Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUN54G)

Drug Name
AMINOHIPPURIC ACID Drug Info
Synonyms
4-Aminohippuric acid; aminohippuric acid; 61-78-9; P-AMINOHIPPURIC ACID; Paha; Glycine, N-(4-aminobenzoyl)-; N-(4-Aminobenzoyl)glycine; para-Aminohippuric acid; Nefrotest; 2-(4-aminobenzamido)acetic acid; N-(p-Aminobenzoyl)glycine; p-Aminohippurate; Aminohippurate; PAH (amino acid); 4-Amino hippuric acid; N-(para-aminobenzoyl)glycine; Hippuric acid, p-amino-; N-(p-Aminobenzoyl)aminoacetic acid; para-Aminohippurate; paraaminohippuric acid; PAH; UNII-Y79XT83BJ9; NSC 13064; HSDB 2139; 4-Aminobenzoyl Glycine; EINECS 200-518-9
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
2148
ChEBI ID
CHEMBL463
CAS Number
CAS 61-78-9
TTD Drug ID
DMUN54G
VARIDT Drug ID
DR00067

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Solute carrier family 22 member 8 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
FLUORESCEIN DMQTFAO Ocular disease 1F00.1Z Approved [2]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [15]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [2]
GLUTARATE DMPUFDS Discovery agent N.A. Investigative [2]
ADIPATE DM2XI09 Discovery agent N.A. Investigative [2]
HEPTANOATE DMGEO8N Discovery agent N.A. Investigative [2]
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Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [16]
Methotrexate DM2TEOL Anterior urethra cancer Approved [17]
Folic Acid DMEMBJC Colorectal carcinoma Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [19]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [20]
Verapamil DMA7PEW Angina pectoris BA40 Approved [21]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [22]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [23]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [24]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [25]
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Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Folic Acid DMEMBJC Colorectal carcinoma Approved [28]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [32]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [33]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [34]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [35]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Multidrug resistance-associated protein 4 (ABCC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [36]
Folic Acid DMEMBJC Colorectal carcinoma Approved [37]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [38]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [39]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [21]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [40]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [41]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [42]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [43]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [21]
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Drug(s) Transported By Organic anion transporter 1 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [45]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [46]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [47]
Aciclovir DMYLOVR Genital herpes 1A94 Approved [47]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [47]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [48]
Olmesartan medoxomil DMWBHRY High blood pressure BA00 Approved [49]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [50]
FLUORESCEIN DMQTFAO Ocular disease 1F00.1Z Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Organic anion transporter 3 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [46]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [47]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [10]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [53]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [54]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [55]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [56]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [57]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [58]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [77]
Methotrexate DM2TEOL Anterior urethra cancer Approved [78]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [79]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [10]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [80]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [80]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [81]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [81]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [82]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [83]
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Drug(s) Transported By Organic anion transporting polypeptide 1A2 (SLCO1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [59]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [60]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [61]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [62]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [56]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [63]
Saquinavir DMG814N Human immunodeficiency virus infection 1C62 Approved [64]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [65]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [66]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [67]
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Drug(s) Transported By ATP-binding cassette sub-family A member 8 (ABCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estrone sulfate DMVBIZL Atrophic vaginitis GA30.2 Approved [4]
Sodium taurocholate DM3GO0J Type-2 diabetes 5A11 Phase 1/2 [4]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [4]
Drug(s) Transported By Sodium-dependent phosphate transport protein 4 (SLC17A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phosphate DMUXQG7 Constipation DD91.1 Approved [5]
Drug(s) Affected By ABC-type organic anion transporter ABCA8 (ABCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [71]
Indomethacin DMSC4A7 Bursitis Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [73]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [69]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [75]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aryl hydrocarbon receptor repressor (AHRR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [84]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Cotinine DMCEZ1B Insecticide N.A. Approved [87]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [88]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [89]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [91]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [70]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Secretory carrier-associated membrane protein 3 (SCAMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [96]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [97]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [98]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Pre-mRNA-processing factor 17 (CDC40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [101]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [102]
RESORCINOL DMM37C0 Discovery agent N.A. Investigative [103]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Annexin A1 (ANXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [109]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [110]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [111]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [112]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [113]
Fructose DM43AN2 Vomiting MD90 Approved [114]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [115]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [116]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [117]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Fyn (FYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ethanol DMDRQZU Chronic pain MG30 Approved [126]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [71]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [127]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [128]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [129]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [130]
Gefitinib DM15F0X Colon adenocarcinoma Approved [131]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [132]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [134]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [135]
Methotrexate DM2TEOL Anterior urethra cancer Approved [136]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [145]
Coprexa DMA0WEK Neurological disorder 6B60 Phase 3 [146]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [147]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Lyn (LYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [151]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [152]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [153]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [155]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [156]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [157]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [158]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [116]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [160]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [162]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 6 (FGF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Arsenic DMTL2Y1 N. A. N. A. Approved [164]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [165]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [166]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-2 (ATF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [168]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [171]
Bortezomib DMNO38U Leukemia Approved [172]
