog (MND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [27]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding protein 2 (GTPBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [174]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [22]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [367]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [317]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [14]
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Drug(s) Affected By Nucleolar and spindle-associated protein 1 (NUSAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
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Drug(s) Affected By Kinetochore protein Nuf2 (NUF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
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Drug(s) Affected By Protein Niban 1 (NIBAN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [368]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [171]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [42]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [369]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Ethanol DMDRQZU Chronic pain MG30 Approved [318]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rac GTPase-activating protein 1 (RACGAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [34]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [41]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein ECT2 (ECT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Testosterone enanthate DMB6871 N. A. N. A. Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinetochore protein Spc25 (SPC25)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
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Drug(s) Affected By Anillin (ANLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF15 (KIF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein diaphanous homolog 3 (DIAPH3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [33]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Structural maintenance of chromosomes protein 4 (SMC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [41]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fanconi anemia group I protein (FANCI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [370]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 45A (TMEM45A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [53]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [371]
Arsenic DMTL2Y1 N. A. N. A. Approved [372]
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Drug(s) Affected By Denticleless protein homolog (DTL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [373]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
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Drug(s) Affected By Homologous-pairing protein 2 homolog (PSMC3IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [299]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [73]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
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Drug(s) Affected By DNA helicase MCM8 (MCM8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [374]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 5 (FBXO5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [145]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
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Drug(s) Affected By Targeting protein for Xklp2 (TPX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [26]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exonuclease 1 (EXO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [221]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [64]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-activated chloride channel regulator 2 (CLCA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [375]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [376]
Drug(s) Affected By Lysosome-associated membrane glycoprotein 3 (LAMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [39]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [369]
Ethanol DMDRQZU Chronic pain MG30 Approved [318]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [108]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [367]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [367]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Origin recognition complex subunit 6 (ORC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [20]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoserine aminotransferase (PSAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [141]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [53]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [377]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA topoisomerase II (TOP2) TT0IHXV TOP2A_HUMAN; TOP2B_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Abnormal spindle-like microcephaly-associated protein (ASPM) OTKXQMNA ASPM_HUMAN Gene/Protein Processing [3]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [3]
Anillin (ANLN) OTXJY54C ANLN_HUMAN Gene/Protein Processing [3]
Annexin A3 (ANXA3) OTDD8OI7 ANXA3_HUMAN Gene/Protein Processing [3]
Aquaporin-3 (AQP3) OT2J7JPD AQP3_HUMAN Gene/Protein Processing [3]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Gene/Protein Processing [3]
ATPase family AAA domain-containing protein 2 (ATAD2) OT8MCRNY ATAD2_HUMAN Gene/Protein Processing [3]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Gene/Protein Processing [3]
Aurora kinase B (AURKB) OTIY4VHU AURKB_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [3]

References

1 Drug information of Lucanthone, 2008. eduDrugs.
2 Clonogenicity of human leukemic cells protected from cell-lethal agents by heat shock protein 70. Cell Stress Chaperones. 2005 Spring;10(1):37-45.
3 Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis. J Biol Chem. 2011 Feb 25;286(8):6602-13.
4 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
5 Etoposide, topoisomerase II and cancer.Curr Med Chem Anticancer Agents.2005 Jul;5(4):363-72.
6 Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells. Br J Haematol. 1998 Jan;100(1):142-6.
7 Inhibition of human topoisomerase IIalpha by fluoroquinolones and ultraviolet A irradiation. Toxicol Sci. 2002 Sep;69(1):16-22.
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