Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5JVS3)

Drug Name
Isoniazid Drug Info
Synonyms
Abdizide; Andrazide; Anidrasona; Antimicina; Antituberkulosum; Armacide; Armazid; Armazide; Atcotibine; Azuren; Bacillen; Bacillin; Cedin; Cemidon; Chemiazid; Chemidon; Continazine; Cortinazine; Cotinazin; Cotinizin; Defonin; Dibutin; Diforin; Dinacrin; Ditubin; Ebidene; Eralon; Ertuban; Eutizon; Evalon; Fetefu; Fimalene; HIA; Hidranizil; Hidrasonil; Hidrulta; Hidrun; Hycozid; Hydra; Hydrazid; Hydrazide; Hyozid; Hyzyd; INH; Idrazil; Inah; Inizid; Iscotin; Isidrina; Ismazide; Isobicina; Isocid; Isocidene; Isocotin; Isohydrazide; Isokin; Isolyn; Isonerit; Isonex; Isoniacid; Isoniazida; Isoniazide; Isoniazidum; Isonicazide; Isonicid; Isonico; Isonicotan; Isonicotil; Isonicotinhydrazid; Isonicotinohydrazide; Isonide; Isonidrin; Isonikazid; Isonilex; Isonin; Isonindon; Isonirit; Isoniton; Isonizida; Isonizide; Isotamine; Isotebe; Isotebezid; Isotinyl; Isozid; Isozide; Isozyd; LANIZID; Laniazid; Laniozid; Mybasan; Neoteben; Neoxin; Neumandin; Nevin; Niadrin; Nicazide; Nicetal; Nicizina; Niconyl; Nicotibina; Nicotibine; Nicotisan; Nicozide; Nidaton; Nidrazid; Nikozid; Niplen; Nitadon; Niteban; Nydrazid; Nyscozid; Pelazid; Percin; Phthisen; Pycazide; Pyreazid; Pyricidin; Pyridicin; Pyrizidin; Raumanon; Razide; Retozide; Rimicid; Rimifon; Rimiphone; Rimitsid; Robiselin; Robisellin; Roxifen; Sanohidrazina; Sauterazid; Sauterzid; Stanozide; Tebecid; Tebemid; Tebenic; Tebexin; Tebilon; Tebos; Teebaconin; Tekazin; Tibazide; Tibemid; Tibiazide; Tibinide; Tibison; Tibivis; Tibizide; Tibusan; Tisin; Tisiodrazida; Tizide; Tubazid; Tubazide; Tubeco; Tubecotubercid; Tubercid; Tuberian; Tubicon; Tubilysin; Tubizid; Tubomel; Tyvid; Unicocyde; Unicozyde; Vazadrine; Vederon; Zidafimia; Zinadon; Zonazide; Hid rasonil; Isoco tin; Isoniazid SA; Isozid e; Nidra zid; Rimif on; BP 5015; Bp 5 015; FSR 3; I0138; INHd20; L 1945; Nitebannsc 9659; Preparation 6424; RP 5015; AZT + Isoniazid; Cedin (Aerosol); Dow-Isoniazid; FRS-3; FSR-3; Ido-tebin; In-73; Inh-Burgthal; Isoniazid & EEP; Isoniazid & Propolis; Laniazid (TN); Neo-Tizide; Nydrazid (TN); RP-5015; TB-Phlogin; TB-Razide; TB-Vis; Usaf cb-2; I.A.I; RU-EF-Tb; RY-EF-Tb; I.A.I.