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Drug(s) Affected By Methylated-DNA--protein-cysteine methyltransferase (MGMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [173]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [124]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [174]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [175]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [176]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [177]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [178]
Topotecan DMP6G8T Central nervous system neoplasm Approved [179]
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Drug(s) Affected By Integrin beta-5 (ITGB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [180]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [180]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [180]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [163]
Quercetin DM3NC4M Obesity 5B81 Approved [141]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [182]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [183]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [184]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [184]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [185]
Ethanol DMDRQZU Chronic pain MG30 Approved [186]
Menthol DMG2KW7 Back pain ME84.Z Approved [187]
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Drug(s) Affected By Proteasome subunit beta type-1 (PSMB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [188]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [190]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [191]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [192]
Paclitaxel DMLB81S Breast carcinoma Approved [192]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Epinephrine DM3KJBC Acute asthma CA23 Approved [197]
Quercetin DM3NC4M Obesity 5B81 Approved [198]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [199]
Fructose DM43AN2 Vomiting MD90 Approved [200]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit alpha type-1 (PSMA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [202]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [151]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [203]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Benzatropine DMF7EXL Parkinsonian disorder Approved [204]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [205]
NVP-AUY922 DMTYXQF Multiple myeloma 2A83 Phase 2 [206]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [207]
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Drug(s) Affected By Protein S100-A4 (S100A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [208]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [151]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [210]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [211]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [212]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [213]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [214]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [215]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [216]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [217]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [218]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [219]
Gefitinib DM15F0X Colon adenocarcinoma Approved [220]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aryl hydrocarbon receptor nuclear translocator (ARNT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Methotrexate DM2TEOL Anterior urethra cancer Approved [167]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [224]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [225]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [226]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [227]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [228]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit alpha type-5 (PSMA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [229]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [151]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [230]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [231]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Menthol DMG2KW7 Back pain ME84.Z Approved [187]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [205]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-5 (PSMB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [151]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Sibutramine DMFJTDI Obesity 5B81 Approved [232]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [233]
Bortezomib DMNO38U Leukemia Approved [234]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [235]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
WP-1066 DMUGHWR Recurrent glioblastoma 2A00.00 Phase 1/2 [235]
MG-132 DMKA2YS N. A. N. A. Preclinical [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [237]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [214]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [238]
Paclitaxel DMLB81S Breast carcinoma Approved [239]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [240]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [213]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [114]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [241]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [216]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-12 subunit alpha (IL12A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [242]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [243]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [244]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [245]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [246]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [247]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [88]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [128]
Arsenic DMTL2Y1 N. A. N. A. Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 9 (FGF9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [249]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Panobinostat DM58WKG Chronic graft versus host disease Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [250]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [251]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [252]
Arsenic DMTL2Y1 N. A. N. A. Approved [91]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [253]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome regulatory subunit 7 (PSMC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [254]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [255]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [256]
Arsenic DMTL2Y1 N. A. N. A. Approved [91]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [257]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [258]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Gefitinib DM15F0X Colon adenocarcinoma Approved [259]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [132]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Etretinate DM2CZFA Keratosis ED56 Approved [260]
Prednisone DM2HG4X Acute asthma CA23 Approved [261]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [262]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [263]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-alpha-acetyltransferase 10 (NAA10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Clozapine DMFC71L Schizophrenia 6A20 Approved [204]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [247]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [171]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [96]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [264]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [115]
Gefitinib DM15F0X Colon adenocarcinoma Approved [265]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [266]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [267]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [268]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [269]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [120]
Ethacrynic acid DM60QMR Edema MG29 Approved [270]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 9 (MAPK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [271]
Quercetin DM3NC4M Obesity 5B81 Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [273]
Sorbitol DMAN0DE Constipation DD91.1 Approved [274]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [276]
Quercetin DM3NC4M Obesity 5B81 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [277]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Menthol DMG2KW7 Back pain ME84.Z Approved [187]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [278]
Indomethacin DMSC4A7 Bursitis Approved [279]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-3 (PSMB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [281]
Testosterone DM7HUNW Hot flushes GA30 Approved [277]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [139]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [282]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [283]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome non-ATPase regulatory subunit 4 (PSMD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [97]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [284]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [96]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome regulatory subunit 4 (PSMC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [93]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Benzatropine DMF7EXL Parkinsonian disorder Approved [204]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [285]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [93]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [283]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [96]
