General Information of Drug Combination (ID: DCRBHOT)

Drug Combination Name
Progesterone Aspirin
Indication
Disease Entry Status REF
Preeclampsia Phase 1 [1]
Component Drugs Progesterone   DMUY35B Aspirin   DM672AH
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Progesterone
Disease Entry ICD 11 Status REF
Amenorrhea GA20.0 Approved [2]
Hot flushes GA30 Approved [3]
Premature labour JB00 Approved [4]
Contraception QA21 Phase 3 [5]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1 [6]
Endometrial carcinoma N.A. Investigative [3]
Endometriosis GA10 Investigative [3]
Progesterone Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Progesterone receptor (PGR) TTUV8G9 PRGR_HUMAN Agonist [26]
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Progesterone Interacts with 2 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [27]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [28]
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Progesterone Interacts with 17 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [29]
Cytochrome P450 2A6 (CYP2A6) DEJVYAZ CP2A6_HUMAN Metabolism [30]
Cytochrome P450 1A1 (CYP1A1) DE6OQ3W CP1A1_HUMAN Metabolism [31]
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Metabolism [32]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Metabolism [33]
Cytochrome P450 4B1 (CYP4B1) DEMF740 CP4B1_HUMAN Metabolism [34]
Glutathione S-transferase alpha-1 (GSTA1) DE4ZHS1 GSTA1_HUMAN Metabolism [35]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Metabolism [36]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Metabolism [37]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Metabolism [38]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [38]
Cytochrome P450 1B1 (CYP1B1) DE9QHP6 CP1B1_HUMAN Metabolism [39]
Cholesterol 24-hydroxylase (CYP46A1) DEKP5HX CP46A_HUMAN Metabolism [40]
Steroid 21-hydroxylase (CYP21A2) DE0JMZ5 CP21A_HUMAN Metabolism [41]
Aldo-keto reductase 1C1 (AKR1C1) DE7P2FB AK1C1_HUMAN Metabolism [42]
Cytochrome P450 MEG (cyp106) DEZ1H4L CPXM_BACME Metabolism [43]
Cytochrome P450 21A2 (cyp21) DEBY951 A0A250VKS1_STROL Metabolism [44]
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⏷ Show the Full List of 17 DME(s)
Progesterone Interacts with 859 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Decreases Expression [45]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Increases Hydroxylation [46]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Decreases Activity [47]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [48]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Phosphorylation [49]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Phosphorylation [49]
Progonadoliberin-1 (GNRH1) OTH8A44K GON1_HUMAN Decreases Abundance [50]
Solute carrier family 22 member 1 (SLC22A1) OT7817I4 S22A1_HUMAN Decreases Activity [51]
Solute carrier family 22 member 3 (SLC22A3) OTQYGVXX S22A3_HUMAN Decreases Activity [51]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Activity [52]
Fatty-acid amide hydrolase 1 (FAAH) OT9DX3N1 FAAH1_HUMAN Increases Expression [53]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Decreases Expression [11]
Claudin-5 (CLDN5) OTUX60YO CLD5_HUMAN Increases Expression [11]
Nuclear factor 1 B-type (NFIB) OTX94PD0 NFIB_HUMAN Increases Expression [11]
Ectoderm-neural cortex protein 1 (ENC1) OTJEUB6U ENC1_HUMAN Decreases Expression [11]
PDZ domain-containing protein 2 (PDZD2) OTPPVRGY PDZD2_HUMAN Increases Expression [11]
RIMS-binding protein 2 (RIMBP2) OTUNSVUJ RIMB2_HUMAN Increases Expression [11]
Synaptojanin-2 (SYNJ2) OTLRHXP1 SYNJ2_HUMAN Decreases Expression [11]
Low-density lipoprotein receptor class A domain-containing protein 4 (LDLRAD4) OTQUX50Z LRAD4_HUMAN Increases Expression [11]
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (CYP27B1) OTTK98BH CP27B_HUMAN Decreases Expression [11]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Decreases Expression [11]
Gremlin-1 (GREM1) OTCK4IGV GREM1_HUMAN Decreases Expression [11]
Dual specificity protein phosphatase CDC14B (CDC14B) OTAESVOZ CC14B_HUMAN Increases Expression [11]
Transcription factor Maf (MAF) OT1GR3IZ MAF_HUMAN Increases Expression [11]
Mammaglobin-B (SCGB2A1) OT9L87U9 SG2A1_HUMAN Increases Expression [11]
CCN family member 5 (CCN5) OTADU8JJ CCN5_HUMAN Decreases Expression [11]
Integrin beta-like protein 1 (ITGBL1) OTJDHE17 ITGBL_HUMAN Increases Expression [11]
Secretoglobin family 1D member 1 (SCGB1D1) OTA20BF2 SG1D1_HUMAN Increases Expression [11]
Secretoglobin family 1D member 2 (SCGB1D2) OTSYWZAQ SG1D2_HUMAN Increases Expression [11]
Actin-associated protein FAM107A (FAM107A) OTBG61YZ F107A_HUMAN Increases Expression [11]
Keratin, type II cytoskeletal 6A (KRT6A) OT392M5T K2C6A_HUMAN Increases Expression [11]
Retinol-binding protein 4 (RBP4) OTL9RBH5 RET4_HUMAN Increases Expression [11]
Alpha-1-acid glycoprotein 1 (ORM1) OTZKSBRE A1AG1_HUMAN Decreases Expression [11]
Keratin, type II cytoskeletal 6B (KRT6B) OTBXJYHY K2C6B_HUMAN Increases Expression [11]
Apolipoprotein D (APOD) OTT77XW8 APOD_HUMAN Increases Expression [11]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Decreases Expression [11]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Increases Expression [11]
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Increases Expression [11]
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) OTREV92I CEAM5_HUMAN Decreases Expression [11]
Neuromedin-B (NMB) OT4NLN6H NMB_HUMAN Decreases Expression [11]
Serum amyloid A-2 protein (SAA2) OTYAVJWG SAA2_HUMAN Increases Expression [11]
Alpha-amylase 1B (AMY1A) OT6G4B8O AMY1B_HUMAN Increases Expression [11]
Chromogranin-A (CHGA) OTXYX5JH CMGA_HUMAN Decreases Expression [11]
Creatine kinase B-type (CKB) OTUCKOTT KCRB_HUMAN Increases Expression [11]
Glutathione peroxidase 2 (GPX2) OTXI2NTI GPX2_HUMAN Decreases Expression [11]
Regulator of chromosome condensation (RCC1) OT25AGMB RCC1_HUMAN Decreases Expression [11]
Stromelysin-3 (MMP11) OTRTXDBM MMP11_HUMAN Decreases Expression [11]
Protein S100-A2 (S100A2) OTTGHJ1H S10A2_HUMAN Increases Expression [11]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) OTB06ESI ACSL1_HUMAN Increases Expression [11]
Gap junction alpha-4 protein (GJA4) OTUPCT1V CXA4_HUMAN Decreases Expression [11]
Small proline-rich protein 2B (SPRR2B) OTQ9WPKY SPR2B_HUMAN Decreases Expression [11]
Transcription factor SOX-11 (SOX11) OT4LG7LA SOX11_HUMAN Decreases Expression [11]
Regulator of G-protein signaling 2 (RGS2) OT0FSRW7 RGS2_HUMAN Increases Expression [11]
Large ribosomal subunit protein uL15 (RPL27A) OTQQHPL0 RL27A_HUMAN Decreases Expression [11]
Transcription factor SOX-9 (SOX9) OTVDJFGN SOX9_HUMAN Decreases Expression [11]
Sulfate transporter (SLC26A2) OTJNHNTO S26A2_HUMAN Increases Expression [11]
cAMP-dependent protein kinase catalytic subunit PRKX (PRKX) OTDAC6Z0 PRKX_HUMAN Increases Expression [11]
Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6) OTK13JKC MP2K6_HUMAN Increases Expression [11]
Ephrin-B2 (EFNB2) OT0DCUOM EFNB2_HUMAN Decreases Expression [11]
MAP3K7 C-terminal-like protein (MAP3K7CL) OT9J7RLC M3KCL_HUMAN Decreases Expression [11]
Transmembrane protease serine 3 (TMPRSS3) OT0GTO1Z TMPS3_HUMAN Decreases Expression [11]
Small ribosomal subunit protein uS10 (RPS20) OTI8052R RS20_HUMAN Decreases Expression [11]
Heart- and neural crest derivatives-expressed protein 2 (HAND2) OTCXYW4Y HAND2_HUMAN Increases Expression [11]
Hemoglobin subunit alpha (HBA1) OTW2BQF4 HBA_HUMAN Increases Expression [11]
Iroquois-class homeodomain protein IRX-4 (IRX4) OT0TV6WK IRX4_HUMAN Increases Expression [11]
Sushi repeat-containing protein SRPX (SRPX) OT5B9LXS SRPX_HUMAN Increases Expression [11]
Fibulin-2 (FBLN2) OTEHR7N7 FBLN2_HUMAN Increases Expression [11]
Norrin (NDP) OTGDJ4US NDP_HUMAN Increases Expression [11]
Transcription factor SOX-4 (SOX4) OTSS40SS SOX4_HUMAN Decreases Expression [11]
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5) OT404F9K FKBP5_HUMAN Increases Expression [11]
SPARC-like protein 1 (SPARCL1) OT74DWMV SPRL1_HUMAN Increases Expression [11]
Latent-transforming growth factor beta-binding protein 1 (LTBP1) OTR7Q75L LTBP1_HUMAN Increases Expression [11]
Killer cell immunoglobulin-like receptor 2DS1 (KIR2DS1) OTRPOQGK KI2S1_HUMAN Increases Expression [11]
ATP-sensitive inward rectifier potassium channel 8 (KCNJ8) OTZ8G8FE KCNJ8_HUMAN Increases Expression [11]
Protein GREB1 (GREB1) OTU6ZA26 GREB1_HUMAN Increases Expression [11]
Glycine N-acyltransferase (GLYAT) OT3WWYXD GLYAT_HUMAN Increases Expression [11]
MTOR-associated protein MEAK7 (MEAK7) OT9A8JSO MEAK7_HUMAN Increases Expression [11]
ATPase family AAA domain-containing protein 2 (ATAD2) OT8MCRNY ATAD2_HUMAN Increases Expression [11]
PTB-containing, cubilin and LRP1-interacting protein (PID1) OT5YJ7FI PCLI1_HUMAN Increases Expression [11]
Adiponectin receptor protein 2 (ADIPOR2) OT2HDTL8 PAQR2_HUMAN Increases Expression [11]
Four-jointed box protein 1 (FJX1) OT8SVTSS FJX1_HUMAN Decreases Expression [11]
Neuroligin-4, X-linked (NLGN4X) OTDJGBK8 NLGNX_HUMAN Increases Expression [11]
Metallothionein-1M (MT1M) OTVT8PLU MT1M_HUMAN Increases Expression [11]
Protein cornichon homolog 3 (CNIH3) OTNLZ2QS CNIH3_HUMAN Decreases Expression [11]
Cholinephosphotransferase 1 (CHPT1) OT4FJ0K3 CHPT1_HUMAN Increases Expression [11]
Secreted and transmembrane protein 1 (SECTM1) OT5500CF SCTM1_HUMAN Increases Expression [11]
Transmembrane protein 158 (TMEM158) OT0KUBBI TM158_HUMAN Decreases Expression [11]
Tribbles homolog 2 (TRIB2) OTHSX3MX TRIB2_HUMAN Decreases Expression [11]
Type II iodothyronine deiodinase (DIO2) OTGPNSLH IOD2_HUMAN Decreases Expression [11]
TSC22 domain family protein 3 (TSC22D3) OT03UM03 T22D3_HUMAN Increases Expression [11]
Fermitin family homolog 1 (FERMT1) OT626PBA FERM1_HUMAN Decreases Expression [11]
Keratin, type I cytoskeletal 23 (KRT23) OTQW6UAG K1C23_HUMAN Decreases Expression [11]
Cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2) OTVSFHTL CRLD2_HUMAN Increases Expression [11]
Regulator of cell cycle RGCC (RGCC) OTYJMLWM RGCC_HUMAN Increases Expression [11]
Carbohydrate sulfotransferase 7 (CHST7) OT9HCUST CHST7_HUMAN Increases Expression [11]
Fas apoptotic inhibitory molecule 1 (FAIM) OTR67PGU FAIM1_HUMAN Increases Expression [11]
Dapper homolog 1 (DACT1) OT19Z704 DACT1_HUMAN Decreases Expression [11]
Pleckstrin-2 (PLEK2) OTUBWUUK PLEK2_HUMAN Decreases Expression [11]
LIM and cysteine-rich domains protein 1 (LMCD1) OT3AWE8O LMCD1_HUMAN Increases Expression [11]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) OTHCDQ22 PRGC1_HUMAN Increases Expression [11]
Lysophosphatidic acid receptor 3 (LPAR3) OTYOFT3K LPAR3_HUMAN Increases Expression [11]
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2) OTHTAM54 AAKG2_HUMAN Increases Expression [11]
Interleukin-20 receptor subunit alpha (IL20RA) OTSIVBVS I20RA_HUMAN Increases Expression [11]
Large neutral amino acids transporter small subunit 2 (SLC7A8) OT8XXVO8 LAT2_HUMAN Increases Expression [11]
Protein FAM153A (FAM153A) OTNHG4S2 F153A_HUMAN Decreases Expression [11]
Potassium voltage-gated channel subfamily G member 1 (KCNG1) OTZ9ZRG8 KCNG1_HUMAN Increases Expression [11]
Cdc42 effector protein 3 (CDC42EP3) OTUZ3U9Z BORG2_HUMAN Increases Expression [11]
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMTS8) OT2KFY1S ATS8_HUMAN Increases Expression [11]
Thrombospondin type-1 domain-containing protein 7A (THSD7A) OT7249HH THS7A_HUMAN Increases Expression [11]
Calpain-6 (CAPN6) OT8K5PR5 CAN6_HUMAN Increases Expression [11]
Unconventional myosin-XVI (MYO16) OTMS3D8W MYO16_HUMAN Increases Expression [11]
Alternative prion protein (PRNP) OTE85L1Q APRIO_HUMAN Increases Expression [12]
Interferon-related developmental regulator 1 (IFRD1) OT4SQMLQ IFRD1_HUMAN Increases Expression [12]
Myc box-dependent-interacting protein 1 (BIN1) OTK8O0X8 BIN1_HUMAN Increases Expression [12]
Nucleolar protein 56 (NOP56) OTT67SRZ NOP56_HUMAN Decreases Expression [12]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Increases Expression [12]
Integrin beta-1-binding protein 1 (ITGB1BP1) OTVQFNGS ITBP1_HUMAN Decreases Expression [12]
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF1) OTFK8KDP NHRF1_HUMAN Decreases Expression [12]
Tax1-binding protein 3 (TAX1BP3) OTQ6IB4T TX1B3_HUMAN Decreases Expression [12]
BET1 homolog (BET1) OTGX2557 BET1_HUMAN Increases Expression [12]
Period circadian protein homolog 1 (PER1) OTVQF3WX PER1_HUMAN Increases Expression [12]
ATP-dependent RNA helicase DHX15 (DHX15) OT4F98TK DHX15_HUMAN Decreases Expression [12]
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (ASAP2) OTGEXULW ASAP2_HUMAN Increases Expression [12]
Signal-induced proliferation-associated 1-like protein 1 (SIPA1L1) OTS6M0KO SI1L1_HUMAN Increases Expression [12]
U3 small nucleolar RNA-interacting protein 2 (RRP9) OT97EAV4 U3IP2_HUMAN Decreases Expression [12]
A-kinase anchor protein 8 (AKAP8) OTK3EQAI AKAP8_HUMAN Decreases Expression [12]
Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST1) OTABV7D2 H6ST1_HUMAN Decreases Expression [12]
Protein diaphanous homolog 1 (DIAPH1) OTZBYPLH DIAP1_HUMAN Decreases Expression [12]
Beta-1,4-galactosyltransferase 2 (B4GALT2) OTYIQT2F B4GT2_HUMAN Decreases Expression [12]
Slit homolog 1 protein (SLIT1) OT35RBNT SLIT1_HUMAN Decreases Expression [12]
Pre-mRNA-processing factor 40 homolog A (PRPF40A) OT6EXJZN PR40A_HUMAN Increases Expression [12]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Increases Expression [12]
Glutamine--fructose-6-phosphate aminotransferase 2 (GFPT2) OTYKP5G0 GFPT2_HUMAN Increases Expression [12]
Chondroitin sulfate proteoglycan 5 (CSPG5) OTXFEBWR CSPG5_HUMAN Decreases Expression [12]
Transforming acidic coiled-coil-containing protein 2 (TACC2) OTW4M7HI TACC2_HUMAN Increases Expression [12]
Tripartite motif-containing protein 16 (TRIM16) OTLRXYOZ TRI16_HUMAN Decreases Expression [12]
Phosphoacetylglucosamine mutase (PGM3) OTHS1ZSP AGM1_HUMAN Increases Expression [12]
BAG family molecular chaperone regulator 3 (BAG3) OTVXYUDQ BAG3_HUMAN Increases Expression [12]
Metallothionein-1E (MT1E) OTXJKU4Y MT1E_HUMAN Increases Expression [12]
Metallothionein-1B (MT1B) OTUA4FFH MT1B_HUMAN Increases Expression [12]
Fumarate hydratase, mitochondrial (FH) OTEQWU6Q FUMH_HUMAN Decreases Expression [12]
Tropomyosin alpha-1 chain (TPM1) OTD73X6R TPM1_HUMAN Decreases Expression [12]
Alpha-actinin-1 (ACTN1) OTUCLNXH ACTN1_HUMAN Decreases Expression [12]
Metallothionein-1G (MT1G) OTAV1OCR MT1G_HUMAN Increases Expression [12]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) OT1LQSGX MTDC_HUMAN Increases Expression [12]
Transcription factor JunD (JUND) OTNKACJD JUND_HUMAN Increases Expression [12]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Increases Expression [12]
Ephrin-A1 (EFNA1) OTU2NUA2 EFNA1_HUMAN Increases Expression [12]
Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1) OTGP6GA4 NR4A1_HUMAN Increases Expression [12]
Splicing factor, proline- and glutamine-rich (SFPQ) OTLCIAPJ SFPQ_HUMAN Decreases Expression [12]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [12]
Myosin regulatory light polypeptide 9 (MYL9) OT6B22JB MYL9_HUMAN Decreases Expression [12]
DnaJ homolog subfamily B member 1 (DNAJB1) OTCOSEVH DNJB1_HUMAN Increases Expression [12]
DNA repair nuclease/redox regulator APEX1 (APEX1) OT53OI14 APEX1_HUMAN Decreases Expression [12]
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF) OTRA8ZVE PPIF_HUMAN Decreases Expression [12]
Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1) OTAYZZE6 AL3A1_HUMAN Decreases Expression [12]
Homeobox protein Hox-A10 (HOXA10) OTB6GQ09 HXA10_HUMAN Decreases Expression [12]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [12]
ADP-ribosylation factor-like protein 4A (ARL4A) OTAH2GFA ARL4A_HUMAN Increases Expression [12]
DNA-binding protein inhibitor ID-1 (ID1) OTKGNZN5 ID1_HUMAN Increases Expression [12]
Glycine--tRNA ligase (GARS1) OT5B6R9Y GARS_HUMAN Increases Expression [12]
Serine--tRNA ligase, cytoplasmic (SARS1) OTFKXQ1O SYSC_HUMAN Increases Expression [12]
CCAAT/enhancer-binding protein delta (CEBPD) OTNBIPMY CEBPD_HUMAN Increases Expression [12]
CCAAT/enhancer-binding protein gamma (CEBPG) OTGNAX3H CEBPG_HUMAN Increases Expression [12]
Eukaryotic translation initiation factor 5 (EIF5) OT79PQUN IF5_HUMAN Increases Expression [12]
Apolipoprotein C-IV (APOC4) OTE8ZUXY APOC4_HUMAN Decreases Expression [12]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Decreases Expression [12]
Sestrin-2 (SESN2) OT889IXY SESN2_HUMAN Increases Expression [12]
LIM domain transcription factor LMO4 (LMO4) OT5NDCT9 LMO4_HUMAN Increases Expression [12]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Decreases Expression [12]
GTP-binding nuclear protein Ran (RAN) OT2TER5M RAN_HUMAN Decreases Expression [12]
Metallothionein-1H (MT1H) OT0MVBM6 MT1H_HUMAN Increases Expression [12]
Metallothionein-1X (MT1X) OT9AKFVS MT1X_HUMAN Increases Expression [12]
Small ribosomal subunit protein bS6m (MRPS6) OTKFY73U RT06_HUMAN Increases Expression [12]
CD83 antigen (CD83) OT1V4WQF CD83_HUMAN Decreases Expression [12]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Decreases Expression [12]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Increases Expression [12]
