Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6HQDL)

Drug Name
CYANATE Drug Info
Synonyms
cyanate; ISOCYANATE; UNII-YML51WA0FW; YML51WA0FW; 661-20-1; 71000-82-3; UN2206; Cyanate ion(1-); Isocyanate ion(1-); Isocyanate ion (1-); Isocyanic acid, ion(1-); isocynate; Zyanat; Cyanat; carbonyl amide; hydrogen cyanate; UN3080; nitridooxidocarbonate(1-); AC1L2XX2; OCN(-); CHEBI:29195; CTK5I4582; CTK2H4173; BDBM26982; CNO(-1); IQPQWNKOIGAROB-UHFFFAOYSA-N; XLJMAIOERFSOGZ-UHFFFAOYSA-M; AC1Q2283; BDBM50098562; [C(N)O](-); Isocyanates, toxic, n.o.s. or isocyanate solutions, toxic, n.o.s., Fp 61 C and Bp 300 C; Isocyanates, toxic, n.o.s. o
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
105034
ChEBI ID
CHEBI:29195
CAS Number
CAS 71000-82-3
TTD Drug ID
DM6HQDL

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Carbonic anhydrase I (CA-I)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [5]
Ethoxzolamide DMVO4ED Glaucoma/ocular hypertension 9C61 Approved [6]
Dichlorphenamide DMH7IDQ Chronic glaucoma 9C61.0Z Approved [6]
Methazolamide DM7J2TA Glaucoma/ocular hypertension 9C61 Approved [7]
Acetazolamide DM1AF5U Absence epilepsy Approved [6]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [8]
PARABEN DMEW5Z8 N. A. N. A. Phase 3 [9]
CG-100649 DMIKMA9 Arthritis FA20 Phase 3 [10]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [8]
Coumate DMVKW0N Breast cancer 2C60-2C65 Phase 2 [11]
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Drug(s) Affected By Glutathione reductase, mitochondrial (GSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [12]
Ketoprofen DMRKXPT Bursitis Approved [13]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [15]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [17]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [18]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [19]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [21]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [22]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [23]
Fructose DM43AN2 Vomiting MD90 Approved [13]
Ketoprofen DMRKXPT Bursitis Approved [13]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [24]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [25]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [26]
Gefitinib DM15F0X Colon adenocarcinoma Approved [27]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [28]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [29]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [30]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [31]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [32]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [38]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [39]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [40]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [41]
Gefitinib DM15F0X Colon adenocarcinoma Approved [42]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [43]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [44]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [43]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [45]
Selenium DM25CGV N. A. N. A. Approved [46]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [47]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [48]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [49]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [50]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [51]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [52]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [53]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [41]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [29]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [45]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [49]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [55]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [56]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [57]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [52]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [58]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [41]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [43]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [44]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [59]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [43]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [63]
Etretinate DM2CZFA Keratosis ED56 Approved [64]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [66]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [67]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
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Drug(s) Affected By Interleukin-12 subunit alpha (IL12A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [71]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [74]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [76]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [77]
Arsenic DMTL2Y1 N. A. N. A. Approved [78]
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Drug(s) Affected By Interleukin-12 subunit beta (IL12B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [31]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [71]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [79]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Capsaicin DMGMF6V Back pain ME84.Z Approved [81]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [82]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [83]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [84]
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Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [85]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [86]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Etretinate DM2CZFA Keratosis ED56 Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [91]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [20]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [95]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [96]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [97]
Paclitaxel DMLB81S Breast carcinoma Approved [98]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [99]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [100]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [101]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [102]
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Drug(s) Affected By Serine/threonine-protein kinase ATR (ATR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [103]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [20]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [105]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [106]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [108]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [20]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [109]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [110]
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Drug(s) Affected By Catenin alpha-3 (CTNNA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [112]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [113]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [114]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [115]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [116]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [117]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carbonic anhydrase I (CA-I) TTHQPL7 CAH1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Catenin alpha-3 (CTNNA3) OT9Z0P1E CTNA3_HUMAN Drug Response [2]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [3]
Glutathione reductase, mitochondrial (GSR) OTM2TUYM GSHR_HUMAN Gene/Protein Processing [4]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Post-Translational Modifications [4]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Gene/Protein Processing [4]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [4]
Interleukin-12 subunit alpha (IL12A) OTDQT8GI IL12A_HUMAN Gene/Protein Processing [4]
Interleukin-12 subunit beta (IL12B) OT0JF8A3 IL12B_HUMAN Gene/Protein Processing [4]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Gene/Protein Processing [4]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [4]

