DDI Drug Name |
DDI Drug ID |
Severity |
Mechanism |
Comorbidity |
REF |
Oliceridine |
DM6MDCF
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Oliceridine. |
Acute pain [MG31]
|
[12] |
Budesonide |
DMJIBAW
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Budesonide. |
Asthma [CA23]
|
[13] |
Desipramine |
DMT2FDC
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Desipramine. |
Attention deficit hyperactivity disorder [6A05]
|
[14] |
Lamotrigine |
DM8SXYG
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Lamotrigine. |
Bipolar disorder [6A60]
|
[14] |
Loperamide |
DMOJZQ9
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Loperamide. |
Bowel habit change [ME05]
|
[12] |
Phenylbutazone |
DMAYL0T
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Phenylbutazone. |
Chronic pain [MG30]
|
[15] |
Dihydrocodeine |
DMB0FWL
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Dihydrocodeine. |
Chronic pain [MG30]
|
[16] |
Ketoprofen |
DMRKXPT
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Ketoprofen. |
Chronic pain [MG30]
|
[14] |
Morphine |
DMRMS0L
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Morphine. |
Chronic pain [MG30]
|
[12] |
Levomilnacipran |
DMV26S8
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Levomilnacipran. |
Chronic pain [MG30]
|
[14] |
Alfentanil |
DMVO0UB
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Alfentanil. |
Corneal disease [9A76-9A78]
|
[12] |
Remifentanil |
DMZTXCH
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Remifentanil. |
Corneal disease [9A76-9A78]
|
[12] |
Methadone |
DMTW6IU
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Methadone. |
Cough [MD12]
|
[12] |
Sertraline |
DM0FB1J
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Sertraline. |
Depression [6A70-6A7Z]
|
[14] |
Trimipramine |
DM1SC8M
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Trimipramine. |
Depression [6A70-6A7Z]
|
[14] |
Imipramine |
DM2NUH3
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Imipramine. |
Depression [6A70-6A7Z]
|
[14] |
Fluoxetine |
DM3PD2C
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Fluoxetine. |
Depression [6A70-6A7Z]
|
[14] |
Nortriptyline |
DM4KDYJ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Nortriptyline. |
Depression [6A70-6A7Z]
|
[14] |
Vilazodone |
DM4LECQ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Vilazodone. |
Depression [6A70-6A7Z]
|
[14] |
Paroxetine |
DM5PVQE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Paroxetine. |
Depression [6A70-6A7Z]
|
[14] |
Vortioxetine |
DM6F1PU
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Vortioxetine. |
Depression [6A70-6A7Z]
|
[14] |
Duloxetine |
DM9BI7M
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Duloxetine. |
Depression [6A70-6A7Z]
|
[14] |
Milnacipran |
DMBFE74
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Milnacipran. |
Depression [6A70-6A7Z]
|
[14] |
Escitalopram |
DMFK9HG
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Escitalopram. |
Depression [6A70-6A7Z]
|
[14] |
Desvenlafaxine |
DMHD4PE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Desvenlafaxine. |
Depression [6A70-6A7Z]
|
[14] |
Clomipramine |
DMINRKW
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Clomipramine. |
Depression [6A70-6A7Z]
|
[14] |
Amitriptyline |
DMK7F9S
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Amitriptyline. |
Depression [6A70-6A7Z]
|
[14] |
Amoxapine |
DMKITQE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Amoxapine. |
Depression [6A70-6A7Z]
|
[14] |
Mirtazapine |
DML53ZJ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Mirtazapine. |
Depression [6A70-6A7Z]
|
[14] |
Protriptyline |
DMNHTZI
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Protriptyline. |
Depression [6A70-6A7Z]
|
[14] |
Doxepin |
DMPI98T
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Doxepin. |
Depression [6A70-6A7Z]
|
[14] |
Maprotiline |
DMPWB7T
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Maprotiline. |
Depression [6A70-6A7Z]
|
[14] |
Fluvoxamine |
DMQTJSX
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Fluvoxamine. |
Depression [6A70-6A7Z]
|
[14] |
Venlafaxine |
DMR6QH0
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Venlafaxine. |
Depression [6A70-6A7Z]
|
[14] |
Citalopram derivative 1 |
DMITX1G
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Citalopram derivative 1. |
Discovery agent [N.A.]