MG-132 DMKA2YS N. A. N. A. Preclinical [286]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor NF-kappa-B p100 subunit (NFKB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [241]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [117]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [181]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [287]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [288]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [289]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [290]
Diazepam DM08E9O Alcohol withdrawal Approved [291]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [292]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [290]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [290]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [293]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [294]
Ethacrynic acid DM60QMR Edema MG29 Approved [292]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [290]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 1 (SRSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [295]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Selenium DM25CGV N. A. N. A. Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Leflunomide DMR8ONJ Arthritis FA20 Approved [296]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Folic Acid DMEMBJC Colorectal carcinoma Approved [297]
Bortezomib DMNO38U Leukemia Approved [172]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FAS-associated death domain protein (FADD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [298]
Selenium DM25CGV N. A. N. A. Approved [299]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [276]
Quercetin DM3NC4M Obesity 5B81 Approved [300]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [181]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [301]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [302]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [303]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [231]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [174]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-27 subunit beta (EBI3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [304]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [305]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [143]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [127]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [306]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [307]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Splicing factor 3B subunit 3 (SF3B3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [308]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Benzatropine DMF7EXL Parkinsonian disorder Approved [204]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [73]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [285]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 7 (SRSF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [254]
Selenium DM25CGV N. A. N. A. Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [310]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [311]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Clozapine DMFC71L Schizophrenia 6A20 Approved [204]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [171]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [312]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [74]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [282]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [96]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [98]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By PHD finger-like domain-containing protein 5A (PHF5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [310]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Folic Acid DMEMBJC Colorectal carcinoma Approved [313]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [314]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [315]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [316]
Milchsaure DM462BT Pruritus EC90 Investigative [317]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [318]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pre-mRNA-splicing factor 38A (PRPF38A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [319]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [319]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [283]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [320]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [321]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By 26S proteasome non-ATPase regulatory subunit 1 (PSMD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [203]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [311]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [247]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [100]
Arsenic DMTL2Y1 N. A. N. A. Approved [91]
Lithium DMZ3OU6 Bipolar disorder 6A60 Phase 2 [322]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [283]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Forkhead box protein P3 (FOXP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [323]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [324]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [325]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [125]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [314]
GSK618334 DMJPXZ4 Drug abuse 6C4G.1Z Phase 1 [326]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [95]
Dorsomorphin DMKYXJW Discovery agent N.A. Investigative [327]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 22 member 11 (SLC22A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [328]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [328]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [71]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [328]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [328]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [329]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [328]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [330]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [328]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [331]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [332]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [333]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [334]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [335]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [336]
Quercetin DM3NC4M Obesity 5B81 Approved [337]
Testosterone DM7HUNW Hot flushes GA30 Approved [319]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [329]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 22 member 7 (SLC22A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [328]
Methotrexate DM2TEOL Anterior urethra cancer Approved [167]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [338]
Paclitaxel DMLB81S Breast carcinoma Approved [339]
Allopurinol DMLPAOB Gout FA25 Approved [339]
Bumetanide DMRV7H0 Congestive heart failure BD10 Approved [339]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [339]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [339]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [339]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione S-transferase Mu 3 (GSTM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [340]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [341]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [94]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [247]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [342]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [343]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [344]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [345]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [346]
Etretinate DM2CZFA Keratosis ED56 Approved [260]
Quercetin DM3NC4M Obesity 5B81 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [347]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [348]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [301]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [349]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [350]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Solute carrier family 22 member 8 (SLC22A8) TTTQR47 S22A8_HUMAN Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Sodium-dependent phosphate transport protein 3 (SLC17A2) DTRF4L3 NPT3_HUMAN Substrate [3]
ATP-binding cassette sub-family A member 8 (ABCA8) DT9NXMV ABCA8_HUMAN Substrate [4]
Sodium-dependent phosphate transport protein 4 (SLC17A3) DTFOJL7 NPT4_HUMAN Substrate [5]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [6]
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [7]
Organic anion transporting polypeptide 1A2 (SLCO1A2) DTE2B1D SO1A2_HUMAN Substrate [8]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [6]
Organic anion transporter 1 (SLC22A6) DTQ23VB S22A6_HUMAN Substrate [9]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [10]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) OTW258OV PSMD1_HUMAN Gene/Protein Processing [11]
26S proteasome non-ATPase regulatory subunit 4 (PSMD4) OTH1VZTM PSMD4_HUMAN Gene/Protein Processing [11]
26S proteasome regulatory subunit 4 (PSMC1) OTLHD56E PRS4_HUMAN Gene/Protein Processing [11]
26S proteasome regulatory subunit 7 (PSMC2) OTJ4V337 PRS7_HUMAN Gene/Protein Processing [11]
ABC-type organic anion transporter ABCA8 (ABCA8) OTCWLX6N ABCA8_HUMAN Regulation of Drug Effects [4]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [11]
Alpha-taxilin OTO8XY5A TXLNA_HUMAN Gene/Protein Processing [12]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Gene/Protein Processing [12]
Aryl hydrocarbon receptor nuclear translocator (ARNT) OTMSIEZY ARNT_HUMAN Gene/Protein Processing [13]
Aryl hydrocarbon receptor repressor (AHRR) OTSJ12W6 AHRR_HUMAN Gene/Protein Processing [14]

References

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93 Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst. 2009 Mar 4;101(5):306-20.
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