General Information of Drug (ID: DMJNQ9K)

Drug Name
Octanedioic acid bis-hydroxyamide Drug Info
Synonyms Suberohydroxamic acid
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5173
ChEBI ID
CHEBI:125584
TTD Drug ID
DMJNQ9K

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Approved Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Citarinostat DMQLODU Multiple myeloma 2A83 Phase 1 [4]
KA2507 DMW0H9Y Solid tumour/cancer 2A00-2F9Z Phase 1 [4]
PMID29671355-Compound-62 DMWRS34 N. A. N. A. Patented [5]
PMID29671355-Compound-43 DMVPMWJ N. A. N. A. Patented [5]
PMID29671355-Compound-25 DMPV0KZ N. A. N. A. Patented [5]
PMID29671355-Compound-21 DMPJN0M N. A. N. A. Patented [5]
PMID29671355-Compound-31 DM3H78D N. A. N. A. Patented [5]
PMID29671355-Compound-56 DM0VBMI N. A. N. A. Patented [5]
PMID29671355-Compound-67 DM1RPL4 N. A. N. A. Patented [5]
PMID29671355-Compound-23 DMUBOEX N. A. N. A. Patented [5]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
NBM-BMX DM5OWXA Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
PMID29671355-Compound-62 DMWRS34 N. A. N. A. Patented [5]
PMID29671355-Compound-43 DMVPMWJ N. A. N. A. Patented [5]
PMID29671355-Compound-25 DMPV0KZ N. A. N. A. Patented [5]
PMID29671355-Compound-21 DMPJN0M N. A. N. A. Patented [5]
PMID29671355-Compound-31 DM3H78D N. A. N. A. Patented [5]
PMID29671355-Compound-56 DM0VBMI N. A. N. A. Patented [5]
PMID29671355-Compound-67 DM1RPL4 N. A. N. A. Patented [5]
PMID29671355-Compound-23 DMUBOEX N. A. N. A. Patented [5]
PMID29671355-Compound-44 DM80A3V N. A. N. A. Patented [5]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
CHR-3996 DMIXPNG Lymphoma 2A80-2A86 Phase 1/2 [7]
PMID29671355-Compound-62 DMWRS34 N. A. N. A. Patented [5]
PMID29671355-Compound-43 DMVPMWJ N. A. N. A. Patented [5]
PMID29671355-Compound-25 DMPV0KZ N. A. N. A. Patented [5]
PMID29671355-Compound-21 DMPJN0M N. A. N. A. Patented [5]
PMID29671355-Compound-31 DM3H78D N. A. N. A. Patented [5]
PMID29671355-Compound-56 DM0VBMI N. A. N. A. Patented [5]
PMID29671355-Compound-67 DM1RPL4 N. A. N. A. Patented [5]
PMID29671355-Compound-23 DMUBOEX N. A. N. A. Patented [5]
PMID29671355-Compound-44 DM80A3V N. A. N. A. Patented [5]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID29671355-Compound-62 DMWRS34 N. A. N. A. Patented [5]
PMID29671355-Compound-43 DMVPMWJ N. A. N. A. Patented [5]
PMID29671355-Compound-25 DMPV0KZ N. A. N. A. Patented [5]
PMID29671355-Compound-21 DMPJN0M N. A. N. A. Patented [5]
PMID29671355-Compound-31 DM3H78D N. A. N. A. Patented [5]
PMID29671355-Compound-56 DM0VBMI N. A. N. A. Patented [5]
PMID29671355-Compound-67 DM1RPL4 N. A. N. A. Patented [5]
PMID29671355-Compound-23 DMUBOEX N. A. N. A. Patented [5]
PMID29671355-Compound-61 DMXH1G3 N. A. N. A. Patented [5]
PMID29671355-Compound-45a DM5LYKR N. A. N. A. Patented [5]
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Drug(s) Targeting Histone deacetylase (HDAC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [8]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [9]
HBI-8000 DMDWYUN Non-small-cell lung cancer 2C25.Y Registered [4]
ITF2357 DMFZBNE Duchenne dystrophy 8C70 Phase 3 [10]
Pracinostat DMTD7AB Acute myeloid leukaemia 2A60 Phase 3 [11]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [12]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [4]
CMS-024-02 DMC4X7L Solid tumour/cancer 2A00-2F9Z Phase 3 [13]
Abexinostat DM91LGU Follicular lymphoma 2A80 Phase 3 [14]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [15]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [16]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [17]
Panobinostat DM58WKG Chronic graft versus host disease Approved [16]
HBI-8000 DMDWYUN Non-small-cell lung cancer 2C25.Y Registered [15]
ITF2357 DMFZBNE Duchenne dystrophy 8C70 Phase 3 [18]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [19]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [12]
Phenylbutyrate DMBHPDW Urea cycle disorder 5C50.A Phase 2 [20]
MGCD-0103 DM726HX Non-small-cell lung cancer 2C25.Y Phase 2 [16]
Resminostat DMNE1FR Hepatocellular carcinoma 2C12.02 Phase 2 [21]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Testosterone DM7HUNW Hot flushes GA30 Approved [23]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [23]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [3]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [3]
Nabiximols DMHKJ5I Cancer related pain MG30 Phase 3 [25]
MGCD-0103 DM726HX Non-small-cell lung cancer 2C25.Y Phase 2 [3]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [26]
Tacedinaline DM1Z74X Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [3]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [3]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [29]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [3]
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Drug(s) Affected By Sestrin-3 (SESN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Capsaicin DMGMF6V Back pain ME84.Z Approved [41]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [42]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [43]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [46]
Leflunomide DMR8ONJ Arthritis FA20 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [45]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [48]
Ethanol DMDRQZU Chronic pain MG30 Approved [49]
Menthol DMG2KW7 Back pain ME84.Z Approved [50]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [43]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [3]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [53]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [54]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [54]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [55]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [56]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [60]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [3]
Urethane DM7NSI0 N. A. N. A. Phase 4 [61]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [62]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [63]
Leflunomide DMR8ONJ Arthritis FA20 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [24]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [3]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [3]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [65]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [66]
Urethane DM7NSI0 N. A. N. A. Phase 4 [61]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [67]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [68]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [65]
Arsenic DMTL2Y1 N. A. N. A. Approved [69]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [3]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [70]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
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Drug(s) Affected By Protein Jumonji (JARID2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [3]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [72]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [3]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [74]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
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Drug(s) Affected By ELL-associated factor 2 (EAF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Testosterone DM7HUNW Hot flushes GA30 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [3]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [78]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [79]
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Drug(s) Affected By Bcl-2-modifying factor (BMF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [81]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [82]
Leflunomide DMR8ONJ Arthritis FA20 Approved [47]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [83]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [85]
Menthol DMG2KW7 Back pain ME84.Z Approved [50]
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Drug(s) Affected By Sialidase-1 (NEU1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [86]
Fluoxetine DM3PD2C Bipolar depression Approved [87]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [88]
Arsenic DMTL2Y1 N. A. N. A. Approved [69]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [60]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [48]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [65]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [66]
Urethane DM7NSI0 N. A. N. A. Phase 4 [61]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [90]
Scriptaid DM9JZ21 Solid tumour/cancer 2A00-2F9Z Preclinical [3]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [91]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [93]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [68]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [3]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [78]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [65]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [94]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [3]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
Pracinostat DMTD7AB Acute myeloid leukaemia 2A60 Phase 3 [3]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [90]
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Drug(s) Affected By DmX-like protein 1 (DMXL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Panobinostat DM58WKG Chronic graft versus host disease Approved [3]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [95]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [57]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [96]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [97]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [65]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase (HDAC) TTBH0VX NOUNIPROTAC Inhibitor [2]
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [1]
Histone deacetylase 2 (HDAC2) TTSHTOI HDAC2_HUMAN Inhibitor [1]
Histone deacetylase 4 (HDAC4) TTTQGH8 HDAC4_HUMAN Inhibitor [1]
Histone deacetylase 6 (HDAC6) TT5ZKDI HDAC6_HUMAN Inhibitor [1]
Histone deacetylase 8 (HDAC8) TTT6LFV HDAC8_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
7SK snRNA methylphosphate capping enzyme (MEPCE) OTRBQEYP MEPCE_HUMAN Gene/Protein Processing [3]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase 5 activator 1 (CDK5R1) OTJELWK0 CD5R1_HUMAN Gene/Protein Processing [3]
DmX-like protein 1 (DMXL1) OTWVL31L DMXL1_HUMAN Gene/Protein Processing [3]
ELL-associated factor 2 (EAF2) OTSOET5L EAF2_HUMAN Gene/Protein Processing [3]
G-protein coupled receptor 183 (GPR183) OTRILX7G GP183_HUMAN Gene/Protein Processing [3]
INO80 complex subunit D (INO80D) OTY39R4P IN80D_HUMAN Gene/Protein Processing [3]
Pre-mRNA-splicing factor RBM22 (RBM22) OTFW0IGK RBM22_HUMAN Gene/Protein Processing [3]
Protein Jumonji (JARID2) OT14UM8H JARD2_HUMAN Gene/Protein Processing [3]
Putative POTE ankyrin domain family member M (POTEM) OT7L2HGH POTEM_HUMAN Gene/Protein Processing [3]