|
[14] |
Felbamate |
DM1V5ZS
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Felbamate. |
Epilepsy/seizure [8A61-8A6Z]
|
[14] |
Oxcarbazepine |
DM5PU6O
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Oxcarbazepine. |
Epilepsy/seizure [8A61-8A6Z]
|
[14] |
Carbamazepine |
DMZOLBI
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Carbamazepine. |
Epilepsy/seizure [8A61-8A6Z]
|
[14] |
Eslicarbazepine |
DMZREFQ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Eslicarbazepine. |
Epilepsy/seizure [8A61-8A6Z]
|
[14] |
Ethacrynic acid |
DM60QMR
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Ethacrynic acid. |
Essential hypertension [BA00]
|
[17] |
Mefenamic acid |
DMK7HFI
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Mefenamic acid. |
Female pelvic pain [GA34]
|
[14] |
Furosemide |
DMMQ8ZG
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Furosemide. |
Heart failure [BD10-BD1Z]
|
[13] |
Bumetanide |
DMRV7H0
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Bumetanide. |
Heart failure [BD10-BD1Z]
|
[13] |
Torasemide |
DMXKJ6C
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Torasemide. |
Heart failure [BD10-BD1Z]
|
[17] |
Clofibrate |
DMPC1J7
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Clofibrate. |
Hyper-lipoproteinaemia [5C80]
|
[14] |
Methyldopa |
DM5I621
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Methyldopa. |
Hypertension [BA00-BA04]
|
[14] |
Enalapril |
DMNFUZR
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Enalapril. |
Hypertension [BA00-BA04]
|
[14] |
Fludrocortisone |
DMUDIR8
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Fludrocortisone. |
Hypo-osmolality/hyponatraemia [5C72]
|
[13] |
Meclofenamic acid |
DM05FXR
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Meclofenamic acid. |
Inflammatory spondyloarthritis [FA92]
|
[18] |
Vincristine |
DMINOX3
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Vincristine. |
Mature B-cell lymphoma [2A85]
|
[14] |
Deflazacort |
DMV0RNS
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Deflazacort. |
Muscular dystrophy [8C70]
|
[13] |
Urea |
DMUK75B
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Urea. |
Oesophagitis [DA24]
|
[14] |
Levomethadyl Acetate |
DM06HG5
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Levomethadyl Acetate. |
Opioid use disorder [6C43]
|
[16] |
Rofecoxib |
DM3P5DA
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Rofecoxib. |
Osteoarthritis [FA00-FA05]
|
[14] |
Valdecoxib |
DMAY7H4
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Valdecoxib. |
Osteoarthritis [FA00-FA05]
|
[14] |
Diclofenac |
DMPIHLS
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Diclofenac. |
Osteoarthritis [FA00-FA05]
|
[14] |
Naproxen |
DMZ5RGV
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Naproxen. |
Osteoarthritis [FA00-FA05]
|
[14] |
Pentazocine |
DM1XBHS
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Pentazocine. |
Pain [MG30-MG3Z]
|
[12] |
Dextropropoxyphene |
DM23HCX
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Dextropropoxyphene. |
Pain [MG30-MG3Z]
|
[16] |
Butorphanol |
DM5KYPJ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Butorphanol. |
Pain [MG30-MG3Z]
|
[12] |
Oxymorphone |
DM65AGJ
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Oxymorphone. |
Pain [MG30-MG3Z]
|
[12] |
Etodolac |
DM6WJO9
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Etodolac. |
Pain [MG30-MG3Z]
|
[14] |
Ibuprofen |
DM8VCBE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Ibuprofen. |
Pain [MG30-MG3Z]
|
[14] |
Nabumetone |
DMAT2XH
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Nabumetone. |
Pain [MG30-MG3Z]
|
[14] |
Levorphanol |
DMGS80V
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Levorphanol. |
Pain [MG30-MG3Z]
|
[12] |
Hydromorphone |
DMHP21E
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Hydromorphone. |
Pain [MG30-MG3Z]
|
[12] |
Dezocine |
DMJDB0Y
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Dezocine. |
Pain [MG30-MG3Z]
|
[12] |
Codeine |
DMJX6ZG
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Codeine. |
Pain [MG30-MG3Z]
|
[12] |
Nalbuphine |
DMOSQGU
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Nalbuphine. |
Pain [MG30-MG3Z]
|
[12] |
Buprenorphine |
DMPRI8G
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Buprenorphine. |
Pain [MG30-MG3Z]
|
[12] |
Hydrocodone |
DMQ2JO5
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Hydrocodone. |
Pain [MG30-MG3Z]
|
[12] |
Tramadol |
DMRQD04
