Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMEN6X7)

Drug Name
Atropine Drug Info
Synonyms
dl-Hyoscyamine; Atropin; Atropen; dl-Tropyltropate; Atropinol; Atropina; Eyesules; Troyl tropate; Isopto-atropine; Atropin [German]; Atropina [Italian]; Atropin-flexiolen; (+,-)-Tropyl tropate; 51-55-8; DL-Tropyl tropate; Tropine, tropate (ester); Tropic acid, ester with tropine; Atropine sulfate; CCRIS 3080; Atropine (USP); Isopto Atropine; Tropic acid, 3-alpha-tropanyl ester; Atropt; HSDB 2199; DL-Tropanyl; Anaspaz; Atropair; Atrosulf; Belladenal; Cytospaz; Minims; Tropanol; Urised; Atropine Care; Atropine [BAN]; Atropinium cation; Hyoscyamine sulfate; Minims Atropine; OR22908; Atropen (TN); Bellergal-S; D1-hyoscyamine; Dl-Hyoscyamine; Dl-Tropyltropate; I-Tropine; NP-010662; Neo-Diophen; Ocu-Tropine; Protamine & Atropine; Atropinium(1+); Tropan-3alpha-ol; Tropan-3beta-ol; Atropine Sulfate SOP; DL-Tropanyl 2-hydroxy-1-phenylpropionate; Beta-Phenyl-gamma-oxypropionsaeure-tropyl-ester [German]; Beta-Phenyl-gamma-oxypropionsaure-tropyl-ester [German]; Tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate; Endo-8-methyl-8-azabicyclo[321]octan-3-ol; B eta-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[321]oct-3-yl ester; [(1R,5S)-8-methyl-8-azabicyclo[321]octan-3-yl] 3-hydroxy-2-phenylpropanoate; [(1S,5R)-8-methyl-8-azabicyclo[321]oct-3-yl] 3-hydroxy-2-phenyl-propanoate; Endo-(+/-)-alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[321]oct-3-yl ester; Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(321)oct-3-yl ester; (3-endo)-8-methyl-8-azabicyclo[321]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate; (3-endo)-8-methyl-8-azabicyclo[321]oct-3-yl 3-hydroxy-2-phenylpropanoate; (3-endo)-8-methyl-8-azabicyclo[321]oct-3-yl tropate; (3-endo)-8-methyl-8-azabicyclo[321]octan-3-ol; (3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azoniabicyclo[321]octane; (3-exo)-8-methyl-8-azabicyclo[321]octan-3-ol; 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester); 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester) (8CI); 1alphaH,5alphaH-Tropan-3alpha-ol; 1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester); 1alphaH,5alphaH-Tropan-3beta-ol; 2-Phenylhydracrylic acid 3-alpha-tropanyl ester; 8-Methyl-8-azabicyclo[321]oct-3-yl 3-hydroxy-2-phenylpropanoate; 8-Methyl-8-azabicyclo[321]oct-3-yl tropate; 8-Methyl-8-azabicyclo[321]octan-3-yl 3-hydroxy-2-phenylpropionate
Indication
Disease Entry ICD 11 Status REF
Organophosphate poisoning NE6Z Approved [1]
Poison intoxication NE6Z Phase 1 [1]
Therapeutic Class
Antiarrhythmic Agents
Cross-matching ID
PubChem CID
174174
ChEBI ID
CHEBI:16684
CAS Number
CAS 51-55-8
TTD Drug ID
DMEN6X7
VARIDT Drug ID
DR00665
ACDINA Drug ID
D00851

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Muscarinic acetylcholine receptor M5 (CHRM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Promazine DMZAL7W Acute intermittent hepatic porphyria 5C58.11 Approved [8]
ACECLIDINE DMOLNCZ Glaucoma/ocular hypertension 9C61 Approved [9]
Pilocarpine DMV9ADG Glaucoma/ocular hypertension 9C61 Approved [10]
Anisodine DMNOSWU Central and peripheral nervous disease 8A04-8E7Z Approved [11]
Propiverine DMUWBIJ Urinary incontinence MF50.2 Approved [12]
Umeclidinium DM4E8O9 Chronic obstructive pulmonary disease CA22 Approved [13]
Cimetropium bromide DMZHPNE Gastric motility disorder DA21 Approved [14]
Butylscopolamine DMZKXB7 Dysmenorrhea GA34.3 Approved [15]
Trospium DMX6RTG Overactive bladder GC50.0 Approved [16]
Choline alfoscerate DMOI1ZF Amnesia MB21.1 Approved [17]
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Drug(s) Transported By Organic cation transporter 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [19]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [20]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [21]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [23]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [24]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [25]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [26]
Propranolol DM79NTF Angina pectoris BA40 Approved [27]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [28]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [5]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [5]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [29]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [28]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [5]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [30]
Gefitinib DM15F0X Colon adenocarcinoma Approved [28]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [31]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [28]
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Drug(s) Affected By G1/S-specific cyclin-E2 (CCNE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [33]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [34]
Methotrexate DM2TEOL Anterior urethra cancer Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [37]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [38]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [39]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [41]