Indication
Disease Entry ICD 11 Status REF
Latent tuberculosis infection Approved [1]
Pulmonary tuberculosis 1B10.Z Approved [1]
Tuberculosis 1B10-1B1Z Approved [2]
Therapeutic Class
Antitubercular Agents
Cross-matching ID
PubChem CID
3767
ChEBI ID
CHEBI:6030
CAS Number
CAS 54-85-3
TTD Drug ID
DM5JVS3
VARIDT Drug ID
DR00422
INTEDE Drug ID
DR0886
ACDINA Drug ID
D00332

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial Fatty acid synthetase I (Bact inhA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [15]
Ethionamide DM8K3EI Pulmonary tuberculosis 1B10.Z Approved [16]
Prothionamide DMX0EZJ Tuberculosis 1B10-1B1Z Approved [16]
AFN-1720 DM6AJKC Bacterial infection 1A00-1C4Z Phase 2 [17]
MMV00/0053 DMF27BS Malaria 1F40-1F45 Terminated [18]
Nicotinamide-Adenine-Dinucleotide DM9LRKB N. A. N. A. Investigative [19]
Beta-D-Glucose DM5IHYP Discovery agent N.A. Investigative [19]
2-Hexadecynoic acid DMTFIPZ Discovery agent N.A. Investigative [20]
4-(2-Thienyl)-1-(4-Methylbenzyl)-1h-Imidazole DMX681M Discovery agent N.A. Investigative [19]
Indole Naphthyridinone DMB4ZNW Discovery agent N.A. Investigative [19]
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Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [21]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [23]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [24]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
Estrone DM5T6US Acne vulgaris ED80 Approved [28]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [29]
Ethanol DMDRQZU Chronic pain MG30 Approved [30]
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Drug(s) Affected By Alanine aminotransferase 1 (GPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [32]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [31]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [31]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [31]
Gefitinib DM15F0X Colon adenocarcinoma Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [33]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [33]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [35]
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Drug(s) Affected By N-alpha-acetyltransferase 20 (NAA20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [37]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [38]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [40]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [31]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [31]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [31]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [41]
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Drug(s) Affected By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [42]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [43]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [42]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [43]
Sulfinpyrazone DMEV954 Gout FA25 Approved [44]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [42]
Zafirlukast DMHNQOG Asthma CA23 Approved [42]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [42]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [45]
Dabrafenib DMX6OE3 Melanoma 2C30 Approved [46]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [48]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [49]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [50]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [48]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Fluoxetine DM3PD2C Bipolar depression Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [49]
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Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [48]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [50]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [48]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Fluoxetine DM3PD2C Bipolar depression Approved [48]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [49]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [48]
Panobinostat DM58WKG Chronic graft versus host disease Approved [54]
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Drug(s) Affected By Protein DEPP1 (DEPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [48]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [49]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [48]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Fluoxetine DM3PD2C Bipolar depression Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [49]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [48]
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Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [59]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [60]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [62]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [65]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [66]
Fructose DM43AN2 Vomiting MD90 Approved [31]
Ketoprofen DMRKXPT Bursitis Approved [31]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [69]
Gefitinib DM15F0X Colon adenocarcinoma Approved [70]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [71]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [72]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [73]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [75]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [81]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [82]
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Drug(s) Affected By C-X-C motif chemokine 10 (CXCL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [90]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [91]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [92]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [93]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [94]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [72]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [95]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [96]
Methotrexate DM2TEOL Anterior urethra cancer Approved [91]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [97]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [98]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [101]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [102]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [103]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [105]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [106]
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Drug(s) Affected By Interleukin-10 (IL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [108]
Methotrexate DM2TEOL Anterior urethra cancer Approved [109]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Bisoprolol DM3UZ95 Hypertension BA00-BA04 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [113]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [114]
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Drug(s) Affected By Interleukin-12 subunit alpha (IL12A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [116]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [117]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [39]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [118]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [119]
Arsenic DMTL2Y1 N. A. N. A. Approved [120]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
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Drug(s) Affected By Interleukin-12 subunit beta (IL12B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [122]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [116]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [123]
Capsaicin DMGMF6V Back pain ME84.Z Approved [124]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [125]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [126]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [127]
RGI-2001 DM4AC2F Graft-versus-host disease 4B24 Phase 2 [128]
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Drug(s) Affected By Interleukin-17A (IL17A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [78]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [129]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [130]
Ethanol DMDRQZU Chronic pain MG30 Approved [122]
Arsenic DMTL2Y1 N. A. N. A. Approved [131]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [132]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [133]
Apilimod dimesylate DM4N2O0 Non-hodgkin lymphoma 2B33.5 Phase 2 [134]
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Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [136]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Ethacrynic acid DM60QMR Edema MG29 Approved [137]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [138]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [97]
Leflunomide DMR8ONJ Arthritis FA20 Approved [139]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [97]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [97]
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Drug(s) Affected By Gamma-butyrobetaine dioxygenase (BBOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [142]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [143]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [144]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [145]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [146]
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Drug(s) Affected By Alpha-fetoprotein (AFP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [8]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [147]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [149]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [150]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [151]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [152]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [153]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [154]
