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Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes.Nat Genet. 2012 Dec;44(12):1310-5. doi: 10.1038/ng.2455. Epub 2012 Oct 28.
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| 2 |
An association between the Trp64Arg polymorphism in the beta3-adrenergic receptor gene and endometrial cancer and obesity.J Exp Clin Cancer Res. 2004 Dec;23(4):669-74.
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| 3 |
Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue.Chem Biol Interact. 2013 Feb 25;202(1-3):226-33. doi: 10.1016/j.cbi.2012.11.001. Epub 2012 Nov 9.
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| 4 |
Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.Cancer Cell. 2017 Dec 11;32(6):761-776.e6. doi: 10.1016/j.ccell.2017.11.006.
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| 5 |
Coordinate expression of Cdc25B and ER-alpha is frequent in low-grade endometrioid endometrial carcinoma but uncommon in high-grade endometrioid and nonendometrioid carcinomas.Cancer Res. 2003 Oct 1;63(19):6195-9.
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| 6 |
Targeting P16INK4A in uterine serous carcinoma through inhibition of histone demethylation.Oncol Rep. 2019 May;41(5):2667-2678. doi: 10.3892/or.2019.7067. Epub 2019 Mar 14.
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| 7 |
Transcriptional profiling endometrial carcinomas microdissected from DES-treated mice identifies changes in gene expression associated with estrogenic tumor promotion.Int J Cancer. 2006 Oct 15;119(8):1843-9. doi: 10.1002/ijc.22063.
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| 8 |
Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells.Mol Endocrinol. 2011 Nov;25(11):1892-903. doi: 10.1210/me.2011-1139. Epub 2011 Sep 8.
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| 9 |
Prognostic evaluation of epidermal fatty acid-binding protein and calcyphosine, two proteins implicated in endometrial cancer using a proteomic approach.Int J Cancer. 2008 Nov 15;123(10):2377-83. doi: 10.1002/ijc.23808.
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| 10 |
Regulation of tumor invasion by HOXB13 gene overexpressed in human endometrial cancer.Oncol Rep. 2005 Apr;13(4):721-6.
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| 11 |
Interaction of soy and 17beta-HSD1 gene polymorphisms in the risk of endometrial cancer.Pharmacogenet Genomics. 2007 Feb;17(2):161-7. doi: 10.1097/FPC.0b013e32801112a1.
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| 12 |
Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer.Chem Biol Interact. 2013 Feb 25;202(1-3):210-7. doi: 10.1016/j.cbi.2012.11.012. Epub 2012 Nov 27.
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| 13 |
A strategy for high-resolution protein identification in surface-enhanced laser desorption/ionization mass spectrometry: calgranulin A and chaperonin 10 as protein markers for endometrial carcinoma.Proteomics. 2005 May;5(7):1953-66. doi: 10.1002/pmic.200401059.
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| 14 |
Down-regulation of IGF-1R expression inhibits growth and enhances chemosensitivity of endometrial carcinoma in vitro.Mol Cell Biochem. 2011 Jul;353(1-2):225-33. doi: 10.1007/s11010-011-0790-9. Epub 2011 Mar 26.
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Loss of gamma-Catenin expression in squamous differentiation in endometrial carcinomas.Int J Gynecol Pathol. 2002 Jul;21(3):246-54. doi: 10.1097/00004347-200207000-00007.
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| 16 |
Blockage of intermediate-conductance-Ca(2+) -activated K(+) channels inhibits progression of human endometrial cancer.Oncogene. 2007 Aug 2;26(35):5107-14. doi: 10.1038/sj.onc.1210308. Epub 2007 Feb 19.
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Dietary folate intake, MTHFR genetic polymorphisms, and the risk of endometrial cancer among Chinese women.Cancer Epidemiol Biomarkers Prev. 2007 Feb;16(2):281-7. doi: 10.1158/1055-9965.EPI-06-0798.
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| 18 |
Expression of organic cation transporter SLC22A16 in human endometria.Int J Gynecol Pathol. 2007 Jan;26(1):53-60. doi: 10.1097/01.pgp.0000225845.67245.b3.