Sex-determining region Y protein (SRY) OT516T6D SRY_HUMAN Increases Expression [12]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) OTPYQX3K C1QBP_HUMAN Decreases Expression [12]
Hyaluronidase-2 (HYAL2) OTTVINXW HYAL2_HUMAN Decreases Expression [12]
Krueppel-like factor 10 (KLF10) OT4F4UGS KLF10_HUMAN Decreases Expression [12]
Serine/arginine-rich splicing factor 6 (SRSF6) OTGLOSYE SRSF6_HUMAN Decreases Expression [12]
Syntaxin-3 (STX3) OT4CIWLJ STX3_HUMAN Increases Expression [12]
Trophoblast glycoprotein (TPBG) OTU2OTLL TPBG_HUMAN Increases Expression [12]
Integrin alpha-7 (ITGA7) OTTBTAYW ITA7_HUMAN Increases Expression [12]
Krueppel-like factor 5 (KLF5) OT1ABI9N KLF5_HUMAN Increases Expression [12]
Coactosin-like protein (COTL1) OT6YCNLF COTL1_HUMAN Decreases Expression [12]
Tubulin--tyrosine ligase-like protein 12 (TTLL12) OTJQ8RF4 TTL12_HUMAN Decreases Expression [12]
Fibroblast growth factor-binding protein 1 (FGFBP1) OTP4BSCH FGFP1_HUMAN Decreases Expression [12]
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) OT9EROL6 HERP1_HUMAN Increases Expression [12]
Ribosome biogenesis regulatory protein homolog (RRS1) OTTNCZN6 RRS1_HUMAN Decreases Expression [12]
Plectin (PLEC) OTU4XDEG PLEC_HUMAN Decreases Expression [12]
Homeobox protein TGIF1 (TGIF1) OTN9VHAG TGIF1_HUMAN Increases Expression [12]
Dual specificity protein phosphatase 5 (DUSP5) OTH96RA7 DUS5_HUMAN Increases Expression [12]
Centrosomal protein kizuna (KIZ) OT5VCKSM KIZ_HUMAN Increases Expression [12]
Pleckstrin homology-like domain family A member 2 (PHLDA2) OTMV9DPP PHLA2_HUMAN Increases Expression [12]
Immediate early response gene 5-like protein (IER5L) OT6IG629 IER5L_HUMAN Increases Expression [12]
Rho-related GTP-binding protein RhoU (RHOU) OTERIAD4 RHOU_HUMAN Increases Expression [12]
TBC1 domain family member 1 (TBC1D1) OTI9V7B0 TBCD1_HUMAN Increases Expression [12]
E3 ubiquitin-protein ligase synoviolin (SYVN1) OTZ4ZJP5 SYVN1_HUMAN Increases Expression [12]
F-box only protein 11 (FBXO11) OTGWF3Q2 FBX11_HUMAN Increases Expression [12]
Prostaglandin reductase 2 (PTGR2) OTYPYOUM PTGR2_HUMAN Increases Expression [12]
Solute carrier family 4 member 11 (SLC4A11) OTMMNQ2E S4A11_HUMAN Decreases Expression [12]
sn-1-specific diacylglycerol lipase ABHD11 (ABHD11) OTJE9UZY ABHDB_HUMAN Decreases Expression [12]
Ribosome biogenesis protein BRX1 homolog (BRIX1) OTQ5F1D1 BRX1_HUMAN Decreases Expression [12]
RB1-inducible coiled-coil protein 1 (RB1CC1) OTZK8PFX RBCC1_HUMAN Increases Expression [12]
Importin-4 (IPO4) OT2N5020 IPO4_HUMAN Decreases Expression [12]
Gem-associated protein 6 (GEMIN6) OTE262KF GEMI6_HUMAN Decreases Expression [12]
Paraspeckle component 1 (PSPC1) OTYS6WQ8 PSPC1_HUMAN Decreases Expression [12]
Nanos homolog 1 (NANOS1) OT3UNZZY NANO1_HUMAN Decreases Expression [12]
Jun dimerization protein 2 (JDP2) OTW35WKX JDP2_HUMAN Increases Expression [12]
SEC14-like protein 1 (SEC14L1) OTA75FET S14L1_HUMAN Increases Expression [12]
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (PPP2R3C) OT7E6V9B P2R3C_HUMAN Decreases Expression [12]
Nucleoporin SEH1 (SEH1L) OTHW13AE SEH1_HUMAN Decreases Expression [12]
tRNA-dihydrouridine(47) synthase -like (DUS3L) OTNY343A DUS3L_HUMAN Decreases Expression [12]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) OT8C6PKL AGAP3_HUMAN Decreases Expression [12]
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) OTALABSK S38A2_HUMAN Increases Expression [12]
Erbin (ERBIN) OTNWTUA8 ERBIN_HUMAN Increases Expression [12]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Increases Expression [12]
Noelin (OLFM1) OTOYPEWW NOE1_HUMAN Decreases Expression [12]
BAG family molecular chaperone regulator 1 (BAG1) OTRQNIA4 BAG1_HUMAN Decreases Expression [12]
Retinoic acid receptor responder protein 2 (RARRES2) OT1BJE8K RARR2_HUMAN Decreases Expression [12]
Glutamate-rich WD repeat-containing protein 1 (GRWD1) OT6M13ZV GRWD1_HUMAN Decreases Expression [12]
Transmembrane protein 47 (TMEM47) OTAJ4CPX TMM47_HUMAN Increases Expression [12]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Increases Expression [12]
Very long chain fatty acid elongase 1 (ELOVL1) OTIDTQ8R ELOV1_HUMAN Decreases Expression [12]
TBC1 domain family member 2A (TBC1D2) OTSGHPD0 TBD2A_HUMAN Decreases Expression [12]
Zinc finger protein GLIS2 (GLIS2) OTOUUV1X GLIS2_HUMAN Decreases Expression [12]
Protein sprouty homolog 4 (SPRY4) OT2VK9N0 SPY4_HUMAN Increases Expression [12]
Protein rogdi homolog (ROGDI) OTZ7LSKJ ROGDI_HUMAN Decreases Expression [12]
Cysteine/serine-rich nuclear protein 2 (CSRNP2) OTRZNC1C CSRN2_HUMAN Increases Expression [12]
Opsin-3 (OPN3) OTON6BFU OPN3_HUMAN Increases Expression [12]
Phosducin-like protein 3 (PDCL3) OTD3WGV1 PDCL3_HUMAN Decreases Expression [12]
GDP-fucose protein O-fucosyltransferase 1 (POFUT1) OTOBJZIT OFUT1_HUMAN Decreases Expression [12]
EH domain-containing protein 1 (EHD1) OTDMEKLV EHD1_HUMAN Decreases Expression [12]
DNA-directed RNA polymerase I subunit RPA2 (POLR1B) OTKREU8M RPA2_HUMAN Decreases Expression [12]
GrpE protein homolog 1, mitochondrial (GRPEL1) OT8O00YJ GRPE1_HUMAN Decreases Expression [12]
POZ-, AT hook-, and zinc finger-containing protein 1 (PATZ1) OT0X9WGR PATZ1_HUMAN Decreases Expression [12]
MAP kinase-interacting serine/threonine-protein kinase 2 (MKNK2) OTNA9G8V MKNK2_HUMAN Increases Expression [12]
Stromal cell-derived factor 2-like protein 1 (SDF2L1) OTE7JIO2 SDF2L_HUMAN Increases Expression [12]
Fructose-2,6-bisphosphatase TIGAR (TIGAR) OTR7NMRJ TIGAR_HUMAN Decreases Expression [12]
DNA polymerase epsilon subunit 4 (POLE4) OTCMWUT6 DPOE4_HUMAN Decreases Expression [12]
Dual specificity protein phosphatase 22 (DUSP22) OTEZ3U85 DUS22_HUMAN Increases Expression [12]
p21-activated protein kinase-interacting protein 1 (PAK1IP1) OT21CROX PK1IP_HUMAN Decreases Expression [12]
DNA damage-inducible transcript 4 protein (DDIT4) OTHY8SY4 DDIT4_HUMAN Increases Expression [12]
H/ACA ribonucleoprotein complex subunit 1 (GAR1) OTA580RX GAR1_HUMAN Decreases Expression [12]
Protocadherin Fat 2 (FAT2) OTRGT3E8 FAT2_HUMAN Decreases Expression [12]
Myoferlin (MYOF) OTRFC3IJ MYOF_HUMAN Decreases Expression [12]
]-phosphatase 1, mitochondrial (PDP1) OT82RTMT PDP1_HUMAN Decreases Expression [12]
Large ribosomal subunit protein bL27m (MRPL27) OT27BQQ6 RM27_HUMAN Decreases Expression [12]
SH3 domain-binding protein 4 (SH3BP4) OTVIRKW7 SH3B4_HUMAN Decreases Expression [12]
DnaJ homolog subfamily B member 9 (DNAJB9) OT38EQT6 DNJB9_HUMAN Increases Expression [12]
LIM domain and actin-binding protein 1 (LIMA1) OTONPC9R LIMA1_HUMAN Decreases Expression [12]
Cysteine and histidine-rich domain-containing protein 1 (CHORDC1) OT3W6F1U CHRD1_HUMAN Increases Expression [12]
General transcription factor II-I repeat domain-containing protein 1 (GTF2IRD1) OTEG9KU1 GT2D1_HUMAN Increases Expression [12]
mRNA turnover protein 4 homolog (MRTO4) OTZ4C6FH MRT4_HUMAN Decreases Expression [12]
Fibronectin type-III domain-containing protein 3A (FNDC3A) OTUX3S2I FND3A_HUMAN Increases Expression [12]
Small ribosomal subunit protein bS1m (MRPS28) OT8CLJ6M RT28_HUMAN Decreases Expression [12]
DNA-directed RNA polymerase III subunit RPC10 (POLR3K) OTZCSF6A RPC10_HUMAN Decreases Expression [12]
Hypoxia up-regulated protein 1 (HYOU1) OTBGBSOV HYOU1_HUMAN Increases Expression [12]
KAT8 regulatory NSL complex subunit 1-like protein (KANSL1L) OTOAH2RR KAL1L_HUMAN Increases Expression [13]
PDZ and LIM domain protein 1 (PDLIM1) OT4EGCPG PDLI1_HUMAN Decreases Expression [13]
Galectin-8 (LGALS8) OT71LJ8T LEG8_HUMAN Increases Expression [13]
Stearoyl-CoA desaturase (SCD) OTB1073G SCD_HUMAN Increases Expression [13]
Homeobox protein cut-like 2 (CUX2) OTDJTQAJ CUX2_HUMAN Decreases Expression [13]
Potassium channel subfamily K member 3 (KCNK3) OTWMAV6G KCNK3_HUMAN Decreases Expression [13]
Kinetochore protein NDC80 homolog (NDC80) OTS7D306 NDC80_HUMAN Increases Expression [13]
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) OT1Z1ZXE OGT1_HUMAN Decreases Expression [13]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Increases Expression [13]
Cytochrome b5 type B (CYB5B) OTONNAV1 CYB5B_HUMAN Increases Expression [13]
Origin recognition complex subunit 4 (ORC4) OT3ACTST ORC4_HUMAN Increases Expression [13]
HMG box-containing protein 1 (HBP1) OTDPGGDV HBP1_HUMAN Increases Expression [13]
Acyl-CoA (FADS1) OTUYOYHX FADS1_HUMAN Increases Expression [13]
Periplakin (PPL) OTTM4WDO PEPL_HUMAN Increases Expression [13]
Lathosterol oxidase (SC5D) OT41KMW4 SC5D_HUMAN Increases Expression [13]
Isocitrate dehydrogenase cytoplasmic (IDH1) OT4DLHC8 IDHC_HUMAN Increases Expression [13]
monooxygenase MICAL2 (MICAL2) OT04OQQJ MICA2_HUMAN Decreases Expression [13]
ATP-binding cassette sub-family C member 6 (ABCC6) OTZT0LKT MRP6_HUMAN Decreases Expression [13]
Cystatin-A (CSTA) OT1K68KE CYTA_HUMAN Decreases Expression [13]
Pro-neuropeptide Y (NPY) OT4ICV3P NPY_HUMAN Increases Expression [13]
Hemoglobin subunit delta (HBD) OTRQG4WA HBD_HUMAN Increases Expression [13]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Decreases Expression [13]
Collagen alpha-1(IV) chain (COL4A1) OTL6D1YE CO4A1_HUMAN Decreases Expression [13]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Decreases Expression [13]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Decreases Expression [13]
Matrix Gla protein (MGP) OTZWU3FU MGP_HUMAN Decreases Expression [13]
Neurofilament heavy polypeptide (NEFH) OTMSCW5I NFH_HUMAN Decreases Expression [13]
Collagen alpha-1(XI) chain (COL11A1) OTB0DRMS COBA1_HUMAN Decreases Expression [13]
Collagen alpha-1(VI) chain (COL6A1) OTYKSCOB CO6A1_HUMAN Decreases Expression [13]
Parathyroid hormone-related protein (PTHLH) OTI1JF13 PTHR_HUMAN Increases Expression [13]
Myosin-1 (MYH1) OT8YBDOT MYH1_HUMAN Decreases Expression [13]
Farnesyl pyrophosphate synthase (FDPS) OT6CKWV5 FPPS_HUMAN Increases Expression [13]
Immunoglobulin lambda-like polypeptide 1 (IGLL1) OTRTNVOG IGLL1_HUMAN Decreases Expression [13]
Desmin (DES) OTI09KBW DESM_HUMAN Decreases Expression [13]
Protein EVI2A (EVI2A) OTR8RUXQ EVI2A_HUMAN Increases Expression [13]
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) OTMWFDAC AT2B4_HUMAN Decreases Expression [13]
Cytochrome c oxidase subunit 7A1, mitochondrial (COX7A1) OTHV25GG CX7A1_HUMAN Decreases Expression [13]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Decreases Expression [13]
Collagen alpha-2(VIII) chain (COL8A2) OTASWJ69 CO8A2_HUMAN Decreases Expression [13]
Glycerol kinase (GK) OTK2YRA0 GLPK_HUMAN Increases Expression [13]
Serine hydroxymethyltransferase, cytosolic (SHMT1) OTIINA3J GLYC_HUMAN Increases Expression [13]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8) OTOZTA1F M3K8_HUMAN Increases Expression [13]
Cyclin-dependent kinase 4 inhibitor C (CDKN2C) OTCLOV90 CDN2C_HUMAN Increases Expression [13]
C-X-C motif chemokine 5 (CXCL5) OTZOUPCA CXCL5_HUMAN Increases Expression [13]
Protein PRRC2A (PRRC2A) OTBX6FM5 PRC2A_HUMAN Decreases Expression [13]
Centromere protein F (CENPF) OT7AG0SW CENPF_HUMAN Increases Expression [13]
Steroidogenic acute regulatory protein, mitochondrial (STAR) OTFEZ5AI STAR_HUMAN Decreases Expression [13]
ETS translocation variant 1 (ETV1) OT6PMJIK ETV1_HUMAN Increases Expression [13]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Decreases Expression [13]
Rho GDP-dissociation inhibitor 1 (ARHGDIA) OTEXWJDO GDIR1_HUMAN Decreases Expression [13]
A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAMTS20) OTU0EKLN ATS20_HUMAN Increases Expression [13]
N-acetylgalactosamine kinase (GALK2) OTHR35JF GALK2_HUMAN Increases Expression [13]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Increases Expression [13]
Dystonin (DST) OTHZBM4X DYST_HUMAN Decreases Expression [13]
Neurogenic locus notch homolog protein 2 (NOTCH2) OTQ3Y9PA NOTC2_HUMAN Decreases Expression [13]
Acetylcholine receptor subunit epsilon (CHRNE) OTGGXGGB ACHE_HUMAN Decreases Expression [13]
3-ketodihydrosphingosine reductase (KDSR) OTCIES3H KDSR_HUMAN Increases Expression [13]
Collagen alpha-1(XVI) chain (COL16A1) OTOWKUO2 COGA1_HUMAN Decreases Expression [13]
Nuclear pore complex protein Nup160 (NUP160) OTUKVV3I NU160_HUMAN Increases Expression [13]
Transformer-2 protein homolog alpha (TRA2A) OT5NHOO3 TRA2A_HUMAN Decreases Expression [13]
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) OTGM06VJ IDI1_HUMAN Increases Expression [13]
Ensconsin (MAP7) OTVSSJ33 MAP7_HUMAN Increases Expression [13]
Phosphatidate phosphatase LPIN1 (LPIN1) OTQ75KF2 LPIN1_HUMAN Increases Expression [13]
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) OTSMGKXQ EBP_HUMAN Increases Expression [13]
High mobility group nucleosome-binding domain-containing protein 3 (HMGN3) OTA2TBWS HMGN3_HUMAN Increases Expression [13]
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) OTK3EJFD NSDHL_HUMAN Increases Expression [13]
Protein NKG7 (NKG7) OTXDD006 NKG7_HUMAN Increases Expression [13]
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) OT34P56Z PDS5A_HUMAN Increases Expression [13]
TBC1 domain family member 25 (TBC1D25) OT11OABF TBC25_HUMAN Increases Expression [13]
Sterile alpha motif domain-containing protein 9 (SAMD9) OTDG48P0 SAMD9_HUMAN Increases Expression [13]
Centrosomal protein of 162 kDa (CEP162) OT39FSH8 CE162_HUMAN Increases Expression [13]
Telomere-associated protein RIF1 (RIF1) OTPE49OE RIF1_HUMAN Increases Expression [13]
La-related protein 4 (LARP4) OTB10IJH LARP4_HUMAN Increases Expression [13]
Centromere protein Q (CENPQ) OT3M6WAI CENPQ_HUMAN Increases Expression [13]
Protein MON2 homolog (MON2) OTCSVMAR MON2_HUMAN Increases Expression [13]
Adhesion G-protein coupled receptor G6 (ADGRG6) OTY2UBXO AGRG6_HUMAN Increases Expression [13]
Intraflagellar transport protein 70A (IFT70A) OTX4FKPQ IT70A_HUMAN Increases Expression [13]
Centrosomal protein of 57 kDa (CEP57) OTPOHLIX CEP57_HUMAN Increases Expression [13]
Bardet-Biedl syndrome 7 protein (BBS7) OTELYWDQ BBS7_HUMAN Increases Expression [13]
Abnormal spindle-like microcephaly-associated protein (ASPM) OTKXQMNA ASPM_HUMAN Increases Expression [13]
Lysosomal enzyme trafficking factor (LYSET) OT8XE247 LYSET_HUMAN Increases Expression [13]
Estradiol 17-beta-dehydrogenase 11 (HSD17B11) OT3VIM3B DHB11_HUMAN Increases Expression [13]
Holliday junction recognition protein (HJURP) OTWMV16B HJURP_HUMAN Increases Expression [13]
Putative tyrosine carboxypeptidase MATCAP2 (MATCAP2) OTZUC9LR MACA2_HUMAN Increases Expression [13]
Bardet-Biedl syndrome 10 protein (BBS10) OTL1TTWX BBS10_HUMAN Increases Expression [13]
Centrosomal protein of 76 kDa (CEP76) OTL2SJX0 CEP76_HUMAN Increases Expression [13]
Nuclear protein MDM1 (MDM1) OTI9JUWA MDM1_HUMAN Increases Expression [13]
Cyclic GMP-AMP phosphodiesterase SMPDL3A (SMPDL3A) OTQDYH8E ASM3A_HUMAN Increases Expression [13]
Homeobox protein DLX-4 (DLX4) OTLWVCN4 DLX4_HUMAN Increases Expression [13]
Serine/threonine-protein kinase Sgk3 (SGK3) OTQ6QO99 SGK3_HUMAN Increases Expression [13]
Autophagy-related protein 2 homolog B (ATG2B) OT7FGFJ1 ATG2B_HUMAN Increases Expression [13]
Centromere protein N (CENPN) OTRO7XPD CENPN_HUMAN Increases Expression [13]
Fatty acid hydroxylase domain-containing protein 2 (FAXDC2) OTRRS828 FXDC2_HUMAN Increases Expression [13]
Intraflagellar transport protein 74 homolog (IFT74) OTZBFEDD IFT74_HUMAN Increases Expression [13]
Krueppel-like factor 6 (KLF6) OTQY9S7F KLF6_HUMAN Increases Expression [13]
Cell division control protein 6 homolog (CDC6) OTX93FE7 CDC6_HUMAN Increases Expression [13]
A-kinase anchor protein 9 (AKAP9) OT7Z2YRP AKAP9_HUMAN Decreases Expression [13]
Spondin-2 (SPON2) OTE7JLNM SPON2_HUMAN Decreases Expression [13]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Increases Expression [13]
PR domain zinc finger protein 12 (PRDM12) OTOAUVAM PRD12_HUMAN Increases Expression [13]
GS homeobox 1 (GSX1) OTDZ5J1U GSX1_HUMAN Increases Expression [13]
Very long chain fatty acid elongase 6 (ELOVL6) OTB26UJJ ELOV6_HUMAN Increases Expression [13]
Cation channel sperm-associated auxiliary subunit beta (CATSPERB) OTZ0WQL2 CTSRB_HUMAN Decreases Expression [13]
Thiol S-methyltransferase TMT1A (TMT1A) OT4IAAZP TMT1A_HUMAN Increases Expression [13]
Synaptopodin 2-like protein (SYNPO2L) OTA7RKXZ SYP2L_HUMAN Increases Expression [13]
NADPH oxidase 3 (NOX3) OT0FFJH8 NOX3_HUMAN Decreases Expression [13]
Mucin-5B (MUC5B) OTPW6K5C MUC5B_HUMAN Increases Expression [13]
Inward rectifier potassium channel 16 (KCNJ16) OT174UPV KCJ16_HUMAN Increases Expression [13]
PDZ and LIM domain protein 7 (PDLIM7) OTAZVODU PDLI7_HUMAN Decreases Expression [13]
Inactive ubiquitin thioesterase OTULINL (OTULINL) OTNOC9L1 OTULL_HUMAN Increases Expression [13]
Fanconi anemia group I protein (FANCI) OTW8E3SC FANCI_HUMAN Increases Expression [13]
Protein kintoun (DNAAF2) OTB8YEJ5 KTU_HUMAN Increases Expression [13]
TBCC domain-containing protein 1 (TBCCD1) OT8WZ1LN TBCC1_HUMAN Increases Expression [13]
CDKN2A-interacting protein (CDKN2AIP) OT80RRQJ CARF_HUMAN Increases Expression [13]
Neurotrimin (NTM) OTHF0UQU NTRI_HUMAN Decreases Expression [13]
FERM domain-containing protein 4A (FRMD4A) OTJDTIK2 FRM4A_HUMAN Decreases Expression [13]
7-dehydrocholesterol reductase (DHCR7) OTLILBUI DHCR7_HUMAN Increases Expression [13]
Transcription termination factor 2 (TTF2) OT5LJOWM TTF2_HUMAN Increases Expression [13]
