Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBZIVP)

Drug Name
Tubocurarine Drug Info
Synonyms
Amelizol; Delacurarine; Jexin; Tubadil; Tubaine; Tubarine; Tubocurarin; Tubocurarinum; Chlorure de tubocurarine; Cloruro de tubocurarina; Dextrotubocurarine chloride; Intocostrine T; Isoquinoline alkaloid; Tubocurarina cloruro; Tubocurarina cloruro [DCIT]; Tubocurarine chloride; Tubocurarine hydrochloride; Tubocurarini chloridum; Chlorure de tubocurarine [INN-French]; Cloruro de tubocurarina [INN-Spanish]; Curarin-haf; D-Paracurarine chloride; D-Tubocurarine; D-Tubocurarine chloride; D-Tubocurarine dichloride; D-Tubocurarine hydrochloride; Delacurarine (TN); Jex (TN); Metubine (TN); Tubaine (TN); Tubarine (TN); Tubocurarine chloride (INN); Tubocurarine chloride (TN); Tubocurarine chloride (anhydrous); Tubocurarini chloridum [INN-Latin]; Tubocurarinum (TN); D-(+)-Tubocurarine chloride; Tubocurarine, chloride, hydrochloride, (+)-(8CI); D-7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium chloride; Tubocuraranium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, chloride, hydrochloride; (+)-Tubocurarine; (+)-Tubocurarine chloride; (+)-Tubocurarine chloride hydrochloride; 2,2',2'-trimethyl-6,6'-bis(methyloxy)tubocuraran-2,2'-diium-7',12'-diol dichloride; 7',12'-Dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium; 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium
Indication
Disease Entry ICD 11 Status REF
Anaesthesia 9A78.6 Approved [1]
Smoking dependence 6C4A.2 Approved [1]
Therapeutic Class
Neuromuscular Nondepolarizing Agents
Cross-matching ID
PubChem CID
6000
ChEBI ID
CHEBI:9774
CAS Number
CAS 57-95-4
TTD Drug ID
DMBZIVP
VARIDT Drug ID
DR00536

