Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM2POTE)

• Drug Name: Colchicine Drug Info
• Synonyms: Colchicin; Colchicina; Colchicinum; Colchineos; Colchisol; Colchysat; Colcin; Colcrys; Colsaloid; Colstat; Condylon; Goutnil; Kolkicin; LOC; Binds to tubulin; Colchicin [German]; Colchicina [Italian]; Colchicine [JAN]; Inhibits microtubular assembly; Spindle poison; C 9754; Colchicine (TN); Colchicine, Colchicum autumnale; MPC-004; N-Acetyl trimethylcolchicinic acid methylether; Colchicine (JP15/USP); Colchicine, (R)-Isomer; Benzo(a)heptalen-9(5H)-one; Colchicine, (+-)-Isomer; N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide; N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide; N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide; N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[.alpha.]heptalen-7-yl)-acetamide; N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-acetamide; (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; 7-alpha-H-Colchicine; 7.alpha.H-Colchicine; 7alphaH-Colchicine

Indication

Disease Entry	ICD 11	Status	REF
Acute gout flare	FA25.0	Approved	[1]
Acute gouty arthritis	FA25.0	Approved	[2]
Gout	FA25	Approved	[3]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 2	[4]
Familial Mediterranean fever		Investigative	[3]

• Therapeutic Class: Gout Suppressants
• Cross-matching ID:
  PubChem CID: 6167
  ChEBI ID: CHEMBL107
  CAS Number: CAS 64-86-8
  TTD Drug ID: DM2POTE
  VARIDT Drug ID: DR00135
  INTEDE Drug ID: DR0372
  ACDINA Drug ID: D00149

Molecule-Related Drug Atlas

Drug(s) Targeting Tubulin (TUB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[15]
Vinorelbine	DMVXFYE	Advanced cancer	2A00-2F9Z	Approved	[16]
Cabazitaxel	DMPAZHC	Breast cancer	2C60-2C65	Approved	[17]
Ixabepilone	DM2OZ3G	Breast cancer	2C60-2C65	Approved	[17]
Eribulin	DM1DX4Q	Breast cancer	2C60-2C65	Approved	[17]
Epothilon	DMITJRU	Ovarian cancer	2C73	Phase 3	[18]
DOLASTATIN-10	DMDUV1S	Solid tumour/cancer	2A00-2F9Z	Phase 2	[19]
BMS-188797	DML1CK2	Solid tumour/cancer	2A00-2F9Z	Phase 2	[20]
Indibulin	DM6OFJ8	Advanced sarcoma	2A60-2C35	Phase 2	[21]
Soblidotin	DMO4EYX	Solid tumour/cancer	2A00-2F9Z	Phase 2	[22]

Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[23]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[24]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[25]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[26]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[27]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[28]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[29]
Glutathione	DMAHMT9	Human immunodeficiency virus infection	1C62	Approved	[30]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[31]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[32]

Drug(s) Transported By P-glycoprotein 1 (ABCB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Amoxicillin	DMUYNEI	Acute otitis media	AB00	Approved	[28]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[33]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[34]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[35]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[34]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[34]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[36]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[34]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[37]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[38]

Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[39]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[40]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[41]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[42]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[43]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[44]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[45]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[46]
Prasterone	DM67VKL	Chronic obstructive pulmonary disease	CA22	Approved	[40]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[47]

Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Flupentixol	DM0DJ9O	Schizophrenia	6A20	Approved	[48]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[49]
Crizotinib	DM4F29C	Non-small-cell lung cancer	2C25.Y	Approved	[50]
Lamotrigine	DM8SXYG	Bipolar disorder	6A60	Approved	[51]
Cepharanthine	DM9Y5JB	N. A.	N. A.	Approved	[52]
Itraconazole	DMCR1MV	Aspergillosis	1F20	Approved	[53]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[54]
Midostaurin	DMI6E0R	Acute myeloid leukaemia	2A60	Approved	[55]
Trifluoperazine	DMKBYWI	Anxiety		Approved	[56]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[54]

