General Information of Drug (ID: DMZLGRB)

Drug Name
Pimecrolimus Drug Info
Synonyms Elidel; ASM 981; SDZ ASM 981; ASM-981; ASM-998; Elidel (TN); SDZ-ASM 981; Pimecrolimus [USAN:INN:BAN]; SDZ-ASM-981; Pimecrolimus (JAN/USAN/INN); 33-epi-Chloro-33-desoxyascomycin
Indication
Disease Entry ICD 11 Status REF
Atopic dermatitis EA80 Approved [1]
Therapeutic Class
Dermatologic Agents
Cross-matching ID
PubChem CID
6509979
ChEBI ID
CHEBI:135888
CAS Number
CAS 137071-32-0
TTD Drug ID
DMZLGRB
INTEDE Drug ID
DR1289

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Drug(s) Targeting Calcineurin (PPP3CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tacrolimus DMZ7XNQ Graft-versus-host disease 4B24 Approved [7]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [8]
Voclosporin DMWIJTN Lupus nephritis 4A40.0Y Approved [9]
L-685,818 DMJUQT1 Discovery agent N.A. Investigative [10]
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [12]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [13]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [15]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [16]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [17]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [18]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [12]
Verapamil DMA7PEW Angina pectoris BA40 Approved [19]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [20]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [22]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [23]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [24]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [24]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [25]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [26]
Capsaicin DMGMF6V Back pain ME84.Z Approved [27]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [28]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [29]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [30]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [30]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [31]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [29]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [30]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [32]
Gefitinib DM15F0X Colon adenocarcinoma Approved [29]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [4]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [33]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [33]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [34]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [35]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [36]
Etidronic acid DM1XHYJ Bone Paget disease Approved [33]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [33]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [33]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [37]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [38]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [40]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [41]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [42]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [43]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [44]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [45]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [46]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [47]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [48]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [49]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [50]
Fructose DM43AN2 Vomiting MD90 Approved [51]
Ketoprofen DMRKXPT Bursitis Approved [51]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [53]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [54]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [58]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [59]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [60]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [68]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [69]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [70]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [72]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
Folic Acid DMEMBJC Colorectal carcinoma Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [76]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [76]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [51]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [77]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [78]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [81]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [82]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [84]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
Menthol DMG2KW7 Back pain ME84.Z Approved [88]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [91]
⏷ Show the Full List of 9 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Calcineurin (PPP3CA) TTA4LDE PP2BA_HUMAN Inhibitor [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [4]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Gene/Protein Processing [5]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [5]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Gene/Protein Processing [6]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Gene/Protein Processing [6]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Gene/Protein Processing [6]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Protein Interaction/Cellular Processes [5]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Gene/Protein Processing [6]
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) OTDK74C0 TNR4_HUMAN Gene/Protein Processing [6]

References

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