Details of the Drug Combination

General Information of Drug Combination (ID: DC2ITL1)

• Drug Combination Name: Fulvestrant + Methotrexate
• Indication: Invasive ductal carcinoma; Status: Investigative [1]
• Component Drugs:
  Fulvestrant (DM0YZC6): Small molecular drug
  Methotrexate (DM2TEOL): Small molecular drug
• High-throughput Screening Result:
  Testing Cell Line: T-47D
  Zero Interaction Potency (ZIP) Score: 5.93
  Bliss Independence Score: 6.79
  Loewe Additivity Score: 8.72
  LHighest Single Agent (HSA) Score: 4.18

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Fulvestrant

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Approved	[2]

Fulvestrant Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Estrogen receptor (ESR)	TTZAYWL	ESR1_HUMAN	Antagonist	[18]

Fulvestrant Interacts with 2 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 3A4 (CYP3A4)	DE4LYSA	CP3A4_HUMAN	Metabolism	[19]
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DEYGVN4	UD11_HUMAN	Metabolism	[20]

Fulvestrant Interacts with 985 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Superoxide dismutase (SOD1)	OT39TA1L	SODC_HUMAN	Increases Expression	[11]
Transferrin receptor protein 1 (TFRC)	OT8ZPBDL	TFR1_HUMAN	Increases Expression	[11]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[11]
Integrin beta-1 (ITGB1)	OT6G1IAR	ITB1_HUMAN	Increases Expression	[11]
Macrophage colony-stimulating factor 1 (CSF1)	OT68M7RD	CSF1_HUMAN	Increases Expression	[11]
DNA topoisomerase 2-alpha (TOP2A)	OT6LPS08	TOP2A_HUMAN	Increases Expression	[11]
C-C motif chemokine 5 (CCL5)	OTSCA5CK	CCL5_HUMAN	Increases Expression	[11]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Increases Expression	[11]
Ephrin type-A receptor 1 (EPHA1)	OTGJMRZ0	EPHA1_HUMAN	Increases Expression	[11]
Proteinase-activated receptor 1 (F2R)	OT4WVWBO	PAR1_HUMAN	Increases Expression	[11]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[11]
Caspase-4 (CASP4)	OTVQTV1L	CASP4_HUMAN	Increases Expression	[11]
Dual specificity protein kinase CLK1 (CLK1)	OTG1LACW	CLK1_HUMAN	Increases Expression	[11]
Ras-related protein Rab-2A (RAB2A)	OT6SK83U	RAB2A_HUMAN	Increases Expression	[11]
CCHC-type zinc finger nucleic acid binding protein (CNBP)	OTTGM9NK	CNBP_HUMAN	Increases Expression	[11]
Dynein light chain 1, cytoplasmic (DYNLL1)	OTR69LHT	DYL1_HUMAN	Increases Expression	[11]
Paired box protein Pax-5 (PAX5)	OTYBJJWX	PAX5_HUMAN	Increases Expression	[11]
GA-binding protein alpha chain (GABPA)	OT9YB2SA	GABPA_HUMAN	Increases Expression	[11]
Mitogen-activated protein kinase kinase kinase 11 (MAP3K11)	OT0EYZAY	M3K11_HUMAN	Increases Expression	[11]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Increases Expression	[10]
ATP-binding cassette sub-family C member 5 (ABCC5)	OT34G4US	MRP5_HUMAN	Decreases Expression	[10]
Transforming acidic coiled-coil-containing protein 1 (TACC1)	OTGX20TE	TACC1_HUMAN	Increases Expression	[10]
Cystatin-A (CSTA)	OT1K68KE	CYTA_HUMAN	Decreases Expression	[10]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Decreases Expression	[10]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[10]
Receptor tyrosine-protein kinase erbB-2 (ERBB2)	OTOAUNCK	ERBB2_HUMAN	Increases Expression	[10]
Proliferating cell nuclear antigen (PCNA)	OTHZ1RIA	PCNA_HUMAN	Decreases Expression	[10]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[10]
Ephrin-A1 (EFNA1)	OTU2NUA2	EFNA1_HUMAN	Increases Expression	[10]
Insulin-like growth factor-binding protein 4 (IGFBP4)	OT2HZRBD	IBP4_HUMAN	Decreases Expression	[10]
Insulin receptor substrate 1 (IRS1)	OTNO82CU	IRS1_HUMAN	Decreases Expression	[10]
CCN family member 3 (CCN3)	OTOW5YL4	CCN3_HUMAN	Increases Expression	[10]
Matrix metalloproteinase-15 (MMP15)	OT1XF517	MMP15_HUMAN	Increases Expression	[10]
Neprilysin (MME)	OT5Q39P8	NEP_HUMAN	Increases Expression	[21]
Interferon alpha-inducible protein 6 (IFI6)	OTWOOAM4	IFI6_HUMAN	Increases Expression	[21]
Amphiregulin (AREG)	OTJFOR67	AREG_HUMAN	Decreases Expression	[21]
Trefoil factor 3 (TFF3)	OTJJDRTU	TFF3_HUMAN	Decreases Expression	[21]
Interferon-related developmental regulator 1 (IFRD1)	OT4SQMLQ	IFRD1_HUMAN	Decreases Expression	[12]
26S proteasome non-ATPase regulatory subunit 14 (PSMD14)	OTJWHMZ5	PSDE_HUMAN	Decreases Expression	[12]
Aurora kinase A (AURKA)	OTMX0HYT	AURKA_HUMAN	Decreases Expression	[12]
Protein phosphatase 1D (PPM1D)	OT8NLZ9D	PPM1D_HUMAN	Decreases Expression	[12]
ATP-dependent RNA helicase DDX3Y (DDX3Y)	OTKL1FNX	DDX3Y_HUMAN	Decreases Expression	[12]
Asparagine--tRNA ligase, cytoplasmic (NARS1)	OTFS4J1W	SYNC_HUMAN	Decreases Expression	[12]
Trafficking kinesin-binding protein 2 (TRAK2)	OTXVA7FN	TRAK2_HUMAN	Decreases Expression	[12]
Calsyntenin-1 (CLSTN1)	OTQN35G2	CSTN1_HUMAN	Decreases Expression	[12]
Kinesin-like protein KIF20A (KIF20A)	OTXOQHE0	KI20A_HUMAN	Decreases Expression	[12]
Apolipoprotein D (APOD)	OTT77XW8	APOD_HUMAN	Increases Expression	[12]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)	OTM0GDTP	IF2A_HUMAN	Decreases Expression	[12]
Nucleophosmin (NPM1)	OTTBYYT0	NPM_HUMAN	Decreases Expression	[12]
Heat shock protein HSP 90-beta (HSP90AB1)	OTR69EG7	HS90B_HUMAN	Decreases Expression	[12]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Decreases Expression	[12]
Matrix Gla protein (MGP)	OTZWU3FU	MGP_HUMAN	Decreases Expression	[12]
High mobility group protein B1 (HMGB1)	OT4B7CPF	HMGB1_HUMAN	Decreases Expression	[12]
Pro-cathepsin H (CTSH)	OTLFL0DG	CATH_HUMAN	Increases Expression	[12]
60 kDa heat shock protein, mitochondrial (HSPD1)	OTTO1Y11	CH60_HUMAN	Decreases Expression	[12]
Heat shock cognate 71 kDa protein (HSPA8)	OTJI2RCI	HSP7C_HUMAN	Decreases Expression	[12]
DNA topoisomerase 1 (TOP1)	OT51O0CF	TOP1_HUMAN	Decreases Expression	[12]
Endoplasmin (HSP90B1)	OT02XLBR	ENPL_HUMAN	Decreases Expression	[12]
Stathmin (STMN1)	OTDJ4RV0	STMN1_HUMAN	Decreases Expression	[12]
Protein SON (SON)	OT9VWV18	SON_HUMAN	Decreases Expression	[12]
Nucleolin (NCL)	OTBXPKMP	NUCL_HUMAN	Decreases Expression	[12]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)	OTBZKX4P	ROA2_HUMAN	Decreases Expression	[12]
Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1)	OTGP6GA4	NR4A1_HUMAN	Increases Expression	[12]
Splicing factor, proline- and glutamine-rich (SFPQ)	OTLCIAPJ	SFPQ_HUMAN	Decreases Expression	[12]
Ribonucleoside-diphosphate reductase large subunit (RRM1)	OTXGQOR9	RIR1_HUMAN	Decreases Expression	[12]
Signal transducer CD24 (CD24)	OT7CODJ4	CD24_HUMAN	Increases Expression	[12]
Threonine--tRNA ligase 1, cytoplasmic (TARS1)	OT0PWST5	SYTC_HUMAN	Decreases Expression	[12]
DNA-directed RNA polymerase II subunit RPB2 (POLR2B)	OTS3F0H2	RPB2_HUMAN	Decreases Expression	[12]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1)	OTFRWOLM	HNRH1_HUMAN	Decreases Expression	[12]
Heat shock 70 kDa protein 4 (HSPA4)	OT5HR0AR	HSP74_HUMAN	Decreases Expression	[12]
Thrombospondin-2 (THBS2)	OTXET551	TSP2_HUMAN	Decreases Expression	[12]
Coatomer subunit beta' (COPB2)	OT82JIGC	COPB2_HUMAN	Decreases Expression	[12]
Lamina-associated polypeptide 2, isoform alpha (TMPO)	OTL68EL4	LAP2A_HUMAN	Decreases Expression	[12]
Signal transducer and activator of transcription 1-alpha/beta (STAT1)	OTLMBUZ6	STAT1_HUMAN	Decreases Expression	[12]
Matrin-3 (MATR3)	OTESJ5S7	MATR3_HUMAN	Decreases Expression	[12]
Ras GTPase-activating-like protein IQGAP1 (IQGAP1)	OTZRWTGA	IQGA1_HUMAN	Decreases Expression	[12]
Histone H3-like centromeric protein A (CENPA)	OT0NEJ4X	CENPA_HUMAN	Decreases Expression	[12]
Sulfate transporter (SLC26A2)	OTJNHNTO	S26A2_HUMAN	Decreases Expression	[12]
Importin subunit alpha-1 (KPNA2)	OTU7FOE6	IMA1_HUMAN	Decreases Expression	[12]
Eukaryotic translation initiation factor 5 (EIF5)	OT79PQUN	IF5_HUMAN	Decreases Expression	[12]
Ras-related protein Rap-1A (RAP1A)	OT5RH6TI	RAP1A_HUMAN	Decreases Expression	[12]
DNA-dependent protein kinase catalytic subunit (PRKDC)	OTJVS4EG	PRKDC_HUMAN	Decreases Expression	[12]
Chromobox protein homolog 1 (CBX1)	OT2L4XZX	CBX1_HUMAN	Decreases Expression	[12]
Heterogeneous nuclear ribonucleoprotein U (HNRNPU)	OTLQN1E2	HNRPU_HUMAN	Decreases Expression	[12]
Large ribosomal subunit protein eL6 (RPL6)	OTRU71O4	RL6_HUMAN	Decreases Expression	[12]
DNA topoisomerase 2-beta (TOP2B)	OTDHKQZ8	TOP2B_HUMAN	Decreases Expression	[12]
Serine/arginine-rich splicing factor 1 (SRSF1)	OTF61HOV	SRSF1_HUMAN	Decreases Expression	[12]
ATP-dependent RNA helicase A (DHX9)	OT5AAOQI	DHX9_HUMAN	Decreases Expression	[12]
Neuroblast differentiation-associated protein AHNAK (AHNAK)	OT6KH1WG	AHNK_HUMAN	Decreases Expression	[12]
Zinc transporter ZIP6 (SLC39A6)	OTCYF466	S39A6_HUMAN	Decreases Expression	[12]
Importin subunit beta-1 (KPNB1)	OTBT2HFL	IMB1_HUMAN	Decreases Expression	[12]
Proteasome activator complex subunit 4 (PSME4)	OTDGF53O	PSME4_HUMAN	Decreases Expression	[12]
Condensin complex subunit 2 (NCAPH)	OTXOS97C	CND2_HUMAN	Decreases Expression	[12]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Decreases Expression	[12]
26S proteasome non-ATPase regulatory subunit 6 (PSMD6)	OTX59EGK	PSMD6_HUMAN	Decreases Expression	[12]
Elongin-B (ELOB)	OTZ3X84T	ELOB_HUMAN	Decreases Expression	[12]
Histone-binding protein RBBP7 (RBBP7)	OTLB56HX	RBBP7_HUMAN	Decreases Expression	[12]
Transcription initiation factor TFIID subunit 9 (TAF9)	OTCTH3C6	TAF9_HUMAN	Decreases Expression	[12]
Golgin subfamily A member 5 (GOLGA5)	OTG6HB6U	GOGA5_HUMAN	Decreases Expression	[12]
Transportin-1 (TNPO1)	OT7W2CM8	TNPO1_HUMAN	Decreases Expression	[12]
Dehydrodolichyl diphosphate synthase complex subunit NUS1 (NUS1)	OT4DQ82L	NGBR_HUMAN	Decreases Expression	[12]
UAP56-interacting factor (FYTTD1)	OTXXKQJR	UIF_HUMAN	Decreases Expression	[12]
Rac GTPase-activating protein 1 (RACGAP1)	OTQE8IEH	RGAP1_HUMAN	Decreases Expression	[12]
Protein ILRUN (ILRUN)	OTE8FHQD	ILRUN_HUMAN	Decreases Expression	[12]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2)	OTAQD3YV	ARNT2_HUMAN	Increases Expression	[12]
Nucleolar RNA helicase 2 (DDX21)	OTV73GMZ	DDX21_HUMAN	Decreases Expression	[12]
Very long chain fatty acid elongase 5 (ELOVL5)	OT375W1Z	ELOV5_HUMAN	Decreases Expression	[12]
Serine/threonine-protein kinase 26 (STK26)	OTW4QE0D	STK26_HUMAN	Decreases Expression	[12]
Cytochrome P450 1A1 (CYP1A1)	OTE4EFH8	CP1A1_HUMAN	Increases Expression	[22]
Serine/threonine-protein kinase Sgk1 (SGK1)	OT301T1U	SGK1_HUMAN	Decreases Expression	[13]
Prostaglandin E synthase (PTGES)	OTB7YQFU	PTGES_HUMAN	Decreases Expression	[13]
E3 ubiquitin-protein ligase SIAH2 (SIAH2)	OTKED2XN	SIAH2_HUMAN	Decreases Expression	[13]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Decreases Expression	[13]
Tyrosine-protein kinase JAK2 (JAK2)	OTBIDOOR	JAK2_HUMAN	Decreases Expression	[13]
monooxygenase MICAL2 (MICAL2)	OT04OQQJ	MICA2_HUMAN	Decreases Expression	[13]
Transcription factor AP-2-alpha (TFAP2A)	OTMYT3NK	AP2A_HUMAN	Increases Expression	[13]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET)	OTLU040A	RET_HUMAN	Decreases Expression	[13]
Monoacylglycerol lipase ABHD2 (ABHD2)	OTCRUOCS	ABHD2_HUMAN	Decreases Expression	[13]
Transcriptional activator Myb (MYB)	OTJH64IV	MYB_HUMAN	Decreases Expression	[13]
Myb-related protein A (MYBL1)	OTBJMC2P	MYBA_HUMAN	Decreases Expression	[13]
Tissue factor pathway inhibitor (TFPI)	OTA0FX16	TFPI1_HUMAN	Increases Expression	[13]
Delta-aminolevulinic acid dehydratase (ALAD)	OTHM9GSH	HEM2_HUMAN	Increases Expression	[13]
CD44 antigen (CD44)	OT9TTJ41	CD44_HUMAN	Decreases Expression	[13]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Decreases Expression	[13]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Increases Expression	[13]
Single-stranded DNA-binding protein 2 (SSBP2)	OTYG1G80	SSBP2_HUMAN	Increases Expression	[13]
Large neutral amino acids transporter small subunit 1 (SLC7A5)	OT2WPVXD	LAT1_HUMAN	Decreases Expression	[13]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Increases Expression	[13]
Urokinase plasminogen activator surface receptor (PLAUR)	OTIRKKEQ	UPAR_HUMAN	Decreases Expression	[13]
Early growth response protein 3 (EGR3)	OTGPJIRA	EGR3_HUMAN	Decreases Expression	[13]
Forkhead box protein C1 (FOXC1)	OTOWZGYO	FOXC1_HUMAN	Decreases Expression	[13]
Cyclin-G2 (CCNG2)	OTII38K2	CCNG2_HUMAN	Increases Expression	[13]
Kynureninase (KYNU)	OTINL2RE	KYNU_HUMAN	Increases Expression	[13]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1)	OTGFK4MH	NHRF3_HUMAN	Decreases Expression	[13]
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3)	OTXGJ8N1	P55G_HUMAN	Increases Expression	[13]
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2)	OTMDVWPS	DYRK2_HUMAN	Increases Expression	[13]
Transcription factor AP-2 gamma (TFAP2C)	OTUDIW05	AP2C_HUMAN	Decreases Expression	[13]
Serine/threonine-protein kinase Sgk3 (SGK3)	OTQ6QO99	SGK3_HUMAN	Decreases Expression	[13]
Inactive rhomboid protein 1 (RHBDF1)	OTCQ7UDS	RHDF1_HUMAN	Increases Expression	[13]
Calmin (CLMN)	OT7U5J3T	CLMN_HUMAN	Increases Expression	[13]
DNA endonuclease RBBP8 (RBBP8)	OTRHJ3GI	CTIP_HUMAN	Decreases Expression	[13]
Noelin (OLFM1)	OTOYPEWW	NOE1_HUMAN	Decreases Expression	[13]
Pleckstrin homology domain-containing family F member 2 (PLEKHF2)	OTBGDG8C	PKHF2_HUMAN	Increases Expression	[13]
Spermine oxidase (SMOX)	OT11E62Y	SMOX_HUMAN	Decreases Expression	[13]
Nicotinamide riboside kinase 1 (NMRK1)	OT0STQLV	NRK1_HUMAN	Decreases Expression	[13]
Rap guanine nucleotide exchange factor-like 1 (RAPGEFL1)	OTYKE9ZM	RPGFL_HUMAN	Decreases Expression	[13]
RNA 3'-terminal phosphate cyclase-like protein (RCL1)	OT7O00YX	RCL1_HUMAN	Decreases Expression	[13]
Cytochrome P450 1B1 (CYP1B1)	OTYXFLSD	CP1B1_HUMAN	Increases Expression	[23]
Extended synaptotagmin-3 (ESYT3)	OTG5H3YF	ESYT3_HUMAN	Increases Methylation	[14]
FERM domain-containing protein 3 (FRMD3)	OT0CD2GG	FRMD3_HUMAN	Increases Methylation	[14]
Dystrotelin (DYTN)	OTC5QZ6R	DYTN_HUMAN	Increases Methylation	[14]
Coiled-coil domain-containing protein 144A (CCDC144A)	OTN9UZHR	C144A_HUMAN	Decreases Methylation	[14]
Transmembrane protein 89 (TMEM89)	OTZLX09R	TMM89_HUMAN	Increases Methylation	[14]
Delphilin (GRID2IP)	OTNDNC0W	GRD2I_HUMAN	Increases Methylation	[14]
Paralemmin-3 (PALM3)	OTB83R61	PALM3_HUMAN	Increases Methylation	[14]
Rho GTPase-activating protein 42 (ARHGAP42)	OTIDSJMK	RHG42_HUMAN	Increases Methylation	[14]
Ciliary microtubule inner protein 2C (CIMIP2C)	OTKXQKQ4	CMI2C_HUMAN	Increases Methylation	[14]
Fidgetin-like protein 2 (FIGNL2)	OT0GD7S6	FIGL2_HUMAN	Increases Methylation	[14]
Dorsal root ganglia homeobox protein (DRGX)	OTDLEGNE	DRGX_HUMAN	Increases Methylation	[14]
Uncharacterized protein C12orf71 (C12ORF71)	OTUFA24U	CL071_HUMAN	Increases Methylation	[14]
Uncharacterized protein C16orf90 (C16ORF90)	OTAYN87M	CP090_HUMAN	Increases Methylation	[14]
Isthmin-1 (ISM1)	OTZTK2TV	ISM1_HUMAN	Increases Methylation	[14]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L)	OT7QO47I	RBG10_HUMAN	Increases Methylation	[14]
Uncharacterized protein C19orf84 (C19ORF84)	OT4MVCU6	CS084_HUMAN	Increases Methylation	[14]
Golgi-associated olfactory signaling regulator (GFY)	OTM64CSN	GFY_HUMAN	Increases Methylation	[14]
ATP-dependent RNA helicase DDX39A (DDX39A)	OT0Z6E1K	DX39A_HUMAN	Increases Methylation	[14]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7)	OT7C68YV	BACH_HUMAN	Increases Methylation	[14]
Synaptosomal-associated protein 23 (SNAP23)	OTY2MYBX	SNP23_HUMAN	Increases Methylation	[14]
Splicing regulator ARVCF (ARVCF)	OT78DKOU	ARVC_HUMAN	Increases Methylation	[14]
AP-3 complex subunit beta-1 (AP3B1)	OTYTIH5Q	AP3B1_HUMAN	Decreases Expression	[16]
E3 ubiquitin-protein ligase RNF103 (RNF103)	OT9DOB4H	RN103_HUMAN	Increases Methylation	[14]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Expression	[16]
Importin-5 (IPO5)	OTAK40ED	IPO5_HUMAN	Increases Methylation	[14]
Histone deacetylase complex subunit SAP18 (SAP18)	OTJAZWOL	SAP18_HUMAN	Increases Methylation	[14]
Nuclear receptor subfamily 5 group A member 2 (NR5A2)	OTXAUJAS	NR5A2_HUMAN	Increases Expression	[16]
Serine/threonine-protein kinase 25 (STK25)	OT4YPNTF	STK25_HUMAN	Increases Methylation	[14]
Receptor-binding cancer antigen expressed on SiSo cells (EBAG9)	OTTQLQCP	RCAS1_HUMAN	Decreases Expression	[16]
Pro-neuregulin-2, membrane-bound isoform (NRG2)	OTMDE844	NRG2_HUMAN	Increases Methylation	[14]
Homeobox protein cut-like 2 (CUX2)	OTDJTQAJ	CUX2_HUMAN	Increases Methylation	[14]
Suppressor of cytokine signaling 3 (SOCS3)	OTY183WJ	SOCS3_HUMAN	Decreases Expression	[16]
Olfactory receptor 7A17 (OR7A17)	OTFYB5NE	OR7AH_HUMAN	Increases Methylation	[14]
Telomerase reverse transcriptase (TERT)	OT085VVA	TERT_HUMAN	Decreases Expression	[24]
Guanine nucleotide-binding protein subunit beta-5 (GNB5)	OT3ZSAXH	GNB5_HUMAN	Increases Methylation	[14]
Kinetochore protein NDC80 homolog (NDC80)	OTS7D306	NDC80_HUMAN	Decreases Expression	[15]
Neuropilin-1 (NRP1)	OTCGULYV	NRP1_HUMAN	Decreases Expression	[16]
Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2)	OT67DAGF	RGRF2_HUMAN	Decreases Methylation	[14]
Protocadherin-17 (PCDH17)	OTRK0M05	PCD17_HUMAN	Decreases Methylation	[14]
Regulator of G-protein signaling 12 (RGS12)	OTNCIQTH	RGS12_HUMAN	Increases Methylation	[14]
Microtubule-associated serine/threonine-protein kinase 4 (MAST4)	OT3LOE2J	MAST4_HUMAN	Increases Methylation	[14]
Guanine nucleotide exchange factor DBS (MCF2L)	OTEURA8N	MCF2L_HUMAN	Affects Methylation	[14]
Ephrin type-B receptor 6 (EPHB6)	OTKNN6GC	EPHB6_HUMAN	Increases Methylation	[14]
Laminin subunit alpha-5 (LAMA5)	OTIIXE4M	LAMA5_HUMAN	Increases Methylation	[14]
Ataxin-7 (ATXN7)	OTL3YF1H	ATX7_HUMAN	Decreases Methylation	[14]
Tumor protein p73 (TP73)	OT0LUO47	P73_HUMAN	Increases Methylation	[14]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Decreases Expression	[15]
Trinucleotide repeat-containing gene 18 protein (TNRC18)	OTREUWWG	TNC18_HUMAN	Decreases Methylation	[14]
Tapasin (TAPBP)	OTL81AVZ	TPSN_HUMAN	Increases Methylation	[14]
Rho guanine nucleotide exchange factor 9 (ARHGEF9)	OTB1FLIW	ARHG9_HUMAN	Increases Methylation	[14]
ERI1 exoribonuclease 3 (ERI3)	OT0HIU61	ERI3_HUMAN	Increases Methylation	[14]
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1)	OTDTF5BU	SUV91_HUMAN	Increases Methylation	[14]
Forkhead box protein O3 (FOXO3)	OTHXQG4P	FOXO3_HUMAN	Affects Localization	[25]
Protein sprouty homolog 2 (SPRY2)	OTH0CRCZ	SPY2_HUMAN	Affects Methylation	[14]
Pleiotropic regulator 1 (PLRG1)	OTIVZ5LL	PLRG1_HUMAN	Increases Methylation	[14]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[16]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)	OT80DZMT	BUB1_HUMAN	Decreases Expression	[15]
Sialic acid-binding Ig-like lectin 6 (SIGLEC6)	OTO4F5C9	SIGL6_HUMAN	Increases Methylation	[14]
Tolloid-like protein 1 (TLL1)	OTK9NM7G	TLL1_HUMAN	Decreases Methylation	[14]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L)	OTJKOMXE	BNI3L_HUMAN	Increases Methylation	[14]
NUAK family SNF1-like kinase 1 (NUAK1)	OTLLHJJQ	NUAK1_HUMAN	Increases Methylation	[14]
Phospholipid-transporting ATPase VA (ATP10A)	OTYF5A7X	AT10A_HUMAN	Decreases Methylation	[14]
Protein ENTREP2 (ENTREP2)	OTEUHFKS	EREP2_HUMAN	Increases Methylation	[14]
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1C)	OT3LPG1R	PI51C_HUMAN	Decreases Methylation	[14]
Gasdermin-E (GSDME)	OT1ZWY32	GSDME_HUMAN	Increases Methylation	[14]
Docking protein 2 (DOK2)	OTIJ38UF	DOK2_HUMAN	Increases Methylation	[14]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)	OT8KME51	BUB1B_HUMAN	Decreases Expression	[15]
Musculin (MSC)	OTBRPZL5	MUSC_HUMAN	Increases Methylation	[14]
Catenin delta-1 (CTNND1)	OTUMPSHR	CTND1_HUMAN	Decreases Methylation	[14]
Low-density lipoprotein receptor-related protein 3 (LRP3)	OTXMLT8C	LRP3_HUMAN	Increases Methylation	[14]
Protein CBFA2T3 (CBFA2T3)	OTOJ10S1	MTG16_HUMAN	Increases Methylation	[14]
Multiple epidermal growth factor-like domains protein 6 (MEGF6)	OTEUYTP1	MEGF6_HUMAN	Increases Methylation	[14]
Rho-associated protein kinase 2 (ROCK2)	OTVYN14T	ROCK2_HUMAN	Increases Methylation	[14]
TSC22 domain family protein 2 (TSC22D2)	OTFXF349	T22D2_HUMAN	Increases Methylation	[14]
Cadherin-16 (CDH16)	OTR0GE9G	CAD16_HUMAN	Increases Methylation	[14]
Nuclear receptor corepressor 1 (NCOR1)	OT04XNOU	NCOR1_HUMAN	Increases Expression	[16]
Alpha-tectorin (TECTA)	OT5E0NE2	TECTA_HUMAN	Decreases Methylation	[14]
Nuclear receptor subfamily 1 group I member 2 (NR1I2)	OTC5U0N5	NR1I2_HUMAN	Increases Activity	[26]
PC4 and SFRS1-interacting protein (PSIP1)	OT4YAFUS	PSIP1_HUMAN	Increases Methylation	[14]
Carbonic anhydrase-related protein 11 (CA11)	OT8RX3AJ	CAH11_HUMAN	Decreases Methylation	[14]
Disabled homolog 1 (DAB1)	OTPL9MA3	DAB1_HUMAN	Increases Methylation	[14]
Serpin B7 (SERPINB7)	OTZ95LR2	SPB7_HUMAN	Increases Methylation	[14]
Cell cycle checkpoint protein RAD17 (RAD17)	OT1I93DT	RAD17_HUMAN	Increases Methylation	[14]
CCN family member 5 (CCN5)	OTADU8JJ	CCN5_HUMAN	Increases Expression	[16]
Regulator of G-protein signaling 20 (RGS20)	OT6CGYHW	RGS20_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase 17B (STK17B)	OT4NYNO8	ST17B_HUMAN	Increases Methylation	[14]
Slit homolog 2 protein (SLIT2)	OTLS2RJ4	SLIT2_HUMAN	Increases Methylation	[14]
Dendrin (DDN)	OTM52ZF5	DEND_HUMAN	Increases Methylation	[14]
Protein FAM13A (FAM13A)	OTZ6GN0Q	FA13A_HUMAN	Decreases Methylation	[14]
G2/mitotic-specific cyclin-B2 (CCNB2)	OTIEXTDK	CCNB2_HUMAN	Decreases Expression	[15]
Serine protease 23 (PRSS23)	OT6DQAM1	PRS23_HUMAN	Increases Methylation	[14]
NADH dehydrogenase 1 beta subcomplex subunit 2, mitochondrial (NDUFB2)	OT4717TF	NDUB2_HUMAN	Increases Methylation	[14]
Potassium voltage-gated channel subfamily H member 1 (KCNH1)	OTZZXWER	KCNH1_HUMAN	Decreases Expression	[27]
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10)	OTBURQ3A	NDUAA_HUMAN	Decreases Methylation	[14]
CUGBP Elav-like family member 2 (CELF2)	OTLJJ4VT	CELF2_HUMAN	Increases Methylation	[14]
Homeobox protein SIX3 (SIX3)	OTP5E3VU	SIX3_HUMAN	Decreases Methylation	[14]
Transforming acidic coiled-coil-containing protein 2 (TACC2)	OTW4M7HI	TACC2_HUMAN	Increases Methylation	[14]
Supervillin (SVIL)	OTWQQ1WK	SVIL_HUMAN	Increases Methylation	[14]
Sodium-dependent phosphate transport protein 2B (SLC34A2)	OTLFMBB0	NPT2B_HUMAN	Increases Methylation	[14]
Adhesion G protein-coupled receptor L2 (ADGRL2)	OTCXD2YR	AGRL2_HUMAN	Decreases Methylation	[14]
Solute carrier family 2, facilitated glucose transporter member 10 (SLC2A10)	OTL32QH7	GTR10_HUMAN	Decreases Methylation	[14]
Apoptosis-inducing factor 1, mitochondrial (AIFM1)	OTKPWB7Q	AIFM1_HUMAN	Decreases Methylation	[14]
Zinc finger protein SNAI1 (SNAI1)	OTDPYAMC	SNAI1_HUMAN	Increases Expression	[16]
Phosphatidylserine lipase ABHD16A (ABHD16A)	OTDS9K1Z	ABHGA_HUMAN	Increases Methylation	[14]
Uncharacterized protein C6orf47 (C6ORF47)	OTMKBNDD	CF047_HUMAN	Increases Methylation	[14]
One cut domain family member 2 (ONECUT2)	OTHUE5YY	ONEC2_HUMAN	Increases Methylation	[14]
Cholesterol 25-hydroxylase (CH25H)	OT9S2BSW	CH25H_HUMAN	Increases Methylation	[14]
Securin (PTTG1)	OTIMYS4W	PTTG1_HUMAN	Decreases Expression	[28]
G1/S-specific cyclin-E2 (CCNE2)	OTBBUKQQ	CCNE2_HUMAN	Decreases Expression	[15]
Aspartate aminotransferase, mitochondrial (GOT2)	OT6XBWN0	AATM_HUMAN	Increases Methylation	[14]
Adenosine deaminase (ADA)	OTOX2872	ADA_HUMAN	Decreases Methylation	[14]
Complement C3 (C3)	OTCH5GS0	CO3_HUMAN	Decreases Expression	[16]
Pro-epidermal growth factor (EGF)	OTANRJ0L	EGF_HUMAN	Affects Activity	[29]
Protransforming growth factor alpha (TGFA)	OTPD1LL9	TGFA_HUMAN	Increases Expression	[16]
Transforming growth factor beta-1 proprotein (TGFB1)	OTV5XHVH	TGFB1_HUMAN	Increases Expression	[30]
Prolactin (PRL)	OTWFQGX7	PRL_HUMAN	Decreases Secretion	[31]
Interleukin-1 beta (IL1B)	OT0DWXXB	IL1B_HUMAN	Increases Expression	[32]
Complement component C9 (C9)	OT7I5FDX	CO9_HUMAN	Increases Methylation	[14]
Lactotransferrin (LTF)	OT8JWCZ0	TRFL_HUMAN	Increases Expression	[16]
Estrogen receptor (ESR1)	OTKLU61J	ESR1_HUMAN	Decreases Expression	[33]
Glucocorticoid receptor (NR3C1)	OTCI2YDI	GCR_HUMAN	Increases Expression	[16]
Trefoil factor 1 (TFF1)	OTCYQH4F	TFF1_HUMAN	Decreases Expression	[34]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Decreases Expression	[35]
Non-histone chromosomal protein HMG-14 (HMGN1)	OTSMGH99	HMGN1_HUMAN	Decreases Methylation	[14]
Plasminogen activator inhibitor 2 (SERPINB2)	OT72QLZB	PAI2_HUMAN	Increases Expression	[32]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Increases Expression	[32]
Keratin, type I cytoskeletal 18 (KRT18)	OTVLQFIP	K1C18_HUMAN	Increases Methylation	[14]
Tyrosine-protein kinase Lck (LCK)	OT883FG9	LCK_HUMAN	Increases Methylation	[14]
Retinoblastoma-associated protein (RB1)	OTQJUJMZ	RB_HUMAN	Decreases Phosphorylation	[36]
Progesterone receptor (PGR)	OT0FZ3QE	PRGR_HUMAN	Decreases Expression	[37]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Decreases Expression	[15]
ATP synthase subunit beta, mitochondrial (ATP5F1B)	OTLFZUQK	ATPB_HUMAN	Increases Expression	[38]
Complement C2 (C2)	OTHMF4YM	CO2_HUMAN	Increases Methylation	[14]
Lipoprotein lipase (LPL)	OTTW0267	LIPL_HUMAN	Decreases Expression	[16]
Neurofilament medium polypeptide (NEFM)	OT8VCBNF	NFM_HUMAN	Increases Methylation	[14]
Thyroid peroxidase (TPO)	OTJJLL20	PERT_HUMAN	Increases Methylation	[14]
Prostate-specific antigen (KLK3)	OTFGSBFJ	KLK3_HUMAN	Decreases Expression	[16]
Cathepsin D (CTSD)	OTQZ36F3	CATD_HUMAN	Decreases Expression	[34]
Heat shock protein HSP 90-alpha (HSP90AA1)	OTLG1WPK	HS90A_HUMAN	Increases Expression	[16]
Tyrosine-protein kinase Lyn (LYN)	OTP686K2	LYN_HUMAN	Increases Methylation	[14]
Thrombospondin-1 (THBS1)	OT0ECWK3	TSP1_HUMAN	Increases Expression	[16]
Insulin-like growth factor 1 receptor (IGF1R)	OTXJIF13	IGF1R_HUMAN	Increases Phosphorylation	[39]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Increases Expression	[40]
Insulin-like growth factor-binding protein 1 (IGFBP1)	OT6UQV2K	IBP1_HUMAN	Increases Expression	[16]
Galectin-1 (LGALS1)	OT8LDFWR	LEG1_HUMAN	Increases Expression	[16]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Decreases Expression	[32]
Granulocyte colony-stimulating factor (CSF3)	OT9GC6TP	CSF3_HUMAN	Decreases Expression	[32]
Histone H2A.Z (H2AZ1)	OT3KJJNQ	H2AZ_HUMAN	Decreases Expression	[41]
Protein RD3-like (RD3L)	OTLV3BU0	RD3L_HUMAN	Increases Methylation	[14]
Granzyme B (GZMB)	OTPPVIRS	GRAB_HUMAN	Decreases Expression	[30]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Increases Expression	[32]
Lysosomal alpha-glucosidase (GAA)	OT03PU29	LYAG_HUMAN	Increases Methylation	[14]
Androgen receptor (AR)	OTUBKAZZ	ANDR_HUMAN	Decreases Expression	[37]
Retinoic acid receptor alpha (RARA)	OT192V9V	RARA_HUMAN	Decreases Expression	[16]
Osteopontin (SPP1)	OTJGC23Y	OSTP_HUMAN	Increases Expression	[16]
Nuclear receptor subfamily 2 group F member 6 (NR2F6)	OTNVO2B6	NR2F6_HUMAN	Increases Expression	[16]
Transforming growth factor beta-3 proprotein (TGFB3)	OT2LOUQ1	TGFB3_HUMAN	Decreases Expression	[16]
Microtubule-associated protein tau (MAPT)	OTMTP2Z7	TAU_HUMAN	Decreases Expression	[42]
Mast/stem cell growth factor receptor Kit (KIT)	OTHUY3VZ	KIT_HUMAN	Increases Methylation	[14]
Ras-related protein Ral-A (RALA)	OT734R7X	RALA_HUMAN	Increases Expression	[16]
Spectrin beta chain, erythrocytic (SPTB)	OT1Q9ABM	SPTB1_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase pim-1 (PIM1)	OTWEKXTU	PIM1_HUMAN	Increases Expression	[32]
Glucose-6-phosphate 1-dehydrogenase (G6PD)	OT300SMK	G6PD_HUMAN	Increases Expression	[16]
Steroid hormone receptor ERR1 (ESRRA)	OTTDTUSP	ERR1_HUMAN	Increases Expression	[38]
Aromatase (CYP19A1)	OTZ6XF74	CP19A_HUMAN	Increases Expression	[16]
Dystrophin (DMD)	OTD21T5J	DMD_HUMAN	Decreases Methylation	[14]
Collagen alpha-2(VI) chain (COL6A2)	OTQC6PPO	CO6A2_HUMAN	Increases Methylation	[14]
Creatine kinase B-type (CKB)	OTUCKOTT	KCRB_HUMAN	Increases Expression	[16]
Bone morphogenetic protein 4 (BMP4)	OTPZMDFH	BMP4_HUMAN	Increases Expression	[16]
Nuclear receptor subfamily 2 group C member 1 (NR2C1)	OTJEL7WT	NR2C1_HUMAN	Increases Methylation	[14]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30)	OT9DERT1	GILT_HUMAN	Decreases Methylation	[14]
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Increases Expression	[16]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1)	OTNAZVKB	3BHS1_HUMAN	Increases Methylation	[14]
Perforin-1 (PRF1)	OTFVXD7H	PERF_HUMAN	Decreases Expression	[30]
Interleukin-1 receptor type 1 (IL1R1)	OTTU8959	IL1R1_HUMAN	Increases Methylation	[14]
Matrix metalloproteinase-9 (MMP9)	OTB2QDAV	MMP9_HUMAN	Increases Expression	[16]
Junction plakoglobin (JUP)	OTUH7VMO	PLAK_HUMAN	Increases Methylation	[14]
Nucleoside diphosphate kinase A (NME1)	OT0NELQ1	NDKA_HUMAN	Decreases Expression	[15]
Transcription factor 4 (TCF4)	OTB9ASTK	ITF2_HUMAN	Increases Methylation	[14]
Platelet-derived growth factor receptor alpha (PDGFRA)	OTDJXUCN	PGFRA_HUMAN	Decreases Methylation	[14]
Carboxypeptidase E (CPE)	OTXNTV79	CBPE_HUMAN	Increases Methylation	[14]
Transcription factor JunB (JUNB)	OTG2JXV5	JUNB_HUMAN	Increases Expression	[16]
Gap junction alpha-1 protein (GJA1)	OTT94MKL	CXA1_HUMAN	Decreases Expression	[43]
Creatine kinase S-type, mitochondrial (CKMT2)	OT1KNPI1	KCRS_HUMAN	Increases Methylation	[14]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Increases Methylation	[14]
Bone morphogenetic protein 7 (BMP7)	OTYATP2K	BMP7_HUMAN	Increases Expression	[16]
Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1)	OTSXJGQF	ITIH1_HUMAN	Increases Methylation	[14]
C-X-C motif chemokine 3 (CXCL3)	OTSL94KH	CXCL3_HUMAN	Increases Expression	[32]
Follistatin (FST)	OTRIVK9Y	FST_HUMAN	Increases Expression	[32]
Gastricsin (PGC)	OTQRITKI	PEPC_HUMAN	Increases Methylation	[14]
B-cell receptor CD22 (CD22)	OTXDJR9T	CD22_HUMAN	Increases Methylation	[14]
T-cell surface glycoprotein CD3 zeta chain (CD247)	OT45FGUX	CD3Z_HUMAN	Increases Methylation	[14]
Cytoplasmic aconitate hydratase (ACO1)	OT2VUR7L	ACOHC_HUMAN	Increases Methylation	[14]
Receptor tyrosine-protein kinase erbB-3 (ERBB3)	OTRSST0A	ERBB3_HUMAN	Decreases Expression	[16]
Catechol O-methyltransferase (COMT)	OTPWKTQG	COMT_HUMAN	Increases Expression	[16]
Tenascin-X (TNXB)	OTVBWAV5	TENX_HUMAN	Increases Methylation	[14]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Increases Methylation	[14]
Transcription elongation factor A protein 1 (TCEA1)	OTBFO594	TCEA1_HUMAN	Decreases Methylation	[14]
Cerebellin-1 (CBLN1)	OTIXFRAG	CBLN1_HUMAN	Increases Methylation	[14]
Brain-derived neurotrophic factor (BDNF)	OTLGH7EW	BDNF_HUMAN	Increases Expression	[16]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Decreases Expression	[33]
Insulin-like growth factor-binding protein 5 (IGFBP5)	OTRE5V0C	IBP5_HUMAN	Increases Expression	[16]
G1/S-specific cyclin-E1 (CCNE1)	OTLD7UID	CCNE1_HUMAN	Decreases Expression	[44]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Increases Expression	[44]
Endothelin-1 receptor (EDNRA)	OTK9T5O3	EDNRA_HUMAN	Increases Methylation	[14]
Atypical chemokine receptor 3 (ACKR3)	OTA6GA4F	ACKR3_HUMAN	Decreases Methylation	[14]
NF-kappa-B inhibitor alpha (NFKBIA)	OTFT924M	IKBA_HUMAN	Decreases Expression	[32]
Integrin beta-7 (ITGB7)	OT33UUKU	ITB7_HUMAN	Increases Methylation	[14]
DNA cytosine-5)-methyltransferase 1 (DNMT1)	OTM2DGTK	DNMT1_HUMAN	Decreases Expression	[15]
NKG2-C type II integral membrane protein (KLRC2)	OTT4N86S	NKG2C_HUMAN	Increases Methylation	[14]
Beta-crystallin B3 (CRYBB3)	OTTGTQIQ	CRBB3_HUMAN	Decreases Methylation	[14]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Increases Phosphorylation	[45]
Proteasome subunit beta type-8 (PSMB8)	OTW5XGMF	PSB8_HUMAN	Increases Methylation	[14]
Choline O-acetyltransferase (CHAT)	OTEJWQ45	CLAT_HUMAN	Increases Methylation	[14]
Gamma-aminobutyric acid receptor subunit rho-2 (GABRR2)	OTLDLU1S	GBRR2_HUMAN	Increases Methylation	[14]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Increases Phosphorylation	[45]
CCN family member 2 (CCN2)	OTC39NSU	CCN2_HUMAN	Increases Expression	[16]
Lysine-specific demethylase 5A (KDM5A)	OTLYFX8A	KDM5A_HUMAN	Increases Methylation	[14]
Leukocyte tyrosine kinase receptor (LTK)	OT4GPX7K	LTK_HUMAN	Decreases Methylation	[14]
Transmembrane 4 L6 family member 1 (TM4SF1)	OTY0ECQN	T4S1_HUMAN	Increases Methylation	[14]
Adenosine receptor A1 (ADORA1)	OTI7X39E	AA1R_HUMAN	Decreases Expression	[16]
Fibroblast growth factor 9 (FGF9)	OT2SKDGM	FGF9_HUMAN	Decreases Expression	[46]
Sodium- and chloride-dependent taurine transporter (SLC6A6)	OT67U7G3	SC6A6_HUMAN	Increases Methylation	[14]
Gamma-aminobutyric acid receptor subunit alpha-5 (GABRA5)	OTBIKWQT	GBRA5_HUMAN	Decreases Methylation	[14]
DnaJ homolog subfamily A member 1 (DNAJA1)	OT38BZQQ	DNJA1_HUMAN	Increases Methylation	[14]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)	OTCMMMIZ	3HIDH_HUMAN	Increases Methylation	[14]
Neural cell adhesion molecule L1 (L1CAM)	OTNWAQ4Y	L1CAM_HUMAN	Increases Expression	[16]
CD70 antigen (CD70)	OTHB2AL1	CD70_HUMAN	Increases Methylation	[14]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)	OTB06ESI	ACSL1_HUMAN	Increases Methylation	[14]
Cytochrome P450 2C18 (CYP2C18)	OTY687L9	CP2CI_HUMAN	Increases Methylation	[14]
Protein S100-A5 (S100A5)	OTCGGL6K	S10A5_HUMAN	Increases Expression	[16]
Protein S100-A3 (S100A3)	OTVIZJ2R	S10A3_HUMAN	Increases Methylation	[14]
Dual specificity protein kinase TTK (TTK)	OTBY1Z5H	TTK_HUMAN	Decreases Expression	[15]
Prostaglandin G/H synthase 2 (PTGS2)	OT75U9M4	PGH2_HUMAN	Increases Expression	[16]
Nuclear receptor ROR-alpha (RORA)	OTGQT12P	RORA_HUMAN	Increases Methylation	[14]
Sodium channel protein type 1 subunit alpha (SCN1A)	OTJ9ZTYI	SCN1A_HUMAN	Increases Methylation	[14]
Hepatocyte nuclear factor 1-beta (HNF1B)	OTSYIC3T	HNF1B_HUMAN	Decreases Expression	[47]
Transcription factor SOX-6 (SOX6)	OTT0W0LE	SOX6_HUMAN	Increases Methylation	[14]
Aryl hydrocarbon receptor (AHR)	OTFE4EYE	AHR_HUMAN	Increases Expression	[16]
Receptor-type tyrosine-protein kinase FLT3 (FLT3)	OTMSRYMK	FLT3_HUMAN	Increases Methylation	[14]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Decreases Expression	[33]
Collagen alpha-1(XVIII) chain (COL18A1)	OTJFUH6O	COIA1_HUMAN	Increases Methylation	[14]
Pre-B-cell leukemia transcription factor 3 (PBX3)	OT8WMVM4	PBX3_HUMAN	Increases Methylation	[14]
Glutamate receptor 3 (GRIA3)	OT34CNBR	GRIA3_HUMAN	Decreases Methylation	[14]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB)	OTO8JQJA	PK3CB_HUMAN	Increases Methylation	[14]
Phosphatidylinositol 4-kinase alpha (PI4KA)	OT2L2G6C	PI4KA_HUMAN	Increases Methylation	[14]
Dipeptidyl aminopeptidase-like protein 6 (DPP6)	OTWW3H0K	DPP6_HUMAN	Decreases Methylation	[14]
Tyrosine-protein kinase Tec (TEC)	OTU6QJAJ	TEC_HUMAN	Increases Methylation	[14]
Condensin-2 complex subunit D3 (NCAPD3)	OTOZY2UL	CNDD3_HUMAN	Increases Methylation	[14]
Cathepsin O (CTSO)	OTFL6VRO	CATO_HUMAN	Increases Expression	[16]
Aldehyde dehydrogenase family 3 member B1 (ALDH3B1)	OT5NEUQE	AL3B1_HUMAN	Increases Methylation	[14]
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4)	OTDK74C0	TNR4_HUMAN	Decreases Methylation	[14]
Neuronal acetylcholine receptor subunit alpha-4 (CHRNA4)	OT1H0ZXC	ACHA4_HUMAN	Increases Methylation	[14]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[36]
5-hydroxytryptamine receptor 5A (HTR5A)	OTRKPCQV	5HT5A_HUMAN	Increases Methylation	[14]
Tumor necrosis factor ligand superfamily member 6 (FASLG)	OTZARCHH	TNFL6_HUMAN	Decreases Methylation	[14]
G protein-activated inward rectifier potassium channel 2 (KCNJ6)	OTDE1FT0	KCNJ6_HUMAN	Increases Methylation	[14]
Retinoic acid receptor RXR-gamma (RXRG)	OT254B09	RXRG_HUMAN	Decreases Methylation	[14]
Nuclear receptor-interacting protein 1 (NRIP1)	OTIZOJQV	NRIP1_HUMAN	Decreases Expression	[16]
Protein PRRC2A (PRRC2A)	OTBX6FM5	PRC2A_HUMAN	Increases Methylation	[14]
Protein farnesyltransferase subunit beta (CHURC1-FNTB)	OT34M7E3	FNTB_HUMAN	Increases Methylation	[14]
Protein phosphatase 1F (PPM1F)	OTU0MVR7	PPM1F_HUMAN	Increases Methylation	[14]
Casein kinase I isoform epsilon (CSNK1E)	OTF0UXX6	KC1E_HUMAN	Increases Methylation	[14]
CCAAT/enhancer-binding protein delta (CEBPD)	OTNBIPMY	CEBPD_HUMAN	Increases Methylation	[14]
Nuclear pore complex protein Nup153 (NUP153)	OTCAS0AR	NU153_HUMAN	Increases Methylation	[14]
Protein Tob1 (TOB1)	OTNW949D	TOB1_HUMAN	Increases Methylation	[14]
Lipopolysaccharide-responsive and beige-like anchor protein (LRBA)	OTOUZN9G	LRBA_HUMAN	Increases Methylation	[14]
Transcription activator BRG1 (SMARCA4)	OT68WOPQ	SMCA4_HUMAN	Decreases Expression	[35]
Nuclear receptor subfamily 0 group B member 1 (NR0B1)	OTC8P9GN	NR0B1_HUMAN	Increases Expression	[16]
Serine/threonine-protein kinase Nek2 (NEK2)	OT1H27HO	NEK2_HUMAN	Decreases Expression	[15]
Beta-chimaerin (CHN2)	OTSSDPWN	CHIO_HUMAN	Increases Methylation	[14]
Ephrin-A5 (EFNA5)	OTOH4DRR	EFNA5_HUMAN	Increases Expression	[16]
Stanniocalcin-1 (STC1)	OTGVVXYF	STC1_HUMAN	Decreases Methylation	[14]
Ataxin-1 (ATXN1)	OTQF0HNR	ATX1_HUMAN	Increases Methylation	[14]
Huntingtin-associated protein 1 (HAP1)	OT6SG0JQ	HAP1_HUMAN	Increases Methylation	[14]
Myomesin-2 (MYOM2)	OTD2UOXW	MYOM2_HUMAN	Increases Methylation	[14]
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5)	OT2H1KDK	PTN5_HUMAN	Increases Methylation	[14]
Protein AF-10 (MLLT10)	OTURMDV7	AF10_HUMAN	Increases Methylation	[14]
Adenosine kinase (ADK)	OTXR6VDI	ADK_HUMAN	Increases Methylation	[14]
Hepatocyte nuclear factor 3-alpha (FOXA1)	OTEBY0TD	FOXA1_HUMAN	Increases Expression	[16]
Galectin-4 (LGALS4)	OTKQCG0H	LEG4_HUMAN	Increases Methylation	[14]
Histone deacetylase 4 (HDAC4)	OTQNGD32	HDAC4_HUMAN	Increases Methylation	[14]
Claudin-17 (CLDN17)	OTQCEYBY	CLD17_HUMAN	Decreases Methylation	[14]
Breast cancer anti-estrogen resistance protein 1 (BCAR1)	OTKT2C2N	BCAR1_HUMAN	Increases Expression	[16]
Pro-neuregulin-3, membrane-bound isoform (NRG3)	OTIFZ5CT	NRG3_HUMAN	Increases Methylation	[14]
Claudin-2 (CLDN2)	OTRF3D6Y	CLD2_HUMAN	Decreases Methylation	[14]
Neurexin-1-beta (NRXN1)	OTJN1JQA	NRX1B_HUMAN	Decreases Methylation	[14]
CD81 antigen (CD81)	OTQFXNAZ	CD81_HUMAN	Increases Methylation	[14]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)	OTOWDUNT	PTEN_HUMAN	Increases Methylation	[14]
26S proteasome complex subunit SEM1 (SEM1)	OTASLBM1	SEM1_HUMAN	Decreases Methylation	[14]
Protein max (MAX)	OTKZ0YKM	MAX_HUMAN	Increases Methylation	[14]
Small ribosomal subunit protein eS7 (RPS7)	OTIK25WI	RS7_HUMAN	Increases Methylation	[14]
Small nuclear ribonucleoprotein G (SNRPG)	OTWX4XK1	RUXG_HUMAN	Increases Methylation	[14]
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L)	OTSSOMUP	RPAB5_HUMAN	Decreases Methylation	[14]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A)	OT9297OG	2ABA_HUMAN	Increases Methylation	[14]
Inward rectifier potassium channel 2 (KCNJ2)	OT2OQEZS	KCNJ2_HUMAN	Decreases Methylation	[14]
Tropomyosin alpha-4 chain (TPM4)	OTN4YLYR	TPM4_HUMAN	Increases Methylation	[14]
Actin, alpha skeletal muscle (ACTA1)	OTOVGLPG	ACTS_HUMAN	Increases Methylation	[14]
Reelin (RELN)	OTLKMW1O	RELN_HUMAN	Increases Methylation	[14]
C-C motif chemokine 20 (CCL20)	OTUCJY4N	CCL20_HUMAN	Increases Expression	[32]
Small ribosomal subunit protein uS9m (MRPS9)	OTD4XOHS	RT09_HUMAN	Decreases Methylation	[14]
Mothers against decapentaplegic homolog 3 (SMAD3)	OTNA96MR	SMAD3_HUMAN	Increases Methylation	[14]
Calcium-transporting ATPase type 2C member 1 (ATP2C1)	OTQN51T3	AT2C1_HUMAN	Affects Methylation	[14]
Phospholipid-transporting ATPase IH (ATP11A)	OT7M9ZDK	AT11A_HUMAN	Increases Methylation	[14]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Increases Expression	[38]
Cyclin-dependent kinase 6 (CDK6)	OTR95N0X	CDK6_HUMAN	Increases Expression	[35]
Transcription factor E2F1 (E2F1)	OTLKYBBC	E2F1_HUMAN	Decreases Expression	[44]
Runt-related transcription factor 1 (RUNX1)	OTU7J84H	RUNX1_HUMAN	Decreases Methylation	[14]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)	OTCO26FV	HMCS1_HUMAN	Increases Methylation	[14]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP)	OTFP7AA8	PFKAP_HUMAN	Increases Methylation	[14]
DNA-binding protein SATB1 (SATB1)	OTT7SUVW	SATB1_HUMAN	Decreases Methylation	[14]
Zinc finger protein basonuclin-1 (BNC1)	OTGJ5WUF	BNC1_HUMAN	Decreases Methylation	[14]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1)	OTEUYEW6	ROR1_HUMAN	Increases Methylation	[14]
2-oxoglutarate dehydrogenase complex component E1 (OGDH)	OTHGTQWF	ODO1_HUMAN	Increases Methylation	[14]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Increases Methylation	[14]
Dystonin (DST)	OTHZBM4X	DYST_HUMAN	Increases Methylation	[14]
Caveolin-1 (CAV1)	OTEZUR1L	CAV1_HUMAN	Decreases Expression	[16]
Trefoil factor 2 (TFF2)	OTRXB19X	TFF2_HUMAN	Decreases Expression	[48]
Early growth response protein 4 (EGR4)	OT4R3ECK	EGR4_HUMAN	Increases Methylation	[14]
Focal adhesion kinase 1 (PTK2)	OT3Q1JDY	FAK1_HUMAN	Increases Degradation	[45]
Homeobox protein engrailed-1 (EN1)	OT2DKIDK	HME1_HUMAN	Decreases Methylation	[14]
Recombining binding protein suppressor of hairless (RBPJ)	OTD7CUG0	SUH_HUMAN	Increases Methylation	[14]
DNA repair protein RAD51 homolog 1 (RAD51)	OTNVWGC1	RAD51_HUMAN	Decreases Expression	[15]
Collagen alpha-1(XVI) chain (COL16A1)	OTOWKUO2	COGA1_HUMAN	Increases Methylation	[14]
Trichohyalin (TCHH)	OT4J7EFT	TRHY_HUMAN	Decreases Methylation	[14]
Forkhead box protein M1 (FOXM1)	OT5887KR	FOXM1_HUMAN	Decreases Expression	[15]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D)	OT1RWFV0	PDE4D_HUMAN	Decreases Methylation	[14]
Transmembrane protein 62 (TMEM62)	OTJ4SPCM	TMM62_HUMAN	Increases Methylation	[14]
General transcription factor 3C polypeptide 1 (GTF3C1)	OT7JK0RG	TF3C1_HUMAN	Increases Methylation	[14]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1)	OTNYXOZO	KCMA1_HUMAN	Increases Methylation	[14]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1)	OT2LP7LJ	SNF5_HUMAN	Increases Expression	[35]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Decreases Expression	[15]
Follistatin-related protein 1 (FSTL1)	OT6KEZUD	FSTL1_HUMAN	Increases Methylation	[14]
Splicing factor, suppressor of white-apricot homolog (SFSWAP)	OT7H3ETA	SFSWA_HUMAN	Increases Methylation	[14]
Heat shock protein 75 kDa, mitochondrial (TRAP1)	OTNG0L8J	TRAP1_HUMAN	Increases Methylation	[14]
Ankyrin-3 (ANK3)	OTJ3IRBP	ANK3_HUMAN	Increases Methylation	[14]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2)	OTVZD4H6	BNIP2_HUMAN	Increases Methylation	[14]
Interleukin-24 (IL24)	OT4VUWH1	IL24_HUMAN	Increases Expression	[32]
Semaphorin-3B (SEMA3B)	OTCZCPMS	SEM3B_HUMAN	Increases Methylation	[14]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)	OTXNGZCG	MD2L1_HUMAN	Decreases Expression	[15]
Growth factor receptor-bound protein 10 (GRB10)	OTCKXGRC	GRB10_HUMAN	Increases Methylation	[14]
Metastasis-associated protein MTA1 (MTA1)	OTBHW3S9	MTA1_HUMAN	Decreases Expression	[16]
C-terminal-binding protein 1 (CTBP1)	OTVYH2DH	CTBP1_HUMAN	Decreases Expression	[16]
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)	OT70Z4II	ADAM9_HUMAN	Increases Methylation	[14]
snRNA-activating protein complex subunit 2 (SNAPC2)	OTN0EL6L	SNPC2_HUMAN	Increases Methylation	[14]
Baculoviral IAP repeat-containing protein 3 (BIRC3)	OT3E95KB	BIRC3_HUMAN	Increases Methylation	[14]
Phosphatidylinositol-binding clathrin assembly protein (PICALM)	OTQVRPMQ	PICAL_HUMAN	Increases Methylation	[14]
Mastermind-like domain-containing protein 1 (MAMLD1)	OT9EVMQY	MAMD1_HUMAN	Decreases Methylation	[14]
Solute carrier family 12 member 1 (SLC12A1)	OT6YSX0G	S12A1_HUMAN	Decreases Methylation	[14]
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)	OTPLXCDN	DYR1A_HUMAN	Decreases Methylation	[14]