Drug(s) Affected By Succinate dehydrogenase assembly factor 1, mitochondrial (SDHAF1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[59]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[60]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[61]
Formaldehyde	DM7Q6M0	Discovery agent	N.A.	Investigative	[62]

Drug(s) Affected By E3 ubiquitin-protein ligase TRIM38 (TRIM38)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[65]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[68]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[69]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[70]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]

Drug(s) Affected By Ectoderm-neural cortex protein 1 (ENC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[72]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[73]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Nefazodone	DM4ZS8M	Major depressive disorder	6A70.3	Approved	[74]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[75]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mifepristone	DMGZQEF	Cushing disease	5A70	Approved	[76]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]

Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[78]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[79]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[80]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[81]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[83]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[84]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[83]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[85]

Drug(s) Affected By Plexin-B2 (PLXNB2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[87]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[90]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]

Drug(s) Affected By E3 ubiquitin-protein ligase RNF113A (RNF113A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[92]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]

Drug(s) Affected By DNA repair protein RAD51 homolog 3 (RAD51C)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[95]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[97]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[97]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]

Drug(s) Affected By TP53-regulated inhibitor of apoptosis 1 (TRIAP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[102]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[103]
Adefovir Dipivoxil	DMMAWY1	Hepatitis B virus infection	1E51.0	Approved	[102]

Drug(s) Affected By Dual specificity protein phosphatase 14 (DUSP14)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[104]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[81]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[105]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[69]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]

Drug(s) Affected By Kinesin-like protein KIF20A (KIF20A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[106]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[108]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]

Drug(s) Affected By CUGBP Elav-like family member 2 (CELF2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[109]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[110]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[111]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[61]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[112]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]

Drug(s) Affected By Prothrombin (F2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[113]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[114]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[115]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[116]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[117]
Phytonadione	DM8HDOL	Bleeding disorder	GA20-GA21	Approved	[118]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[119]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[120]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[121]

Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[122]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[123]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[124]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[125]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[126]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[127]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[128]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[129]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[73]

Drug(s) Affected By Transcription factor Jun (JUN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mitoxantrone	DMM39BF	Acute myelogenous leukaemia	2A41	Approved	[130]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[131]
Fructose	DM43AN2	Vomiting	MD90	Approved	[122]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[132]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[133]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[104]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[134]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[135]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[136]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[137]

Drug(s) Affected By Keratin, type I cytoskeletal 18 (KRT18)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[138]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[109]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[139]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[140]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Nevirapine	DM6HX9B	Human immunodeficiency virus infection	1C62	Approved	[141]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[142]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[143]

Drug(s) Affected By Poly polymerase 1 (PARP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[144]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[145]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[146]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[147]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[148]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[149]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[148]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[150]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[151]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[152]

Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[153]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[154]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[155]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[156]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[133]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[157]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[158]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[159]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[160]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[158]

Drug(s) Affected By Microtubule-associated protein 2 (MAP2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[161]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[84]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[162]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[163]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Enzalutamide	DMGL19D	Prostate cancer	2C82.0	Approved	[164]

Drug(s) Affected By Cadherin-1 (CDH1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[138]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[166]
Liraglutide	DM3FXPS	Non-insulin dependent diabetes	5A11	Approved	[167]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[168]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[169]
Polyethylene glycol	DM4I1JP	Constipation	DD91.1	Approved	[170]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[171]

Drug(s) Affected By CD59 glycoprotein (CD59)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[79]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[172]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[14]

Drug(s) Affected By Tyrosine aminotransferase (TAT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[173]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[174]
Bosentan	DMIOGBU	Pulmonary arterial hypertension	BB01.0	Approved	[175]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[176]
Miconazole	DMPMYE8	Cutaneous candidiasis	1F23.14	Approved	[177]
Azacitidine	DMTA5OE	Acute myelogenous leukaemia	2A41	Approved	[178]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[179]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[71]