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Neuronal acetylcholine receptor alpha-2 (CHRNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rocuronium DMY9BMK Muscle spasm MB47.3 Approved [2]
Cisatracurium DMUZPJ5 Muscle spasm MB47.3 Approved [2]
Vecuronium DMP0UK2 Spasm MB47.3 Approved [2]
Levallorphan DMCOLUP Narcotic depression 6A7Z Approved [8]
Mivacurium DM473VD Anaesthesia 9A78.6 Approved [2]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [8]
Pipecuronium DM5F84A Spasm MB47.3 Approved [8]
CYTISINE DMUF0BJ Tobacco dependence 6C4A.2 Phase 3 [9]
CHOLINE DM5D9YK Insomnia 7A00-7A0Z Investigative [10]
[125I]epibatidine DMZWQH3 Discovery agent N.A. Investigative [11]
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Drug(s) Transported By Organic cation transporter 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [12]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [13]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [14]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [15]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [3]
Verapamil DMA7PEW Angina pectoris BA40 Approved [16]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [17]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [18]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [19]
Propranolol DM79NTF Angina pectoris BA40 Approved [20]
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Drug(s) Affected By Small conductance calcium-activated potassium channel protein 1 (KCNN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [23]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [24]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [25]
UCL1684 DMZNJFU Discovery agent N.A. Investigative [7]
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Drug(s) Affected By Dihydrofolate reductase (DHFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [30]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [31]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [32]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [33]
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Drug(s) Affected By Histone-lysine N-methyltransferase 2C (KMT2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [34]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ethanol DMDRQZU Chronic pain MG30 Approved [36]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [37]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [38]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [39]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [40]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [41]
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Drug(s) Affected By Fasciculation and elongation protein zeta-1 (FEZ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Aripiprazole DM3NUMH Bipolar I disorder Approved [43]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [44]
Panobinostat DM58WKG Chronic graft versus host disease Approved [45]
Testosterone enanthate DMB6871 N. A. N. A. Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [32]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [5]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [48]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [49]
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Drug(s) Affected By E3 ubiquitin-protein ligase parkin (PRKN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Emtricitabine DMBMUWZ Hepatitis virus infection 1E50-1E51 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ethanol DMDRQZU Chronic pain MG30 Approved [51]
Trifluoperazine DMKBYWI Anxiety Approved [52]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [53]
Methamphetamine DMPM4SK Anxiety Approved [54]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [55]
Arsenic DMTL2Y1 N. A. N. A. Approved [56]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [40]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [4]
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Drug(s) Affected By Complement component C7 (C7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Folic Acid DMEMBJC Colorectal carcinoma Approved [57]
Arsenic DMTL2Y1 N. A. N. A. Approved [58]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [59]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [4]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [60]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [24]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [61]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [62]
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Drug(s) Affected By Stress-induced-phosphoprotein 1 (STIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [63]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [64]
Haloperidol DM96SE0 Delirium Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [33]
Benzatropine DMF7EXL Parkinsonian disorder Approved [65]
Clozapine DMFC71L Schizophrenia 6A20 Approved [65]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [4]
Paclitaxel DMLB81S Breast carcinoma Approved [67]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [68]
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Drug(s) Affected By Son of sevenless homolog 1 (SOS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Selenium DM25CGV N. A. N. A. Approved [70]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [72]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [73]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [74]
Leflunomide DMR8ONJ Arthritis FA20 Approved [75]
Testosterone enanthate DMB6871 N. A. N. A. Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [76]
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Drug(s) Affected By Contactin-1 (CNTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [21]
Panobinostat DM58WKG Chronic graft versus host disease Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [33]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [5]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [49]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [78]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [5]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [60]
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Drug(s) Affected By Golgin subfamily A member 4 (GOLGA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Testosterone enanthate DMB6871 N. A. N. A. Approved [46]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [79]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [33]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [4]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [37]
Arsenic DMTL2Y1 N. A. N. A. Approved [80]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [4]
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Drug(s) Affected By Ninein (NIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [81]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [82]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [82]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [40]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
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Drug(s) Affected By Small conductance calcium-activated potassium channel protein 2 (KCNN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [77]
Testosterone DM7HUNW Hot flushes GA30 Approved [84]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [47]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [32]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [85]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [86]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [87]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [88]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Neuronal acetylcholine receptor alpha-2 (CHRNA2) TTF4E0J ACHA2_HUMAN Antagonist [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Complement component C7 (C7) OTZ27VJN CO7_HUMAN Gene/Protein Processing [4]
Contactin-1 (CNTN1) OT7RNPEY CNTN1_HUMAN Gene/Protein Processing [4]
Dihydrofolate reductase (DHFR) OT3DVIGM DYR_HUMAN Gene/Protein Processing [5]
E3 ubiquitin-protein ligase parkin (PRKN) OTJBN41W PRKN_HUMAN Gene/Protein Processing [4]
Fasciculation and elongation protein zeta-1 (FEZ1) OTWCXPRE FEZ1_HUMAN Gene/Protein Processing [5]
Golgin subfamily A member 4 (GOLGA4) OTCMEHNJ GOGA4_HUMAN Gene/Protein Processing [4]
Histone-lysine N-methyltransferase 2C (KMT2C) OTC59BCO KMT2C_HUMAN Gene/Protein Processing [5]
Ligand-gated cation channel ZACN OTI241FS ZACN_HUMAN Gene/Protein Processing [6]
Ninein (NIN) OTVH3M4Z NIN_HUMAN Gene/Protein Processing [4]
Small conductance calcium-activated potassium channel protein 1 (KCNN1) OT87X2EH KCNN1_HUMAN Gene/Protein Processing [7]

References

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21 Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling. PLoS One. 2013 May 28;8(5):e63862.
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29 Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
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33 Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
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58 Fetal-sex dependent genomic responses in the circulating lymphocytes of arsenic-exposed pregnant women in New Hampshire. Reprod Toxicol. 2017 Oct;73:184-195. doi: 10.1016/j.reprotox.2017.07.023. Epub 2017 Aug 6.
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