Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ9WI4)

Drug Name
Nitrosoglutathione Drug Info
Synonyms
Glutathione thionitrite; Nitrosoglutathione; S-nitrosoglutathione; S-NITROSO-L-GLUTATHIONE; (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(nitrososulfanyl)ethyl]carbamoyl}butanoic acid; (S)-2-Amino-5-(((R)-1-((carboxymethyl)amino)-3-(nitrosothio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid; 57564-91-7; 78RRI89ZTO; BRN 3566211; C10H16N4O7S; CCRIS 2095; CHEBI:50091; Glycine, N-(N-L-gamma-glutamyl-S-nitroso-L-cysteinyl)-; N-(N-L-gamma-Glutamyl-S-nitroso-L-cysteinyl)glycine; SNOG; UNII-78RRI89ZTO; gsno
Cross-matching ID
PubChem CID
104858
ChEBI ID
CHEBI:50091
CAS Number
CAS 57564-91-7
TTD Drug ID
DMZ9WI4
INTEDE Drug ID
DR2448

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By S-(hydroxymethyl)glutathione dehydrogenase (adh)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitroprusside DMLUA2J Hypertension BA00-BA04 Approved [1]
Drug(s) Affected By Serine protease HTRA2, mitochondrial (HTRA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [9]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [12]
Testosterone DM7HUNW Hot flushes GA30 Approved [13]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [13]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [15]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [16]
Bortezomib DMNO38U Leukemia Approved [17]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [18]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [19]
Fructose DM43AN2 Vomiting MD90 Approved [20]
Ketoprofen DMRKXPT Bursitis Approved [20]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [22]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [23]
Gefitinib DM15F0X Colon adenocarcinoma Approved [24]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [27]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [28]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [34]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [35]
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Drug(s) Affected By C-X-C motif chemokine 10 (CXCL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [42]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
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Drug(s) Affected By Interleukin-5 (IL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [44]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [45]
Prednisone DM2HG4X Acute asthma CA23 Approved [46]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [47]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [49]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [51]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [52]
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Drug(s) Affected By Transcription factor Sp1 (SP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [20]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [58]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [59]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [60]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [62]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [63]
Verapamil DMA7PEW Angina pectoris BA40 Approved [64]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Selenium DM25CGV N. A. N. A. Approved [67]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [68]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [69]
Methotrexate DM2TEOL Anterior urethra cancer Approved [70]
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Drug(s) Affected By C-C motif chemokine 5 (CCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [71]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [72]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [73]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [74]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [75]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [76]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [77]
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Drug(s) Affected By Cystic fibrosis transmembrane conductance regulator (CFTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [78]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [81]
Miglustat DM5J64S Niemann-Pick disease type C Approved [82]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [83]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [80]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [84]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [84]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
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Drug(s) Affected By Interleukin-10 (IL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [86]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [45]
Methotrexate DM2TEOL Anterior urethra cancer Approved [87]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Bisoprolol DM3UZ95 Hypertension BA00-BA04 Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [91]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [39]
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Drug(s) Affected By Interleukin-12 subunit beta (IL12B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [39]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [92]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [94]
Capsaicin DMGMF6V Back pain ME84.Z Approved [95]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [96]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [97]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [98]
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Drug(s) Affected By T-lymphocyte activation antigen CD86 (CD86)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [3]
Kanamycin DM2DMPO Bacteremia 1A73 Approved [100]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [102]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [103]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [105]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [106]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [107]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [108]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [109]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [110]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [111]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [112]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [113]
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Drug(s) Affected By Transcription factor Sp3 (SP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [60]
Leflunomide DMR8ONJ Arthritis FA20 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Promegestone DMK4S8I Gynecological disease GA6Z Approved [116]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [118]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [119]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [120]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [121]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [123]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Gefitinib DM15F0X Colon adenocarcinoma Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [127]
Selenium DM25CGV N. A. N. A. Approved [128]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [129]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
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Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [131]
Prednisone DM2HG4X Acute asthma CA23 Approved [132]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [132]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [133]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [134]
Epinephrine DM3KJBC Acute asthma CA23 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
Fluoxetine DM3PD2C Bipolar depression Approved [137]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [138]
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Drug(s) Affected By Carbonyl reductase 1 (CBR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [139]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Testosterone enanthate DMB6871 N. A. N. A. Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [43]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [15]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [141]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [142]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [144]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [142]
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Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [145]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [147]
Etretinate DM2CZFA Keratosis ED56 Approved [148]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [149]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [150]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [151]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [152]
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Drug(s) Affected By Alcohol dehydrogenase class-3 (ADH5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [2]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [153]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Quercetin DM3NC4M Obesity 5B81 Approved [154]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [15]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [156]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [157]
Urethane DM7NSI0 N. A. N. A. Phase 4 [158]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
S-(hydroxymethyl)glutathione dehydrogenase (adh) Main DME DEAH3PE A0A0A7DS01_VIBCL Substrate [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alcohol dehydrogenase class-3 (ADH5) OTSO67MI ADHX_HUMAN Biotransformations [2]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Protein Interaction/Cellular Processes [3]
C-X-C motif chemokine 10 (CXCL10) OTTLQ6S0 CXL10_HUMAN Protein Interaction/Cellular Processes [3]
Carbonyl reductase 1 (CBR1) OTQ3A541 CBR1_HUMAN Biotransformations [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [5]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [5]
Cystic fibrosis transmembrane conductance regulator (CFTR) OT6B22QH CFTR_HUMAN Gene/Protein Processing [6]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Gene/Protein Processing [7]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Gene/Protein Processing [8]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Protein Interaction/Cellular Processes [3]