Drug(s) Affected By NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[180]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[182]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[182]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[183]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[180]

Drug(s) Affected By Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[73]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[184]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[110]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[185]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[65]

Drug(s) Affected By M-phase inducer phosphatase 1 (CDC25A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[186]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[187]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[188]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[189]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[190]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[191]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[192]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[193]

Drug(s) Affected By Sodium-dependent serotonin transporter (SLC6A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[194]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[195]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[196]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[197]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Aripiprazole	DM3NUMH	Bipolar I disorder		Approved	[198]
Gabapentin	DM6T924	Complex partial seizure	8A68.0	Approved	[199]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Mepyramine	DMB4SFH	Allergic rhinitis	CA08.0	Approved	[200]

Drug(s) Affected By Replication factor C subunit 1 (RFC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[92]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[201]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[202]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]

Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[203]
Triacetin	DM0AEPG	Onychomycosis	EE12.1	Approved	[204]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[104]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[80]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[205]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[180]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[206]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[108]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[207]

Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[208]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[209]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[134]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[210]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[211]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[180]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[212]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[213]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[149]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[214]

Drug(s) Affected By Tumor necrosis factor ligand superfamily member 9 (TNFSF9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[113]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[215]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[215]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[216]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]

Drug(s) Affected By RNA-binding protein 34 (RBM34)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[121]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Cytarabine	DMZD5QR	Acute lymphoblastic leukaemia	2A85	Approved	[217]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[60]

Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[218]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[132]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[219]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[220]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[221]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[222]
Glucosamine	DM4ZLFD	Osteoarthritis	FA00-FA05	Approved	[223]
Vinblastine	DM5TVS3	Advanced cancer	2A00-2F9Z	Approved	[224]
Ethacrynic acid	DM60QMR	Edema	MG29	Approved	[225]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[226]

Drug(s) Affected By Mitogen-activated protein kinase 9 (MAPK9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[132]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[187]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[227]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[228]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Vinblastine	DM5TVS3	Advanced cancer	2A00-2F9Z	Approved	[224]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[229]
Sorbitol	DMAN0DE	Constipation	DD91.1	Approved	[230]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]

Drug(s) Affected By LIM/homeobox protein Lhx2 (LHX2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[231]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]

Drug(s) Affected By DNA mismatch repair protein Msh6 (MSH6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[186]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[232]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]

Drug(s) Affected By RecQ-like DNA helicase BLM (BLM)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[186]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]

Drug(s) Affected By Ataxin-1 (ATXN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[109]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[135]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[84]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[233]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[102]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[102]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]

Drug(s) Affected By Ras-related protein Rap-2b (RAP2B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[84]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[59]

Drug(s) Affected By Protein BTG1 (BTG1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[234]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[235]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[236]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[237]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[234]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[65]

Drug(s) Affected By Protein BTG2 (BTG2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[180]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[232]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[238]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[239]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[116]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[173]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[240]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[237]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]

Drug(s) Affected By Transcription factor E2F1 (E2F1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[241]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[144]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[242]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[243]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[244]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[245]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[246]

Drug(s) Affected By Myelin transcription factor 1 (MYT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[247]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[248]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[249]
Permethrin	DMZ0Q1G	Pediculus capitis infestation	1G00.0	Approved	[250]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[251]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[247]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[248]
Octanal	DMTN0OK	N. A.	N. A.	Investigative	[252]

Drug(s) Affected By DNA-binding protein inhibitor ID-3 (ID3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[156]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[253]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[254]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[113]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[255]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[256]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[253]

Drug(s) Affected By Tripartite motif-containing protein 26 (TRIM26)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[173]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[257]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[107]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[258]

Drug(s) Affected By E3 ubiquitin-protein ligase TRIM32 (TRIM32)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[258]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[59]

