Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMVRLT7)

Drug Name
Fludarabine Drug Info
Synonyms
FaraA; Fludarabina; Fludarabinum; Fluradosa; Fludarabina [Spanish]; Fludarabine [INN]; Fludarabinum [Latin]; SQ Fludarabine; Fludara, Fludarabine; Fludarabine (INN); Fluradosa (TN); F-Ara-A; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-F-ara-A; 2-Fluoro Ara-A; 2-Fluoro-9-beta-D-arabinofuranosyladenine; 9-beta-D-Arabinofuranosyl-2-fluoroadenine; 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine; 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-(9CI)
Indication
Disease Entry ICD 11 Status REF
Acute myelogenous leukaemia 2A41 Approved [1]
Cutaneous melanoma 2C30 Approved [1]
Haematological malignancy 2B33.Y Approved [2]
Hematologic disease 3C0Z Approved [1]
Hepatosplenic T-cell lymphoma Approved [1]
Immunodeficiency 4A00-4A85 Approved [1]
Large granular lymphocytic leukemia 2A90.1 Approved [1]
Lung cancer 2C25.0 Approved [1]
MALT lymphoma Approved [1]
Multiple sclerosis 8A40 Approved [1]
Myeloproliferative neoplasm 2A20 Approved [1]
Nodal marginal zone lymphoma 2A85.0 Approved [1]
Primary cutaneous peripheral T-cell lymphoma not otherwise specified Approved [1]
Recurrent adult burkitt lymphoma 2A85.6 Approved [1]
Small intestine lymphoma Approved [1]
Splenic marginal zone lymphoma Approved [1]
Systemic lupus erythematosus 4A40.0 Approved [1]
Systemic sclerosis 4A42 Approved [1]
Testicular lymphoma Approved [1]
Classic Hodgkin lymphoma Investigative [1]
Colon cancer 2B90.Z Investigative [1]
Gastric cancer 2B72 Investigative [1]
Neuroblastoma 2D11.2 Investigative [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
657237
ChEBI ID
CHEBI:94701
CAS Number
CAS 21679-14-1
TTD Drug ID
DMVRLT7
VARIDT Drug ID
DR00434

