Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBSK7X)

Drug Name
Isoflurophate Drug Info
Synonyms
DFP; DIFP; Diflupyl; Diflurophate; Diisopropylfluorfosfat; Diisopropylfluorophosphate; Diisopropylfluorphosphorsaeureester; Diisopropylphosphofluoridate; Diisopropylphosphorofluoridate; Dyflos; Floropryl; Fluoropryl; Fluorostigmine; Fluostigmine; Fluropryl; Isofluorophate; Isofluorphate; Isoflurophosphate; Neoglaucit; Di isopropylphosphorofluoridate; Diisopropoxyphosphoryl fluoride; Diisopropyl fluoridophosphate; Diisopropyl fluorophosphate; Diisopropyl fluorophosphonate; Diisopropyl phosphofluoridate; Diisopropyl phosphorofluoridate; Diisopropylfluorfosfat [Czech]; Diisopropylfluorophosphoric acid ester; Diisopropylfluorphosphorsaeureester [German]; Disiopropyl fluorophosphonate; Fluorodiisopropyl phosphate; Isoflurophate [USP]; Isopropyl fluophosphate; Isopropyl phosphorofluoridate; Merck Brand of Isoflurophate; Phosphoric acid diisopropyl ester fluoride; EA 1152; TL 466; DIISOPROPYL-FLUOROPHOSPHATE; Di-isopropylphosphorofluoridate; Floropryl (TN); Fluophosphoric acid, diisopropyl ester; Fluorophosphoric acid, diisopropyl ester; Isoflurophate (USP); PF-3; Phosphorofluoridic acid, diisopropyl ester; T-1703; Bis(1-methylethyl) Phosphorofluoridate; Dipropan-2-yl phosphorofluoridoate; O,O-Diisopropyl fluorophosphate; Bis(propan-2-yl) fluorophosphate; O,O'-Diisopropyl phosphoryl fluoride; Phosphorofluoridic acid, bis(1-methylethyl) ester; 2-[fluoro(propan-2-yloxy)phosphoryl]oxypropane
Indication
Disease Entry ICD 11 Status REF
Glaucoma/ocular hypertension 9C61 Approved [1]
Therapeutic Class
Antiglaucomic Agents
Cross-matching ID
PubChem CID
5936
ChEBI ID
CHEBI:17941
CAS Number
CAS 55-91-4
TTD Drug ID
DMBSK7X

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Acetylcholinesterase (AChE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [10]
Donepezil DMIYG7Z Advanced cancer 2A00-2F9Z Approved [11]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [12]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [13]
Huperzine A DMMAWLU Alzheimer disease 8A20 Approved [14]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [15]
YM443 DMNZCI1 Functional dyspepsia DD90.3 Approved [16]
Ambenonium DMOP0BL Myasthenia gravis 8C6Y Approved [17]
Demecarium bromide DMAYEU1 Open-angle glaucoma 9C61 Approved [18]
Pyridostigmine DM8HO1L Myasthenia gravis 8C6Y Approved [19]
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Drug(s) Affected By Cholinesterase (BCHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [20]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [21]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [22]
Rivastigmine DMG629M Alzheimer disease 8A20 Approved [23]
Donepezil DMIYG7Z Advanced cancer 2A00-2F9Z Approved [24]
Succinylcholine DM2ET1M Plasma cell myeloma 2A83.1 Approved [25]
Ethopropazine DM0N3L7 Parkinson disease 8A00.0 Approved [21]
Dimenhydrinate DM264B3 Meniere disease AB31.0 Approved [26]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [27]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [26]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [28]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [24]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [29]
Diazepam DM08E9O Alcohol withdrawal Approved [30]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [31]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [32]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [33]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
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Drug(s) Affected By Serotransferrin (TF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [39]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [41]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [42]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [43]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [44]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [45]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [46]
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Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [47]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Selenium DM25CGV N. A. N. A. Approved [49]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [55]
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Drug(s) Affected By Histidine decarboxylase (HDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [57]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [58]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [59]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [60]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [61]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [62]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [63]
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Drug(s) Affected By Aromatic-L-amino-acid decarboxylase (DDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [67]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [68]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [69]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [38]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [70]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [71]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [72]
Methotrexate DM2TEOL Anterior urethra cancer Approved [73]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [72]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [75]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [76]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [77]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
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Drug(s) Affected By Glutamate decarboxylase 2 (GAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Arsenic DMTL2Y1 N. A. N. A. Approved [80]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [41]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [63]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [5]
Chlorphrifos oxon DMGBT68 Discovery agent N.A. Investigative [5]
CHLORPYRIFOS DMKPUI6 Discovery agent N.A. Investigative [5]
PARAOXON DMN4ZKC Discovery agent N.A. Investigative [5]
Hexadecanoic acid DMWUXDZ Discovery agent N.A. Investigative [81]
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Drug(s) Affected By Patatin-like phospholipase domain-containing protein 6 (PNPLA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [82]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [83]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [60]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [84]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [85]
Arsenic DMTL2Y1 N. A. N. A. Approved [80]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [86]
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Drug(s) Affected By Glutamate decarboxylase 1 (GAD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [87]
Panobinostat DM58WKG Chronic graft versus host disease Approved [61]
Leflunomide DMR8ONJ Arthritis FA20 Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Clozapine DMFC71L Schizophrenia 6A20 Approved [91]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [92]
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Drug(s) Affected By Xaa-Pro dipeptidase (PEPD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [94]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [95]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [96]
Gentamicin DMKINJO Bacteremia 1A73 Approved [97]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [38]
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Drug(s) Affected By Serum paraoxonase/arylesterase 1 (PON1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [101]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [102]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Panobinostat DM58WKG Chronic graft versus host disease Approved [61]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [105]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [106]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [99]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetylcholinesterase (AChE) TT1RS9F ACES_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Gene/Protein Processing [3]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [4]
Aromatic-L-amino-acid decarboxylase (DDC) OT0TSW09 DDC_HUMAN Protein Interaction/Cellular Processes [5]
Cholinesterase (BCHE) OTOH3WQ9 CHLE_HUMAN Gene/Protein Processing [6]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Protein Interaction/Cellular Processes [7]
Glutamate decarboxylase 1 (GAD1) OT52Z39J DCE1_HUMAN Protein Interaction/Cellular Processes [5]
Glutamate decarboxylase 2 (GAD2) OTW1GLEM DCE2_HUMAN Protein Interaction/Cellular Processes [5]
Histidine decarboxylase (HDC) OT4WA5YQ DCHS_HUMAN Protein Interaction/Cellular Processes [5]
Patatin-like phospholipase domain-containing protein 6 (PNPLA6) OTT5T45Q PLPL6_HUMAN Gene/Protein Processing [8]
Serotransferrin (TF) OT41PEMS TRFE_HUMAN Protein Interaction/Cellular Processes [9]

References

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