References

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3 Inflammatory response to isocyanates and onset of genomic instability in cultured human lung fibroblasts. Genet Mol Res. 2009 Feb 10;8(1):129-43. doi: 10.4238/vol8-1gmr544.
4 Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes. J Biochem Mol Toxicol. 2008 Nov-Dec;22(6):429-40.
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14 Cytotoxic Effects of Cannabinoids on Human HT-29 Colorectal Adenocarcinoma Cells: Different Mechanisms of THC, CBD, and CB83. Int J Mol Sci. 2020 Aug 1;21(15):5533. doi: 10.3390/ijms21155533.
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16 Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. Food Chem Toxicol. 2021 Dec;158:112664. doi: 10.1016/j.fct.2021.112664. Epub 2021 Nov 9.
17 Quercetin modulates Nrf2 and glutathione-related defenses in HepG2 cells: Involvement of p38. Chem Biol Interact. 2012 Jan 25;195(2):154-64.
18 Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. Toxicol In Vitro. 2017 Mar;39:93-103.
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20 Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines. Cancer Res. 2005 Dec 15;65(24):11676-88.
21 An approach to elucidate potential mechanism of renal toxicity of arsenic trioxide. Exp Hematol. 2007 Feb;35(2):252-62.
22 Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells. J Biochem Mol Toxicol. 2020 Feb;34(2):e22433. doi: 10.1002/jbt.22433. Epub 2020 Jan 9.
23 A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations. Toxicol Appl Pharmacol. 2017 Nov 1;334:18-23. doi: 10.1016/j.taap.2017.08.017. Epub 2017 Sep 1.
24 CBD Promotes Oral Ulcer Healing via Inhibiting CMPK2-Mediated Inflammasome. J Dent Res. 2022 Feb;101(2):206-215. doi: 10.1177/00220345211024528. Epub 2021 Jul 16.
25 Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway. Toxicol Sci. 2014 Feb;137(2):404-15. doi: 10.1093/toxsci/kft254. Epub 2013 Nov 5.
26 Anti-inflammatory effects of the GABA(B) receptor agonist baclofen in allergic contact dermatitis. Exp Dermatol. 2010 Jul 1;19(7):661-6. doi: 10.1111/j.1600-0625.2010.01076.x. Epub 2010 Feb 25.
27 Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways. World J Gastrointest Oncol. 2022 Feb 15;14(2):450-477. doi: 10.4251/wjgo.v14.i2.450.
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29 Oxidative Stress Alters miRNA and Gene Expression Profiles in Villous First Trimester Trophoblasts. Biomed Res Int. 2015;2015:257090. doi: 10.1155/2015/257090. Epub 2015 Aug 3.
30 Differential expression of microRNAs and their predicted targets in renal cells exposed to amphotericin B and its complex with copper (II) ions. Toxicol Mech Methods. 2017 Sep;27(7):537-543. doi: 10.1080/15376516.2017.1333554. Epub 2017 Jun 8.
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34 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
35 Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. J Immunol. 2008 May 15;180(10):6988-96. doi: 10.4049/jimmunol.180.10.6988.
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39 Detection of Drug-Responsive T-Lymphocytes in a Case of Fatal Antituberculosis Drug-Related Liver Injury. Chem Res Toxicol. 2016 Nov 21;29(11):1793-1795. doi: 10.1021/acs.chemrestox.6b00393. Epub 2016 Nov 9.
40 Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells. Front Physiol. 2016 Nov 24;7:559. doi: 10.3389/fphys.2016.00559. eCollection 2016.
41 ERE-independent ERalpha target genes differentially expressed in human breast tumors. Mol Cell Endocrinol. 2005 Dec 21;245(1-2):53-9. doi: 10.1016/j.mce.2005.10.003. Epub 2005 Nov 17.
42 Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction. J Toxicol Sci. 2020;45(11):673-680. doi: 10.2131/jts.45.673.
43 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
44 Gypenosides protect retinal pigment epithelium cells from oxidative stress. Food Chem Toxicol. 2018 Feb;112:76-85.
45 (9)-Tetrahydrocannabinol Suppresses Monocyte-Mediated Astrocyte Production of Monocyte Chemoattractant Protein 1 and Interleukin-6 in a Toll-Like Receptor 7-Stimulated Human Coculture. J Pharmacol Exp Ther. 2019 Oct;371(1):191-201. doi: 10.1124/jpet.119.260661. Epub 2019 Aug 5.
46 Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions. Toxicol Lett. 2007 Mar 8;169(2):162-76. doi: 10.1016/j.toxlet.2007.01.006. Epub 2007 Jan 19.
47 Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. Arch Toxicol. 2018 Jun;92(6):2043-2054. doi: 10.1007/s00204-018-2199-7. Epub 2018 Mar 29.
48 Spironolactone induces apoptosis in human mononuclear cells. Association between apoptosis and cytokine suppression. Apoptosis. 2006 Apr;11(4):573-9. doi: 10.1007/s10495-006-4919-3.
49 Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis Res Ther. 2009;11(1):R15.
50 Mechanisms of dexamethasone-induced disturbed sleep and fatigue in paediatric patients receiving treatment for ALL. Eur J Cancer. 2010 Jul;46(10):1848-55. doi: 10.1016/j.ejca.2010.03.026. Epub 2010 Apr 17.
51 Cannabidiol enhances cytotoxicity of anti-cancer drugs in human head and neck squamous cell carcinoma. Sci Rep. 2020 Nov 26;10(1):20622. doi: 10.1038/s41598-020-77674-y.
52 Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. Exp Dermatol. 2009 Nov;18(11):969-78. doi: 10.1111/j.1600-0625.2009.00884.x. Epub 2009 Apr 8.
53 Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages. Antivir Ther. 2007;12(4):489-500.
54 Blood cell oxidative stress precedes hemolysis in whole blood-liver slice co-cultures of rat, dog, and human tissues. Toxicol Appl Pharmacol. 2010 May 1;244(3):354-65. doi: 10.1016/j.taap.2010.01.017. Epub 2010 Feb 6.
55 Monomeric and oligomeric flavanols maintain the endogenous glucocorticoid response in human macrophages in pro-oxidant conditions in vitro. Chem Biol Interact. 2018 Aug 1;291:237-244.
56 Nicotine up-regulates IL-8 expression in human gingival epithelial cells following stimulation with IL-1 or P. gingivalis lipopolysaccharide via nicotinic acetylcholine receptor signalling. Arch Oral Biol. 2012 May;57(5):483-90. doi: 10.1016/j.archoralbio.2011.10.007. Epub 2011 Nov 25.
57 Ca(2+) Signaling and IL-8 Secretion in Human Testicular Peritubular Cells Involve the Cation Channel TRPV2. Int J Mol Sci. 2018 Sep 19;19(9):2829. doi: 10.3390/ijms19092829.
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