Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMNXI1E)

Drug Name
2-tert-butylbenzene-1,4-diol Drug Info
Synonyms
Tert-Butylhydroquinone; tert-Butylhydroquinone; 1948-33-0; TBHQ; 2-tert-Butylhydroquinone; T-BUTYLHYDROQUINONE; MTBHQ; t-Butyl hydroquinone; 2-tert-Butyl-1,4-benzenediol; 2-t-Butylhydroquinone; Mono-tert-butylhydroquinone; Sustane; Tenox TBHQ; tert-Butyl-1,4-benzenediol; Mono-tertiarybutylhydroquinone; Hydroquinone, tert-butyl-; Banox 20BA; 1,4-Benzenediol, 2-(1,1-dimethylethyl)-; tertiary-Butylhydroquinone; 2-(1,1-Dimethylethyl)-1,4-benzenediol; 2-tert-Butyl(1,4)hydroquinone; 2-(tert-butyl)benzene-1,4-diol
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
16043
ChEBI ID
CHEBI:78886
CAS Number
CAS 1948-33-0
TTD Drug ID
DMNXI1E

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Influenza Hemagglutinin (Influ HA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arbidol DMOQK8Z Virus infection 1A24-1D9Z Approved [8]
CR8020 DMQ47U6 Influenza virus infection 1E30-1E32 Phase 2 [9]
RG7745 DMK5PYS Infectious disease 1A00-CA43.1 Phase 2 [10]
VIS410 DM1G6ME Influenza A virus infection 1E30 Phase 2 [11]
ND-1.1 DMVQAEK Influenza virus infection 1E30-1E32 Phase 1 [12]
VGX-3400 DMGMEH7 Influenza A virus H5N1 infection 1E30 Phase 1 [13]
A/Anhui/05 DMGJ7A4 Influenza virus infection 1E30-1E32 Phase 1 [14]
VIR-2482 DM6LQIU Influenza A virus infection 1E30 Phase 1 [15]
Alpha-D-Mannose DMF5DLW Discovery agent N.A. Investigative [16]
BMY-27709 DMAMYWL Discovery agent N.A. Investigative [1]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [17]
Folic Acid DMEMBJC Colorectal carcinoma Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Quercetin DM3NC4M Obesity 5B81 Approved [6]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [20]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [21]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [22]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [23]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [24]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [24]
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Drug(s) Affected By ATP-binding cassette sub-family C member 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [25]
Sulfinpyrazone DMEV954 Gout FA25 Approved [26]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [27]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [29]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [30]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [32]
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Drug(s) Affected By Glutathione reductase, mitochondrial (GSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [33]
Ketoprofen DMRKXPT Bursitis Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [35]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [39]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [42]
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Drug(s) Affected By Glutathione S-transferase P (GSTP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [43]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [45]
Chlorambucil DMRKE63 Chronic lymphocytic leukaemia 2A82.0 Approved [45]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [46]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Selenium DM25CGV N. A. N. A. Approved [49]
Etretinate DM2CZFA Keratosis ED56 Approved [50]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [51]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [52]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [53]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [54]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [55]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [57]
Ethacrynic acid DM60QMR Edema MG29 Approved [58]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [59]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [60]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [61]
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Drug(s) Affected By GA-binding protein alpha chain (GABPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [62]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [65]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [66]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [68]
Milchsaure DM462BT Pruritus EC90 Investigative [69]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [70]
GW7604 DMCA4RM Discovery agent N.A. Investigative [62]
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Drug(s) Affected By T-lymphocyte activation antigen CD86 (CD86)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [72]
Kanamycin DM2DMPO Bacteremia 1A73 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [73]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [77]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [73]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [78]
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Drug(s) Affected By Kelch-like ECH-associated protein 1 (KEAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Selenium DM25CGV N. A. N. A. Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [81]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [82]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [83]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [83]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [85]
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Drug(s) Affected By Liver carboxylesterase 1 (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [86]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [87]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [88]
Selenium DM25CGV N. A. N. A. Approved [49]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [90]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [91]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
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Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [94]
Verapamil DMA7PEW Angina pectoris BA40 Approved [95]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [49]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [98]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [99]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [102]
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Drug(s) Affected By Glutathione S-transferase Mu 1 (GSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [43]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [103]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
Ethanol DMDRQZU Chronic pain MG30 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [106]
Methyldopa DM5I621 Hypertension BA00-BA04 Approved [107]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
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Drug(s) Affected By Hemoglobin subunit gamma-1 (HBG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone enanthate DMB6871 N. A. N. A. Approved [110]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [21]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [112]
Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [87]
Verapamil DMA7PEW Angina pectoris BA40 Approved [113]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [96]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [113]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [114]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [117]
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Drug(s) Affected By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [118]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [119]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [122]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [123]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [126]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [127]
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Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [129]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [130]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [131]
Capsaicin DMGMF6V Back pain ME84.Z Approved [132]
Zafirlukast DMHNQOG Asthma CA23 Approved [133]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [130]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [134]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [131]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [130]
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Drug(s) Affected By Transcription factor JunD (JUND)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [135]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [136]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [137]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [77]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [139]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [140]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [141]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [142]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [143]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [144]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [145]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [146]
Gefitinib DM15F0X Colon adenocarcinoma Approved [147]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [148]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [149]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [150]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [141]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [151]
Paclitaxel DMLB81S Breast carcinoma Approved [152]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [153]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [140]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [154]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [143]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [144]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [155]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [131]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [156]
Capsaicin DMGMF6V Back pain ME84.Z Approved [132]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [130]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [157]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [130]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [155]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [34]
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Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [158]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [159]
Selenium DM25CGV N. A. N. A. Approved [160]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [161]