References

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2 The Janus face of alcohol dehydrogenase 3. Chem Biol Interact. 2009 Mar 16;178(1-3):29-35. doi: 10.1016/j.cbi.2008.10.050. Epub 2008 Nov 6.
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5 The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells. Toxicol Appl Pharmacol. 2010 May 1;244(3):374-84. doi: 10.1016/j.taap.2010.02.004. Epub 2010 Feb 11.
6 Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1. Biochem J. 2004 May 15;380(Pt 1):67-74. doi: 10.1042/BJ20031687.
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8 Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide. J Biol Chem. 2001 Oct 26;276(43):39805-11. doi: 10.1074/jbc.M107689200. Epub 2001 Aug 20.
9 Gingival Stromal Cells as an In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis. J Cell Biochem. 2017 Apr;118(4):819-828. doi: 10.1002/jcb.25757. Epub 2016 Nov 28.
10 Statin-triggered cell death in primary human lung mesenchymal cells involves p53-PUMA and release of Smac and Omi but not cytochrome c. Biochim Biophys Acta. 2010 Apr;1803(4):452-67. doi: 10.1016/j.bbamcr.2009.12.005. Epub 2010 Jan 4.
11 Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020 Nov 5;9(11):2423. doi: 10.3390/cells9112423.
12 Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicol Appl Pharmacol. 2012 Jun 1;261(2):204-16.
13 Effects of 1alpha,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells. Mol Cancer. 2011 May 18;10:58.
14 Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol. 2013 Jan;87(1):123-43.
15 Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. J Cell Physiol. 2021 Apr;236(4):2959-2975. doi: 10.1002/jcp.30055. Epub 2020 Sep 22.
16 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways. Biochem Pharmacol. 2012 Dec 15;84(12):1604-16. doi: 10.1016/j.bcp.2012.09.022. Epub 2012 Oct 5.
17 Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Res. 2005 Jul 15;65(14):6294-304. doi: 10.1158/0008-5472.CAN-05-0686.
18 Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells. J Biochem Mol Toxicol. 2020 Feb;34(2):e22433. doi: 10.1002/jbt.22433. Epub 2020 Jan 9.
19 A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations. Toxicol Appl Pharmacol. 2017 Nov 1;334:18-23. doi: 10.1016/j.taap.2017.08.017. Epub 2017 Sep 1.
20 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
21 CBD Promotes Oral Ulcer Healing via Inhibiting CMPK2-Mediated Inflammasome. J Dent Res. 2022 Feb;101(2):206-215. doi: 10.1177/00220345211024528. Epub 2021 Jul 16.
22 Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway. Toxicol Sci. 2014 Feb;137(2):404-15. doi: 10.1093/toxsci/kft254. Epub 2013 Nov 5.
23 Anti-inflammatory effects of the GABA(B) receptor agonist baclofen in allergic contact dermatitis. Exp Dermatol. 2010 Jul 1;19(7):661-6. doi: 10.1111/j.1600-0625.2010.01076.x. Epub 2010 Feb 25.
24 Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways. World J Gastrointest Oncol. 2022 Feb 15;14(2):450-477. doi: 10.4251/wjgo.v14.i2.450.
25 Sulfasalazine unveils a contact-independent HSV-TK/ganciclovir gene therapy bystander effect in malignant gliomas. Int J Oncol. 2007 Jan;30(1):283-90.
26 Oxidative Stress Alters miRNA and Gene Expression Profiles in Villous First Trimester Trophoblasts. Biomed Res Int. 2015;2015:257090. doi: 10.1155/2015/257090. Epub 2015 Aug 3.
27 Differential expression of microRNAs and their predicted targets in renal cells exposed to amphotericin B and its complex with copper (II) ions. Toxicol Mech Methods. 2017 Sep;27(7):537-543. doi: 10.1080/15376516.2017.1333554. Epub 2017 Jun 8.
28 Direct evidence for immunomodulatory properties of ribavirin on T-cell reactivity to hepatitis C virus. Antiviral Res. 2007 Jul;75(1):36-42. doi: 10.1016/j.antiviral.2006.11.008. Epub 2006 Dec 13.
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