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Drug(s) Affected By Antileukoproteinase (SLPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [4]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [4]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [4]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [4]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [4]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [4]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [4]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [4]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Selenium DM25CGV N. A. N. A. Approved [45]
Etretinate DM2CZFA Keratosis ED56 Approved [46]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [36]
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Drug(s) Affected By Muscarinic acetylcholine receptor M4 (CHRM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ALCURONIUM DM2U4XQ Anaesthesia 9A78.6 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Acetylcholine DMDF79Z Cataract 9B10 Approved [52]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [53]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [54]
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [55]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [55]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [56]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [57]
brucine DM50RUD Discovery agent N.A. Investigative [50]
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Drug(s) Affected By Muscarinic acetylcholine receptor M1 (CHRM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pirenzepine DMP6M1N Peptic ulcer DA61 Approved [58]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [59]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [60]
Acetylcholine DMDF79Z Cataract 9B10 Approved [61]
Clozapine DMFC71L Schizophrenia 6A20 Approved [62]
Olanzapine DMPFN6Y Bipolar depression Approved [63]
Gallamine Triethiodide DMPO0MS Stabilize muscle contraction FB3Z Approved [64]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [61]
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [55]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [65]
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Drug(s) Affected By Neuronal acetylcholine receptor subunit beta-2 (CHRNB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [67]
Rivastigmine DMG629M Alzheimer disease 8A20 Approved [67]
Scopolamine DMOM8AL Addictive disorder 6C50-6C5Z Approved [67]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [68]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [69]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [70]
CYTISINE DMUF0BJ Tobacco dependence 6C4A.2 Phase 3 [71]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [56]
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Drug(s) Affected By Muscarinic acetylcholine receptor M3 (CHRM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylscopolamine DM5VWOB Peptic ulcer DA61 Approved [55]
Carbachol DMX9K8F Glaucoma/ocular hypertension 9C61 Approved [72]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Panobinostat DM58WKG Chronic graft versus host disease Approved [74]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [75]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Acetylcholine DMDF79Z Cataract 9B10 Approved [7]
Arsenic DMTL2Y1 N. A. N. A. Approved [77]
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Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [78]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [80]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [81]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Fluoxetine DM3PD2C Bipolar depression Approved [84]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
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Drug(s) Affected By DNA replication licensing factor MCM4 (MCM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [49]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
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Drug(s) Affected By Neuronal acetylcholine receptor subunit alpha-4 (CHRNA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [95]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [67]
Rivastigmine DMG629M Alzheimer disease 8A20 Approved [67]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [96]
Scopolamine DMOM8AL Addictive disorder 6C50-6C5Z Approved [67]
Arsenic DMTL2Y1 N. A. N. A. Approved [77]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [97]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [96]
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Drug(s) Affected By Cyclin-A1 (CCNA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [99]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [98]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [101]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [99]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Folic Acid DMEMBJC Colorectal carcinoma Approved [102]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [103]
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Drug(s) Affected By Cell division cycle protein 20 homolog (CDC20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Methotrexate DM2TEOL Anterior urethra cancer Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [105]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