Methotrexate DM2TEOL Anterior urethra cancer Approved [162]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [163]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [167]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [168]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Gefitinib DM15F0X Colon adenocarcinoma Approved [171]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Selenium DM25CGV N. A. N. A. Approved [49]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [174]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [175]
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Drug(s) Affected By Transcription regulator protein BACH1 (BACH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [178]
Leflunomide DMR8ONJ Arthritis FA20 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
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Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [181]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [182]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [183]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [92]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [184]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [185]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [186]
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Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [188]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [188]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [190]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [188]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [57]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
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Drug(s) Affected By Growth-regulated alpha protein (CXCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Selenium DM25CGV N. A. N. A. Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [193]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [194]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [195]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [106]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [196]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [197]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [198]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [199]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [200]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [135]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [201]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [188]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [202]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [188]
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Drug(s) Affected By C-C motif chemokine 5 (CCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [62]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [203]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [72]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [204]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [206]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [207]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 1 (DUSP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [210]
Methotrexate DM2TEOL Anterior urethra cancer Approved [211]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [212]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [213]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [214]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [216]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [217]
Diazepam DM08E9O Alcohol withdrawal Approved [218]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [217]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [217]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [220]
Ethacrynic acid DM60QMR Edema MG29 Approved [58]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-interleukin-16 (IL16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [221]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ethanol DMDRQZU Chronic pain MG30 Approved [223]
Menthol DMG2KW7 Back pain ME84.Z Approved [224]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [4]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [225]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor MafG (MAFG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [228]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [138]
Leflunomide DMR8ONJ Arthritis FA20 Approved [179]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [83]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [186]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Platelet-derived growth factor subunit B (PDGFB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [229]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [230]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [223]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [231]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ethanol DMDRQZU Chronic pain MG30 Approved [223]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-2 receptor subunit alpha (IL2RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [193]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [234]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [235]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [236]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [237]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [238]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [239]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [75]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Folic Acid DMEMBJC Colorectal carcinoma Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ferritin heavy chain (FTH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [241]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [242]
Methotrexate DM2TEOL Anterior urethra cancer Approved [193]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [243]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [244]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [245]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Selenium DM25CGV N. A. N. A. Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [100]
Epinephrine DM3KJBC Acute asthma CA23 Approved [246]
Quercetin DM3NC4M Obesity 5B81 Approved [247]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [194]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [39]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [248]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [212]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [249]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [250]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [251]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [252]
Paclitaxel DMLB81S Breast carcinoma Approved [253]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [254]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [255]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [256]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endothelin-1 (EDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [258]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [259]
Methotrexate DM2TEOL Anterior urethra cancer Approved [162]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [260]
Quercetin DM3NC4M Obesity 5B81 Approved [261]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [262]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [263]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Epoxide hydrolase 1 (EPHX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [265]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [138]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [266]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [267]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [215]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [268]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [65]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Sp1 (SP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [269]
Quercetin DM3NC4M Obesity 5B81 Approved [270]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [271]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [228]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [273]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [274]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [275]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [276]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [277]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [200]
Verapamil DMA7PEW Angina pectoris BA40 Approved [95]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [201]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Selenium DM25CGV N. A. N. A. Approved [278]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [279]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [280]
Methotrexate DM2TEOL Anterior urethra cancer Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [281]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [282]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [283]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [284]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [34]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Verapamil DMA7PEW Angina pectoris BA40 Approved [285]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [286]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [143]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [287]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [288]
Gefitinib DM15F0X Colon adenocarcinoma Approved [289]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [290]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [291]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [279]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-1,4-galactosyltransferase 1 (B4GALT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [296]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [297]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [65]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [298]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [299]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [299]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [299]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [300]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [301]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [242]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [99]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [302]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [303]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [304]
Selenium DM25CGV N. A. N. A. Approved [49]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [305]
Etretinate DM2CZFA Keratosis ED56 Approved [306]
Methotrexate DM2TEOL Anterior urethra cancer Approved [307]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [308]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [309]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [310]