References

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11 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8365).
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13 US patent application no. 2012,0302,505, Cyclodextrin-based polymers for therapeutic delivery.
14 Phase 1 study of the oral histone deacetylase inhibitor abexinostat in patients with Hodgkin lymphoma, non-Hodgkin lymphoma, or chronic lymphocytic leukaemia. Invest New Drugs. 2015 Apr;33(2):423-31.
15 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
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17 Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
18 Emerging drugs for the therapy of primary and post essential thrombocythemia, post polycythemia vera myelofibrosis. Expert Opin Emerg Drugs. 2009 Sep;14(3):471-9.
19 NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma. Blood. 2003 Oct 1;102(7):2615-22.
20 Emerging disease-modifying therapies for the treatment of motor neuron disease/amyotropic lateral sclerosis. Expert Opin Emerg Drugs. 2007 May;12(2):229-52.
21 2011 Pipeline of 4SC AG.
22 Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. PLoS One. 2010 Dec 17;5(12):e14352. doi: 10.1371/journal.pone.0014352.
23 Effects of 1alpha,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells. Mol Cancer. 2011 May 18;10:58.
24 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
25 Clinical response to Nabiximols correlates with the downregulation of immune pathways in multiple sclerosis. Eur J Neurol. 2018 Jul;25(7):934-e70. doi: 10.1111/ene.13623. Epub 2018 Apr 16.
26 Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma. Oncotarget. 2014 May 15;5(9):2355-71.
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