Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCT3I8)

Drug Name
Ifosfamide Drug Info
Synonyms
Cyfos; Holoxan; Ifex; Ifosfamid; Ifosfamida; Ifosfamidum; Ifosphamide; Ifsofamide; Iphosphamid; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Isosfamide; Mitoxana; Naxamide; Ifosfamide Sterile; Iso Endoxan; A 4942; ASTA Z 4942; Holoxan 1000; MJF 9325; Z 4942; Z4942; I-Phosphamide; IFEX (TN); Ifex (TN); Ifosfamida [INN-Spanish]; Ifosfamidum [INN-Latin]; Iphosphamid(e); Iso-Endoxan; MJF-9325; Mitoxana (TN); NPFAPI-04; Z-4942; Mitoxana, Ifex, Ifosfamide; Ifosfamide (JAN/USP/INN); Ifosfamide [USAN:INN:BAN:JAN]; N,N-Bis(beta-chloroethyl)-amino-N',O-propylene-phosphoric acid ester diamide; N,3-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide; N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylen ephosphoric acid diamide; N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide; N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide; N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid ester diamide; N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid; N-(2-Chloraethyl)-N'-(2-chloraethyl)-N',O-propylen-phosphorsaureester-diamid [German]; N-(2-Chloroethyl)-N-(3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amine; (+-)-Ifosfamid; (+-)-Ifosphamide; (+-)-Tetrahydro-N,3-bis(2-chloroethyl)-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; (D,L)-Ifosfamide; (R,S)-Ifosphamide; (R,S)-N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; 1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide; 1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; 2,3-(N,N(sup 1)-Bis(2-chloroethyl)diamido)-1,3,2-oxazaphosphoridinoxyd; 2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxyd; 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (8CI); 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; 3,} 2-oxazaphosphorine oxide; 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)perhydro-2H-1,3,2-oxazaphosphorine oxide; 3-(2-Chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorine oxide; 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide; 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
Indication
Disease Entry ICD 11 Status REF
Adult central nervous system germ cell tumor Approved [1]
Adult teratoma Approved [1]
Advanced cancer 2A00-2F9Z Approved [1]
Extragonadal germ cell cancer Approved [1]
Extragonadal germ cell tumor Approved [1]
Kidney neoplasm Approved [1]
Solid tumour/cancer 2A00-2F9Z Approved [2]
Testicular germ cell tumor Approved [1]
Extragonadal nonseminomatous germ cell tumor Investigative [1]
Extragonadal seminoma Investigative [1]
Neuroblastoma 2D11.2 Investigative [1]
Retinoblastoma 2D02.2 Investigative [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
3690
ChEBI ID
CHEMBL1024
CAS Number
CAS 3778-73-2
TTD Drug ID
DMCT3I8
INTEDE Drug ID
DR0855
ACDINA Drug ID
D01151

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Human Deoxyribonucleic acid (hDNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [13]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [14]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [15]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [16]
Carboplatin DMG281S Adenocarcinoma 2D40 Approved [17]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [18]
Procarbazine DMIK367 Hodgkin lymphoma 2B30 Approved [19]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [20]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [21]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [22]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [23]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [25]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [26]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [27]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [28]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [29]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [30]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [24]
Verapamil DMA7PEW Angina pectoris BA40 Approved [4]
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Drug(s) Metabolized By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [31]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [10]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [32]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [27]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Metronidazole DMTIVEN Abscess Approved [34]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [35]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [36]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [10]
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Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [41]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [44]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [40]
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Drug(s) Metabolized By Cytochrome P450 3A7 (CYP3A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [46]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [40]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [40]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [10]
Verapamil DMA7PEW Angina pectoris BA40 Approved [47]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [40]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [40]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [40]
Metronidazole DMTIVEN Abscess Approved [34]
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Drug(s) Metabolized By Cytochrome P450 2C18 (CYP2C18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [10]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [48]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [35]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Diazepam DM08E9O Alcohol withdrawal Approved [50]
Methadone DMTW6IU Advanced cancer 2A00-2F9Z Approved [51]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [52]
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [10]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [53]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [54]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [54]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [10]
Verapamil DMA7PEW Angina pectoris BA40 Approved [55]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [56]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [57]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [54]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [58]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [35]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [59]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [60]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [61]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [10]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [62]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [10]
Verapamil DMA7PEW Angina pectoris BA40 Approved [63]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [64]
Estrone DM5T6US Acne vulgaris ED80 Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [66]
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Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [67]
Verapamil DMA7PEW Angina pectoris BA40 Approved [10]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [68]
Estrone DM5T6US Acne vulgaris ED80 Approved [61]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [70]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [71]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [72]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [73]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [74]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [75]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [59]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [76]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [77]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [10]
Verapamil DMA7PEW Angina pectoris BA40 Approved [78]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [66]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [79]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [35]
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Drug(s) Metabolized By Prostaglandin G/H synthase 1 (COX-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [4]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [80]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [4]
Diazepam DM08E9O Alcohol withdrawal Approved [4]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [4]
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [4]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [4]
Ketobemidone DMM3L6Z Pain MG30-MG3Z Approved [4]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [4]
