General Information of Drug (ID: DMAHMT9)

Drug Name
Glutathione Drug Info
Synonyms
glutathione; 70-18-8; Glutathion; Isethion; Tathion; Glutathione-SH; Glutinal; reduced glutathione; Neuthion; Deltathione; Copren; L-Glutathione reduced; Glutide; Tathione; Triptide; Ledac; Glutatione; GSH; Glutatiol; Panaron; gamma-L-Glutamyl-L-cysteinylglycine; Glutathione SH; L-Glutatione; Glutathione (reduced); Agifutol S; L-gamma-glutamyl-L-cysteinylglycine; gamma-L-glutamyl-L-cysteinyl-glycine; 5-L-Glutamyl-L-cysteinylglycine; Glutathione [JAN]; glutathione red; gamma-L-Glutamylcysteinylglycine; red. glutathione
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Approved [1]
Cross-matching ID
PubChem CID
124886
ChEBI ID
CHEMBL1543
CAS Number
CAS 70-18-8
TTD Drug ID
DMAHMT9
VARIDT Drug ID
DR00039
INTEDE Drug ID
DR2036

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug(s) Targeting Enzyme unspecific (Enz)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desoxyribonuclease DMEZFXR Female genital tract inflammation GA0Z Approved [22]
VT-1129 DMCGK9H Onchocerciasis 1F6A Phase 2 [23]
HTI-101 DMURXMJ Obesity 5B81 Phase 2 [24]
ASC-101 DMVNCSK Haematological malignancy 2B33.Y Phase 1/2 [25]
BXCL702 DMY9L4C Haematological malignancy 2B33.Y Phase 1 [26]
NZ-1002 DMINSRW Lysosomal storage disease 5C56.Z Terminated [27]
A-11259 DMZ5NQP Bacterial infection 1A00-1C4Z Terminated [28]
SRI-3072 DMBEUN6 Mycobacterium infection 1B10-1B21 Terminated [29]
GW-278884 DMUG82P Colorectal cancer 2B91.Z Terminated [30]
BM-13677 DMKITQN Diabetic complication 5A2Y Terminated [31]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Folic Acid DMEMBJC Colorectal carcinoma Approved [34]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [35]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Verapamil DMA7PEW Angina pectoris BA40 Approved [37]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [38]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [39]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [40]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [37]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [41]
Methotrexate DM2TEOL Anterior urethra cancer Approved [42]
Folic Acid DMEMBJC Colorectal carcinoma Approved [43]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [44]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [45]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [46]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [47]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [48]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [49]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [50]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [37]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Folic Acid DMEMBJC Colorectal carcinoma Approved [53]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [52]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [52]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [54]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [52]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [55]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [56]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [57]
Methotrexate DM2TEOL Anterior urethra cancer Approved [58]
Folic Acid DMEMBJC Colorectal carcinoma Approved [59]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [60]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [61]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [62]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [63]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [62]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [64]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [65]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [66]
Folic Acid DMEMBJC Colorectal carcinoma Approved [67]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [68]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [69]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [70]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [71]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [72]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [37]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [73]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [75]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [76]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [77]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [75]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [78]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [79]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [80]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [81]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [80]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
dehydroascorbic acid DMKYQO4 Discovery agent N.A. Investigative [9]
Drug Name Drug ID Indication ICD 11 Highest Status REF
dehydroascorbic acid DMKYQO4 Discovery agent N.A. Investigative [9]
Drug Name Drug ID Indication ICD 11 Highest Status REF
LTC4 DM702WR Discovery agent N.A. Investigative [11]
Glutathione ester DMAV2I7 N. A. N. A. Investigative [11]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
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Drug(s) Affected By Defensin beta 4A (DEFB4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [92]
Oxindole 94 DMPFD6Y Pain MG30-MG3Z Investigative [93]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Testosterone DM7HUNW Hot flushes GA30 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [100]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [102]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [103]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [105]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [106]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [110]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [108]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [114]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [115]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [117]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [115]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [118]
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Drug(s) Affected By C-C motif chemokine 20 (CCL20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [121]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [124]
Leflunomide DMR8ONJ Arthritis FA20 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [127]
Selenium DM25CGV N. A. N. A. Approved [128]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [129]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [130]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [133]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [134]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [135]
Fructose DM43AN2 Vomiting MD90 Approved [136]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [137]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [140]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [141]