Protein patched homolog 1 (PTCH1)	OTMG07H5	PTC1_HUMAN	Increases Expression	[16]
Nuclear receptor coactivator 4 (NCOA4)	OTRVU0UA	NCOA4_HUMAN	Increases Methylation	[14]
ADP-ribosylation factor-related protein 1 (ARFRP1)	OTP1OV78	ARFRP_HUMAN	Increases Methylation	[14]
Protein Shroom2 (SHROOM2)	OTZ2FJ7Q	SHRM2_HUMAN	Increases Methylation	[14]
Beta-1-syntrophin (SNTB1)	OTSRBECI	SNTB1_HUMAN	Decreases Methylation	[14]
Nuclear nucleic acid-binding protein C1D (C1D)	OTI9PMN1	C1D_HUMAN	Decreases Methylation	[14]
Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C)	OT6KFNMS	CAC1C_HUMAN	Increases Methylation	[14]
Nidogen-2 (NID2)	OTHC33FF	NID2_HUMAN	Increases Methylation	[14]
Protein FAM53B (FAM53B)	OTVD7OU6	FA53B_HUMAN	Decreases Methylation	[14]
Four and a half LIM domains protein 2 (FHL2)	OT0OAYWT	FHL2_HUMAN	Increases Methylation	[14]
Dihydropyrimidinase-related protein 3 (DPYSL3)	OTINJV20	DPYL3_HUMAN	Increases Methylation	[14]
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1)	OTD1KRKO	DYHC1_HUMAN	Increases Methylation	[14]
Elongin-A (ELOA)	OTOQTF5K	ELOA1_HUMAN	Increases Methylation	[14]
Filamin-C (FLNC)	OT3F8J6Y	FLNC_HUMAN	Decreases Methylation	[14]
Histone RNA hairpin-binding protein (SLBP)	OTVYYQRT	SLBP_HUMAN	Decreases Methylation	[14]
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2)	OTPHGZ19	ITPR2_HUMAN	Increases Methylation	[14]
Indian hedgehog protein (IHH)	OT1DWGXC	IHH_HUMAN	Decreases Methylation	[14]
Separin (ESPL1)	OTMGEVOK	ESPL1_HUMAN	Decreases Expression	[15]
Disco-interacting protein 2 homolog A (DIP2A)	OTXPTR8R	DIP2A_HUMAN	Decreases Methylation	[14]
Latent-transforming growth factor beta-binding protein 1 (LTBP1)	OTR7Q75L	LTBP1_HUMAN	Decreases Expression	[16]
LIM and SH3 domain protein 1 (LASP1)	OT2QIDCL	LASP1_HUMAN	Increases Methylation	[14]
Sodium/hydrogen exchanger 5 (SLC9A5)	OTM70CXN	SL9A5_HUMAN	Decreases Methylation	[14]
Protein disulfide-isomerase A6 (PDIA6)	OT8YBR17	PDIA6_HUMAN	Increases Methylation	[14]
Inactive phospholipase C-like protein 1 (PLCL1)	OTJL2C79	PLCL1_HUMAN	Decreases Methylation	[14]
Cyclin-dependent kinase 10 (CDK10)	OTKP7TTR	CDK10_HUMAN	Increases Methylation	[14]
Plectin (PLEC)	OTU4XDEG	PLEC_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase 38 (STK38)	OTKMYCYR	STK38_HUMAN	Increases Methylation	[14]
RalA-binding protein 1 (RALBP1)	OTBIGB1D	RBP1_HUMAN	Increases Methylation	[14]
Ribosomal protein S6 kinase alpha-2 (RPS6KA2)	OTIOYUSU	KS6A2_HUMAN	Decreases Methylation	[14]
Scaffold attachment factor B1 (SAFB)	OTGRV2LW	SAFB1_HUMAN	Increases Methylation	[14]
Nuclear receptor subfamily 0 group B member 2 (NR0B2)	OT7UVICX	NR0B2_HUMAN	Decreases Expression	[16]
Nuclear receptor coactivator 2 (NCOA2)	OTMQFPBB	NCOA2_HUMAN	Increases Expression	[16]
Olfactory receptor 1C1 (OR1C1)	OT9WTEX5	OR1C1_HUMAN	Decreases Methylation	[14]
Mediator of RNA polymerase II transcription subunit 1 (MED1)	OTOO24C4	MED1_HUMAN	Decreases Expression	[16]
ETS-related transcription factor Elf-2 (ELF2)	OTEI347F	ELF2_HUMAN	Increases Methylation	[14]
NGFI-A-binding protein 2 (NAB2)	OTG4BDF3	NAB2_HUMAN	Increases Expression	[16]
Nuclear receptor coactivator 1 (NCOA1)	OTLIUJQD	NCOA1_HUMAN	Increases Expression	[16]
Glutamate receptor ionotropic, kainate 4 (GRIK4)	OTL5EIPA	GRIK4_HUMAN	Decreases Methylation	[14]
NT-3 growth factor receptor (NTRK3)	OTII30MY	NTRK3_HUMAN	Increases Methylation	[14]
Meprin A subunit alpha (MEP1A)	OTY2Z48T	MEP1A_HUMAN	Increases Methylation	[14]
Receptor-type tyrosine-protein phosphatase O (PTPRO)	OTFLKWOY	PTPRO_HUMAN	Increases Methylation	[14]
Cysteine dioxygenase type 1 (CDO1)	OTLG1P77	CDO1_HUMAN	Decreases Methylation	[14]
Protein inscuteable homolog (INSC)	OTP16ERR	INSC_HUMAN	Increases Methylation	[14]
Inverted formin-2 (INF2)	OT8ZM13C	INF2_HUMAN	Increases Methylation	[14]
Transmembrane protein 266 (TMEM266)	OTM17VHD	TM266_HUMAN	Increases Methylation	[14]
ATP-binding cassette sub-family B member 5 (ABCB5)	OT8AKP1J	ABCB5_HUMAN	Increases Methylation	[14]
CST complex subunit CTC1 (CTC1)	OTRJY7QD	CTC1_HUMAN	Decreases Methylation	[14]
FH1/FH2 domain-containing protein 3 (FHOD3)	OT1WUBQX	FHOD3_HUMAN	Decreases Methylation	[14]
Carcinoembryonic antigen-related cell adhesion molecule 16 (CEACAM16)	OTUMUSY0	CEA16_HUMAN	Increases Methylation	[14]
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1)	OTN7XAUD	LRRF1_HUMAN	Decreases Methylation	[14]
Polycomb group RING finger protein 3 (PCGF3)	OTY7TPPZ	PCGF3_HUMAN	Increases Methylation	[14]
MAP7 domain-containing protein 1 (MAP7D1)	OTMGC8N9	MA7D1_HUMAN	Decreases Methylation	[14]
Mucin-like protein 3 (MUCL3)	OTGAD3I0	MUCL3_HUMAN	Increases Methylation	[14]
Cilia- and flagella-associated protein 100 (CFAP100)	OTHHFM2Z	CP100_HUMAN	Increases Methylation	[14]
Spermatogenesis-associated serine-rich protein 1 (SPATS1)	OTPUXCSA	SPAS1_HUMAN	Decreases Methylation	[14]
Cryptochrome-2 (CRY2)	OTERZ93T	CRY2_HUMAN	Increases Methylation	[14]
Ceramide kinase-like protein (CERKL)	OTG4YGBR	CERKL_HUMAN	Decreases Methylation	[14]
NAD kinase 2, mitochondrial (NADK2)	OT1I8GDE	NAKD2_HUMAN	Decreases Methylation	[14]
Glucoside xylosyltransferase 1 (GXYLT1)	OTI5MDYW	GXLT1_HUMAN	Increases Methylation	[14]
Protein GREB1 (GREB1)	OTU6ZA26	GREB1_HUMAN	Decreases Expression	[16]
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2)	OTB65N2I	PAN2_HUMAN	Increases Methylation	[14]
Acylglycerol kinase, mitochondrial (AGK)	OTJGWBYT	AGK_HUMAN	Increases Methylation	[14]
Fibulin-7 (FBLN7)	OT1XRDP6	FBLN7_HUMAN	Increases Methylation	[14]
FRAS1-related extracellular matrix protein 1 (FREM1)	OTMHRV87	FREM1_HUMAN	Increases Methylation	[14]
SH3 domain-containing protein 19 (SH3D19)	OTVU3VS2	SH319_HUMAN	Increases Methylation	[14]
Protein crumbs homolog 2 (CRB2)	OTG0L2CE	CRUM2_HUMAN	Increases Expression	[16]
NHL repeat-containing protein 3 (NHLRC3)	OTBI6YSN	NHLC3_HUMAN	Increases Methylation	[14]
Dedicator of cytokinesis protein 11 (DOCK11)	OTFSTN6A	DOC11_HUMAN	Increases Methylation	[14]
Protein FAM78A (FAM78A)	OTDZ36V8	FA78A_HUMAN	Decreases Methylation	[14]
EF-hand domain-containing protein 1 (EFHC1)	OTS9IBNE	EFHC1_HUMAN	Increases Methylation	[14]
Calcium homeostasis modulator protein 4 (CALHM4)	OTUDL2HG	CAHM4_HUMAN	Increases Methylation	[14]
Tubulin-specific chaperone cofactor E-like protein (TBCEL)	OT2PZLLL	TBCEL_HUMAN	Increases Methylation	[14]
Mucin-21 (MUC21)	OTQ8GP5L	MUC21_HUMAN	Increases Methylation	[14]
Uncharacterized protein C6orf132 (C6ORF132)	OTMH4S7O	CF132_HUMAN	Increases Methylation	[14]
Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1)	OT1N2182	CAMP1_HUMAN	Increases Methylation	[14]
Uncharacterized protein C1orf185 (C1ORF185)	OT32C5NW	CA185_HUMAN	Increases Methylation	[14]
Coiled-coil domain-containing protein 18 (CCDC18)	OT0S9DA2	CCD18_HUMAN	Decreases Methylation	[14]
Growth hormone-regulated TBC protein 1 (GRTP1)	OT8HORRZ	GRTP1_HUMAN	Increases Methylation	[14]
Protein sel-1 homolog 2 (SEL1L2)	OTSBDWIG	SE1L2_HUMAN	Increases Methylation	[14]
E3 ubiquitin-protein ligase RNF220 (RNF220)	OT2FIEXO	RN220_HUMAN	Increases Methylation	[14]
Forkhead box protein B2 (FOXB2)	OTJE3RRR	FOXB2_HUMAN	Increases Methylation	[14]
Armadillo repeat-containing protein 3 (ARMC3)	OTF6M9MM	ARMC3_HUMAN	Increases Methylation	[14]
Anoctamin-1 (ANO1)	OTSREUNI	ANO1_HUMAN	Increases Methylation	[14]
Meteorin-like protein (METRNL)	OTB0DDL0	METRL_HUMAN	Increases Methylation	[14]
DDB1- and CUL4-associated factor 15 (DCAF15)	OTWBXZ0E	DCA15_HUMAN	Increases Methylation	[14]
Autophagy-related protein 16-1 (ATG16L1)	OTEOYC5D	A16L1_HUMAN	Increases Methylation	[14]
Tensin-3 (TNS3)	OTPG2D8Z	TENS3_HUMAN	Increases Methylation	[14]
Coiled-coil domain-containing protein 102B (CCDC102B)	OTVDZVD0	C102B_HUMAN	Decreases Methylation	[14]
Cytosolic phospholipase A2 zeta (PLA2G4F)	OT8MUO5U	PA24F_HUMAN	Increases Methylation	[14]
NADH-cytochrome b5 reductase 2 (CYB5R2)	OTTLM7XN	NB5R2_HUMAN	Increases Methylation	[14]
Bridge-like lipid transfer protein family member 3A (BLTP3A)	OTRLMP17	BLT3A_HUMAN	Increases Methylation	[14]
Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2)	OTV5S1J2	CARL2_HUMAN	Increases Methylation	[14]
Fatty-acid amide hydrolase 2 (FAAH2)	OTS6LX01	FAAH2_HUMAN	Decreases Methylation	[14]
GRAM domain-containing protein 4 (GRAMD4)	OT1HXEPM	GRAM4_HUMAN	Decreases Methylation	[14]
Pleckstrin homology domain-containing family A member 7 (PLEKHA7)	OTNUMAZ0	PKHA7_HUMAN	Increases Methylation	[14]
Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GALNT3)	OT6BFB22	B4GN3_HUMAN	Decreases Methylation	[14]
Teneurin-4 (TENM4)	OT91K3FC	TEN4_HUMAN	Increases Methylation	[14]
SANT and BTB domain regulator of class switch recombination (SANBR)	OTY7ZODH	SANBR_HUMAN	Decreases Methylation	[14]
Homeobox-containing protein 1 (HMBOX1)	OTPKTBVI	HMBX1_HUMAN	Increases Methylation	[14]
TELO2-interacting protein 2 (TTI2)	OTU7TQCO	TTI2_HUMAN	Decreases Methylation	[14]
Phostensin (PPP1R18)	OT0JVGOZ	PPR18_HUMAN	Decreases Methylation	[14]
Phospholipase B1, membrane-associated (PLB1)	OTZ6TTYV	PLB1_HUMAN	Increases Methylation	[14]
Enhancer of mRNA-decapping protein 4 (EDC4)	OTBBNIUJ	EDC4_HUMAN	Increases Methylation	[14]
Uncharacterized protein C16orf46 (C16ORF46)	OT8FDG3A	CP046_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase Nek5 (NEK5)	OTHDXCYZ	NEK5_HUMAN	Increases Methylation	[14]
Neuroblastoma breakpoint family member 10 (NBPF10)	OTGOCELY	NBPFA_HUMAN	Affects Methylation	[14]
NIPA-like protein 3 (NIPAL3)	OTI858LL	NPAL3_HUMAN	Increases Methylation	[14]
Cytochrome b5 domain-containing protein 1 (CYB5D1)	OTSZWTPT	CB5D1_HUMAN	Increases Methylation	[14]
E3 ubiquitin-protein ligase RFWD3 (RFWD3)	OTDUULBQ	RFWD3_HUMAN	Decreases Methylation	[14]
tRNA methyltransferase 10 homolog B (TRMT10B)	OT3EJP6J	TM10B_HUMAN	Increases Methylation	[14]
Kv channel-interacting protein 4 (KCNIP4)	OTB1BS0X	KCIP4_HUMAN	Decreases Methylation	[14]
Docking protein 6 (DOK6)	OTX55OIF	DOK6_HUMAN	Affects Methylation	[14]
Solute carrier family 25 member 47 (SLC25A47)	OT5NGRWC	S2547_HUMAN	Increases Methylation	[14]
SCAN domain-containing protein 3 (SCAND3)	OTIIMBQL	SCND3_HUMAN	Decreases Methylation	[14]
Opsin-5 (OPN5)	OTCYGHDA	OPN5_HUMAN	Decreases Methylation	[14]
CREB-regulated transcription coactivator 3 (CRTC3)	OTVIGVUW	CRTC3_HUMAN	Increases Methylation	[14]
Golgi-associated kinase 1B (GASK1B)	OT2HPHEI	GAK1B_HUMAN	Decreases Methylation	[14]
Transmembrane and coiled-coil domain-containing protein 3 (TMCO3)	OTYW1KP2	TMCO3_HUMAN	Increases Methylation	[14]
Protein SNORC (SNORC)	OTY3IJK5	SNORC_HUMAN	Increases Methylation	[14]
Inactive serine protease PAMR1 (PAMR1)	OT83ZH5U	PAMR1_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase LMTK1 (AATK)	OTVHAX5N	LMTK1_HUMAN	Decreases Methylation	[14]
Metastasis-associated in colon cancer protein 1 (MACC1)	OTV3DLX0	MACC1_HUMAN	Decreases Methylation	[14]
Ferric-chelate reductase 1 (FRRS1)	OTQDEGEB	FRRS1_HUMAN	Increases Methylation	[14]
Neurobeachin-like protein 2 (NBEAL2)	OTMCAXWR	NBEL2_HUMAN	Increases Methylation	[14]
Transmembrane protein 182 (TMEM182)	OTVDIS2V	TM182_HUMAN	Increases Methylation	[14]
RING finger protein 207 (RNF207)	OT9AYVGV	RN207_HUMAN	Increases Methylation	[14]
Protein ITPRID1 (ITPRID1)	OT9MH0BX	ITPI1_HUMAN	Increases Methylation	[14]
Colorectal cancer-associated protein 1 (COLCA1)	OT8BP6UD	COLC1_HUMAN	Decreases Methylation	[14]
Protein shisa-6 (SHISA6)	OTWBCJ8O	SHSA6_HUMAN	Decreases Methylation	[14]
Major facilitator superfamily domain-containing protein 6 (MFSD6)	OTQ6KAV1	MFSD6_HUMAN	Increases Methylation	[14]
BEN domain-containing protein 4 (BEND4)	OT7Z1422	BEND4_HUMAN	Increases Methylation	[14]
Tumor protein p63-regulated gene 1 protein (TPRG1)	OTS48DQM	TPRG1_HUMAN	Increases Methylation	[14]
Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1)	OTMW1B47	BCAP_HUMAN	Increases Methylation	[14]
Coiled-coil domain-containing protein 149 (CCDC149)	OT7S7MU9	CC149_HUMAN	Decreases Methylation	[14]
Cytochrome P450 4V2 (CYP4V2)	OTQKNK0D	CP4V2_HUMAN	Decreases Methylation	[14]
MOB kinase activator 2 (MOB2)	OTMBE0NS	MOB2_HUMAN	Affects Methylation	[14]
RING finger protein 44 (RNF44)	OTGWL4U4	RNF44_HUMAN	Increases Methylation	[14]
DET1 homolog (DET1)	OTHYSDX3	DET1_HUMAN	Increases Methylation	[14]
MOB kinase activator 1B (MOB1B)	OTRE19ZS	MOB1B_HUMAN	Increases Methylation	[14]
Keratin, type I cytoskeletal 26 (KRT26)	OTLAXIN0	K1C26_HUMAN	Increases Methylation	[14]
CUB and sushi domain-containing protein 2 (CSMD2)	OT541Z3W	CSMD2_HUMAN	Increases Methylation	[14]
Protein lifeguard 1 (GRINA)	OTMC1O66	LFG1_HUMAN	Increases Methylation	[14]
Podocan (PODN)	OTV3P7P5	PODN_HUMAN	Increases Methylation	[14]
Protein sidekick-1 (SDK1)	OTX26906	SDK1_HUMAN	Increases Methylation	[14]
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B)	OT26DGM9	ANS1B_HUMAN	Increases Methylation	[14]
Transcription factor AP-2-delta (TFAP2D)	OT71O6YN	AP2D_HUMAN	Decreases Methylation	[14]
Pleckstrin homology domain-containing family H member 3 (PLEKHH3)	OTREOQBO	PKHH3_HUMAN	Increases Methylation	[14]
Cytokine-dependent hematopoietic cell linker (CLNK)	OTOWK51S	CLNK_HUMAN	Decreases Methylation	[14]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1)	OTKCR5XL	CK2N1_HUMAN	Increases Methylation	[14]
Uncharacterized protein C11orf96 (C11ORF96)	OTEQU0V7	CK096_HUMAN	Increases Methylation	[14]
Polypeptide N-acetylgalactosaminyltransferase 5 (GALNT5)	OTCV61V1	GALT5_HUMAN	Increases Methylation	[14]
Pleckstrin homology-like domain family B member 2 (PHLDB2)	OTDKMB2G	PHLB2_HUMAN	Increases Methylation	[14]
Protein hinderin (KIAA1328)	OT2RMGGB	K1328_HUMAN	Increases Methylation	[14]
TBC1 domain family member 1 (TBC1D1)	OTI9V7B0	TBCD1_HUMAN	Increases Methylation	[14]
Store-operated calcium entry regulator STIMATE (STIMATE)	OTEDLKEW	STIMA_HUMAN	Increases Methylation	[14]
Armadillo-like helical domain-containing protein 4 (ARMH4)	OT25GBJM	ARMD4_HUMAN	Increases Methylation	[14]
Protein polybromo-1 (PBRM1)	OT39WUR9	PB1_HUMAN	Decreases Methylation	[14]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2)	OTXDDKZS	MAGI2_HUMAN	Decreases Methylation	[14]
Reticulon-4 receptor-like 1 (RTN4RL1)	OTDKKOE7	R4RL1_HUMAN	Increases Methylation	[14]
Telomerase-binding protein EST1A (SMG6)	OTRCEJQL	EST1A_HUMAN	Increases Methylation	[14]
Leucine zipper protein 1 (LUZP1)	OTQV3VZM	LUZP1_HUMAN	Increases Methylation	[14]
Serine incorporator 5 (SERINC5)	OT3COPVF	SERC5_HUMAN	Increases Methylation	[14]
Myotubularin-related protein 13 (SBF2)	OTBB8NO8	MTMRD_HUMAN	Increases Methylation	[14]
Histone-arginine methyltransferase CARM1 (CARM1)	OT0IPRVR	CARM1_HUMAN	Increases Expression	[16]
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2)	OTHCYR6Y	ANKL2_HUMAN	Increases Methylation	[14]
Angiopoietin-related protein 5 (ANGPTL5)	OTC6AFVO	ANGL5_HUMAN	Increases Methylation	[14]
Cilium assembly protein DZIP1 (DZIP1)	OTBVPO66	DZIP1_HUMAN	Increases Methylation	[14]
Probable guanine nucleotide exchange factor MCF2L2 (MCF2L2)	OTOGFMIH	MF2L2_HUMAN	Increases Methylation	[14]
Protein O-mannosyl-transferase TMTC1 (TMTC1)	OTZ7NW96	TMTC1_HUMAN	Increases Methylation	[14]
Neuron navigator 3 (NAV3)	OT97M1TR	NAV3_HUMAN	Decreases Methylation	[14]
Glycerate kinase (GLYCTK)	OTVTBNSM	GLCTK_HUMAN	Increases Methylation	[14]
Aprataxin and PNK-like factor (APLF)	OTYUR3AH	APLF_HUMAN	Increases Expression	[16]
Adhesion G protein-coupled receptor A3 (ADGRA3)	OTPJEV0S	AGRA3_HUMAN	Increases Methylation	[14]
Proton-coupled zinc antiporter SLC30A8 (SLC30A8)	OTF0FG5K	ZNT8_HUMAN	Increases Methylation	[14]
Sphingosine-1-phosphate phosphatase 2 (SGPP2)	OTIDIJCR	SGPP2_HUMAN	Increases Methylation	[14]
Neuronal PAS domain-containing protein 3 (NPAS3)	OT8D1ILB	NPAS3_HUMAN	Increases Methylation	[14]
POU domain class 2-associating factor 2 (POU2AF2)	OTPBW3NC	OCAT1_HUMAN	Increases Methylation	[14]
Lamin tail domain-containing protein 2 (LMNTD2)	OTKGJ1ST	LMTD2_HUMAN	Increases Methylation	[14]
Nucleotidyltransferase MB21D2 (MB21D2)	OT5C4VVU	M21D2_HUMAN	Increases Methylation	[14]
PEX5-related protein (PEX5L)	OTLR4HSR	PEX5R_HUMAN	Decreases Methylation	[14]
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1)	OTVXQNOT	PELP1_HUMAN	Decreases Expression	[16]
Voltage-dependent calcium channel subunit alpha-2/delta-3 (CACNA2D3)	OTEH9HGE	CA2D3_HUMAN	Increases Methylation	[14]
Transcription initiation factor TFIID subunit 1-like (TAF1L)	OT9Z7EVA	TAF1L_HUMAN	Increases Methylation	[14]
Leucine-rich repeat LGI family member 2 (LGI2)	OTFJ2ZSG	LGI2_HUMAN	Decreases Methylation	[14]
Regulatory-associated protein of mTOR (RPTOR)	OT4TQZ9F	RPTOR_HUMAN	Increases Methylation	[14]
UPF0462 protein C4orf33 (C4ORF33)	OT3O3FC3	CD033_HUMAN	Decreases Methylation	[14]
Mesoderm induction early response protein 2 (MIER2)	OTYURSWD	MIER2_HUMAN	Increases Methylation	[14]
Xylosyl- and glucuronyltransferase LARGE2 (LARGE2)	OT5BZS3J	LARG2_HUMAN	Increases Methylation	[14]
Putative transporter SVOPL (SVOPL)	OTJ4G2ND	SVOPL_HUMAN	Increases Methylation	[14]
Follistatin-related protein 5 (FSTL5)	OT18C29S	FSTL5_HUMAN	Decreases Methylation	[14]
ADAMTS-like protein 1 (ADAMTSL1)	OTBNYF3F	ATL1_HUMAN	Increases Methylation	[14]
EF-hand domain-containing family member B (EFHB)	OT83HFEP	EFHB_HUMAN	Increases Methylation	[14]
Protein BANP (BANP)	OT1JMTBD	BANP_HUMAN	Increases Methylation	[14]
Sodium-dependent lysophosphatidylcholine symporter 1 (MFSD2A)	OTVG1VG0	NLS1_HUMAN	Increases Methylation	[14]
Kyphoscoliosis peptidase (KY)	OTK1L8VX	KY_HUMAN	Increases Methylation	[14]
Clarin-3 (CLRN3)	OTZDNL65	CLRN3_HUMAN	Increases Methylation	[14]
Exophilin-5 (EXPH5)	OTOMXDUO	EXPH5_HUMAN	Decreases Methylation	[14]
Nesprin-1 (SYNE1)	OTSBSLUH	SYNE1_HUMAN	Increases Methylation	[14]
Metalloreductase STEAP2 (STEAP2)	OTGE9ETG	STEA2_HUMAN	Decreases Methylation	[14]
Kelch repeat and BTB domain-containing protein 8 (KBTBD8)	OTO8X1UF	KBTB8_HUMAN	Decreases Methylation	[14]
Neuroligin-2 (NLGN2)	OTHDYL3H	NLGN2_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase Nek11 (NEK11)	OTMYENTC	NEK11_HUMAN	Decreases Methylation	[14]
Olfactory receptor 5T1 (OR5T1)	OTJT8C6S	OR5T1_HUMAN	Decreases Methylation	[14]
Olfactory receptor 2AK2 (OR2AK2)	OTNG4ZS1	O2AK2_HUMAN	Increases Methylation	[14]
Olfactory receptor 8J3 (OR8J3)	OTLQYWZG	OR8J3_HUMAN	Decreases Methylation	[14]
Olfactory receptor 8J1 (OR8J1)	OTWWGQW0	OR8J1_HUMAN	Decreases Methylation	[14]
Olfactory receptor 4S2 (OR4S2)	OTHEO86H	OR4S2_HUMAN	Decreases Methylation	[14]
LHFPL tetraspan subfamily member 5 protein (LHFPL5)	OTNDTO5B	LHPL5_HUMAN	Decreases Methylation	[14]
SWI/SNF complex subunit SMARCC2 (SMARCC2)	OTC5SNMZ	SMRC2_HUMAN	Decreases Expression	[35]
Iron-sulfur cluster transfer protein NUBPL (NUBPL)	OTQMCSXT	NUBPL_HUMAN	Increases Methylation	[14]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Increases Methylation	[14]
T-cell immunomodulatory protein (ITFG1)	OTX0PCR3	TIP_HUMAN	Decreases Methylation	[14]
Glutamate receptor ionotropic, NMDA 3A (GRIN3A)	OTQS9GYY	NMD3A_HUMAN	Increases Methylation	[14]
Transmembrane channel-like protein 1 (TMC1)	OTHYH8MU	TMC1_HUMAN	Increases Methylation	[14]
Polycystin-1-like protein 1 (PKD1L1)	OTLAARJ1	PK1L1_HUMAN	Increases Methylation	[14]
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (ASAP3)	OTQB4H1J	ASAP3_HUMAN	Increases Methylation	[14]
Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8L3)	OT7XYA2T	ES8L3_HUMAN	Increases Methylation	[14]
Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8L1)	OT83O8WI	ES8L1_HUMAN	Decreases Methylation	[14]
Importin-4 (IPO4)	OT2N5020	IPO4_HUMAN	Increases Methylation	[14]
Membrane progestin receptor beta (PAQR8)	OTGZ8W9F	PAQR8_HUMAN	Decreases Methylation	[14]
Dual specificity protein phosphatase 19 (DUSP19)	OT0RRSG9	DUS19_HUMAN	Decreases Methylation	[14]
Splicing factor Cactin (CACTIN)	OTO7UVK7	CATIN_HUMAN	Increases Methylation	[14]
AFG1-like ATPase (AFG1L)	OTQ9VV5T	AFG1L_HUMAN	Increases Methylation	[14]
Ankyrin repeat and SOCS box protein 10 (ASB10)	OTYSZ9V6	ASB10_HUMAN	Increases Methylation	[14]
Autism susceptibility gene 2 protein (AUTS2)	OTAEXHSC	AUTS2_HUMAN	Increases Methylation	[14]
Cysteine/serine-rich nuclear protein 3 (CSRNP3)	OTOANEHZ	CSRN3_HUMAN	Increases Methylation	[14]
Phosphoinositide 3-kinase regulatory subunit 5 (PIK3R5)	OT4LNXJU	PI3R5_HUMAN	Decreases Methylation	[14]
Piezo-type mechanosensitive ion channel component 1 (PIEZO1)	OTBG1FU4	PIEZ1_HUMAN	Increases Methylation	[14]
Phosphatidate phosphatase LPIN2 (LPIN2)	OTRRTMXX	LPIN2_HUMAN	Increases Methylation	[14]
Sorting nexin-19 (SNX19)	OTGNS3HG	SNX19_HUMAN	Decreases Methylation	[14]
Engulfment and cell motility protein 1 (ELMO1)	OTY2ORXK	ELMO1_HUMAN	Decreases Methylation	[14]
Delta-sarcoglycan (SGCD)	OTRBL3NQ	SGCD_HUMAN	Increases Methylation	[14]
A-kinase anchor protein 1, mitochondrial (AKAP1)	OTIIB2JB	AKAP1_HUMAN	Increases Expression	[16]
Estrogen receptor beta (ESR2)	OTXNR2WQ	ESR2_HUMAN	Increases Expression	[16]
Transcription initiation factor TFIID subunit 4B (TAF4B)	OTCICY31	TAF4B_HUMAN	Increases Methylation	[14]
General transcription factor IIH subunit 4 (GTF2H4)	OTPD1DIU	TF2H4_HUMAN	Decreases Methylation	[14]
Histone acetyltransferase KAT6A (KAT6A)	OT4TSQLG	KAT6A_HUMAN	Decreases Methylation	[14]
Neuronal cell adhesion molecule (NRCAM)	OT80HHQ2	NRCAM_HUMAN	Increases Methylation	[14]
Bcl-2-like protein 2 (BCL2L2)	OTMKVO0J	B2CL2_HUMAN	Increases Expression	[16]
Caspase-10 (CASP10)	OTE6J88E	CASPA_HUMAN	Increases Methylation	[14]
ATP-binding cassette sub-family C member 2 (ABCC2)	OTJSIGV5	MRP2_HUMAN	Increases Expression	[40]
Fibroblast growth factor 13 (FGF13)	OTHNNVSG	FGF13_HUMAN	Increases Methylation	[14]
SWI/SNF complex subunit SMARCC1 (SMARCC1)	OTUOMBE7	SMRC1_HUMAN	Increases Expression	[35]
Receptor-type tyrosine-protein phosphatase N2 (PTPRN2)	OTL6SH28	PTPR2_HUMAN	Increases Methylation	[14]
Lipoma-preferred partner (LPP)	OT6TU8SE	LPP_HUMAN	Increases Methylation	[14]
Mediator of RNA polymerase II transcription subunit 12 (MED12)	OTQZ4D2X	MED12_HUMAN	Increases Methylation	[14]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3)	OTFYDEES	AT2A3_HUMAN	Increases Methylation	[14]
Secretory carrier-associated membrane protein 4 (SCAMP4)	OTSCZTJ5	SCAM4_HUMAN	Increases Methylation	[14]
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1)	OT351FKB	ERGI1_HUMAN	Decreases Methylation	[14]
Terminal nucleotidyltransferase 5B (TENT5B)	OTO2P28B	TET5B_HUMAN	Increases Methylation	[14]
Collagen alpha-1(XXVI) chain (COL26A1)	OTMS7RNF	COQA1_HUMAN	Decreases Methylation	[14]
Isochorismatase domain-containing protein 2 (ISOC2)	OT69N6MB	ISOC2_HUMAN	Increases Methylation	[14]
Repulsive guidance molecule A (RGMA)	OTZAMDO2	RGMA_HUMAN	Increases Methylation	[14]
Dedicator of cytokinesis protein 10 (DOCK10)	OTI3MBLV	DOC10_HUMAN	Increases Methylation	[14]
EF-hand domain-containing protein D2 (EFHD2)	OTM9VMN3	EFHD2_HUMAN	Increases Methylation	[14]
Netrin-G2 (NTNG2)	OTTY88DL	NTNG2_HUMAN	Increases Methylation	[14]
Anaphase-promoting complex subunit 16 (ANAPC16)	OTG9MUYS	APC16_HUMAN	Increases Methylation	[14]
Rho guanine nucleotide exchange factor 26 (ARHGEF26)	OTX0U8PX	ARHGQ_HUMAN	Increases Methylation	[14]
PHD finger protein 21B (PHF21B)	OTU5GLCQ	PF21B_HUMAN	Increases Methylation	[14]
Polypeptide N-acetylgalactosaminyltransferase 14 (GALNT14)	OT9BSDDQ	GLT14_HUMAN	Increases Methylation	[14]
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7)	OTI7Q2JW	CKLF7_HUMAN	Decreases Methylation	[14]
Aurora kinase B (AURKB)	OTIY4VHU	AURKB_HUMAN	Decreases Expression	[15]
Protein FAM163A (FAM163A)	OT0MYZ0F	F163A_HUMAN	Increases Methylation	[14]
SH3 domain-containing YSC84-like protein 1 (SH3YL1)	OTVXOONW	SH3Y1_HUMAN	Increases Methylation	[14]
ATP-binding cassette sub-family C member 11 (ABCC11)	OTVHL7OR	MRP8_HUMAN	Increases Methylation	[14]
Cadherin-related family member 1 (CDHR1)	OT1ORXCM	CDHR1_HUMAN	Decreases Methylation	[14]
Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)	OTWV82RP	M4A4A_HUMAN	Decreases Methylation	[14]
Protein maelstrom homolog (MAEL)	OTZ2VU30	MAEL_HUMAN	Decreases Methylation	[14]
MAP/microtubule affinity-regulating kinase 4 (MARK4)	OT6Z2TGV	MARK4_HUMAN	Increases Methylation	[14]
Zeta-sarcoglycan (SGCZ)	OTVGTEOD	SGCZ_HUMAN	Decreases Methylation	[14]
Adenylate kinase 8 (AK8)	OT2UF6YM	KAD8_HUMAN	Decreases Methylation	[14]
bMERB domain-containing protein 1 (BMERB1)	OT1IH086	MERB1_HUMAN	Increases Methylation	[14]
Junctional sarcoplasmic reticulum protein 1 (JSRP1)	OT1AAYWO	JSPR1_HUMAN	Increases Methylation	[14]
Cytosolic carboxypeptidase 4 (AGBL1)	OT8NQLH0	CBPC4_HUMAN	Decreases Methylation	[14]
Nucleolar protein 4-like (NOL4L)	OT14W6UW	NOL4L_HUMAN	Increases Methylation	[14]
Retinol dehydrogenase 12 (RDH12)	OTELFRRJ	RDH12_HUMAN	Increases Methylation	[14]
N-terminal EF-hand calcium-binding protein 3 (NECAB3)	OTRASC9G	NECA3_HUMAN	Increases Methylation	[14]
Noelin-3 (OLFM3)	OTBHPDTL	NOE3_HUMAN	Decreases Methylation	[14]
Erythroid membrane-associated protein (ERMAP)	OTKXBB52	ERMAP_HUMAN	Decreases Methylation	[14]
CUB and sushi domain-containing protein 1 (CSMD1)	OTIVDSC4	CSMD1_HUMAN	Decreases Methylation	[14]
PHD finger protein 12 (PHF12)	OTECRO7N	PHF12_HUMAN	Increases Methylation	[14]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI1)	OTMV4ASV	MAGI1_HUMAN	Decreases Methylation	[14]
Olfactory receptor 8B4 (OR8B4)	OTT4T35X	OR8B4_HUMAN	Decreases Methylation	[14]
Galactose-3-O-sulfotransferase 4 (GAL3ST4)	OTCXGJGO	G3ST4_HUMAN	Increases Methylation	[14]
Erbin (ERBIN)	OTNWTUA8	ERBIN_HUMAN	Increases Methylation	[14]
Intraflagellar transport protein 140 homolog (IFT140)	OT6KO5FH	IF140_HUMAN	Increases Methylation	[14]
GPI transamidase component PIG-S (PIGS)	OTCC4CEN	PIGS_HUMAN	Increases Methylation	[14]
Tetraspanin-18 (TSPAN18)	OTHSGPVB	TSN18_HUMAN	Decreases Methylation	[14]
2-aminoethanethiol dioxygenase (ADO)	OTRLGQ7V	AEDO_HUMAN	Increases Methylation	[14]
Eyes absent homolog 1 (EYA1)	OTHU807A	EYA1_HUMAN	Decreases Methylation	[14]
G-protein coupled estrogen receptor 1 (GPER1)	OTUK0TDC	GPER1_HUMAN	Increases Expression	[49]
Prohibitin-2 (PHB2)	OTCAX3AW	PHB2_HUMAN	Decreases Expression	[16]
Ataxin-2 (ATXN2)	OT465IGT	ATX2_HUMAN	Increases Methylation	[14]
Tumor susceptibility gene 101 protein (TSG101)	OT97UIXC	TS101_HUMAN	Increases Methylation	[14]
Calcium and integrin-binding protein 1 (CIB1)	OT4BVCRU	CIB1_HUMAN	Increases Methylation	[14]
Histone H2B type 1-M (H2BC14)	OTSDZZZY	H2B1M_HUMAN	Increases Methylation	[14]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Increases Expression	[16]
Semaphorin-3C (SEMA3C)	OTEGUY7F	SEM3C_HUMAN	Increases Methylation	[14]
Testican-3 (SPOCK3)	OTYSOOO7	TICN3_HUMAN	Decreases Methylation	[14]
SH3-containing GRB2-like protein 3-interacting protein 1 (SGIP1)	OTQW6R3Z	SGIP1_HUMAN	Increases Methylation	[14]
Uncharacterized protein C7orf50 (C7ORF50)	OTDHN459	CG050_HUMAN	Increases Methylation	[14]
Ferroptosis suppressor protein 1 (AIFM2)	OT57XWXO	FSP1_HUMAN	Increases Methylation	[14]
Phagosome assembly factor 1 (PHAF1)	OTF7ZOG6	PHAF1_HUMAN	Increases Methylation	[14]
NEDD4 family-interacting protein 1 (NDFIP1)	OTIORSWF	NFIP1_HUMAN	Increases Methylation	[14]
Death-inducer obliterator 1 (DIDO1)	OT9PB547	DIDO1_HUMAN	Increases Methylation	[14]
CDK5 and ABL1 enzyme substrate 2 (CABLES2)	OTGD9A2A	CABL2_HUMAN	Increases Methylation	[14]
Tubulin-specific chaperone D (TBCD)	OTS4JKNQ	TBCD_HUMAN	Increases Methylation	[14]
E3 ubiquitin-protein ligase TRIM62 (TRIM62)	OT15YO6N	TRI62_HUMAN	Decreases Methylation	[14]
PHD finger protein 20 (PHF20)	OTCBVH5P	PHF20_HUMAN	Increases Methylation	[14]
Protein TALPID3 (KIAA0586)	OTOZRC1U	TALD3_HUMAN	Increases Methylation	[14]
Katanin p60 ATPase-containing subunit A-like 1 (KATNAL1)	OTBUZ7KA	KATL1_HUMAN	Increases Methylation	[14]
Chitinase domain-containing protein 1 (CHID1)	OT4DIUKC	CHID1_HUMAN	Decreases Methylation	[14]
Brother of CDO (BOC)	OTXBCY9W	BOC_HUMAN	Decreases Methylation	[14]
Sal-like protein 3 (SALL3)	OTJ2LZKQ	SALL3_HUMAN	Affects Methylation	[14]
Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4)	OTIMWEK5	LGR4_HUMAN	Increases Methylation	[14]
Hydroxycarboxylic acid receptor 1 (HCAR1)	OT5ZSESQ	HCAR1_HUMAN	Increases Methylation	[14]
Caspase recruitment domain-containing protein 11 (CARD11)	OTRCTLYC	CAR11_HUMAN	Increases Methylation	[14]
Calcium-binding protein 8 (CALN1)	OTN2XE4T	CABP8_HUMAN	Increases Methylation	[14]
R-spondin-3 (RSPO3)	OTZK8GDS	RSPO3_HUMAN	Increases Methylation	[14]
Histone deacetylase 8 (HDAC8)	OT5L4RYX	HDAC8_HUMAN	Increases Methylation	[14]
Dual specificity protein phosphatase 16 (DUSP16)	OTK7S078	DUS16_HUMAN	Decreases Methylation	[14]
Alpha-(1,6)-fucosyltransferase (FUT8)	OTJJCVG1	FUT8_HUMAN	Decreases Methylation	[14]
Hyccin (HYCC1)	OTO65AE3	HYCCI_HUMAN	Increases Methylation	[14]
Keratin-associated protein 2-1 (KRTAP2-1)	OTV1SGF2	KRA21_HUMAN	Increases Methylation	[14]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Increases Methylation	[14]
Reticulon-4 receptor (RTN4R)	OT8J693X	RTN4R_HUMAN	Increases Methylation	[14]
Forkhead box protein P3 (FOXP3)	OTA9Z9OC	FOXP3_HUMAN	Increases Methylation	[14]
E3 ubiquitin-protein ligase TRIM4 (TRIM4)	OTLKQNKQ	TRIM4_HUMAN	Increases Methylation	[14]
Tripartite motif-containing protein 2 (TRIM2)	OT0V1YVC	TRIM2_HUMAN	Increases Methylation	[14]
Cilia- and flagella-associated protein 74 (CFAP74)	OTVW2BGR	CFA74_HUMAN	Increases Methylation	[14]
SRC kinase signaling inhibitor 1 (SRCIN1)	OTQZNQQ5	SRCN1_HUMAN	Decreases Methylation	[14]
Eukaryotic translation initiation factor 5A-2 (EIF5A2)	OT4SY4KY	IF5A2_HUMAN	Decreases Methylation	[14]
Hyaluronan and proteoglycan link protein 2 (HAPLN2)	OT0G3KEQ	HPLN2_HUMAN	Decreases Methylation	[14]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP)	OT9AGAIJ	LHPP_HUMAN	Increases Methylation	[14]
Transmembrane protein 168 (TMEM168)	OTJKZ6G9	TM168_HUMAN	Increases Methylation	[14]
B-cell lymphoma/leukemia 11A (BCL11A)	OTI6ZBP6	BC11A_HUMAN	Increases Methylation	[14]
EH domain-containing protein 4 (EHD4)	OT7G5JTT	EHD4_HUMAN	Increases Methylation	[14]
Enhancer of polycomb homolog 1 (EPC1)	OT3Q25ND	EPC1_HUMAN	Increases Methylation	[14]
Sodium-coupled neutral amino acid symporter 1 (SLC38A1)	OTO3VD5E	S38A1_HUMAN	Increases Methylation	[14]
Chordin (CHRD)	OTNM60Y1	CHRD_HUMAN	Increases Methylation	[14]
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1)	OT38HXJP	CRLD1_HUMAN	Increases Methylation	[14]
Polyadenylate-binding protein 3 (PABPC3)	OTTR9DPT	PABP3_HUMAN	Increases Methylation	[14]
Tumor protein 63 (TP63)	OT0WOOKQ	P63_HUMAN	Increases Methylation	[14]
Thiamin pyrophosphokinase 1 (TPK1)	OTCHPUD0	TPK1_HUMAN	Increases Methylation	[14]
Homeodomain-interacting protein kinase 3 (HIPK3)	OT4WYQM2	HIPK3_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase PLK3 (PLK3)	OT19CT2Z	PLK3_HUMAN	Increases Methylation	[14]
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (ST6GALNAC4)	OTJCJQI7	SIA7D_HUMAN	Increases Methylation	[14]
PR domain zinc finger protein 13 (PRDM13)	OTUNAFQW	PRD13_HUMAN	Increases Methylation	[14]
Dual specificity protein phosphatase 21 (DUSP21)	OTZAGY5R	DUS21_HUMAN	Decreases Methylation	[14]
Uncharacterized protein C19orf44 (C19ORF44)	OTES5EZZ	CS044_HUMAN	Increases Methylation	[14]
Histone-lysine N-methyltransferase SMYD3 (SMYD3)	OT9YR20G	SMYD3_HUMAN	Affects Methylation	[14]
Proton-activated chloride channel (PACC1)	OTKBS8CC	PACC1_HUMAN	Increases Methylation	[14]
Tetratricopeptide repeat protein 12 (TTC12)	OTDB24YV	TTC12_HUMAN	Increases Methylation	[14]
Probable ATP-dependent RNA helicase DDX31 (DDX31)	OTNWY581	DDX31_HUMAN	Increases Methylation	[14]
Protein argonaute-3 (AGO3)	OTNQGROH	AGO3_HUMAN	Affects Methylation	[14]
Akirin-1 (AKIRIN1)	OTINWTT9	AKIR1_HUMAN	Increases Methylation	[14]
Homeobox protein NANOG (NANOG)	OTUEY1FM	NANOG_HUMAN	Increases Expression	[50]
Adhesion G protein-coupled receptor L3 (ADGRL3)	OT81Q8LY	AGRL3_HUMAN	Decreases Methylation	[14]
Protein ERGIC-53-like (LMAN1L)	OT2CSBR3	LMA1L_HUMAN	Increases Methylation	[14]
Histone-lysine N-methyltransferase PRDM16 (PRDM16)	OT0BGA27	PRD16_HUMAN	Decreases Methylation	[14]
Solute carrier family 38 member 10 (SLC38A10)	OTXPUL6S	S38AA_HUMAN	Increases Methylation	[14]
Mucin-5B (MUC5B)	OTPW6K5C	MUC5B_HUMAN	Increases Methylation	[14]
Transcription factor HES-4 (HES4)	OTCGMQDT	HES4_HUMAN	Increases Methylation	[14]
Helicase MOV-10 (MOV10)	OT0KAY9G	MOV10_HUMAN	Increases Methylation	[14]
Synaptotagmin-like protein 2 (SYTL2)	OTUIOWKL	SYTL2_HUMAN	Increases Methylation	[14]
E3 ubiquitin-protein ligase MSL2 (MSL2)	OTVPQYBG	MSL2_HUMAN	Increases Methylation	[14]
Mineralization regulator ANKH (ANKH)	OTCN25R5	ANKH_HUMAN	Decreases Methylation	[14]
Roundabout homolog 2 (ROBO2)	OTFJ9FQW	ROBO2_HUMAN	Decreases Methylation	[14]
Fibrosin-1-like protein (FBRSL1)	OT4BPXGG	FBSL_HUMAN	Increases Methylation	[14]
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A)	OT9X261C	PDE11_HUMAN	Increases Methylation	[14]
LYR motif-containing protein 4 (LYRM4)	OTK6JCKL	LYRM4_HUMAN	Increases Methylation	[14]
Regulation of nuclear pre-mRNA domain-containing protein 1B (RPRD1B)	OTB41D5K	RPR1B_HUMAN	Increases Methylation	[14]
Gephyrin (GPHN)	OTAKK1SV	GEPH_HUMAN	Increases Methylation	[14]
Transcriptional and immune response regulator (TCIM)	OTARUXQF	TCIM_HUMAN	Increases Expression	[16]
Matrix-remodeling-associated protein 5 (MXRA5)	OTXZBWCU	MXRA5_HUMAN	Decreases Methylation	[14]
CTP synthase 2 (CTPS2)	OT2X9YO1	PYRG2_HUMAN	Increases Methylation	[14]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)	OTWHOVZS	BAZ1A_HUMAN	Increases Methylation	[14]
Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9)	OTENU71Z	GTR9_HUMAN	Increases Methylation	[14]
Interleukin-17 receptor B (IL17RB)	OT0KDNSF	I17RB_HUMAN	Decreases Expression	[15]
Double-stranded RNA-specific editase B2 (ADARB2)	OTDJKS39	RED2_HUMAN	Increases Methylation	[14]
Protein DEPP1 (DEPP1)	OTB36PHJ	DEPP1_HUMAN	Decreases Expression	[32]
E3 ubiquitin-protein ligase RNF146 (RNF146)	OTE4CO7E	RN146_HUMAN	Decreases Methylation	[14]
Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)	OTORNUIF	STAU2_HUMAN	Decreases Methylation	[14]
tRNA:m(4)X modification enzyme TRM13 homolog (TRMT13)	OT2H0MCE	TRM13_HUMAN	Increases Methylation	[14]
F-box only protein 28 (FBXO28)	OTKTMVC4	FBX28_HUMAN	Decreases Methylation	[14]
Transmembrane protein 51 (TMEM51)	OTZCW8XJ	TMM51_HUMAN	Increases Methylation	[14]
Solute carrier family 52, riboflavin transporter, member 1 (SLC52A1)	OTQ4D276	S52A1_HUMAN	Increases Methylation	[14]
CUE domain-containing protein 1 (CUEDC1)	OTQ7V4FF	CUED1_HUMAN	Increases Methylation	[14]
Membrane progestin receptor gamma (PAQR5)	OTGGWXQE	PAQR5_HUMAN	Increases Methylation	[14]
Rho guanine nucleotide exchange factor 38 (ARHGEF38)	OTA6K93F	ARH38_HUMAN	Increases Methylation	[14]
Odorant-binding protein 2a (OBP2A)	OTBIJ5TI	OBP2A_HUMAN	Increases Methylation	[14]
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8)	OTPT2I7B	SL2A8_HUMAN	Increases Methylation	[14]
Sodium channel regulatory subunit beta-3 (SCN3B)	OTNTQT9O	SCN3B_HUMAN	Decreases Methylation	[14]
Probable ATP-dependent RNA helicase DDX56 (DDX56)	OTGURA53	DDX56_HUMAN	Increases Methylation	[14]
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (COA4)	OT8319UQ	COA4_HUMAN	Increases Methylation	[14]
24-hydroxycholesterol 7-alpha-hydroxylase (CYP39A1)	OTBAJT4I	CP39A_HUMAN	Increases Methylation	[14]
Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1)	OT7PS8O1	CELR1_HUMAN	Increases Methylation	[14]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (SMARCAL1)	OTTKXLUZ	SMAL1_HUMAN	Decreases Methylation	[14]
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)	OT9G360P	IF2B1_HUMAN	Increases Methylation	[14]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Increases Methylation	[14]
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1)	OTW3T4B2	IRPL1_HUMAN	Decreases Methylation	[14]
CXXC-type zinc finger protein 1 (CXXC1)	OTO10D1N	CXXC1_HUMAN	Decreases Methylation	[14]
Neurotrimin (NTM)	OTHF0UQU	NTRI_HUMAN	Decreases Methylation	[14]
Costars family protein ABRACL (ABRACL)	OT95T48Q	ABRAL_HUMAN	Increases Methylation	[14]
Coiled-coil domain-containing protein 180 (CCDC180)	OT4AL3LW	CC180_HUMAN	Increases Methylation	[14]
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 (NYAP2)	OT80PO4Q	NYAP2_HUMAN	Increases Methylation	[14]
Rho GTPase-activating protein 20 (ARHGAP20)	OTG1STV8	RHG20_HUMAN	Increases Methylation	[14]
KAT8 regulatory NSL complex subunit 3 (KANSL3)	OTWXDTLY	KANL3_HUMAN	Decreases Methylation	[14]
Arginine-glutamic acid dipeptide repeats protein (RERE)	OT3G4GBZ	RERE_HUMAN	Increases Methylation	[14]
Sperm microtubule associated protein 2 (SPMAP2)	OTLJPJ39	SPMA2_HUMAN	Increases Methylation	[14]
Protein IMPACT (IMPACT)	OTQ923OB	IMPCT_HUMAN	Increases Methylation	[14]
Copine-7 (CPNE7)	OTR0FJ8A	CPNE7_HUMAN	Increases Methylation	[14]
Dickkopf-related protein 3 (DKK3)	OTDU94EY	DKK3_HUMAN	Increases Methylation	[14]
PTB domain-containing engulfment adapter protein 1 (GULP1)	OT1WMVDH	GULP1_HUMAN	Increases Methylation	[14]
Gamma-aminobutyric acid type B receptor subunit 1 (GABBR1)	OTU5A52J	GABR1_HUMAN	Increases Methylation	[14]
Alpha-catulin (CTNNAL1)	OTESJ6JD	CTNL1_HUMAN	Increases Methylation	[14]
Protein CLN8 (CLN8)	OT0D4CB5	CLN8_HUMAN	Decreases Methylation	[14]
Tripartite motif-containing protein 10 (TRIM10)	OTEO4UCZ	TRI10_HUMAN	Increases Methylation	[14]
Death domain-associated protein 6 (DAXX)	OTX6O7PL	DAXX_HUMAN	Increases Methylation	[14]
tRNA (FTSJ1)	OTNE7W96	TRM7_HUMAN	Increases Methylation	[14]
Dynein axonemal heavy chain 17 (DNAH17)	OT4G6E70	DYH17_HUMAN	Increases Methylation	[14]
Regulator of G-protein signaling 17 (RGS17)	OT5RVUDS	RGS17_HUMAN	Decreases Methylation	[14]
Olfactory receptor 12D3 (OR12D3)	OTQ9XNBB	O12D3_HUMAN	Increases Methylation	[14]
Deleted in malignant brain tumors 1 protein (DMBT1)	OTVNU9D9	DMBT1_HUMAN	Increases Expression	[51]
Switch-associated protein 70 (SWAP70)	OTPHT2QD	SWP70_HUMAN	Decreases Methylation	[14]
Contactin-associated protein-like 2 (CNTNAP2)	OT48T2ZP	CNTP2_HUMAN	Increases Methylation	[14]
Interleukin-17B (IL17B)	OTS86H50	IL17B_HUMAN	Decreases Methylation	[14]
Sodium channel protein type 11 subunit alpha (SCN11A)	OTY0HJJZ	SCNBA_HUMAN	Increases Methylation	[14]
Cardiolipin synthase (CRLS1)	OT7XNL0K	CRLS1_HUMAN	Decreases Methylation	[14]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (ENPP5)	OTY807N5	ENPP5_HUMAN	Decreases Methylation	[14]
Anaphase-promoting complex subunit 2 (ANAPC2)	OTAGLIAO	ANC2_HUMAN	Increases Methylation	[14]
ADP-ribosylation factor-binding protein GGA1 (GGA1)	OTSEV0JU	GGA1_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase tousled-like 1 (TLK1)	OTICTXI8	TLK1_HUMAN	Increases Methylation	[14]
POU domain, class 2, transcription factor 3 (POU2F3)	OTIOOJWD	PO2F3_HUMAN	Increases Methylation	[14]
Mucin-12 (MUC12)	OTYDC13T	MUC12_HUMAN	Increases Methylation	[14]
F-box only protein 5 (FBXO5)	OTTR957W	FBX5_HUMAN	Decreases Expression	[15]
Histone deacetylase 9 (HDAC9)	OTO8O0LF	HDAC9_HUMAN	Decreases Methylation	[14]
Protein argonaute-2 (AGO2)	OT4JY32Q	AGO2_HUMAN	Increases Methylation	[14]
Bromodomain and PHD finger-containing protein 3 (BRPF3)	OTRNO4PR	BRPF3_HUMAN	Increases Methylation	[14]
DENN domain-containing protein 2A (DENND2A)	OT01E1PL	DEN2A_HUMAN	Increases Methylation	[14]
Cell cycle progression protein 1 (CCPG1)	OT0IHDKL	CCPG1_HUMAN	Increases Methylation	[14]
Myocardin-related transcription factor B (MRTFB)	OT9OXGS9	MRTFB_HUMAN	Decreases Methylation	[14]
Protein HEG homolog 1 (HEG1)	OT3CUXA7	HEG1_HUMAN	Increases Methylation	[14]
Glutamate receptor ionotropic, delta-1 (GRID1)	OTJ3WIKC	GRID1_HUMAN	Increases Methylation	[14]
Transcription factor MafF (MAFF)	OT9B7MX0	MAFF_HUMAN	Increases Expression	[16]
Protein ATP1B4 (ATP1B4)	OT2YC9GZ	AT1B4_HUMAN	Decreases Methylation	[14]
Dual specificity protein phosphatase CDC14A (CDC14A)	OTL10OY6	CC14A_HUMAN	Increases Methylation	[14]
FAS-associated factor 1 (FAF1)	OTGAMLM4	FAF1_HUMAN	Increases Methylation	[14]
Protein timeless homolog (TIMELESS)	OTD8DCBJ	TIM_HUMAN	Decreases Expression	[15]
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1)	OTVIHD77	MACF1_HUMAN	Increases Methylation	[14]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1)	OTVX8835	AGAP1_HUMAN	Affects Methylation	[14]
Trinucleotide repeat-containing gene 6B protein (TNRC6B)	OTGVT0SH	TNR6B_HUMAN	Increases Methylation	[14]
Transcription factor 19 (TCF19)	OT7NKLF9	TCF19_HUMAN	Decreases Expression	[15]
Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)	OTB17Q43	SIA10_HUMAN	Increases Methylation	[14]
UDP-N-acetylglucosamine transporter (SLC35A3)	OTG92DK5	S35A3_HUMAN	Increases Methylation	[14]
Protein strawberry notch homolog 2 (SBNO2)	OT1C6J3K	SBNO2_HUMAN	Increases Methylation	[14]
Angiomotin-like protein 2 (AMOTL2)	OTRCTKV9	AMOL2_HUMAN	Increases Methylation	[14]
Serine/threonine-protein kinase SIK3 (SIK3)	OTH0V1L5	SIK3_HUMAN	Increases Methylation	[14]
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1)	OTS5S837	PPIL1_HUMAN	Increases Methylation	[14]
Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)	OT8M52QY	LMBL1_HUMAN	Decreases Methylation	[14]
Transformation/transcription domain-associated protein (TRRAP)	OT68OI2Y	TRRAP_HUMAN	Increases Methylation	[14]
FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1)	OTL1EBTM	FARP1_HUMAN	Increases Methylation	[14]
Centrosomal protein of 170 kDa protein B (CEP170B)	OTYB0VGH	C170B_HUMAN	Increases Methylation	[14]
Protein PRRC2C (PRRC2C)	OTBX3MXM	PRC2C_HUMAN	Increases Methylation	[14]
Ankyrin repeat and SOCS box protein 4 (ASB4)	OTI4AFZL	ASB4_HUMAN	Increases Methylation	[14]
Ankyrin repeat and SOCS box protein 3 (ASB3)	OTI3TK38	ASB3_HUMAN	Decreases Methylation	[14]
AP-4 complex subunit sigma-1 (AP4S1)	OTM3QBU8	AP4S1_HUMAN	Decreases Methylation	[14]
Protocadherin gamma-A1 (PCDHGA1)	OTR1U1LI	PCDG1_HUMAN	Increases Methylation	[14]
Methyltransferase N6AMT1 (N6AMT1)	OTOK0NYQ	N6MT1_HUMAN	Increases Methylation	[14]
Sorting nexin-8 (SNX8)	OTMG63Z6	SNX8_HUMAN	Increases Methylation	[14]
Nuclear receptor corepressor 2 (NCOR2)	OTY917X0	NCOR2_HUMAN	Increases Methylation	[14]
Junctional adhesion molecule A (F11R)	OTGHPAV6	JAM1_HUMAN	Decreases Methylation	[14]
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (ARFGEF1)	OTPAU0L4	BIG1_HUMAN	Increases Methylation	[14]
Synphilin-1 (SNCAIP)	OTH8VNOK	SNCAP_HUMAN	Increases Methylation	[14]
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L)	OTQLO30U	TAF6L_HUMAN	Increases Methylation	[14]
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)	OT4ZSEEE	IF2B2_HUMAN	Increases Methylation	[14]
Nuclear receptor coactivator 3 (NCOA3)	OTBX300Z	NCOA3_HUMAN	Increases Expression	[16]
Calmodulin-binding transcription activator 1 (CAMTA1)	OTAN1S5B	CMTA1_HUMAN	Increases Methylation	[14]
Ras-related and estrogen-regulated growth inhibitor (RERG)	OTF6MMLV	RERG_HUMAN	Affects Response To Substance	[35]
Serine/threonine-protein kinase mTOR (MTOR)	OTHH8KU7	MTOR_HUMAN	Decreases Response To Substance	[15]
Breast cancer anti-estrogen resistance protein 3 (BCAR3)	OTPJ17M8	BCAR3_HUMAN	Affects Response To Substance	[35]
FK506-binding protein-like (FKBPL)	OTR9ND6K	FKBPL_HUMAN	Increases Response To Substance	[52]
Anterior gradient protein 2 homolog (AGR2)	OTRRZT7W	AGR2_HUMAN	Affects Response To Substance	[53]
AT-rich interactive domain-containing protein 1A (ARID1A)	OTRWDV3P	ARI1A_HUMAN	Decreases Response To Substance	[54]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)	OTW8V2V1	ABCG2_HUMAN	Affects Response To Substance	[35]
Artemin (ARTN)	OTWIWGL6	ARTN_HUMAN	Decreases Response To Substance	[55]
Cyclin-dependent kinase 12 (CDK12)	OTZUDGNU	CDK12_HUMAN	Affects Response To Substance	[56]