Terbinafine DMI6HUW Fungal infection 1F29-1F2F Approved [4]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [81]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [82]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [83]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [84]
Capsaicin DMGMF6V Back pain ME84.Z Approved [85]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [86]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [87]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [86]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [82]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [12]
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Drug(s) Affected By Alpha-2A adrenergic receptor (ADRA2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Rilmenidine DM13PQW Hypertension BA00-BA04 Approved [89]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Indapamide DMGN1PW Edema MG29 Approved [96]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [97]
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Drug(s) Affected By Solute carrier family 12 member 8 (SLC12A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [102]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
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Drug(s) Affected By Agrin (AGRN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [106]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [109]
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Drug(s) Affected By Podocalyxin (PODXL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Folic Acid DMEMBJC Colorectal carcinoma Approved [114]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
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Drug(s) Affected By Class E basic helix-loop-helix protein 40 (BHLHE40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
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Drug(s) Affected By TRAF-type zinc finger domain-containing protein 1 (TRAFD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [125]
Bortezomib DMNO38U Leukemia Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [127]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [128]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [131]
Selenium DM25CGV N. A. N. A. Approved [132]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [133]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [133]
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Drug(s) Affected By Rho guanine nucleotide exchange factor 10 (ARHGEF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
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Drug(s) Affected By Apoptosis regulatory protein Siva (SIVA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Bortezomib DMNO38U Leukemia Approved [138]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
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Drug(s) Affected By Transcription factor MafG (MAFG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [142]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
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Drug(s) Affected By E3 ubiquitin-protein ligase SIAH2 (SIAH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [145]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Estrone DM5T6US Acne vulgaris ED80 Approved [144]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [146]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein regulator of cytokinesis 1 (PRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [147]
Methotrexate DM2TEOL Anterior urethra cancer Approved [109]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
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Drug(s) Affected By TP53-regulated inhibitor of apoptosis 1 (TRIAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [151]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Testosterone enanthate DMB6871 N. A. N. A. Approved [153]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [156]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NUAK family SNF1-like kinase 1 (NUAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [157]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [159]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
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Drug(s) Affected By PR domain zinc finger protein 1 (PRDM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [162]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ibrutinib DMHZCPO Mantle cell lymphoma 2A85.5 Approved [164]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [165]
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Drug(s) Affected By E3 ubiquitin-protein ligase listerin (LTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [166]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor alpha-induced protein 8 (TNFAIP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [169]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [170]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-12 (TSPAN12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Folic Acid DMEMBJC Colorectal carcinoma Approved [173]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [174]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
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Drug(s) Affected By Fructose-bisphosphate aldolase A (ALDOA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Etretinate DM2CZFA Keratosis ED56 Approved [175]
Methotrexate DM2TEOL Anterior urethra cancer Approved [176]
Quercetin DM3NC4M Obesity 5B81 Approved [177]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [146]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [179]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fatty acid-binding protein, heart (FABP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [180]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [181]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Haloperidol DM96SE0 Delirium Approved [182]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Benzatropine DMF7EXL Parkinsonian disorder Approved [182]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [183]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Methamphetamine DMPM4SK Anxiety Approved [184]
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Drug(s) Affected By Transcription factor AP-2-alpha (TFAP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [185]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [144]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [186]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycogen phosphorylase, liver form (PYGL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amino acid transporter heavy chain SLC3A2 (SLC3A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [159]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [190]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [170]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-enolase (ENO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [191]
Estrone DM5T6US Acne vulgaris ED80 Approved [192]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [193]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [194]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein RO60 (RO60)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Selenium DM25CGV N. A. N. A. Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [196]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [197]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [198]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [181]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [182]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [199]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cation-independent mannose-6-phosphate receptor (IGF2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [200]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [146]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Folic Acid DMEMBJC Colorectal carcinoma Approved [173]
Menthol DMG2KW7 Back pain ME84.Z Approved [201]
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Drug(s) Affected By Protein SON (SON)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [202]
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [205]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [206]
Selenium DM25CGV N. A. N. A. Approved [104]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [159]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [207]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [208]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [142]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [209]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [210]