Drug(s) Affected By Chromatin assembly factor 1 subunit A (CHAF1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[92]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[259]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]

Drug(s) Affected By Chromatin assembly factor 1 subunit B (CHAF1B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[258]

Drug(s) Affected By DNA topoisomerase 3-alpha (TOP3A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[69]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[201]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[60]
Torcetrapib	DMDHYM7	Hyperlipidaemia	5C80	Discontinued in Phase 2	[260]
Lithium chloride	DMHYLQ2	Discovery agent	N.A.	Investigative	[261]

Drug(s) Affected By Oligodendrocyte transcription factor 2 (OLIG2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[262]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[199]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[231]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[231]
Sulfadiazine	DMTW3R8	Rheumatic fever	1B40-1B42	Approved	[199]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[199]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[249]
Carbamazepine	DMZOLBI	Epilepsy	8A60-8A68	Approved	[121]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[60]
Glyphosate	DM0AFY7	Malaria	1F40-1F45	Investigative	[199]

Drug(s) Affected By Protein BTG3 (BTG3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[116]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[263]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[264]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[112]

Drug(s) Affected By Protein-tyrosine kinase 2-beta (PTK2B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[232]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[265]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[266]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[259]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[267]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[258]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[59]
Tamibarotene	DM3G74J	T-cell leukaemia	2A90	Phase 3	[232]

Drug(s) Affected By Histone RNA hairpin-binding protein (SLBP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[109]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[161]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[69]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[268]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]

Drug(s) Affected By Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Vinblastine	DM5TVS3	Advanced cancer	2A00-2F9Z	Approved	[269]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[270]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[271]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[249]
Phenylephrine	DMZHUO5	Allergic rhinitis	CA08.0	Approved	[272]
SNDX-275	DMH7W9X	Breast cancer	2C60-2C65	Phase 3	[67]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[251]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[273]

Drug(s) Affected By Neutral amino acid transporter B(0) (SLC1A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[102]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[102]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[274]

Drug(s) Affected By E3 ubiquitin-protein ligase RNF19B (RNF19B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[256]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[256]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Motexafin gadolinium	DMEJKRF	Brain cancer	2A00	Approved	[275]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[256]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]

Drug(s) Affected By Protein MCM10 homolog (MCM10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[186]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[276]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[193]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[121]
Palbociclib	DMD7L94	Breast cancer	2C60-2C65	Approved	[277]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]

Drug(s) Affected By Partner and localizer of BRCA2 (PALB2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[121]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[278]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]

Drug(s) Affected By E3 ubiquitin-protein ligase TRIM22 (TRIM22)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[279]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[280]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[281]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[274]

Drug(s) Affected By Leucine-rich repeat-containing protein 47 (LRRC47)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[282]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[63]

Drug(s) Affected By Protein tyrosine phosphatase type IVA 1 (PTP4A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[283]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[70]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[61]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[284]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[285]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]

Drug(s) Affected By Cytochrome c oxidase assembly factor 7 (COA7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[286]

Drug(s) Affected By Mitochondrial potassium channel (CCDC51)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[286]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[71]

Drug(s) Affected By Integrator complex subunit 15 (INTS15)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[59]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[63]

Drug(s) Affected By Pleckstrin homology domain-containing family F member 1 (PLEKHF1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[287]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[288]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[289]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[290]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[60]

Drug(s) Affected By Krueppel-like factor 6 (KLF6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[144]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[291]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[245]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[67]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]

Drug(s) Affected By Cell division control protein 6 homolog (CDC6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[186]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[245]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[292]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[232]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[190]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]

Drug(s) Affected By Protein orai-3 (ORAI3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[102]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[102]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[259]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]

Drug(s) Affected By Protein pelota homolog (PELO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[293]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[294]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]

Drug(s) Affected By TIMELESS-interacting protein (TIPIN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[295]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[296]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]