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| 19 |
Cyr61, a member of ccn (connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed) family, predicts survival of patients with endometrial cancer of endometrioid subtype.Gynecol Oncol. 2009 Jan;112(1):229-34. doi: 10.1016/j.ygyno.2008.09.039. Epub 2008 Nov 12.
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| 20 |
CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells.Oncogene. 2008 Apr 17;27(18):2513-24. doi: 10.1038/sj.onc.1210924. Epub 2007 Nov 5.
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| 21 |
Cytochrome P450 1B1 and catechol-O-methyltransferase polymorphisms and endometrial cancer susceptibility.Carcinogenesis. 2004 Apr;25(4):559-65. doi: 10.1093/carcin/bgh039. Epub 2003 Dec 4.
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| 22 |
AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer.Mol Cell Endocrinol. 2006 Mar 27;248(1-2):126-35. doi: 10.1016/j.mce.2005.10.009. Epub 2005 Dec 9.
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| 23 |
DNA methylation inhibits p53-mediated survivin repression. Oncogene. 2009 May 14;28(19):2046-50. doi: 10.1038/onc.2009.62. Epub 2009 Apr 13.
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| 24 |
The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture. Clin Exp Med. 2007 Mar;7(1):6-10. doi: 10.1007/s10238-007-0119-x.
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| 25 |
Loss of Cdh1 and Trp53 in the uterus induces chronic inflammation with modification of tumor microenvironment.Oncogene. 2015 May 7;34(19):2471-82. doi: 10.1038/onc.2014.193. Epub 2014 Jul 7.
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| 26 |
Cyclic changes in the expression of p57(kip2) in human endometrium and its regulation by steroid hormones in endometrial stromal cells in vitro. Reprod Sci. 2012 Jan;19(1):92-101. doi: 10.1177/1933719111414209. Epub 2011 Nov 7.
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Variants in hormone biosynthesis genes and risk of endometrial cancer.Cancer Causes Control. 2008 Nov;19(9):955-63. doi: 10.1007/s10552-008-9160-7. Epub 2008 Apr 25.
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The nuclear receptors SF1 and LRH1 are expressed in endometrial cancer cells and regulate steroidogenic gene transcription by cooperating with AP-1 factors. Cancer Lett. 2009 Mar 8;275(1):127-38.
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| 29 |
Endometrial Cancer Risk Factors, Hormone Receptors, and Mortality Prediction.Cancer Epidemiol Biomarkers Prev. 2017 May;26(5):727-735. doi: 10.1158/1055-9965.EPI-16-0821. Epub 2017 Jan 4.
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| 30 |
The endometrial cancer cell lines Ishikawa and HEC-1A, and the control cell line HIEEC, differ in expression of estrogen biosynthetic and metabolic genes, and in androstenedione and estrone-sulfate metabolism.Chem Biol Interact. 2015 Jun 5;234:309-19. doi: 10.1016/j.cbi.2014.11.015. Epub 2014 Nov 28.
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Prospective enterprise-level molecular genotyping of a cohort of cancer patients.J Mol Diagn. 2014 Nov;16(6):660-72. doi: 10.1016/j.jmoldx.2014.06.004. Epub 2014 Aug 23.
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Regulation of endometrial adenocarcinoma cell proliferation by Activin-A and its modulation by 17beta-estradiol.Mol Cell Endocrinol. 2002 Jun 28;192(1-2):187-95. doi: 10.1016/s0303-7207(01)00648-7.
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Long non-coding RNA LINC00672 contributes to p53 protein-mediated gene suppression and promotes endometrial cancer chemosensitivity. J Biol Chem. 2017 Apr 7;292(14):5801-5813. doi: 10.1074/jbc.M116.758508. Epub 2017 Feb 23.
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Epigenetic signatures of familial cancer are characteristic of tumor type and family category.Cancer Res. 2008 Jun 15;68(12):4597-605. doi: 10.1158/0008-5472.CAN-07-6645.
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| 35 |
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.Nat Genet. 2016 Feb;48(2):176-82. doi: 10.1038/ng.3470. Epub 2015 Dec 14.
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| 36 |
High levels of Nrf2 determine chemoresistance in type II endometrial cancer. Cancer Res. 2010 Jul 1;70(13):5486-96. doi: 10.1158/0008-5472.CAN-10-0713. Epub 2010 Jun 8.