Indication(s) of Methotrexate

Disease Entry	ICD 11	Status	REF
Anterior urethra cancer	N.A.	Approved	[3]
Burkitt lymphoma	N.A.	Approved	[3]
Childhood acute lymphoblastic leukemia	N.A.	Approved	[3]
Choriocarcinoma	2C75.0	Approved	[4]
Gestational trophoblastic neoplasia	2F33-2F76	Approved	[3]
Head and neck cancer	2D42	Approved	[3]
Inflammation	1A00-CA43.1	Approved	[3]
leukaemia	2A60-2B33	Approved	[5]
Leukemia	N.A.	Approved	[3]
Lung cancer	2C25.0	Approved	[3]
Mycosis fungoides	2B01	Approved	[3]
Posterior urethra cancer	N.A.	Approved	[3]
Psoriasis	EA90	Approved	[3]
Sensorineural hearing loss disorder	N.A.	Approved	[3]
Urticaria	EB00-EB05	Approved	[3]
Proliferative vitreoretinopathy	9B78.2	Phase 3	[6]
Solid tumour/cancer	2A00-2F9Z	Phase 3	[5]
Coronavirus Disease 2019 (COVID-19)	1D6Y	Phase 1/2	[7]
Rheumatoid arthritis	FA20	Phase 1	[8]
Prostate cancer	2C82.0	Investigative	[9]

Methotrexate Interacts with 2 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Proton-coupled folate transporter (SLC46A1)	TTY8Z2E	PCFT_HUMAN	Modulator	[75]
Solute carrier family 19 member 1 (SLC19A1)	TT09I7D	S19A1_HUMAN	Modulator	[76]

Methotrexate Interacts with 17 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
Multidrug resistance-associated protein 1 (ABCC1)	DTSYQGK	MRP1_HUMAN	Substrate	[77]
Multidrug resistance-associated protein 2 (ABCC2)	DTFI42L	MRP2_HUMAN	Substrate	[78]
P-glycoprotein 1 (ABCB1)	DTUGYRD	MDR1_HUMAN	Substrate	[79]
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[80]
Organic anion transporter 2 (SLC22A7)	DT0OC1Q	S22A7_HUMAN	Substrate	[81]
Organic anion transporting polypeptide 1B1 (SLCO1B1)	DT3D8F0	SO1B1_HUMAN	Substrate	[82]
Multidrug resistance-associated protein 3 (ABCC3)	DTQ3ZHF	MRP3_HUMAN	Substrate	[83]
Multidrug resistance-associated protein 4 (ABCC4)	DTCSGPB	MRP4_HUMAN	Substrate	[84]
Multidrug resistance-associated protein 5 (ABCC5)	DTYVM24	MRP5_HUMAN	Substrate	[85]
Organic anion transporter 1 (SLC22A6)	DTQ23VB	S22A6_HUMAN	Substrate	[86]
Organic anion transporter 3 (SLC22A8)	DTVP67E	S22A8_HUMAN	Substrate	[87]
Organic anion transporter 4 (SLC22A11)	DT06JWZ	S22AB_HUMAN	Substrate	[88]
Organic anion transporting polypeptide 1A2 (SLCO1A2)	DTE2B1D	SO1A2_HUMAN	Substrate	[89]
Organic anion transporting polypeptide 1B3 (SLCO1B3)	DT9C1TS	SO1B3_HUMAN	Substrate	[90]
Multidrug resistance-associated protein 8 (ABCC11)	DTWN7FC	ABCCB_HUMAN	Substrate	[91]
Folate transporter 1 (SLC19A1)	DTOSN46	S19A1_HUMAN	Substrate	[92]
Proton-coupled folate transporter (SLC46A1)	DTDJEMI	PCFT_HUMAN	Substrate	[93]

Methotrexate Interacts with 7 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Thiopurine methyltransferase (TPMT)	DEFQ8VO	TPMT_HUMAN	Metabolism	[94]
Methylenetetrahydrofolate reductase (MTHFR)	DEOXTPZ	MTHR_HUMAN	Metabolism	[95]
Thymidylate synthase (TYMS)	DEASG0Q	TYSY_HUMAN	Metabolism	[95]
Dihydrofolate reductase (DHFR)	DE4EGMZ	DYR_HUMAN	Metabolism	[95]
Gamma-Glu-X carboxypeptidase (GGH)	DEU7MWJ	GGH_HUMAN	Metabolism	[95]
Folylpolyglutamate synthase (FPGS)	DECWT2V	FOLC_HUMAN	Metabolism	[95]
Glutamate carboxypeptidase II (FOLH1)	DEN8V7Z	FOLH1_HUMAN	Metabolism	[96]