Quercetin DM3NC4M Obesity 5B81 Approved [311]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-X-C motif chemokine 2 (CXCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [312]
Selenium DM25CGV N. A. N. A. Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [193]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [195]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [313]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [314]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [315]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [315]
Ethacrynic acid DM60QMR Edema MG29 Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [267]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [317]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [277]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [318]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [96]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [319]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [320]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [321]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [322]
Methotrexate DM2TEOL Anterior urethra cancer Approved [323]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Vascular endothelial growth factor receptor 2 (KDR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [324]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [325]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [326]
Haloperidol DM96SE0 Delirium Approved [327]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [296]
Clozapine DMFC71L Schizophrenia 6A20 Approved [327]
Menthol DMG2KW7 Back pain ME84.Z Approved [224]
Orlistat DMRJSP8 Obesity 5B81 Approved [328]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [329]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [330]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [331]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [65]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [332]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [333]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [334]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate--cysteine ligase catalytic subunit (GCLC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [335]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [37]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [336]
Quercetin DM3NC4M Obesity 5B81 Approved [337]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [338]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [339]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate--cysteine ligase regulatory subunit (GCLM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [340]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [341]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [342]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [343]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [344]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [345]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-2 (IL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sirolimus DMGW1ID Advanced cancer 2A00-2F9Z Approved [34]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [290]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [346]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [347]
Methotrexate DM2TEOL Anterior urethra cancer Approved [348]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [349]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [350]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [351]
Fentanyl DM8WAHT Analgesia MB40.8 Approved [352]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [237]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxidized low-density lipoprotein receptor 1 (OLR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [353]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [353]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [313]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [78]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [354]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [355]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [353]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [353]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [357]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 20 (CCL20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [201]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [358]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [195]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [78]
Leflunomide DMR8ONJ Arthritis FA20 Approved [179]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [359]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [154]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [360]
Gefitinib DM15F0X Colon adenocarcinoma Approved [361]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [362]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [363]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [364]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [365]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [366]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [367]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [368]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [368]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [369]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [370]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [368]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [368]
Ethacrynic acid DM60QMR Edema MG29 Approved [368]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Antigen peptide transporter 1 (TAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [312]
Selenium DM25CGV N. A. N. A. Approved [49]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [371]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [371]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [313]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [296]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 9 (TNFRSF9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [353]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [372]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [373]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [297]
Menthol DMG2KW7 Back pain ME84.Z Approved [224]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [375]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [376]
Gefitinib DM15F0X Colon adenocarcinoma Approved [377]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [378]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [379]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [136]
Methotrexate DM2TEOL Anterior urethra cancer Approved [162]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [380]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [381]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [382]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [383]
Arsenic DMTL2Y1 N. A. N. A. Approved [384]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [122]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [385]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tribbles homolog 3 (TRIB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [277]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [181]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [386]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [387]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [41]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [343]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [387]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [92]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [214]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [312]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [228]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [183]
Ethacrynic acid DM60QMR Edema MG29 Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [387]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [83]
Leflunomide DMR8ONJ Arthritis FA20 Approved [179]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [388]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [65]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [298]
Arsenic DMTL2Y1 N. A. N. A. Approved [389]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [122]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [390]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [391]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [392]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [392]
Gefitinib DM15F0X Colon adenocarcinoma Approved [393]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [34]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [394]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [395]
Methotrexate DM2TEOL Anterior urethra cancer Approved [396]
Quercetin DM3NC4M Obesity 5B81 Approved [397]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [398]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [399]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystine/glutamate transporter (SLC7A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [188]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [340]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [188]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [308]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Fluoxetine DM3PD2C Bipolar depression Approved [387]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein CREG2 (CREG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [400]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [78]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [401]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [402]
Milchsaure DM462BT Pruritus EC90 Investigative [69]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Influenza Hemagglutinin (Influ HA) TTF4CAM HEMA_I34A1 Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2) OTHTAM54 AAKG2_HUMAN Gene/Protein Processing [3]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [4]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [4]
Antigen peptide transporter 1 (TAP1) OTJL27PW TAP1_HUMAN Gene/Protein Processing [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Gene/Protein Processing [6]
Beta-1,4-galactosyltransferase 1 (B4GALT1) OTBCXEK7 B4GT1_HUMAN Gene/Protein Processing [3]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Gene/Protein Processing [7]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 20 (CCL20) OTUCJY4N CCL20_HUMAN Gene/Protein Processing [3]

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