Leflunomide DMR8ONJ Arthritis FA20 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [142]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [144]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Menthol DMG2KW7 Back pain ME84.Z Approved [145]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [147]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [148]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [149]
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Drug(s) Affected By Prothymosin alpha (PTMA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Methotrexate DM2TEOL Anterior urethra cancer Approved [151]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [152]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [154]
Haloperidol DM96SE0 Delirium Approved [155]
Testosterone enanthate DMB6871 N. A. N. A. Approved [156]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Clozapine DMFC71L Schizophrenia 6A20 Approved [155]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [157]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [158]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [68]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [84]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [160]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [88]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
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Drug(s) Affected By Riboflavin kinase (RFK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [163]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [144]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [164]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [165]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [165]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [118]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [166]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [167]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [168]
Arsenic DMTL2Y1 N. A. N. A. Approved [169]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [170]
Selenium DM25CGV N. A. N. A. Approved [171]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [172]
Epinephrine DM3KJBC Acute asthma CA23 Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [174]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [175]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [178]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [179]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [118]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [182]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [183]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Enalapril DMNFUZR Congestive heart failure BD10 Approved [184]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [185]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [186]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [188]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [189]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [190]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [190]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [191]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [192]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [193]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Gefitinib DM15F0X Colon adenocarcinoma Approved [195]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [196]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [197]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [198]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [199]
Methotrexate DM2TEOL Anterior urethra cancer Approved [200]
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Drug(s) Affected By Alpha-synuclein (SNCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Testosterone enanthate DMB6871 N. A. N. A. Approved [156]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [201]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [202]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [118]
Bortezomib DMNO38U Leukemia Approved [203]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [204]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [205]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [206]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [207]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [208]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [209]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [210]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [211]
Prednisone DM2HG4X Acute asthma CA23 Approved [212]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [213]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [214]
Methotrexate DM2TEOL Anterior urethra cancer Approved [200]
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Drug(s) Affected By Protein DEK (DEK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [152]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [215]
Testosterone DM7HUNW Hot flushes GA30 Approved [165]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [165]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [91]
Folic Acid DMEMBJC Colorectal carcinoma Approved [216]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [118]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Enzyme unspecific (Enz) TT3C1VN NOUNIPROTAC Modulator [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [3]
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [4]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [5]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [6]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [7]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [8]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glutathione S-transferase omega-2 (GSTO2) DEHMPZR GSTO2_HUMAN Substrate [9]
Glutathione S-transferase omega-1 (GSTO1) DEZSNJD GSTO1_HUMAN Substrate [9]
Glutathione peroxidase 6 (GPX6) DEOS3FD GPX6_HUMAN Substrate [10]
Gamma-glutamyltranspeptidase 5 (GGT5) DEH6CAO GGT5_HUMAN Substrate [11]
Gamma-glutamylcyclotransferase (GGCT) DEKW6PB A0A073ACX1_RALSL Substrate [12] , [13]
Gamma-glutamylcyclotransferase 2 (CHAC2) DEB4JZV CHAC2_HUMAN Substrate [14]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Post-Translational Modifications [15]
Alpha-synuclein (SNCA) OTPWC1MR SYUA_HUMAN Regulation of Drug Effects [16]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Regulation of Drug Effects [17]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Regulation of Drug Effects [17]
C-C motif chemokine 20 (CCL20) OTUCJY4N CCL20_HUMAN Gene/Protein Processing [18]
Defensin beta 4A (DEFB4A) OTQEI15K DFB4A_HUMAN Gene/Protein Processing [18]
Glutathione S-transferase Mu 2 (GSTM2) OTG4WT05 GSTM2_HUMAN Regulation of Drug Effects [19]
Glutathione S-transferase Mu 3 (GSTM3) OTLA2WJT GSTM3_HUMAN Regulation of Drug Effects [20]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [18]
Maleylacetoacetate isomerase (GSTZ1) OTQ43JCE MAAI_HUMAN Protein Interaction/Cellular Processes [21]

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