Methotrexate Interacts with 1626 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Thiopurine S-methyltransferase (TPMT)	OTFOX70W	TPMT_HUMAN	Decreases Expression	[62]
Gamma-glutamyl hydrolase (GGH)	OTL71J7T	GGH_HUMAN	Decreases Expression	[97]
Dihydrofolate reductase (DHFR)	OT3DVIGM	DYR_HUMAN	Decreases Response To Substance	[98]
Solute carrier family 22 member 7 (SLC22A7)	OTKTNH1W	S22A7_HUMAN	Increases Expression	[62]
ATP-binding cassette sub-family C member 4 (ABCC4)	OTO27PAL	MRP4_HUMAN	Decreases Expression	[97]
ATP-binding cassette sub-family C member 2 (ABCC2)	OTJSIGV5	MRP2_HUMAN	Increases Expression	[97]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)	OTW8V2V1	ABCG2_HUMAN	Increases Expression	[64]
Multidrug resistance-associated protein 1 (ABCC1)	OTGUN89S	MRP1_HUMAN	Decreases Expression	[97]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Increases Expression	[99]
ATP-binding cassette sub-family C member 5 (ABCC5)	OT34G4US	MRP5_HUMAN	Decreases Expression	[97]
Solute carrier organic anion transporter family member 1B1 (SLCO1B1)	OTNEN8QK	SO1B1_HUMAN	Increases Response To Substance	[100]
Proton-coupled folate transporter (SLC46A1)	OT049V7Y	PCFT_HUMAN	Increases Response To Substance	[100]
Reduced folate transporter (SLC19A1)	OTWB0BTO	S19A1_HUMAN	Decreases Response To Substance	[101]
Solute carrier family 22 member 6 (SLC22A6)	OTKRCBVM	S22A6_HUMAN	Increases Response To Substance	[102]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Affects Response To Substance	[103]
Organic anion transporter 3 (SLC22A8)	OT8BY933	S22A8_HUMAN	Increases Response To Substance	[102]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Decreases Expression	[58]
Sulfotransferase 1E1 (SULT1E1)	OTGPJ517	ST1E1_HUMAN	Increases Expression	[104]
Sulfotransferase 1A1 (SULT1A1)	OT0K7JIE	ST1A1_HUMAN	Increases Expression	[104]
Arylamine N-acetyltransferase 1 (NAT1)	OTCCNQ3H	ARY1_HUMAN	Decreases Activity	[105]
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Decreases Expression	[106]
TANK-binding kinase 1-binding protein 1 (TBKBP1)	OTXTU37H	TBKB1_HUMAN	Decreases Expression	[58]
Alternative prion protein (PRNP)	OTE85L1Q	APRIO_HUMAN	Decreases Expression	[58]
AH receptor-interacting protein (AIP)	OTDJ3OSV	AIP_HUMAN	Increases Expression	[58]
Toll-like receptor 4 (TLR4)	OTP7ML3S	TLR4_HUMAN	Decreases Expression	[58]
C-C motif chemokine 21 (CCL21)	OT7DOXEM	CCL21_HUMAN	Decreases Expression	[58]
Peroxisomal targeting signal 2 receptor (PEX7)	OTM7VBRC	PEX7_HUMAN	Increases Expression	[58]
Acetyl-CoA carboxylase 2 (ACACB)	OT96UIP1	ACACB_HUMAN	Increases Expression	[58]
Stearoyl-CoA desaturase (SCD)	OTB1073G	SCD_HUMAN	Increases Expression	[58]
AP-3 complex subunit delta-1 (AP3D1)	OTJLI0IM	AP3D1_HUMAN	Decreases Expression	[58]
C-X-C motif chemokine 11 (CXCL11)	OT353XE3	CXL11_HUMAN	Decreases Expression	[58]
Syntaxin-16 (STX16)	OTM7TAOE	STX16_HUMAN	Increases Expression	[58]
Phytanoyl-CoA dioxygenase, peroxisomal (PHYH)	OTUG4BWA	PAHX_HUMAN	Increases Expression	[58]
Long-chain fatty acid transport protein 2 (SLC27A2)	OT7JEG5F	S27A2_HUMAN	Increases Expression	[58]
Synaptojanin-2 (SYNJ2)	OTLRHXP1	SYNJ2_HUMAN	Increases Expression	[58]
FYN-binding protein 1 (FYB1)	OT6345CH	FYB1_HUMAN	Decreases Expression	[58]
Phospholipid scramblase 1 (PLSCR1)	OTGY9B5T	PLS1_HUMAN	Decreases Expression	[58]
C-C motif chemokine 25 (CCL25)	OTLWJ8CJ	CCL25_HUMAN	Decreases Expression	[58]
DNA-directed RNA polymerase I subunit RPA34 (POLR1G)	OTEGR9C2	RPA34_HUMAN	Decreases Expression	[58]
Plexin-B1 (PLXNB1)	OTCA7JIT	PLXB1_HUMAN	Increases Expression	[58]
Hypocretin neuropeptide precursor (HCRT)	OTQ4FGI9	OREX_HUMAN	Decreases Expression	[58]
Transcription factor 21 (TCF21)	OT393IMA	TCF21_HUMAN	Decreases Expression	[58]
Acyl-CoA (FADS1)	OTUYOYHX	FADS1_HUMAN	Increases Expression	[58]
Long-chain-fatty-acid--CoA ligase 4 (ACSL4)	OTI71MUJ	ACSL4_HUMAN	Increases Expression	[58]
Target of Myb1 membrane trafficking protein (TOM1)	OT30QA56	TOM1_HUMAN	Decreases Expression	[58]
Receptor activity-modifying protein 1 (RAMP1)	OT7UT2XB	RAMP1_HUMAN	Decreases Expression	[58]
Receptor activity-modifying protein 2 (RAMP2)	OTGQXLH5	RAMP2_HUMAN	Decreases Expression	[58]
Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B)	OTSLSPZG	FCG3B_HUMAN	Decreases Expression	[58]
ICOS ligand (ICOSLG)	OTAD976B	ICOSL_HUMAN	Decreases Expression	[58]
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5)	OTMVHF9E	LGR5_HUMAN	Decreases Expression	[58]
Protein XRP2 (RP2)	OTK050I3	XRP2_HUMAN	Increases Expression	[58]
Diacylglycerol O-acyltransferase 1 (DGAT1)	OTL104WL	DGAT1_HUMAN	Increases Expression	[58]
DnaJ homolog subfamily B member 5 (DNAJB5)	OT7WDJ5C	DNJB5_HUMAN	Decreases Expression	[58]
Cystatin-F (CST7)	OTQWZUVQ	CYTF_HUMAN	Decreases Expression	[58]
SUN domain-containing protein 1 (SUN1)	OTIU8V4U	SUN1_HUMAN	Increases Expression	[58]
Nuclear factor of activated T-cells 5 (NFAT5)	OTKIE59S	NFAT5_HUMAN	Increases Expression	[58]
Interleukin-18 receptor accessory protein (IL18RAP)	OTCUB1EV	I18RA_HUMAN	Decreases Expression	[58]
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8)	OT1G9297	TFIP8_HUMAN	Decreases Expression	[58]
Fibroblast growth factor 19 (FGF19)	OT2DVJWY	FGF19_HUMAN	Decreases Expression	[58]
Putative lipid scramblase CLPTM1 (CLPTM1)	OT14QP7N	CLPT1_HUMAN	Decreases Expression	[58]
Mitochondrial import receptor subunit TOM40 homolog (TOMM40)	OTZDQ29F	TOM40_HUMAN	Increases Expression	[58]
Hypoxanthine-guanine phosphoribosyltransferase (HPRT1)	OTOEEEXG	HPRT_HUMAN	Decreases Expression	[58]
Prothrombin (F2)	OTNFSM49	THRB_HUMAN	Increases Expression	[58]
Complement C3 (C3)	OTCH5GS0	CO3_HUMAN	Increases Expression	[58]
Complement C5 (C5)	OTSL3OIC	CO5_HUMAN	Increases Expression	[58]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[58]
Platelet-derived growth factor subunit B (PDGFB)	OTMFMFC3	PDGFB_HUMAN	Decreases Expression	[58]
Transforming growth factor beta-1 proprotein (TGFB1)	OTV5XHVH	TGFB1_HUMAN	Decreases Expression	[58]
Beta-nerve growth factor (NGF)	OTOLABJT	NGF_HUMAN	Increases Expression	[58]
Prolactin (PRL)	OTWFQGX7	PRL_HUMAN	Decreases Expression	[58]
Insulin (INS)	OTZ85PDU	INS_HUMAN	Decreases Expression	[58]
Interferon gamma (IFNG)	OTXG9JM7	IFNG_HUMAN	Decreases Expression	[58]
Interleukin-1 alpha (IL1A)	OTPSGILV	IL1A_HUMAN	Decreases Expression	[58]
HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA)	OT7KZMP2	DRA_HUMAN	Decreases Expression	[58]
Myelin basic protein (MBP)	OTFZCEDB	MBP_HUMAN	Increases Expression	[58]
Complement C1q subcomponent subunit B (C1QB)	OT2G1IOX	C1QB_HUMAN	Decreases Expression	[58]
Fibronectin (FN1)	OTB5ZN4Q	FINC_HUMAN	Increases Expression	[58]
Platelet factor 4 (PF4)	OTEMJU68	PLF4_HUMAN	Decreases Expression	[58]
Plasma kallikrein (KLKB1)	OTGSEISX	KLKB1_HUMAN	Increases Expression	[58]
Catalase (CAT)	OTHEBX9R	CATA_HUMAN	Increases Expression	[58]
Glucocorticoid receptor (NR3C1)	OTCI2YDI	GCR_HUMAN	Decreases Expression	[58]
Amyloid-beta precursor protein (APP)	OTKFD7R4	A4_HUMAN	Decreases Expression	[58]
Interleukin-4 (IL4)	OTOXBWAU	IL4_HUMAN	Decreases Expression	[58]
Insulin receptor (INSR)	OTTY341H	INSR_HUMAN	Increases Expression	[58]
Protein S100-A9 (S100A9)	OTOARHCS	S10A9_HUMAN	Decreases Expression	[58]
T-cell surface antigen CD2 (CD2)	OTLYO0DB	CD2_HUMAN	Decreases Expression	[58]
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)	OTREV92I	CEAM5_HUMAN	Increases Expression	[58]
Fatty acid-binding protein, liver (FABP1)	OTR34ETM	FABPL_HUMAN	Increases Expression	[58]
Vitamin K-dependent protein S (PROS1)	OTXQWNOI	PROS_HUMAN	Increases Expression	[58]
Macrophage colony-stimulating factor 1 receptor (CSF1R)	OTDYTB9C	CSF1R_HUMAN	Decreases Expression	[58]
Complement component C8 alpha chain (C8A)	OTIJ65J4	CO8A_HUMAN	Increases Expression	[58]
Pulmonary surfactant-associated protein B (SFTPB)	OTOHS07E	PSPB_HUMAN	Decreases Expression	[58]
Thrombospondin-1 (THBS1)	OT0ECWK3	TSP1_HUMAN	Decreases Expression	[58]
Cathepsin G (CTSG)	OT85ZMQG	CATG_HUMAN	Decreases Expression	[58]
Receptor-type tyrosine-protein phosphatase C (PTPRC)	OT6KOR77	PTPRC_HUMAN	Decreases Expression	[58]
Integrin alpha-5 (ITGA5)	OT3RCI67	ITA5_HUMAN	Increases Expression	[58]
Interleukin-3 (IL3)	OT0CQ35N	IL3_HUMAN	Decreases Expression	[58]
Glutathione S-transferase A2 (GSTA2)	OTW7UB1H	GSTA2_HUMAN	Increases Expression	[58]
CD48 antigen (CD48)	OT83ZNPP	CD48_HUMAN	Decreases Expression	[58]
Macrophage colony-stimulating factor 1 (CSF1)	OT68M7RD	CSF1_HUMAN	Decreases Expression	[58]
Heat shock 70 kDa protein 1A (HSPA1A)	OTKGIE76	HS71A_HUMAN	Decreases Expression	[58]
C-C motif chemokine 3 (CCL3)	OTW2H3ND	CCL3_HUMAN	Decreases Expression	[58]
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT)	OT9LBJVN	ODP2_HUMAN	Increases Expression	[58]
T-cell-specific surface glycoprotein CD28 (CD28)	OTT5XJST	CD28_HUMAN	Decreases Expression	[58]
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM)	OTA4P0FC	ACADM_HUMAN	Increases Expression	[58]
Steroid hormone receptor ERR1 (ESRRA)	OTTDTUSP	ERR1_HUMAN	Decreases Expression	[58]
Aromatase (CYP19A1)	OTZ6XF74	CP19A_HUMAN	Increases Expression	[58]
Cytochrome c oxidase subunit 6A1, mitochondrial (COX6A1)	OT77MV8G	CX6A1_HUMAN	Decreases Expression	[58]
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2)	OTPG0K7E	IMDH2_HUMAN	Decreases Expression	[58]
Low affinity immunoglobulin gamma Fc region receptor II-a (FCGR2A)	OT0OUDUT	FCG2A_HUMAN	Increases Expression	[58]
Granzyme A (GZMA)	OT43R33L	GRAA_HUMAN	Decreases Expression	[58]
Proto-oncogene tyrosine-protein kinase Src (SRC)	OTETYX40	SRC_HUMAN	Decreases Expression	[58]
C-C motif chemokine 2 (CCL2)	OTAD2HEL	CCL2_HUMAN	Decreases Expression	[58]
C-C motif chemokine 5 (CCL5)	OTSCA5CK	CCL5_HUMAN	Decreases Expression	[58]
L-selectin (SELL)	OT6RAJZR	LYAM1_HUMAN	Decreases Expression	[58]
Phospholipase A2, membrane associated (PLA2G2A)	OT1NY7BF	PA2GA_HUMAN	Increases Expression	[58]
Interleukin-2 receptor subunit beta (IL2RB)	OT6M0F70	IL2RB_HUMAN	Decreases Expression	[58]
Cytochrome c oxidase subunit 6B1 (COX6B1)	OTNKXYQI	CX6B1_HUMAN	Decreases Expression	[58]
B-lymphocyte antigen CD19 (CD19)	OTCPF9NF	CD19_HUMAN	Decreases Expression	[58]
15-hydroxyprostaglandin dehydrogenase (HPGD)	OTYZI6JB	PGDH_HUMAN	Increases Expression	[58]
Antigen-presenting glycoprotein CD1d (CD1D)	OT3ROU4J	CD1D_HUMAN	Increases Expression	[58]
SH2/SH3 adapter protein NCK1 (NCK1)	OTKYZ4OP	NCK1_HUMAN	Decreases Expression	[58]
C-C motif chemokine 3-like 1 (CCL3L1)	OTQXCYB1	CL3L1_HUMAN	Decreases Expression	[58]
HLA class I histocompatibility antigen, alpha chain G (HLA-G)	OTMLK1KN	HLAG_HUMAN	Decreases Expression	[58]
Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12)	OTFL5KR5	LOX12_HUMAN	Decreases Expression	[58]
Lipopolysaccharide-binding protein (LBP)	OTQXAH4L	LBP_HUMAN	Increases Expression	[58]
Lymphocyte function-associated antigen 3 (CD58)	OTIUGMGS	LFA3_HUMAN	Increases Expression	[58]
Spermidine synthase (SRM)	OT4N5MDP	SPEE_HUMAN	Decreases Expression	[58]
L-serine dehydratase/L-threonine deaminase (SDS)	OT5WTJ2M	SDHL_HUMAN	Increases Expression	[58]
Integrin alpha-L (ITGAL)	OTCUQAIS	ITAL_HUMAN	Increases Expression	[58]
Mimecan (OGN)	OTKP5S4L	MIME_HUMAN	Decreases Expression	[58]
Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1)	OT6QGM5Y	IMDH1_HUMAN	Decreases Expression	[58]
T-cell surface glycoprotein CD3 zeta chain (CD247)	OT45FGUX	CD3Z_HUMAN	Decreases Expression	[58]
fMet-Leu-Phe receptor (FPR1)	OTFF9I6W	FPR1_HUMAN	Decreases Expression	[58]
Kit ligand (KITLG)	OTB9AVQ4	SCF_HUMAN	Decreases Expression	[58]
C5a anaphylatoxin chemotactic receptor 1 (C5AR1)	OT58QDI9	C5AR1_HUMAN	Decreases Expression	[58]
Tumor necrosis factor ligand superfamily member 4 (TNFSF4)	OTOCBX7P	TNFL4_HUMAN	Increases Expression	[58]
Trans-acting T-cell-specific transcription factor GATA-3 (GATA3)	OTGP7D5Y	GATA3_HUMAN	Increases Expression	[58]
Interleukin-32 (IL32)	OT3FHZ81	IL32_HUMAN	Decreases Expression	[58]
Myeloblastin (PRTN3)	OT72MHP7	PRTN3_HUMAN	Decreases Expression	[58]
Tenascin (TNC)	OTK4FSHR	TENA_HUMAN	Increases Expression	[58]
Deoxyribonuclease-1 (DNASE1)	OTM4KWB3	DNAS1_HUMAN	Increases Expression	[58]
C-X-C chemokine receptor type 2 (CXCR2)	OTISGW7L	CXCR2_HUMAN	Decreases Expression	[58]
N-formyl peptide receptor 2 (FPR2)	OTEZ2THZ	FPR2_HUMAN	Decreases Expression	[58]
Cathepsin S (CTSS)	OT3PXIPM	CATS_HUMAN	Decreases Expression	[58]
Interleukin-1 receptor type 2 (IL1R2)	OT0G7E35	IL1R2_HUMAN	Decreases Expression	[58]
ATP-binding cassette sub-family D member 3 (ABCD3)	OT2PITLX	ABCD3_HUMAN	Increases Expression	[58]
T-cell surface glycoprotein CD1b (CD1B)	OT4D5EG7	CD1B_HUMAN	Decreases Expression	[58]
Enoyl-CoA hydratase, mitochondrial (ECHS1)	OTS0593S	ECHM_HUMAN	Increases Expression	[58]
High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G)	OTBZBL9Y	FCERG_HUMAN	Decreases Expression	[58]
Coronin-1A (CORO1A)	OTVAZOHC	COR1A_HUMAN	Decreases Expression	[58]
Protein S100-A11 (S100A11)	OTI57KDN	S10AB_HUMAN	Decreases Expression	[58]
Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B)	OTCJD51H	FCG2B_HUMAN	Decreases Expression	[58]
G-protein coupled receptor 183 (GPR183)	OTRILX7G	GP183_HUMAN	Decreases Expression	[58]
ETS-related transcription factor Elf-1 (ELF1)	OTV5LKIA	ELF1_HUMAN	Decreases Expression	[58]
Lymphocyte-specific protein 1 (LSP1)	OTSPSIFO	LSP1_HUMAN	Increases Expression	[58]
ATP-binding cassette sub-family D member 1 (ABCD1)	OT3FL9W0	ABCD1_HUMAN	Decreases Expression	[58]
Heat shock 70 kDa protein 4 (HSPA4)	OT5HR0AR	HSP74_HUMAN	Increases Expression	[58]
Gap junction alpha-4 protein (GJA4)	OTUPCT1V	CXA4_HUMAN	Decreases Expression	[58]
Pro-adrenomedullin (ADM)	OT7T0TA4	ADML_HUMAN	Decreases Expression	[58]
Histamine H1 receptor (HRH1)	OT8F9FV6	HRH1_HUMAN	Increases Expression	[58]
Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)	OTNWEJ5Y	PCKGC_HUMAN	Increases Expression	[58]
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3)	OTZG1W8W	CEAM3_HUMAN	Decreases Expression	[58]
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6)	OTQOUHVK	CEAM6_HUMAN	Increases Expression	[58]
Trifunctional enzyme subunit alpha, mitochondrial (HADHA)	OTO557N2	ECHA_HUMAN	Increases Expression	[58]
Kappa-type opioid receptor (OPRK1)	OTXCZF4L	OPRK_HUMAN	Increases Expression	[58]
Regulator of G-protein signaling 2 (RGS2)	OT0FSRW7	RGS2_HUMAN	Decreases Expression	[58]
Patatin-like phospholipase domain-containing protein 4 (PNPLA4)	OT5CVDJM	PLPL4_HUMAN	Decreases Expression	[58]
Neuroblastoma suppressor of tumorigenicity 1 (NBL1)	OTT37U4O	NBL1_HUMAN	Decreases Expression	[58]
Tumor necrosis factor ligand superfamily member 9 (TNFSF9)	OTV9L89D	TNFL9_HUMAN	Decreases Expression	[58]
T-lymphocyte activation antigen CD86 (CD86)	OTJCSBPC	CD86_HUMAN	Decreases Expression	[58]
Signal transducer and activator of transcription 5A (STAT5A)	OTBSJGN3	STA5A_HUMAN	Decreases Expression	[58]
3-ketoacyl-CoA thiolase, mitochondrial (ACAA2)	OTGLVWOP	THIM_HUMAN	Increases Expression	[58]
Stromal cell-derived factor 1 (CXCL12)	OT2QX5LL	SDF1_HUMAN	Increases Expression	[58]
Paxillin (PXN)	OTVMMUOF	PAXI_HUMAN	Increases Expression	[58]
Natural resistance-associated macrophage protein 1 (SLC11A1)	OTCN8N8B	NRAM1_HUMAN	Decreases Expression	[58]
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL)	OT50L4XB	ACADV_HUMAN	Increases Expression	[58]
Regulator of G-protein signaling 4 (RGS4)	OTG94HHL	RGS4_HUMAN	Decreases Expression	[58]
Tuberin (TSC2)	OT47LWI9	TSC2_HUMAN	Increases Expression	[58]
Selenoprotein P (SELENOP)	OT02B8IR	SEPP1_HUMAN	Increases Expression	[58]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)	OTI862QH	CPT1A_HUMAN	Increases Expression	[58]
Serpin H1 (SERPINH1)	OTKGI7BS	SERPH_HUMAN	Decreases Expression	[58]
Peroxisomal multifunctional enzyme type 2 (HSD17B4)	OT8733D7	DHB4_HUMAN	Increases Expression	[58]
Eotaxin (CCL11)	OT3BIFPK	CCL11_HUMAN	Decreases Expression	[58]
Tyrosine-protein kinase JAK3 (JAK3)	OTQ8QW2L	JAK3_HUMAN	Decreases Expression	[58]
Rho GDP-dissociation inhibitor 2 (ARHGDIB)	OT9PD6CS	GDIR2_HUMAN	Decreases Expression	[58]
GTP-binding protein GEM (GEM)	OT6SK8ZV	GEM_HUMAN	Decreases Expression	[58]
Fibroblast growth factor 8 (FGF8)	OTFU0IUW	FGF8_HUMAN	Decreases Expression	[58]
Microfibril-associated glycoprotein 4 (MFAP4)	OT5W64QY	MFAP4_HUMAN	Decreases Expression	[58]
Trifunctional enzyme subunit beta, mitochondrial (HADHB)	OT4Y1I62	ECHB_HUMAN	Increases Expression	[58]
Proteinase-activated receptor 2 (F2RL1)	OTMRMJ8N	PAR2_HUMAN	Increases Expression	[58]
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ)	OT7B6C6M	ATP68_HUMAN	Decreases Expression	[58]
SCAN domain-containing protein 1 (SCAND1)	OTRG0AGH	SCND1_HUMAN	Decreases Expression	[58]
CD81 antigen (CD81)	OTQFXNAZ	CD81_HUMAN	Increases Expression	[58]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)	OTOWDUNT	PTEN_HUMAN	Increases Expression	[58]
Large ribosomal subunit protein uL24 (RPL26)	OTFNRC27	RL26_HUMAN	Decreases Expression	[58]
Fibroblast growth factor 12 (FGF12)	OTBM9QIO	FGF12_HUMAN	Decreases Expression	[58]
Proline-rich protein 3 (PRR3)	OTCWSM5T	PRR3_HUMAN	Decreases Expression	[58]
C-C motif chemokine 8 (CCL8)	OTCTWYN8	CCL8_HUMAN	Decreases Expression	[58]
Small EDRK-rich factor 2 (SERF2)	OTZQDYCZ	SERF2_HUMAN	Decreases Expression	[58]
Cytochrome c (CYCS)	OTBFALJD	CYC_HUMAN	Increases Expression	[58]
Transcription factor RelB (RELB)	OTU3QYEF	RELB_HUMAN	Decreases Expression	[58]
Interleukin-1 receptor-like 1 (IL1RL1)	OTJ6MW31	ILRL1_HUMAN	Decreases Expression	[58]
Inositol polyphosphate 5-phosphatase OCRL (OCRL)	OTQ3L42N	OCRL_HUMAN	Increases Expression	[58]
DNA-binding protein inhibitor ID-3 (ID3)	OTUULW5Z	ID3_HUMAN	Decreases Expression	[58]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1)	OTF6OC66	GCNT1_HUMAN	Increases Expression	[58]
Cytochrome P450 4A11 (CYP4A11)	OTPU5J0S	CP4AB_HUMAN	Increases Expression	[58]
Peroxisome proliferator-activated receptor delta (PPARD)	OTI4WTOP	PPARD_HUMAN	Decreases Expression	[58]
Acetylcholine receptor subunit epsilon (CHRNE)	OTGGXGGB	ACHE_HUMAN	Decreases Expression	[58]
Dual specificity protein phosphatase 2 (DUSP2)	OTH54FMR	DUS2_HUMAN	Decreases Expression	[58]
Tumor necrosis factor receptor superfamily member 9 (TNFRSF9)	OTNOM26L	TNR9_HUMAN	Decreases Expression	[58]
Peroxisome proliferator-activated receptor alpha (PPARA)	OTK095PP	PPARA_HUMAN	Increases Expression	[58]
Regulator of G-protein signaling 1 (RGS1)	OTGXJYMG	RGS1_HUMAN	Decreases Expression	[58]
Peroxisomal bifunctional enzyme (EHHADH)	OTBAAHL5	ECHP_HUMAN	Increases Expression	[58]
Cytochrome P450 4F3 (CYP4F3)	OTYNSQAM	CP4F3_HUMAN	Increases Expression	[58]
Leukocyte surface antigen CD47 (CD47)	OTLDZ0KZ	CD47_HUMAN	Decreases Expression	[58]
Nuclear factor of activated T-cells, cytoplasmic 3 (NFATC3)	OTYOORME	NFAC3_HUMAN	Increases Expression	[58]
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1)	OTA0UNHM	ECH1_HUMAN	Increases Expression	[58]
TNF receptor-associated factor 3 (TRAF3)	OT5TQBGV	TRAF3_HUMAN	Increases Expression	[58]
Natural killer cells antigen CD94 (KLRD1)	OTMYLOV4	KLRD1_HUMAN	Decreases Expression	[58]
Interleukin-15 receptor subunit alpha (IL15RA)	OTXP1QC5	I15RA_HUMAN	Decreases Expression	[58]
Myotubularin (MTM1)	OT3B517W	MTM1_HUMAN	Increases Expression	[58]
Methylglutaconyl-CoA hydratase, mitochondrial (AUH)	OT8VKBXX	AUHM_HUMAN	Increases Expression	[58]
Pro-interleukin-16 (IL16)	OTZ2MO6B	IL16_HUMAN	Decreases Expression	[58]
Interleukin-18 (IL18)	OTBB2A8O	IL18_HUMAN	Increases Expression	[58]
Next to BRCA1 gene 1 protein (NBR1)	OTVRL7J9	NBR1_HUMAN	Increases Expression	[58]
EKC/KEOPS complex subunit LAGE3 (LAGE3)	OTKBQHZI	LAGE3_HUMAN	Decreases Expression	[58]
Signal transducer and activator of transcription 4 (STAT4)	OTAK3VFR	STAT4_HUMAN	Increases Expression	[58]
Caspase-8 (CASP8)	OTA8TVI8	CASP8_HUMAN	Increases Expression	[58]
Neutrophil cytosol factor 4 (NCF4)	OTX007YL	NCF4_HUMAN	Decreases Expression	[58]
Splicing factor 3B subunit 3 (SF3B3)	OTAC9LZT	SF3B3_HUMAN	Decreases Expression	[58]
Protein transport protein Sec23B (SEC23B)	OT2NFSIQ	SC23B_HUMAN	Decreases Expression	[58]
Metastasis-suppressor KiSS-1 (KISS1)	OT6IE3K2	KISS1_HUMAN	Decreases Expression	[58]
Probable E3 ubiquitin-protein ligase HERC1 (HERC1)	OT73FVYZ	HERC1_HUMAN	Increases Expression	[58]
Interleukin-17A (IL17A)	OTY72FT2	IL17_HUMAN	Decreases Expression	[58]
Prostacyclin synthase (PTGIS)	OTT3RW6N	PTGIS_HUMAN	Decreases Expression	[58]
Keratin, type II cytoskeletal 71 (KRT71)	OTI91X9Z	K2C71_HUMAN	Decreases Expression	[58]
Pyrroline-5-carboxylate reductase 3 (PYCR3)	OT3SHY2S	P5CR3_HUMAN	Decreases Expression	[58]
Torsin-2A (TOR2A)	OT1EGCDU	TOR2A_HUMAN	Decreases Expression	[58]
Collectin-12 (COLEC12)	OTIQTK9G	COL12_HUMAN	Decreases Expression	[58]
ER membrane protein complex subunit 10 (EMC10)	OTQ6S50X	EMC10_HUMAN	Decreases Expression	[58]
Protein angel homolog 2 (ANGEL2)	OT2Q1KU5	ANGE2_HUMAN	Increases Expression	[58]
Nucleoredoxin (NXN)	OT35N40G	NXN_HUMAN	Decreases Expression	[58]
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH)	OTU2VHWR	HIBCH_HUMAN	Increases Expression	[58]
Nucleolus and neural progenitor protein (NEPRO)	OTE5H49L	NEPRO_HUMAN	Increases Expression	[58]
Long-chain fatty acid transport protein 1 (SLC27A1)	OTK03OZN	S27A1_HUMAN	Decreases Expression	[58]
Kelch domain-containing protein 10 (KLHDC10)	OTLDF1OX	KLD10_HUMAN	Increases Expression	[58]
Mucin-6 (MUC6)	OTPVL723	MUC6_HUMAN	Decreases Expression	[58]
Cytochrome P450 4V2 (CYP4V2)	OTQKNK0D	CP4V2_HUMAN	Increases Expression	[58]
Fatty acid 2-hydroxylase (FA2H)	OT8HA13U	FA2H_HUMAN	Decreases Expression	[58]
Phospholipid phosphatase-related protein type 4 (PLPPR4)	OTBOWTC5	PLPR4_HUMAN	Decreases Expression	[58]
Adiponectin receptor protein 2 (ADIPOR2)	OT2HDTL8	PAQR2_HUMAN	Increases Expression	[58]
Ras-specific guanine nucleotide-releasing factor RalGPS2 (RALGPS2)	OTOYS0SD	RGPS2_HUMAN	Increases Expression	[58]
SURP and G-patch domain-containing protein 2 (SUGP2)	OTPUUJYX	SUGP2_HUMAN	Increases Expression	[58]
Spindle and kinetochore-associated protein 3 (SKA3)	OTLHEVJD	SKA3_HUMAN	Decreases Expression	[58]
NAD-dependent protein deacetylase sirtuin-2 (SIRT2)	OT5Q6SVK	SIR2_HUMAN	Decreases Expression	[58]
Threonine synthase-like 1 (THNSL1)	OTQNFH3E	THNS1_HUMAN	Decreases Expression	[58]
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2)	OT0HFPCD	LIRB2_HUMAN	Decreases Expression	[58]
Coiled-coil domain-containing protein 82 (CCDC82)	OT16EAZ7	CCD82_HUMAN	Increases Expression	[58]
Leucine repeat adapter protein 25 (FAM89B)	OT11J9HL	LRA25_HUMAN	Decreases Expression	[58]
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (MINDY1)	OTVLF4G5	MINY1_HUMAN	Increases Expression	[58]
Programmed cell death protein 7 (PDCD7)	OTK5YO7J	PDCD7_HUMAN	Increases Expression	[58]
Trinucleotide repeat-containing gene 6A protein (TNRC6A)	OT493IOM	TNR6A_HUMAN	Increases Expression	[58]
Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1)	OTA1STFZ	LIRB1_HUMAN	Decreases Expression	[58]
N-lysine methyltransferase SETD6 (SETD6)	OTH5APN1	SETD6_HUMAN	Increases Expression	[58]
DmX-like protein 2 (DMXL2)	OTB4JWN3	DMXL2_HUMAN	Increases Expression	[58]
DIS3-like exonuclease 1 (DIS3L)	OTYWZ4EM	DI3L1_HUMAN	Increases Expression	[58]
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIL4)	OTFTLFJS	PPIL4_HUMAN	Increases Expression	[58]
Spindle and kinetochore-associated protein 2 (SKA2)	OTVYF4XT	SKA2_HUMAN	Decreases Expression	[58]
Fatty acyl-CoA reductase 1 (FAR1)	OTLHTYIE	FACR1_HUMAN	Decreases Expression	[58]
Solute carrier organic anion transporter family member 2A1 (SLCO2A1)	OT3062CA	SO2A1_HUMAN	Decreases Expression	[58]
Glycine N-acyltransferase-like protein 1 (GLYATL1)	OTS8JSRY	GLYL1_HUMAN	Increases Expression	[58]
Adiponectin receptor protein 1 (ADIPOR1)	OT65ZFZN	PAQR1_HUMAN	Increases Expression	[58]
Probable inactive tRNA-specific adenosine deaminase-like protein 3 (ADAT3)	OTMEU45R	ADAT3_HUMAN	Decreases Expression	[58]
Multidrug and toxin extrusion protein 1 (SLC47A1)	OTZX0U5Q	S47A1_HUMAN	Increases Expression	[58]
Kelch domain-containing protein 7B (KLHDC7B)	OT2H5BNX	KLD7B_HUMAN	Decreases Expression	[58]
RUS family member 1 (RUSF1)	OTRIIY6J	RUSF1_HUMAN	Decreases Expression	[58]
Hematopoietic SH2 domain-containing protein (HSH2D)	OTOGB2BR	HSH2D_HUMAN	Increases Expression	[58]
Mas-related G-protein coupled receptor member X2 (MRGPRX2)	OT2XA799	MRGX2_HUMAN	Decreases Expression	[58]
Cilia- and flagella-associated protein 44 (CFAP44)	OT1273MD	CFA44_HUMAN	Increases Expression	[58]
Diacylglycerol O-acyltransferase 2 (DGAT2)	OTE5PDD0	DGAT2_HUMAN	Increases Expression	[58]
Inositol polyphosphate-4-phosphatase type I A (INPP4A)	OT8FZB8T	INP4A_HUMAN	Decreases Expression	[58]
Granulocyte colony-stimulating factor receptor (CSF3R)	OTXRAY6X	CSF3R_HUMAN	Decreases Expression	[58]
Transcription factor 12 (TCF12)	OTZVONNU	HTF4_HUMAN	Increases Expression	[58]
C-C motif chemokine 13 (CCL13)	OTNX0JD0	CCL13_HUMAN	Decreases Expression	[58]
Zinc finger protein Gfi-1 (GFI1)	OT9HB9H8	GFI1_HUMAN	Decreases Expression	[58]
C-C motif chemokine 19 (CCL19)	OTQ2UJMH	CCL19_HUMAN	Decreases Expression	[58]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Increases Expression	[58]
Adenine nucleotide translocase lysine N-methyltransferase (ANTKMT)	OTDV54V6	ANKMT_HUMAN	Decreases Expression	[58]
Protein FAM167B (FAM167B)	OT45SD3K	F167B_HUMAN	Decreases Expression	[58]
Enoyl- reductase, mitochondrial (MECR)	OTJQ5XKQ	MECR_HUMAN	Increases Expression	[58]
Peroxisomal trans-2-enoyl-CoA reductase (PECR)	OT5MS8EM	PECR_HUMAN	Increases Expression	[58]
Ras-related protein Rab-6C (RAB6C)	OTA66R5E	RAB6C_HUMAN	Decreases Expression	[58]
Semaphorin-4A (SEMA4A)	OT8901H3	SEM4A_HUMAN	Decreases Expression	[58]
UPF0488 protein C8orf33 (C8ORF33)	OTFCF3V5	CH033_HUMAN	Decreases Expression	[58]
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (RSAD1)	OTHNSDGW	RSAD1_HUMAN	Increases Expression	[58]
MLX-interacting protein (MLXIP)	OT30UNI7	MLXIP_HUMAN	Increases Expression	[58]
Solute carrier family 38 member 10 (SLC38A10)	OTXPUL6S	S38AA_HUMAN	Decreases Expression	[58]
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2)	OTPGYWKC	NOD2_HUMAN	Decreases Expression	[58]
Mineralization regulator ANKH (ANKH)	OTCN25R5	ANKH_HUMAN	Increases Expression	[58]
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM)	OTR1XD9B	GPAT1_HUMAN	Increases Expression	[58]
Complement component C1q receptor (CD93)	OT6HZT6H	C1QR1_HUMAN	Decreases Expression	[58]
Achaete-scute homolog 3 (ASCL3)	OT1Y3M4K	ASCL3_HUMAN	Decreases Expression	[58]
Protein transport protein Sec31B (SEC31B)	OTHV632I	SC31B_HUMAN	Increases Expression	[58]
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2)	OTB1FZJU	ACSA_HUMAN	Increases Expression	[58]
Sphingosine kinase 2 (SPHK2)	OTNFG52M	SPHK2_HUMAN	Decreases Expression	[58]
Interleukin-17 receptor B (IL17RB)	OT0KDNSF	I17RB_HUMAN	Increases Expression	[58]
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3)	OTAUR5TG	PLCC_HUMAN	Increases Expression	[58]
Keratin, type II cuticular Hb2 (KRT82)	OT8Y9T1U	KRT82_HUMAN	Decreases Expression	[58]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3)	OTR4990X	PLPL3_HUMAN	Increases Expression	[58]
PI-PLC X domain-containing protein 1 (PLCXD1)	OTU7KCQL	PLCX1_HUMAN	Increases Expression	[58]
Interleukin-1 receptor-associated kinase 4 (IRAK4)	OT9JTJWC	IRAK4_HUMAN	Increases Expression	[58]
Sphingosine kinase 1 (SPHK1)	OTWYPBVD	SPHK1_HUMAN	Decreases Expression	[58]
Protein Mis18-alpha (MIS18A)	OTD80K5X	MS18A_HUMAN	Decreases Expression	[58]
Protein CLN8 (CLN8)	OT0D4CB5	CLN8_HUMAN	Increases Expression	[58]
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1)	OTM3H5OA	MALT1_HUMAN	Increases Expression	[58]
Prenylcysteine oxidase 1 (PCYOX1)	OT8FBKY0	PCYOX_HUMAN	Increases Expression	[58]
Alpha-methylacyl-CoA racemase (AMACR)	OTUU22PK	AMACR_HUMAN	Increases Expression	[58]
A disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAMTS7)	OTVKZ1DV	ATS7_HUMAN	Decreases Expression	[58]
Long-chain-fatty-acid--CoA ligase 6 (ACSL6)	OT0TT8P8	ACSL6_HUMAN	Increases Expression	[58]
Teneurin-1 (TENM1)	OTSKSU4V	TEN1_HUMAN	Decreases Expression	[58]
Serine/threonine-protein kinase TAO2 (TAOK2)	OTNUMOZ1	TAOK2_HUMAN	Decreases Expression	[58]
Two pore channel protein 1 (TPCN1)	OTT4C4DI	TPC1_HUMAN	Increases Expression	[58]
Apelin (APLN)	OTSWJD7B	APEL_HUMAN	Decreases Expression	[58]
Myotubularin-related protein 7 (MTMR7)	OT47NVYM	MTMR7_HUMAN	Decreases Expression	[58]
Ninein-like protein (NINL)	OTWIK6HT	NINL_HUMAN	Increases Expression	[58]
Potassium channel subfamily K member 7 (KCNK7)	OTFJOWT4	KCNK7_HUMAN	Decreases Expression	[58]
Krueppel-like factor 2 (KLF2)	OTIP1UFX	KLF2_HUMAN	Decreases Expression	[58]
Neuroplastin (NPTN)	OTAQKSAU	NPTN_HUMAN	Decreases Expression	[58]
Inositol 1,4,5-triphosphate receptor associated 1 (IRAG1)	OTMRW5U5	IRAG1_HUMAN	Decreases Expression	[58]
Mitochondrial inner membrane protease ATP23 homolog (ATP23)	OT303R2T	ATP23_HUMAN	Increases Expression	[58]
Lymphocyte antigen 96 (LY96)	OTN4HXA2	LY96_HUMAN	Decreases Expression	[58]
Phospholipid-transporting ATPase ABCA1 (ABCA1)	OT94G6BQ	ABCA1_HUMAN	Increases Expression	[107]
Sterol 26-hydroxylase, mitochondrial (CYP27A1)	OT649C01	CP27A_HUMAN	Increases Expression	[107]
CCN family member 1 (CCN1)	OTKJBEMD	CCN1_HUMAN	Increases Expression	[59]
Phospholipid phosphatase 3 (PLPP3)	OTSSF7BK	PLPP3_HUMAN	Decreases Expression	[59]
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3)	OTPGHZB9	IFIT3_HUMAN	Decreases Expression	[59]
Calmegin (CLGN)	OTEWVFQV	CLGN_HUMAN	Decreases Expression	[59]
D-3-phosphoglycerate dehydrogenase (PHGDH)	OT1LMRTG	SERA_HUMAN	Decreases Expression	[59]
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2)	OT0KMIYQ	RIPK2_HUMAN	Decreases Expression	[59]
Gasdermin-E (GSDME)	OT1ZWY32	GSDME_HUMAN	Decreases Expression	[59]
Toll-like receptor 2 (TLR2)	OTGO5P4R	TLR2_HUMAN	Decreases Expression	[59]
Ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3)	OTDA431Y	ENTP3_HUMAN	Increases Expression	[59]
Antiviral innate immune response receptor RIG-I (RIGI)	OTFIIC43	RIGI_HUMAN	Decreases Expression	[59]
2'-5'-oligoadenylate synthase 1 (OAS1)	OT8ZLOCY	OAS1_HUMAN	Decreases Expression	[59]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Decreases Expression	[59]
Ubiquitin-like protein ISG15 (ISG15)	OT53QQ7N	ISG15_HUMAN	Decreases Expression	[59]
Fibroblast growth factor 1 (FGF1)	OT8I64X8	FGF1_HUMAN	Increases Expression	[59]
Interleukin-6 (IL6)	OTUOSCCU	IL6_HUMAN	Decreases Expression	[59]
Asparagine synthetase (ASNS)	OT8R922G	ASNS_HUMAN	Decreases Expression	[59]
Hepatocyte growth factor receptor (MET)	OT7K55MU	MET_HUMAN	Decreases Expression	[59]
Steryl-sulfatase (STS)	OTXTJQPC	STS_HUMAN	Increases Expression	[59]
Neuromedin-B (NMB)	OT4NLN6H	NMB_HUMAN	Decreases Expression	[59]
Stromelysin-2 (MMP10)	OTJDWW8Q	MMP10_HUMAN	Decreases Expression	[59]
Interferon alpha-inducible protein 6 (IFI6)	OTWOOAM4	IFI6_HUMAN	Decreases Expression	[59]
Interleukin-1 receptor antagonist protein (IL1RN)	OT308CBE	IL1RA_HUMAN	Decreases Expression	[59]
Interferon-induced GTP-binding protein Mx1 (MX1)	OT6X8G5T	MX1_HUMAN	Decreases Expression	[59]
Fibroblast growth factor 7 (FGF7)	OTGK6ANL	FGF7_HUMAN	Increases Expression	[59]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Increases Expression	[59]
Atypical chemokine receptor 3 (ACKR3)	OTA6GA4F	ACKR3_HUMAN	Decreases Expression	[59]
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1)	OTO7FJA9	DHI1_HUMAN	Decreases Expression	[59]
Myristoylated alanine-rich C-kinase substrate (MARCKS)	OT7N056G	MARCS_HUMAN	Decreases Expression	[59]
Guanylate-binding protein 1 (GBP1)	OTUM7RPJ	GBP1_HUMAN	Decreases Expression	[59]
Prostaglandin G/H synthase 2 (PTGS2)	OT75U9M4	PGH2_HUMAN	Decreases Expression	[59]
Macrophage metalloelastase (MMP12)	OT9Z7LHM	MMP12_HUMAN	Decreases Expression	[59]
Interferon alpha-inducible protein 27, mitochondrial (IFI27)	OTI2XGIT	IFI27_HUMAN	Decreases Expression	[59]
Signal transducer and activator of transcription 1-alpha/beta (STAT1)	OTLMBUZ6	STAT1_HUMAN	Decreases Expression	[59]
Retinoic acid receptor responder protein 1 (RARRES1)	OTETUPP5	TIG1_HUMAN	Increases Expression	[59]
Prolargin (PRELP)	OT9EEBUJ	PRELP_HUMAN	Increases Expression	[59]
Spermine synthase (SMS)	OT8JYKNH	SPSY_HUMAN	Decreases Expression	[59]
C-X-C chemokine receptor type 4 (CXCR4)	OTUFSBX2	CXCR4_HUMAN	Decreases Expression	[59]
C-C motif chemokine 20 (CCL20)	OTUCJY4N	CCL20_HUMAN	Decreases Expression	[59]
Interferon-induced 35 kDa protein (IFI35)	OTV9RZ53	IN35_HUMAN	Decreases Expression	[59]
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2)	OTRZH80H	TNAP2_HUMAN	Decreases Expression	[59]
Bone marrow stromal antigen 2 (BST2)	OTU4LCJV	BST2_HUMAN	Decreases Expression	[59]
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)	OTZVUOOB	FBLN3_HUMAN	Increases Expression	[59]
Probable ATP-dependent RNA helicase DDX10 (DDX10)	OTH48438	DDX10_HUMAN	Increases Expression	[59]
Neuronal membrane glycoprotein M6-b (GPM6B)	OT8Q1582	GPM6B_HUMAN	Increases Expression	[59]
Laminin subunit beta-3 (LAMB3)	OTFPU6W8	LAMB3_HUMAN	Decreases Expression	[59]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2)	OTTUU92F	ENPP2_HUMAN	Increases Expression	[59]
Nidogen-2 (NID2)	OTHC33FF	NID2_HUMAN	Increases Expression	[59]
Lymphocyte antigen 6E (LY6E)	OTMG16BZ	LY6E_HUMAN	Decreases Expression	[59]
Interferon-induced protein 44-like (IFI44L)	OTXKORJP	IF44L_HUMAN	Decreases Expression	[59]
E3 ubiquitin-protein ligase RNF19B (RNF19B)	OTYCWKBP	RN19B_HUMAN	Decreases Expression	[59]
Amphoterin-induced protein 2 (AMIGO2)	OTPAIT1O	AMGO2_HUMAN	Decreases Expression	[59]
Probable E3 ubiquitin-protein ligase HERC6 (HERC6)	OT7G9PQE	HERC6_HUMAN	Decreases Expression	[59]
Interferon-induced protein 44 (IFI44)	OTOKSZVA	IFI44_HUMAN	Decreases Expression	[59]
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2)	OTCA9WCM	RSAD2_HUMAN	Decreases Expression	[59]
Nuclear receptor subfamily 4 group A member 3 (NR4A3)	OTPBE9R1	NR4A3_HUMAN	Decreases Expression	[59]
Interferon-stimulated gene 20 kDa protein (ISG20)	OTCWRJJW	ISG20_HUMAN	Decreases Expression	[59]
Latexin (LXN)	OTZQ2M6Y	LXN_HUMAN	Increases Expression	[59]
Interferon-induced helicase C domain-containing protein 1 (IFIH1)	OTZA2AHA	IFIH1_HUMAN	Decreases Expression	[59]
Anthrax toxin receptor 1 (ANTXR1)	OT5W1GPC	ANTR1_HUMAN	Increases Expression	[59]
Spondin-1 (SPON1)	OTC06MY4	SPON1_HUMAN	Increases Expression	[59]
Interleukin-23 subunit alpha (IL23A)	OTYO99HC	IL23A_HUMAN	Decreases Expression	[59]
Matrix-remodeling-associated protein 5 (MXRA5)	OTXZBWCU	MXRA5_HUMAN	Increases Expression	[59]
NADH dehydrogenase 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2)	OTK0PG7R	NUA4L_HUMAN	Decreases Expression	[59]
Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2)	OT7FCZRM	PP4R2_HUMAN	Increases Expression	[59]
Large neutral amino acids transporter small subunit 2 (SLC7A8)	OT8XXVO8	LAT2_HUMAN	Increases Expression	[59]
Cystine/glutamate transporter (SLC7A11)	OTKJ6PXW	XCT_HUMAN	Decreases Expression	[59]
Hypoxia-inducible lipid droplet-associated protein (HILPDA)	OTEID3ZM	HLPDA_HUMAN	Decreases Expression	[59]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A)	OTBPCU2O	TR10A_HUMAN	Increases Expression	[61]
Claudin-4 (CLDN4)	OT9C4PZ4	CLD4_HUMAN	Increases Expression	[61]
Apoptotic protease-activating factor 1 (APAF1)	OTJWIVY0	APAF_HUMAN	Increases Expression	[61]
Neuropilin-1 (NRP1)	OTCGULYV	NRP1_HUMAN	Increases Expression	[61]
Proepiregulin (EREG)	OTRM4NQY	EREG_HUMAN	Increases Expression	[61]
Myosin regulatory light chain 12B (MYL12B)	OTXMLQOT	ML12B_HUMAN	Increases Expression	[61]
Toll-like receptor 3 (TLR3)	OT8QPYXZ	TLR3_HUMAN	Increases Expression	[61]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Increases Expression	[61]
Semaphorin-7A (SEMA7A)	OT0ZJK64	SEM7A_HUMAN	Increases Expression	[61]