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Drug(s) Affected By Keratin, type I cytoskeletal 15 (KRT15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [211]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [212]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [212]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
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Drug(s) Affected By Ephrin-A1 (EFNA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [213]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Estrone DM5T6US Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
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Drug(s) Affected By Ferrochelatase, mitochondrial (FECH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [206]
Selenium DM25CGV N. A. N. A. Approved [104]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [214]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [165]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [143]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
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Drug(s) Affected By Diacylglycerol kinase alpha (DGKA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [215]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [156]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
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Drug(s) Affected By DnaJ homolog subfamily B member 2 (DNAJB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [217]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [218]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
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Drug(s) Affected By Threonine--tRNA ligase 1, cytoplasmic (TARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [182]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [202]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
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Drug(s) Affected By Adenylate kinase 4, mitochondrial (AK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Folic Acid DMEMBJC Colorectal carcinoma Approved [114]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ETS domain-containing protein Elk-4 (ELK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [221]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Folic Acid DMEMBJC Colorectal carcinoma Approved [173]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase receptor UFO (AXL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [222]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [211]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [222]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [223]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 14-3-3 protein sigma (SFN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [224]
Gefitinib DM15F0X Colon adenocarcinoma Approved [225]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [222]
Quercetin DM3NC4M Obesity 5B81 Approved [227]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [222]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [228]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Benzatropine DMF7EXL Parkinsonian disorder Approved [182]
Clozapine DMFC71L Schizophrenia 6A20 Approved [182]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Long-chain-fatty-acid--CoA ligase 1 (ACSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [157]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [210]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [230]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thrombospondin-2 (THBS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [202]
Quercetin DM3NC4M Obesity 5B81 Approved [145]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [232]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [233]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [234]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [205]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [130]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [235]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [236]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [237]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transaldolase (TALDO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [238]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [239]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [240]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [241]
Gefitinib DM15F0X Colon adenocarcinoma Approved [242]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [243]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Etretinate DM2CZFA Keratosis ED56 Approved [244]
Prednisone DM2HG4X Acute asthma CA23 Approved [245]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [246]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycine--tRNA ligase (GARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [225]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [247]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [248]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [249]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Isoleucine--tRNA ligase, cytoplasmic (IARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [112]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [159]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [248]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [169]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [222]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [222]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [250]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 1 (EIF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [240]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [249]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinaldehyde dehydrogenase 3 (ALDH1A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [12]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [252]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine--tRNA ligase, cytoplasmic (CARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [190]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [253]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine--tRNA ligase, cytoplasmic (SARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Haloperidol DM96SE0 Delirium Approved [182]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Benzatropine DMF7EXL Parkinsonian disorder Approved [182]
Clozapine DMFC71L Schizophrenia 6A20 Approved [182]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [255]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Max-interacting protein 1 (MXI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [256]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [257]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [97]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [258]
Diazepam DM08E9O Alcohol withdrawal Approved [259]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [260]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [258]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [261]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [258]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [262]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ataxin-1 (ATXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [157]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Selenium DM25CGV N. A. N. A. Approved [104]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [166]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein DLX-1 (DLX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [265]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein BTG2 (BTG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [266]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [267]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [268]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large neutral amino acids transporter small subunit 1 (SLC7A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [144]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [206]
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [256]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [228]
Estrone DM5T6US Acne vulgaris ED80 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 94 (TMEM94)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [269]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [270]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [271]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [203]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [203]