HBS1-like protein (HBS1L) OTA3U1N6 HBS1L_HUMAN Increases Expression [13]
Metal-response element-binding transcription factor 2 (MTF2) OTNL1O2O MTF2_HUMAN Increases Expression [13]
Protocadherin gamma-A3 (PCDHGA3) OTTOGYJA PCDG3_HUMAN Decreases Expression [13]
Protocadherin gamma-A11 (PCDHGA11) OTK9136T PCDGB_HUMAN Decreases Expression [13]
Protocadherin gamma-A1 (PCDHGA1) OTR1U1LI PCDG1_HUMAN Decreases Expression [13]
Chloride intracellular channel protein 4 (CLIC4) OT6KTPKD CLIC4_HUMAN Decreases Expression [13]
Tolloid-like protein 2 (TLL2) OTHZ4TBL TLL2_HUMAN Increases Expression [13]
CTD small phosphatase-like protein (CTDSPL) OTZJ0CZK CTDSL_HUMAN Increases Expression [14]
Keratin, type II cytoskeletal 7 (KRT7) OTLT3JFN K2C7_HUMAN Increases Expression [14]
Transcriptional activator Myb (MYB) OTJH64IV MYB_HUMAN Decreases Expression [14]
Glycophorin-E (GYPE) OTBHAG6A GLPE_HUMAN Increases Expression [14]
Solute carrier family 25 member 16 (SLC25A16) OTTTUL91 GDC_HUMAN Increases Expression [14]
Protein S100-P (S100P) OTJCXNJG S100P_HUMAN Increases Expression [14]
cGMP-gated cation channel alpha-1 (CNGA1) OT0RXMJN CNGA1_HUMAN Increases Expression [14]
M-phase inducer phosphatase 2 (CDC25B) OT12MSRY MPIP2_HUMAN Increases Expression [14]
Chitinase-3-like protein 1 (CHI3L1) OT2Z7VJH CH3L1_HUMAN Increases Expression [14]
ETS-related transcription factor Elf-3 (ELF3) OTUTLEQO ELF3_HUMAN Increases Expression [14]
Origin recognition complex subunit 2 (ORC2) OTLIYP8M ORC2_HUMAN Increases Expression [14]
Angio-associated migratory cell protein (AAMP) OTZXBSS4 AAMP_HUMAN Increases Expression [14]
CD166 antigen (ALCAM) OTCO4LP7 CD166_HUMAN Increases Expression [14]
FXYD domain-containing ion transport regulator 3 (FXYD3) OT9PPRHE FXYD3_HUMAN Increases Expression [14]
Nuclear mitotic apparatus protein 1 (NUMA1) OTTKAVG4 NUMA1_HUMAN Increases Expression [14]
Programmed cell death protein 4 (PDCD4) OTZ6NXUX PDCD4_HUMAN Increases Expression [14]
Quinone oxidoreductase PIG3 (TP53I3) OTSCM68G QORX_HUMAN Increases Expression [14]
Disks large homolog 5 (DLG5) OTU9Z17K DLG5_HUMAN Increases Expression [14]
E3 ubiquitin-protein ligase RNF5 (RNF5) OTDQGI37 RNF5_HUMAN Increases Expression [14]
Decapping and exoribonuclease protein (DXO) OTFDTNW4 DXO_HUMAN Increases Expression [15]
Natriuretic peptides A (NPPA) OTMQNTNX ANF_HUMAN Increases Expression [15]
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) OTPWI88U CEAM1_HUMAN Increases Expression [15]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Decreases Expression [15]
Aquaporin-2 (AQP2) OTQLBKK6 AQP2_HUMAN Increases Expression [15]
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) OTTM6KRB ADA17_HUMAN Decreases Expression [15]
Amino acid transporter heavy chain SLC3A1 (SLC3A1) OT56V01A SLC31_HUMAN Increases Expression [15]
Matrix metalloproteinase-26 (MMP26) OT9O89KU MMP26_HUMAN Decreases Expression [15]
Phospholipid phosphatase 3 (PLPP3) OTSSF7BK PLPP3_HUMAN Increases Expression [16]
Actin-binding LIM protein 1 (ABLIM1) OTHXEK3E ABLM1_HUMAN Increases Expression [16]
Inositol monophosphatase 2 (IMPA2) OTNFB9YN IMPA2_HUMAN Increases Expression [16]
Interferon regulatory factor 6 (IRF6) OTKJ44EV IRF6_HUMAN Increases Expression [16]
Inositol polyphosphate 4-phosphatase type II (INPP4B) OTLROA7G INP4B_HUMAN Decreases Expression [16]
Monocarboxylate transporter 7 (SLC16A6) OT7BIIZX MOT7_HUMAN Decreases Expression [16]
Phospholipid-transporting ATPase IC (ATP8B1) OTALGS63 AT8B1_HUMAN Decreases Expression [16]
Unconventional myosin-Ib (MYO1B) OTGZUJ0I MYO1B_HUMAN Decreases Expression [16]
Plexin-C1 (PLXNC1) OTJ5XKYY PLXC1_HUMAN Increases Expression [16]
Tyrosine-protein kinase JAK2 (JAK2) OTBIDOOR JAK2_HUMAN Increases Expression [16]
ATP-binding cassette sub-family C member 9 (ABCC9) OTGAXLQN ABCC9_HUMAN Increases Expression [16]
Protein diaphanous homolog 2 (DIAPH2) OTBEYFEZ DIAP2_HUMAN Increases Expression [16]
Microphthalmia-associated transcription factor (MITF) OT6XJCZH MITF_HUMAN Increases Expression [16]
Integrin alpha-10 (ITGA10) OTM0V5AO ITA10_HUMAN Increases Expression [16]
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS2) OTTK22NO ATS2_HUMAN Increases Expression [16]
All-trans-retinol dehydrogenase ADH1B (ADH1B) OTV3TB81 ADH1B_HUMAN Increases Expression [16]
Alcohol dehydrogenase 1C (ADH1C) OTO1DV7F ADH1G_HUMAN Increases Expression [16]
Neurofilament medium polypeptide (NEFM) OT8VCBNF NFM_HUMAN Decreases Expression [16]
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) OTXOQDSG IFIT1_HUMAN Decreases Expression [16]
Plastin-2 (LCP1) OTK61F2A PLSL_HUMAN Increases Expression [16]
Atrial natriuretic peptide receptor 3 (NPR3) OT6MQP3A ANPRC_HUMAN Increases Expression [16]
Alpha-2C adrenergic receptor (ADRA2C) OT5B9RKP ADA2C_HUMAN Increases Expression [16]
Ras-related protein Rab-3B (RAB3B) OTZA4SXL RAB3B_HUMAN Decreases Expression [16]
5'-nucleotidase (NT5E) OT7J5LT6 5NTD_HUMAN Decreases Expression [16]
Glutathione peroxidase 3 (GPX3) OT6PK94R GPX3_HUMAN Increases Expression [16]
Leiomodin-1 (LMOD1) OTZ2MEMG LMOD1_HUMAN Increases Expression [16]
Syndecan-4 (SDC4) OTKUVUGZ SDC4_HUMAN Decreases Expression [16]
ETS translocation variant 5 (ETV5) OTE2OBM4 ETV5_HUMAN Decreases Expression [16]
DNA-binding protein inhibitor ID-4 (ID4) OTPMJ39I ID4_HUMAN Increases Expression [16]
Epithelial membrane protein 2 (EMP2) OTPS2H0L EMP2_HUMAN Increases Expression [16]
ADP-ribosylation factor-like protein 4C (ARL4C) OTQ3QNNU ARL4C_HUMAN Decreases Expression [16]
Poly(rC)-binding protein 3 (PCBP3) OT6EX9N6 PCBP3_HUMAN Increases Expression [16]
Anthrax toxin receptor 2 (ANTXR2) OTOGFGOJ ANTR2_HUMAN Increases Expression [16]
Actin, gamma-enteric smooth muscle (ACTG2) OTRDWUO0 ACTH_HUMAN Increases Expression [16]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) OTF6OC66 GCNT1_HUMAN Increases Expression [16]
Complement factor H-related protein 1 (CFHR1) OT72R16T FHR1_HUMAN Increases Expression [16]
A-kinase anchor protein 13 (AKAP13) OTOZAR14 AKP13_HUMAN Increases Expression [16]
Monocyte to macrophage differentiation factor (MMD) OTB5I4OC PAQRB_HUMAN Increases Expression [16]
CD226 antigen (CD226) OT4UG0KB CD226_HUMAN Increases Expression [16]
Nuclear factor interleukin-3-regulated protein (NFIL3) OTQH9HM3 NFIL3_HUMAN Increases Expression [16]
Dual specificity protein phosphatase 6 (DUSP6) OT4H6RKW DUS6_HUMAN Decreases Expression [16]
FH1/FH2 domain-containing protein 3 (FHOD3) OT1WUBQX FHOD3_HUMAN Decreases Expression [16]
Galectin-related protein (LGALSL) OTC983KJ LEGL_HUMAN Decreases Expression [16]
PWWP domain-containing DNA repair factor 3B (PWWP3B) OTOV6EM9 PWP3B_HUMAN Increases Expression [16]
Sickle tail protein homolog (KIAA1217) OTRMK3PU SKT_HUMAN Increases Expression [16]
Protein furry homolog (FRY) OT74IAG2 FRY_HUMAN Decreases Expression [16]
Olfactomedin-like protein 2B (OLFML2B) OTDNJFR4 OLM2B_HUMAN Increases Expression [16]
Coiled-coil domain-containing protein 102B (CCDC102B) OTVDZVD0 C102B_HUMAN Increases Expression [16]
Protein Jade-1 (JADE1) OTBPJIRI JADE1_HUMAN Increases Expression [16]
Protein TMED8 (TMED8) OTPVXP0K TMED8_HUMAN Increases Expression [16]
Ras-like protein family member 11A (RASL11A) OTDO6CMY RSLBA_HUMAN Increases Expression [16]
Ceramide synthase 6 (CERS6) OTOP4GV1 CERS6_HUMAN Increases Expression [16]
Patched domain-containing protein 4 (PTCHD4) OTGJ8NRP PTHD4_HUMAN Decreases Expression [16]
Chondroitin sulfate synthase 3 (CHSY3) OT8ERGMH CHSS3_HUMAN Increases Expression [16]
Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 (SLC46A3) OTEMDLPS S46A3_HUMAN Increases Expression [16]
Target of Nesh-SH3 (ABI3BP) OTW8DN50 TARSH_HUMAN Increases Expression [16]
MOB kinase activator 3B (MOB3B) OTZJQG1D MOB3B_HUMAN Increases Expression [16]
SEC14 domain and spectrin repeat-containing protein 1 (SESTD1) OTHH06X8 SESD1_HUMAN Increases Expression [16]
Proline-rich protein 15 (PRR15) OTJHSY8G PRR15_HUMAN Increases Expression [16]
Neuron navigator 3 (NAV3) OT97M1TR NAV3_HUMAN Decreases Expression [16]
Beta-galactosidase-1-like protein 2 (GLB1L2) OTLI6HCH GLBL2_HUMAN Increases Expression [16]
CD302 antigen (CD302) OTX580VU CD302_HUMAN Increases Expression [16]
Myocardin (MYOCD) OTSJNHTH MYCD_HUMAN Increases Expression [16]
Protein APCDD1 (APCDD1) OTV9AD0L APCD1_HUMAN Increases Expression [16]
Protein odd-skipped-related 2 (OSR2) OTYG371T OSR2_HUMAN Increases Expression [16]
Protein FAM43A (FAM43A) OT5RPQRE FA43A_HUMAN Decreases Expression [16]
Rho GTPase-activating protein 18 (ARHGAP18) OTYMJP6H RHG18_HUMAN Decreases Expression [16]
Chemokine-like protein TAFA-2 (TAFA2) OTU6WP6J TAFA2_HUMAN Increases Expression [16]
Actin filament-associated protein 1-like 2 (AFAP1L2) OTJBI0VN AF1L2_HUMAN Decreases Expression [16]
Sterile alpha motif domain-containing protein 12 (SAMD12) OTIFG9O6 SAM12_HUMAN Decreases Expression [16]
Coiled-coil domain-containing protein 71L (CCDC71L) OT7ECVUW CC71L_HUMAN Decreases Expression [16]
Kelch-like protein 23 (KLHL23) OT2UVSD2 KLH23_HUMAN Increases Expression [16]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) OTY829Z3 ABHD5_HUMAN Increases Expression [16]
Voltage-dependent calcium channel gamma-like subunit (TMEM37) OT317PEL CCGL_HUMAN Increases Expression [16]
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (ST8SIA1) OTGND2YZ SIA8A_HUMAN Decreases Expression [16]
Serine palmitoyltransferase small subunit A (SPTSSA) OT2PNKOP SPTSA_HUMAN Increases Expression [16]
Fermitin family homolog 2 (FERMT2) OTZNPWWX FERM2_HUMAN Increases Expression [16]
SPRY domain-containing SOCS box protein 1 (SPSB1) OTGY26U4 SPSB1_HUMAN Increases Expression [16]
Synaptotagmin-like protein 4 (SYTL4) OT7MX5IK SYTL4_HUMAN Increases Expression [16]
Isochorismatase domain-containing protein 1 (ISOC1) OTAO7Z87 ISOC1_HUMAN Decreases Expression [16]
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) OTCAY35T CYFP2_HUMAN Decreases Expression [16]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) OTY5HZN5 LRIG1_HUMAN Increases Expression [16]
Lysyl oxidase homolog 4 (LOXL4) OT6XY2JL LOXL4_HUMAN Decreases Expression [16]
Solute carrier family 41 member 2 (SLC41A2) OT8EB4TF S41A2_HUMAN Increases Expression [16]
Guanylate-binding protein 4 (GBP4) OTSPNGKX GBP4_HUMAN Decreases Expression [16]
Osteomodulin (OMD) OTFRELBB OMD_HUMAN Increases Expression [16]
EF-hand domain-containing protein D1 (EFHD1) OTL5INE4 EFHD1_HUMAN Increases Expression [16]
Sorbin and SH3 domain-containing protein 1 (SORBS1) OTWH8762 SRBS1_HUMAN Increases Expression [16]
Atypical chemokine receptor 4 (ACKR4) OTZPWT2N ACKR4_HUMAN Decreases Expression [16]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1) OT9HYT7A PLCB1_HUMAN Decreases Expression [16]
SNF-related serine/threonine-protein kinase (SNRK) OTX0OPHO SNRK_HUMAN Decreases Expression [16]
G-protein coupled receptor family C group 5 member B (GPRC5B) OTF3S5E3 GPC5B_HUMAN Increases Expression [16]
E3 ISG15--protein ligase HERC5 (HERC5) OTZ5PR39 HERC5_HUMAN Decreases Expression [16]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Increases Expression [16]
Potassium channel subfamily K member 6 (KCNK6) OTCY281R KCNK6_HUMAN Increases Expression [16]
Atrial natriuretic peptide-converting enzyme (CORIN) OT4SK7DK CORIN_HUMAN Increases Expression [16]
LHFPL tetraspan subfamily member 6 protein (LHFPL6) OTY6LHJY LHPL6_HUMAN Increases Expression [16]
Mitogen-activated protein kinase kinase kinase 4 (MAP3K4) OTTFQVRC M3K4_HUMAN Increases Expression [16]
Protein FAM181B (FAM181B) OTGZHJ7K F181B_HUMAN Increases Expression [17]
Ribonuclease T2 (RNASET2) OTWY64L7 RNT2_HUMAN Decreases Expression [17]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG) OTUX45ZF MFNG_HUMAN Increases Expression [17]
Calmegin (CLGN) OTEWVFQV CLGN_HUMAN Decreases Expression [17]
Polyunsaturated fatty acid lipoxygenase ALOX15B (ALOX15B) OTWQQ08W LX15B_HUMAN Increases Expression [17]
Cationic amino acid transporter 4 (SLC7A4) OTAVC6QS CTR4_HUMAN Decreases Expression [17]
Keratin, type II cuticular Hb6 (KRT86) OT93MMAK KRT86_HUMAN Increases Expression [17]
Myelin protein zero-like protein 2 (MPZL2) OTKFNDUI MPZL2_HUMAN Decreases Expression [17]
Organic cation/carnitine transporter 2 (SLC22A5) OTC36TYB S22A5_HUMAN Increases Expression [17]
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (PDE9A) OT4U3QHF PDE9A_HUMAN Decreases Expression [17]
Sorbin and SH3 domain-containing protein 2 (SORBS2) OTJSX44Y SRBS2_HUMAN Decreases Expression [17]
Fibrinogen beta chain (FGB) OT6RKLI9 FIBB_HUMAN Increases Expression [17]
Sodium/potassium-transporting ATPase subunit beta-1 (ATP1B1) OTTO6ZP4 AT1B1_HUMAN Decreases Expression [17]
Plasma protease C1 inhibitor (SERPING1) OT6CVN45 IC1_HUMAN Increases Expression [17]
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) OTWJTCRK PCCA_HUMAN Decreases Expression [17]
Keratin, type II cytoskeletal 8 (KRT8) OTTM4X11 K2C8_HUMAN Decreases Expression [17]
Annexin A3 (ANXA3) OTDD8OI7 ANXA3_HUMAN Decreases Expression [17]
Hematopoietic lineage cell-specific protein (HCLS1) OTX7WGYN HCLS1_HUMAN Increases Expression [17]
Interferon gamma receptor 1 (IFNGR1) OTCTQBWW INGR1_HUMAN Decreases Expression [17]
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) OT6MFOWF TGM2_HUMAN Increases Expression [17]
Endothelin receptor type B (EDNRB) OTLLZV3P EDNRB_HUMAN Increases Expression [17]
5-hydroxytryptamine receptor 2A (HTR2A) OTWXJX0M 5HT2A_HUMAN Increases Expression [17]
Glutathione hydrolase 5 proenzyme (GGT5) OTDJYEO7 GGT5_HUMAN Increases Expression [17]
GMP reductase 1 (GMPR) OTERWHYM GMPR1_HUMAN Decreases Expression [17]
Amiloride-sensitive sodium channel subunit alpha (SCNN1A) OTE2KVZV SCNNA_HUMAN Decreases Expression [17]
Retinoic acid receptor responder protein 1 (RARRES1) OTETUPP5 TIG1_HUMAN Increases Expression [17]
Cysteine-rich protein 1 (CRIP1) OT0EICG3 CRIP1_HUMAN Decreases Expression [17]
Lumican (LUM) OTSRC874 LUM_HUMAN Increases Expression [17]
Growth arrest-specific protein 1 (GAS1) OTKJXG52 GAS1_HUMAN Increases Expression [17]
Microfibril-associated glycoprotein 4 (MFAP4) OT5W64QY MFAP4_HUMAN Increases Expression [17]
Prokineticin-1 (PROK1) OT8S7RUG PROK1_HUMAN Increases Expression [17]
Ras-related protein Rab-15 (RAB15) OTU0GGR3 RAB15_HUMAN Decreases Expression [17]
FXYD domain-containing ion transport regulator 4 (FXYD4) OT06IH3H FXYD4_HUMAN Decreases Expression [17]
Rho-related GTP-binding protein RhoE (RND3) OTXMXPIH RND3_HUMAN Increases Expression [17]
Troponin C, slow skeletal and cardiac muscles (TNNC1) OT9A0FL4 TNNC1_HUMAN Decreases Expression [17]
Transducin-like enhancer protein 2 (TLE2) OT2KSZ9B TLE2_HUMAN Increases Expression [17]
NKG2-E type II integral membrane protein (KLRC3) OT9EPHV3 NKG2E_HUMAN Increases Expression [17]
Regulator of G-protein signaling 1 (RGS1) OTGXJYMG RGS1_HUMAN Increases Expression [17]
Ankyrin-3 (ANK3) OTJ3IRBP ANK3_HUMAN Decreases Expression [17]
Protein AF1q (MLLT11) OTG5RVHC AF1Q_HUMAN Increases Expression [17]
Multimerin-1 (MMRN1) OT7ZNYHT MMRN1_HUMAN Increases Expression [17]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) OTGTAGCV PPR1A_HUMAN Decreases Expression [17]
Calcium/calmodulin-dependent protein kinase type II subunit beta (CAMK2B) OTS9YK3E KCC2B_HUMAN Decreases Expression [17]
Hyaluronan-binding protein 2 (HABP2) OTAUIPW0 HABP2_HUMAN Increases Expression [17]
Receptor-type tyrosine-protein phosphatase R (PTPRR) OT790UA2 PTPRR_HUMAN Increases Expression [17]
Adipogenesis regulatory factor (ADIRF) OTTJP8D4 ADIRF_HUMAN Decreases Expression [17]
Laminin subunit alpha-4 (LAMA4) OTHI7TA0 LAMA4_HUMAN Increases Expression [17]
Diacylglycerol kinase delta (DGKD) OTNI8HAH DGKD_HUMAN Decreases Expression [17]
Tumor protein D53 (TPD52L1) OTSA6U0I TPD53_HUMAN Decreases Expression [17]
Protein FAM110C (FAM110C) OTI5V72M F110C_HUMAN Decreases Expression [17]
Inhibitory synaptic factor 1 (INSYN1) OTPKEFNC INSY1_HUMAN Decreases Expression [17]
Filamin A-interacting protein 1-like (FILIP1L) OTPY8IMS FIL1L_HUMAN Increases Expression [17]
Keratinocyte-associated protein 3 (KRTCAP3) OTB24J5O KCP3_HUMAN Decreases Expression [17]
OCIA domain-containing protein 2 (OCIAD2) OTSWB4SZ OCAD2_HUMAN Decreases Expression [17]
Calcium homeostasis modulator protein 6 (CALHM6) OTLX9B4Y CAHM6_HUMAN Increases Expression [17]
Transcription factor HES-5 (HES5) OTW7JEHV HES5_HUMAN Decreases Expression [17]
Mitochondrial amidoxime-reducing component 1 (MTARC1) OTNBE033 MARC1_HUMAN Decreases Expression [17]
Carboxylesterase 4A (CES4A) OT0Q5JEU EST4A_HUMAN Decreases Expression [17]
TMF-regulated nuclear protein 1 (TRNP1) OTYYV8LN TRNP1_HUMAN Increases Expression [17]
Ribosomal protein eL22-like (RPL22L1) OTNWGF5C RL22L_HUMAN Increases Expression [17]
Surfactant-associated protein 2 (SFTA2) OTVRIUIV SFTA2_HUMAN Decreases Expression [17]
Isoaspartyl peptidase/L-asparaginase (ASRGL1) OTNGNRBA ASGL1_HUMAN Decreases Expression [17]
RAS guanyl-releasing protein 2 (RASGRP2) OTABVLVQ GRP2_HUMAN Increases Expression [17]
Calcium-dependent secretion activator 2 (CADPS2) OTV1FW0M CAPS2_HUMAN Increases Expression [17]
Enoyl-CoA hydratase domain-containing protein 2, mitochondrial (ECHDC2) OTL0DWCO ECHD2_HUMAN Decreases Expression [17]
Transmembrane protein 139 (TMEM139) OTZA6I9L TM139_HUMAN Decreases Expression [17]
Beta/gamma crystallin domain-containing protein 2 (CRYBG2) OTTPFG2M CRBG2_HUMAN Decreases Expression [17]