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Tumour-suppression activity of the proapoptotic regulator Par4.EMBO Rep. 2005 Jun;6(6):577-83. doi: 10.1038/sj.embor.7400421.
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| 38 |
Identification of optimal reference genes for gene expression normalization in a wide cohort of endometrioid endometrial carcinoma tissues.PLoS One. 2014 Dec 4;9(12):e113781. doi: 10.1371/journal.pone.0113781. eCollection 2014.
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Emergence, involution, and progression to carcinoma of mutant clones in normal endometrial tissues.Cancer Res. 2014 May 15;74(10):2796-802. doi: 10.1158/0008-5472.CAN-14-0108. Epub 2014 Mar 24.
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| 40 |
RNF43 is frequently mutated in colorectal and endometrial cancers.Nat Genet. 2014 Dec;46(12):1264-6. doi: 10.1038/ng.3127. Epub 2014 Oct 26.
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| 41 |
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369.
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| 42 |
The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms. Eur J Cancer. 2010 Mar;46(4):836-50. doi: 10.1016/j.ejca.2009.12.025. Epub 2010 Jan 12.
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Emerging relationships between papillary proliferation of the endometrium and endometrial carcinoma: evidence from an immunohistochemical and molecular analysis.Virchows Arch. 2019 Aug;475(2):201-209. doi: 10.1007/s00428-019-02589-7. Epub 2019 May 12.
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Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors.Int J Cancer. 2004 Dec 20;112(6):959-66. doi: 10.1002/ijc.20524.
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| 45 |
CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility.Cancer. 2008 May 1;112(9):1964-73. doi: 10.1002/cncr.23392.
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| 46 |
A novel cancer testis antigen that is frequently expressed in pancreatic, lung, and endometrial cancers.Clin Cancer Res. 2006 Jan 1;12(1):191-7. doi: 10.1158/1078-0432.CCR-05-1206.
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| 47 |
Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.Cancer Genet Cytogenet. 2008 Jul;184(1):9-21. doi: 10.1016/j.cancergencyto.2008.02.016.
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Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer.Oncol Rep. 2007 Jan;17(1):41-8.
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| 49 |
Role of hyaluronan and hyaluronan synthase in endometrial cancer.Oncol Rep. 2005 Jun;13(6):1101-5.
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Multiple loci identified in a genome-wide association study of prostate cancer.Nat Genet. 2008 Mar;40(3):310-5. doi: 10.1038/ng.91. Epub 2008 Feb 10.
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| 51 |
The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.Nat Genet. 2016 Aug;48(8):848-55. doi: 10.1038/ng.3602. Epub 2016 Jun 27.
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Gain of OGP, an estrogen-regulated oviduct-specific glycoprotein, is associated with the development of endometrial hyperplasia and endometrial cancer.Clin Cancer Res. 2004 Dec 1;10(23):7958-64. doi: 10.1158/1078-0432.CCR-04-1261.
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Deregulation of estrogen receptor coactivator proline-, glutamic acid-, and leucine-rich protein-1/modulator of nongenomic activity of estrogen receptor in human endometrial tumors.J Clin Endocrinol Metab. 2004 Dec;89(12):6130-8. doi: 10.1210/jc.2004-0909.
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Endocrine gland-derived vascular endothelial growth factor is expressed in human peri-implantation endometrium, but not in endometrial carcinoma.Endocrinology. 2006 Jan;147(1):88-95. doi: 10.1210/en.2005-0543. Epub 2005 Oct 6.
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Expression of a retinol dehydrogenase (hRoDH-4), a member of the retinol/steroid dehydrogenase family implicated in retinoic acid biosynthesis, in normal and neoplastic endometria.Am J Obstet Gynecol. 2002 Apr;186(4):675-83. doi: 10.1067/mob.2002.122127.
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SIX1 Oncoprotein as a Biomarker in a Model of Hormonal Carcinogenesis and in Human Endometrial Cancer.Mol Cancer Res. 2016 Sep;14(9):849-58. doi: 10.1158/1541-7786.MCR-16-0084. Epub 2016 Jun 3.