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Drug(s) Affected By BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [206]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [211]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [170]
Quinolones DM5GVHU Bacterial infection 1A00-1C4Z Approved [272]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [273]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [274]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein Rlf (RLF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase G (PPIG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [146]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Testosterone enanthate DMB6871 N. A. N. A. Approved [153]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
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Drug(s) Affected By Ras-related protein Rab-31 (RAB31)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
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Drug(s) Affected By Kelch-like ECH-associated protein 1 (KEAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [275]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
Selenium DM25CGV N. A. N. A. Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [277]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [278]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [279]
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Drug(s) Affected By Src substrate cortactin (CTTN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [280]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Clozapine DMFC71L Schizophrenia 6A20 Approved [182]
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Drug(s) Affected By Protein disulfide-isomerase A5 (PDIA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [152]
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Drug(s) Affected By Condensin complex subunit 1 (NCAPD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [281]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [232]
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Drug(s) Affected By Probable E3 ubiquitin-protein ligase HERC3 (HERC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [282]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [283]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [284]
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Drug(s) Affected By kinase isozyme 1, mitochondrial (PDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [116]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [285]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [286]
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Drug(s) Affected By Neutral amino acid transporter B(0) (SLC1A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [127]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [127]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [287]
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Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Fluoxetine DM3PD2C Bipolar depression Approved [190]
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Estrone DM5T6US Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
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Drug(s) Affected By Neuronal regeneration-related protein (NREP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [288]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Folic Acid DMEMBJC Colorectal carcinoma Approved [114]
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Drug(s) Affected By Laminin subunit alpha-3 (LAMA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [212]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [212]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Atos homolog protein A (ATOSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [116]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [265]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
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Drug(s) Affected By Glycerol-3-phosphate acyltransferase 3 (GPAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [162]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [290]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [254]
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Drug(s) Affected By Quinone oxidoreductase PIG3 (TP53I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [291]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [293]
Amifostine DM5FL14 Mucositis CA00 Approved [294]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RRP12-like protein (RRP12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [162]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [296]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [297]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ALS2 C-terminal-like protein (ALS2CL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [165]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dynamin-binding protein (DNMBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [297]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [299]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [297]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [300]
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Drug(s) Affected By Ribosomal protein eS27-like (RPS27L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [249]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
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Drug(s) Affected By Arginine/serine-rich coiled-coil protein 2 (RSRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [301]
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Drug(s) Affected By Mitochondrial enolase superfamily member 1 (ENOSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [302]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [152]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [303]
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Drug(s) Affected By Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [304]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [304]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
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Drug(s) Affected By Protein LYRIC (MTDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [297]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [305]
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Drug(s) Affected By Liprin-beta-1 (PPFIBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [166]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
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Drug(s) Affected By Dynein axonemal intermediate chain 3 (DNAI3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [306]
Lucanthone DMZLBUO Solid tumour/cancer 2A00-2F9Z Approved [307]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [308]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [305]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [251]
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Drug(s) Affected By Protein O-mannosyl-transferase TMTC2 (TMTC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [254]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [309]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
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Drug(s) Affected By Ninein (NIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [310]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Tubocurarine DMBZIVP Anaesthesia 9A78.6 Approved [311]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [111]
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Drug(s) Affected By Ceramide synthase 5 (CERS5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [312]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
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Drug(s) Affected By Uncharacterized protein C8orf58 (C8ORF58)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [308]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [305]