Ankyrin repeat domain-containing protein 35 (ANKRD35) OTFF5JP6 ANR35_HUMAN Decreases Expression [17]
Xylosyl- and glucuronyltransferase LARGE2 (LARGE2) OT5BZS3J LARG2_HUMAN Decreases Expression [17]
Mitochondrial basic amino acids transporter (SLC25A29) OT09PIFE S2529_HUMAN Decreases Expression [17]
Carbohydrate sulfotransferase 4 (CHST4) OTESMIW5 CHST4_HUMAN Decreases Expression [17]
SLAIN motif-containing protein 1 (SLAIN1) OTMT25MN SLAI1_HUMAN Decreases Expression [17]
Transient receptor potential cation channel subfamily M member 4 (TRPM4) OT354X8E TRPM4_HUMAN Decreases Expression [17]
E3 ubiquitin-protein ligase SH3RF2 (SH3RF2) OT2IVOK4 SH3R2_HUMAN Decreases Expression [17]
Glucose-6-phosphate exchanger SLC37A2 (SLC37A2) OTH77FBE G6PT3_HUMAN Decreases Expression [17]
DEP domain-containing protein 1B (DEPDC1B) OTMVFOT1 DEP1B_HUMAN Increases Expression [17]
Transcription factor GATA-6 (GATA6) OTO2BC0F GATA6_HUMAN Increases Expression [17]
Homogentisate 1,2-dioxygenase (HGD) OTTKLQOO HGD_HUMAN Decreases Expression [17]
Kazal-type serine protease inhibitor domain-containing protein 1 (KAZALD1) OTSFOX2H KAZD1_HUMAN Decreases Expression [17]
Cytosolic non-specific dipeptidase (CNDP2) OTJR9436 CNDP2_HUMAN Decreases Expression [17]
Glycosyltransferase 1 domain-containing protein 1 (GLT1D1) OTXW0WXJ GL1D1_HUMAN Increases Expression [17]
Protein orai-2 (ORAI2) OTYISRYH ORAI2_HUMAN Decreases Expression [17]
Leucine-rich repeat-containing protein 1 (LRRC1) OTSVD30Q LRRC1_HUMAN Decreases Expression [17]
Melanophilin (MLPH) OT7ADCXL MELPH_HUMAN Increases Expression [17]
PGAP2-interacting protein (CWH43) OTT3DPRH PG2IP_HUMAN Decreases Expression [17]
Kinetochore protein Spc25 (SPC25) OTCAS0OH SPC25_HUMAN Increases Expression [17]
Neurexin-3-beta (NRXN3) OTJ0I7HJ NRX3B_HUMAN Decreases Expression [17]
ABC-type oligopeptide transporter ABCB9 (ABCB9) OTSOBOL5 ABCB9_HUMAN Decreases Expression [17]
Carbohydrate sulfotransferase 11 (CHST11) OTNJJ5Q1 CHSTB_HUMAN Increases Expression [17]
Dual oxidase 1 (DUOX1) OTQ2AEW0 DUOX1_HUMAN Decreases Expression [17]
Transmembrane protein 45A (TMEM45A) OT54KJG6 TM45A_HUMAN Increases Expression [17]
Syntabulin (SYBU) OT3FQV7N SYBU_HUMAN Decreases Expression [17]
Probable ATP-dependent RNA helicase DDX43 (DDX43) OTK1RYSK DDX43_HUMAN Decreases Expression [17]
Transcription factor CP2-like protein 1 (TFCP2L1) OT7QIJ0X TF2L1_HUMAN Decreases Expression [17]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) OTV3Q0DS ATS9_HUMAN Increases Expression [17]
E3 ubiquitin-protein ligase CBL-C (CBLC) OT3RKZI9 CBLC_HUMAN Decreases Expression [17]
Protein NDRG2 (NDRG2) OT5L6KD7 NDRG2_HUMAN Decreases Expression [17]
Epididymis-specific alpha-mannosidase (MAN2B2) OTU9V3PE MA2B2_HUMAN Decreases Expression [17]
Sorting nexin-10 (SNX10) OT05B7BT SNX10_HUMAN Increases Expression [17]
Transcription factor E2F8 (E2F8) OTQKZGFP E2F8_HUMAN Decreases Expression [18]
Ras-related protein Rab-27B (RAB27B) OTPF9D0K RB27B_HUMAN Increases Expression [18]
Matrilin-2 (MATN2) OTVDR68G MATN2_HUMAN Increases Expression [18]
E3 ubiquitin-protein ligase Midline-1 (MID1) OTWN1PGU TRI18_HUMAN Decreases Expression [18]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [18]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [18]
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) OTZKOTDB ADA12_HUMAN Decreases Expression [18]
Mothers against decapentaplegic homolog 6 (SMAD6) OTUZZWUD SMAD6_HUMAN Decreases Expression [18]
Protein sprouty homolog 1 (SPRY1) OT764FXI SPY1_HUMAN Increases Expression [18]
Protein regulator of cytokinesis 1 (PRC1) OTHD0XS0 PRC1_HUMAN Decreases Expression [18]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Decreases Expression [18]
Monocarboxylate transporter 2 (SLC16A7) OT7OI36B MOT2_HUMAN Decreases Expression [18]
Thiamine transporter 1 (SLC19A2) OTH5SB0M S19A2_HUMAN Increases Expression [18]
Hyaluronan mediated motility receptor (HMMR) OT4M0JTZ HMMR_HUMAN Decreases Expression [18]
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) OT3EDGXO TNR21_HUMAN Increases Expression [18]
SEC14-like protein 2 (SEC14L2) OTJST64D S14L2_HUMAN Increases Expression [18]
G2/mitotic-specific cyclin-B2 (CCNB2) OTIEXTDK CCNB2_HUMAN Decreases Expression [18]
Kinesin-like protein KIF20A (KIF20A) OTXOQHE0 KI20A_HUMAN Decreases Expression [18]
Chromosome-associated kinesin KIF4A (KIF4A) OT3UWL7D KIF4A_HUMAN Decreases Expression [18]
Cholesterol 25-hydroxylase (CH25H) OT9S2BSW CH25H_HUMAN Decreases Expression [18]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Increases Expression [18]
Thymidine kinase, cytosolic (TK1) OTY5JFM1 KITH_HUMAN Decreases Expression [18]
Metallothionein-1F (MT1F) OTZVUYG1 MT1F_HUMAN Increases Expression [18]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Decreases Expression [18]
Inhibin beta B chain (INHBB) OT2QLD11 INHBB_HUMAN Increases Expression [18]
Thymosin beta-15A (TMSB15A) OTSBWCES TB15A_HUMAN Decreases Expression [18]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [18]
Hyaluronan and proteoglycan link protein 1 (HAPLN1) OTXWR9TJ HPLN1_HUMAN Decreases Expression [18]
Microtubule-associated protein 2 (MAP2) OT6UYT3X MTAP2_HUMAN Decreases Expression [18]
Myosin light chain 6B (MYL6B) OTWTRGT7 MYL6B_HUMAN Decreases Expression [18]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Decreases Expression [18]
Lamin-B1 (LMNB1) OT100T3P LMNB1_HUMAN Decreases Expression [18]
Anosmin-1 (ANOS1) OTZJT4KN KALM_HUMAN Decreases Expression [18]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Decreases Expression [18]
Pentraxin-related protein PTX3 (PTX3) OTPXHRKU PTX3_HUMAN Increases Expression [18]
G0/G1 switch protein 2 (G0S2) OT8FL49L G0S2_HUMAN Increases Expression [18]
DNA replication licensing factor MCM5 (MCM5) OTAHLB62 MCM5_HUMAN Decreases Expression [18]
Ribonuclease 4 (RNASE4) OTA5SZLC RNAS4_HUMAN Increases Expression [18]
Myosin-10 (MYH10) OTXN2WXS MYH10_HUMAN Decreases Expression [18]
Eukaryotic translation initiation factor 1 (EIF1) OTB4GZ0V EIF1_HUMAN Increases Expression [18]
5-hydroxytryptamine receptor 2B (HTR2B) OTM1AD9J 5HT2B_HUMAN Decreases Expression [18]
Neutral amino acid transporter A (SLC1A4) OTVODHAE SATT_HUMAN Increases Expression [18]
Tissue factor pathway inhibitor 2 (TFPI2) OTZCRWOR TFPI2_HUMAN Increases Expression [18]
MARCKS-related protein (MARCKSL1) OT13J2FM MRP_HUMAN Decreases Expression [18]
Histone H3-like centromeric protein A (CENPA) OT0NEJ4X CENPA_HUMAN Decreases Expression [18]
Calponin-1 (CNN1) OTVPG39Z CNN1_HUMAN Decreases Expression [18]
Serine/threonine-protein kinase Nek2 (NEK2) OT1H27HO NEK2_HUMAN Decreases Expression [18]
Sodium/myo-inositol cotransporter (SLC5A3) OT6FY2KA SC5A3_HUMAN Decreases Expression [18]
Smoothelin (SMTN) OT4R2TYK SMTN_HUMAN Decreases Expression [18]
Paired mesoderm homeobox protein 1 (PRRX1) OTTZK5G8 PRRX1_HUMAN Decreases Expression [18]
Period circadian protein homolog 3 (PER3) OTVKYVJA PER3_HUMAN Decreases Expression [18]
Protein S100-A10 (S100A10) OTI71243 S10AA_HUMAN Increases Expression [18]
Actin, alpha cardiac muscle 1 (ACTC1) OTJU04B1 ACTC_HUMAN Decreases Expression [18]
Interleukin-13 receptor subunit alpha-1 (IL13RA1) OT59OYXP I13R1_HUMAN Decreases Expression [18]
Cyclic AMP-responsive element-binding protein 5 (CREB5) OTJDUJPI CREB5_HUMAN Decreases Expression [18]
A-kinase anchor protein 12 (AKAP12) OTCVRDDX AKA12_HUMAN Increases Expression [18]
Activin receptor type-1 (ACVR1) OT4JATFE ACVR1_HUMAN Decreases Expression [18]
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) OTOA8WU2 PDE4B_HUMAN Decreases Expression [18]
Homeobox protein DLX-2 (DLX2) OTKC2DQ0 DLX2_HUMAN Decreases Expression [18]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1) OTNYXOZO KCMA1_HUMAN Increases Expression [18]
Growth factor receptor-bound protein 10 (GRB10) OTCKXGRC GRB10_HUMAN Increases Expression [18]
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) OT70Z4II ADAM9_HUMAN Increases Expression [18]
Ras GTPase-activating-like protein IQGAP2 (IQGAP2) OTX2UA7P IQGA2_HUMAN Increases Expression [18]
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (PDE1C) OT5VWYPI PDE1C_HUMAN Decreases Expression [18]
PCNA-associated factor (PCLAF) OTMVIOUU PAF15_HUMAN Decreases Expression [18]
Kinesin-like protein KIF14 (KIF14) OTXHT4JM KIF14_HUMAN Decreases Expression [18]
Disks large-associated protein 5 (DLGAP5) OTWCN39U DLGP5_HUMAN Decreases Expression [18]
Cysteine and glycine-rich protein 2 (CSRP2) OT4SW0HI CSRP2_HUMAN Decreases Expression [18]
Cyclin-dependent kinase inhibitor 3 (CDKN3) OTBE3H07 CDKN3_HUMAN Decreases Expression [18]
Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2) OTJ8LX4N PCKGM_HUMAN Increases Expression [18]
Serine protease inhibitor Kazal-type 13 (SPINK13) OTEU2OSU ISK13_HUMAN Increases Expression [18]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1) OT6Z1L2E PLCH1_HUMAN Decreases Expression [18]
Centrosomal protein of 55 kDa (CEP55) OTGSG2PA CEP55_HUMAN Decreases Expression [18]
Shugoshin 2 (SGO2) OTNGJDS8 SGO2_HUMAN Decreases Expression [18]
Transmembrane protein 164 (TMEM164) OTSIZY2T TM164_HUMAN Increases Expression [18]
Mesenteric estrogen-dependent adipogenesis protein (MEDAG) OT6BK4EI MEDAG_HUMAN Increases Expression [18]
Formin-1 (FMN1) OT9CID5R FMN1_HUMAN Decreases Expression [18]
Pleckstrin homology domain-containing family A member 7 (PLEKHA7) OTNUMAZ0 PKHA7_HUMAN Increases Expression [18]
Potassium channel subfamily T member 2 (KCNT2) OTFTL0BQ KCNT2_HUMAN Increases Expression [18]
Golgi-associated kinase 1B (GASK1B) OT2HPHEI GAK1B_HUMAN Increases Expression [18]
NF-X1-type zinc finger protein NFXL1 (NFXL1) OT2Y5D15 NFXL1_HUMAN Increases Expression [18]
Centromere protein U (CENPU) OTQ4TZRS CENPU_HUMAN Decreases Expression [18]
MAM domain-containing protein 2 (MAMDC2) OT4GICNY MAMC2_HUMAN Increases Expression [18]
LisH domain-containing protein ARMC9 (ARMC9) OT0MZER2 ARMC9_HUMAN Decreases Expression [18]
Retrotransposon-derived protein PEG10 (PEG10) OTWD2278 PEG10_HUMAN Decreases Expression [18]
Ras GTPase-activating-like protein IQGAP3 (IQGAP3) OT4RZV2M IQGA3_HUMAN Decreases Expression [18]
Liprin-beta-1 (PPFIBP1) OTRA2S7B LIPB1_HUMAN Decreases Expression [18]
GAS2-like protein 3 (GAS2L3) OTWPVI29 GA2L3_HUMAN Decreases Expression [18]
Sodium leak channel NALCN (NALCN) OTWY7DS0 NALCN_HUMAN Increases Expression [18]
Dedicator of cytokinesis protein 4 (DOCK4) OTH3XY8B DOCK4_HUMAN Decreases Expression [18]
Leucine-rich repeat-containing protein 17 (LRRC17) OT3NZSX3 LRC17_HUMAN Decreases Expression [18]
Junction-mediating and -regulatory protein (JMY) OTH5FFVK JMY_HUMAN Decreases Expression [18]
Kinetochore scaffold 1 (KNL1) OT4Q3LHV KNL1_HUMAN Decreases Expression [18]
Pleckstrin homology-like domain family A member 1 (PHLDA1) OTFTWMIQ PHLA1_HUMAN Increases Expression [18]
Potassium voltage-gated channel subfamily E member 4 (KCNE4) OTNYW0OL KCNE4_HUMAN Increases Expression [18]
Cytoskeleton-associated protein 2 (CKAP2) OTCLTC0J CKAP2_HUMAN Decreases Expression [18]
E3 ubiquitin-protein ligase MYLIP (MYLIP) OTL0PFGV MYLIP_HUMAN Decreases Expression [18]
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) OTXGJ8N1 P55G_HUMAN Decreases Expression [18]
Protein NDRG1 (NDRG1) OTVO66BO NDRG1_HUMAN Increases Expression [18]
BTB/POZ domain-containing protein KCTD12 (KCTD12) OTPYKT4Z KCD12_HUMAN Increases Expression [18]
Terminal nucleotidyltransferase 5A (TENT5A) OTSYF511 TET5A_HUMAN Increases Expression [18]
Beta-galactoside alpha-2,6-sialyltransferase 2 (ST6GAL2) OTXIBF4D SIAT2_HUMAN Decreases Expression [18]
Lymphokine-activated killer T-cell-originated protein kinase (PBK) OT5Z27TW TOPK_HUMAN Decreases Expression [18]
FYVE, RhoGEF and PH domain-containing protein 4 (FGD4) OTYXJQCW FGD4_HUMAN Increases Expression [18]
Sterile alpha motif domain-containing protein 11 (SAMD11) OT6WRQOX SAM11_HUMAN Decreases Expression [18]
Discoidin, CUB and LCCL domain-containing protein 2 (DCBLD2) OTB71I02 DCBD2_HUMAN Decreases Expression [18]
Hemicentin-1 (HMCN1) OTLZAS0P HMCN1_HUMAN Decreases Expression [18]
Myeloid-associated differentiation marker (MYADM) OTZTZI7P MYADM_HUMAN Increases Expression [18]
Cell division cycle-associated protein 3 (CDCA3) OTUI8QK3 CDCA3_HUMAN Decreases Expression [18]
Neuronal PAS domain-containing protein 2 (NPAS2) OTMRT2TS NPAS2_HUMAN Increases Expression [18]
Condensin complex subunit 3 (NCAPG) OT1AI9EO CND3_HUMAN Decreases Expression [18]
Potassium voltage-gated channel subfamily S member 3 (KCNS3) OTHDD9F6 KCNS3_HUMAN Increases Expression [18]
Dysbindin domain-containing protein 2 (DBNDD2) OT9RI580 DBND2_HUMAN Increases Expression [18]
Transmembrane protein 204 (TMEM204) OT7X11D9 TM204_HUMAN Increases Expression [18]
Cell division cycle-associated protein 7 (CDCA7) OT12HDZY CDCA7_HUMAN Decreases Expression [18]
Asporin (ASPN) OTYJM80N ASPN_HUMAN Increases Expression [18]
Nucleolar and spindle-associated protein 1 (NUSAP1) OT85HIJ5 NUSAP_HUMAN Decreases Expression [18]
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase (B3GNT5) OTA0DE43 B3GN5_HUMAN Increases Expression [18]
NF-kappa-B inhibitor zeta (NFKBIZ) OTU728KS IKBZ_HUMAN Increases Expression [18]
Small integral membrane protein 3 (SMIM3) OTWPK14C SMIM3_HUMAN Increases Expression [18]
Transmembrane 6 superfamily member 1 (TM6SF1) OTQR4I2N TM6S1_HUMAN Increases Expression [18]
Rac GTPase-activating protein 1 (RACGAP1) OTQE8IEH RGAP1_HUMAN Decreases Expression [18]
Coiled-coil domain-containing protein 68 (CCDC68) OT4KF6TL CCD68_HUMAN Increases Expression [18]
Tumor protein 63 (TP63) OT0WOOKQ P63_HUMAN Decreases Expression [18]
Kinesin-like protein KIF13B (KIF13B) OTAFS1YV KI13B_HUMAN Increases Expression [18]
Anillin (ANLN) OTXJY54C ANLN_HUMAN Decreases Expression [18]
Matrix-remodeling-associated protein 5 (MXRA5) OTXZBWCU MXRA5_HUMAN Decreases Expression [18]
Lymphoid-specific helicase (HELLS) OTVVV668 HELLS_HUMAN Decreases Expression [18]
Tumor necrosis factor receptor superfamily member 19 (TNFRSF19) OTTVT4MB TNR19_HUMAN Decreases Expression [18]
Protein diaphanous homolog 3 (DIAPH3) OTPOT23F DIAP3_HUMAN Decreases Expression [18]
Structural maintenance of chromosomes protein 4 (SMC4) OTEJE6AG SMC4_HUMAN Decreases Expression [18]
SERTA domain-containing protein 4 (SERTAD4) OTZ1GUD9 SRTD4_HUMAN Decreases Expression [18]
G2 and S phase-expressed protein 1 (GTSE1) OTPP742Z GTSE1_HUMAN Decreases Expression [18]
Denticleless protein homolog (DTL) OTC29RYE DTL_HUMAN Decreases Expression [18]
Contactin-3 (CNTN3) OTC1274J CNTN3_HUMAN Increases Expression [18]
Prostaglandin F2 receptor negative regulator (PTGFRN) OTBG4SA2 FPRP_HUMAN Decreases Expression [18]
Fibulin-5 (FBLN5) OTLVNZ8U FBLN5_HUMAN Increases Expression [18]
DNA dC->dU-editing enzyme APOBEC-3B (APOBEC3B) OTHLNI51 ABC3B_HUMAN Decreases Expression [18]
Targeting protein for Xklp2 (TPX2) OTWLJYH0 TPX2_HUMAN Decreases Expression [18]
Dynamin-3 (DNM3) OTDMUGCR DYN3_HUMAN Decreases Expression [18]
Nuclear protein AMMECR1 (AMMECR1) OTWMQ67T AMMR1_HUMAN Increases Expression [18]
Fatty acid desaturase 3 (FADS3) OT9RVXGE FADS3_HUMAN Increases Expression [18]
Calcium-activated potassium channel subunit beta-2 (KCNMB2) OTBXUQGK KCMB2_HUMAN Decreases Expression [18]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) OTTLD0KB SQOR_HUMAN Increases Expression [18]
Diacylglycerol kinase beta (DGKB) OTTT9SZJ DGKB_HUMAN Decreases Expression [18]
Influenza virus NS1A-binding protein (IVNS1ABP) OTYHL4I7 NS1BP_HUMAN Decreases Expression [18]
17-beta-hydroxysteroid dehydrogenase type 2 (HSD17B2) OT3K7HY5 DHB2_HUMAN Decreases Expression [45]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Decreases Expression [45]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Activity [54]
Basic helix-loop-helix ARNT-like protein 1 (BMAL1) OTMI12L2 BMAL1_HUMAN Increases Expression [55]
Gamma-aminobutyric acid receptor subunit pi (GABRP) OTGKA8WS GBRP_HUMAN Increases Expression [56]
Suppressor of cytokine signaling 2 (SOCS2) OTBPNKJQ SOCS2_HUMAN Decreases Expression [57]
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) OTPGHZB9 IFIT3_HUMAN Increases Expression [57]
Period circadian protein homolog 2 (PER2) OTU2B1DJ PER2_HUMAN Increases Expression [55]
Defensin beta 4A (DEFB4A) OTQEI15K DFB4A_HUMAN Increases Expression [58]
Interleukin-1 receptor-associated kinase-like 2 (IRAK2) OT6Y1QZN IRAK2_HUMAN Increases Expression [59]
Left-right determination factor 1 (LEFTY1) OT51HVC4 LFTY1_HUMAN Increases Expression [60]
Serine protease 23 (PRSS23) OT6DQAM1 PRS23_HUMAN Decreases Expression [61]
Neuroendocrine secretory protein 55 (GNAS) OTMH8BKJ GNAS3_HUMAN Increases Expression [62]
C-X-C motif chemokine 14 (CXCL14) OTM189TA CXL14_HUMAN Increases Expression [63]
Prothrombin (F2) OTNFSM49 THRB_HUMAN Increases Expression [64]
2'-5'-oligoadenylate synthase 1 (OAS1) OT8ZLOCY OAS1_HUMAN Increases Expression [57]
Antithrombin-III (SERPINC1) OTDFATG0 ANT3_HUMAN Decreases Expression [64]
Metalloproteinase inhibitor 1 (TIMP1) OTOXC51H TIMP1_HUMAN Increases Expression [65]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Decreases Expression [66]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Phosphorylation [49]
Sex hormone-binding globulin (SHBG) OTPWU5IW SHBG_HUMAN Affects Binding [67]
Tetranectin (CLEC3B) OTFD29NF TETN_HUMAN Increases Expression [65]