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NSSR1 is regulated by testosterone in the mouse uterus and extensively expressed in endometrial carcinoma.Tumour Biol. 2011 Apr;32(2):359-66. doi: 10.1007/s13277-010-0128-3. Epub 2010 Nov 12.
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Imup-1 and imup-2 overexpression in endometrial carcinoma in Korean and Japanese populations.Anticancer Res. 2008 Mar-Apr;28(2A):865-71.
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| 59 |
CK2beta is expressed in endometrial carcinoma and has a role in apoptosis resistance and cell proliferation.Am J Pathol. 2009 Jan;174(1):287-96. doi: 10.2353/ajpath.2009.080552. Epub 2008 Dec 4.
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LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle.Oncogenesis. 2018 Jan 23;7(1):3. doi: 10.1038/s41389-017-0019-1.
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Infrequent Immunohistochemical Expression of Napsin A in Endometrial Carcinomas.Appl Immunohistochem Mol Morphol. 2017 Oct;25(9):632-638. doi: 10.1097/PAI.0000000000000350.
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Possible functions of CD169-positive sinus macrophages in lymph nodes in anti-tumor immune responses.Cancer Sci. 2017 Mar;108(3):290-295. doi: 10.1111/cas.13137. Epub 2017 Mar 7.
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Mammaglobin B expression in human endometrial cancer.Int J Gynecol Cancer. 2008 Sep-Oct;18(5):1090-6. doi: 10.1111/j.1525-1438.2007.01137.x. Epub 2007 Nov 16.
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Correlations between reduced expression of the metastasis suppressor gene KAI-1 and accumulation of p53 in uterine carcinomas and sarcomas.Virchows Arch. 2008 Jul;453(1):89-96. doi: 10.1007/s00428-008-0608-7. Epub 2008 Apr 16.
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Expression of receptor-binding cancer antigen expressed on SiSo cells and estrogen receptor subtypes in the normal, hyperplastic, and carcinomatous endometrium.Int J Gynecol Cancer. 2008 Jan-Feb;18(1):152-8. doi: 10.1111/j.1525-1438.2007.00966.x. Epub 2007 Apr 26.
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Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments.Mol Imaging Biol. 2013 Feb;15(1):68-78. doi: 10.1007/s11307-012-0558-y.
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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.Hum Mol Genet. 2015 Mar 1;24(5):1478-92. doi: 10.1093/hmg/ddu552. Epub 2014 Nov 6.
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Expression of HOXA10 in endometrial hyperplasia and adenocarcinoma and regulation by sex hormones in vitro.Int J Gynecol Cancer. 2011 Jul;21(5):800-5. doi: 10.1097/IGC.0b013e31821a2584.
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Serine proteases HTRA1 and HTRA3 are down-regulated with increasing grades of human endometrial cancer.Gynecol Oncol. 2006 Oct;103(1):253-60. doi: 10.1016/j.ygyno.2006.03.006. Epub 2006 May 2.
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Loss of Hugl-1 expression associates with lymph node metastasis in endometrial cancer.Oncol Res. 2007;16(9):431-5. doi: 10.3727/000000007783980855.
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Matrix metalloproteinase-26 (matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer.Gynecol Oncol. 2004 Sep;94(3):661-70. doi: 10.1016/j.ygyno.2004.05.024.
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Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts. Ulster Med J. 2008 Jan;77(1):25-30.
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Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F. Mol Cancer Res. 2011 Nov;9(11):1479-92. doi: 10.1158/1541-7786.MCR-11-0213. Epub 2011 Sep 20.
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Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation. Cell Death Dis. 2018 May 1;9(5):504. doi: 10.1038/s41419-018-0521-1.
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Plasminogen activator inhibitor type 2: potential prognostic factor for endometrial carcinomas.Neoplasma. 2001;48(6):462-7.
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LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Adv Exp Med Biol. 2017;943:211-241. doi: 10.1007/978-3-319-43139-0_7.
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Regulation of the vascular endothelial growth factor and growth by estrogen and antiestrogens through Efp in Ishikawa endometrial carcinoma cells. Oncol Rep. 2009 Feb;21(2):395-401.
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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet. 2013 Feb;45(2):136-44. doi: 10.1038/ng.2503. Epub 2012 Dec 23.
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