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adenosine deaminase (ADA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [11]
Elapegademase DMS7OU8 Adenosine deaminase defciency 4A01.1 Approved [12]
Pentostatin DM0HXDS Acute graft versus host disease 4B24.0 Approved [3]
GSK2696273 DMP5O1U Chronic pain MG30 Preregistration [13]
OTL-101 DMLMS6J Severe combined immunodeficiency 4A01.10 Phase 3 [14]
Ex vivo adenosine deaminase-transduced hematopoietic stem cell therapy DMIREUZ Immunodeficiency 4A00-4A85 Phase 1/2 [13]
EHNA DM014WS Discovery agent N.A. Investigative [15]
3-(6-Amino-purin-9-yl)-6-phenyl-hexan-2-ol DMZT8QX Discovery agent N.A. Investigative [16]
3-(6-Amino-purin-9-yl)-8-phenyl-octan-2-ol DMAIS1D Discovery agent N.A. Investigative [16]
1-Deaza-Adenosine DMG0VN6 Discovery agent N.A. Investigative [17]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [21]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [22]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [23]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [24]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [25]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [26]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [27]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [28]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [29]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [31]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [32]
Selenium DM25CGV N. A. N. A. Approved [33]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [28]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [34]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [39]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [40]
Paclitaxel DMLB81S Breast carcinoma Approved [41]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [42]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
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Drug(s) Affected By Proliferating cell nuclear antigen (PCNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Selenium DM25CGV N. A. N. A. Approved [49]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [50]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [51]
Meloxicam DM2AR7L Arthritis FA20 Approved [52]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Epinephrine DM3KJBC Acute asthma CA23 Approved [54]
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Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [55]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [56]
Gefitinib DM15F0X Colon adenocarcinoma Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Selenium DM25CGV N. A. N. A. Approved [59]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [60]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [5]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Selenium DM25CGV N. A. N. A. Approved [66]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [67]
Etretinate DM2CZFA Keratosis ED56 Approved [68]
Methotrexate DM2TEOL Anterior urethra cancer Approved [69]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [70]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [71]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [72]
Quercetin DM3NC4M Obesity 5B81 Approved [73]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [74]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Epinephrine DM3KJBC Acute asthma CA23 Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [80]
Fructose DM43AN2 Vomiting MD90 Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [82]
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Drug(s) Affected By DNA cytosine-5)-methyltransferase 1 (DNMT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [83]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [84]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [86]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [87]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [88]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [89]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [91]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [92]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [94]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [95]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [96]
Gefitinib DM15F0X Colon adenocarcinoma Approved [97]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [100]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [91]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [101]
Paclitaxel DMLB81S Breast carcinoma Approved [102]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [103]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [104]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [94]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [105]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [106]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [107]
Gefitinib DM15F0X Colon adenocarcinoma Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [110]
Selenium DM25CGV N. A. N. A. Approved [66]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [50]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [111]
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Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [115]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [117]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [118]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [120]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [121]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [122]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [123]
Gefitinib DM15F0X Colon adenocarcinoma Approved [124]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Etretinate DM2CZFA Keratosis ED56 Approved [126]
Prednisone DM2HG4X Acute asthma CA23 Approved [127]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [128]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [28]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [129]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [130]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [131]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [40]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [132]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [133]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [134]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [135]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [136]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [137]
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Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [9]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [142]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [143]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
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Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [145]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [146]
Ethacrynic acid DM60QMR Edema MG29 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [148]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [149]
Testosterone DM7HUNW Hot flushes GA30 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [151]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [120]
Menthol DMG2KW7 Back pain ME84.Z Approved [152]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [76]
Selenium DM25CGV N. A. N. A. Approved [66]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [154]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [155]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [157]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [158]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [74]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [159]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [160]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [161]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [162]
Ethacrynic acid DM60QMR Edema MG29 Approved [163]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [164]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [165]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [166]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Gefitinib DM15F0X Colon adenocarcinoma Approved [167]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [168]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [76]
Selenium DM25CGV N. A. N. A. Approved [66]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [169]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
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Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [171]
Prednisone DM2HG4X Acute asthma CA23 Approved [172]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [172]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [173]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [174]
Epinephrine DM3KJBC Acute asthma CA23 Approved [54]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Fluoxetine DM3PD2C Bipolar depression Approved [175]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [176]
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Drug(s) Affected By Bcl-2-binding component 3, isoforms 3/4 (BBC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [76]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [178]
Methotrexate DM2TEOL Anterior urethra cancer Approved [69]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [179]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [161]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [180]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [182]
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Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [28]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [178]
Quercetin DM3NC4M Obesity 5B81 Approved [184]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [185]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [186]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [186]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [188]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adenosine deaminase (ADA) TTLP57V ADA_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [7]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [8]
DNA cytosine-5)-methyltransferase 1 (DNMT1) OTM2DGTK DNMT1_HUMAN Gene/Protein Processing [9]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) OT4Y9NQI MP2K1_HUMAN Gene/Protein Processing [10]
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) OTUE7Z91 MP2K2_HUMAN Gene/Protein Processing [10]
Growth/differentiation factor 15 (GDF15) OTWQN50N GDF15_HUMAN Gene/Protein Processing [8]

References

1 Fludarabine FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4802).
3 Purine nucleoside analogs in indolent non-Hodgkin's lymphoma. Oncology (Williston Park). 2000 Jun;14(6 Suppl 2):13-5.
4 MDM2 antagonists activate p53 and synergize with genotoxic drugs in B-cell chronic lymphocytic leukemia cells. Blood. 2006 May 15;107(10):4109-14. doi: 10.1182/blood-2005-08-3273. Epub 2006 Jan 26.
5 Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide. PLoS One. 2014 Jun 23;9(6):e99993. doi: 10.1371/journal.pone.0099993. eCollection 2014.
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