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21)	OT3EDGXO	TNR21_HUMAN	Increases Expression	[61]
Ubiquitin-like protein ATG12 (ATG12)	OTJRO09Y	ATG12_HUMAN	Increases Expression	[61]
Tight junction protein ZO-3 (TJP3)	OTC1K8HC	ZO3_HUMAN	Increases Expression	[61]
Tumor necrosis factor ligand superfamily member 15 (TNFSF15)	OTNGA2BW	TNF15_HUMAN	Increases Expression	[61]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G)	OT8V1J4M	GA45G_HUMAN	Increases Expression	[61]
Claudin-7 (CLDN7)	OTNE0XHQ	CLD7_HUMAN	Increases Expression	[61]
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)	OTBMJUOC	M4K4_HUMAN	Increases Expression	[61]
Claudin-1 (CLDN1)	OT27KV99	CLD1_HUMAN	Increases Expression	[61]
Tissue-type plasminogen activator (PLAT)	OTQPDNAB	TPA_HUMAN	Increases Expression	[61]
Prelamin-A/C (LMNA)	OT3SG7ZR	LMNA_HUMAN	Increases Expression	[61]
Interstitial collagenase (MMP1)	OTI4I2V1	MMP1_HUMAN	Increases Expression	[61]
Platelet-derived growth factor subunit A (PDGFA)	OTCMZ0W8	PDGFA_HUMAN	Increases Expression	[61]
Receptor tyrosine-protein kinase erbB-2 (ERBB2)	OTOAUNCK	ERBB2_HUMAN	Increases Expression	[61]
Integrin beta-2 (ITGB2)	OTEKPEPR	ITB2_HUMAN	Increases Expression	[61]
Endothelin-1 (EDN1)	OTZCACEG	EDN1_HUMAN	Increases Expression	[61]
Intercellular adhesion molecule 1 (ICAM1)	OTTOIX77	ICAM1_HUMAN	Increases Expression	[61]
Cholecystokinin (CCK)	OT1GCG0L	CCKN_HUMAN	Increases Expression	[61]
Gelsolin (GSN)	OT4KS2UU	GELS_HUMAN	Increases Expression	[61]
Cyclin-dependent kinase 1 (CDK1)	OTW1SC2N	CDK1_HUMAN	Decreases Expression	[61]
Glia-derived nexin (SERPINE2)	OTYF5340	GDN_HUMAN	Increases Expression	[61]
Extracellular superoxide dismutase (SOD3)	OTIOZQAB	SODE_HUMAN	Increases Expression	[61]
Matrilysin (MMP7)	OTVT3SEJ	MMP7_HUMAN	Increases Expression	[61]
Clathrin light chain B (CLTB)	OTPW9VRE	CLCB_HUMAN	Increases Expression	[61]
Heme oxygenase 1 (HMOX1)	OTC1W6UX	HMOX1_HUMAN	Increases Expression	[61]
Calmodulin-1 (CALM2)	OTNYA92F	CALM1_HUMAN	Increases Expression	[61]
Ras-related protein R-Ras (RRAS)	OTBBF28C	RRAS_HUMAN	Increases Expression	[61]
Interferon regulatory factor 1 (IRF1)	OT43DI6J	IRF1_HUMAN	Increases Expression	[61]
Cyclin-dependent kinase 4 (CDK4)	OT7EP05T	CDK4_HUMAN	Decreases Expression	[61]
Proliferating cell nuclear antigen (PCNA)	OTHZ1RIA	PCNA_HUMAN	Increases Expression	[61]
Bone morphogenetic protein 1 (BMP1)	OTRFFAL4	BMP1_HUMAN	Increases Expression	[61]
Leukemia inhibitory factor (LIF)	OTO46S5S	LIF_HUMAN	Increases Expression	[61]
Interferon gamma receptor 1 (IFNGR1)	OTCTQBWW	INGR1_HUMAN	Increases Expression	[61]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Increases Expression	[61]
Integrin beta-4 (ITGB4)	OT28UK84	ITB4_HUMAN	Increases Expression	[61]
Beta-galactosidase (GLB1)	OTB0TKAG	BGAL_HUMAN	Increases Expression	[61]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)	OTPGAU0U	AT2A2_HUMAN	Increases Expression	[61]
Amine oxidase A (MAOA)	OT8NIWMQ	AOFA_HUMAN	Increases Expression	[61]
Plasma membrane calcium-transporting ATPase 4 (ATP2B4)	OTMWFDAC	AT2B4_HUMAN	Increases Expression	[61]
G1/S-specific cyclin-D1 (CCND1)	OT8HPTKJ	CCND1_HUMAN	Increases Expression	[61]
Interleukin-4 receptor subunit alpha (IL4R)	OTTXOTCW	IL4RA_HUMAN	Increases Expression	[61]
Insulin-like growth factor-binding protein 6 (IGFBP6)	OTW878VI	IBP6_HUMAN	Increases Expression	[61]
Integrin alpha-3 (ITGA3)	OTBCH21D	ITA3_HUMAN	Increases Expression	[61]
Integrin beta-8 (ITGB8)	OTP4HSHG	ITB8_HUMAN	Increases Expression	[61]
Amine oxidase B (MAOB)	OTTDFM1O	AOFB_HUMAN	Increases Expression	[61]
Proteasome subunit beta type-8 (PSMB8)	OTW5XGMF	PSB8_HUMAN	Increases Expression	[61]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Increases Expression	[61]
G1/S-specific cyclin-D2 (CCND2)	OTDULQF9	CCND2_HUMAN	Increases Expression	[61]
M-phase inducer phosphatase 3 (CDC25C)	OTPQI71S	MPIP3_HUMAN	Decreases Expression	[61]
Leukocyte elastase inhibitor (SERPINB1)	OT5RDUFO	ILEU_HUMAN	Increases Expression	[61]
cAMP-dependent protein kinase type I-beta regulatory subunit (PRKAR1B)	OT777OHS	KAP1_HUMAN	Increases Expression	[61]
RAC-alpha serine/threonine-protein kinase (AKT1)	OT8H2YY7	AKT1_HUMAN	Increases Expression	[61]
Nitric oxide synthase, inducible (NOS2)	OTKKIOJ1	NOS2_HUMAN	Increases Expression	[61]
Metalloproteinase inhibitor 3 (TIMP3)	OTDGQAD1	TIMP3_HUMAN	Increases Expression	[61]
Tumor necrosis factor receptor superfamily member 3 (LTBR)	OT2HVZGV	TNR3_HUMAN	Increases Expression	[61]
Serpin B5 (SERPINB5)	OTSMXQRJ	SPB5_HUMAN	Increases Expression	[61]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Increases Expression	[61]
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2)	OTV232Y7	GPDM_HUMAN	Increases Expression	[61]
Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4)	OTZPZX11	MP2K4_HUMAN	Increases Expression	[61]
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PPP3CC)	OT0AQD93	PP2BC_HUMAN	Increases Expression	[61]
Presenilin-1 (PSEN1)	OTKL39RT	PSN1_HUMAN	Increases Expression	[61]
Matrix metalloproteinase-15 (MMP15)	OT1XF517	MMP15_HUMAN	Increases Expression	[61]
Interleukin-1 receptor-associated kinase 1 (IRAK1)	OT133G8J	IRAK1_HUMAN	Increases Expression	[61]
Cyclin-G1 (CCNG1)	OT17IA9L	CCNG1_HUMAN	Increases Expression	[61]
Caspase-7 (CASP7)	OTAPJ040	CASP7_HUMAN	Increases Expression	[61]
Transforming protein RhoA (RHOA)	OT6YOJ9N	RHOA_HUMAN	Increases Expression	[61]
Interleukin-13 receptor subunit alpha-1 (IL13RA1)	OT59OYXP	I13R1_HUMAN	Increases Expression	[61]
Nuclear factor NF-kappa-B p100 subunit (NFKB2)	OTS231V7	NFKB2_HUMAN	Increases Expression	[61]
E3 ubiquitin-protein ligase Mdm2 (MDM2)	OTOVXARF	MDM2_HUMAN	Increases Expression	[61]
2-oxoglutarate dehydrogenase complex component E1 (OGDH)	OTHGTQWF	ODO1_HUMAN	Increases Expression	[61]
Pro-neuregulin-1, membrane-bound isoform (NRG1)	OTZO6F1X	NRG1_HUMAN	Increases Expression	[61]
Max dimerization protein 1 (MXD1)	OTS5CTHX	MAD1_HUMAN	Increases Expression	[61]
Peroxiredoxin-1 (PRDX1)	OTZ3BEC4	PRDX1_HUMAN	Increases Expression	[61]
Tight junction protein ZO-1 (TJP1)	OTBDCUPK	ZO1_HUMAN	Increases Expression	[61]
Apoptosis regulator BAX (BAX)	OTAW0V4V	BAX_HUMAN	Increases Expression	[61]
Bcl-2-like protein 1 (BCL2L1)	OTRC5K9O	B2CL1_HUMAN	Increases Expression	[61]
Peptidyl-prolyl cis-trans isomerase D (PPID)	OT2CDF7W	PPID_HUMAN	Increases Expression	[61]
Mitogen-activated protein kinase 7 (MAPK7)	OTF7H7L7	MK07_HUMAN	Increases Expression	[61]
Serine/threonine-protein kinase PAK 2 (PAK2)	OTLUNCIH	PAK2_HUMAN	Increases Expression	[61]
Semaphorin-3B (SEMA3B)	OTCZCPMS	SEM3B_HUMAN	Increases Expression	[61]
Baculoviral IAP repeat-containing protein 3 (BIRC3)	OT3E95KB	BIRC3_HUMAN	Increases Expression	[61]
Sequestosome-1 (SQSTM1)	OTGY5D5J	SQSTM_HUMAN	Increases Expression	[61]
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G)	OTHD9KJG	KCC2G_HUMAN	Increases Expression	[61]
Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)	OTJ5XLVU	KCC2D_HUMAN	Increases Expression	[61]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1)	OT6VY3A3	SPTN1_HUMAN	Increases Expression	[61]
Beclin-1 (BECN1)	OT4X293M	BECN1_HUMAN	Increases Expression	[61]
Semaphorin-3A (SEMA3A)	OTQJSV7W	SEM3A_HUMAN	Increases Expression	[61]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3)	OTGQ2AOJ	ITPR3_HUMAN	Increases Expression	[61]
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1)	OTX7MWW1	ITPR1_HUMAN	Increases Expression	[61]
Glutamate receptor ionotropic, NMDA 2C (GRIN2C)	OTV7ZA9O	NMDE3_HUMAN	Increases Expression	[61]
Toll-like receptor 1 (TLR1)	OTZTQIZO	TLR1_HUMAN	Increases Expression	[61]
Mitogen-activated protein kinase 11 (MAPK11)	OT0AS010	MK11_HUMAN	Increases Expression	[61]
Cystatin-M (CST6)	OTZVHJTF	CYTM_HUMAN	Increases Expression	[61]
Bcl-2 homologous antagonist/killer (BAK1)	OTDP6ILW	BAK_HUMAN	Increases Expression	[61]
MHC class I polypeptide-related sequence B (MICB)	OTS2DVDW	MICB_HUMAN	Increases Expression	[61]
Quinone oxidoreductase PIG3 (TP53I3)	OTSCM68G	QORX_HUMAN	Increases Expression	[61]
Autophagy-related protein 16-1 (ATG16L1)	OTEOYC5D	A16L1_HUMAN	Increases Expression	[61]
Cytochrome c oxidase subunit 6B2 (COX6B2)	OT5KU3VV	CX6B2_HUMAN	Increases Expression	[61]
Rho-related GTP-binding protein RhoU (RHOU)	OTERIAD4	RHOU_HUMAN	Increases Expression	[61]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)	OTE8GBUR	RIR2B_HUMAN	Increases Expression	[61]
Cysteine protease ATG4D (ATG4D)	OTSWUO4R	ATG4D_HUMAN	Increases Expression	[61]
TIR domain-containing adapter molecule 1 (TICAM1)	OTK6Y1HK	TCAM1_HUMAN	Increases Expression	[61]
DNA damage-regulated autophagy modulator protein 1 (DRAM1)	OTIJTXEN	DRAM1_HUMAN	Increases Expression	[61]
Interleukin-22 receptor subunit alpha-1 (IL22RA1)	OTGVKLBR	I22R1_HUMAN	Increases Expression	[61]
Protein Atg16l2 (ATG16L2)	OTJYU0W8	A16L2_HUMAN	Increases Expression	[61]
Cysteine protease ATG4A (ATG4A)	OTDHXAPG	ATG4A_HUMAN	Increases Expression	[61]
Histone acetyltransferase KAT2B (KAT2B)	OTWQITWK	KAT2B_HUMAN	Increases Expression	[61]
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25)	OTVZ7I3A	TNR25_HUMAN	Increases Expression	[61]
Tumor protein p53-inducible nuclear protein 1 (TP53INP1)	OT2363Z9	T53I1_HUMAN	Increases Expression	[61]
Claudin-23 (CLDN23)	OTN5RV40	CLD23_HUMAN	Increases Expression	[61]
p53 apoptosis effector related to PMP-22 (PERP)	OTP0YL53	PERP_HUMAN	Increases Expression	[61]
Rho-related GTP-binding protein RhoV (RHOV)	OTW4N3QN	RHOV_HUMAN	Increases Expression	[61]
Mitogen-activated protein kinase kinase kinase 14 (MAP3K14)	OTT3DOOL	M3K14_HUMAN	Increases Expression	[61]
Myeloid differentiation primary response protein MyD88 (MYD88)	OTB4D6FL	MYD88_HUMAN	Increases Expression	[61]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)	OTUYHB84	MLP3B_HUMAN	Increases Expression	[61]
Transient receptor potential cation channel subfamily V member 6 (TRPV6)	OTZ0LGNO	TRPV6_HUMAN	Increases Expression	[61]
p53-induced death domain-containing protein 1 (PIDD1)	OTWFM930	PIDD1_HUMAN	Increases Expression	[61]
Rho-related GTP-binding protein RhoF (RHOF)	OTPA3F8Q	RHOF_HUMAN	Increases Expression	[61]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Increases Expression	[61]
Fructose-2,6-bisphosphatase TIGAR (TIGAR)	OTR7NMRJ	TIGAR_HUMAN	Increases Expression	[61]
Serine/threonine-protein kinase PAK 6 (PAK6)	OTAHPZTT	PAK6_HUMAN	Increases Expression	[61]
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2)	OTPZK76F	TAB2_HUMAN	Increases Expression	[61]
Cingulin (CGN)	OTBCQ8AQ	CING_HUMAN	Increases Expression	[61]
Zinc finger protein PLAGL1 (PLAGL1)	OTZAO900	PLAL1_HUMAN	Increases Expression	[61]
Cytosolic phospholipase A2 gamma (PLA2G4C)	OTIK5GT5	PA24C_HUMAN	Increases Expression	[61]
Cofilin-2 (CFL2)	OTE2W0DH	COF2_HUMAN	Increases Expression	[61]
Complex I intermediate-associated protein 30, mitochondrial (NDUFAF1)	OTYK9JU6	CIA30_HUMAN	Increases Expression	[61]
Talin-2 (TLN2)	OT10QQBC	TLN2_HUMAN	Increases Expression	[61]
Cysteine protease ATG4B (ATG4B)	OTQ4RNRM	ATG4B_HUMAN	Increases Expression	[61]
NF-kappa-B essential modulator (IKBKG)	OTNWJWSD	NEMO_HUMAN	Increases Expression	[61]
S-adenosylmethionine synthase isoform type-2 (MAT2A)	OTFJMIQR	METK2_HUMAN	Decreases Expression	[108]
Serine/threonine-protein kinase Chk1 (CHEK1)	OTTTI622	CHK1_HUMAN	Increases Expression	[109]
Retinoblastoma-associated protein (RB1)	OTQJUJMZ	RB_HUMAN	Increases Phosphorylation	[109]
M-phase inducer phosphatase 1 (CDC25A)	OTSLKKCO	MPIP1_HUMAN	Increases Degradation	[109]
Bifunctional purine biosynthesis protein ATIC (ATIC)	OT8XE052	PUR9_HUMAN	Decreases Expression	[97]
Uncharacterized protein C20orf204 (C20ORF204)	OT0GVQPP	CT204_HUMAN	Decreases Expression	[62]
Uncharacterized protein CXorf51A (CXORF51A)	OTDN5YLP	CX05A_HUMAN	Increases Expression	[62]
Transmembrane protein 120B (TMEM120B)	OTA5XMI9	T120B_HUMAN	Decreases Expression	[62]
Probable ATP-dependent DNA helicase HFM1 (HFM1)	OTHV3EFE	HFM1_HUMAN	Decreases Expression	[62]
Homeobox protein HMX2 (HMX2)	OTBRXY6D	HMX2_HUMAN	Increases Expression	[62]
Protein FAM181B (FAM181B)	OTGZHJ7K	F181B_HUMAN	Decreases Expression	[62]
RNA binding protein fox-1 homolog 3 (RBFOX3)	OTL0F3D6	RFOX3_HUMAN	Decreases Expression	[62]
Protein ANKUB1 (ANKUB1)	OT8QXDL8	ANKUB_HUMAN	Increases Expression	[62]
Olfactory receptor 5H1 (OR5H1)	OT9YQR5A	OR5H1_HUMAN	Increases Expression	[62]
Uncharacterized protein C15orf62, mitochondrial (C15ORF62)	OT2VU9TN	CO062_HUMAN	Increases Expression	[62]
Espin (ESPN)	OT7Z6LX2	ESPN_HUMAN	Increases Expression	[62]
Sperm axonemal maintenance protein CFAP97D1 (CFAP97D1)	OTCPE947	CF97D_HUMAN	Increases Expression	[62]
Putative adrenomedullin-5-like protein (ADM5)	OTFOA92Z	ADM5_HUMAN	Decreases Expression	[62]
Fibronectin type III domain-containing protein 10 (FNDC10)	OT06NW7W	FND10_HUMAN	Decreases Expression	[62]
26S proteasome non-ATPase regulatory subunit 9 (PSMD9)	OT6Y5CC3	PSMD9_HUMAN	Decreases Expression	[62]
Signal-regulatory protein beta-1 (SIRPB1)	OTGHALWJ	SIRB1_HUMAN	Increases Expression	[62]
Basic helix-loop-helix ARNT-like protein 1 (BMAL1)	OTMI12L2	BMAL1_HUMAN	Decreases Expression	[62]
Sulfotransferase 1C2 (SULT1C2)	OT07MMZS	ST1C2_HUMAN	Increases Expression	[62]
C-C chemokine receptor-like 2 (CCRL2)	OT5PX0RX	CCRL2_HUMAN	Decreases Expression	[62]
Synaptotagmin-5 (SYT5)	OT718PRY	SYT5_HUMAN	Decreases Expression	[62]
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (CACNA1A)	OTY08SIX	CAC1A_HUMAN	Increases Expression	[62]
Transcription factor SOX-1 (SOX1)	OTVI1RAR	SOX1_HUMAN	Decreases Expression	[62]
C-X-C chemokine receptor type 6 (CXCR6)	OTK9R50G	CXCR6_HUMAN	Decreases Expression	[62]
Ribonuclease T2 (RNASET2)	OTWY64L7	RNT2_HUMAN	Decreases Expression	[62]
Ficolin-1 (FCN1)	OTK6ZHXH	FCN1_HUMAN	Decreases Expression	[62]
Transcription factor E2F3 (E2F3)	OT5VQMWY	E2F3_HUMAN	Decreases Expression	[62]
Cocaine esterase (CES2)	OTC647SQ	EST2_HUMAN	Decreases Expression	[62]
Suppressor of cytokine signaling 3 (SOCS3)	OTY183WJ	SOCS3_HUMAN	Decreases Expression	[62]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)	OTA1CPBV	TR10B_HUMAN	Decreases Expression	[62]
Gamma-aminobutyric acid receptor subunit delta (GABRD)	OTO38I2R	GBRD_HUMAN	Decreases Expression	[62]
Protein lin-7 homolog A (LIN7A)	OTFL3PUX	LIN7A_HUMAN	Decreases Expression	[62]
Guanine nucleotide exchange factor DBS (MCF2L)	OTEURA8N	MCF2L_HUMAN	Increases Expression	[62]
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C)	OT7DVQB0	RPAC1_HUMAN	Decreases Expression	[62]
Nephrocystin-1 (NPHP1)	OTZHCFFQ	NPHP1_HUMAN	Increases Expression	[62]
Cytoplasmic dynein 1 light intermediate chain 2 (DYNC1LI2)	OTR7WJES	DC1L2_HUMAN	Increases Expression	[62]
U4/U6 small nuclear ribonucleoprotein Prp3 (PRPF3)	OTUA4OLZ	PRPF3_HUMAN	Decreases Expression	[62]
Peptidyl-prolyl cis-trans isomerase H (PPIH)	OTB3HCLB	PPIH_HUMAN	Decreases Expression	[62]
Potassium voltage-gated channel subfamily KQT member 2 (KCNQ2)	OT3CXQJT	KCNQ2_HUMAN	Decreases Expression	[62]
Mothers against decapentaplegic homolog 6 (SMAD6)	OTUZZWUD	SMAD6_HUMAN	Decreases Expression	[62]
Neuronal migration protein doublecortin (DCX)	OTISR7K3	DCX_HUMAN	Increases Expression	[62]
A-kinase anchor protein 7 isoforms alpha and beta (AKAP7)	OT0L3PZ6	AKA7A_HUMAN	Increases Expression	[62]
Peptidase inhibitor 15 (PI15)	OTPJL6ML	PI15_HUMAN	Increases Expression	[62]
Cytohesin-3 (CYTH3)	OTBXAT3Z	CYH3_HUMAN	Increases Expression	[62]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)	OTLVN68B	AAKB2_HUMAN	Increases Expression	[62]
Kalirin (KALRN)	OT8WRCBH	KALRN_HUMAN	Increases Expression	[62]
Protocadherin-7 (PCDH7)	OTP091X8	PCDH7_HUMAN	Increases Expression	[62]
Adenylate cyclase type 3 (ADCY3)	OTGOQM6B	ADCY3_HUMAN	Decreases Expression	[62]
Katanin-interacting protein (KATNIP)	OTLLA1BX	KATIP_HUMAN	Decreases Expression	[62]
Centrosomal protein of 104 kDa (CEP104)	OTOLRJLH	CE104_HUMAN	Increases Expression	[62]
Germinal-center associated nuclear protein (MCM3AP)	OT895FEC	GANP_HUMAN	Increases Expression	[62]
Phospholipid-transporting ATPase IK (ATP8B3)	OTZOGEJO	AT8B3_HUMAN	Decreases Expression	[62]
Ecotropic viral integration site 5 protein homolog (EVI5)	OTOPAP55	EVI5_HUMAN	Increases Expression	[62]
Beta-1,4-galactosyltransferase 3 (B4GALT3)	OTHX77K8	B4GT3_HUMAN	Decreases Expression	[62]
Catenin delta-1 (CTNND1)	OTUMPSHR	CTND1_HUMAN	Decreases Expression	[62]
Dual specificity protein phosphatase CDC14B (CDC14B)	OTAESVOZ	CC14B_HUMAN	Increases Expression	[62]
PRAME family member 11 (PRAMEF11)	OT15BWSL	PRA11_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase TRIM13 (TRIM13)	OTQIUACB	TRI13_HUMAN	Increases Expression	[62]
Short stature homeobox protein 2 (SHOX2)	OTLCZZJW	SHOX2_HUMAN	Increases Expression	[62]
mRNA-capping enzyme (RNGTT)	OT59E0KX	MCE1_HUMAN	Increases Expression	[62]
Calcium-transporting ATPase type 2C member 2 (ATP2C2)	OTGIHTYQ	AT2C2_HUMAN	Decreases Expression	[62]
Transcription initiation protein SPT3 homolog (SUPT3H)	OT7B6FRO	SUPT3_HUMAN	Decreases Expression	[62]
DNA-directed RNA polymerase III subunit RPC9 (CRCP)	OT4K9BT7	RPC9_HUMAN	Decreases Expression	[62]
Decapping and exoribonuclease protein (DXO)	OTFDTNW4	DXO_HUMAN	Decreases Expression	[62]
Pre-mRNA-processing factor 6 (PRPF6)	OT3U0ABN	PRP6_HUMAN	Increases Expression	[62]
Protein furry homolog-like (FRYL)	OTBN3XHN	FRYL_HUMAN	Increases Expression	[62]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Decreases Expression	[62]
Lysine-specific demethylase 4B (KDM4B)	OT5P1UPY	KDM4B_HUMAN	Increases Expression	[62]
Olfactory receptor 2F2 (OR2F2)	OTPYQL7R	OR2F2_HUMAN	Increases Expression	[62]
Olfactory receptor 2A4 (OR2A4)	OT70V8VC	OR2A4_HUMAN	Increases Expression	[62]
Sphingosine 1-phosphate receptor 2 (S1PR2)	OTRTJF29	S1PR2_HUMAN	Increases Expression	[62]
Olfactory receptor 6A2 (OR6A2)	OTWKCMOD	OR6A2_HUMAN	Increases Expression	[62]
Myelin protein zero-like protein 1 (MPZL1)	OTJSUUHR	MPZL1_HUMAN	Increases Expression	[62]
Transforming acidic coiled-coil-containing protein 2 (TACC2)	OTW4M7HI	TACC2_HUMAN	Increases Expression	[62]
Mitogen-activated protein kinase kinase kinase 6 (MAP3K6)	OTOE0Z1R	M3K6_HUMAN	Decreases Expression	[62]
Sodium-dependent phosphate transport protein 2B (SLC34A2)	OTLFMBB0	NPT2B_HUMAN	Decreases Expression	[62]
Claudin-9 (CLDN9)	OTCKI2IZ	CLD9_HUMAN	Decreases Expression	[62]
Neuronal pentraxin receptor (NPTXR)	OTQJEOIH	NPTXR_HUMAN	Increases Expression	[62]
Glucagon-like peptide 2 receptor (GLP2R)	OTVKNDVL	GLP2R_HUMAN	Increases Expression	[62]
Diphosphoinositol polyphosphate phosphohydrolase 1 (NUDT3)	OTXITZUB	NUDT3_HUMAN	Increases Expression	[62]
G1/S-specific cyclin-E2 (CCNE2)	OTBBUKQQ	CCNE2_HUMAN	Decreases Expression	[62]
Coagulation factor XIII A chain (F13A1)	OTO8O184	F13A_HUMAN	Decreases Expression	[62]
Haptoglobin-related protein (HPR)	OTXSC9UB	HPTR_HUMAN	Decreases Expression	[62]
Urokinase-type plasminogen activator (PLAU)	OTX0QGKK	UROK_HUMAN	Decreases Expression	[62]
Protransforming growth factor alpha (TGFA)	OTPD1LL9	TGFA_HUMAN	Decreases Expression	[62]
Interleukin-2 receptor subunit alpha (IL2RA)	OT0MWCHG	IL2RA_HUMAN	Decreases Expression	[62]
Alpha-2-HS-glycoprotein (AHSG)	OTUG0LEA	FETUA_HUMAN	Increases Expression	[62]
Ferritin heavy chain (FTH1)	OT6IFS0O	FRIH_HUMAN	Decreases Expression	[62]
Arginase-1 (ARG1)	OTHZITAM	ARGI1_HUMAN	Increases Expression	[62]
T-cell surface glycoprotein CD1a (CD1A)	OTKSSG6N	CD1A_HUMAN	Decreases Expression	[62]
Prothymosin alpha (PTMA)	OT2W4T1M	PTMA_HUMAN	Decreases Expression	[62]
Thrombomodulin (THBD)	OT8VHLKY	TRBM_HUMAN	Decreases Expression	[62]
Asialoglycoprotein receptor 2 (ASGR2)	OTFSGOVY	ASGR2_HUMAN	Decreases Expression	[62]
Beta-2 adrenergic receptor (ADRB2)	OTSDOX4Q	ADRB2_HUMAN	Increases Expression	[62]
Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)	OT47AK4C	HNRPC_HUMAN	Decreases Expression	[62]
Tumor necrosis factor receptor superfamily member 16 (NGFR)	OTPKSM49	TNR16_HUMAN	Decreases Expression	[62]
Signal recognition particle receptor subunit alpha (SRPRA)	OT5NMYTY	SRPRA_HUMAN	Decreases Expression	[62]
Glutathione S-transferase A1 (GSTA1)	OTA7K5XA	GSTA1_HUMAN	Increases Expression	[62]
Beta-1 adrenergic receptor (ADRB1)	OTQBWN4U	ADRB1_HUMAN	Decreases Expression	[62]
Fibrocystin (PKHD1)	OTAH8SMF	PKHD1_HUMAN	Decreases Expression	[62]
Growth-regulated alpha protein (CXCL1)	OT3WCTZV	GROA_HUMAN	Decreases Expression	[62]
Tumor-associated calcium signal transducer 2 (TACSTD2)	OTLSZR00	TACD2_HUMAN	Decreases Expression	[62]
Protein ELFN1 (ELFN1)	OTM7M52U	ELFN1_HUMAN	Decreases Expression	[62]
Myocardial zonula adherens protein (MYZAP)	OTAZCNBT	MYZAP_HUMAN	Decreases Expression	[62]
A-kinase anchor protein inhibitor 1 (AKAIN1)	OTXO2ZVV	AKAI1_HUMAN	Increases Expression	[62]
Paraneoplastic antigen-like protein 6A (PNMA6A)	OTW96SNS	PNM6A_HUMAN	Increases Expression	[62]
Endothelin-converting enzyme 2 (ECE2)	OTZLNQVL	ECE2_HUMAN	Increases Expression	[62]
Ras-related protein Rap-2a (RAP2A)	OT0JB5S4	RAP2A_HUMAN	Increases Expression	[62]
Transcriptional activator Myb (MYB)	OTJH64IV	MYB_HUMAN	Increases Expression	[62]
60 kDa heat shock protein, mitochondrial (HSPD1)	OTTO1Y11	CH60_HUMAN	Decreases Expression	[62]
Microtubule-associated protein 2 (MAP2)	OT6UYT3X	MTAP2_HUMAN	Increases Expression	[62]
Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)	OTBL2W7R	GTR2_HUMAN	Increases Expression	[62]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)	OT2HZK5M	GTR3_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase pim-1 (PIM1)	OTWEKXTU	PIM1_HUMAN	Decreases Expression	[62]
DNA topoisomerase 1 (TOP1)	OT51O0CF	TOP1_HUMAN	Decreases Expression	[62]
Cytochrome P450 2C9 (CYP2C9)	OTGLBN29	CP2C9_HUMAN	Decreases Expression	[62]
Parathyroid hormone-related protein (PTHLH)	OTI1JF13	PTHR_HUMAN	Increases Expression	[62]
Protein L-Myc (MYCL)	OT1MFQ5U	MYCL_HUMAN	Decreases Expression	[62]
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)	OTU0FC24	COX41_HUMAN	Decreases Expression	[62]
Interferon-induced transmembrane protein 1 (IFITM1)	OTECO1G8	IFM1_HUMAN	Decreases Expression	[62]
HLA class II histocompatibility antigen, DR beta 4 chain (HLA-DRB4)	OTNXIHQU	DRB4_HUMAN	Decreases Expression	[62]
Beta-enolase (ENO3)	OT3HYKYI	ENOB_HUMAN	Increases Expression	[62]
Nidogen-1 (NID1)	OTKLBLS6	NID1_HUMAN	Increases Expression	[62]
Homeobox protein Hox-B3 (HOXB3)	OT9UC5PE	HXB3_HUMAN	Increases Expression	[62]
Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB)	OT3UJ4ZU	RSMB_HUMAN	Decreases Expression	[62]
Cyclic AMP-dependent transcription factor ATF-2 (ATF2)	OTNIZPEA	ATF2_HUMAN	Increases Expression	[62]
Amphiregulin (AREG)	OTJFOR67	AREG_HUMAN	Decreases Expression	[62]
Histone H1.3 (H1-3)	OTT7VPRB	H13_HUMAN	Increases Expression	[62]
Natriuretic peptides B (NPPB)	OTSN2IPY	ANFB_HUMAN	Increases Expression	[62]
Homeobox protein Hox-B8 (HOXB8)	OTKHOD17	HXB8_HUMAN	Decreases Expression	[62]
Homeobox protein Hox-B9 (HOXB9)	OTMVHQOU	HXB9_HUMAN	Increases Expression	[62]
CCAAT/enhancer-binding protein beta (CEBPB)	OTM9MQIA	CEBPB_HUMAN	Decreases Expression	[62]
Complement receptor type 1 (CR1)	OTODWRW4	CR1_HUMAN	Decreases Expression	[62]
Large ribosomal subunit protein eL33 (RPL35A)	OTDDJUWF	RL35A_HUMAN	Increases Expression	[62]
Early growth response protein 1 (EGR1)	OTCP6XGZ	EGR1_HUMAN	Decreases Expression	[62]
Nucleolin (NCL)	OTBXPKMP	NUCL_HUMAN	Decreases Expression	[62]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)	OT2D9DOV	TNR1A_HUMAN	Decreases Expression	[62]
C-X-C motif chemokine 2 (CXCL2)	OTEJCYMY	CXCL2_HUMAN	Decreases Expression	[62]
C-X-C motif chemokine 3 (CXCL3)	OTSL94KH	CXCL3_HUMAN	Decreases Expression	[62]
Tryptase beta-2 (TPSB2)	OTN769MT	TRYB2_HUMAN	Increases Expression	[62]
Interferon-induced GTP-binding protein Mx2 (MX2)	OT05NF37	MX2_HUMAN	Decreases Expression	[62]
B-cell lymphoma 3 protein (BCL3)	OT1M5B95	BCL3_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase MAK (MAK)	OTEU2G41	MAK_HUMAN	Decreases Expression	[62]
Phosphatidylcholine translocator ABCB4 (ABCB4)	OTE6PY83	MDR3_HUMAN	Increases Expression	[62]
Synaptotagmin-1 (SYT1)	OTVTPOI6	SYT1_HUMAN	Increases Expression	[62]
Trifunctional purine biosynthetic protein adenosine-3 (GART)	OT01JWJB	PUR2_HUMAN	Decreases Expression	[62]
Tenascin-X (TNXB)	OTVBWAV5	TENX_HUMAN	Increases Expression	[62]
Acetylcholinesterase (ACHE)	OT2H8HG6	ACES_HUMAN	Increases Expression	[62]
Cytochrome P450 7A1 (CYP7A1)	OT8Z5KLD	CP7A1_HUMAN	Decreases Expression	[62]
Insulin-like growth factor-binding protein 4 (IGFBP4)	OT2HZRBD	IBP4_HUMAN	Decreases Expression	[62]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A)	OTHJQ1DZ	RPB1_HUMAN	Increases Expression	[62]
Signal transducer CD24 (CD24)	OT7CODJ4	CD24_HUMAN	Increases Expression	[62]
Polypyrimidine tract-binding protein 1 (PTBP1)	OT2OBJUK	PTBP1_HUMAN	Decreases Expression	[62]
Aryl hydrocarbon receptor nuclear translocator (ARNT)	OTMSIEZY	ARNT_HUMAN	Decreases Expression	[62]
Grancalcin (GCA)	OTAJ7ZHG	GRAN_HUMAN	Decreases Expression	[62]
Retinoblastoma-like protein 1 (RBL1)	OTDEBFYC	RBL1_HUMAN	Increases Expression	[62]
Nitric oxide synthase 3 (NOS3)	OTLDT7NR	NOS3_HUMAN	Decreases Expression	[62]
Lens fiber major intrinsic protein (MIP)	OTEBLU3E	MIP_HUMAN	Increases Expression	[62]
Homeobox protein Hox-A11 (HOXA11)	OT42C4HF	HXA11_HUMAN	Decreases Expression	[62]
Gamma-aminobutyric acid receptor subunit alpha-5 (GABRA5)	OTBIKWQT	GBRA5_HUMAN	Decreases Expression	[62]
Homeobox protein OTX1 (OTX1)	OTRGSGH9	OTX1_HUMAN	Decreases Expression	[62]
G protein-coupled receptor kinase 4 (GRK4)	OTUU8V2S	GRK4_HUMAN	Increases Expression	[62]
Desmoglein-3 (DSG3)	OTGO4GEY	DSG3_HUMAN	Increases Expression	[62]
Catenin alpha-1 (CTNNA1)	OTFC725Z	CTNA1_HUMAN	Decreases Expression	[62]
Merlin (NF2)	OT6E5ACG	MERL_HUMAN	Decreases Expression	[62]
Mu-type opioid receptor (OPRM1)	OT16AAT8	OPRM_HUMAN	Increases Expression	[62]
Alpha-adducin (ADD1)	OTTF68DC	ADDA_HUMAN	Increases Expression	[62]
RNA-binding protein FUS (FUS)	OTPPNGQO	FUS_HUMAN	Decreases Expression	[62]
Choline kinase alpha (CHKA)	OT7FVO3Z	CHKA_HUMAN	Decreases Expression	[62]
Vitamin K-dependent gamma-carboxylase (GGCX)	OTE0FNAP	VKGC_HUMAN	Decreases Expression	[62]
DNA-binding protein SMUBP-2 (IGHMBP2)	OTAZFPF5	SMBP2_HUMAN	Decreases Expression	[62]
Large ribosomal subunit protein uL3 (RPL3)	OTX6VXLB	RL3_HUMAN	Decreases Expression	[62]
Chymotrypsin-like protease CTRL-1 (CTRL)	OTB6NA5O	CTRL_HUMAN	Decreases Expression	[62]
Pre-B-cell leukemia transcription factor 2 (PBX2)	OTEBYCAW	PBX2_HUMAN	Decreases Expression	[62]
Signal transducer and activator of transcription 3 (STAT3)	OTAAGKYZ	STAT3_HUMAN	Decreases Expression	[62]
Chloride anion exchanger (SLC26A3)	OTBNK2U2	S26A3_HUMAN	Decreases Expression	[62]
Extracellular calcium-sensing receptor (CASR)	OT2PEJDO	CASR_HUMAN	Decreases Expression	[62]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8)	OTOZTA1F	M3K8_HUMAN	Decreases Expression	[62]
C-C chemokine receptor type 2 (CCR2)	OTQ7T10J	CCR2_HUMAN	Decreases Expression	[62]
Signal transducer and activator of transcription 6 (STAT6)	OTCKMP49	STAT6_HUMAN	Decreases Expression	[62]
Caspase-2 (CASP2)	OTUDYSPP	CASP2_HUMAN	Increases Expression	[62]
Neuronal vesicle trafficking-associated protein 1 (NSG1)	OTRIMA50	NSG1_HUMAN	Increases Expression	[62]
Glucagon-like peptide 1 receptor (GLP1R)	OTMB1WEY	GLP1R_HUMAN	Decreases Expression	[62]
ETS translocation variant 4 (ETV4)	OT8C98UZ	ETV4_HUMAN	Increases Expression	[62]
Melanoma-associated antigen 12 (MAGEA12)	OT8ULELL	MAGAC_HUMAN	Increases Expression	[62]
Ran-specific GTPase-activating protein (RANBP1)	OTQE226K	RANG_HUMAN	Decreases Expression	[62]
Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2)	OTX31RLZ	KI2S2_HUMAN	Decreases Expression	[62]
G-protein coupled receptor 4 (GPR4)	OTIBF32I	GPR4_HUMAN	Decreases Expression	[62]
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)	OTI2OREX	MP2K3_HUMAN	Decreases Expression	[62]
Olfactory marker protein (OMP)	OT7JH0DY	OMP_HUMAN	Decreases Expression	[62]
Interferon alpha/beta receptor 2 (IFNAR2)	OTBIRNIJ	INAR2_HUMAN	Decreases Expression	[62]
Serpin B4 (SERPINB4)	OT88LHZ8	SPB4_HUMAN	Increases Expression	[62]
Neuropeptide Y receptor type 2 (NPY2R)	OTEWQJ6B	NPY2R_HUMAN	Decreases Expression	[62]
Melatonin receptor type 1B (MTNR1B)	OT6VFHX9	MTR1B_HUMAN	Increases Expression	[62]
Beta-arrestin-1 (ARRB1)	OT2NJS37	ARRB1_HUMAN	Decreases Expression	[62]
Transmembrane ascorbate-dependent reductase CYB561 (CYB561)	OT61GMNV	CY561_HUMAN	Increases Expression	[62]
Cysteine--tRNA ligase, cytoplasmic (CARS1)	OTOUZF6O	SYCC_HUMAN	Decreases Expression	[62]
Proteasome subunit beta type-2 (PSMB2)	OTX0UG5W	PSB2_HUMAN	Decreases Expression	[62]
Regulator of G-protein signaling 7 (RGS7)	OTDQA90X	RGS7_HUMAN	Increases Expression	[62]
Serpin B9 (SERPINB9)	OTJ811IF	SPB9_HUMAN	Decreases Expression	[62]
Matrix metalloproteinase-16 (MMP16)	OTSFQ2BJ	MMP16_HUMAN	Increases Expression	[62]
Arylsulfatase D (ARSD)	OTAHW9M8	ARSD_HUMAN	Decreases Expression	[62]
Ataxin-1 (ATXN1)	OTQF0HNR	ATX1_HUMAN	Increases Expression	[62]
RNA polymerase II elongation factor ELL (ELL)	OTCBN5LF	ELL_HUMAN	Decreases Expression	[62]
Caspase-9 (CASP9)	OTD4RFFG	CASP9_HUMAN	Decreases Expression	[62]
FAD-linked sulfhydryl oxidase ALR (GFER)	OTVK43OK	ALR_HUMAN	Decreases Expression	[62]
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1)	OT536PE7	SCOT1_HUMAN	Decreases Expression	[62]
Period circadian protein homolog 3 (PER3)	OTVKYVJA	PER3_HUMAN	Increases Expression	[62]
Sestrin-3 (SESN3)	OTJRY1Y5	SESN3_HUMAN	Increases Expression	[62]
Taste receptor type 2 member 50 (TAS2R50)	OTPRMVZW	T2R50_HUMAN	Decreases Expression	[62]
FXYD domain-containing ion transport regulator 4 (FXYD4)	OT06IH3H	FXYD4_HUMAN	Increases Expression	[62]
Eukaryotic initiation factor 4A-I (EIF4A1)	OTMTBX6N	IF4A1_HUMAN	Decreases Expression	[62]
Ras-related protein Rap-2b (RAP2B)	OTD2NDQP	RAP2B_HUMAN	Decreases Expression	[62]
LIM domain transcription factor LMO4 (LMO4)	OT5NDCT9	LMO4_HUMAN	Increases Expression	[62]
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB)	OT24GMCM	PP2AB_HUMAN	Decreases Expression	[62]
Small ribosomal subunit protein eS6 (RPS6)	OTT4D1LN	RS6_HUMAN	Decreases Expression	[62]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Decreases Expression	[62]
Peptidyl-prolyl cis-trans isomerase A (PPIA)	OTHJMWQQ	PPIA_HUMAN	Decreases Expression	[62]
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A)	OT6285L4	FKB1A_HUMAN	Decreases Expression	[62]
Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA)	OT2CEYTT	SHPS1_HUMAN	Increases Expression	[62]
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM8)	OT24S8YN	ADAM8_HUMAN	Decreases Expression	[62]
SRSF protein kinase 2 (SRPK2)	OTFFKMU1	SRPK2_HUMAN	Increases Expression	[62]
UDP-galactose translocator (SLC35A2)	OTQOTOWZ	S35A2_HUMAN	Decreases Expression	[62]
mRNA export factor RAE1 (RAE1)	OT54OKC3	RAE1L_HUMAN	Increases Expression	[62]
Enhancer of rudimentary homolog (ERH)	OTJDWX99	ERH_HUMAN	Decreases Expression	[62]
Histone H3.3 (H3-3B)	OT9XHQ3C	H33_HUMAN	Decreases Expression	[62]
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2)	OT6HTSJT	PGBM_HUMAN	Increases Expression	[62]
Low-density lipoprotein receptor-related protein 2 (LRP2)	OTZ6W681	LRP2_HUMAN	Increases Expression	[62]
Phosphatidylinositol transfer protein alpha isoform (PITPNA)	OTTWC00K	PIPNA_HUMAN	Decreases Expression	[62]
Cyclin-dependent kinase 6 (CDK6)	OTR95N0X	CDK6_HUMAN	Increases Expression	[62]
Forkhead box protein K2 (FOXK2)	OTFXDZ3R	FOXK2_HUMAN	Increases Expression	[62]
High affinity immunoglobulin epsilon receptor subunit beta (MS4A2)	OTMCAS2D	FCERB_HUMAN	Increases Expression	[62]
Interferon-induced transmembrane protein 3 (IFITM3)	OT2QP8D3	IFM3_HUMAN	Decreases Expression	[62]
Interferon-induced transmembrane protein 2 (IFITM2)	OTAT6TI6	IFM2_HUMAN	Decreases Expression	[62]
POU domain, class 4, transcription factor 1 (POU4F1)	OTMHYGWQ	PO4F1_HUMAN	Decreases Expression	[62]
Collagen alpha-3(IV) chain (COL4A3)	OT6SB8X5	CO4A3_HUMAN	Increases Expression	[62]
Amyloid-beta A4 precursor protein-binding family A member 1 (APBA1)	OTUH9JPD	APBA1_HUMAN	Increases Expression	[62]
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4)	OTPV1D60	FKBP4_HUMAN	Decreases Expression	[62]
Mucin-2 (MUC2)	OT3X4QVX	MUC2_HUMAN	Decreases Expression	[62]
cAMP-responsive element modulator (CREM)	OTJIJ5AL	CREM_HUMAN	Decreases Expression	[62]
Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)	OT5WA666	PTN12_HUMAN	Increases Expression	[62]
Early growth response protein 4 (EGR4)	OT4R3ECK	EGR4_HUMAN	Decreases Expression	[62]
Aldehyde oxidase (AOX1)	OT2FZP6H	AOXA_HUMAN	Decreases Expression	[62]
Sulfotransferase 2A1 (SULT2A1)	OT0ISKQ4	ST2A1_HUMAN	Decreases Expression	[62]
Rho GTPase-activating protein 1 (ARHGAP1)	OT0H2ZBZ	RHG01_HUMAN	Increases Expression	[62]
3',5'-cyclic-AMP phosphodiesterase 4C (PDE4C)	OTI8VMHZ	PDE4C_HUMAN	Increases Expression	[62]
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (MGAT5)	OTU4DD4G	MGT5A_HUMAN	Increases Expression	[62]
Uncharacterized protein C17orf67 (C17ORF67)	OTCL5EE8	CQ067_HUMAN	Decreases Expression	[62]
Thyrotroph embryonic factor (TEF)	OTY3LAD9	TEF_HUMAN	Increases Expression	[62]
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3GAL1)	OTFCO8QX	SIA4A_HUMAN	Decreases Expression	[62]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1)	OTNYXOZO	KCMA1_HUMAN	Increases Expression	[62]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1)	OT2LP7LJ	SNF5_HUMAN	Increases Expression	[62]
Glutamate receptor ionotropic, NMDA 2A (GRIN2A)	OTTP0KN8	NMDE1_HUMAN	Increases Expression	[62]
Receptor-type tyrosine-protein phosphatase eta (PTPRJ)	OT10OKOF	PTPRJ_HUMAN	Increases Expression	[62]
Forkhead box protein C1 (FOXC1)	OTOWZGYO	FOXC1_HUMAN	Decreases Expression	[62]
Glutamate receptor ionotropic, kainate 3 (GRIK3)	OTX6K345	GRIK3_HUMAN	Decreases Expression	[62]
Rho GTPase-activating protein 5 (ARHGAP5)	OTOQELUN	RHG05_HUMAN	Increases Expression	[62]
PR domain zinc finger protein 2 (PRDM2)	OT8L7CGX	PRDM2_HUMAN	Decreases Expression	[62]
Lymphocyte cytosolic protein 2 (LCP2)	OT57KE22	LCP2_HUMAN	Decreases Expression	[62]
S-methyl-5'-thioadenosine phosphorylase (MTAP)	OTOWN2K9	MTAP_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase CBL-B (CBLB)	OTPLRER9	CBLB_HUMAN	Decreases Expression	[62]
DNA excision repair protein ERCC-8 (ERCC8)	OT0T4WKI	ERCC8_HUMAN	Increases Expression	[62]
Signaling lymphocytic activation molecule (SLAMF1)	OTBTT3ZQ	SLAF1_HUMAN	Decreases Expression	[62]
Limbic system-associated membrane protein (LSAMP)	OTYXVQX2	LSAMP_HUMAN	Decreases Expression	[62]
GRB2-associated-binding protein 1 (GAB1)	OTQKE6V4	GAB1_HUMAN	Increases Expression	[62]
Histone deacetylase 1 (HDAC1)	OTQDNOXZ	HDAC1_HUMAN	Decreases Expression	[62]
Interferon regulatory factor 5 (IRF5)	OT8SIIAP	IRF5_HUMAN	Increases Expression	[62]
Nucleic acid dioxygenase ALKBH1 (ALKBH1)	OTADGU5D	ALKB1_HUMAN	Affects Expression	[62]
Sodium/potassium-transporting ATPase subunit alpha-4 (ATP1A4)	OT9PLMBH	AT1A4_HUMAN	Increases Expression	[62]
Integrin alpha-9 (ITGA9)	OTHN1IKA	ITA9_HUMAN	Decreases Expression	[62]
Plakophilin-1 (PKP1)	OT9HSQ8F	PKP1_HUMAN	Decreases Expression	[62]
Myelin-associated oligodendrocyte basic protein (MOBP)	OTHJT5CX	MOBP_HUMAN	Decreases Expression	[62]
Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C)	OT6KFNMS	CAC1C_HUMAN	Decreases Expression	[62]
Dihydropyrimidinase-related protein 3 (DPYSL3)	OTINJV20	DPYL3_HUMAN	Increases Expression	[62]
Elongin-A (ELOA)	OTOQTF5K	ELOA1_HUMAN	Increases Expression	[62]
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8)	OT8RPSOC	FKBP8_HUMAN	Decreases Expression	[62]
ATP-dependent RNA helicase DHX8 (DHX8)	OT97S0IH	DHX8_HUMAN	Decreases Expression	[62]
Nuclear receptor coactivator 6 (NCOA6)	OTOMIGTV	NCOA6_HUMAN	Decreases Expression	[62]
Raftlin (RFTN1)	OT8875JE	RFTN1_HUMAN	Increases Expression	[62]
