Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM8EU0Z)

Drug Name
Dicloxacillin Drug Info
Synonyms
Dichloroxacillin; Diclossacillina; Dicloxaciclin; Dicloxacilin; Dicloxacilina; Dicloxacilline; Dicloxacillinum; Dicloxacycline; Dycill; Dynapen; Maclicine; Methyldichlorophenylisoxazolylpenicillin; Pathocil; Diclossacillina [DCIT]; Dicloxacillin sodium; BRL 1702; Diclocil (TN); Dicloxacilina [INN-Spanish]; Dicloxacilline [INN-French]; Dicloxacillinum [INN-Latin]; R-13423; Dicloxacillin (USAN/INN); Dicloxacillin [USAN:INN:BAN]; Dicloxacillin, Monosodium Salt, Mono-Hydrate; (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin; 6-(3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; 6-(3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid; 6beta-{[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carboxamido}-2,2-dimethylpenam-3alpha-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Bacterial infection 1A00-1C4Z Approved [1]
Staphylococcal pneumonia Approved [2]
Staphylococcus aureus infection Approved [2]
Therapeutic Class
Antibiotics
Cross-matching ID
PubChem CID
18381
ChEBI ID
CHEBI:4511
CAS Number
CAS 3116-76-5
TTD Drug ID
DM8EU0Z
VARIDT Drug ID
DR00455
ACDINA Drug ID
D00193

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Penicillin binding protein (Bact PBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ampicillin DMHWE7P Acute epiglottitis Approved [11]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [12]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [13]
Ticarcillin DM4ME02 Aspiration pneumonia Approved [14]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [15]
Meropenem DM62UHC Bacterial infection 1A00-1C4Z Approved [13]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [16]
Clofarabine DMCVJ86 Acute lymphoblastic leukaemia 2A85 Approved [17]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [18]
Carbenicillin DMLEDNK Infection of the upper and lower urinary tract GC08 Approved [19]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [20]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [26]
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Drug(s) Transported By Peptide transporter 1 (SLC15A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [27]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [28]
Ampicillin DMHWE7P Acute epiglottitis Approved [29]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [30]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [31]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [32]
Ceftriaxone DMCEW64 Acute gonococcal cervicitis Approved [33]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [28]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [30]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [30]
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Drug(s) Transported By Peptide transporter 2 (SLC15A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [27]
Ampicillin DMHWE7P Acute epiglottitis Approved [4]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [34]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [35]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [36]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [4]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [37]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [27]
Aminolevulinic acid hci DMS4BLQ Acne vulgaris ED80 Approved [38]
Spirapril DM5XLTY Hypertension BA00-BA04 Approved [39]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [8]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [40]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [41]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [42]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [43]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [44]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [45]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [46]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [47]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [48]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [49]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [51]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [52]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [53]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [53]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [54]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [55]
Capsaicin DMGMF6V Back pain ME84.Z Approved [56]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [57]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [6]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [58]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [58]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [59]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [6]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [58]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [60]
Gefitinib DM15F0X Colon adenocarcinoma Approved [6]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [61]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [6]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [9]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [9]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [62]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [63]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [64]
Etidronic acid DM1XHYJ Bone Paget disease Approved [9]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [9]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [9]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [65]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [66]
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Drug(s) Affected By Protein S100-A8 (S100A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [10]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [67]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [70]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [10]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Penicillin binding protein (Bact PBP) TTJP4SM NOUNIPROTAC Binder [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Peptide transporter 2 (SLC15A2) DT8QKNP S15A2_HUMAN Substrate [4]
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [4]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [6]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [7]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Gene/Protein Processing [8]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Gene/Protein Processing [9]
Protein S100-A8 (S100A8) OTVMOB3F S10A8_HUMAN Gene/Protein Processing [10]

References

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2 Dicloxacillin FDA Label
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