Milchsaure DM462BT Pruritus EC90 Investigative [313]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [314]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 22 (FBXO22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Folic Acid DMEMBJC Colorectal carcinoma Approved [173]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [218]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By (Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [232]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [315]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 30 (FBXO30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [290]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pantothenate kinase 1 (PANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [117]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [165]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SH3 domain and tetratricopeptide repeat-containing protein 1 (SH3TC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [162]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C4orf3 (C4ORF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Bortezomib DMNO38U Leukemia Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paraspeckle component 1 (PSPC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [116]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [317]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [318]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase rififylin (RFFL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [249]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable ATP-dependent RNA helicase DDX17 (DDX17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [319]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Testosterone enanthate DMB6871 N. A. N. A. Approved [153]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding protein Rit1 (RIT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [315]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [125]
Bortezomib DMNO38U Leukemia Approved [126]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By KICSTOR complex protein ITFG2 (ITFG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [111]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein TMEPAI (PMEPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [320]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM162A (FAM162A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [170]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [153]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein p53-inducible nuclear protein 1 (TP53INP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [268]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SPRY domain-containing SOCS box protein 1 (SPSB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [315]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [322]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxymethylenebutenolidase homolog (CMBL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM89A (FAM89A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [111]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ERO1-like protein alpha (ERO1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [324]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [165]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM210B, mitochondrial (FAM210B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E1A-binding protein p400 (EP400)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [168]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [325]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [326]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [174]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [327]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ETS-related transcription factor Elf-4 (ELF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [146]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [218]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 3 subunit C (EIF3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [247]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [149]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [328]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [329]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cancer-related nucleoside-triphosphatase (NTPCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [330]
Ethacrynic acid DM60QMR Edema MG29 Approved [331]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G protein-coupled receptor 88 (GPR88)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [283]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [308]
Drug(s) Affected By Coiled-coil domain-containing protein 90B, mitochondrial (CCDC90B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [152]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [303]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [332]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polyprenol reductase (SRD5A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [269]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin ligase RNF121 (RNF121)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [157]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [333]
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Drug(s) Affected By Ankyrin repeat family A protein 2 (ANKRA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
Selenium DM25CGV N. A. N. A. Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By p53-induced death domain-containing protein 1 (PIDD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [328]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ABC-type oligopeptide transporter ABCB9 (ABCB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [334]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Urethane DM7NSI0 N. A. N. A. Phase 4 [160]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [335]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fructose-2,6-bisphosphatase TIGAR (TIGAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [94]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 22 (DUSP22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [218]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [336]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [337]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [305]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PAK4-inhibitor INKA2 (INKA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [323]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [218]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [338]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [99]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [339]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 4 protein (DDIT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [340]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [170]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [268]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By LIM and cysteine-rich domains protein 1 (LMCD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [341]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [232]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Signal-induced proliferation-associated 1-like protein 2 (SIPA1L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [342]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [255]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [108]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [125]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 9 (DNAJB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [233]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [142]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [343]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [233]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [254]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [341]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial fission process protein 1 (MTFP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SERTA domain-containing protein 1 (SERTAD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxidative stress-induced growth inhibitor 1 (OSGIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heme transporter FLVCR2 (FLVCR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [167]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exocyst complex component 7 (EXOC7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Methotrexate DM2TEOL Anterior urethra cancer Approved [345]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [270]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [203]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [108]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-1 (PRKAB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [11]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [346]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [127]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [127]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [338]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA polymerase II subunit A C-terminal domain phosphatase (CTDP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [11]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Testosterone enanthate DMB6871 N. A. N. A. Approved [153]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Arsenic DMTL2Y1 N. A. N. A. Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pleckstrin homology-like domain family A member 3 (PHLDA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [251]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [11]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-induced gene 2 protein (INSIG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [172]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [95]