Chromobox protein homolog 2 (CBX2)	OTOQ5WS4	CBX2_HUMAN	Increases Expression	[62]
Nuclear factor 1 X-type (NFIX)	OT1DPZAE	NFIX_HUMAN	Increases Expression	[62]
Importin subunit beta-1 (KPNB1)	OTBT2HFL	IMB1_HUMAN	Increases Expression	[62]
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1)	OT5K42IK	GAPD1_HUMAN	Increases Expression	[62]
MAD2L1-binding protein (MAD2L1BP)	OT2O2IUJ	MD2BP_HUMAN	Decreases Expression	[62]
Rab GTPase-binding effector protein 1 (RABEP1)	OTQROTGT	RABE1_HUMAN	Increases Expression	[62]
SH2 domain-containing adapter protein B (SHB)	OTF2HSC0	SHB_HUMAN	Decreases Expression	[62]
Ficolin-2 (FCN2)	OTTHJBKZ	FCN2_HUMAN	Increases Expression	[62]
Transcription elongation factor A protein 2 (TCEA2)	OT1OS9TY	TCEA2_HUMAN	Increases Expression	[62]
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF2)	OTRHB9SR	NHRF2_HUMAN	Decreases Expression	[62]
Olfactory receptor 1C1 (OR1C1)	OT9WTEX5	OR1C1_HUMAN	Decreases Expression	[62]
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD)	OTBOSJHO	TRADD_HUMAN	Increases Expression	[62]
Tryptase alpha/beta-1 (TPSAB1)	OTJYI4WV	TRYB1_HUMAN	Increases Expression	[62]
Leukotriene B4 receptor 1 (LTB4R)	OT3SRH4H	LT4R1_HUMAN	Decreases Expression	[62]
CCAAT/enhancer-binding protein epsilon (CEBPE)	OTKZA25M	CEBPE_HUMAN	Decreases Expression	[62]
Ras-related protein Rab-30 (RAB30)	OTW49G8B	RAB30_HUMAN	Increases Expression	[62]
Acid-sensing ion channel 2 (ASIC2)	OTIVFS3H	ASIC2_HUMAN	Increases Expression	[62]
Myelin-oligodendrocyte glycoprotein (MOG)	OTYNB7Y5	MOG_HUMAN	Decreases Expression	[62]
Tyrosine-protein phosphatase non-receptor type 21 (PTPN21)	OTQBZWSE	PTN21_HUMAN	Increases Expression	[62]
Dual oxidase maturation factor 2 (DUOXA2)	OT7AZBZJ	DOXA2_HUMAN	Decreases Expression	[62]
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2)	OTJ6JTGT	HNRL2_HUMAN	Increases Expression	[62]
R-spondin-4 (RSPO4)	OTFX5N3G	RSPO4_HUMAN	Decreases Expression	[62]
ATP-binding cassette sub-family B member 5 (ABCB5)	OT8AKP1J	ABCB5_HUMAN	Increases Expression	[62]
Neuroblastoma breakpoint family member 1 (NBPF1)	OTAZ55UQ	NBPF1_HUMAN	Increases Expression	[62]
TBC1 domain family member 25 (TBC1D25)	OT11OABF	TBC25_HUMAN	Decreases Expression	[62]
Transmembrane protein 176B (TMEM176B)	OTEGF2BV	T176B_HUMAN	Decreases Expression	[62]
C2 domain-containing protein 3 (C2CD3)	OTC52E7V	C2CD3_HUMAN	Increases Expression	[62]
tRNA-queuosine alpha-mannosyltransferase (GTDC1)	OT8OBXKK	QTMAN_HUMAN	Increases Expression	[62]
Coiled-coil domain-containing protein 152 (CCDC152)	OTJQTQXC	CC152_HUMAN	Increases Expression	[62]
Coiled-coil domain-containing protein 40 (CCDC40)	OTFHEUUN	CCD40_HUMAN	Decreases Expression	[62]
Minichromosome maintenance domain-containing protein 2 (MCMDC2)	OTTG0EQU	MCMD2_HUMAN	Decreases Expression	[62]
Synaptotagmin-like protein 3 (SYTL3)	OT6TPBA9	SYTL3_HUMAN	Increases Expression	[62]
Protein lin-52 homolog (LIN52)	OT14OQ1C	LIN52_HUMAN	Increases Expression	[62]
Seizure protein 6 homolog (SEZ6)	OTCD8K5D	SEZ6_HUMAN	Decreases Expression	[62]
Transmembrane 4 L6 family member 20 (TM4SF20)	OTNXU9QW	T4S20_HUMAN	Decreases Expression	[62]
HCLS1-binding protein 3 (HS1BP3)	OT5NSZJ1	H1BP3_HUMAN	Decreases Expression	[62]
Germinal center-associated signaling and motility-like protein (GCSAML)	OTYWDOA6	GSAML_HUMAN	Increases Expression	[62]
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 (SOHLH1)	OT3RBLSK	SOLH1_HUMAN	Decreases Expression	[62]
Intracellular hyaluronan-binding protein 4 (HABP4)	OTU223PA	HABP4_HUMAN	Increases Expression	[62]
Coiled-coil domain-containing protein 158 (CCDC158)	OTT3RXZN	CD158_HUMAN	Decreases Expression	[62]
RNA-binding protein 26 (RBM26)	OTG4C53Y	RBM26_HUMAN	Decreases Expression	[62]
Roquin-1 (RC3H1)	OTCU6CYA	RC3H1_HUMAN	Decreases Expression	[62]
Radial spoke head protein 4 homolog A (RSPH4A)	OTNDPGEE	RSH4A_HUMAN	Decreases Expression	[62]
Four and a half LIM domains protein 5 (FHL5)	OT6C00Z1	FHL5_HUMAN	Decreases Expression	[62]
Protein PRR14L (PRR14L)	OT290EDE	PR14L_HUMAN	Increases Expression	[62]
Centrosome-associated protein 350 (CEP350)	OT5Q3AEA	CE350_HUMAN	Increases Expression	[62]
Divergent protein kinase domain 1B (DIPK1B)	OTSPU5O5	DIK1B_HUMAN	Increases Expression	[62]
OTU domain-containing protein 1 (OTUD1)	OTE6O5XB	OTUD1_HUMAN	Decreases Expression	[62]
DDB1- and CUL4-associated factor 12-like protein 2 (DCAF12L2)	OTLEF5TY	DC122_HUMAN	Increases Expression	[62]
Interleukin-23 receptor (IL23R)	OTT6L7U8	IL23R_HUMAN	Decreases Expression	[62]
Muscular LMNA-interacting protein (MLIP)	OTMT7AII	MLIP_HUMAN	Increases Expression	[62]
Ankyrin repeat domain-containing protein 34A (ANKRD34A)	OTI00ROL	AN34A_HUMAN	Decreases Expression	[62]
Multiple C2 and transmembrane domain-containing protein 2 (MCTP2)	OTFMZ8I2	MCTP2_HUMAN	Decreases Expression	[62]
General transcription factor II-I repeat domain-containing protein 2B (GTF2IRD2B)	OTO0L3A2	GTD2B_HUMAN	Increases Expression	[62]
Tyrosine-protein kinase STYK1 (STYK1)	OT61CSU7	STYK1_HUMAN	Decreases Expression	[62]
Kelch-like protein 10 (KLHL10)	OTB41MP9	KLH10_HUMAN	Increases Expression	[62]
Proline-rich protein 5-like (PRR5L)	OTQ1Z0OU	PRR5L_HUMAN	Decreases Expression	[62]
RPA-related protein RADX (RADX)	OTKV8BMJ	RADX_HUMAN	Increases Expression	[62]
Glutamate-rich protein 5 (ERICH5)	OTQEY1SQ	ERIC5_HUMAN	Increases Expression	[62]
Ankyrin repeat domain-containing protein 16 (ANKRD16)	OTZD4JUO	ANR16_HUMAN	Decreases Expression	[62]
MTOR-associated protein MEAK7 (MEAK7)	OT9A8JSO	MEAK7_HUMAN	Decreases Expression	[62]
E3 ubiquitin-protein ligase RFWD3 (RFWD3)	OTDUULBQ	RFWD3_HUMAN	Decreases Expression	[62]
F-box only protein 38 (FBXO38)	OTSZ3768	FBX38_HUMAN	Decreases Expression	[62]
Consortin (CNST)	OTOUCB98	CNST_HUMAN	Increases Expression	[62]
Docking protein 6 (DOK6)	OTX55OIF	DOK6_HUMAN	Increases Expression	[62]
Type-1 angiotensin II receptor-associated protein (AGTRAP)	OT02N7LD	ATRAP_HUMAN	Decreases Expression	[62]
Coiled-coil domain-containing protein 171 (CCDC171)	OT9NL2D9	CC171_HUMAN	Increases Expression	[62]
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (MTHFD1L)	OTV01EFP	C1TM_HUMAN	Increases Expression	[62]
Transmembrane protein 107 (TMEM107)	OT9RMLBJ	TM107_HUMAN	Decreases Expression	[62]
C-type lectin domain family 4 member G (CLEC4G)	OTUGTR0H	CLC4G_HUMAN	Decreases Expression	[62]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (TPTE2)	OTR3K733	TPTE2_HUMAN	Increases Expression	[62]
Sulfhydryl oxidase 2 (QSOX2)	OTMLKYFP	QSOX2_HUMAN	Decreases Expression	[62]
Patched domain-containing protein 4 (PTCHD4)	OTGJ8NRP	PTHD4_HUMAN	Increases Expression	[62]
Cyclic AMP-responsive element-binding protein 3-like protein 2 (CREB3L2)	OT09MHV0	CR3L2_HUMAN	Increases Expression	[62]
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (PREX2)	OTYT1J6J	PREX2_HUMAN	Decreases Expression	[62]
Protein FRA10AC1 (FRA10AC1)	OT730MMV	F10C1_HUMAN	Increases Expression	[62]
Mediator of RNA polymerase II transcription subunit 13-like (MED13L)	OTSP1W0F	MD13L_HUMAN	Increases Expression	[62]
Immunoglobulin-like domain-containing receptor 2 (ILDR2)	OTNNK3VC	ILDR2_HUMAN	Increases Expression	[62]
GRB2-associated and regulator of MAPK protein 2 (GAREM2)	OTQNQAC7	GARE2_HUMAN	Increases Expression	[62]
Carbohydrate sulfotransferase 15 (CHST15)	OTNTM2SP	CHSTF_HUMAN	Decreases Expression	[62]
STE20-related kinase adapter protein alpha (STRADA)	OTG1Z6TY	STRAA_HUMAN	Decreases Expression	[62]
#NAME?	OTD229X7	MICA3_HUMAN	Increases Expression	[62]
Aprataxin (APTX)	OTPAS5G8	APTX_HUMAN	Decreases Expression	[62]
Endoplasmic reticulum metallopeptidase 1 (ERMP1)	OT9CIEO2	ERMP1_HUMAN	Decreases Expression	[62]
Nucleoporin p54 (NUP54)	OTHOIRMG	NUP54_HUMAN	Decreases Expression	[62]
Keratin, type I cytoskeletal 25 (KRT25)	OT4JMRN6	K1C25_HUMAN	Increases Expression	[62]
Transmembrane channel-like protein 6 (TMC6)	OTKH50J4	TMC6_HUMAN	Decreases Expression	[62]
Cytoplasmic polyadenylation element-binding protein 2 (CPEB2)	OTKES4YR	CPEB2_HUMAN	Decreases Expression	[62]
FERM domain-containing protein 5 (FRMD5)	OTC73XJK	FRMD5_HUMAN	Increases Expression	[62]
Beta-defensin 132 (DEFB132)	OT5SRTW1	DB132_HUMAN	Increases Expression	[62]
Cytokine-dependent hematopoietic cell linker (CLNK)	OTOWK51S	CLNK_HUMAN	Decreases Expression	[62]
Protein polybromo-1 (PBRM1)	OT39WUR9	PB1_HUMAN	Increases Expression	[62]
CUB and zona pellucida-like domain-containing protein 1 (CUZD1)	OTDQJVZ8	CUZD1_HUMAN	Increases Expression	[62]
Organic solute transporter subunit alpha (SLC51A)	OTDJRZ0P	OSTA_HUMAN	Increases Expression	[62]
Zinc finger protein castor homolog 1 (CASZ1)	OTWJ2OR8	CASZ1_HUMAN	Increases Expression	[62]
Liprin-beta-1 (PPFIBP1)	OTRA2S7B	LIPB1_HUMAN	Increases Expression	[62]
Fibrocystin-L (PKHD1L1)	OTREFCAA	PKHL1_HUMAN	Increases Expression	[62]
Protein NLRC5 (NLRC5)	OTY8X6MC	NLRC5_HUMAN	Decreases Expression	[62]
Vasculin (GPBP1)	OTUXR2GD	GPBP1_HUMAN	Increases Expression	[62]
Ral GTPase-activating protein subunit beta (RALGAPB)	OTY8CGA3	RLGPB_HUMAN	Increases Expression	[62]
Diacylglycerol kinase eta (DGKH)	OTYNPJ4B	DGKH_HUMAN	Decreases Expression	[62]
Probable guanine nucleotide exchange factor MCF2L2 (MCF2L2)	OTOGFMIH	MF2L2_HUMAN	Decreases Expression	[62]
Ras-related protein Rab-43 (RAB43)	OTVCSILI	RAB43_HUMAN	Decreases Expression	[62]
NudC domain-containing protein 3 (NUDCD3)	OT2WYBNC	NUDC3_HUMAN	Decreases Expression	[62]
Somatomedin-B and thrombospondin type-1 domain-containing protein (SBSPON)	OTBHAW5K	SBSPO_HUMAN	Increases Expression	[62]
Kinase suppressor of Ras 1 (KSR1)	OT9GUVLI	KSR1_HUMAN	Decreases Expression	[62]
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 (NKAIN4)	OT91HOEP	NKAI4_HUMAN	Decreases Expression	[62]
Sphingosine-1-phosphate transporter SPNS2 (SPNS2)	OTPODAPU	SPNS2_HUMAN	Decreases Expression	[62]
FAD-dependent oxidoreductase domain-containing protein 2 (FOXRED2)	OTSJOZ3O	FXRD2_HUMAN	Decreases Expression	[62]
PHD finger protein 6 (PHF6)	OT8DXI40	PHF6_HUMAN	Increases Expression	[62]
Calcium homeostasis endoplasmic reticulum protein (CHERP)	OTJL4OB3	CHERP_HUMAN	Decreases Expression	[62]
GTP-binding protein REM 2 (REM2)	OT0RTOI8	REM2_HUMAN	Decreases Expression	[62]
Cilia- and flagella-associated protein 46 (CFAP46)	OTRZZHB9	CFA46_HUMAN	Increases Expression	[62]
Rhotekin-2 (RTKN2)	OTV2AXQM	RTKN2_HUMAN	Increases Expression	[62]
Heparan-sulfate 6-O-sulfotransferase 3 (HS6ST3)	OTTW9PDL	H6ST3_HUMAN	Decreases Expression	[62]
Leucine-rich repeat LGI family member 3 (LGI3)	OT0CZ85H	LGI3_HUMAN	Increases Expression	[62]
Protein SYS1 homolog (SYS1)	OTTVS1LN	SYS1_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase pellino homolog 3 (PELI3)	OTCBUSKJ	PELI3_HUMAN	Increases Expression	[62]
Protein FAM43A (FAM43A)	OT5RPQRE	FA43A_HUMAN	Increases Expression	[62]
Leucine-rich repeat-containing protein 25 (LRRC25)	OTCKAZA5	LRC25_HUMAN	Decreases Expression	[62]
Chemokine-like protein TAFA-2 (TAFA2)	OTU6WP6J	TAFA2_HUMAN	Decreases Expression	[62]
Follistatin-related protein 5 (FSTL5)	OT18C29S	FSTL5_HUMAN	Increases Expression	[62]
Kinesin-like protein KIF2B (KIF2B)	OTLPAX4N	KIF2B_HUMAN	Increases Expression	[62]
T-complex protein 11-like protein 2 (TCP11L2)	OTTIZO7B	T11L2_HUMAN	Increases Expression	[62]
Prolyl 3-hydroxylase OGFOD1 (OGFOD1)	OTTUQ5O3	OGFD1_HUMAN	Increases Expression	[62]
Ceramide synthase 5 (CERS5)	OT5A2DNI	CERS5_HUMAN	Increases Expression	[62]
Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3)	OTBNQCOS	LIRA3_HUMAN	Decreases Expression	[62]
IQ domain-containing protein F1 (IQCF1)	OTXFEQ37	IQCF1_HUMAN	Decreases Expression	[62]
Stress-associated endoplasmic reticulum protein 2 (SERP2)	OT5GA6JZ	SERP2_HUMAN	Increases Expression	[62]
Leucine-rich repeat-containing protein 17 (LRRC17)	OT3NZSX3	LRC17_HUMAN	Increases Expression	[62]
ER membrane protein complex subunit 1 (EMC1)	OTYAH4LX	EMC1_HUMAN	Decreases Expression	[62]
Androglobin (ADGB)	OT1TM9DT	ADGB_HUMAN	Decreases Expression	[62]
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (ANKRD44)	OTUI0WOO	ANR44_HUMAN	Decreases Expression	[62]
Coiled-coil domain-containing protein 71L (CCDC71L)	OT7ECVUW	CC71L_HUMAN	Decreases Expression	[62]
Tetratricopeptide repeat protein 29 (TTC29)	OT37KCUL	TTC29_HUMAN	Increases Expression	[62]
Fanconi anemia group B protein (FANCB)	OTMZTXB5	FANCB_HUMAN	Increases Expression	[62]
Hemicentin-2 (HMCN2)	OTJK9CGG	HMCN2_HUMAN	Increases Expression	[62]
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3)	OTLUM9L7	PK3C3_HUMAN	Increases Expression	[62]
Microcephalin (MCPH1)	OTYT3TT5	MCPH1_HUMAN	Increases Expression	[62]
Methylcytosine dioxygenase TET1 (TET1)	OTZDHT1D	TET1_HUMAN	Increases Expression	[62]
Telomere repeats-binding bouquet formation protein 2 (TERB2)	OTUJDOF8	TERB2_HUMAN	Increases Expression	[62]
Checkpoint protein HUS1B (HUS1B)	OT3VFQWS	HUS1B_HUMAN	Decreases Expression	[62]
Stomatin-like protein 3 (STOML3)	OTLQGALK	STML3_HUMAN	Increases Expression	[62]
Protein odd-skipped-related 1 (OSR1)	OTB19LEQ	OSR1_HUMAN	Increases Expression	[62]
Ras and Rab interactor 3 (RIN3)	OT5Z6F8O	RIN3_HUMAN	Decreases Expression	[62]
Piwi-like protein 2 (PIWIL2)	OT1PXQIF	PIWL2_HUMAN	Decreases Expression	[62]
Glutamate receptor ionotropic, NMDA 3A (GRIN3A)	OTQS9GYY	NMD3A_HUMAN	Increases Expression	[62]
Mirror-image polydactyly gene 1 protein (MIPOL1)	OTLPN3D0	MIPO1_HUMAN	Increases Expression	[62]
Chromodomain-helicase-DNA-binding protein 6 (CHD6)	OTEHW1U2	CHD6_HUMAN	Increases Expression	[62]
Protocadherin Fat 3 (FAT3)	OT3C6H8W	FAT3_HUMAN	Decreases Expression	[62]
GPI ethanolamine phosphate transferase 3 (PIGO)	OTGDOBO1	PIGO_HUMAN	Decreases Expression	[62]
Guanine nucleotide exchange protein SMCR8 (SMCR8)	OT52BQH4	SMCR8_HUMAN	Decreases Expression	[62]
Partitioning defective 3 homolog B (PARD3B)	OTGZ43YI	PAR3L_HUMAN	Increases Expression	[62]
SH3 domain and tetratricopeptide repeat-containing protein 2 (SH3TC2)	OTJ6XY2A	S3TC2_HUMAN	Increases Expression	[62]
F-box only protein 41 (FBXO41)	OT5MC4TZ	FBX41_HUMAN	Increases Expression	[62]
Protein prune homolog 2 (PRUNE2)	OTGW2974	PRUN2_HUMAN	Increases Expression	[62]
Protein POF1B (POF1B)	OTFWNK8G	POF1B_HUMAN	Decreases Expression	[62]
GTPase IMAP family member 1 (GIMAP1)	OT7AJ1TT	GIMA1_HUMAN	Decreases Expression	[62]
Palladin (PALLD)	OTZ2MUJZ	PALLD_HUMAN	Increases Expression	[62]
RUN and FYVE domain-containing protein 2 (RUFY2)	OTT9C6SM	RUFY2_HUMAN	Increases Expression	[62]
Stonin-2 (STON2)	OT01JHHE	STON2_HUMAN	Increases Expression	[62]
Connector enhancer of kinase suppressor of ras 2 (CNKSR2)	OTAGERJ2	CNKR2_HUMAN	Increases Expression	[62]
Voltage-dependent calcium channel gamma-8 subunit (CACNG8)	OTP6227G	CCG8_HUMAN	Increases Expression	[62]
Cationic amino acid transporter 3 (SLC7A3)	OTKEFAHV	CTR3_HUMAN	Decreases Expression	[62]
Transmembrane O-methyltransferase (LRTOMT)	OTMLESUJ	TOMT_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase rififylin (RFFL)	OT85MGDH	RFFL_HUMAN	Increases Expression	[62]
Alpha-2,8-sialyltransferase 8B (ST8SIA2)	OTRBBBD8	SIA8B_HUMAN	Increases Expression	[62]
Sorting nexin-19 (SNX19)	OTGNS3HG	SNX19_HUMAN	Increases Expression	[62]
Transmembrane protein 131 (TMEM131)	OT72FBLT	TM131_HUMAN	Decreases Expression	[62]
Stalled ribosome sensor GCN1 (GCN1)	OTBFVD7Z	GCN1_HUMAN	Decreases Expression	[62]
Centromere protein I (CENPI)	OTWRIMZ3	CENPI_HUMAN	Decreases Expression	[62]
Caspase-10 (CASP10)	OTE6J88E	CASPA_HUMAN	Decreases Expression	[62]
Phosphatidate cytidylyltransferase 1 (CDS1)	OT2F591M	CDS1_HUMAN	Increases Expression	[62]
Endonuclease 8-like 2 (NEIL2)	OTV6JEON	NEIL2_HUMAN	Decreases Expression	[62]
Polyamine deacetylase HDAC10 (HDAC10)	OTHCKKUQ	HDA10_HUMAN	Decreases Expression	[62]
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1)	OT351FKB	ERGI1_HUMAN	Increases Expression	[62]
Autophagy-related protein 2 homolog B (ATG2B)	OT7FGFJ1	ATG2B_HUMAN	Decreases Expression	[62]
Pyrroline-5-carboxylate reductase 2 (PYCR2)	OTS2HLGD	P5CR2_HUMAN	Decreases Expression	[62]
FAS-associated factor 2 (FAF2)	OTE8CE2E	FAF2_HUMAN	Increases Expression	[62]
RalBP1-associated Eps domain-containing protein 1 (REPS1)	OTX4ERRK	REPS1_HUMAN	Increases Expression	[62]
U8 snoRNA-decapping enzyme (NUDT16)	OTWSL9JQ	NUD16_HUMAN	Decreases Expression	[62]
THAP domain-containing protein 11 (THAP11)	OTEMWLZ0	THA11_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase CHFR (CHFR)	OTRAD2TT	CHFR_HUMAN	Decreases Expression	[62]
Small integral membrane protein 12 (SMIM12)	OTMOQSL4	SIM12_HUMAN	Decreases Expression	[62]
UDP-N-acetylglucosamine transferase subunit ALG14 homolog (ALG14)	OTBM7K28	ALG14_HUMAN	Increases Expression	[62]
OTU domain-containing protein 5 (OTUD5)	OTMCR6JM	OTUD5_HUMAN	Decreases Expression	[62]
Solute carrier family 25 member 44 (SLC25A44)	OTHHPC3C	S2544_HUMAN	Decreases Expression	[62]
Dedicator of cytokinesis protein 6 (DOCK6)	OTPNUVLT	DOCK6_HUMAN	Increases Expression	[62]
Kin of IRRE-like protein 1 (KIRREL1)	OTOA7ON7	KIRR1_HUMAN	Increases Expression	[62]
Spatacsin (SPG11)	OTZ7LJX4	SPTCS_HUMAN	Affects Expression	[62]
Protein SPMIP9 (SPMIP9)	OT66UEFP	SMIP9_HUMAN	Decreases Expression	[62]
Coiled-coil domain-containing protein 7 (CCDC7)	OTNCL9JR	CCDC7_HUMAN	Increases Expression	[62]
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)	OT5TS6P7	PCMD1_HUMAN	Increases Expression	[62]
Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST2)	OT8A3H9Y	H6ST2_HUMAN	Increases Expression	[62]
Transmembrane protein 74 (TMEM74)	OT3IZBM0	TMM74_HUMAN	Increases Expression	[62]
2-oxoglutarate receptor 1 (OXGR1)	OT2D4V93	OXGR1_HUMAN	Increases Expression	[62]
N-acetylneuraminate 9-O-acetyltransferase (CASD1)	OT1YB54Z	CASD1_HUMAN	Decreases Expression	[62]
AP-1 complex subunit sigma-3 (AP1S3)	OTPCMV24	AP1S3_HUMAN	Increases Expression	[62]
BTB/POZ domain-containing protein 9 (BTBD9)	OTWQ6GA3	BTBD9_HUMAN	Decreases Expression	[62]
Rho GTPase-activating protein 7 (DLC1)	OTP8LMCR	RHG07_HUMAN	Increases Expression	[62]
Sorting nexin-18 (SNX18)	OT68KT3X	SNX18_HUMAN	Increases Expression	[62]
Tribbles homolog 1 (TRIB1)	OTPEO17G	TRIB1_HUMAN	Decreases Expression	[62]
Ras-related protein Rab-40C (RAB40C)	OTM2V2R0	RB40C_HUMAN	Increases Expression	[62]
Protein ABHD1 (ABHD1)	OTY56U02	ABHD1_HUMAN	Decreases Expression	[62]
CDK5 regulatory subunit-associated protein 2 (CDK5RAP2)	OTRKEVTY	CK5P2_HUMAN	Increases Expression	[62]
Insulinoma-associated protein 2 (INSM2)	OTNMQUZV	INSM2_HUMAN	Increases Expression	[62]
Glutamate decarboxylase 1 (GAD1)	OT52Z39J	DCE1_HUMAN	Decreases Expression	[62]
M-phase phosphoprotein 6 (MPHOSPH6)	OT6E2S48	MPH6_HUMAN	Decreases Expression	[62]
Max-binding protein MNT (MNT)	OTPC4ANL	MNT_HUMAN	Decreases Expression	[62]
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A)	OTVFRL8G	TI17A_HUMAN	Decreases Expression	[62]
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB)	OTUKPFOK	ROAA_HUMAN	Decreases Expression	[62]
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF)	OTT5JX1F	LITAF_HUMAN	Decreases Expression	[62]
Noelin (OLFM1)	OTOYPEWW	NOE1_HUMAN	Decreases Expression	[62]
Spindlin-2A (SPIN2A)	OT93VTU4	SPI2A_HUMAN	Increases Expression	[62]
Histone H2B type 1-M (H2BC14)	OTSDZZZY	H2B1M_HUMAN	Decreases Expression	[62]
Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B)	OTT2ZGSR	ATF6B_HUMAN	Increases Expression	[62]
Tyrosine-protein phosphatase non-receptor type 18 (PTPN18)	OT0S09B3	PTN18_HUMAN	Decreases Expression	[62]
F-box-like/WD repeat-containing protein TBL1Y (TBL1Y)	OTA0F7TM	TBL1Y_HUMAN	Decreases Expression	[62]
Serine/threonine-protein phosphatase CPPED1 (CPPED1)	OT88U8X5	CPPED_HUMAN	Decreases Expression	[62]
Suppressor of IKBKE 1 (SIKE1)	OT5O11J0	SIKE1_HUMAN	Increases Expression	[62]
Mitochondrial nucleoid-associated protein 1 (MTNAP1)	OT8FB2F8	CQ080_HUMAN	Increases Expression	[62]
Trichoplein keratin filament-binding protein (TCHP)	OTVDMHSY	TCHP_HUMAN	Decreases Expression	[62]
Immediate early response gene 2 protein (IER2)	OT5OY8BO	IER2_HUMAN	Decreases Expression	[62]
Protein misato homolog 1 (MSTO1)	OT37XCNP	MSTO1_HUMAN	Decreases Expression	[62]
PHD finger protein 23 (PHF23)	OTVF5VZC	PHF23_HUMAN	Decreases Expression	[62]
Specifically androgen-regulated gene protein (C1ORF116)	OTPYEXDM	SARG_HUMAN	Increases Expression	[62]
DET1- and DDB1-associated protein 1 (DDA1)	OTAZIAIH	DDA1_HUMAN	Increases Expression	[62]
GTP-binding protein 2 (GTPBP2)	OTOJ1KUA	GTPB2_HUMAN	Increases Expression	[62]
Protein LSM14 homolog B (LSM14B)	OTW646HP	LS14B_HUMAN	Increases Expression	[62]
Transient receptor potential cation channel subfamily M member 6 (TRPM6)	OTW7SPUV	TRPM6_HUMAN	Decreases Expression	[62]
Protein amnionless (AMN)	OTS1TJXG	AMNLS_HUMAN	Decreases Expression	[62]
Complement factor H-related protein 5 (CFHR5)	OT7BMOYE	FHR5_HUMAN	Decreases Expression	[62]
Testis-expressed protein 12 (TEX12)	OTXHQWTA	TEX12_HUMAN	Decreases Expression	[62]
Calcium-binding protein 8 (CALN1)	OTN2XE4T	CABP8_HUMAN	Increases Expression	[62]
Cell adhesion molecule 1 (CADM1)	OTRWG9QS	CADM1_HUMAN	Increases Expression	[62]
Polymerase delta-interacting protein 3 (POLDIP3)	OTTB5SV7	PDIP3_HUMAN	Increases Expression	[62]
Large ribosomal subunit protein uL4m (MRPL4)	OT8AE74Y	RM04_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase 33 (STK33)	OT98KLEL	STK33_HUMAN	Increases Expression	[62]
FERM domain-containing protein 8 (FRMD8)	OTTH5DUJ	FRMD8_HUMAN	Decreases Expression	[62]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Decreases Expression	[62]
Group XIIA secretory phospholipase A2 (PLA2G12A)	OTHHCQ17	PG12A_HUMAN	Increases Expression	[62]
Testicular spindle-associated protein SHCBP1L (SHCBP1L)	OTYGG089	SHP1L_HUMAN	Decreases Expression	[62]
GREB1-like protein (GREB1L)	OTZTY5KQ	GRB1L_HUMAN	Increases Expression	[62]
E3 ubiquitin-protein ligase makorin-2 (MKRN2)	OTDD1V3O	MKRN2_HUMAN	Increases Expression	[62]
Large subunit GTPase 1 homolog (LSG1)	OTDAXJ9L	LSG1_HUMAN	Decreases Expression	[62]
NUAK family SNF1-like kinase 2 (NUAK2)	OTUEZLO8	NUAK2_HUMAN	Decreases Expression	[62]
Oxysterol-binding protein-related protein 5 (OSBPL5)	OTI1UJXT	OSBL5_HUMAN	Decreases Expression	[62]
Nucleoporin-62 C-terminal-like protein (NUP62CL)	OTEN1HET	N62CL_HUMAN	Increases Expression	[62]
Oxysterol-binding protein-related protein 2 (OSBPL2)	OTCK671N	OSBL2_HUMAN	Decreases Expression	[62]
Ciliary microtubule inner protein 1 (CIMIP1)	OTKOYVKF	CMIP1_HUMAN	Increases Expression	[62]
Mediator of RNA polymerase II transcription subunit 28 (MED28)	OTEDM1L5	MED28_HUMAN	Decreases Expression	[62]
EH domain-containing protein 4 (EHD4)	OT7G5JTT	EHD4_HUMAN	Decreases Expression	[62]
Translation initiation factor IF-3, mitochondrial (MTIF3)	OTPQ7FPQ	IF3M_HUMAN	Increases Expression	[62]
Kallikrein-15 (KLK15)	OT7BVG17	KLK15_HUMAN	Decreases Expression	[62]
Chordin (CHRD)	OTNM60Y1	CHRD_HUMAN	Decreases Expression	[62]
Sorting nexin-25 (SNX25)	OT8JY8M1	SNX25_HUMAN	Increases Expression	[62]
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10)	OT5HFZXU	BACD3_HUMAN	Decreases Expression	[62]
Histamine H4 receptor (HRH4)	OTBJO49O	HRH4_HUMAN	Decreases Expression	[62]
Leucine-rich repeat neuronal protein 3 (LRRN3)	OT7X0AA7	LRRN3_HUMAN	Increases Expression	[62]
Cystatin-9-like (CST9L)	OT7GBIWW	CST9L_HUMAN	Increases Expression	[62]
Cilia- and flagella-associated protein 68 (CFAP68)	OTG4EK2P	CFA68_HUMAN	Decreases Expression	[62]
tRNA (NSUN3)	OTLBKU22	NSUN3_HUMAN	Decreases Expression	[62]
DENN domain-containing protein 2D (DENND2D)	OTXEFJWM	DEN2D_HUMAN	Decreases Expression	[62]
HAUS augmin-like complex subunit 4 (HAUS4)	OTFIO49N	HAUS4_HUMAN	Decreases Expression	[62]
PDZ domain-containing protein MAGIX (MAGIX)	OT8EU651	MAGIX_HUMAN	Increases Expression	[62]
Tudor domain-containing protein 3 (TDRD3)	OTG83E2C	TDRD3_HUMAN	Increases Expression	[62]
Nuclear exosome regulator NRDE2 (NRDE2)	OTJ1V33O	NRDE2_HUMAN	Increases Expression	[62]
Proton-activated chloride channel (PACC1)	OTKBS8CC	PACC1_HUMAN	Increases Expression	[62]
Jupiter microtubule associated homolog 2 (JPT2)	OTJGPA4T	JUPI2_HUMAN	Increases Expression	[62]
Akirin-1 (AKIRIN1)	OTINWTT9	AKIR1_HUMAN	Decreases Expression	[62]
DNA-directed RNA polymerase I subunit RPA2 (POLR1B)	OTKREU8M	RPA2_HUMAN	Decreases Expression	[62]
Pleckstrin homology domain-containing family A member 5 (PLEKHA5)	OT2MNW8T	PKHA5_HUMAN	Increases Expression	[62]
Claspin (CLSPN)	OTZZXNDK	CLSPN_HUMAN	Increases Expression	[62]
Dual specificity protein kinase CLK4 (CLK4)	OTD38YJI	CLK4_HUMAN	Increases Expression	[62]
Sp110 nuclear body protein (SP110)	OTFW6WH7	SP110_HUMAN	Decreases Expression	[62]
POZ-, AT hook-, and zinc finger-containing protein 1 (PATZ1)	OT0X9WGR	PATZ1_HUMAN	Decreases Expression	[62]
Interleukin-21 receptor (IL21R)	OTDIOB63	IL21R_HUMAN	Decreases Expression	[62]
UPF0606 protein KIAA1549 (KIAA1549)	OTA5B18F	K1549_HUMAN	Increases Expression	[62]
CD209 antigen (CD209)	OTCAX8NI	CD209_HUMAN	Decreases Expression	[62]
3',5'-cyclic-AMP phosphodiesterase 7B (PDE7B)	OTK3SHT2	PDE7B_HUMAN	Increases Expression	[62]
Potassium channel subfamily K member 9 (KCNK9)	OT8P734M	KCNK9_HUMAN	Decreases Expression	[62]
Frizzled-3 (FZD3)	OTIWDN78	FZD3_HUMAN	Increases Expression	[62]
Odorant-binding protein 2b (OBP2B)	OTVKMIM4	OBP2B_HUMAN	Increases Expression	[62]
Proline-rich nuclear receptor coactivator 2 (PNRC2)	OTE7W7Y5	PNRC2_HUMAN	Increases Expression	[62]
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 (B3GAT2)	OTNSM9XP	B3GA2_HUMAN	Decreases Expression	[62]
Anoctamin-2 (ANO2)	OT650E98	ANO2_HUMAN	Decreases Expression	[62]
Mitochondrial dynamics protein MIEF1 (MIEF1)	OTFSP3FS	MID51_HUMAN	Decreases Expression	[62]
Scavenger receptor cysteine-rich type 1 protein M160 (CD163L1)	OTZHN1XQ	C163B_HUMAN	Decreases Expression	[62]
Matrix metalloproteinase-26 (MMP26)	OT9O89KU	MMP26_HUMAN	Decreases Expression	[62]
Teashirt homolog 2 (TSHZ2)	OTZWBXXY	TSH2_HUMAN	Increases Expression	[62]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)	OTWHOVZS	BAZ1A_HUMAN	Decreases Expression	[62]
CDC42 small effector protein 1 (CDC42SE1)	OTV3MRFE	C42S1_HUMAN	Decreases Expression	[62]
Cysteinyl leukotriene receptor 2 (CYSLTR2)	OTRNEOZ0	CLTR2_HUMAN	Decreases Expression	[62]
LanC-like protein 2 (LANCL2)	OT7KWGMR	LANC2_HUMAN	Decreases Expression	[62]
Cytokine-inducible SH2-containing protein (CISH)	OT8T5NYL	CISH_HUMAN	Decreases Expression	[62]
GPI mannosyltransferase 2 (PIGV)	OTI6LT46	PIGV_HUMAN	Increases Expression	[62]
Probable ATP-dependent RNA helicase DDX28 (DDX28)	OTIIHNYN	DDX28_HUMAN	Decreases Expression	[62]
SPATS2-like protein (SPATS2L)	OTFO07H8	SPS2L_HUMAN	Increases Expression	[62]
DNA-directed RNA polymerase III subunit RPC5 (POLR3E)	OT69PWBM	RPC5_HUMAN	Decreases Expression	[62]
Arginine and glutamate-rich protein 1 (ARGLU1)	OTRVRZ4Z	ARGL1_HUMAN	Increases Expression	[62]
Protein FAM118A (FAM118A)	OT6EM97E	F118A_HUMAN	Decreases Expression	[62]
Ankyrin repeat and SOCS box protein 6 (ASB6)	OTFAJPSF	ASB6_HUMAN	Decreases Expression	[62]
Ras-related protein Rab-20 (RAB20)	OTP9OOVS	RAB20_HUMAN	Decreases Expression	[62]
Pre-mRNA-splicing factor CWC25 homolog (CWC25)	OT96LFJH	CWC25_HUMAN	Decreases Expression	[62]
Stabilin-1 (STAB1)	OTW2HMCE	STAB1_HUMAN	Decreases Expression	[62]
Gamma-2-syntrophin (SNTG2)	OTD8HJCD	SNTG2_HUMAN	Decreases Expression	[62]
Cyclin-dependent kinase 12 (CDK12)	OTZUDGNU	CDK12_HUMAN	Decreases Expression	[62]
Placenta-specific gene 8 protein (PLAC8)	OT3SYRUJ	PLAC8_HUMAN	Decreases Expression	[62]
Opioid growth factor receptor (OGFR)	OTROS6RJ	OGFR_HUMAN	Decreases Expression	[62]
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22)	OT452ZDC	ADA22_HUMAN	Increases Expression	[62]
SLAIN motif-containing protein 2 (SLAIN2)	OTSM5QIO	SLAI2_HUMAN	Increases Expression	[62]
RNA-binding protein 27 (RBM27)	OTBVP6VJ	RBM27_HUMAN	Increases Expression	[62]
Arginine-glutamic acid dipeptide repeats protein (RERE)	OT3G4GBZ	RERE_HUMAN	Increases Expression	[62]
Cardiotrophin-like cytokine factor 1 (CLCF1)	OTHQUDDI	CLCF1_HUMAN	Decreases Expression	[62]
Cornulin (CRNN)	OTAORBR4	CRNN_HUMAN	Increases Expression	[62]
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD)	OTP9COQT	PISD_HUMAN	Decreases Expression	[62]
ATP-binding cassette sub-family F member 2 (ABCF2)	OTXIBZ3N	ABCF2_HUMAN	Decreases Expression	[62]
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2)	OTHTAM54	AAKG2_HUMAN	Decreases Expression	[62]
Poly polymerase 2 (PARP2)	OTYL81ZI	PARP2_HUMAN	Increases Expression	[62]
LIM domain-containing protein 1 (LIMD1)	OTN1CG6R	LIMD1_HUMAN	Decreases Expression	[62]
Armadillo repeat-containing X-linked protein 3 (ARMCX3)	OTMG7RWW	ARMX3_HUMAN	Increases Expression	[62]
Max-like protein X (MLX)	OTZ74KFI	MLX_HUMAN	Decreases Expression	[62]
NPC1-like intracellular cholesterol transporter 1 (NPC1L1)	OT6GWW1P	NPCL1_HUMAN	Increases Expression	[62]
Adhesion G protein-coupled receptor E2 (ADGRE2)	OTUYJVYG	AGRE2_HUMAN	Decreases Expression	[62]
Dimethylglycine dehydrogenase, mitochondrial (DMGDH)	OTPJEWQ8	M2GD_HUMAN	Increases Expression	[62]
Importin-11 (IPO11)	OTG19WN0	IPO11_HUMAN	Decreases Expression	[62]
Methyl-CpG-binding domain protein 1 (MBD1)	OTD19VO6	MBD1_HUMAN	Increases Expression	[62]
Adherens junction-associated protein 1 (AJAP1)	OTAAW121	AJAP1_HUMAN	Decreases Expression	[62]
Zinc finger protein Helios (IKZF2)	OTZIMARJ	IKZF2_HUMAN	Increases Expression	[62]
Nuclear pore complex protein Nup50 (NUP50)	OTOZ98K3	NUP50_HUMAN	Decreases Expression	[62]
Transcription factor-like 5 protein (TCFL5)	OTJL4348	TCFL5_HUMAN	Decreases Expression	[62]
Malignant T-cell-amplified sequence 1 (MCTS1)	OT7SAOJP	MCTS1_HUMAN	Increases Expression	[62]
Signal-transducing adaptor protein 1 (STAP1)	OTUTZH0W	STAP1_HUMAN	Increases Expression	[62]
Hippocalcin-like protein 4 (HPCAL4)	OT793RNP	HPCL4_HUMAN	Decreases Expression	[62]
Ornithine decarboxylase antizyme 3 (OAZ3)	OT8Q5PVB	OAZ3_HUMAN	Increases Expression	[62]
Protocadherin gamma-C3 (PCDHGC3)	OTDXTUMI	PCDGK_HUMAN	Increases Expression	[62]
Rab effector Noc2 (RPH3AL)	OT9VFJEL	RPH3L_HUMAN	Increases Expression	[62]
Trinucleotide repeat-containing gene 6B protein (TNRC6B)	OTGVT0SH	TNR6B_HUMAN	Increases Expression	[62]
Protein Smaug homolog 1 (SAMD4A)	OT4MKCC8	SMAG1_HUMAN	Increases Expression	[62]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)	OTEU05TX	PPR3C_HUMAN	Increases Expression	[62]
Solute carrier family 22 member 13 (SLC22A13)	OTM96T5U	S22AD_HUMAN	Increases Expression	[62]
Nucleotide-binding oligomerization domain-containing protein 1 (NOD1)	OTUN9GUS	NOD1_HUMAN	Decreases Expression	[62]
Inversin (INVS)	OT8KPESR	INVS_HUMAN	Increases Expression	[62]
F-box/WD repeat-containing protein 1A (BTRC)	OT2EZDGR	FBW1A_HUMAN	Increases Expression	[62]
Sodium/hydrogen exchanger 8 (SLC9A8)	OTR56QTT	SL9A8_HUMAN	Decreases Expression	[62]
Protein strawberry notch homolog 2 (SBNO2)	OT1C6J3K	SBNO2_HUMAN	Decreases Expression	[62]
Serine/threonine-protein kinase SIK3 (SIK3)	OTH0V1L5	SIK3_HUMAN	Decreases Expression	[62]
Hypoxia-inducible factor 3-alpha (HIF3A)	OTPWAAMC	HIF3A_HUMAN	Decreases Expression	[62]
Long-chain fatty acid transport protein 6 (SLC27A6)	OT2AJU6L	S27A6_HUMAN	Increases Expression	[62]
G-protein coupled receptor 55 (GPR55)	OTUSATXO	GPR55_HUMAN	Decreases Expression	[62]
RNA-binding motif protein, X-linked 2 (RBMX2)	OTGGU7N1	RBMX2_HUMAN	Decreases Expression	[62]
Nucleolar complex protein 2 homolog (NOC2L)	OTNT7R33	NOC2L_HUMAN	Decreases Expression	[62]
DDB1- and CUL4-associated factor 1 (DCAF1)	OT3ZDVOE	DCAF1_HUMAN	Decreases Expression	[62]
Meiosis regulator and mRNA stability factor 1 (MARF1)	OTYRJ4V2	MARF1_HUMAN	Increases Expression	[62]
Lysyl oxidase homolog 2 (LOXL2)	OTRT46B5	LOXL2_HUMAN	Increases Expression	[62]
Cyanocobalamin reductase / alkylcobalamin dealkylase (MMACHC)	OTX0TT3W	MMAC_HUMAN	Increases Expression	[62]
Protocadherin gamma-A9 (PCDHGA9)	OTKJE2H2	PCDG9_HUMAN	Increases Expression	[62]
Protocadherin gamma-A3 (PCDHGA3)	OTTOGYJA	PCDG3_HUMAN	Decreases Expression	[62]
Doublesex- and mab-3-related transcription factor 1 (DMRT1)	OT5PU9U1	DMRT1_HUMAN	Decreases Expression	[62]
RNA-binding protein 8A (RBM8A)	OT5SR6G0	RBM8A_HUMAN	Decreases Expression	[62]
Solute carrier family 12 member 7 (SLC12A7)	OT29GM25	S12A7_HUMAN	Decreases Expression	[62]
Gap junction alpha-3 protein (GJA3)	OTXV6ETF	CXA3_HUMAN	Increases Expression	[62]
Peroxisomal membrane protein 4 (PXMP4)	OTNDYSHU	PXMP4_HUMAN	Increases Expression	[62]
Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1)	OTSPVITK	STYL1_HUMAN	Decreases Expression	[62]
DNA (DNMT3A)	OTEJP0GH	DNM3A_HUMAN	Increases Expression	[62]
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)	OT4ZSEEE	IF2B2_HUMAN	Increases Expression	[62]
Transcription factor E2F8 (E2F8)	OTQKZGFP	E2F8_HUMAN	Decreases Expression	[63]
Class E basic helix-loop-helix protein 40 (BHLHE40)	OTITX14U	BHE40_HUMAN	Increases Expression	[63]
Citron Rho-interacting kinase (CIT)	OTOZDKPG	CTRO_HUMAN	Decreases Expression	[63]
Kinetochore protein NDC80 homolog (NDC80)	OTS7D306	NDC80_HUMAN	Decreases Expression	[63]
Aurora kinase A (AURKA)	OTMX0HYT	AURKA_HUMAN	Decreases Expression	[63]
Protein Mis18-beta (OIP5)	OTI5C2DE	MS18B_HUMAN	Decreases Expression	[63]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)	OT80DZMT	BUB1_HUMAN	Decreases Expression	[63]
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3)	OTX1C2GS	DYRK3_HUMAN	Increases Expression	[63]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)	OT8KME51	BUB1B_HUMAN	Decreases Expression	[63]
Hyaluronan mediated motility receptor (HMMR)	OT4M0JTZ	HMMR_HUMAN	Decreases Expression	[63]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)	OTYG179K	PR15A_HUMAN	Increases Expression	[63]
G2/mitotic-specific cyclin-B2 (CCNB2)	OTIEXTDK	CCNB2_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIF20A (KIF20A)	OTXOQHE0	KI20A_HUMAN	Decreases Expression	[63]
Chromosome-associated kinesin KIF4A (KIF4A)	OT3UWL7D	KIF4A_HUMAN	Decreases Expression	[63]
Integrin beta-like protein 1 (ITGBL1)	OTJDHE17	ITGBL_HUMAN	Decreases Expression	[63]
Aldehyde dehydrogenase 1A1 (ALDH1A1)	OTCUWZKB	AL1A1_HUMAN	Decreases Expression	[63]
DNA topoisomerase 2-alpha (TOP2A)	OT6LPS08	TOP2A_HUMAN	Decreases Expression	[63]
G2/mitotic-specific cyclin-B1 (CCNB1)	OT19S7E5	CCNB1_HUMAN	Decreases Expression	[63]
Histone H1.5 (H1-5)	OTAN7RD9	H15_HUMAN	Decreases Expression	[63]
Cyclin-A2 (CCNA2)	OTPHHYZJ	CCNA2_HUMAN	Decreases Expression	[63]
Lamin-B1 (LMNB1)	OT100T3P	LMNB1_HUMAN	Decreases Expression	[63]
Interleukin-11 (IL11)	OTXHN86R	IL11_HUMAN	Increases Expression	[63]
Diamine acetyltransferase 1 (SAT1)	OT52AU22	SAT1_HUMAN	Increases Expression	[63]
Arylacetamide deacetylase (AADAC)	OT8VACT2	AAAD_HUMAN	Increases Expression	[63]
GTP cyclohydrolase 1 (GCH1)	OTOZ6NSL	GCH1_HUMAN	Increases Expression	[63]
Ribonucleoside-diphosphate reductase subunit M2 (RRM2)	OTOB6J6R	RIR2_HUMAN	Decreases Expression	[63]
Histone H2B type 1-B (H2BC3)	OT1BLFJO	H2B1B_HUMAN	Decreases Expression	[63]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Increases Expression	[63]
Proliferation marker protein Ki-67 (MKI67)	OTA8N1QI	KI67_HUMAN	Decreases Expression	[63]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Decreases Expression	[63]
DNA primase small subunit (PRIM1)	OTWWP8Y6	PRI1_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIF11 (KIF11)	OTHRGLCQ	KIF11_HUMAN	Decreases Expression	[63]
Serine/threonine-protein kinase PLK1 (PLK1)	OTRZX45T	PLK1_HUMAN	Decreases Expression	[63]
DNA polymerase epsilon subunit 2 (POLE2)	OTAC9V6L	DPOE2_HUMAN	Decreases Expression	[63]
Sestrin-2 (SESN2)	OT889IXY	SESN2_HUMAN	Increases Expression	[63]
Rho-related GTP-binding protein RhoE (RND3)	OTXMXPIH	RND3_HUMAN	Increases Expression	[63]
Histone H3.1 (H3C1)	OTGBGOZW	H31_HUMAN	Decreases Expression	[63]
Arginase-2, mitochondrial (ARG2)	OTCPI0E8	ARGI2_HUMAN	Increases Expression	[63]
G-protein-signaling modulator 2 (GPSM2)	OT6RPMRM	GPSM2_HUMAN	Decreases Expression	[63]