Pulmonary surfactant-associated protein B (SFTPB) OTOHS07E PSPB_HUMAN Increases Expression [68]
Stromelysin-1 (MMP3) OTGBI74Z MMP3_HUMAN Decreases Expression [60]
Guanine nucleotide-binding protein G(i) subunit alpha-3 (GNAI3) OT89UWAR GNAI3_HUMAN Decreases Expression [62]
Interleukin-6 receptor subunit alpha (IL6R) OTCQL07Z IL6RA_HUMAN Decreases Expression [57]
Matrilysin (MMP7) OTVT3SEJ MMP7_HUMAN Decreases Secretion [69]
Stromelysin-2 (MMP10) OTJDWW8Q MMP10_HUMAN Increases Expression [65]
Growth-regulated alpha protein (CXCL1) OT3WCTZV GROA_HUMAN Decreases Expression [70]
Myb-related protein A (MYBL1) OTBJMC2P MYBA_HUMAN Increases Expression [71]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) OTA675TJ GTR1_HUMAN Increases Expression [72]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Increases Expression [57]
HLA class I histocompatibility antigen, alpha chain E (HLA-E) OTX1CTFB HLAE_HUMAN Increases Expression [73]
Aggrecan core protein (ACAN) OTUOCW8K PGCA_HUMAN Increases Expression [74]
Integrin beta-4 (ITGB4) OT28UK84 ITB4_HUMAN Increases Expression [65]
HLA class I histocompatibility antigen, alpha chain G (HLA-G) OTMLK1KN HLAG_HUMAN Increases Expression [75]
Nucleoside diphosphate kinase B (NME2) OTCYGLHV NDKB_HUMAN Increases Expression [76]
Potassium voltage-gated channel subfamily A member 5 (KCNA5) OTHI2N71 KCNA5_HUMAN Decreases Activity [77]
Fibulin-1 (FBLN1) OT5MHHOP FBLN1_HUMAN Increases Expression [78]
Integrin alpha-3 (ITGA3) OTBCH21D ITA3_HUMAN Increases Expression [65]
HLA class I histocompatibility antigen, alpha chain F (HLA-F) OT76CM19 HLAF_HUMAN Increases Expression [73]
Gamma-aminobutyric acid receptor subunit alpha-5 (GABRA5) OTBIKWQT GBRA5_HUMAN Decreases Expression [79]
Metalloproteinase inhibitor 3 (TIMP3) OTDGQAD1 TIMP3_HUMAN Decreases Expression [60]
Protein DEK (DEK) OTYCJ5H6 DEK_HUMAN Increases Expression [80]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [81]
Collagen alpha-1(XV) chain (COL15A1) OTTFKK18 COFA1_HUMAN Increases Expression [65]
Megakaryocyte-associated tyrosine-protein kinase (MATK) OTVOJJLJ MATK_HUMAN Increases Expression [49]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [81]
Gamma-aminobutyric acid receptor subunit alpha-2 (GABRA2) OT9TZ2E0 GBRA2_HUMAN Increases Expression [79]
Signal transducer and activator of transcription 5B (STAT5B) OTZVPEBT STA5B_HUMAN Increases Expression [82]
Neutrophil defensin 1 (DEFA1) OT5N1B9B DEF1_HUMAN Increases Expression [59]
Neutrophil defensin 3 (DEFA3) OTO3N8E1 DEF3_HUMAN Increases Expression [59]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Increases Expression [83]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) OT1SLUZH TSG6_HUMAN Decreases Expression [84]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Decreases Activity [70]
Semaphorin-3B (SEMA3B) OTCZCPMS SEM3B_HUMAN Increases Expression [85]
Pappalysin-1 (PAPPA) OTTTG9PG PAPP1_HUMAN Decreases Expression [61]
Semaphorin-3F (SEMA3F) OTQFMS8S SEM3F_HUMAN Increases Expression [85]
Metastasis-associated protein MTA1 (MTA1) OTBHW3S9 MTA1_HUMAN Increases Expression [83]
28 kDa heat- and acid-stable phosphoprotein (PDAP1) OTJSWMOD HAP28_HUMAN Increases Expression [83]
Laminin subunit beta-3 (LAMB3) OTFPU6W8 LAMB3_HUMAN Increases Expression [65]
Interleukin-27 subunit beta (EBI3) OT0LF3D7 IL27B_HUMAN Increases Expression [57]
Hypermethylated in cancer 1 protein (HIC1) OTI9TWY4 HIC1_HUMAN Increases Expression [57]
Interleukin-13 receptor subunit alpha-2 (IL13RA2) OTPC2G0X I13R2_HUMAN Decreases Expression [84]
Sonic hedgehog protein (SHH) OTOG2BXF SHH_HUMAN Decreases Expression [84]
Rapamycin-insensitive companion of mTOR (RICTOR) OTCC58QJ RICTR_HUMAN Decreases Expression [86]
Thrombospondin type-1 domain-containing protein 4 (THSD4) OTXDBMDC THSD4_HUMAN Increases Expression [61]
Cytochrome P450 4Z1 (CYP4Z1) OTKRGJBG CP4Z1_HUMAN Increases Expression [87]
Organic anion transporter 7 (SLC22A9) OTO4BJCC S22A9_HUMAN Decreases Activity [88]
E3 ubiquitin-protein ligase TRIM22 (TRIM22) OTJBLG5R TRI22_HUMAN Increases Expression [89]
Regulatory-associated protein of mTOR (RPTOR) OT4TQZ9F RPTOR_HUMAN Decreases Expression [86]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Decreases Expression [86]
Progesterone-induced-blocking factor 1 (PIBF1) OTCBT1A1 PIBF1_HUMAN Increases Expression [59]
Adiponectin receptor protein 1 (ADIPOR1) OT65ZFZN PAQR1_HUMAN Increases Expression [90]
Ankyrin repeat and SOCS box protein 2 (ASB2) OTF9LV7L ASB2_HUMAN Increases Expression [57]
Rho GTPase-activating protein 7 (DLC1) OTP8LMCR RHG07_HUMAN Increases Expression [76]
Zinc finger protein Gfi-1 (GFI1) OT9HB9H8 GFI1_HUMAN Increases Expression [57]
Gamma-aminobutyric acid receptor subunit gamma-3 (GABRG3) OTNWVXZR GBRG3_HUMAN Increases Expression [79]
Leucine zipper transcription factor-like protein 1 (LZTFL1) OTIEIOEW LZTL1_HUMAN Increases Expression [57]
Interleukin-17 receptor B (IL17RB) OT0KDNSF I17RB_HUMAN Decreases Expression [61]
Protein DEPP1 (DEPP1) OTB36PHJ DEPP1_HUMAN Increases Expression [91]
Interleukin-1 receptor-associated kinase 4 (IRAK4) OT9JTJWC IRAK4_HUMAN Increases Expression [59]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Increases Expression [92]
Syncytin-1 (ERVW-1) OTWV8DXJ SYCY1_HUMAN Increases Expression [93]
Tumor necrosis factor ligand superfamily member 13B (TNFSF13B) OTND26XR TN13B_HUMAN Increases Expression [57]
Pituitary adenylate cyclase-activating polypeptide (ADCYAP1) OT0LQH93 PACA_HUMAN Increases Abundance [25]
L-fucose kinase (FCSK) OT4NTHYO FCSK_HUMAN Affects Response To Substance [23]
Lutropin subunit beta (LHB) OT5GBOVJ LSHB_HUMAN Decreases Abundance [94]
Aldo-keto reductase family 1 member D1 (AKR1D1) OTBDJ6RL AK1D1_HUMAN Increases Reduction [95]
Follitropin subunit beta (FSHB) OTGLS283 FSHB_HUMAN Increases Abundance [96]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) OTNAZVKB 3BHS1_HUMAN Increases Chemical Synthesis [97]
Steroidogenic factor 1 (NR5A1) OTOULYR4 STF1_HUMAN Increases Abundance [98]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Increases Reduction [99]
Glycodelin (PAEP) OTQA0NV4 PAEP_HUMAN Increases Abundance [100]
Retinol-binding protein 1 (RBP1) OTRP1MFC RET1_HUMAN Increases ADR [24]
Lutropin-choriogonadotropic hormone receptor (LHCGR) OTSVIJ6I LSHR_HUMAN Increases ADR [24]
Carboxypeptidase Q (CPQ) OTTNZNLD CBPQ_HUMAN Affects Response To Substance [23]
Pro-opiomelanocortin (POMC) OTV41F7T COLI_HUMAN Increases Abundance [101]
Choriogonadotropin subunit beta 3 (CGB3) OTVM2SU3 CGB3_HUMAN Increases Abundance [102]
Aldo-keto reductase family 1 member C4 (AKR1C4) OTW2MMOF AK1C4_HUMAN Decreases Abundance [103]
Testis-expressed protein 12 (TEX12) OTXHQWTA TEX12_HUMAN Affects Response To Substance [23]
Liprin-beta-2 (PPFIBP2) OTXQO55Y LIPB2_HUMAN Affects Response To Substance [23]
Polypeptide N-acetylgalactosaminyltransferase 10 (GALNT10) OTZ6FDOL GLT10_HUMAN Affects Response To Substance [23]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Increases ADR [24]
------------------------------------------------------------------------------------
⏷ Show the Full List of 859 DOT(s)
Indication(s) of Aspirin
Disease Entry ICD 11 Status REF
Acute coronary syndrome BA41 Approved [7]
Adenomatous colon polyp N.A. Approved [7]
Back pain ME84.Z Approved [7]
Common cold CA00 Approved [7]
Headache 8A80-8A84 Approved [7]
Migraine disorder N.A. Approved [7]
Myocardial infarction BA41-BA43 Approved [8]
Osteoarthritis FA00-FA05 Approved [7]
Pain MG30-MG3Z Approved [9]
Cardiovascular disease BA00-BE2Z Phase 3 [9]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2/3 [10]
Colon cancer 2B90.Z Investigative [7]
Aspirin Interacts with 2 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Prostaglandin G/H synthase (COX) TTK0943 PGH1_HUMAN; PGH2_HUMAN Inhibitor [115]
HMG-CoA reductase (HMGCR) TTPADOQ HMDH_HUMAN Inhibitor [8]
------------------------------------------------------------------------------------
Aspirin Interacts with 4 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [116]
Organic anion transporter 2 (SLC22A7) DT0OC1Q S22A7_HUMAN Substrate [117]
Sodium-dependent phosphate transport protein 1 (SLC17A1) DT8ARWJ NPT1_HUMAN Substrate [118]
Probable small intestine urate exporter (SLC17A4) DTHE530 S17A4_HUMAN Substrate [119]
------------------------------------------------------------------------------------
Aspirin Interacts with 6 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Metabolism [120]
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Metabolism [121]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Metabolism [122]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [123]
N-acetyltransferase 2 (NAT2) DER7TA0 ARY2_HUMAN Metabolism [122]
UDP-glucuronosyltransferase 1A6 (UGT1A6) DESD26P UD16_HUMAN Metabolism [122]
------------------------------------------------------------------------------------
⏷ Show the Full List of 6 DME(s)
Aspirin Interacts with 361 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Arylamine N-acetyltransferase 2 (NAT2) OTBPDQOY ARY2_HUMAN Affects Response To Substance [124]
Solute carrier family 22 member 7 (SLC22A7) OTKTNH1W S22A7_HUMAN Decreases Activity [125]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [126]
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1) OTVVI3UI DQB1_HUMAN Increases ADR [127]
HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) OTW8JHU2 DPB1_HUMAN Increases ADR [127]
Solute carrier organic anion transporter family member 1B1 (SLCO1B1) OTNEN8QK SO1B1_HUMAN Increases ADR [128]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Decreases Expression [129]
Integrin alpha-IIb (ITGA2B) OT4Y17PY ITA2B_HUMAN Decreases Expression [130]
Testis-expressed basic protein 1 (TSBP1) OT5GE8IO TSBP1_HUMAN Increases ADR [131]
HLA class II histocompatibility antigen, DQ alpha 1 chain (HLA-DQA1) OTC6GISG DQA1_HUMAN Increases ADR [131]
Collagen alpha-1(XXVI) chain (COL26A1) OTMS7RNF COQA1_HUMAN Affects Response To Substance [132]
Laminin subunit alpha-1 (LAMA1) OTQZMP86 LAMA1_HUMAN Increases ADR [133]
Putative glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial (GATD3) OTBQRU82 GAL3B_HUMAN Increases Expression [104]
Anoctamin-9 (ANO9) OTQ2UM3M ANO9_HUMAN Increases Expression [104]
PH and SEC7 domain-containing protein 1 (PSD) OTUZIXUZ PSD1_HUMAN Increases Expression [104]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A) OTFBU4GD P3C2A_HUMAN Decreases Expression [104]
Protocadherin-17 (PCDH17) OTRK0M05 PCD17_HUMAN Increases Expression [104]
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) OT4AVU95 MYPT1_HUMAN Decreases Expression [104]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1) OT959A3A AT2A1_HUMAN Increases Expression [104]
Origin recognition complex subunit 4 (ORC4) OT3ACTST ORC4_HUMAN Increases Expression [104]
85/88 kDa calcium-independent phospholipase A2 (PLA2G6) OT5FL0WU PLPL9_HUMAN Increases Expression [104]
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) OTSQGLSB TI17B_HUMAN Increases Expression [104]
Astrotactin-2 (ASTN2) OTF0W2FJ ASTN2_HUMAN Increases Expression [104]
Hyaluronan mediated motility receptor (HMMR) OT4M0JTZ HMMR_HUMAN Increases Expression [104]
Trafficking protein particle complex subunit 6A (TRAPPC6A) OT0ZRV5C TPC6A_HUMAN Increases Expression [104]
DNA topoisomerase 3-beta-1 (TOP3B) OTNFEUOO TOP3B_HUMAN Increases Expression [104]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [104]
Salivary acidic proline-rich phosphoprotein 1/2 (PRH1) OTQZ6HX0 PRPC_HUMAN Decreases Expression [104]
Ribonuclease pancreatic (RNASE1) OTKZ7CO9 RNAS1_HUMAN Increases Expression [104]
Ras-related protein Ral-B (RALB) OTFH203X RALB_HUMAN Decreases Expression [104]
Troponin I, cardiac muscle (TNNI3) OT65E12V TNNI3_HUMAN Increases Expression [104]
L-serine dehydratase/L-threonine deaminase (SDS) OT5WTJ2M SDHL_HUMAN Increases Expression [104]
DNA-directed RNA polymerase II subunit RPB1 (POLR2A) OTHJQ1DZ RPB1_HUMAN Increases Expression [104]
DNA excision repair protein ERCC-5 (ERCC5) OTQAKFJM ERCC5_HUMAN Increases Expression [104]
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) OTBDF9HJ ODO2_HUMAN Decreases Expression [104]
Protein phosphatase inhibitor 2 (PPP1R2) OTNLOUQR IPP2_HUMAN Decreases Expression [104]
Isoleucine--tRNA ligase, cytoplasmic (IARS1) OT9WXH5N SYIC_HUMAN Decreases Expression [104]
Transcription initiation factor TFIID subunit 6 (TAF6) OTY1Z9C4 TAF6_HUMAN Decreases Expression [104]
Protein Tob1 (TOB1) OTNW949D TOB1_HUMAN Decreases Expression [104]
Biotin--protein ligase (HLCS) OTPDUX30 BPL1_HUMAN Increases Expression [104]
Rho-related GTP-binding protein RhoN (RND2) OT98M6UI RND2_HUMAN Increases Expression [104]
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (NDST2) OT21PY3J NDST2_HUMAN Increases Expression [104]
Small ubiquitin-related modifier 3 (SUMO3) OTTUJQJ1 SUMO3_HUMAN Increases Expression [104]
Actin-related protein 3 (ACTR3) OT05LJSH ARP3_HUMAN Decreases Expression [104]
26S proteasome regulatory subunit 10B (PSMC6) OTG8997V PRS10_HUMAN Decreases Expression [104]
AP-2 complex subunit beta (AP2B1) OTL6LZJ4 AP2B1_HUMAN Decreases Expression [104]
Casein kinase II subunit alpha (CSNK2A1) OT9T8WQM CSK21_HUMAN Decreases Expression [104]
Pituitary homeobox 1 (PITX1) OTA0UN4C PITX1_HUMAN Increases Expression [104]
General transcription factor II-I (GTF2I) OTUYL1TQ GTF2I_HUMAN Decreases Expression [104]
Early growth response protein 4 (EGR4) OT4R3ECK EGR4_HUMAN Decreases Expression [104]
Voltage-dependent calcium channel gamma-1 subunit (CACNG1) OT6OCR3H CCG1_HUMAN Decreases Expression [104]
Sodium channel subunit beta-1 (SCN1B) OTGD78J3 SCN1B_HUMAN Increases Expression [104]
V-type proton ATPase 116 kDa subunit a 3 (TCIRG1) OTU1AIEW VPP3_HUMAN Increases Expression [104]
Phosphatidylinositol-binding clathrin assembly protein (PICALM) OTQVRPMQ PICAL_HUMAN Decreases Expression [104]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Decreases Expression [104]
TBC1 domain family member 10B (TBC1D10B) OT5MVCI5 TB10B_HUMAN Increases Expression [104]
Cyclin-J (CCNJ) OTCR4WVV CCNJ_HUMAN Increases Expression [104]
Tensin-3 (TNS3) OTPG2D8Z TENS3_HUMAN Increases Expression [104]
DENN domain-containing protein 5A (DENND5A) OT0QNNY1 DEN5A_HUMAN Increases Expression [104]
Kinesin-like protein KIF21A (KIF21A) OT511XD9 KI21A_HUMAN Increases Expression [104]
Calcium-activated potassium channel subunit beta-4 (KCNMB4) OTYQG46B KCMB4_HUMAN Decreases Expression [104]
EF-hand calcium-binding domain-containing protein 4A (CRACR2B) OT8L843R EFC4A_HUMAN Increases Expression [104]
Tumor protein p53-inducible protein 13 (TP53I13) OTSUH9V8 P5I13_HUMAN Increases Expression [104]
Basal body-orientation factor 1 (BBOF1) OT88DXU7 BBOF1_HUMAN Increases Expression [104]
Organic anion transporter 3 (SLC22A8) OT8BY933 S22A8_HUMAN Increases Expression [104]
Transient receptor potential cation channel subfamily M member 4 (TRPM4) OT354X8E TRPM4_HUMAN Increases Expression [104]
Protocadherin Fat 3 (FAT3) OT3C6H8W FAT3_HUMAN Increases Expression [104]
Sec1 family domain-containing protein 2 (SCFD2) OTYM55ET SCFD2_HUMAN Increases Expression [104]
Calcyphosin-like protein (CAPSL) OT5RRQ8E CAPSL_HUMAN Increases Expression [104]
Selenoprotein M (SELENOM) OTJ7PORS SELM_HUMAN Increases Expression [104]
Geranylgeranyl transferase type-2 subunit alpha (RABGGTA) OTYMG99C PGTA_HUMAN Increases Expression [104]
Ribonuclease K6 (RNASE6) OTJIK1RY RNAS6_HUMAN Increases Expression [104]
CAP-Gly domain-containing linker protein 3 (CLIP3) OTGJEGIB CLIP3_HUMAN Increases Expression [104]
Receptor expression-enhancing protein 6 (REEP6) OTY4FPO8 REEP6_HUMAN Increases Expression [104]
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) OTOE9OYV ACAP3_HUMAN Increases Expression [104]
Kinesin-like protein KIF20B (KIF20B) OTS68AHH KI20B_HUMAN Decreases Expression [104]
Translin-associated protein X (TSNAX) OTZ9SGWB TSNAX_HUMAN Increases Expression [104]
C-C motif chemokine 19 (CCL19) OTQ2UJMH CCL19_HUMAN Increases Expression [104]
Copine-1 (CPNE1) OTH5YKSL CPNE1_HUMAN Increases Expression [104]
Allograft inflammatory factor 1-like (AIF1L) OTDEOB80 AIF1L_HUMAN Increases Expression [104]
Bublin coiled-coil protein (BBLN) OTUMVEWE BBLN_HUMAN Increases Expression [104]
Transmembrane emp24 domain-containing protein 9 (TMED9) OTYGAQS0 TMED9_HUMAN Increases Expression [104]
Intraflagellar transport protein 27 homolog (IFT27) OT3NY6O6 IFT27_HUMAN Increases Expression [104]
E3 ubiquitin-protein ligase RNF26 (RNF26) OTPXA60S RNF26_HUMAN Increases Expression [104]
tRNA dimethylallyltransferase (TRIT1) OTCU9FS5 MOD5_HUMAN Increases Expression [104]
Striatin-4 (STRN4) OTHK2ZN6 STRN4_HUMAN Increases Expression [104]
Structural maintenance of chromosomes protein 4 (SMC4) OTEJE6AG SMC4_HUMAN Decreases Expression [104]
ATP-dependent RNA helicase DDX18 (DDX18) OTKB9C3S DDX18_HUMAN Decreases Expression [104]
Very long chain fatty acid elongase 5 (ELOVL5) OT375W1Z ELOV5_HUMAN Decreases Expression [104]
Programmed cell death 1 ligand 1 (CD274) OTJ0VFDL PD1L1_HUMAN Increases Expression [104]
Tropomodulin-4 (TMOD4) OTXLGJ4R TMOD4_HUMAN Increases Expression [104]
SUN domain-containing protein 2 (SUN2) OT2IQJUC SUN2_HUMAN Increases Expression [104]
Solute carrier family 22 member 6 (SLC22A6) OTKRCBVM S22A6_HUMAN Decreases Activity [125]
