Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM726HX)

Drug Name
MGCD-0103 Drug Info
Synonyms
Mocetinostat; MG 0103; MG 4230; MG 4915; MG 5026; MG0103; MG4230; MG4915; MG5206; MGCD 0103; MGCD0103; MG-0103; MG-4230; MG-4915; MG-5026; Mocetinostat, MGCD0103; N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide; N-(2-Aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Diffuse large B-cell lymphoma 2A81 Phase 1/2 [3]
Melanoma 2C30 Phase 1 [4]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
9865515
ChEBI ID
CHEBI:94525
CAS Number
CAS 726169-73-9
TTD Drug ID
DM726HX
VARIDT Drug ID
DR00735

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Histone deacetylase (HDAC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [9]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [10]
HBI-8000 DMDWYUN Non-small-cell lung cancer 2C25.Y Registered [1]
ITF2357 DMFZBNE Duchenne dystrophy 8C70 Phase 3 [11]
Pracinostat DMTD7AB Acute myeloid leukaemia 2A60 Phase 3 [12]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [13]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [1]
CMS-024-02 DMC4X7L Solid tumour/cancer 2A00-2F9Z Phase 3 [14]
Abexinostat DM91LGU Follicular lymphoma 2A80 Phase 3 [15]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [16]
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Drug(s) Targeting Histone deacetylase 1 (HDAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [5]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [17]
Panobinostat DM58WKG Chronic graft versus host disease Approved [5]
HBI-8000 DMDWYUN Non-small-cell lung cancer 2C25.Y Registered [16]
ITF2357 DMFZBNE Duchenne dystrophy 8C70 Phase 3 [18]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [19]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [13]
Phenylbutyrate DMBHPDW Urea cycle disorder 5C50.A Phase 2 [20]
Resminostat DMNE1FR Hepatocellular carcinoma 2C12.02 Phase 2 [21]
Sodium butyrate DMKNIVG Acute myeloid leukaemia 2A60 Phase 2 [22]
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Drug(s) Affected By Putative POTE ankyrin domain family member M (POTEM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Testosterone DM7HUNW Hot flushes GA30 Approved [24]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [24]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [7]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [7]
Nabiximols DMHKJ5I Cancer related pain MG30 Phase 3 [26]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [27]
Tacedinaline DM1Z74X Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [7]
Scriptaid DM9JZ21 Solid tumour/cancer 2A00-2F9Z Preclinical [7]
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Drug(s) Affected By Histone deacetylase 3 (HDAC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [30]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [31]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [35]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [36]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [38]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [39]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Selenium DM25CGV N. A. N. A. Approved [41]
Etretinate DM2CZFA Keratosis ED56 Approved [42]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
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Drug(s) Affected By G-protein coupled receptor 183 (GPR183)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Panobinostat DM58WKG Chronic graft versus host disease Approved [7]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [49]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [50]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [7]
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Drug(s) Affected By Signal transducer and activator of transcription 3 (STAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [53]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [57]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [58]
Methotrexate DM2TEOL Anterior urethra cancer Approved [59]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [60]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
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Drug(s) Affected By Histone H4 (H4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [63]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Selenium DM25CGV N. A. N. A. Approved [65]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [66]
Methotrexate DM2TEOL Anterior urethra cancer Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [67]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Panobinostat DM58WKG Chronic graft versus host disease Approved [8]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [70]
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Drug(s) Affected By Histone H3.1t (H3-4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [72]
Panobinostat DM58WKG Chronic graft versus host disease Approved [8]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [73]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [74]
Arsenic DMTL2Y1 N. A. N. A. Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [76]
Berberine DMC5Q8X N. A. N. A. Phase 4 [77]
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Drug(s) Affected By Borealin (CDCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [78]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [79]
Testosterone DM7HUNW Hot flushes GA30 Approved [24]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [24]
Leflunomide DMR8ONJ Arthritis FA20 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [82]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [83]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [84]
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Drug(s) Affected By Histone deacetylase 2 (HDAC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [88]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [30]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [90]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [91]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [40]
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Drug(s) Affected By Sialidase-1 (NEU1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [92]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Panobinostat DM58WKG Chronic graft versus host disease Approved [7]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [94]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [51]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [95]
Arsenic DMTL2Y1 N. A. N. A. Approved [96]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [97]
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Drug(s) Affected By PH and SEC7 domain-containing protein 3 (PSD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [100]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [101]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [102]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [32]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [103]
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Drug(s) Affected By Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [104]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [7]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [105]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [94]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [100]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [83]
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Drug(s) Affected By Programmed cell death 1 ligand 1 (CD274)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [66]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [108]
Testosterone DM7HUNW Hot flushes GA30 Approved [24]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [80]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [110]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
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Drug(s) Affected By ERBB receptor feedback inhibitor 1 (ERRFI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [63]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [111]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [24]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [24]
Leflunomide DMR8ONJ Arthritis FA20 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [25]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [7]
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Drug(s) Affected By Two pore channel protein 1 (TPCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [69]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [113]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [113]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [113]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [113]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [113]
Arsenic DMTL2Y1 N. A. N. A. Approved [96]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [114]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [115]
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Drug(s) Affected By Transmembrane and coiled-coil domain protein 3 (TMCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [24]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [24]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [117]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [7]
Bleomycin DMNER5S Cervical cancer 2C77.0 Approved [7]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [118]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [119]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [117]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [119]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase (HDAC) TTBH0VX NOUNIPROTAC Inhibitor [1]
Histone deacetylase 1 (HDAC1) TT6R7JZ HDAC1_HUMAN Inhibitor [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Borealin (CDCA8) OT17D55D BOREA_HUMAN Gene/Protein Processing [6]
Ceramide glucosyltransferase OTRT5P5I CEGT_HUMAN Gene/Protein Processing [7]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Gene/Protein Processing [6]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Gene/Protein Processing [7]
G-protein coupled receptor 183 (GPR183) OTRILX7G GP183_HUMAN Gene/Protein Processing [7]
Histone deacetylase 2 (HDAC2) OTUYVFKN HDAC2_HUMAN Gene/Protein Processing [6]
Histone deacetylase 3 (HDAC3) OTC6GUV3 HDAC3_HUMAN Gene/Protein Processing [6]
Histone H3.1t (H3-4) OTY6ITYF H31T_HUMAN Post-Translational Modifications [8]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Post-Translational Modifications [8]
PH and SEC7 domain-containing protein 3 (PSD3) OTTN9B9O PSD3_HUMAN Gene/Protein Processing [7]