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Drug(s) Affected By DNA replication licensing factor MCM6 (MCM6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [107]
Testosterone DM7HUNW Hot flushes GA30 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [108]
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Drug(s) Affected By NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [109]
Selenium DM25CGV N. A. N. A. Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [43]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [111]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [115]
Ethanol DMDRQZU Chronic pain MG30 Approved [116]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [117]
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Drug(s) Affected By Solute carrier family 22 member 3 (SLC22A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [118]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [118]
Norepinephrine DMOUC09 Alopecia ED70 Approved [118]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [108]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [122]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [123]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Muscarinic acetylcholine receptor M5 (CHRM5) TTH18TF ACM5_HUMAN Antagonist [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Antileukoproteinase (SLPI) OTUNFUU8 SLPI_HUMAN Gene/Protein Processing [4]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [5]
Cell division cycle protein 20 homolog (CDC20) OTCOEZRV CDC20_HUMAN Gene/Protein Processing [6]
Cyclin-A1 (CCNA1) OTX4HD45 CCNA1_HUMAN Gene/Protein Processing [6]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Gene/Protein Processing [6]
DNA replication licensing factor MCM4 (MCM4) OT19PNNG MCM4_HUMAN Gene/Protein Processing [6]
DNA replication licensing factor MCM6 (MCM6) OTKLIAWT MCM6_HUMAN Gene/Protein Processing [6]
G1/S-specific cyclin-E1 (CCNE1) OTLD7UID CCNE1_HUMAN Gene/Protein Processing [6]
G1/S-specific cyclin-E2 (CCNE2) OTBBUKQQ CCNE2_HUMAN Gene/Protein Processing [6]
Muscarinic acetylcholine receptor M1 (CHRM1) OTKW3E6B ACM1_HUMAN Gene/Protein Processing [7]

References

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2 Additive protective effects of donepezil and nicotine against salsolinol-induced cytotoxicity in SH-SY5Y cells. Neurotox Res. 2009 Oct;16(3):194-204.
3 Identification of novel substrates and structure-activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2. J Med Chem. 2013 Sep 26;56(18):7232-42.
4 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
5 Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). Toxicol Sci. 2013 Dec;136(2):328-43.
6 Gene expression signature of parathion-transformed human breast epithelial cells. Int J Mol Med. 2007 May;19(5):741-50.
7 Assessment of false transmitters as treatments for nerve agent poisoning. Toxicol Lett. 2020 Mar 15;321:21-31. doi: 10.1016/j.toxlet.2019.12.010. Epub 2019 Dec 9.
8 Muscarinic cholinergic and histamine H1 receptor binding of phenothiazine drug metabolites. Life Sci. 1988;43(5):405-12.
9 Design, synthesis, and neurochemical evaluation of 5-(3-alkyl-1,2,4- oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidines as M1 muscarinic receptor agonists. J Med Chem. 1993 Apr 2;36(7):842-7.
10 Retinoic acid prevents virus-induced airway hyperreactivity and M2 receptor dysfunction via anti-inflammatory and antiviral effects. Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L340-6.
11 Medicinal plants in therapy. Bull World Health Organ. 1985;63(6):965-81.
12 Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland. Life Sci. 1999;64(25):2351-8.
13 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7354).
14 Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
15 Comparison of pharmacological effects of L- and DL-n-butyl-scopolamine in rat uterus. Yao Xue Xue Bao. 1994;29(1):24-7.
16 Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.
17 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 467).
18 Are organic cation transporters capable of transporting prostaglandins? Naunyn Schmiedebergs Arch Pharmacol. 2005 Aug;372(2):125-30.
19 Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family). J Pharmacol Exp Ther. 2006 Nov;319(2):879-86.
20 Pharmacologic markers and predictors of responses to imatinib therapy in patients with chronic myeloid leukemia. Leuk Lymphoma. 2008 Apr;49(4):639-42.
21 Organic cation transporters are determinants of oxaliplatin cytotoxicity. Cancer Res. 2006 Sep 1;66(17):8847-57.
22 Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions. Pharm Res. 2013 Apr;30(4):996-1007.
23 Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett. 2006 Mar 8;234(1):4-33.
24 Upregulation of histone acetylation reverses organic anion transporter 2 repression and enhances 5-fluorouracil sensitivity in hepatocellular carcinoma
25 Comparison of type I and type II organic cation transport by organic cation transporters and organic anion-transporting polypeptides. J Pharmacol Exp Ther. 2001 Jul;298(1):110-5.
26 Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences. Drug Metab Pharmacokinet. 2008;23(4):243-53.
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