Organic anion transporter 7 (SLC22A9) OTO4BJCC S22A9_HUMAN Decreases Activity [125]
Solute carrier family 22 member 11 (SLC22A11) OTAJLNJZ S22AB_HUMAN Decreases Activity [125]
Mitogen-activated protein kinase 14 (MAPK14) OT5TCO3O MK14_HUMAN Increases Phosphorylation [134]
2'-5'-oligoadenylate synthase 1 (OAS1) OT8ZLOCY OAS1_HUMAN Increases Expression [129]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Expression [129]
Ezrin (EZR) OTHBPF1Z EZRI_HUMAN Decreases Expression [129]
Integrin beta-4 (ITGB4) OT28UK84 ITB4_HUMAN Decreases Expression [129]
Transcription factor JunD (JUND) OTNKACJD JUND_HUMAN Decreases Expression [129]
HLA class I histocompatibility antigen, alpha chain G (HLA-G) OTMLK1KN HLAG_HUMAN Decreases Expression [129]
G1/S-specific cyclin-D3 (CCND3) OTNKPQ22 CCND3_HUMAN Decreases Expression [129]
Leukocyte elastase inhibitor (SERPINB1) OT5RDUFO ILEU_HUMAN Decreases Expression [129]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [129]
Cell division control protein 42 homolog (CDC42) OT5QBC5M CDC42_HUMAN Decreases Expression [129]
Cyclin-dependent kinases regulatory subunit 1 (CKS1B) OTNUPLUJ CKS1_HUMAN Increases Expression [129]
Small ribosomal subunit protein uS9 (RPS16) OTVGZOB5 RS16_HUMAN Increases Expression [129]
Elongation factor 1-alpha 1 (EEF1A1) OT00THXS EF1A1_HUMAN Increases Expression [129]
Protein tyrosine phosphatase type IVA 1 (PTP4A1) OTK0NFXJ TP4A1_HUMAN Increases Expression [129]
Charged multivesicular body protein 1a (CHMP1A) OTVQ5UWX CHM1A_HUMAN Decreases Expression [129]
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) OTB3BFCV HNRDL_HUMAN Decreases Expression [105]
Nucleoside diphosphate kinase 6 (NME6) OTJNKOFA NDK6_HUMAN Increases Expression [105]
Alpha-1-antichymotrypsin (SERPINA3) OT9BP2S0 AACT_HUMAN Decreases Expression [105]
Cystatin-A (CSTA) OT1K68KE CYTA_HUMAN Increases Expression [105]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Decreases Expression [105]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Decreases Expression [105]
Beta-1,4-galactosyltransferase 1 (B4GALT1) OTBCXEK7 B4GT1_HUMAN Increases Expression [105]
Tyrosine-protein kinase Fer (FER) OT9JR7AE FER_HUMAN Decreases Expression [105]
Pulmonary surfactant-associated protein D (SFTPD) OTNKPDJC SFTPD_HUMAN Increases Expression [105]
Small ribosomal subunit protein eS19 (RPS19) OTBKGP48 RS19_HUMAN Increases Expression [105]
RNA-binding protein FXR2 (FXR2) OTQX7ATF FXR2_HUMAN Decreases Expression [105]
Ras-related protein Rab-2A (RAB2A) OT6SK83U RAB2A_HUMAN Increases Expression [105]
Hemoglobin subunit gamma-2 (HBG2) OT4J48JJ HBG2_HUMAN Increases Expression [105]
Butyrophilin subfamily 3 member A2 (BTN3A2) OT3DIBU3 BT3A2_HUMAN Decreases Expression [105]
Sushi repeat-containing protein SRPX (SRPX) OT5B9LXS SRPX_HUMAN Decreases Expression [105]
Metastasis-associated protein MTA1 (MTA1) OTBHW3S9 MTA1_HUMAN Increases Expression [105]
Ras GTPase-activating-like protein IQGAP2 (IQGAP2) OTX2UA7P IQGA2_HUMAN Increases Expression [105]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) OT6VY3A3 SPTN1_HUMAN Decreases Expression [105]
MOB kinase activator 2 (MOB2) OTMBE0NS MOB2_HUMAN Increases Expression [105]
Centromere protein S (CENPS) OTZ4J391 CENPS_HUMAN Increases Expression [105]
LIM domain only protein 7 (LMO7) OTDLY6TC LMO7_HUMAN Increases Expression [105]
Neuronal cell adhesion molecule (NRCAM) OT80HHQ2 NRCAM_HUMAN Decreases Expression [105]
N-alpha-acetyltransferase 38, NatC auxiliary subunit (NAA38) OTI8VWK3 LSMD1_HUMAN Increases Expression [105]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Decreases Expression [105]
Translocon-associated protein subunit gamma (SSR3) OTJQP0IZ SSRG_HUMAN Increases Expression [105]
Cytosolic Fe-S cluster assembly factor NUBP2 (NUBP2) OTYOTM2B NUBP2_HUMAN Decreases Expression [105]
Pseudouridylate synthase 1 homolog (PUS1) OTS2DQ0N PUS1_HUMAN Increases Expression [105]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) OTWICA51 PSD12_HUMAN Increases Expression [106]
Importin subunit alpha-4 (KPNA3) OTLI3TM2 IMA4_HUMAN Increases Expression [106]
Chromodomain-helicase-DNA-binding protein 2 (CHD2) OTRKL6YC CHD2_HUMAN Increases Expression [106]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Increases Expression [106]
E3 ubiquitin-protein ligase SIAH2 (SIAH2) OTKED2XN SIAH2_HUMAN Decreases Expression [106]
Tumor protein D54 (TPD52L2) OTTOG0NK TPD54_HUMAN Decreases Expression [106]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) OTJKOMXE BNI3L_HUMAN Increases Expression [106]
GDNF family receptor alpha-3 (GFRA3) OT07XAZF GFRA3_HUMAN Increases Expression [106]
Tetraspanin-3 (TSPAN3) OT7WS6ZI TSN3_HUMAN Decreases Expression [106]
Breast cancer anti-estrogen resistance protein 3 (BCAR3) OTPJ17M8 BCAR3_HUMAN Increases Expression [106]
PRA1 family protein 3 (ARL6IP5) OTYZ6BEQ PRAF3_HUMAN Increases Expression [106]
Gamma-aminobutyric acid receptor-associated protein (GABARAP) OTAQUX6E GBRAP_HUMAN Decreases Expression [106]
Histone acetyltransferase KAT7 (KAT7) OTUN98IC KAT7_HUMAN Decreases Expression [106]
STAM-binding protein (STAMBP) OTOT2OXM STABP_HUMAN Increases Expression [106]
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) OTBMJUOC M4K4_HUMAN Decreases Expression [106]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Decreases Expression [106]
T-cell surface glycoprotein CD8 alpha chain (CD8A) OTDWQJXK CD8A_HUMAN Decreases Expression [106]
Antileukoproteinase (SLPI) OTUNFUU8 SLPI_HUMAN Decreases Expression [106]
Fructose-bisphosphate aldolase A (ALDOA) OTWRFTIB ALDOA_HUMAN Decreases Expression [106]
HLA class II histocompatibility antigen gamma chain (CD74) OTO16X4Q HG2A_HUMAN Decreases Expression [106]
Argininosuccinate lyase (ASL) OTI2NGQR ARLY_HUMAN Decreases Expression [106]
Calpain small subunit 1 (CAPNS1) OT95EBBD CPNS1_HUMAN Decreases Expression [106]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) OTEG4KU9 RPN1_HUMAN Decreases Expression [106]
Tyrosine-protein kinase Lck (LCK) OT883FG9 LCK_HUMAN Decreases Expression [106]
Profilin-1 (PFN1) OTHTGA1H PROF1_HUMAN Decreases Expression [106]
Tyrosine-protein kinase Lyn (LYN) OTP686K2 LYN_HUMAN Increases Expression [106]
Tyrosine-protein kinase HCK (HCK) OTRL6OSI HCK_HUMAN Decreases Expression [106]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [106]
Cation-independent mannose-6-phosphate receptor (IGF2R) OTDXPQVX MPRI_HUMAN Increases Expression [106]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) OT9DERT1 GILT_HUMAN Decreases Expression [106]
Hematopoietic lineage cell-specific protein (HCLS1) OTX7WGYN HCLS1_HUMAN Decreases Expression [106]
Interleukin-2 receptor subunit beta (IL2RB) OT6M0F70 IL2RB_HUMAN Increases Expression [106]
Metalloproteinase inhibitor 2 (TIMP2) OT8S1RRP TIMP2_HUMAN Decreases Expression [106]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Increases Expression [106]
Calpain-2 catalytic subunit (CAPN2) OTIAPE5J CAN2_HUMAN Increases Expression [106]
Probable ATP-dependent RNA helicase DDX5 (DDX5) OTLS124U DDX5_HUMAN Increases Expression [106]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Decreases Expression [106]
E3 ubiquitin-protein ligase TRIM21 (TRIM21) OTA4UJCF RO52_HUMAN Decreases Expression [106]
Transcription factor E3 (TFE3) OTM99ZWH TFE3_HUMAN Decreases Expression [106]
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) OTXF0B09 IF2B_HUMAN Increases Expression [106]
Interferon-induced GTP-binding protein Mx1 (MX1) OT6X8G5T MX1_HUMAN Decreases Expression [106]
fMet-Leu-Phe receptor (FPR1) OTFF9I6W FPR1_HUMAN Decreases Expression [106]
Granulysin (GNLY) OTZJKA8C GNLY_HUMAN Decreases Expression [106]
Peptidyl-prolyl cis-trans isomerase B (PPIB) OTLPH6KN PPIB_HUMAN Decreases Expression [106]
Calnexin (CANX) OTYP1F6J CALX_HUMAN Decreases Expression [106]
High affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) OTBZBL9Y FCERG_HUMAN Decreases Expression [106]
Syndecan-4 (SDC4) OTKUVUGZ SDC4_HUMAN Decreases Expression [106]
Cytokine receptor common subunit gamma (IL2RG) OTRZ3OMY IL2RG_HUMAN Decreases Expression [106]
Protein S100-A11 (S100A11) OTI57KDN S10AB_HUMAN Decreases Expression [106]
Intercellular adhesion molecule 3 (ICAM3) OTTZ5A5D ICAM3_HUMAN Decreases Expression [106]
Protein EVI2B (EVI2B) OT98X1OE EVI2B_HUMAN Increases Expression [106]
Protein DEK (DEK) OTYCJ5H6 DEK_HUMAN Increases Expression [106]
F-actin-capping protein subunit alpha-2 (CAPZA2) OTHAO4V2 CAZA2_HUMAN Increases Expression [106]
Paxillin (PXN) OTVMMUOF PAXI_HUMAN Decreases Expression [106]
Large ribosomal subunit protein eL34 (RPL34) OT0U9VMQ RL34_HUMAN Increases Expression [106]
Dual specificity protein kinase CLK2 (CLK2) OT1CRSY2 CLK2_HUMAN Decreases Expression [106]
Dual specificity protein kinase CLK3 (CLK3) OT74DJ3J CLK3_HUMAN Decreases Expression [106]
Death-associated protein 1 (DAP) OT5YLL7E DAP1_HUMAN Decreases Expression [106]
Signal transducer and activator of transcription 5B (STAT5B) OTZVPEBT STA5B_HUMAN Decreases Expression [106]
F-actin-capping protein subunit alpha-1 (CAPZA1) OTAXA66U CAZA1_HUMAN Increases Expression [106]
Protein FosB (FOSB) OTW6C05J FOSB_HUMAN Decreases Expression [106]
Protein SEC13 homolog (SEC13) OTSR4WWM SEC13_HUMAN Decreases Expression [106]
cAMP-regulated phosphoprotein 19 (ARPP19) OTZS3IT6 ARP19_HUMAN Increases Expression [106]
ATP synthase subunit epsilon, mitochondrial (ATP5F1E) OTMPLAIS ATP5E_HUMAN Increases Expression [106]
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) OT4B0TNV PP4C_HUMAN Decreases Expression [106]
V-type proton ATPase subunit d 1 (ATP6V0D1) OT9GU2NW VA0D1_HUMAN Decreases Expression [106]
Protein BTG1 (BTG1) OTVJ2CDM BTG1_HUMAN Increases Expression [106]
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) OT3JPRCQ GBB2_HUMAN Decreases Expression [106]
Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) OTIIGGZ2 RS27A_HUMAN Increases Expression [106]
Transformer-2 protein homolog beta (TRA2B) OTZYQW52 TRA2B_HUMAN Increases Expression [106]
Rho-related GTP-binding protein RhoG (RHOG) OTJ7J1WA RHOG_HUMAN Decreases Expression [106]
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) OTLQN1E2 HNRPU_HUMAN Increases Expression [106]
Interferon regulatory factor 9 (IRF9) OTK4MYQJ IRF9_HUMAN Decreases Expression [106]
Collagen alpha-1(VII) chain (COL7A1) OT3MIRZJ CO7A1_HUMAN Decreases Expression [106]
Killer cell lectin-like receptor subfamily B member 1 (KLRB1) OTQ2959Y KLRB1_HUMAN Increases Expression [106]
Protein flightless-1 homolog (FLII) OT7G9JG6 FLII_HUMAN Decreases Expression [106]
Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5) OT6T408U MP2K5_HUMAN Decreases Expression [106]
Peptidyl-prolyl cis-trans isomerase G (PPIG) OTZ8BTTM PPIG_HUMAN Increases Expression [106]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Increases Expression [106]
Flotillin-2 (FLOT2) OTZ0QR5L FLOT2_HUMAN Decreases Expression [106]
Protein tyrosine phosphatase receptor type C-associated protein (PTPRCAP) OT2YERNV PTCA_HUMAN Decreases Expression [106]
Poly(rC)-binding protein 1 (PCBP1) OTHN0TD7 PCBP1_HUMAN Decreases Expression [106]
Homeobox protein TGIF1 (TGIF1) OTN9VHAG TGIF1_HUMAN Decreases Expression [106]
Myeloid leukemia factor 2 (MLF2) OTU3B4WU MLF2_HUMAN Decreases Expression [106]
Protein NKG7 (NKG7) OTXDD006 NKG7_HUMAN Decreases Expression [106]
Guanylate kinase (GUK1) OTLI0HRU KGUA_HUMAN Decreases Expression [106]
All-trans retinoic acid-induced differentiation factor (ATRAID) OTOHZG1O ARAID_HUMAN Decreases Expression [106]
eIF5-mimic protein 2 (BZW1) OT4GUFIG 5MP2_HUMAN Increases Expression [106]
F-box only protein 11 (FBXO11) OTGWF3Q2 FBX11_HUMAN Increases Expression [106]
Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2) OT1O2K47 LIRA2_HUMAN Decreases Expression [106]
Protein odd-skipped-related 1 (OSR1) OTB19LEQ OSR1_HUMAN Increases Expression [106]
Pumilio homolog 2 (PUM2) OT2H7NXV PUM2_HUMAN Increases Expression [106]
PEST proteolytic signal-containing nuclear protein (PCNP) OTJUQ122 PCNP_HUMAN Increases Expression [106]
MAP kinase-activating death domain protein (MADD) OTUFYVGG MADD_HUMAN Decreases Expression [106]
Nuclear receptor subfamily 4 group A member 3 (NR4A3) OTPBE9R1 NR4A3_HUMAN Increases Expression [106]
Protein TFG (TFG) OT2KJENI TFG_HUMAN Increases Expression [106]
Ninjurin-1 (NINJ1) OTLRZ1EU NINJ1_HUMAN Decreases Expression [106]
Erbin (ERBIN) OTNWTUA8 ERBIN_HUMAN Increases Expression [106]
V-type proton ATPase 21 kDa proteolipid subunit c'' (ATP6V0B) OT8GTI1V VATO_HUMAN Decreases Expression [106]
ETS-related transcription factor Elf-4 (ELF4) OT167PR5 ELF4_HUMAN Decreases Expression [106]
Prohibitin-2 (PHB2) OTCAX3AW PHB2_HUMAN Decreases Expression [106]
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) OTJP4U7K HNRL1_HUMAN Decreases Expression [106]
Programmed cell death protein 10 (PDCD10) OTCHJTSF PDC10_HUMAN Increases Expression [106]
GTP-binding protein 2 (GTPBP2) OTOJ1KUA GTPB2_HUMAN Decreases Expression [106]
NF-kappa-B inhibitor zeta (NFKBIZ) OTU728KS IKBZ_HUMAN Increases Expression [106]
Large ribosomal subunit protein mL46 (MRPL46) OTMQ2A0Q RM46_HUMAN Increases Expression [106]
Growth hormone-inducible transmembrane protein (GHITM) OTBPNIC0 GHITM_HUMAN Increases Expression [106]
E3 ubiquitin-protein ligase SMURF2 (SMURF2) OT3TRVL7 SMUF2_HUMAN Increases Expression [106]
Mediator of RNA polymerase II transcription subunit 4 (MED4) OTALFN4S MED4_HUMAN Increases Expression [106]
PDZ and LIM domain protein 7 (PDLIM7) OTAZVODU PDLI7_HUMAN Decreases Expression [106]
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG1) OTFOJUIQ PHAG1_HUMAN Increases Expression [106]
Peflin (PEF1) OTY24CUW PEF1_HUMAN Decreases Expression [106]
Tyrosine-protein kinase BAZ1B (BAZ1B) OTD5KR2J BAZ1B_HUMAN Decreases Expression [106]
F-box/LRR-repeat protein 3 (FBXL3) OTDQ1QKV FBXL3_HUMAN Increases Expression [106]
Apoptotic chromatin condensation inducer in the nucleus (ACIN1) OTK81F92 ACINU_HUMAN Decreases Expression [106]
Transforming acidic coiled-coil-containing protein 3 (TACC3) OTRNEZTA TACC3_HUMAN Decreases Expression [106]
Diamine acetyltransferase 1 (SAT1) OT52AU22 SAT1_HUMAN Increases Expression [135]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Decreases Activity [136]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Decreases Activity [136]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Decreases Activity [136]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Increases Expression [137]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [137]
Proepiregulin (EREG) OTRM4NQY EREG_HUMAN Increases Expression [138]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [139]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Increases Expression [126]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Increases Expression [126]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Increases Expression [137]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Expression [140]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Decreases Expression [141]
Serine/threonine-protein kinase Chk2 (CHEK2) OT8ZPCNS CHK2_HUMAN Increases Expression [137]
Ornithine transcarbamylase, mitochondrial (OTC) OTJ57GGA OTC_HUMAN Decreases Expression [142]
Prothrombin (F2) OTNFSM49 THRB_HUMAN Affects Cleavage [143]
Renin (REN) OT52GZR2 RENI_HUMAN Decreases Activity [144]
Metalloproteinase inhibitor 1 (TIMP1) OTOXC51H TIMP1_HUMAN Increases Expression [145]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Decreases Expression [137]
Fibrinogen alpha chain (FGA) OTMIHY80 FIBA_HUMAN Decreases Secretion [146]
Fibrinogen beta chain (FGB) OT6RKLI9 FIBB_HUMAN Decreases Secretion [146]
Albumin (ALB) OTVMM513 ALBU_HUMAN Decreases Secretion [146]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Expression [137]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Decreases Expression [147]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Decreases Expression [148]
Calpain-1 catalytic subunit (CAPN1) OTK6OQZR CAN1_HUMAN Increases Expression [149]
Tumor necrosis factor receptor superfamily member 16 (NGFR) OTPKSM49 TNR16_HUMAN Increases Expression [150]
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Increases Expression [138]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [151]
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) OTA4P0FC ACADM_HUMAN Increases Expression [152]
Granzyme A (GZMA) OT43R33L GRAA_HUMAN Decreases Expression [137]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Affects Methylation [153]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Decreases Expression [154]
Transcription factor 4 (TCF4) OTB9ASTK ITF2_HUMAN Decreases Activity [155]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Decreases Expression [156]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Decreases Expression [157]
Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) OT2D9DOV TNR1A_HUMAN Increases Expression [137]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [107]
N-formyl peptide receptor 2 (FPR2) OTEZ2THZ FPR2_HUMAN Increases Expression [158]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Increases Expression [137]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Decreases Expression [137]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Expression [159]