References

1 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 Protein methyltransferases as a target class for drug discovery. Nat Rev Drug Discov. 2009 Sep;8(9):724-32.
6 Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells. Oncotarget. 2015 Oct 20;6(32):33623-35. doi: 10.18632/oncotarget.5601.
7 Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
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9 Transcription-independent heritability of induced histone modifications in the mouse preimplantation embryo. PLoS One. 2009 Jun 30;4(6):e6086.
10 Histone Deacetylase inhibitors: new promise in the treatment of immune and inflammatory diseases. Curr Drug Targets. 2010 Nov;11(11):1430-8.
11 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
12 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8365).
13 Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
14 US patent application no. 2012,0302,505, Cyclodextrin-based polymers for therapeutic delivery.
15 Phase 1 study of the oral histone deacetylase inhibitor abexinostat in patients with Hodgkin lymphoma, non-Hodgkin lymphoma, or chronic lymphocytic leukaemia. Invest New Drugs. 2015 Apr;33(2):423-31.
16 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
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18 Emerging drugs for the therapy of primary and post essential thrombocythemia, post polycythemia vera myelofibrosis. Expert Opin Emerg Drugs. 2009 Sep;14(3):471-9.
19 NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma. Blood. 2003 Oct 1;102(7):2615-22.
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23 Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. PLoS One. 2010 Dec 17;5(12):e14352. doi: 10.1371/journal.pone.0014352.
24 Effects of 1alpha,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells. Mol Cancer. 2011 May 18;10:58.
25 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
26 Clinical response to Nabiximols correlates with the downregulation of immune pathways in multiple sclerosis. Eur J Neurol. 2018 Jul;25(7):934-e70. doi: 10.1111/ene.13623. Epub 2018 Apr 16.
27 Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma. Oncotarget. 2014 May 15;5(9):2355-71.
28 Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity. Blood. 2007 May 15;109(10):4450-60.
29 Delta9-tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcription. Mol Hum Reprod. 2006 May;12(5):321-33. doi: 10.1093/molehr/gal036. Epub 2006 Apr 5.
30 Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
31 Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer. Cell Biol Toxicol. 2023 Oct;39(5):1873-1896. doi: 10.1007/s10565-021-09673-2. Epub 2022 Jan 1.
32 Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper. Physiol Genomics. 2009 Aug 7;38(3):386-401.
33 Effects of chronic exposure to arsenic and estrogen on epigenetic regulatory genes expression and epigenetic code in human prostate epithelial cells. PLoS One. 2012;7(8):e43880. doi: 10.1371/journal.pone.0043880. Epub 2012 Aug 27.
34 Bringing in vitro analysis closer to in vivo: studying doxorubicin toxicity and associated mechanisms in 3D human microtissues with PBPK-based dose modelling. Toxicol Lett. 2018 Sep 15;294:184-192.
35 Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines. Anticancer Drugs. 2005 Jul;16(6):635-43. doi: 10.1097/00001813-200507000-00008.
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37 Cannabidiol-induced transcriptomic changes and cellular senescence in human Sertoli cells. Toxicol Sci. 2023 Feb 17;191(2):227-238. doi: 10.1093/toxsci/kfac131.
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41 Selenite and selenomethionine promote HL-60 cell cycle progression. J Nutr. 2002 Apr;132(4):674-9. doi: 10.1093/jn/132.4.674.
42 Bexarotene activates the p53/p73 pathway in human cutaneous T-cell lymphoma. Br J Dermatol. 2009 Mar;160(3):519-26. doi: 10.1111/j.1365-2133.2008.08931.x. Epub 2008 Nov 25.
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