55 kDa erythrocyte membrane protein (MPP1)	OTA2ENZQ	EM55_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIF23 (KIF23)	OTY850JC	KIF23_HUMAN	Decreases Expression	[63]
Forkhead box protein M1 (FOXM1)	OT5887KR	FOXM1_HUMAN	Decreases Expression	[63]
Magnesium transporter NIPA4 (NIPAL4)	OT43JC9A	NIPA4_HUMAN	Increases Expression	[63]
Cell division cycle protein 20 homolog (CDC20)	OTCOEZRV	CDC20_HUMAN	Decreases Expression	[63]
TNF receptor-associated factor 1 (TRAF1)	OTTLM5RU	TRAF1_HUMAN	Increases Expression	[63]
S-phase kinase-associated protein 2 (SKP2)	OTD5B41X	SKP2_HUMAN	Decreases Expression	[63]
DNA replication licensing factor MCM6 (MCM6)	OTKLIAWT	MCM6_HUMAN	Decreases Expression	[63]
Maternal embryonic leucine zipper kinase (MELK)	OTEY2UQA	MELK_HUMAN	Decreases Expression	[63]
Condensin complex subunit 2 (NCAPH)	OTXOS97C	CND2_HUMAN	Decreases Expression	[63]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Decreases Expression	[63]
Disks large-associated protein 5 (DLGAP5)	OTWCN39U	DLGP5_HUMAN	Decreases Expression	[63]
Nuclear factor interleukin-3-regulated protein (NFIL3)	OTQH9HM3	NFIL3_HUMAN	Increases Expression	[63]
Cyclin-dependent kinase inhibitor 3 (CDKN3)	OTBE3H07	CDKN3_HUMAN	Decreases Expression	[63]
DNA excision repair protein ERCC-6-like (ERCC6L)	OTE9V7D9	ERC6L_HUMAN	Decreases Expression	[63]
Borealin (CDCA8)	OT17D55D	BOREA_HUMAN	Decreases Expression	[63]
Shugoshin 2 (SGO2)	OTNGJDS8	SGO2_HUMAN	Decreases Expression	[63]
Fidgetin (FIGN)	OTJF6EZR	FIGN_HUMAN	Decreases Expression	[63]
RRP12-like protein (RRP12)	OTQQAEH4	RRP12_HUMAN	Increases Expression	[63]
Alkaline ceramidase 2 (ACER2)	OTS3DDE5	ACER2_HUMAN	Increases Expression	[63]
DEP domain-containing protein 1A (DEPDC1)	OT0JWE1B	DEP1A_HUMAN	Decreases Expression	[63]
Rho GTPase-activating protein 11A (ARHGAP11A)	OTVQCFVP	RHGBA_HUMAN	Decreases Expression	[63]
Transmembrane protein 71 (TMEM71)	OTA7W26O	TMM71_HUMAN	Decreases Expression	[63]
Serine protease FAM111B (FAM111B)	OT9IQ9NV	F111B_HUMAN	Decreases Expression	[63]
Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1)	OTO4UIDB	CCBE1_HUMAN	Decreases Expression	[63]
Lysine-specific demethylase 7A (KDM7A)	OT1VGYCX	KDM7A_HUMAN	Increases Expression	[63]
Alkylglycerol monooxygenase (AGMO)	OTGMAHAT	ALKMO_HUMAN	Decreases Expression	[63]
Condensin-2 complex subunit G2 (NCAPG2)	OTZYENKO	CNDG2_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIF18B (KIF18B)	OTOBUDOE	KI18B_HUMAN	Decreases Expression	[63]
Abnormal spindle-like microcephaly-associated protein (ASPM)	OTKXQMNA	ASPM_HUMAN	Decreases Expression	[63]
Kinetochore protein Spc24 (SPC24)	OT1HVYV4	SPC24_HUMAN	Decreases Expression	[63]
Meiosis-specific nuclear structural protein 1 (MNS1)	OT67F3JQ	MNS1_HUMAN	Decreases Expression	[63]
SHC SH2 domain-binding protein 1 (SHCBP1)	OT3A21CM	SHCBP_HUMAN	Decreases Expression	[63]
Kelch repeat and BTB domain-containing protein 8 (KBTBD8)	OTO8X1UF	KBTB8_HUMAN	Increases Expression	[63]
Kinetochore scaffold 1 (KNL1)	OT4Q3LHV	KNL1_HUMAN	Decreases Expression	[63]
Endonuclease 8-like 3 (NEIL3)	OTBCI2NS	NEIL3_HUMAN	Decreases Expression	[63]
Enkurin (ENKUR)	OTXXBBQT	ENKUR_HUMAN	Increases Expression	[63]
Transcription initiation factor TFIID subunit 4B (TAF4B)	OTCICY31	TAF4B_HUMAN	Increases Expression	[63]
Histone H2B type 1-H (H2BC9)	OTQ9XX72	H2B1H_HUMAN	Decreases Expression	[63]
Proline-rich protein 11 (PRR11)	OT2JJ08Z	PRR11_HUMAN	Decreases Expression	[63]
Lymphokine-activated killer T-cell-originated protein kinase (PBK)	OT5Z27TW	TOPK_HUMAN	Decreases Expression	[63]
Guanine nucleotide exchange factor C9orf72 (C9ORF72)	OT0WH38E	CI072_HUMAN	Increases Expression	[63]
Sperm-associated antigen 5 (SPAG5)	OTCLJ56M	SPAG5_HUMAN	Decreases Expression	[63]
Centromere protein K (CENPK)	OTKPUF8K	CENPK_HUMAN	Decreases Expression	[63]
Transmembrane protein 106C (TMEM106C)	OTDOD9OQ	T106C_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIFC1 (KIFC1)	OTNQDS00	KIFC1_HUMAN	Decreases Expression	[63]
Fanconi anemia group J protein (BRIP1)	OT38QBD4	FANCJ_HUMAN	Decreases Expression	[63]
Nucleolar and spindle-associated protein 1 (NUSAP1)	OT85HIJ5	NUSAP_HUMAN	Decreases Expression	[63]
Fanconi anemia group D2 protein (FANCD2)	OTVEB5LF	FACD2_HUMAN	Decreases Expression	[63]
Kinetochore protein Nuf2 (NUF2)	OTOOQL35	NUF2_HUMAN	Decreases Expression	[63]
Ankyrin repeat family A protein 2 (ANKRA2)	OTLSLV5A	ANRA2_HUMAN	Increases Expression	[63]
Kinetochore protein Spc25 (SPC25)	OTCAS0OH	SPC25_HUMAN	Decreases Expression	[63]
Anillin (ANLN)	OTXJY54C	ANLN_HUMAN	Decreases Expression	[63]
Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7)	OT3QER33	ENTP7_HUMAN	Increases Expression	[63]
Phospholipid scramblase 4 (PLSCR4)	OT2AMYLY	PLS4_HUMAN	Decreases Expression	[63]
Kinesin-like protein KIF15 (KIF15)	OTJRJEXL	KIF15_HUMAN	Decreases Expression	[63]
Histone chaperone ASF1B (ASF1B)	OTKXX12I	ASF1B_HUMAN	Decreases Expression	[63]
GTPase IMAP family member 2 (GIMAP2)	OTHH2EFT	GIMA2_HUMAN	Decreases Expression	[63]
Kelch-like protein 21 (KLHL21)	OT28Y2LQ	KLH21_HUMAN	Increases Expression	[63]
DNA replication complex GINS protein PSF2 (GINS2)	OT974IYI	PSF2_HUMAN	Decreases Expression	[63]
E3 ubiquitin-protein ligase RNF114 (RNF114)	OTF06FRP	RN114_HUMAN	Increases Expression	[63]
POTE ankyrin domain family member F (POTEF)	OTV3WXYE	POTEF_HUMAN	Decreases Expression	[64]
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10)	OTBURQ3A	NDUAA_HUMAN	Increases Expression	[64]
Fructose-bisphosphate aldolase A (ALDOA)	OTWRFTIB	ALDOA_HUMAN	Decreases Expression	[64]
Keratin, type I cytoskeletal 18 (KRT18)	OTVLQFIP	K1C18_HUMAN	Increases Expression	[64]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Decreases Expression	[64]
Alpha-enolase (ENO1)	OTB1KWJS	ENOA_HUMAN	Increases Expression	[64]
Nucleophosmin (NPM1)	OTTBYYT0	NPM_HUMAN	Increases Expression	[64]
Phosphoglycerate mutase 1 (PGAM1)	OTZ5DB06	PGAM1_HUMAN	Decreases Expression	[64]
Proteasome subunit alpha type-2 (PSMA2)	OTJRT2ZL	PSA2_HUMAN	Decreases Expression	[64]
Endoplasmic reticulum resident protein 29 (ERP29)	OTNKANMH	ERP29_HUMAN	Decreases Expression	[64]
Triosephosphate isomerase (TPI1)	OT14KP4B	TPIS_HUMAN	Decreases Expression	[64]
Poly(rC)-binding protein 1 (PCBP1)	OTHN0TD7	PCBP1_HUMAN	Decreases Expression	[64]
Fascin (FSCN1)	OTTGIHTM	FSCN1_HUMAN	Decreases Expression	[64]
Lambda-crystallin homolog (CRYL1)	OT0SJSJM	CRYL1_HUMAN	Increases Expression	[64]
NF-kappa-B inhibitor epsilon (NFKBIE)	OTLAYEL9	IKBE_HUMAN	Decreases Expression	[110]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Secretion	[111]
Importin subunit alpha-4 (KPNA3)	OTLI3TM2	IMA4_HUMAN	Decreases Expression	[112]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11)	OTJEPKEQ	TNF11_HUMAN	Decreases Expression	[111]
Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C)	OTVHOL9B	TR10C_HUMAN	Increases Expression	[110]
Angiopoietin-2 (ANGPT2)	OTEQK65P	ANGP2_HUMAN	Increases Expression	[66]
Protein SLC31A2 (SLC31A2)	OTQC136Q	COPT2_HUMAN	Increases Expression	[113]
CASP8 and FADD-like apoptosis regulator (CFLAR)	OTX14BAS	CFLAR_HUMAN	Increases Expression	[110]
Mitogen-activated protein kinase kinase kinase 7 (MAP3K7)	OTUXEASC	M3K7_HUMAN	Decreases Expression	[112]
Tumor necrosis factor ligand superfamily member 14 (TNFSF14)	OT5QRF09	TNF14_HUMAN	Increases Expression	[114]
Protein regulator of cytokinesis 1 (PRC1)	OTHD0XS0	PRC1_HUMAN	Decreases Expression	[65]
Integral membrane protein 2A (ITM2A)	OT590V63	ITM2A_HUMAN	Increases Expression	[69]
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3)	OTUG02U7	KHDR3_HUMAN	Increases Expression	[69]
Dual specificity protein phosphatase 14 (DUSP14)	OTGODFCR	DUS14_HUMAN	Increases Expression	[113]
CCN family member 4 (CCN4)	OT69BER9	CCN4_HUMAN	Decreases Expression	[67]
Superoxide dismutase (SOD1)	OT39TA1L	SODC_HUMAN	Increases Expression	[115]
Cystatin-A (CSTA)	OT1K68KE	CYTA_HUMAN	Increases Expression	[69]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Increases Expression	[116]
Vasopressin-neurophysin 2-copeptin (AVP)	OTAVZ76K	NEU2_HUMAN	Increases Secretion	[117]
Tumor necrosis factor (TNF)	OT4IE164	TNFA_HUMAN	Increases Expression	[115]
Interleukin-1 beta (IL1B)	OT0DWXXB	IL1B_HUMAN	Increases Expression	[69]
T-cell surface glycoprotein CD4 (CD4)	OT7Z5LNF	CD4_HUMAN	Decreases Expression	[118]
T-cell surface glycoprotein CD8 alpha chain (CD8A)	OTDWQJXK	CD8A_HUMAN	Decreases Expression	[118]
Collagen alpha-1(I) chain (COL1A1)	OTI31178	CO1A1_HUMAN	Decreases Expression	[69]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Decreases Secretion	[119]
Heat shock protein beta-1 (HSPB1)	OTHFZ8ED	HSPB1_HUMAN	Increases Expression	[113]
Plasminogen activator inhibitor 1 (SERPINE1)	OTT0MPQ3	PAI1_HUMAN	Increases Expression	[120]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Phosphorylation	[121]
Integrin beta-1 (ITGB1)	OT6G1IAR	ITB1_HUMAN	Decreases Expression	[112]
Glutathione peroxidase 1 (GPX1)	OTE2O72Q	GPX1_HUMAN	Increases Expression	[122]
Complement decay-accelerating factor (CD55)	OTZ3HWTO	DAF_HUMAN	Increases Expression	[68]
Stromelysin-1 (MMP3)	OTGBI74Z	MMP3_HUMAN	Decreases Expression	[118]
Dihydropteridine reductase (QDPR)	OTSKOIUX	DHPR_HUMAN	Decreases Activity	[123]
Poly polymerase 1 (PARP1)	OT310QSG	PARP1_HUMAN	Increases Cleavage	[124]
Intestinal-type alkaline phosphatase (ALPI)	OTTQ468O	PPBI_HUMAN	Increases Activity	[125]
Adenosine receptor A3 (ADORA3)	OTHO1BLK	AA3R_HUMAN	Increases Expression	[126]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Decreases Expression	[118]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Decreases Expression	[127]
Ornithine decarboxylase (ODC1)	OTNDAGRR	DCOR_HUMAN	Increases Expression	[125]
Bone morphogenetic protein 2 (BMP2)	OT23T37S	BMP2_HUMAN	Increases Expression	[114]
Tissue factor (F3)	OT3MSU3B	TF_HUMAN	Increases Expression	[128]
Matrix metalloproteinase-9 (MMP9)	OTB2QDAV	MMP9_HUMAN	Increases Expression	[110]
Aminopeptidase N (ANPEP)	OTP3WYFD	AMPN_HUMAN	Increases Expression	[129]
Histone H2AX (H2AX)	OT18UX57	H2AX_HUMAN	Increases Phosphorylation	[130]
Cyclic AMP-responsive element-binding protein 1 (CREB1)	OT1MDLA1	CREB1_HUMAN	Decreases Expression	[112]
E-selectin (SELE)	OT33RZWY	LYAM2_HUMAN	Decreases Expression	[118]
Platelet glycoprotein 4 (CD36)	OT5CZWKY	CD36_HUMAN	Increases Expression	[131]
Interleukin-7 receptor subunit alpha (IL7R)	OTBMFLQQ	IL7RA_HUMAN	Decreases Expression	[112]
Desmin (DES)	OTI09KBW	DESM_HUMAN	Increases Expression	[132]
Insulin-like growth factor-binding protein 3 (IGFBP3)	OTIX63TX	IBP3_HUMAN	Increases Expression	[69]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3)	OTC1UOHP	ATF3_HUMAN	Increases Expression	[71]
Nuclear factor NF-kappa-B p105 subunit (NFKB1)	OTNRRD8I	NFKB1_HUMAN	Decreases Expression	[115]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)	OTVLI4DD	TNAP3_HUMAN	Decreases Expression	[110]
Interleukin-10 (IL10)	OTIRFRXC	IL10_HUMAN	Increases Expression	[113]
Integrin alpha-6 (ITGA6)	OT3FA39C	ITA6_HUMAN	Increases Expression	[69]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)	OTDRV63V	GA45A_HUMAN	Increases Expression	[133]
Cyclin-dependent kinase 2 (CDK2)	OTB5DYYZ	CDK2_HUMAN	Increases Expression	[110]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Decreases Expression	[127]
Dual specificity protein phosphatase 1 (DUSP1)	OTN6BR75	DUS1_HUMAN	Increases Expression	[113]
Adenosine receptor A2a (ADORA2A)	OTVRBZ0I	AA2AR_HUMAN	Increases Expression	[134]
Adenosine receptor A2b (ADORA2B)	OTCDYBBP	AA2BR_HUMAN	Increases Expression	[134]
Interleukin-12 subunit alpha (IL12A)	OTDQT8GI	IL12A_HUMAN	Decreases Expression	[135]
14-3-3 protein sigma (SFN)	OTLJCZ1U	1433S_HUMAN	Increases Expression	[69]
Macrosialin (CD68)	OTOYEY3J	CD68_HUMAN	Decreases Expression	[136]
Interleukin-13 (IL13)	OTI4YS3Y	IL13_HUMAN	Decreases Secretion	[119]
Basigin (BSG)	OTD0CVEC	BASI_HUMAN	Decreases Expression	[112]
TGF-beta receptor type-2 (TGFBR2)	OT3P7GZP	TGFR2_HUMAN	Decreases Expression	[112]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[130]
Caspase-3 (CASP3)	OTIJRBE7	CASP3_HUMAN	Increases Expression	[137]
Nuclear receptor subfamily 4 group A member 2 (NR4A2)	OT3F9IR2	NR4A2_HUMAN	Decreases Expression	[136]
Mitogen-activated protein kinase 9 (MAPK9)	OTCEVJ9E	MK09_HUMAN	Increases Expression	[138]
Cyclin-dependent kinase inhibitor 1B (CDKN1B)	OTNY5LLZ	CDN1B_HUMAN	Increases Expression	[138]
MAP kinase-activated protein kinase 2 (MAPKAPK2)	OT460SBO	MAPK2_HUMAN	Increases Expression	[113]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10)	OT4PXBTA	TNF10_HUMAN	Increases Expression	[110]
Caveolin-2 (CAV2)	OT1FGRQX	CAV2_HUMAN	Increases Expression	[69]
Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6)	OTK13JKC	MP2K6_HUMAN	Decreases Expression	[113]
Collagen alpha-4(IV) chain (COL4A4)	OT9G0MCT	CO4A4_HUMAN	Increases Expression	[132]
Phospholipid transfer protein (PLTP)	OTVJJO5Z	PLTP_HUMAN	Increases Expression	[69]
Caspase-6 (CASP6)	OTXLD3EC	CASP6_HUMAN	Decreases Expression	[133]
Cadherin-4 (CDH4)	OT8LH3HN	CADH4_HUMAN	Decreases Expression	[69]
Interleukin-2 (IL2)	OTGI4NSA	IL2_HUMAN	Decreases Secretion	[139]
Actin-related protein 2 (ACTR2)	OT3C8U5T	ARP2_HUMAN	Decreases Expression	[112]
Actin, aortic smooth muscle (ACTA2)	OTEDLG8E	ACTA_HUMAN	Increases Expression	[119]
Ras-related C3 botulinum toxin substrate 1 (RAC1)	OTKRO61U	RAC1_HUMAN	Increases Expression	[113]
Protein jagged-1 (JAG1)	OT3LGT6K	JAG1_HUMAN	Increases Expression	[69]
Protein S100-A12 (S100A12)	OTF9IIXW	S10AC_HUMAN	Increases Expression	[110]
CD83 antigen (CD83)	OT1V4WQF	CD83_HUMAN	Decreases Expression	[110]
Transgelin (TAGLN)	OTAEZ0KP	TAGL_HUMAN	Decreases Expression	[67]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)	OT2YYI1A	MCL1_HUMAN	Increases Expression	[110]
Bcl-2-interacting killer (BIK)	OTTH1T3D	BIK_HUMAN	Increases Expression	[133]
RING-type E3 ubiquitin-protein ligase PPIL2 (PPIL2)	OTL9Y4IO	PPIL2_HUMAN	Decreases Expression	[112]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)	OTXEE550	APR_HUMAN	Increases Expression	[130]
Frizzled-2 (FZD2)	OT952ML1	FZD2_HUMAN	Decreases Expression	[69]
Structural maintenance of chromosomes protein 1A (SMC1A)	OT9ZMRK9	SMC1A_HUMAN	Decreases Expression	[112]
Angiopoietin-1 (ANGPT1)	OTVZ1NG3	ANGP1_HUMAN	Decreases Expression	[66]
Histone-lysine N-methyltransferase EZH2 (EZH2)	OTIEHTKW	EZH2_HUMAN	Decreases Expression	[130]
Mitogen-activated protein kinase 14 (MAPK14)	OT5TCO3O	MK14_HUMAN	Decreases Expression	[113]
Occludin (OCLN)	OTSUTVWL	OCLN_HUMAN	Decreases Expression	[115]
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 (B3GNT9)	OTO385AU	B3GN9_HUMAN	Increases Expression	[69]
Jouberin (AHI1)	OT8K2YWY	AHI1_HUMAN	Increases Expression	[140]
Retinoic acid-induced protein 3 (GPRC5A)	OTPOCWR7	RAI3_HUMAN	Increases Expression	[69]
Aquaporin-3 (AQP3)	OT2J7JPD	AQP3_HUMAN	Decreases Expression	[110]
Protein Jumonji (JARID2)	OT14UM8H	JARD2_HUMAN	Decreases Expression	[71]
Bcl-2-binding component 3, isoforms 3/4 (BBC3)	OTUAXDAY	BBC3B_HUMAN	Increases Expression	[130]
Perilipin-2 (PLIN2)	OTRXJ9UN	PLIN2_HUMAN	Increases Expression	[69]
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5)	OTH91ETM	SIA7E_HUMAN	Decreases Expression	[69]
Protein FAM117A (FAM117A)	OT2FBGGV	F117A_HUMAN	Decreases Expression	[71]
Proline-serine-threonine phosphatase-interacting protein 2 (PSTPIP2)	OTG6F93V	PPIP2_HUMAN	Increases Expression	[69]
Bcl-2-like protein 12 (BCL2L12)	OTS6IFZY	B2L12_HUMAN	Decreases Expression	[141]
Mid1-interacting protein 1 (MID1IP1)	OTFCORJM	M1IP1_HUMAN	Increases Expression	[69]
AP-5 complex subunit sigma-1 (AP5S1)	OTGS53SC	AP5S1_HUMAN	Increases Expression	[71]
DNA damage-inducible transcript 4 protein (DDIT4)	OTHY8SY4	DDIT4_HUMAN	Increases Expression	[69]
Heat shock protein beta-8 (HSPB8)	OT0I83YS	HSPB8_HUMAN	Increases Expression	[69]
Endothelial protein C receptor (PROCR)	OTRHED17	EPCR_HUMAN	Increases Expression	[69]
Forkhead box protein J3 (FOXJ3)	OTXAUJ47	FOXJ3_HUMAN	Decreases Expression	[112]
RWD domain-containing protein 3 (RWDD3)	OTE76DY5	RWDD3_HUMAN	Increases Expression	[71]
Dual specificity protein phosphatase 10 (DUSP10)	OTNG467B	DUS10_HUMAN	Increases Expression	[113]
Elongation factor 1-alpha 1 (EEF1A1)	OT00THXS	EF1A1_HUMAN	Decreases Response To Substance	[142]
Glycoprotein hormones alpha chain (CGA)	OT00U3Y3	GLHA_HUMAN	Affects Response To Substance	[72]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5)	OT03QCLM	ATF5_HUMAN	Affects Response To Substance	[72]
Mediator of RNA polymerase II transcription subunit 15 (MED15)	OT0D0JVD	MED15_HUMAN	Affects Response To Substance	[72]
Phospholipid phosphatase 1 (PLPP1)	OT0IIMI5	PLPP1_HUMAN	Affects Response To Substance	[72]
Guanine nucleotide-binding protein subunit alpha-11 (GNA11)	OT0K99TO	GNA11_HUMAN	Affects Response To Substance	[72]
Succinate--CoA ligase subunit beta, mitochondrial (SUCLG2)	OT0KHLY2	SUCB2_HUMAN	Affects Response To Substance	[72]
Insulin-like growth factor-binding protein 7 (IGFBP7)	OT1D416P	IBP7_HUMAN	Affects Response To Substance	[72]
Alpha-centractin (ACTR1A)	OT1QAU16	ACTZ_HUMAN	Affects Response To Substance	[72]
Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1)	OT1QHOS2	NF2L1_HUMAN	Affects Response To Substance	[72]
DNA-directed RNA polymerase I subunit RPA12 (POLR1H)	OT30S3SB	RPA12_HUMAN	Decreases Response To Substance	[143]
Epidermal growth factor-like protein 6 (EGFL6)	OT331X59	EGFL6_HUMAN	Decreases Response To Substance	[73]
Protein FAM171A1 (FAM171A1)	OT33BHEP	F1711_HUMAN	Affects Response To Substance	[72]
Cip1-interacting zinc finger protein (CIZ1)	OT3UKHPI	CIZ1_HUMAN	Affects Response To Substance	[72]
Transcobalamin-2 (TCN2)	OT41D0L3	TCO2_HUMAN	Affects Metabolism	[144]
Elafin (PI3)	OT47MTC3	ELAF_HUMAN	Affects Response To Substance	[72]
CCR4-NOT transcription complex subunit 3 (CNOT3)	OT4D5Z9L	CNOT3_HUMAN	Affects Response To Substance	[72]
ATP-dependent RNA helicase DHX15 (DHX15)	OT4F98TK	DHX15_HUMAN	Affects Response To Substance	[72]
Fibroblast growth factor receptor 1 (FGFR1)	OT4GLCXW	FGFR1_HUMAN	Affects Response To Substance	[72]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)	OT4SO7J4	BNIP3_HUMAN	Affects Response To Substance	[72]
PRELI domain containing protein 3B (PRELID3B)	OT4TRT4K	PLD3B_HUMAN	Affects Response To Substance	[72]
Exocyst complex component 7 (EXOC7)	OT4YA137	EXOC7_HUMAN	Affects Response To Substance	[72]
Large proline-rich protein BAG6 (BAG6)	OT4Z0S2U	BAG6_HUMAN	Affects Response To Substance	[72]
Transducin-like enhancer protein 1 (TLE1)	OT50MRZ1	TLE1_HUMAN	Affects Response To Substance	[72]
Protein phosphatase 3 catalytic subunit alpha (PPP3CA)	OT58PUEN	PP2BA_HUMAN	Affects Response To Substance	[72]
Transcription termination factor 2 (TTF2)	OT5LJOWM	TTF2_HUMAN	Affects Response To Substance	[72]
Protein kinase C alpha type (PRKCA)	OT5UWNRD	KPCA_HUMAN	Decreases Response To Substance	[98]
Collagen alpha-2(V) chain (COL5A2)	OT5VOSQE	CO5A2_HUMAN	Decreases Response To Substance	[73]
Nuclear pore complex protein Nup88 (NUP88)	OT647WOR	NUP88_HUMAN	Affects Response To Substance	[72]
Mitochondrial enolase superfamily member 1 (ENOSF1)	OT65D3ZK	ENOF1_HUMAN	Affects Response To Substance	[72]
C-C motif chemokine 4 (CCL4)	OT6B8P25	CCL4_HUMAN	Decreases Response To Substance	[145]
Melanoma-associated antigen D1 (MAGED1)	OT6EOLFC	MAGD1_HUMAN	Affects Response To Substance	[72]
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PPRC1)	OT6GB3WR	PPRC1_HUMAN	Affects Response To Substance	[72]
Follistatin-related protein 1 (FSTL1)	OT6KEZUD	FSTL1_HUMAN	Affects Response To Substance	[72]
Glutathione peroxidase 3 (GPX3)	OT6PK94R	GPX3_HUMAN	Affects Response To Substance	[72]
Dual specificity protein phosphatase 4 (DUSP4)	OT6WAO12	DUS4_HUMAN	Affects Response To Substance	[72]
Semenogelin-1 (SEMG1)	OT6Z4BPQ	SEMG1_HUMAN	Affects Response To Substance	[72]
GTPase KRas (KRAS)	OT78QCN8	RASK_HUMAN	Increases Response To Substance	[146]
Polyunsaturated fatty acid 5-lipoxygenase (ALOX5)	OT7FOIK2	LOX5_HUMAN	Affects Response To Substance	[72]
Glutamate receptor ionotropic, NMDA 3B (GRIN3B)	OT7T1OJP	NMD3B_HUMAN	Affects Response To Substance	[72]
Interferon-inducible protein AIM2 (AIM2)	OT86QUI8	AIM2_HUMAN	Affects Response To Substance	[72]
Tyrosine-protein kinase Lck (LCK)	OT883FG9	LCK_HUMAN	Affects Response To Substance	[72]
Peroxisomal membrane protein 11A (PEX11A)	OT8MJ9CJ	PX11A_HUMAN	Affects Response To Substance	[72]
Mediator of RNA polymerase II transcription subunit 16 (MED16)	OT8SCI48	MED16_HUMAN	Affects Response To Substance	[72]
Annexin A11 (ANXA11)	OT8SRY1C	ANX11_HUMAN	Affects Response To Substance	[72]
ER lumen protein-retaining receptor 1 (KDELR1)	OT8YBS5G	ERD21_HUMAN	Affects Response To Substance	[72]
Prostate tumor-overexpressed gene 1 protein (PTOV1)	OT94WT5X	PTOV1_HUMAN	Affects Response To Substance	[72]
Cyclic AMP-responsive element-binding protein 3 (CREB3)	OT9617UO	CREB3_HUMAN	Affects Response To Substance	[72]
Runt-related transcription factor 2 (RUNX2)	OT97RQQM	RUNX2_HUMAN	Decreases Response To Substance	[114]
Fibromodulin (FMOD)	OT9EJ5H8	FMOD_HUMAN	Affects Response To Substance	[72]
Epsilon-sarcoglycan (SGCE)	OT9F17JB	SGCE_HUMAN	Affects Response To Substance	[72]
Tyrosine-protein kinase Fer (FER)	OT9JR7AE	FER_HUMAN	Affects Response To Substance	[72]
Receptor-type tyrosine-protein phosphatase gamma (PTPRG)	OT9N2WOF	PTPRG_HUMAN	Affects Response To Substance	[72]
Extended synaptotagmin-1 (ESYT1)	OTA8NSJF	ESYT1_HUMAN	Affects Response To Substance	[72]
HLA class I histocompatibility antigen, A alpha chain (HLA-A)	OTAH14LU	HLAA_HUMAN	Affects Response To Substance	[72]
Cleavage and polyadenylation specificity factor subunit 1 (CPSF1)	OTAU1KOM	CPSF1_HUMAN	Affects Response To Substance	[72]
PDZ and LIM domain protein 7 (PDLIM7)	OTAZVODU	PDLI7_HUMAN	Affects Response To Substance	[72]
Coagulation factor XII (F12)	OTBFD2FU	FA12_HUMAN	Affects Response To Substance	[72]
Protein DGCR6 (DGCR6)	OTBOXM33	DGCR6_HUMAN	Affects Response To Substance	[72]
Histone H1.10 (H1-10)	OTBWDA4E	H1X_HUMAN	Affects Response To Substance	[72]
Potassium channel subfamily K member 1 (KCNK1)	OTBXPTKX	KCNK1_HUMAN	Affects Response To Substance	[72]
CCN family member 2 (CCN2)	OTC39NSU	CCN2_HUMAN	Decreases Response To Substance	[147]
Serine protease HTRA2, mitochondrial (HTRA2)	OTC7616F	HTRA2_HUMAN	Affects Response To Substance	[145]
Cystathionine gamma-lyase (CTH)	OTC90LA0	CGL_HUMAN	Affects Response To Substance	[72]
Creatine kinase U-type, mitochondrial (CKMT1A)	OTCINHH5	KCRU_HUMAN	Affects Response To Substance	[72]
KRR1 small subunit processome component homolog (KRR1)	OTCMJ3K3	KRR1_HUMAN	Affects Response To Substance	[72]
Phosphoribosylformylglycinamidine synthase (PFAS)	OTCOBYYK	PUR4_HUMAN	Affects Response To Substance	[103]
Adhesion G protein-coupled receptor L2 (ADGRL2)	OTCXD2YR	AGRL2_HUMAN	Affects Response To Substance	[72]
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS)	OTCYYCAC	HGS_HUMAN	Affects Response To Substance	[72]
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1)	OTD13PJN	RBMS1_HUMAN	Affects Response To Substance	[72]
Src kinase-associated phosphoprotein 1 (SKAP1)	OTD4ZKAL	SKAP1_HUMAN	Affects Response To Substance	[72]
Battenin (CLN3)	OTDDKT8R	CLN3_HUMAN	Affects Response To Substance	[72]
Integrin alpha-1 (ITGA1)	OTDITIST	ITA1_HUMAN	Increases Response To Substance	[73]
Multiple epidermal growth factor-like domains protein 9 (MEGF9)	OTDQWTY4	MEGF9_HUMAN	Affects Response To Substance	[72]
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1)	OTDS5WAU	PIN1_HUMAN	Affects Response To Substance	[72]
Cytoskeleton-associated protein 4 (CKAP4)	OTDUC9ME	CKAP4_HUMAN	Affects Response To Substance	[72]
Transcription intermediary factor 1-beta (TRIM28)	OTE38OBF	TIF1B_HUMAN	Affects Response To Substance	[72]
Cystatin-SN (CST1)	OTE4I83Q	CYTN_HUMAN	Affects Response To Substance	[72]
Pseudouridine-5'-phosphatase (PUDP)	OTEPEJLX	HDHD1_HUMAN	Affects Response To Substance	[72]
Rho GDP-dissociation inhibitor 1 (ARHGDIA)	OTEXWJDO	GDIR1_HUMAN	Affects Response To Substance	[72]
Caveolin-1 (CAV1)	OTEZUR1L	CAV1_HUMAN	Decreases Response To Substance	[98]
Methionine synthase (MTR)	OTF2K2TA	METH_HUMAN	Decreases Response To Substance	[103]
CD151 antigen (CD151)	OTF3UZS7	CD151_HUMAN	Affects Response To Substance	[72]
Paraneoplastic antigen Ma2 (PNMA2)	OTF5YBQG	PNMA2_HUMAN	Affects Response To Substance	[72]
Endophilin-B2 (SH3GLB2)	OTF7BB9S	SHLB2_HUMAN	Affects Response To Substance	[72]
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C)	OTF7CGO2	2A5G_HUMAN	Affects Response To Substance	[72]
Dehydrogenase/reductase SDR family member 2, mitochondrial (DHRS2)	OTFHWIY8	DHRS2_HUMAN	Affects Response To Substance	[72]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Increases Response To Substance	[98]
Laminin subunit alpha-2 (LAMA2)	OTFROQWE	LAMA2_HUMAN	Increases Response To Substance	[73]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1)	OTFRWOLM	HNRH1_HUMAN	Affects Response To Substance	[72]
m7GpppN-mRNA hydrolase (DCP2)	OTG3VKPS	DCP2_HUMAN	Affects Response To Substance	[72]
Leucine-rich repeat transmembrane protein FLRT2 (FLRT2)	OTGD8TID	FLRT2_HUMAN	Affects Response To Substance	[72]
Tomoregulin-1 (TMEFF1)	OTH6M3CH	TEFF1_HUMAN	Affects Response To Substance	[72]
Phospholipid-transporting ATPase ABCA3 (ABCA3)	OTH6MSKQ	ABCA3_HUMAN	Decreases Response To Substance	[148]
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (GNG11)	OTHIXBGW	GBG11_HUMAN	Affects Response To Substance	[72]
Melanoma-associated antigen 6 (MAGEA6)	OTI8S0O2	MAGA6_HUMAN	Affects Response To Substance	[72]
Nectin-2 (NECTIN2)	OTIE0W6O	NECT2_HUMAN	Affects Response To Substance	[72]
Kallikrein-6 (KLK6)	OTIEA234	KLK6_HUMAN	Affects Response To Substance	[72]
Laminin subunit gamma-1 (LAMC1)	OTIG527N	LAMC1_HUMAN	Affects Response To Substance	[72]
Serine hydroxymethyltransferase, cytosolic (SHMT1)	OTIINA3J	GLYC_HUMAN	Affects Response To Substance	[149]
Spartin (SPART)	OTIVOS2I	SPART_HUMAN	Affects Response To Substance	[72]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Affects Response To Substance	[72]
Polycomb protein EED (EED)	OTJFHCDF	EED_HUMAN	Affects Response To Substance	[72]
Sulfate transporter (SLC26A2)	OTJNHNTO	S26A2_HUMAN	Affects Response To Substance	[72]
Lysophosphatidic acid receptor 1 (LPAR1)	OTJNJQPF	LPAR1_HUMAN	Affects Response To Substance	[72]
Unconventional myosin-VI (MYO6)	OTJQYRC7	MYO6_HUMAN	Affects Response To Substance	[72]
Tetraspanin-4 (TSPAN4)	OTKFK57F	TSN4_HUMAN	Affects Response To Substance	[72]
Interferon regulatory factor 6 (IRF6)	OTKJ44EV	IRF6_HUMAN	Affects Response To Substance	[72]
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3BGRL3)	OTKMW34I	SH3L3_HUMAN	Affects Response To Substance	[72]
Ras-related protein Rab-1A (RAB1A)	OTKPHRD0	RAB1A_HUMAN	Affects Response To Substance	[72]
5'-3' exonuclease PLD3 (PLD3)	OTL07SP2	PLD3_HUMAN	Affects Response To Substance	[72]
Protein S100-A4 (S100A4)	OTLRGFSQ	S10A4_HUMAN	Decreases Response To Substance	[150]
Death-associated protein kinase 3 (DAPK3)	OTLV7EKW	DAPK3_HUMAN	Affects Response To Substance	[72]
Peroxiredoxin-2 (PRDX2)	OTLWCY9T	PRDX2_HUMAN	Decreases Response To Substance	[151]
Hemicentin-1 (HMCN1)	OTLZAS0P	HMCN1_HUMAN	Increases Response To Substance	[73]
Unconventional myosin-Ie (MYO1E)	OTM9YSIZ	MYO1E_HUMAN	Affects Response To Substance	[72]
kinase isozyme 1, mitochondrial (PDK1)	OTMABK9Z	PDK1_HUMAN	Affects Response To Substance	[72]
NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8)	OTMEAWKO	NDUS8_HUMAN	Affects Response To Substance	[72]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)	OTMKHVWC	C1TC_HUMAN	Affects Response To Substance	[152]
Ubiquitin-conjugating enzyme E2 R1 (CDC34)	OTNBK390	UB2R1_HUMAN	Affects Response To Substance	[72]
Glycine cleavage system H protein, mitochondrial (GCSH)	OTNC1OKA	GCSH_HUMAN	Affects Response To Substance	[72]
Pulmonary surfactant-associated protein D (SFTPD)	OTNKPDJC	SFTPD_HUMAN	Increases ADR	[74]
Hepatoma-derived growth factor-related protein 3 (HDGFL3)	OTNN7WYH	HDGR3_HUMAN	Affects Response To Substance	[72]
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE)	OTNONPMB	GLCNE_HUMAN	Affects Response To Substance	[72]
Splicing factor 3B subunit 1 (SF3B1)	OTNTX2DG	SF3B1_HUMAN	Affects Response To Substance	[72]
Protein Tob1 (TOB1)	OTNW949D	TOB1_HUMAN	Affects Response To Substance	[72]
ADP-ribosylation factor-like protein 6-interacting protein 4 (ARL6IP4)	OTOA8VAL	AR6P4_HUMAN	Affects Response To Substance	[72]
Forkhead box protein N3 (FOXN3)	OTOJYJZP	FOXN3_HUMAN	Affects Response To Substance	[72]
Glutathione S-transferase Mu 4 (GSTM4)	OTOTF8DU	GSTM4_HUMAN	Decreases Response To Substance	[153]
Solute carrier family 52, riboflavin transporter, member 2 (SLC52A2)	OTPC6NXA	S52A2_HUMAN	Affects Response To Substance	[72]
Poly(A) polymerase alpha (PAPOLA)	OTPHD65D	PAPOA_HUMAN	Affects Response To Substance	[72]
Centrosomal protein of 57 kDa (CEP57)	OTPOHLIX	CEP57_HUMAN	Affects Response To Substance	[72]
CD99 antigen (CD99)	OTPUZ5DE	CD99_HUMAN	Affects Response To Substance	[72]
Large ribosomal subunit protein uL23 (RPL23A)	OTPYLCCX	RL23A_HUMAN	Affects Response To Substance	[72]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)	OTPYQX3K	C1QBP_HUMAN	Decreases Response To Substance	[154]
Bone morphogenetic protein 4 (BMP4)	OTPZMDFH	BMP4_HUMAN	Decreases Response To Substance	[114]
Inosine triphosphate pyrophosphatase (ITPA)	OTQ47WVR	ITPA_HUMAN	Affects Response To Substance	[155]
45 kDa calcium-binding protein (SDF4)	OTQ7WFYW	CAB45_HUMAN	Affects Response To Substance	[72]
Eukaryotic translation initiation factor 5A-1 (EIF5A)	OTQ8DJX5	IF5A1_HUMAN	Affects Response To Substance	[72]
Lactadherin (MFGE8)	OTQKE41R	MFGM_HUMAN	Affects Response To Substance	[72]
Calsyntenin-1 (CLSTN1)	OTQN35G2	CSTN1_HUMAN	Affects Response To Substance	[72]
Histone deacetylase 4 (HDAC4)	OTQNGD32	HDAC4_HUMAN	Affects Response To Substance	[72]
Double-stranded RNA-specific adenosine deaminase (ADAR)	OTQNOHR8	DSRAD_HUMAN	Decreases Response To Substance	[156]
Keratin, type I cytoskeletal 23 (KRT23)	OTQW6UAG	K1C23_HUMAN	Increases Response To Substance	[73]
Transforming growth factor-beta-induced protein ig-h3 (TGFBI)	OTR443C5	BGH3_HUMAN	Decreases Response To Substance	[73]
Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2)	OTR99SJ8	CDKA2_HUMAN	Affects Response To Substance	[72]
TNFAIP3-interacting protein 1 (TNIP1)	OTRAOTEW	TNIP1_HUMAN	Affects Response To Substance	[145]
Diamine oxidase (AOC1)	OTRC220K	AOC1_HUMAN	Affects Response To Substance	[72]
Dickkopf-related protein 1 (DKK1)	OTRDLUSP	DKK1_HUMAN	Decreases Response To Substance	[142]
Methyl-CpG-binding domain protein 3 (MBD3)	OTRL76H5	MBD3_HUMAN	Affects Response To Substance	[72]
Gamma-enolase (ENO2)	OTRODL0T	ENOG_HUMAN	Decreases Response To Substance	[98]
Dr1-associated corepressor (DRAP1)	OTRWLF6D	NC2A_HUMAN	Affects Response To Substance	[72]
Glutathione S-transferase Mu 1 (GSTM1)	OTSBF2MO	GSTM1_HUMAN	Decreases Response To Substance	[153]
Protein kinase C delta type (PRKCD)	OTSEH90E	KPCD_HUMAN	Affects Response To Substance	[145]
Formin-binding protein 1 (FNBP1)	OTSJ5KKA	FNBP1_HUMAN	Affects Response To Substance	[72]
Lumican (LUM)	OTSRC874	LUM_HUMAN	Decreases Response To Substance	[73]
Collagen alpha-1(III) chain (COL3A1)	OTT1EMLM	CO3A1_HUMAN	Decreases Response To Substance	[73]
Mesothelin (MSLN)	OTT23UM3	MSLN_HUMAN	Affects Response To Substance	[72]
NKG2-C type II integral membrane protein (KLRC2)	OTT4N86S	NKG2C_HUMAN	Affects Response To Substance	[72]
Talin-1 (TLN1)	OTTD2YXM	TLN1_HUMAN	Affects Response To Substance	[72]
Collagen alpha-1(XV) chain (COL15A1)	OTTFKK18	COFA1_HUMAN	Decreases Response To Substance	[73]
Adipogenesis regulatory factor (ADIRF)	OTTJP8D4	ADIRF_HUMAN	Affects Response To Substance	[72]
CASP8-associated protein 2 (CASP8AP2)	OTTWT68S	C8AP2_HUMAN	Increases Response To Substance	[145]
Rab11 family-interacting protein 2 (RAB11FIP2)	OTTX9RWE	RFIP2_HUMAN	Affects Response To Substance	[72]
Protein disulfide-isomerase (P4HB)	OTTYNYPF	PDIA1_HUMAN	Affects Response To Substance	[72]
AMP deaminase 1 (AMPD1)	OTU17BCI	AMPD1_HUMAN	Affects Response To Substance	[155]
Period circadian protein homolog 2 (PER2)	OTU2B1DJ	PER2_HUMAN	Affects Response To Substance	[72]
Methylenetetrahydrofolate reductase (MTHFR)	OTUBJSR7	MTHR_HUMAN	Increases ADR	[157]
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2)	OTUE7Z91	MP2K2_HUMAN	Affects Response To Substance	[72]
Prosaposin (PSAP)	OTUOEKY7	SAP_HUMAN	Affects Response To Substance	[72]
AT-rich interactive domain-containing protein 5B (ARID5B)	OTUQ4CQY	ARI5B_HUMAN	Affects Abundance	[158]
Acyl-CoA 6-desaturase (FADS2)	OTUX531P	FADS2_HUMAN	Affects Response To Substance	[72]
Guanidinoacetate N-methyltransferase (GAMT)	OTVC87ES	GAMT_HUMAN	Affects Response To Substance	[72]
Matrilin-2 (MATN2)	OTVDR68G	MATN2_HUMAN	Decreases Response To Substance	[73]
Membralin (TMEM259)	OTVH9HD8	MBRL_HUMAN	Affects Response To Substance	[72]
ATP-binding cassette sub-family C member 11 (ABCC11)	OTVHL7OR	MRP8_HUMAN	Decreases Abundance	[91]
Nicotinamide phosphoribosyltransferase (NAMPT)	OTVJR3GL	NAMPT_HUMAN	Affects Response To Substance	[159]
GTPase NRas (NRAS)	OTVQ1DG3	RASN_HUMAN	Increases Response To Substance	[146]
Ensconsin (MAP7)	OTVSSJ33	MAP7_HUMAN	Affects Response To Substance	[72]
ATP-binding cassette sub-family A member 2 (ABCA2)	OTVSYK0X	ABCA2_HUMAN	Decreases Response To Substance	[148]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3)	OTVT1Q25	B3GN3_HUMAN	Affects Response To Substance	[72]
E3 ubiquitin-protein ligase KCMF1 (KCMF1)	OTVTKFAU	KCMF1_HUMAN	Affects Response To Substance	[72]
PHD finger protein 10 (PHF10)	OTWDR4EX	PHF10_HUMAN	Affects Response To Substance	[72]
Decorin (DCN)	OTWLJL7K	PGS2_HUMAN	Decreases Response To Substance	[73]
Phosphatase and actin regulator 2 (PHACTR2)	OTWMX2A8	PHAR2_HUMAN	Affects Response To Substance	[72]
Periostin (POSTN)	OTWP62UA	POSTN_HUMAN	Decreases Response To Substance	[73]
Bcl-2-related protein A1 (BCL2A1)	OTWRYSNA	B2LA1_HUMAN	Decreases Response To Substance	[145]
Glypican-3 (GPC3)	OTWS8WSW	GPC3_HUMAN	Increases Response To Substance	[73]
CD302 antigen (CD302)	OTX580VU	CD302_HUMAN	Affects Response To Substance	[72]
Arfaptin-1 (ARFIP1)	OTXHWO6M	ARFP1_HUMAN	Affects Response To Substance	[72]
Glutathione peroxidase 2 (GPX2)	OTXI2NTI	GPX2_HUMAN	Affects Response To Substance	[72]
Bifunctional glutamate/proline--tRNA ligase (EPRS1)	OTXK0FLB	SYEP_HUMAN	Affects Response To Substance	[72]
ATP synthase subunit delta, mitochondrial (ATP5F1D)	OTXTAG2V	ATPD_HUMAN	Affects Response To Substance	[72]
Carbamoyl-phosphate synthase , mitochondrial (CPS1)	OTXV8NSR	CPSM_HUMAN	Affects Response To Substance	[72]
Progranulin (GRN)	OTXXSJ53	GRN_HUMAN	Affects Response To Substance	[72]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PIK3C2B)	OTY2PROB	P3C2B_HUMAN	Affects Response To Substance	[72]
Thymidine kinase, cytosolic (TK1)	OTY5JFM1	KITH_HUMAN	Increases ADR	[74]
Collagen alpha-2(I) chain (COL1A2)	OTY7G382	CO1A2_HUMAN	Increases Response To Substance	[73]
Calreticulin (CALR)	OTYD2TR1	CALR_HUMAN	Affects Response To Substance	[72]
Lysosome-associated membrane glycoprotein 1 (LAMP1)	OTYE92QY	LAMP1_HUMAN	Increases ADR	[74]
BTB/POZ domain-containing protein 3 (BTBD3)	OTZ607YT	BTBD3_HUMAN	Affects Response To Substance	[72]
Ena/VASP-like protein (EVL)	OTZ8ZDNY	EVL_HUMAN	Affects Response To Substance	[72]
Protein BTG2 (BTG2)	OTZF6K1H	BTG2_HUMAN	Affects Response To Substance	[145]
Aspartate aminotransferase, cytoplasmic (GOT1)	OTZLM5UB	AATC_HUMAN	Increases ADR	[74]
Lysine-specific demethylase 6A (KDM6A)	OTZM3MJJ	KDM6A_HUMAN	Affects Response To Substance	[72]
Alkaline phosphatase, placental type (ALPP)	OTZU4G9W	PPB1_HUMAN	Affects Response To Substance	[72]
Drebrin (DBN1)	OTZVKG8A	DREB_HUMAN	Affects Response To Substance	[72]