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) OT5BZ1J9 P85A_HUMAN Decreases Expression [137]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Expression [159]
CD40 ligand (CD40LG) OT75Z6A6 CD40L_HUMAN Decreases Expression [160]
M-phase inducer phosphatase 1 (CDC25A) OTSLKKCO MPIP1_HUMAN Decreases Expression [137]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Decreases Localization [156]
Serpin B5 (SERPINB5) OTSMXQRJ SPB5_HUMAN Increases Expression [161]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Decreases Expression [137]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Decreases Expression [137]
Interleukin-6 receptor subunit beta (IL6ST) OT1N9C70 IL6RB_HUMAN Decreases Expression [110]
CD151 antigen (CD151) OTF3UZS7 CD151_HUMAN Decreases Expression [130]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) OTI862QH CPT1A_HUMAN Increases Expression [152]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Response To Substance [162]
Mitogen-activated protein kinase 12 (MAPK12) OTTCKE27 MK12_HUMAN Decreases Expression [107]
Microsomal triglyceride transfer protein large subunit (MTTP) OTNUVSDT MTP_HUMAN Decreases Expression [163]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Increases Cleavage [164]
Small ribosomal subunit protein eS6 (RPS6) OTT4D1LN RS6_HUMAN Decreases Phosphorylation [157]
Dermcidin (DCD) OTV5PBGJ DCD_HUMAN Decreases Secretion [146]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) OT1SLUZH TSG6_HUMAN Decreases Expression [138]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Increases Activity [165]
Transcription factor E2F1 (E2F1) OTLKYBBC E2F1_HUMAN Decreases Expression [137]
Cytochrome P450 4A11 (CYP4A11) OTPU5J0S CP4AB_HUMAN Affects Activity [166]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Increases Localization [167]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Increases Expression [168]
Peroxisomal bifunctional enzyme (EHHADH) OTBAAHL5 ECHP_HUMAN Decreases Expression [163]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Increases Expression [152]
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) OT7TNF0L AAPK1_HUMAN Increases Expression [152]
Serine-protein kinase ATM (ATM) OTQVOHLT ATM_HUMAN Increases Expression [137]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [169]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Decreases Expression [137]
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) OTVZ7I3A TNR25_HUMAN Increases Expression [137]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Increases Expression [140]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [140]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Decreases Expression [164]
Gastrokine-1 (GKN1) OT7ZYFQ9 GKN1_HUMAN Affects Expression [170]
Mammalian ependymin-related protein 1 (EPDR1) OT5JW5RB EPDR1_HUMAN Decreases Expression [137]
Cysteinyl leukotriene receptor 1 (CYSLTR1) OT904HBN CLTR1_HUMAN Increases Expression [171]
Kinesin-like protein KIF3A (KIF3A) OTMUBSSK KIF3A_HUMAN Increases Expression [172]
Voltage-dependent calcium channel gamma-6 subunit (CACNG6) OT2PC1E1 CCG6_HUMAN Affects Response To Substance [173]
Platelet glycoprotein Ib alpha chain (GP1BA) OT62PSOB GP1BA_HUMAN Increases Response To Substance [174]
Pikachurin (EGFLAM) OTACZZJ0 EGFLA_HUMAN Increases ADR [133]
Regulator of G-protein signaling 7-binding protein (RGS7BP) OTAGSWMH R7BP_HUMAN Affects Response To Substance [175]
Serine/threonine-protein kinase 10 (STK10) OTC33Y2F STK10_HUMAN Affects Response To Substance [176]
Cocaine esterase (CES2) OTC647SQ EST2_HUMAN Increases Hydrolysis [177]
Solute carrier family 22 member 2 (SLC22A2) OTGFK1AL S22A2_HUMAN Affects Response To Substance [178]
Bis(5'-adenosyl)-triphosphatase (FHIT) OTGWBSLA FHIT_HUMAN Increases ADR [133]
Adenosine receptor A3 (ADORA3) OTHO1BLK AA3R_HUMAN Affects Response To Substance [179]
Adenosine receptor A1 (ADORA1) OTI7X39E AA1R_HUMAN Affects Response To Substance [180]
Leucine-rich melanocyte differentiation-associated protein (LRMDA) OTIPNKTU LRMDA_HUMAN Increases ADR [128]
High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) OTIRUOHF FCERA_HUMAN Affects Response To Substance [181]
Sodium- and chloride-dependent betaine transporter (SLC6A12) OTKOR4F2 S6A12_HUMAN Affects Response To Substance [182]
High affinity immunoglobulin epsilon receptor subunit beta (MS4A2) OTMCAS2D FCERB_HUMAN Affects Response To Substance [183]
Stromal membrane-associated protein 2 (SMAP2) OTPGVRKO SMAP2_HUMAN Affects Response To Substance [184]
Growth arrest-specific protein 6 (GAS6) OTPOPUUE GAS6_HUMAN Affects Response To Substance [185]
Prostaglandin E synthase 3 (PTGES3) OTPPQWI0 TEBP_HUMAN Increases ADR [24]
Inosine triphosphate pyrophosphatase (ITPA) OTQ47WVR ITPA_HUMAN Increases ADR [186]
Cysteinyl leukotriene receptor 2 (CYSLTR2) OTRNEOZ0 CLTR2_HUMAN Affects Response To Substance [181]
Disintegrin and metalloproteinase domain-containing protein 33 (ADAM33) OTRZVI77 ADA33_HUMAN Affects Response To Substance [187]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Affects Response To Substance [188]
Adenosine receptor A2a (ADORA2A) OTVRBZ0I AA2AR_HUMAN Affects Response To Substance [180]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Increases ADR [189]
Antigen peptide transporter 2 (TAP2) OTWSYFI7 TAP2_HUMAN Affects Response To Substance [190]
Fibrous sheath-interacting protein 1 (FSIP1) OTYLL6GM FSIP1_HUMAN Affects Response To Substance [191]
Galectin-10 (CLC) OTYMYR85 LEG10_HUMAN Affects Response To Substance [192]
Centrosomal protein of 68 kDa (CEP68) OTZDM4J1 CEP68_HUMAN Affects Response To Substance [193]
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) OTZM6MHU NLRP3_HUMAN Affects Response To Substance [194]
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References

1 ClinicalTrials.gov (NCT00719537) Oral Progesterone and Low Dose Aspirin in the Prevention of Preeclampsia
2 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 075906.
3 Progesterone FDA Label
4 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2377).
5 ClinicalTrials.gov (NCT00822900) Progesterone for the Treatment of Traumatic Brain Injury III. U.S. National Institutes of Health.
6 ClinicalTrials.gov (NCT04365127) Progesterone for the Treatment of COVID-19 in Hospitalized Men. U.S. National Institutes of Health.
7 Aspirin FDA Label
8 Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
9 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4139).
10 Protective Effect of Aspirin on COVID-19 Patients (PEAC)
11 Progesterone regulation of implantation-related genes: new insights into the role of oestrogen. Cell Mol Life Sci. 2007 Apr;64(7-8):1009-32.
12 Gene expression in endometrial cancer cells (Ishikawa) after short time high dose exposure to progesterone. Steroids. 2008 Jan;73(1):116-28.
13 Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. BMC Cancer. 2007 Dec 11;7:223.
14 Progestins regulate genes that can elicit both proliferative and antiproliferative effects in breast cancer cells. Oncol Rep. 2008 Jun;19(6):1627-34.
15 Effect of ovarian steroids on gene expression profile in human uterine microvascular endothelial cells. Fertil Steril. 2009 Aug;92(2):709-21.
16 Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. Biol Reprod. 2011 Apr;84(4):801-15.
17 Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis. Hum Reprod. 2011 Jul;26(7):1813-25.
18 Effects of progesterone treatment on expression of genes involved in uterine quiescence. Reprod Sci. 2011 Aug;18(8):781-97.
19 The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill. J Renin Angiotensin Aldosterone Syst. 2008 Dec;9(4):221-5. doi: 10.1177/1470320308096405.
20 Perfluorooctanoic acid alters progesterone activity in human endometrial cells and induces reproductive alterations in young women. Chemosphere. 2020 Mar;242:125208. doi: 10.1016/j.chemosphere.2019.125208. Epub 2019 Oct 24.
21 Expression of estrogen-, progesterone-, and androgen-responsive genes in MCF-7 and MDA-MB-231 cells treated with o,p'-DDT, p,p'-DDT, or endosulfan. J Biochem Mol Toxicol. 2021 Jun;35(6):1-8. doi: 10.1002/jbt.22773. Epub 2021 Mar 16.
22 Progesterone up-regulates WT1 mRNA and protein, and alters the relative expression of WT1 transcripts in cultured endometrial stromal cells. J Soc Gynecol Investig. 2003 Dec;10(8):509-16. doi: 10.1016/s1071-5576(03)00147-3.
23 Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. Environ Health Perspect. 2015 May;123(5):458-66. doi: 10.1289/ehp.1408775. Epub 2015 Jan 13.
24 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
25 Luteinizing hormone-stimulated pituitary adenylate cyclase-activating polypeptide system and its role in progesterone production in human luteinized granulosa cells. Endocr J. 2010;57(2):127-34. doi: 10.1507/endocrj.k09e-077. Epub 2009 Nov 19.
26 Clinical pipeline report, company report or official report of lipocine.
27 Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharm Res. 2001 Dec;18(12):1660-8.
28 Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. J Biol Chem. 2003 Jun 6;278(23):20645-51.
29 Contribution of human hepatic cytochrome P450 isoforms to regioselective hydroxylation of steroid hormones. Xenobiotica. 1998 Jun;28(6):539-47.
30 Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.
31 Allelic variants of human cytochrome P450 1A1 (CYP1A1): effect of T461N and I462V substitutions on steroid hydroxylase specificity. Pharmacogenetics. 2000 Aug;10(6):519-30.
32 Progestagenic effects of tibolone are target gene-specific in human endometrial cells. J Soc Gynecol Investig. 2006 Sep;13(6):459-65.
33 Effect of genetic polymorphism on the metabolism of endogenous neuroactive substances, progesterone and p-tyramine, catalyzed by CYP2D6. Brain Res Mol Brain Res. 2004 Oct 22;129(1-2):117-23.
34 Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s. Arch Biochem Biophys. 1991 Oct;290(1):160-6.
35 Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones. J Biol Chem. 2001 Aug 31;276(35):33061-5.
36 Human prostate CYP3A5: identification of a unique 5'-untranslated sequence and characterization of purified recombinant protein. Biochem Biophys Res Commun. 1999 Jul 14;260(3):676-81.
37 The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver. J Steroid Biochem Mol Biol. 1993 Jan;44(1):61-7.
38 Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes. Arch Biochem Biophys. 1997 Oct 1;346(1):161-9.
39 Catalytic properties of polymorphic human cytochrome P450 1B1 variants. Carcinogenesis. 1999 Aug;20(8):1607-13.
40 Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain. Biochemistry. 2003 Dec 9;42(48):14284-92.
41 Human cytochrome P450 21A2, the major steroid 21-hydroxylase: structure of the enzyme progesterone substrate complex and rate-limiting C-H bond cleavage. J Biol Chem. 2015 May 22;290(21):13128-43.
42 Human 3-alpha hydroxysteroid dehydrogenase type 3 (3alpha-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20alpha-HSD activity. J Steroid Biochem Mol Biol. 2014 May;141:135-43.
43 Engineering of CYP106A2 for steroid 9alpha- and 6beta-hydroxylation. Steroids. 2017 Apr;120:41-48.
44 acillus megaterium SF185 spores exert protective effects against oxidative stress in vivo and in vitro. Sci Rep. 2019 Aug 19;9(1):12082.
45 Progestin effects on expression of AKR1C1-AKR1C3, SRD5A1 and PGR in the Z-12 endometriotic epithelial cell line. Chem Biol Interact. 2013 Feb 25;202(1-3):218-25.
46 Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2009 Jan;94(1):89-95. doi: 10.1210/jc.2008-1174. Epub 2008 Oct 28.
47 Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. Cell Tissue Res. 2012 Aug;349(2):551-63. doi: 10.1007/s00441-012-1417-5. Epub 2012 May 13.
48 P-glycoprotein (P-gp/MDR1)-mediated efflux of sex-steroid hormones and modulation of P-gp expression in vitro. Pharm Res. 2004 Jul;21(7):1284-93.
49 Progesterone increases csk homologous kinase in HMC-1560 human mast cells and reduces cell proliferation. J Cell Biochem. 2007 Dec 1;102(5):1271-80. doi: 10.1002/jcb.21357.
50 Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter. Endocr Relat Cancer. 2009 Jun;16(2):549-64. doi: 10.1677/ERC-08-0232. Epub 2009 Mar 4.
51 Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3. Br J Pharmacol. 2002 Jul;136(6):829-36.
52 The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion. Mol Endocrinol. 2005 May;19(5):1170-80.
53 Further insights into the regulation of human FAAH by progesterone and leptin implications for endogenous levels of anandamide and apoptosis of immune and neuronal cells. Neurotoxicology. 2005 Oct;26(5):811-7.
54 Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). Toxicol Sci. 2013 Dec;136(2):328-43.
55 Influence of the estrous cycle on clock gene expression in reproductive tissues: effects of fluctuating ovarian steroid hormone levels. Steroids. 2010 Mar;75(3):203-12. doi: 10.1016/j.steroids.2010.01.007. Epub 2010 Jan 22.
56 HOXA10 regulates endometrial GABAA {pi} receptor expression and membrane translocation. Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E889-93. doi: 10.1152/ajpendo.00577.2009. Epub 2010 Jan 26.
57 Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into Th17 cells. J Immunol. 2011 Aug 15;187(4):1778-87. doi: 10.4049/jimmunol.1003919. Epub 2011 Jul 18.
58 Modulation of human beta-defensin-2 expression by 17beta-estradiol and progesterone in vaginal epithelial cells. Cytokine. 2010 Feb;49(2):209-14. doi: 10.1016/j.cyto.2009.09.005. Epub 2009 Oct 9.
59 Expression and modulation of progesterone induced blocking factor (PIBF) and innate immune factors in human leukemia cell lines by progesterone and mifepristone. Leuk Lymphoma. 2007 Aug;48(8):1610-7. doi: 10.1080/10428190701471999.
60 Triclosan and bisphenol a affect decidualization of human endometrial stromal cells. Mol Cell Endocrinol. 2016 Feb 15;422:74-83. doi: 10.1016/j.mce.2015.11.017. Epub 2015 Nov 19.
61 Progesterone rise on HCG day in GnRH antagonist/rFSH stimulated cycles affects endometrial gene expression. Reprod Biomed Online. 2011 Mar;22(3):263-71. doi: 10.1016/j.rbmo.2010.11.002. Epub 2010 Nov 13.
62 High levels of caveolar cholesterol inhibit progesterone-induced genomic actions in human and guinea pig gallbladder muscle. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G948-54. doi: 10.1152/ajpgi.90699.2008. Epub 2009 Feb 12.
63 Progestin regulates chemokine (C-X-C motif) ligand 14 transcript level in human endometrium. Mol Hum Reprod. 2010 Mar;16(3):170-7. doi: 10.1093/molehr/gap100. Epub 2009 Nov 10.
64 Thrombotic predisposition associated with oral contraceptives. Obstet Gynecol. 1973 Mar;41(3):427-35.
65 The impact of luteal phase support on gene expression of extracellular matrix protein and adhesion molecules in the human endometrium during the window of implantation following controlled ovarian stimulation with a GnRH antagonist protocol. Fertil Steril. 2010 Nov;94(6):2264-71. doi: 10.1016/j.fertnstert.2010.01.068. Epub 2010 Mar 12.
66 Progesterone and 17beta-estradiol enhance regulatory responses to human papillomavirus type 16 virus-like particles in peripheral blood mononuclear cells from healthy women. Clin Vaccine Immunol. 2010 Apr;17(4):609-17. doi: 10.1128/CVI.00441-09. Epub 2010 Feb 3.
67 Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and -fetoprotein. Toxicol Sci. 2015 Feb;143(2):333-48. doi: 10.1093/toxsci/kfu231. Epub 2014 Oct 27.
68 Glucocorticoid regulation of human pulmonary surfactant protein-B (SP-B) mRNA stability is independent of activated glucocorticoid receptor. Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L940-50. doi: 10.1152/ajplung.00420.2010. Epub 2011 Mar 11.
69 Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fertil Steril. 2005 Jul;84(1):67-74. doi: 10.1016/j.fertnstert.2005.01.113.
70 Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and CXCL2 in ovarian and endometrial cancer cells. J Cell Biochem. 2012 Oct;113(10):3143-52. doi: 10.1002/jcb.24191.
71 A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor in an MCF-7 Microarray Compendium. Chem Res Toxicol. 2021 Feb 15;34(2):313-329. doi: 10.1021/acs.chemrestox.0c00243. Epub 2021 Jan 6.
72 Differential regulation of glucose transporter expression by estrogen and progesterone in Ishikawa endometrial cancer cells. J Endocrinol. 2004 Sep;182(3):467-78. doi: 10.1677/joe.0.1820467.
73 [Mifepristone inhibits the progesterone-induced expressions of HLA-G, -E, -F genes in trophoblasts during first trimester]. Zhonghua Yi Xue Za Zhi. 2012 Jan 3;92(1):15-7.
74 Progesterone induction of chondroitin sulfate proteoglycan aggrecan expression in human endometrial epithelial cells. J Steroid Biochem Mol Biol. 2010 Oct;122(4):159-63. doi: 10.1016/j.jsbmb.2010.07.004. Epub 2010 Jul 29.
75 Progesterone enhances HLA-G gene expression in JEG-3 choriocarcinoma cells and human cytotrophoblasts in vitro. Hum Reprod. 2006 Jan;21(1):46-51. doi: 10.1093/humrep/dei305. Epub 2005 Oct 6.
76 Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling. Oncogene. 2005 Mar 3;24(10):1774-87. doi: 10.1038/sj.onc.1207991.
77 Differential effects of estrogen and progesterone on potassium channels expressed in Xenopus oocytes. Steroids. 2008 Mar;73(3):272-9. doi: 10.1016/j.steroids.2007.10.010. Epub 2007 Nov 4.
78 Progesterone induces the fibulin-1 expression in human endometrial stromal cells. Hum Reprod. 2005 Jun;20(6):1447-55. doi: 10.1093/humrep/deh841. Epub 2005 Mar 17.
