Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMIAHVU)

Drug Name
2-deoxyglucose Drug Info
Synonyms
154-17-6; Deoxyglucose; 2-Deoxy-D-mannose; 2-Deoxy-D-arabinohexose; UNII-9G2MP84A8W; D-Arabino-hexose, 2-deoxy-; HSDB 5484; arabino-Hexose, 2-deoxy-; D-Glucose, 2-deoxy-; 9G2MP84A8W; (3R,4S,5R)-3,4,5,6-tetrahydroxyhexanal; AK-44445; 2 Deoxyglucose; 2 Deoxy D glucose; 2 Desoxy D glucose; D-arabino-2-desoxyhexose; d-2-glucodesose; D-2dGlc; deoxy-d-glucose, 2-; 2-DEOXYLGLUCOSE; 2-INNo-D-AEIIC; SCHEMBL7670; AC1L33KH; KSC175S5P; 4-01-00-04282 (Beilstein Handbook Reference); Jsp003004; CHEMBL2074932; CTK0H5957; MolPort-002-317-302; 2-deoxy-D-glucose
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Approved [1]
Cross-matching ID
PubChem CID
108223
CAS Number
CAS 154-17-6
TTD Drug ID
DMIAHVU
VARIDT Drug ID
DR00011

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Transported By Glucose transporter type 1, erythrocyte/brain (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [19]
D-glucose DMMG2TO Discovery agent N.A. Investigative [20]
dehydroascorbic acid DMKYQO4 Discovery agent N.A. Investigative [21]
Arsenite DMBCO4Q Discovery agent N.A. Investigative [22]
Drug(s) Transported By Glucose transporter type 14 (SLC2A14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
dehydroascorbic acid DMKYQO4 Discovery agent N.A. Investigative [9]
Drug(s) Transported By Glucose transporter type 7 (SLC2A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [6]
Drug(s) Transported By Sodium/glucose cotransporter 1 (SLC5A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fucose DMAHMSV N. A. N. A. Investigative [10]
Drug(s) Transported By Sodium/glucose cotransporter 4 (SLC5A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [2]
D-mannose DMT6X03 Discovery agent N.A. Investigative [2]
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [23]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [24]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [25]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Fluoxetine DM3PD2C Bipolar depression Approved [24]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [31]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [33]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Folic Acid DMEMBJC Colorectal carcinoma Approved [37]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [40]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [41]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [43]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [44]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Gefitinib DM15F0X Colon adenocarcinoma Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [48]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [49]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [50]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [49]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [51]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [52]
Methotrexate DM2TEOL Anterior urethra cancer Approved [53]
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Drug(s) Affected By Transmembrane protein 250 (TMEM250)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [54]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [55]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [14]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [58]
GALLICACID DM6Y3A0 Discovery agent N.A. Investigative [59]
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Drug(s) Affected By Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [62]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [63]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [64]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [67]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [68]
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Drug(s) Affected By SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [70]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [71]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [72]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [73]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [74]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [71]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [14]
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Drug(s) Affected By Serine protease HTRA2, mitochondrial (HTRA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [78]
Testosterone DM7HUNW Hot flushes GA30 Approved [79]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [68]
Bortezomib DMNO38U Leukemia Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [82]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [84]
Selenium DM25CGV N. A. N. A. Approved [85]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [86]
Etretinate DM2CZFA Keratosis ED56 Approved [87]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [89]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [90]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [91]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [93]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Gefitinib DM15F0X Colon adenocarcinoma Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Methotrexate DM2TEOL Anterior urethra cancer Approved [99]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [100]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [102]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [104]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [105]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [108]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
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Drug(s) Affected By Serpin B5 (SERPINB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [112]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [114]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [115]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [107]
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Drug(s) Affected By Collagenase 3 (MMP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [117]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [118]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [117]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [119]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [120]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [118]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [123]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [124]
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Drug(s) Affected By Max-interacting protein 1 (MXI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [114]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [114]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [126]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [127]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [114]
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Drug(s) Affected By Small ribosomal subunit protein eS6 (RPS6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [129]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [130]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [18]
Testosterone DM7HUNW Hot flushes GA30 Approved [132]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [133]
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [134]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
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Drug(s) Affected By Unconventional myosin-Ie (MYO1E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [14]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [68]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Arsenic DMTL2Y1 N. A. N. A. Approved [137]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
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Drug(s) Affected By Serine/threonine-protein kinase STK11 (STK11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Selenium DM25CGV N. A. N. A. Approved [85]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [141]
Arsenic DMTL2Y1 N. A. N. A. Approved [137]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [142]
APR-246 DMNFADH Ovarian cancer 2C73 Phase 2 [143]