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Melanoma	DCLURX1	MALME-3M	Investigative	[160]

References

• [1] Biologically active neutrophil chemokine pattern in tonsillitis.Clin Exp Immunol. 2004 Mar;135(3):511-8. doi: 10.1111/j.1365-2249.2003.02390.x.
• [2] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1015).
• [3] Methotrexate FDA Label
• [4] FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 040632.
• [5] Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for ... Trials. 2015 Mar 4;16:77.
• [6] ClinicalTrials.gov (NCT04136366) The GUARD Trial - Part 1: A Phase 3 Clinical Trial for Prevention of Proliferative Vitreoretinopathy. U.S. National Institutes of Health.
• [7] ClinicalTrials.gov (NCT04352465) Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients. U.S. National Institutes of Health.
• [8] Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034238)
• [9] The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
• [10] Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation. J Mol Endocrinol. 2004 Apr;32(2):397-414.
• [11] Gene expression profiles with activation of the estrogen receptor alpha-selective estrogen receptor modulator complex in breast cancer cells expressing wild-type estrogen receptor. Cancer Res. 2002 Aug 1;62(15):4419-26.
• [12] Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells. J Cell Biochem. 2006 Aug 1;98(5):1163-84.
• [13] Moving toward integrating gene expression profiling into high-throughput testing: a gene expression biomarker accurately predicts estrogen receptor alpha modulation in a microarray compendium. Toxicol Sci. 2016 May;151(1):88-103.
• [14] DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer. Clin Epigenetics. 2019 Oct 10;11(1):138. doi: 10.1186/s13148-019-0725-y.
• [15] mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels. Cancer Sci. 2008 Oct;99(10):1992-2003. doi: 10.1111/j.1349-7006.2008.00955.x.
• [16] Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
• [17] The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells. Oncol Rep. 2010 Apr;23(4):1109-17. doi: 10.3892/or_00000739.
• [18] Beta3-tubulin is induced by estradiol in human breast carcinoma cells through an estrogen-receptor dependent pathway. Cell Motil Cytoskeleton. 2009 Jul;66(7):378-88.
• [19] Fulvestrant: pharmacologic profile versus existing endocrine agents for the treatment of breast cancer. Ann Pharmacother. 2006 Sep;40(9):1572-83.
• [20] Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue. Mol Pharmacol. 2006 Mar;69(3):908-20.
• [21] Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin. J Soc Gynecol Investig. 2005 Oct;12(7):e55-67.
• [22] Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. Mol Endocrinol. 2010 Jan;24(1):33-46.
• [23] Red clover aryl hydrocarbon receptor (AhR) and estrogen receptor (ER) agonists enhance genotoxic estrogen metabolism. Chem Res Toxicol. 2017 Nov 20;30(11):2084-2092.
• [24] Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ transcript in estrogen receptor-positive MCF-7 breast cancer cells. Clin Biochem. 2009 Sep;42(13-14):1358-62. doi: 10.1016/j.clinbiochem.2009.05.017. Epub 2009 Jun 6.
• [25] Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER. BMC Cancer. 2015 Oct 15;15:702. doi: 10.1186/s12885-015-1699-6.
• [26] Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR). Toxicol Appl Pharmacol. 2005 Dec 1;209(2):123-33. doi: 10.1016/j.taap.2005.03.015.
• [27] Estrogens and human papilloma virus oncogenes regulate human ether--go-go-1 potassium channel expression. Cancer Res. 2009 Apr 15;69(8):3300-7. doi: 10.1158/0008-5472.CAN-08-2036. Epub 2009 Apr 7.
• [28] Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer. J Mol Endocrinol. 2009 Feb;42(2):87-103. doi: 10.1677/JME-08-0076. Epub 2008 Nov 4.
• [29] Estradiol attenuates EGF-induced rapid uPAR mobilization and cell migration via the G-protein-coupled receptor 30 in ovarian cancer cells. Int J Gynecol Cancer. 2009 Feb;19(2):214-22. doi: 10.1111/IGC.0b013e31819bcb75.
• [30] Antiestrogens induce transforming growth factor beta-mediated immunosuppression in breast cancer. Cancer Res. 2010 Feb 15;70(4):1314-22. doi: 10.1158/0008-5472.CAN-09-3292. Epub 2010 Feb 9.
• [31] Differential effects of estrogen receptor antagonists on pituitary lactotroph proliferation and prolactin release. Mol Cell Endocrinol. 2005 Jul 15;239(1-2):27-36. doi: 10.1016/j.mce.2005.04.008.
• [32] ERE-independent ERalpha target genes differentially expressed in human breast tumors. Mol Cell Endocrinol. 2005 Dec 21;245(1-2):53-9. doi: 10.1016/j.mce.2005.10.003. Epub 2005 Nov 17.
• [33] Cross-talk between non-genomic and genomic signalling pathways--distinct effect profiles of environmental estrogens. Toxicol Appl Pharmacol. 2010 Jun 1;245(2):160-70. doi: 10.1016/j.taap.2010.02.015. Epub 2010 Mar 4.
• [34] Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation. Int J Cancer. 2004 Mar 20;109(2):167-73. doi: 10.1002/ijc.11720.
• [35] Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex. Br J Cancer. 2013 Nov 12;109(10):2751-62. doi: 10.1038/bjc.2013.583. Epub 2013 Oct 29.
• [36] Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer. Endocr Relat Cancer. 2011 Apr 28;18(3):333-45. doi: 10.1530/ERC-10-0262. Print 2011 Jun.
• [37] Effects of the environmental estrogens bisphenol A, o,p'-DDT, p-tert-octylphenol and coumestrol on apoptosis induction, cell proliferation and the expression of estrogen sensitive molecular parameters in the human breast cancer cell line MCF-7. J Steroid Biochem Mol Biol. 2002 Jan;80(1):61-70. doi: 10.1016/s0960-0760(01)00173-x.
• [38] Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. Mol Endocrinol. 2010 May;24(5):969-80. doi: 10.1210/me.2009-0148. Epub 2010 Mar 8.
• [39] Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells. J Steroid Biochem Mol Biol. 2010 Feb 28;118(4-5):219-30. doi: 10.1016/j.jsbmb.2009.09.018. Epub 2009 Oct 6.
• [40] Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity. Toxicology. 2014 Jun 5;320:46-55. doi: 10.1016/j.tox.2014.03.007. Epub 2014 Mar 28.
• [41] Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. PLoS One. 2010 Jun 8;5(6):e11011. doi: 10.1371/journal.pone.0011011.
• [42] The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells. Breast Cancer Res. 2010;12(3):R43. doi: 10.1186/bcr2598. Epub 2010 Jun 28.
• [43] Inhibition of estrogen receptor reduces connexin 43 expression in breast cancers. Toxicol Appl Pharmacol. 2018 Jan 1;338:182-190. doi: 10.1016/j.taap.2017.11.020. Epub 2017 Nov 24.
• [44] Estrogen receptor regulates E2F1 expression to mediate tamoxifen resistance. Mol Cancer Res. 2010 Mar;8(3):343-52. doi: 10.1158/1541-7786.MCR-09-0395. Epub 2010 Mar 9.
• [45] Estrogen and pure antiestrogen fulvestrant (ICI 182 780) augment cell-matrigel adhesion of MCF-7 breast cancer cells through a novel G protein coupled estrogen receptor (GPR30)-to-calpain signaling axis. Toxicol Appl Pharmacol. 2014 Mar 1;275(2):176-81. doi: 10.1016/j.taap.2014.01.005. Epub 2014 Jan 17.
• [46] Expression and mitogenic effect of fibroblast growth factor-9 in human endometriotic implant is regulated by aberrant production of estrogen. J Clin Endocrinol Metab. 2003 Nov;88(11):5547-54. doi: 10.1210/jc.2003-030597.
• [47] Gestational bisphenol A exposure induces fatty liver development in male offspring mice through the inhibition of HNF1b and upregulation of PPAR. Cell Biol Toxicol. 2021 Feb;37(1):65-84. doi: 10.1007/s10565-020-09535-3. Epub 2020 Jul 4.
• [48] Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15081-6. doi: 10.1073/pnas.1009575107. Epub 2010 Aug 9.
• [49] Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015 Jun 19;290(25):15799-15811. doi: 10.1074/jbc.M115.641167. Epub 2015 May 11.
• [50] Methylparaben stimulates tumor initiating cells in ER+ breast cancer models. J Appl Toxicol. 2017 Apr;37(4):417-425. doi: 10.1002/jat.3374. Epub 2016 Sep 1.
• [51] The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium. Endocrinology. 2005 Mar;146(3):1066-73. doi: 10.1210/en.2004-1304. Epub 2004 Nov 24.
• [52] FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy. Cancer Res. 2010 Feb 1;70(3):1090-100. doi: 10.1158/0008-5472.CAN-09-2515. Epub 2010 Jan 26.
• [53] Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin. Breast Cancer Res. 2010;12(3):R32. doi: 10.1186/bcr2586. Epub 2010 Jun 4.
• [54] ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer. Nat Genet. 2020 Feb;52(2):198-207. doi: 10.1038/s41588-019-0554-0. Epub 2020 Jan 13.
• [55] Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma. Oncogene. 2010 Jun 3;29(22):3228-40. doi: 10.1038/onc.2010.71. Epub 2010 Mar 22.
• [56] CRK7 modifies the MAPK pathway and influences the response to endocrine therapy. Carcinogenesis. 2009 Oct;30(10):1696-701. doi: 10.1093/carcin/bgp187. Epub 2009 Aug 3.
• [57] Thymidylate synthase pharmacogenetics. Invest New Drugs. 2005 Dec;23(6):533-7. doi: 10.1007/s10637-005-4021-7.
• [58] The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
• [59] Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis Res Ther. 2009;11(1):R15.
• [60] UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate. Biochem Pharmacol. 2011 Jan 1;81(1):60-70.
• [61] Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. Tumour Biol. 2011 Oct;32(5):965-76.
• [62] Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014 Jan;66(1):15-23.
• [63] Methotrexate modulates folate phenotype and inflammatory profile in EA.hy 926 cells. Eur J Pharmacol. 2014 Jun 5;732:60-7.
• [64] Proteomic identification of differentially expressed proteins associated with the multiple drug resistance in methotrexate-resistant human breast cancer cells. Int J Oncol. 2014 Jul;45(1):448-58.
• [65] Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling. Mutat Res. 2007 Jun 1;619(1-2):16-29. doi: 10.1016/j.mrfmmm.2006.12.007. Epub 2007 Feb 8.
• [66] Effects of methotrexate on vascular endothelial growth factor, angiopoietin 1, and angiopoietin 2 in nasal polyps. Am J Rhinol Allergy. 2011 Jul-Aug;25(4):e129-32. doi: 10.2500/ajra.2011.25.3618.
• [67] Folate deficiency in normal human fibroblasts leads to altered expression of genes primarily linked to cell signaling, the cytoskeleton and extracellular matrix. J Nutr Biochem. 2007 Aug;18(8):541-52. doi: 10.1016/j.jnutbio.2006.11.002. Epub 2007 Feb 22.
• [68] Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation. Ann Rheum Dis. 2016 Feb;75(2):439-48. doi: 10.1136/annrheumdis-2014-206305. Epub 2015 Jan 9.
• [69] Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. J Biomol Screen. 2007 Apr;12(3):328-40. doi: 10.1177/1087057107299261. Epub 2007 Mar 22.
• [70] Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. Biomed Res Int. 2014;2014:616025. doi: 10.1155/2014/616025. Epub 2014 May 19.
• [71] Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells. Arch Toxicol. 2021 May;95(5):1631-1645. doi: 10.1007/s00204-021-03014-2. Epub 2021 Mar 26.
• [72] Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations. Int J Cancer. 2006 Apr 1;118(7):1699-712. doi: 10.1002/ijc.21570.
• [73] Microarray-based detection and expression analysis of extracellular matrix proteins in drug?resistant ovarian cancer cell lines. Oncol Rep. 2014 Nov;32(5):1981-90. doi: 10.3892/or.2014.3468. Epub 2014 Sep 9.
• [74] ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
• [75] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1213).
• [76] Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in chinese hamster ovary cells. J Biol Chem. 1998 Apr 3;273(14):8106-11.
• [77] Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32.
• [78] Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models. Drug Metab Dispos. 2011 Nov;39(11):2155-61.
• [79] Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade. Cancer Lett. 2016 Jan 1;370(1):153-64.
• [80] Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res. 2003 Sep 1;63(17):5538-43.
• [81] Transport of organic anions across the basolateral membrane of proximal tubule cells. Rev Physiol Biochem Pharmacol. 2003;146:95-158.
• [82] Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo. Mol Pharm. 2015 Dec 7;12(12):4259-69.
• [83] Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. Biochemistry. 2003 May 13;42(18):5429-37.
• [84] Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport. J Pharmacol Exp Ther. 2007 Jan;320(1):229-35.
• [85] The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates. Cancer Res. 2005 May 15;65(10):4425-30.
• [86] Transport of aminopterin by human organic anion transporters hOAT1 and hOAT3: Comparison with methotrexate. Drug Metab Pharmacokinet. 2010;25(2):163-9.
• [87] Methotrexate-loxoprofen interaction: involvement of human organic anion transporters hOAT1 and hOAT3. Drug Metab Pharmacokinet. 2004 Oct;19(5):369-74.
• [88] Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J Pharmacol Exp Ther. 2002 Aug;302(2):666-71.
• [89] Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants. J Pharmacol Exp Ther. 2006 Aug;318(2):521-9.
• [90] LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology. 2001 Jun;120(7):1689-99.
• [91] ABCC11/MRP8 confers pemetrexed resistance in lung cancer. Cancer Sci. 2010 Nov;101(11):2404-10.
• [92] Biology of the major facilitative folate transporters SLC19A1 and SLC46A1. Curr Top Membr. 2014;73:175-204.
• [93] Site-specific contribution of proton-coupled folate transporter/haem carrier protein 1 in the intestinal absorption of methotrexate in rats. J Pharm Pharmacol. 2009 Jul;61(7):911-8.
• [94] Genetics of rheumatoid arthritis. Mayo Clin Proc. 2006 Jan;81(1):94-101.
• [95] The pharmacogenetics of methotrexate. Rheumatology (Oxford). 2007 Oct;46(10):1520-4.
• [96] Understanding and managing methotrexate nephrotoxicity. Oncologist. 2006 Jun;11(6):694-703.
• [97] Methotrexate normalizes up-regulated folate pathway genes in rheumatoid arthritis. Arthritis Rheum. 2013 Nov;65(11):2791-802.
• [98] Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells. BMC Med Genomics. 2008 Aug 11;1:35. doi: 10.1186/1755-8794-1-35.
• [99] Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells. Cell Physiol Biochem. 2007;20(6):967-76.
• [100] SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. Toxicol Sci. 2014 Nov;142(1):196-209. doi: 10.1093/toxsci/kfu162. Epub 2014 Aug 14.
• [101] The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line. Mol Cancer Ther. 2006 Feb;5(2):438-49. doi: 10.1158/1535-7163.MCT-05-0243.
• [102] P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate. Toxicol Appl Pharmacol. 2016 Sep 1;306:27-35. doi: 10.1016/j.taap.2016.06.030. Epub 2016 Jul 1.
• [103] Gene expression profiling of leukemia T-cells resistant to methotrexate and 7-hydroxymethotrexate reveals alterations that preserve intracellular levels of folate and nucleotide biosynthesis. Biochem Pharmacol. 2009 Apr 15;77(8):1410-7.
• [104] Methotrexate induction of human sulfotransferases in Hep G2 and Caco-2 cells. J Appl Toxicol. 2005 Sep-Oct;25(5):354-60.
• [105] Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1. Protein J. 2005 Feb;24(2):65-77.
• [106] Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug Metab Dispos. 2006 Oct;34(10):1742-8.
• [107] Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis Rheum. 2008 Dec;58(12):3675-83.
• [108] Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo. Mol Med. 2012 May 9;18:423-32.
• [109] Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance. Exp Cell Res. 2012 Jun 10;318(10):1146-59.
• [110] Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate. J Rheumatol. 2007 Sep;34(9):1817-22. Epub 2007 Aug 1.
• [111] Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kappaB, osteoprotegerin, and receptor activator of nuclear factor kappaB ligand. Arthritis Rheum. 2004 Dec;50(12):3831-43. doi: 10.1002/art.20637.
• [112] Distinct genetic profile in peripheral blood mononuclear cells of psoriatic arthritis patients treated with methotrexate and TNF-inhibitors. Clin Rheumatol. 2014 Dec;33(12):1815-21. doi: 10.1007/s10067-014-2807-8. Epub 2014 Oct 24.
• [113] Inflammation in methotrexate-induced pulmonary toxicity occurs via the p38 MAPK pathway. Toxicology. 2009 Feb 27;256(3):183-90. doi: 10.1016/j.tox.2008.11.016. Epub 2008 Nov 28.
• [114] Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness. J Rheumatol. 2010 Feb;37(2):246-56. doi: 10.3899/jrheum.090167. Epub 2009 Dec 15.
• [115] Development of an alternative zebrafish model for drug-induced intestinal toxicity. J Appl Toxicol. 2018 Feb;38(2):259-273. doi: 10.1002/jat.3520. Epub 2017 Oct 13.
• [116] Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937. Arthritis Res Ther. 2014 Jan 20;16(1):R17. doi: 10.1186/ar4444.
• [117] [Increased secretion of vasopressin and edema formation in high dosage methotrexate therapy]. Z Gesamte Inn Med. 1988 Aug 1;43(15):411-4.
• [118] Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate. Arthritis Rheum. 2004 Oct;50(10):3286-95. doi: 10.1002/art.20518.
• [119] Editor's Highlight: Modeling Compound-Induced Fibrogenesis In Vitro Using Three-Dimensional Bioprinted Human Liver Tissues. Toxicol Sci. 2016 Dec;154(2):354-367. doi: 10.1093/toxsci/kfw169. Epub 2016 Sep 7.
• [120] Association of cell cycle arrest with anticancer drug-induced epithelial-mesenchymal transition in alveolar epithelial cells. Toxicology. 2019 Aug 1;424:152231. doi: 10.1016/j.tox.2019.06.002. Epub 2019 Jun 4.
• [121] [Regulation mechanism of autophagy-related protein LC3 by c-Jun in methotrexate resistant human choriocarcinoma JEG-3 cells]. Zhonghua Fu Chan Ke Za Zhi. 2014 Jul;49(7):531-5.
• [122] Methotrexate-related response on human peripheral blood mononuclear cells may be modulated by the Ala16Val-SOD2 gene polymorphism. PLoS One. 2014 Oct 20;9(10):e107299. doi: 10.1371/journal.pone.0107299. eCollection 2014.
• [123] [Early neurotoxicity of high-dose of methotrexate and tetrahydrobiopterin deficiency]. Arch Fr Pediatr. 1991 Dec;48(10):719-22.
• [124] Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells. Clin Exp Immunol. 2007 May;148(2):288-95. doi: 10.1111/j.1365-2249.2007.03335.x. Epub 2007 Feb 7.
• [125] Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation. J Cell Biochem. 2006 Sep 1;99(1):146-55. doi: 10.1002/jcb.20908.
• [126] Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. Arthritis Res Ther. 2006;8(6):R169. doi: 10.1186/ar2078.
• [127] Topotecan and methotrexate alter expression of the apoptosis-related genes BCL2, FAS and BCL2L12 in leukemic HL-60 cells. Biol Chem. 2006 Dec;387(12):1629-33. doi: 10.1515/BC.2006.203.
• [128] The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces. Br J Haematol. 2003 Jan;120(2):315-24. doi: 10.1046/j.1365-2141.2003.03971.x.
• [129] Enhancement of methotrexate nephrotoxicity after cisplatin therapy. Cancer. 1986 Dec 15;58(12):2617-21. doi: 10.1002/1097-0142(19861215)58:12<2617::aid-cncr2820581211>3.0.co;2-b.
• [130] Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2. Biochem Pharmacol. 2011 Feb 15;81(4):510-7. doi: 10.1016/j.bcp.2010.11.014. Epub 2010 Nov 27.
• [131] Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity. Cell Biol Toxicol. 2021 Apr;37(2):151-175. doi: 10.1007/s10565-020-09537-1. Epub 2020 Jun 14.
• [132] Increased matrix proteins, collagen and transforming growth factor are early markers of hepatotoxicity in patients on long-term methotrexate therapy. J Toxicol Clin Toxicol. 1996;34(3):301-5. doi: 10.3109/15563659609013794.
• [133] A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate. Cancer Gene Ther. 2008 Sep;15(9):576-90. doi: 10.1038/cgt.2008.28. Epub 2008 May 16.
• [134] Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action. Arthritis Res Ther. 2012 Jun 8;14(3):R138. doi: 10.1186/ar3871.
• [135] The influence of methotrexate on the gene expression of the pro-inflammatory cytokine IL-12A in the therapy of rheumatoid arthritis. Clin Exp Rheumatol. 2011 Nov-Dec;29(6):963-9. Epub 2011 Dec 22.
• [136] Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis. Mol Immunol. 2009 Oct;46(16):3345-57. doi: 10.1016/j.molimm.2009.07.019. Epub 2009 Sep 3.
• [137] The in vitro and in vivo anti-tumor effects of MTX-Fe3O 4-PLLA-PEG-PLLA microspheres prepared by suspension-enhanced dispersion by supercritical CO2. Sci China Life Sci. 2014 Jul;57(7):698-709. doi: 10.1007/s11427-014-4680-8. Epub 2014 Jun 16.
• [138] Methotrexate increases expression of cell cycle checkpoint genes via JNK activation. Arthritis Rheum. 2012 Jun;64(6):1780-9. doi: 10.1002/art.34342. Epub 2011 Dec 19.
• [139] Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone. Eur J Pharmacol. 2005 Dec 28;528(1-3):27-36. doi: 10.1016/j.ejphar.2005.10.068.
• [140] [Expression and function of Ahi-1 gene in Jurkat cells]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Apr;17(2):445-9.
• [141] Effect of doxorubicin, oxaliplatin, and methotrexate administration on the transcriptional activity of BCL-2 family gene members in stomach cancer cells. Cancer Biol Ther. 2013 Jul;14(7):587-96. doi: 10.4161/cbt.24591. Epub 2013 May 10.
• [142] Networking of differentially expressed genes in human cancer cells resistant to methotrexate. Genome Med. 2009 Sep 4;1(9):83. doi: 10.1186/gm83.
• [143] ZNRD1 mediates resistance of gastric cancer cells to methotrexate by regulation of IMPDH2 and Bcl-2. Biochem Cell Biol. 2006 Apr;84(2):199-206. doi: 10.1139/o05-173.
• [144] MTX-induced white matter changes are associated with polymorphisms of methionine metabolism. Neurology. 2005 Mar 8;64(5):912-3. doi: 10.1212/01.WNL.0000152840.26156.74.
• [145] Differential gene expression profiles may differentiate responder and nonresponder patients with rheumatoid arthritis for methotrexate (MTX) monotherapy and MTX plus tumor necrosis factor inhibitor combined therapy. J Rheumatol. 2012 Aug;39(8):1524-32. doi: 10.3899/jrheum.120092. Epub 2012 Jul 1.
• [146] KRAS mutation status is associated with enhanced dependency on folate metabolism pathways in non-small cell lung cancer cells. Mol Cancer Ther. 2014 Jun;13(6):1611-24. doi: 10.1158/1535-7163.MCT-13-0649. Epub 2014 Mar 31.
• [147] Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth. Ann Hematol. 2014 Mar;93(3):485-492. doi: 10.1007/s00277-013-1939-2. Epub 2013 Oct 24.
• [148] Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia. Mol Cancer Ther. 2006 Aug;5(8):1986-94.
• [149] Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis. Am J Hematol. 2011 Jan;86(1):98-101. doi: 10.1002/ajh.21897.
• [150] Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. BMC Cancer. 2010 Jun 1;10:250. doi: 10.1186/1471-2407-10-250.
• [151] Proteomics study of open biopsy samples identifies peroxiredoxin 2 as a predictive biomarker of response to induction chemotherapy in osteosarcoma. J Proteomics. 2013 Oct 8;91:393-404. doi: 10.1016/j.jprot.2013.07.022. Epub 2013 Aug 2.
• [152] A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis Rheum. 2007 Jun;56(6):1765-75. doi: 10.1002/art.22640.
• [153] The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells. PLoS One. 2013 May 13;8(5):e63276. doi: 10.1371/journal.pone.0063276. Print 2013.
• [154] [Expression of C1QBP gene and its correlation with drug resistance in human resistance choriocarcinoma cell line]. Zhonghua Fu Chan Ke Za Zhi. 2014 Aug;49(8):616-20.
• [155] Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032.
• [156] A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. J Biol Chem. 2017 Mar 24;292(12):4873-4884.
• [157] Methylenetetrahydrofolate reductase C677T and A1298C gene variants in adult non-Hodgkin's lymphoma patients: association with toxicity and survival. Haematologica. 2007 Apr;92(4):478-85. doi: 10.3324/haematol.10587.
• [158] Associations of novel genetic variations in the folate-related and ARID5B genes with the pharmacokinetics and toxicity of high-dose methotrexate in paediatric acute lymphoblastic leukaemia. Br J Haematol. 2014 Aug;166(3):410-20.
• [159] Nicotinamide Phosphoribosyltransferase Attenuates Methotrexate Response in Juvenile Idiopathic Arthritis and In Vitro. Clin Transl Sci. 2016 Jun;9(3):149-57. doi: 10.1111/cts.12399. Epub 2016 May 11.
• [160] Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.