79 Gonadal steroids regulate GABAA receptor subunit mRNA expression in NT2-N neurons. Brain Res Mol Brain Res. 2005 Aug 18;138(2):105-15. doi: 10.1016/j.molbrainres.2004.10.047.
80 The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer. PLoS One. 2012;7(10):e46985. doi: 10.1371/journal.pone.0046985. Epub 2012 Oct 10.
81 Progesterone inhibits human endothelial cell proliferation through a p53-dependent pathway. Cell Mol Life Sci. 2008 Nov;65(23):3839-50. doi: 10.1007/s00018-008-8441-3.
82 Progesterone pre-treatment potentiates EGF pathway signaling in the breast cancer cell line ZR-75. Breast Cancer Res Treat. 2005 Nov;94(2):171-83. doi: 10.1007/s10549-005-7726-6.
83 Elucidating progesterone effects in breast cancer: cross talk with PDGF signaling pathway in smooth muscle cell. J Cell Biochem. 2007 Jan 1;100(1):174-83. doi: 10.1002/jcb.21045.
84 Ovarian steroids, mitogen-activated protein kinases, and/or aspartic proteinases cooperate to control endometrial remodeling by regulating gene expression in the stroma and glands. Endocrinology. 2010 Sep;151(9):4515-26. doi: 10.1210/en.2009-1398. Epub 2010 Jul 21.
85 Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F. Mol Cancer Res. 2011 Nov;9(11):1479-92. doi: 10.1158/1541-7786.MCR-11-0213. Epub 2011 Sep 20.
86 The human myometrium differentially expresses mTOR signalling components before and during pregnancy: evidence for regulation by progesterone. J Steroid Biochem Mol Biol. 2014 Jan;139:166-72. doi: 10.1016/j.jsbmb.2013.02.017. Epub 2013 Mar 26.
87 Conditional regulation of the human CYP4X1 and CYP4Z1 genes. Arch Biochem Biophys. 2005 Apr 15;436(2):377-85. doi: 10.1016/j.abb.2005.02.022.
88 Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E57-61. doi: 10.1152/ajpendo.00696.2006. Epub 2007 Mar 6.
89 Bisphenol A prevents MCF-7 breast cell apoptosis via the inhibition of progesterone receptor transactivation. J Biochem Mol Toxicol. 2023 Jul;37(7):e23367. doi: 10.1002/jbt.23367. Epub 2023 Apr 3.
90 Adiponectin Reverses the Proliferative Effects of Estradiol and IGF-1 in Human Epithelial Ovarian Cancer Cells by Downregulating the Expression of Their Receptors. Horm Cancer. 2018 Jun;9(3):166-174. doi: 10.1007/s12672-018-0331-z. Epub 2018 Mar 30.
91 A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor. Mol Hum Reprod. 2005 Jul;11(7):471-6. doi: 10.1093/molehr/gah186.
92 Regulation of A Disintegrin And Metalloproteinase with ThromboSpondin repeats-1 expression in human endometrial stromal cells by gonadal steroids involves progestins, androgens, and estrogens. J Clin Endocrinol Metab. 2006 Dec;91(12):4825-35. doi: 10.1210/jc.2006-1567. Epub 2006 Oct 3.
93 Role of HERV-W syncytin-1 in placentation and maintenance of human pregnancy. Appl Immunohistochem Mol Morphol. 2009 Jul;17(4):319-28. doi: 10.1097/PAI.0b013e31819640f9.
94 Analysis of androgen receptor and anti-Mllerian hormone pathways in human granulosa cells under luteinizing hormone treatment. Reprod Biol Endocrinol. 2013 Feb 21;11:11. doi: 10.1186/1477-7827-11-11.
95 The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. Biochemistry. 2008 Aug 12;47(32):8261-70. doi: 10.1021/bi800572s. Epub 2008 Jul 15.
96 Gonadotrophin stimulation of non-luteinized granulosa cells increases steroid production and the expression of enzymes involved in estrogen and progesterone synthesis. Hum Reprod. 2007 Feb;22(2):401-6. doi: 10.1093/humrep/del408. Epub 2006 Nov 10.
97 Steroid signalling in the ovarian surface epithelium. Trends Endocrinol Metab. 2005 Sep;16(7):327-33.
98 Human steroidogenic factor-1 (hSF-1) regulates progesterone biosynthesis and growth of ovarian surface epithelial cancer cells. J Steroid Biochem Mol Biol. 2010 Mar;119(1-2):14-25. doi: 10.1016/j.jsbmb.2009.11.006. Epub 2010 Jan 4.
99 Human types 1 and 3 3 alpha-hydroxysteroid dehydrogenases: differential lability and tissue distribution. J Clin Endocrinol Metab. 2001 Feb;86(2):841-6. doi: 10.1210/jcem.86.2.7216.
100 [Stimulation of HCG, estrogen and progesterone production in isolated trophoblast cells by glycodelin A or its N-glycans]. Z Geburtshilfe Neonatol. 2005 Apr;209(2):59-64. doi: 10.1055/s-2005-864115.
101 Melatonin exerts direct inhibitory actions on ACTH responses in the human adrenal gland. Horm Metab Res. 2011 May;43(5):337-42. doi: 10.1055/s-0031-1271693. Epub 2011 Feb 17.
102 Effects of the insecticide amitraz, an alpha2-adrenergic receptor agonist, on human luteinized granulosa cells. Hum Reprod. 2005 Nov;20(11):3018-25. doi: 10.1093/humrep/dei194. Epub 2005 Aug 5.
103 AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. J Affect Disord. 2011 Sep;133(1-2):346-51. doi: 10.1016/j.jad.2011.04.009. Epub 2011 May 12.
104 Expression profile analysis of colon cancer cells in response to sulindac or aspirin. Biochem Biophys Res Commun. 2002 Mar 29;292(2):498-512.
105 Effects of aspirin on metastasis-associated gene expression detected by cDNA microarray. Acta Pharmacol Sin. 2004 Oct;25(10):1327-33.
106 Expression profile analysis of human peripheral blood mononuclear cells in response to aspirin. Arch Immunol Ther Exp (Warsz). 2005 Mar-Apr;53(2):151-8.
107 Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line. Oncol Rep. 2010 Jul;24(1):37-46. doi: 10.3892/or_00000826.
108 Aspirin-sensitive rhinitis-associated changes in upper airway innervation. Eur Respir J. 2003 Dec;22(6):986-91. doi: 10.1183/09031936.03.00086002.
109 Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by perturbing peroxisome proliferator-activated receptor-delta transcriptional pathway. Mol Pharmacol. 2008 Nov;74(5):1399-406. doi: 10.1124/mol.108.049569. Epub 2008 Aug 4.
110 Aspirin induces apoptosis through the blockade of IL-6-STAT3 signaling pathway in human glioblastoma A172 cells. Biochem Biophys Res Commun. 2009 Sep 18;387(2):342-7. doi: 10.1016/j.bbrc.2009.07.022. Epub 2009 Jul 10.
111 Association analysis of UBE3C polymorphisms in Korean aspirin-intolerant asthmatic patients. Ann Allergy Asthma Immunol. 2010 Oct;105(4):307-312. doi: 10.1016/j.anai.2010.07.006.
112 Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway. Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):538-45.
113 VKORC1-1639 G>A Polymorphism and the Risk of Non-Variceal Upper Gastrointestinal Bleeding. J Gastrointestin Liver Dis. 2017 Mar;26(1):13-18. doi: 10.15403/jgld.2014.1121.261.vko.
114 Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. J Biol Chem. 2004 Jul 2;279(27):28320-9. doi: 10.1074/jbc.M401396200. Epub 2004 Apr 26.
115 Cyclooxygenase inhibitors: instrumental drugs to understand cardiovascular homeostasis and arterial thrombosis. Cardiovasc Hematol Disord Drug Targets. 2008 Dec;8(4):268-77.
116 Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. Int J Pharm. 2003 Sep 16;263(1-2):113-22.
117 Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett. 1998 Jun 12;429(2):179-82.
118 Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter. J Biol Chem. 2010 Aug 20;285(34):26107-13.
119 A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter. Am J Physiol Cell Physiol. 2012 Jun 1;302(11):C1652-60.
120 Pharmacogenomics in aspirin intolerance. Curr Drug Metab. 2009 Nov;10(9):998-1008.
121 Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agents. Curr Drug Metab. 2006 Oct;7(7):745-53.
122 Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria. Allergy Asthma Immunol Res. 2011 Oct;3(4):273-6.
123 Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects. Clin Pharmacol Ther. 2003 Mar;73(3):264-71.
124 Association analysis of N-acetyl transferase-2 polymorphisms with aspirin intolerance among asthmatics. Pharmacogenomics. 2010 Jul;11(7):951-8. doi: 10.2217/pgs.10.65.
125 Interactions of human organic anion transporters and human organic cation transporters with nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2002 Nov;303(2):534-9.
126 Prolonged use of aspirin alters human and rat intestinal cells and thereby limits the absorption of clopidogrel. Clin Pharmacol Ther. 2011 Oct;90(4):612-9. doi: 10.1038/clpt.2011.163. Epub 2011 Sep 7.
127 The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria. Clin Exp Allergy. 2005 Mar;35(3):339-44. doi: 10.1111/j.1365-2222.2004.02197.x.
128 Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. J Clin Oncol. 2009 Dec 10;27(35):5972-8.
129 DNA array analysis of the effects of aspirin on colon cancer cells: involvement of Rac1. Carcinogenesis. 2004 Jul;25(7):1293-8.
130 Magnitude and time course of platelet inhibition with Aggrenox and Aspirin in patients after ischemic stroke: the AGgrenox versus Aspirin Therapy Evaluation (AGATE) trial. Eur J Pharmacol. 2004 Sep 24;499(3):315-24. doi: 10.1016/j.ejphar.2004.07.114.
131 A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet. 2010 Aug;42(8):711-4. doi: 10.1038/ng.632. Epub 2010 Jul 18.
132 A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma. Immunogenetics. 2011 Jan;63(1):13-21. doi: 10.1007/s00251-010-0490-8. Epub 2010 Nov 18.
133 Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D. Transl Psychiatry. 2012 Jul 3;2(7):e129. doi: 10.1038/tp.2012.57.
134 Aspirin-mediated COX-2 transcript stabilization via sustained p38 activation in human intestinal myofibroblasts. Mol Pharmacol. 2004 Feb;65(2):470-8.
135 Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. Biochem J. 2006 Feb 15;394(Pt 1):317-24.
136 Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. Chem Biol Interact. 2009 Mar 16;178(1-3):221-7.
137 Lunasin, a novel seed peptide, sensitizes human breast cancer MDA-MB-231 cells to aspirin-arrested cell cycle and induced apoptosis. Chem Biol Interact. 2010 Jul 30;186(2):127-34. doi: 10.1016/j.cbi.2010.04.027. Epub 2010 May 21.
138 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
139 Aspirin enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in hormone-refractory prostate cancer cells through survivin down-regulation. Mol Pharmacol. 2007 Dec;72(6):1586-92. doi: 10.1124/mol.107.039610. Epub 2007 Sep 11.
140 Aspirin induces apoptosis in human leukemia cells independently of NF-kappaB and MAPKs through alteration of the Mcl-1/Noxa balance. Apoptosis. 2010 Feb;15(2):219-29. doi: 10.1007/s10495-009-0424-9.
141 Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin. Biochem Pharmacol. 2004 Feb 1;67(3):411-9. doi: 10.1016/j.bcp.2003.09.014.
142 Sudden onset of ornithine carbamoyltransferase deficiency after aspirin ingestion. J Inherit Metab Dis. 1993;16(5):917. doi: 10.1007/BF00714301.
143 Antithrombotic effects of aspirin based on PLA1/A2 glycoprotein IIIa polymorphism in patients with coronary artery disease. Thromb Res. 2007;119(3):301-3. doi: 10.1016/j.thromres.2006.03.005. Epub 2006 May 3.
144 Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines. Hypertension. 2009 Nov;54(5):1136-42. doi: 10.1161/HYPERTENSIONAHA.109.134825. Epub 2009 Oct 5.
145 Aspirin inhibits MMP-2 and MMP-9 expressions and activities through upregulation of PPARalpha/gamma and TIMP gene expressions in ox-LDL-stimulated macrophages derived from human monocytes. Pharmacology. 2009;83(1):18-25. doi: 10.1159/000166183. Epub 2008 Oct 30.
146 Moderation of the platelet releasate response by aspirin. Blood. 2007 Jun 1;109(11):4786-92. doi: 10.1182/blood-2006-07-038539. Epub 2007 Feb 15.
147 Aspirin inhibits ErbB2 to induce apoptosis in cervical cancer cells. Med Oncol. 2010 Jun;27(2):379-87. doi: 10.1007/s12032-009-9221-0. Epub 2009 May 8.
148 The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells. Mol Carcinog. 2010 Mar;49(3):235-46. doi: 10.1002/mc.20593.
149 Aspirin Has Antitumor Effects via Expression of Calpain Gene in Cervical Cancer Cells. J Oncol. 2008;2008:285374. doi: 10.1155/2008/285374. Epub 2008 Sep 29.
150 A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro. Cancer Chemother Pharmacol. 2008 Feb;61(2):203-14. doi: 10.1007/s00280-007-0462-3. Epub 2007 Apr 20.
151 Aspirin induces apoptosis through release of cytochrome c from mitochondria. Neoplasia. 2000 Nov-Dec;2(6):505-13. doi: 10.1038/sj.neo.7900120.
152 Aspirin regulates hepatocellular lipid metabolism by activating AMPK signaling pathway. J Toxicol Sci. 2015 Feb;40(1):127-36. doi: 10.2131/jts.40.127.
153 Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. Dig Dis Sci. 2010 Jan;55(1):54-9. doi: 10.1007/s10620-008-0701-4. Epub 2009 Jan 29.
154 Aspirin-induced blockade of NF-kappaB activity restrains up-regulation of glial fibrillary acidic protein in human astroglial cells. Biochim Biophys Acta. 2006 Mar;1763(3):282-9. doi: 10.1016/j.bbamcr.2006.01.005. Epub 2006 Feb 21.
155 Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis. Oncogene. 2001 Sep 27;20(43):6250-7. doi: 10.1038/sj.onc.1204791.
156 Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A. Oncogene. 2006 Oct 19;25(49):6447-56. doi: 10.1038/sj.onc.1209658. Epub 2006 Jul 31.
157 Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. Aging (Albany NY). 2012 Dec;4(12):952-65. doi: 10.18632/aging.100521.
158 Effects of low-dose aspirin on acute inflammatory responses in humans. J Immunol. 2009 Aug 1;183(3):2089-96. doi: 10.4049/jimmunol.0900477. Epub 2009 Jul 13.
159 [Aspirin inhibits proliferation and expression of p44/42 MAPK phosphorylation in vascular endothelial cells]. Di Yi Jun Yi Da Xue Xue Bao. 2004 Sep;24(9):1013-5.
160 Lack of uniform platelet activation in patients after ischemic stroke and choice of antiplatelet therapy. Thromb Res. 2004;113(3-4):197-204. doi: 10.1016/j.thromres.2004.03.002.
161 Restoration by aspirin of impaired plasma maspin level in human breast cancer. Acta Oncol. 2006;45(2):184-7. doi: 10.1080/02841860500516584.
162 Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels. Clin Cancer Res. 2008 May 15;14(10):3168-76. doi: 10.1158/1078-0432.CCR-07-4362.
163 Advantageous use of HepaRG cells for the screening and mechanistic study of drug-induced steatosis. Toxicol Appl Pharmacol. 2016 Jul 1;302:1-9. doi: 10.1016/j.taap.2016.04.007. Epub 2016 Apr 16.
164 Role of mitochondria in aspirin-induced apoptosis in human gastric epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2005 Oct;289(4):G731-8. doi: 10.1152/ajpgi.00150.2005. Epub 2005 Jun 23.
165 Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes. Cytokine. 1999 May;11(5):347-58. doi: 10.1006/cyto.1998.0437.
166 Effects of acidic non-steroidal anti-inflammatory drugs on human cytochrome P450 4A11 activity: Roles of carboxylic acid and a sulfur atom in potent inhibition by sulindac sulfide. Chem Biol Interact. 2023 Sep 1;382:110644. doi: 10.1016/j.cbi.2023.110644. Epub 2023 Jul 25.
167 Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis. Br J Cancer. 2004 Jul 19;91(2):381-8. doi: 10.1038/sj.bjc.6601913.
168 Failure of apoptosis and activation on NFkappaB by celecoxib and aspirin in lung cancer cell lines. Oncol Rep. 2007 Apr;17(4):823-8.
169 Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak. Carcinogenesis. 2001 Sep;22(9):1393-7. doi: 10.1093/carcin/22.9.1393.
170 Low-dose aspirin reduces the gene expression of gastrokine-1 in the antral mucosa of healthy subjects. Aliment Pharmacol Ther. 2008 Sep 15;28(6):782-8. doi: 10.1111/j.1365-2036.2008.03793.x.
171 Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity. J Clin Immunol. 2007 Nov;27(6):613-9. doi: 10.1007/s10875-007-9115-x. Epub 2007 Jul 20.
172 KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma. J Clin Immunol. 2011 Feb;31(1):112-21. doi: 10.1007/s10875-010-9462-x. Epub 2010 Oct 5.
173 Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population. BMC Med Genet. 2010 Sep 23;11:138. doi: 10.1186/1471-2350-11-138.
174 Variable number of tandem repeats polymorphism of platelet glycoprotein Ib alpha in Chinese people and CC genotype with aspirin sensitivity in patients with cerebral infarction. J Clin Pharm Ther. 2009 Apr;34(2):239-43. doi: 10.1111/j.1365-2710.2008.00992.x.
175 Association analysis of RGS7BP gene polymorphisms with aspirin intolerance in asthmatic patients. Ann Allergy Asthma Immunol. 2011 Apr;106(4):292-300.e6. doi: 10.1016/j.anai.2010.10.021. Epub 2011 Jan 8.
176 Variations in the STK10 gene and possible associations with aspirin-intolerant asthma in a Korean population. J Investig Allergol Clin Immunol. 2011;21(5):378-88.
177 Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. Biol Pharm Bull. 1997 Aug;20(8):869-73. doi: 10.1248/bpb.20.869.
178 Possible association of SLC22A2 polymorphisms with aspirin-intolerant asthma. Int Arch Allergy Immunol. 2011;155(4):395-402. doi: 10.1159/000321267. Epub 2011 Feb 22.
179 Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria. Br J Dermatol. 2010 Nov;163(5):977-85. doi: 10.1111/j.1365-2133.2010.09983.x.
180 Adenosine deaminase and adenosine receptor polymorphisms in aspirin-intolerant asthma. Respir Med. 2009 Mar;103(3):356-63. doi: 10.1016/j.rmed.2008.10.008. Epub 2008 Nov 18.
181 Genetic and ethnic risk factors associated with drug hypersensitivity. Curr Opin Allergy Clin Immunol. 2010 Aug;10(4):280-90. doi: 10.1097/ACI.0b013e32833b1eb3.
182 Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population. Ann Hum Genet. 2010 Jul;74(4):326-34.
183 A polymorphism of MS4A2 (- 109T > C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FcepsilonR1beta) is associated with a susceptibility to aspirin-intolerant asthma. Clin Exp Allergy. 2006 Jul;36(7):877-83. doi: 10.1111/j.1365-2222.2006.02443.x.
184 Putative association of SMAPIL polymorphisms with risk of aspirin intolerance in asthmatics. J Asthma. 2010 Nov;47(9):959-65. doi: 10.1080/02770903.2010.514637.
185 Plasma levels of the growth arrest-specific gene 6 product (Gas6) and antiplatelet drug responsiveness in healthy subjects. J Thromb Haemost. 2006 Oct;4(10):2283-4. doi: 10.1111/j.1538-7836.2006.02155.x.
186 ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients. Gastroenterology. 2010 Oct;139(4):1190-7. doi: 10.1053/j.gastro.2010.06.071. Epub 2010 Jul 14.
187 ADAM33 polymorphisms are associated with aspirin-intolerant asthma in the Japanese population. J Hum Genet. 2007;52(1):66-72. doi: 10.1007/s10038-006-0081-6. Epub 2006 Oct 24.
188 Association of beta 2-adrenergic receptor polymorphism with the phenotype of aspirin-intolerant acute urticaria. Yonsei Med J. 2007 Dec 31;48(6):1079-81. doi: 10.3349/ymj.2007.48.6.1079.
189 Pharmacogenetics of ABCG2 and adverse reactions to gefitinib. J Natl Cancer Inst. 2006 Dec 6;98(23):1739-42.
190 Genetic association analysis of TAP1 and TAP2 polymorphisms with aspirin exacerbated respiratory disease and its FEV1 decline. J Hum Genet. 2011 Sep;56(9):652-9. doi: 10.1038/jhg.2011.75. Epub 2011 Jul 28.
191 Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study. BMC Pulm Med. 2010 Jun 1;10:34. doi: 10.1186/1471-2466-10-34.
192 Galectin-10 mRNA is overexpressed in peripheral blood of aspirin-induced asthma. Allergy. 2008 Jan;63(1):125-31. doi: 10.1111/j.1398-9995.2007.01558.x. Epub 2007 Oct 15.
193 Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. PLoS One. 2010 Nov 3;5(11):e13818. doi: 10.1371/journal.pone.0013818.
194 Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma. J Allergy Clin Immunol. 2009 Oct;124(4):779-85.e6. doi: 10.1016/j.jaci.2009.07.044. Epub 2009 Sep 19.