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Tramadol. |
Pain [MG30-MG3Z]
|
[12] |
Piroxicam |
DMTK234
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Piroxicam. |
Pain [MG30-MG3Z]
|
[14] |
Meperidine |
DMX4GND
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Meperidine. |
Pain [MG30-MG3Z]
|
[12] |
Oxycodone |
DMXLKHV
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Oxycodone. |
Pain [MG30-MG3Z]
|
[12] |
Prednisone |
DM2HG4X
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Prednisone. |
Postoperative inflammation [1A00-CA43]
|
[13] |
Betamethasone |
DMAHJEF
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Betamethasone. |
Postoperative inflammation [1A00-CA43]
|
[13] |
Hydrocortisone |
DMGEMB7
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Hydrocortisone. |
Postoperative inflammation [1A00-CA43]
|
[13] |
Ketorolac |
DMI4EL5
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Ketorolac. |
Postoperative inflammation [1A00-CA43]
|
[14] |
Bromfenac |
DMKB79O
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Bromfenac. |
Postoperative inflammation [1A00-CA43]
|
[14] |
Ciclesonide |
DM2NA4K
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Ciclesonide. |
Respiratory system disease [CB40-CB7Z]
|
[13] |
Meloxicam |
DM2AR7L
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Meloxicam. |
Rheumatoid arthritis [FA20]
|
[14] |
Sulindac |
DM2QHZU
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Sulindac. |
Rheumatoid arthritis [FA20]
|
[14] |
Celecoxib |
DM6LOQU
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Celecoxib. |
Rheumatoid arthritis [FA20]
|
[14] |
Oxaprozin |
DM9UB0P
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Oxaprozin. |
Rheumatoid arthritis [FA20]
|
[14] |
Flurbiprofen |
DMGN4BY
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Flurbiprofen. |
Rheumatoid arthritis [FA20]
|
[14] |
Fenoprofen |
DML5VQ0
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Fenoprofen. |
Rheumatoid arthritis [FA20]
|
[14] |
Dexamethasone |
DMMWZET
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Dexamethasone. |
Rheumatoid arthritis [FA20]
|
[13] |
Indomethacin |
DMSC4A7
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Indomethacin. |
Rheumatoid arthritis [FA20]
|
[14] |
Tolmetin |
DMWUIJE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Tolmetin. |
Rheumatoid arthritis [FA20]
|
[14] |
Haloperidol |
DM96SE0
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Haloperidol. |
Schizophrenia [6A20]
|
[14] |
Chlorpromazine |
DMBGZI3
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Chlorpromazine. |
Schizophrenia [6A20]
|
[14] |
Fentanyl |
DM8WAHT
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Fentanyl. |
Sensation disturbance [MB40]
|
[12] |
Sufentanil |
DMU7YEL
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Sufentanil. |
Sensation disturbance [MB40]
|
[12] |
Methylprednisolone |
DM4BDON
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Methylprednisolone. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Cyclophosphamide |
DM4O2Z7
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Cyclophosphamide. |
Solid tumour/cancer [2A00-2F9Z]
|
[14] |
Vinblastine |
DM5TVS3
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Vinblastine. |
Solid tumour/cancer [2A00-2F9Z]
|
[14] |
Ifosfamide |
DMCT3I8
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Ifosfamide. |
Solid tumour/cancer [2A00-2F9Z]
|
[14] |
Prednisolone |
DMQ8FR2
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Prednisolone. |
Solid tumour/cancer [2A00-2F9Z]
|
[13] |
Cisplatin |
DMRHGI9
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Cisplatin. |
Solid tumour/cancer [2A00-2F9Z]
|
[14] |
Vinorelbine |
DMVXFYE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Vinorelbine. |
Solid tumour/cancer [2A00-2F9Z]
|
[14] |
Chlorpropamide |
DMPHZQE
|
Moderate |
Increased risk of hyponatremia by the combination of Desmopressin and Chlorpropamide. |
Type 2 diabetes mellitus [5A11]
|
[14] |
Triamcinolone |
DM98IXF
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Triamcinolone. |
Vasomotor/allergic rhinitis [CA08]
|
[13] |
Fluticasone |
DMGCSVF
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Fluticasone. |
Vasomotor/allergic rhinitis [CA08]
|
[13] |
Flunisolide |
DMZSWQC
|
Major |
Increased risk of hyponatremia by the combination of Desmopressin and Flunisolide. |
Vasomotor/allergic rhinitis [CA08]
|
[13] |
----------- |
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