Drug(s) Affected By tRNA pseudouridine(38/39) synthase (PUS3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]

Drug(s) Affected By Transmembrane protein 185B (TMEM185B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[258]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[297]

Drug(s) Affected By Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Indomethacin	DMSC4A7	Bursitis		Approved	[298]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[107]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[297]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Adenine	DMZLHKJ	Malnutrition	5B50-5B71	Approved	[9]

Drug(s) Affected By GrpE protein homolog 1, mitochondrial (GRPEL1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[299]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[110]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[86]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]

Drug(s) Affected By p53-induced death domain-containing protein 1 (PIDD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[300]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[301]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Adefovir Dipivoxil	DMMAWY1	Hepatitis B virus infection	1E51.0	Approved	[102]

Drug(s) Affected By Fructose-2,6-bisphosphatase TIGAR (TIGAR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[300]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[69]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[102]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[201]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]

Drug(s) Affected By DNA damage-inducible transcript 4 protein (DDIT4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[203]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[302]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[303]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[304]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[305]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[75]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[240]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]

Drug(s) Affected By Homologous-pairing protein 2 homolog (PSMC3IP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[306]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[121]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[259]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[296]

Drug(s) Affected By Protein CLN8 (CLN8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[109]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[113]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[307]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[88]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[89]

Drug(s) Affected By rRNA methyltransferase 2, mitochondrial (MRM2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[259]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]

Drug(s) Affected By Frizzled-1 (FZD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[93]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[173]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[70]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[100]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[9]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[308]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]

Drug(s) Affected By SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[107]
Selenium	DM25CGV	N. A.	N. A.	Approved	[63]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[199]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Gabapentin	DM6T924	Complex partial seizure	8A68.0	Approved	[199]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Melphalan	DMOLNHF	Hematologic disease	3C0Z	Approved	[309]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[310]

Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-1 (PRKAB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[102]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[311]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[101]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[312]

Drug(s) Affected By Pleckstrin homology-like domain family A member 3 (PHLDA3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[94]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[71]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[102]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[181]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[102]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]

Drug(s) Affected By Sestrin-1 (SESN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[159]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[64]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[75]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[240]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[313]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[98]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[98]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[57]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[102]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[99]

Drug(s) Affected By ATP-binding cassette sub-family A member 13 (ABCA13)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[58]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[77]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[310]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[314]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[92]
Trichostatin A	DM9C8NX	Solid tumour/cancer	2A00-2F9Z	Investigative	[315]
KOJIC ACID	DMP84CS	Discovery agent	N.A.	Investigative	[316]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Tubulin (TUB)	TTML2WA	NOUNIPROTAC	Binder	[5]

Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[6]
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[7]

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 3A4 (CYP3A4) Main DME	DE4LYSA	CP3A4_HUMAN	Substrate	[8]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
5'-AMP-activated protein kinase subunit beta-1 (PRKAB1)	OT1OG4QZ	AAKB1_HUMAN	Gene/Protein Processing	[9]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Gene/Protein Processing	[10]
Ataxin-1 (ATXN1)	OTQF0HNR	ATX1_HUMAN	Gene/Protein Processing	[9]
ATP-binding cassette sub-family A member 13 (ABCA13)	OTTHTUQN	ABCAD_HUMAN	Drug Response	[11]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Gene/Protein Processing	[12]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Gene/Protein Processing	[13]
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2)	OTIN6G20	CPT2_HUMAN	Gene/Protein Processing	[9]
CD59 glycoprotein (CD59)	OTSUMQDH	CD59_HUMAN	Gene/Protein Processing	[14]
Cell division control protein 6 homolog (CDC6)	OTX93FE7	CDC6_HUMAN	Gene/Protein Processing	[9]
Chromatin assembly factor 1 subunit A (CHAF1A)	OTXSSY4H	CAF1A_HUMAN	Gene/Protein Processing	[9]

References

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