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Drug(s) Affected By Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Testosterone DM7HUNW Hot flushes GA30 Approved [156]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [156]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [38]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [158]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [159]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [160]
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Drug(s) Affected By Amyloid-beta precursor protein (APP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Selenium DM25CGV N. A. N. A. Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [163]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [136]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [167]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [168]
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Drug(s) Affected By Osteopontin (SPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [169]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [171]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [173]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [176]
Panobinostat DM58WKG Chronic graft versus host disease Approved [54]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
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Drug(s) Affected By Mucin-1 (MUC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [180]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [181]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [8]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Folic Acid DMEMBJC Colorectal carcinoma Approved [182]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [183]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [184]
Bortezomib DMNO38U Leukemia Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 14-3-3 protein sigma (SFN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [186]
Gefitinib DM15F0X Colon adenocarcinoma Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [188]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [190]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [191]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [189]
Panobinostat DM58WKG Chronic graft versus host disease Approved [54]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [192]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [194]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [195]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [196]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [197]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [198]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [199]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [200]
Methotrexate DM2TEOL Anterior urethra cancer Approved [201]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate--cysteine ligase regulatory subunit (GCLM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [202]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [180]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [204]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [205]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [206]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-2 (CLDN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [210]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [8]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [211]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [142]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [212]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [160]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [213]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [214]
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Drug(s) Affected By Large neutral amino acids transporter small subunit 1 (SLC7A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [215]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Selenium DM25CGV N. A. N. A. Approved [162]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [216]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [217]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [180]
Panobinostat DM58WKG Chronic graft versus host disease Approved [54]
Estrone DM5T6US Acne vulgaris ED80 Approved [215]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tribbles homolog 3 (TRIB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [138]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [204]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [138]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [60]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [218]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [219]
Leflunomide DMR8ONJ Arthritis FA20 Approved [139]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [162]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [220]
Panobinostat DM58WKG Chronic graft versus host disease Approved [54]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [51]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [152]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [38]
Ethanol DMDRQZU Chronic pain MG30 Approved [222]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protease serine 2 (TMPRSS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [13]
Diazepam DM08E9O Alcohol withdrawal Approved [13]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Selenium DM25CGV N. A. N. A. Approved [162]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [13]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [13]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [13]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [13]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [14]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [72]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [14]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [225]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Gefitinib DM15F0X Colon adenocarcinoma Approved [226]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [14]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [95]
Selenium DM25CGV N. A. N. A. Approved [227]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [228]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [160]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [31]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [230]
Diazepam DM08E9O Alcohol withdrawal Approved [231]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [232]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [147]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [233]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [234]
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Antileukoproteinase (SLPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [14]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [14]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [14]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [14]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [14]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [237]
Haloperidol DM96SE0 Delirium Approved [31]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [238]
Selenium DM25CGV N. A. N. A. Approved [239]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [240]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [241]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [242]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [243]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [244]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [245]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [246]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [31]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Verapamil DMA7PEW Angina pectoris BA40 Approved [247]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [248]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [249]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucose-6-phosphate 1-dehydrogenase (G6PD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [250]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [31]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [251]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [252]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [253]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [180]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [162]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [180]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [254]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [205]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [53]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ferrochelatase, mitochondrial (FECH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Selenium DM25CGV N. A. N. A. Approved [162]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [97]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [97]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [152]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [97]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [142]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [256]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [257]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [258]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [259]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [260]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [261]
Gefitinib DM15F0X Colon adenocarcinoma Approved [262]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [263]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [265]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [257]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [266]
Paclitaxel DMLB81S Breast carcinoma Approved [267]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [268]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [256]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [31]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [225]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [269]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [270]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [271]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [272]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [273]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [274]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [275]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [14]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [272]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [277]