GDC-0980/RG7422 DMF3MV1 Non-hodgkin lymphoma 2B33.5 Phase 2 [144]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [145]
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Drug(s) Affected By 7SK snRNA methylphosphate capping enzyme (MEPCE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [146]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [147]
Urethane DM7NSI0 N. A. N. A. Phase 4 [148]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [149]
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Drug(s) Affected By Transmembrane protein 87A (TMEM87A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [126]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [151]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [55]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [152]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
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Drug(s) Affected By Lipase member H (LIPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [153]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Arsenic DMTL2Y1 N. A. N. A. Approved [137]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [154]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [155]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [156]
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Drug(s) Affected By Small integral membrane protein 14 (SMIM14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [14]
Testosterone DM7HUNW Hot flushes GA30 Approved [79]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [14]
Ampicillin DMHWE7P Acute epiglottitis Approved [27]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [127]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [151]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
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Drug(s) Affected By Partner of Y14 and mago (PYM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Panobinostat DM58WKG Chronic graft versus host disease Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [68]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [34]
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Drug(s) Affected By Protein FAM117A (FAM117A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [159]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [160]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [161]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [163]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [164]
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Drug(s) Affected By E3 ubiquitin-protein ligase Jade-2 (JADE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Panobinostat DM58WKG Chronic graft versus host disease Approved [165]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [166]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [127]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [167]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [14]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [165]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [168]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [169]
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Drug(s) Affected By AP-5 complex subunit sigma-1 (AP5S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Panobinostat DM58WKG Chronic graft versus host disease Approved [14]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [151]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [14]
Pracinostat DMTD7AB Acute myeloid leukaemia 2A60 Phase 3 [14]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch-like protein 42 (KLHL42)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [167]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [171]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [172]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [173]
Urethane DM7NSI0 N. A. N. A. Phase 4 [148]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [14]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inactive cell surface hyaluronidase CEMIP2 (CEMIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [68]
Folic Acid DMEMBJC Colorectal carcinoma Approved [174]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [151]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [136]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ERBB receptor feedback inhibitor 1 (ERRFI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [45]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [175]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [43]
Testosterone DM7HUNW Hot flushes GA30 Approved [79]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane and coiled-coil domain protein 3 (TMCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [79]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [178]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [72]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [173]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [178]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [173]
MGCD-0103 DM726HX Non-small-cell lung cancer 2C25.Y Phase 2 [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RING finger protein 24 (RNF24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Panobinostat DM58WKG Chronic graft versus host disease Approved [14]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [173]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [54]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [55]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-2-macroglobulin (A2M)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [180]
Prednisone DM2HG4X Acute asthma CA23 Approved [181]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [182]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [183]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [184]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Aminocaproic Acid DMFGND4 Bleeding disorder GA20-GA21 Approved [181]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Sodium/glucose cotransporter 4 (SLC5A9) DT1CP40 SC5A9_HUMAN Substrate [2]
Sodium/glucose cotransporter 3 (SLC5A4) DTO4FLB SC5A4_HUMAN Substrate [3]
Sodium/glucose cotransporter 5 (SLC5A10) DTQNIG7 SC5AA_HUMAN Substrate [3]
Glucose transporter type 12 (SLC2A12) DTA5QI0 GTR12_HUMAN Substrate [4]
Proton-associated sugar transporter A (SLC45A1) DTMSNOU S45A1_HUMAN Substrate [5]
Glucose transporter type 6 (SLC2A6) DTS4MKQ GTR6_HUMAN Substrate [6]
Glucose transporter type 4, insulin-responsive (SLC2A4) DT4827A GLUT4_HUMAN Substrate [7]
Glucose transporter type 3, brain (SLC2A3) DT9SQ3L GTR3_HUMAN Substrate [8]
Glucose transporter type 14 (SLC2A14) DT18YD9 GTR14_HUMAN Substrate [9]
Sodium/glucose cotransporter 1 (SLC5A1) DTOKC04 SC5A1_HUMAN Substrate [10]
Glucose transporter type 8 (SLC2A8) DT2I7BM GTR8_HUMAN Substrate [6]
Glucose transporter type 7 (SLC2A7) DT8SQBG GTR7_HUMAN Substrate [6]
Glucose transporter type 2, liver (SLC2A2) DTUJPOL GTR2_HUMAN Substrate [11]
Glucose transporter type 10 (SLC2A10) DT3BI6S GTR10_HUMAN Substrate [12]
Glucose transporter type 1, erythrocyte/brain (SLC2A1) DTG3T6X GTR1_HUMAN Substrate [13]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
7SK snRNA methylphosphate capping enzyme (MEPCE) OTRBQEYP MEPCE_HUMAN Gene/Protein Processing [14]
Alpha-2-macroglobulin (A2M) OTFTX90K A2MG_HUMAN Regulation of Drug Effects [15]
AP-5 complex subunit sigma-1 (AP5S1) OTGS53SC AP5S1_HUMAN Gene/Protein Processing [14]
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Gene/Protein Processing [16]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Gene/Protein Processing [17]
E3 ubiquitin-protein ligase Jade-2 (JADE2) OTVG2MYF JADE2_HUMAN Gene/Protein Processing [14]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Gene/Protein Processing [14]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Gene/Protein Processing [18]
Inactive cell surface hyaluronidase CEMIP2 (CEMIP2) OT9I1XUO CEIP2_HUMAN Gene/Protein Processing [14]
Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK) OTLF4ZB1 IKKA_HUMAN Protein Interaction/Cellular Processes [16]

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