Ethanol DMDRQZU Chronic pain MG30 Approved [347]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [11]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [139]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [348]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sestrin-1 (SESN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [349]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [268]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [248]
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [113]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [350]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [350]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [351]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [352]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [353]
Etidronic acid DM1XHYJ Bone Paget disease Approved [350]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [350]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [350]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [354]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [355]
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Drug(s) Affected By Osteocalcin (BGLAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [357]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [358]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [359]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [360]
Pamidronate DMB4AVP Bone Paget disease Approved [361]
Falecalcitrol DMBI9ZJ Hyperparathyroidism 5A51 Approved [362]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [363]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [365]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [366]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [367]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [368]
Cepharanthine DM9Y5JB N. A. N. A. Approved [369]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [370]
Clozapine DMFC71L Schizophrenia 6A20 Approved [371]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [372]
Trifluoperazine DMKBYWI Anxiety Approved [373]
Olanzapine DMPFN6Y Bipolar depression Approved [371]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HLA class I histocompatibility antigen, alpha chain G (HLA-G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [104]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [374]
Methotrexate DM2TEOL Anterior urethra cancer Approved [169]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [374]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [204]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [374]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [374]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [374]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione peroxidase 3 (GPX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Selenium DM25CGV N. A. N. A. Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [178]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [91]
Testosterone DM7HUNW Hot flushes GA30 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [375]
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Drug(s) Affected By Major histocompatibility complex class I-related gene protein (MR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [374]
Quercetin DM3NC4M Obesity 5B81 Approved [116]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [374]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [374]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [222]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [374]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [374]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [374]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Elastin (ELN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [376]
Etretinate DM2CZFA Keratosis ED56 Approved [377]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [188]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [378]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [232]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [379]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [103]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [284]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [380]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human Deoxyribonucleic acid (hDNA) TTUTN1I NOUNIPROTAC Modulator [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [4]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [5]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [6]
Cytochrome P450 2A6 (CYP2A6) DEJVYAZ CP2A6_HUMAN Substrate [7]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [8]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [9]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [8]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [10]
Prostaglandin G/H synthase 1 (COX-1) DE073H6 PGH1_HUMAN Substrate [4]
Cytochrome P450 2C18 (CYP2C18) DEZMWRE CP2CI_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4) OTQK3M9X ABHD4_HUMAN Gene/Protein Processing [11]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [11]
5'-AMP-activated protein kinase subunit beta-1 (PRKAB1) OT1OG4QZ AAKB1_HUMAN Gene/Protein Processing [11]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) OTLVN68B AAKB2_HUMAN Gene/Protein Processing [11]
ABC-type oligopeptide transporter ABCB9 (ABCB9) OTSOBOL5 ABCB9_HUMAN Gene/Protein Processing [11]
Adenylate kinase 4, mitochondrial (AK4) OTA0T02Q KAD4_HUMAN Gene/Protein Processing [11]
Agrin (AGRN) OTWJENAZ AGRIN_HUMAN Gene/Protein Processing [11]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [11]
Alpha-2A adrenergic receptor (ADRA2A) OTZFGOTP ADA2A_HUMAN Drug Response [12]
ALS2 C-terminal-like protein (ALS2CL) OT8RY7TZ AL2CL_HUMAN Gene/Protein Processing [11]

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132 Death receptor 5 regulation during selenium-mediated apoptosis in human prostate cancer cells. Cancer Biol Ther. 2002 May-Jun;1(3):287-90. doi: 10.4161/cbt.83.
133 Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. J Natl Cancer Inst. 2004 Dec 1;96(23):1769-80. doi: 10.1093/jnci/djh322.
134 Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014 Jan;66(1):15-23.
135 The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells. Leukemia. 2009 Jun;23(6):1019-28.
136 Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes. Toxicol Sci. 2015 Jan;143(1):97-106. doi: 10.1093/toxsci/kfu210. Epub 2014 Oct 10.
137 Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro. Toxicol In Vitro. 2015 Apr;29(3):489-501.
138 Bortezomib induces caspase-dependent apoptosis in Hodgkin lymphoma cell lines and is associated with reduced c-FLIP expression: a gene expression profiling study with implications for potential combination therapies. Leuk Res. 2008 Feb;32(2):275-85. doi: 10.1016/j.leukres.2007.05.024. Epub 2007 Jul 19.
139 Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper. Physiol Genomics. 2009 Aug 7;38(3):386-401.
140 Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1. Redox Biol. 2020 Jan;28:101321. doi: 10.1016/j.redox.2019.101321. Epub 2019 Sep 5.
141 Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. Cancer Res. 2002 Nov 1;62(21):6246-54.
142 Robustness testing and optimization of an adverse outcome pathway on cholestatic liver injury. Arch Toxicol. 2020 Apr;94(4):1151-1172. doi: 10.1007/s00204-020-02691-9. Epub 2020 Mar 10.
143 Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds. Toxicol Sci. 2010 Sep;117(1):81-9.
144 Moving toward integrating gene expression profiling into high-throughput testing: a gene expression biomarker accurately predicts estrogen receptor alpha modulation in a microarray compendium. Toxicol Sci. 2016 May;151(1):88-103.
145 Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro. Eur J Nutr. 2005 Mar;44(3):143-56. doi: 10.1007/s00394-004-0503-1. Epub 2004 Apr 30.
146 Expression profile analysis of human peripheral blood mononuclear cells in response to aspirin. Arch Immunol Ther Exp (Warsz). 2005 Mar-Apr;53(2):151-8.
147 Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
148 Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. World J Gastroenterol. 2009 Jan 21;15(3):310-20.
149 Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide. Med Oncol. 2011 Dec;28(4):1225-54.
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