Quercetin DM3NC4M Obesity 5B81 Approved [278]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [279]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [149]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [280]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [281]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [282]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [283]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [284]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [285]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [286]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [287]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [288]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [289]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [290]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [291]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [292]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [293]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [294]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [295]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [296]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [248]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [297]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [298]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [299]
Meloxicam DM2AR7L Arthritis FA20 Approved [300]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [301]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [302]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [243]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [294]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Verapamil DMA7PEW Angina pectoris BA40 Approved [247]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [303]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [297]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [304]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Meloxicam DM2AR7L Arthritis FA20 Approved [305]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [306]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-24 (IL24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [14]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [14]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [14]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [307]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [136]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [253]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [14]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [253]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear respiratory factor 1 (NRF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [308]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [309]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [62]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [310]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [311]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [312]
Arsenic DMTL2Y1 N. A. N. A. Approved [313]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [146]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [314]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Natural cytotoxicity triggering receptor 3 ligand 1 (NCR3LG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [316]
Testosterone DM7HUNW Hot flushes GA30 Approved [317]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [152]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [318]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [319]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [320]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [321]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [322]
Urethane DM7NSI0 N. A. N. A. Phase 4 [323]
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Drug(s) Affected By PTB-containing, cubilin and LRP1-interacting protein (PID1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [14]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [14]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [14]
Amikacin DM5PDRB Bacteremia 1A73 Approved [14]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [14]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [14]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Trihexyphenidyl DMB19L8 Dystonia 8A02 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-1 (SIRT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [264]
Selenium DM25CGV N. A. N. A. Approved [162]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [324]
Quercetin DM3NC4M Obesity 5B81 Approved [325]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [326]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [327]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [328]
Testosterone DM7HUNW Hot flushes GA30 Approved [317]
Olaparib DM8QB1D Ovarian cancer 2C73 Approved [329]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [36]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiotensin-converting enzyme 2 (ACE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Captopril DM458UM Chronic heart failure BD1Z Approved [330]
Diazepam DM08E9O Alcohol withdrawal Approved [13]
Dantrolene DM1D8XY Hyperthermia MG26 Approved [13]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [13]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [13]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [13]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [13]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [13]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [331]
Fructose DM43AN2 Vomiting MD90 Approved [332]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [333]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [334]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [335]
Leflunomide DMR8ONJ Arthritis FA20 Approved [139]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [335]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [336]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [337]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [338]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [339]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [340]
Quercetin DM3NC4M Obesity 5B81 Approved [341]
Testosterone DM7HUNW Hot flushes GA30 Approved [156]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [342]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [343]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eosinophil peroxidase (EPX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [175]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [318]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [345]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [346]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [175]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [347]
Butanoic Acid DMTAJP7 Discovery agent N.A. Investigative [348]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Myeloperoxidase (MPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dapsone DM4LT8A Acne vulgaris ED80 Approved [31]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [318]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [31]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [31]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [349]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [350]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [351]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [353]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [354]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [355]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [356]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [357]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [358]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [359]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [359]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [360]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [361]
Capsaicin DMGMF6V Back pain ME84.Z Approved [362]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [363]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione S-transferase Mu 1 (GSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [364]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [365]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [366]
Ethanol DMDRQZU Chronic pain MG30 Approved [367]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [253]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [253]
Methyldopa DM5I621 Hypertension BA00-BA04 Approved [368]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Testosterone DM7HUNW Hot flushes GA30 Approved [156]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [156]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Fatty acid synthetase I (Bact inhA) TTVTX4N INHA_MYCTU Inhibitor [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Substrate [4]
Catalase-peroxidase (katG) DEAGY5M KATG_SYNE7 Substrate [5]
Arylamine N-acetyltransferase (NAT) DEXCQTM A0A3P8LE58_TSUPA Substrate [6] , [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [8]
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS1) OTQY6ZSF HEM1_HUMAN Gene/Protein Processing [9]
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Gene/Protein Processing [10]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [11]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [12]
Alpha-fetoprotein (AFP) OT9GG3ZI FETA_HUMAN Gene/Protein Processing [8]
Amyloid-beta precursor protein (APP) OTKFD7R4 A4_HUMAN Gene/Protein Processing [8]
Angiotensin-converting enzyme 2 (ACE2) OTTRZGU7 ACE2_HUMAN Gene/Protein Processing [13]
Antileukoproteinase (SLPI) OTUNFUU8 SLPI_HUMAN Gene/Protein Processing [14]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [10]

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