Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMOMN31)

Drug Name
PEITC Drug Info
Synonyms Phenethyl-isothiocyanate
Indication
Disease Entry ICD 11 Status REF
Prostate cancer 2C82.0 Phase 2 [1]
Cross-matching ID
PubChem CID
16741
ChEBI ID
CHEMBL351346
CAS Number
CAS 2257-09-2
TTD Drug ID
DMOMN31
VARIDT Drug ID
DR01460
INTEDE Drug ID
DR1867

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [9]
Folic Acid DMEMBJC Colorectal carcinoma Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [11]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [12]
Verapamil DMA7PEW Angina pectoris BA40 Approved [3]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [13]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [14]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [15]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [16]
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Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Folic Acid DMEMBJC Colorectal carcinoma Approved [19]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [20]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [21]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [24]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [26]
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Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
Folic Acid DMEMBJC Colorectal carcinoma Approved [29]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [30]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [31]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [32]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [33]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [35]
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Drug(s) Metabolized By Glutathione S-transferase alpha-1 (GSTA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [36]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [37]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [38]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [39]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [40]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [41]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [42]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [43]
Ethacrynic acid DM60QMR Edema MG29 Approved [44]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [45]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Gefitinib DM15F0X Colon adenocarcinoma Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [51]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [53]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [54]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [56]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [58]
Gefitinib DM15F0X Colon adenocarcinoma Approved [59]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Etretinate DM2CZFA Keratosis ED56 Approved [62]
Prednisone DM2HG4X Acute asthma CA23 Approved [63]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [64]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
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Drug(s) Affected By Protein NDRG1 (NDRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [67]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [74]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
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Drug(s) Affected By DNA excision repair protein ERCC-5 (ERCC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Arsenic DMTL2Y1 N. A. N. A. Approved [79]
Ximelegatran DMU8ANS Myocardial infarction BA41-BA43 Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [81]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [82]
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Drug(s) Affected By DNA repair endonuclease XPF (ERCC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Testosterone DM7HUNW Hot flushes GA30 Approved [84]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Arsenic DMTL2Y1 N. A. N. A. Approved [88]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Bortezomib DMNO38U Leukemia Approved [91]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [92]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Gefitinib DM15F0X Colon adenocarcinoma Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [96]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [97]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [64]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [97]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [98]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [99]
Methotrexate DM2TEOL Anterior urethra cancer Approved [100]
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Drug(s) Affected By Matrilin-2 (MATN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [105]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [106]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
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Drug(s) Affected By Serine/threonine-protein kinase PLK4 (PLK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Paclitaxel DMLB81S Breast carcinoma Approved [111]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [112]
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Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [113]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [114]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [114]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [116]
Fluoxetine DM3PD2C Bipolar depression Approved [114]
Fructose DM43AN2 Vomiting MD90 Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [114]
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Drug(s) Affected By Histone-lysine N-methyltransferase SUV39H1 (SUV39H1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [121]
Bortezomib DMNO38U Leukemia Approved [122]
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Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [125]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [125]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Testosterone enanthate DMB6871 N. A. N. A. Approved [127]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
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Drug(s) Affected By Uncharacterized protein KIAA0513 (KIAA0513)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [129]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ethanol DMDRQZU Chronic pain MG30 Approved [130]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
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Drug(s) Affected By Myelin protein zero-like protein 2 (MPZL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Paclitaxel DMLB81S Breast carcinoma Approved [134]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [135]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
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Drug(s) Affected By Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [140]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
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Drug(s) Affected By Cell division control protein 45 homolog (CDC45)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [141]
Quercetin DM3NC4M Obesity 5B81 Approved [142]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [144]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
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Drug(s) Affected By F-box and WD repeat domain containing protein 10B (FBXW10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [149]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [150]
Drug(s) Affected By Kinesin-like protein KIF20A (KIF20A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
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Drug(s) Affected By Ferritin light chain (FTL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [153]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [154]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [156]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [158]
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Drug(s) Affected By Histone H2A type 1-B/E (H2AC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
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Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [164]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [167]
Quercetin DM3NC4M Obesity 5B81 Approved [168]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [169]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [170]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [171]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
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Drug(s) Affected By Vitamin K-dependent protein S (PROS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desogestrel DM27U4Y Contraception QA21 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Folic Acid DMEMBJC Colorectal carcinoma Approved [174]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
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Drug(s) Affected By DNA polymerase alpha catalytic subunit (POLA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [175]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [176]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [178]
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Drug(s) Affected By Histone H2A type 1 (H2AC11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [181]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
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Drug(s) Affected By Myb-related protein B (MYBL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [184]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [176]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [184]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [186]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
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Drug(s) Affected By Pregnancy-specific beta-1-glycoprotein 1 (PSG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [188]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [189]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
Drug(s) Affected By Transcription factor JunB (JUNB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [191]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [193]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [194]
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Drug(s) Affected By DNA ligase 1 (LIG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [195]
Paclitaxel DMLB81S Breast carcinoma Approved [111]
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Drug(s) Affected By Lamin-B1 (LMNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [196]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [197]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [198]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [199]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
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Drug(s) Affected By Diamine acetyltransferase 1 (SAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Selenium DM25CGV N. A. N. A. Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [200]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [201]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By COUP transcription factor 2 (NR2F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
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Drug(s) Affected By CD82 antigen (CD82)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Bortezomib DMNO38U Leukemia Approved [204]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase delta catalytic subunit (POLD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
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Drug(s) Affected By M-phase inducer phosphatase 3 (CDC25C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Methotrexate DM2TEOL Anterior urethra cancer Approved [207]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [210]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM5 (MCM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [211]
Selenium DM25CGV N. A. N. A. Approved [153]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [212]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [213]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [214]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [215]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [216]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Flap endonuclease 1 (FEN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-F (CCNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [218]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [219]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cathepsin O (CTSO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Selenium DM25CGV N. A. N. A. Approved [153]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [220]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [221]
AMEP DMFELMQ Melanoma 2C30 Phase 1 [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromobox protein homolog 5 (CBX5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Selenium DM25CGV N. A. N. A. Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [224]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [127]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein F (CENPF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA primase small subunit (PRIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [141]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM2 (MCM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [142]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [226]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Selenide, water dikinase 1 (SEPHS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [135]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [227]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [228]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [220]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [229]
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Drug(s) Affected By Rho GDP-dissociation inhibitor 2 (ARHGDIB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [230]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [52]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK1 (PLK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [231]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RecQ-like DNA helicase BLM (BLM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase epsilon subunit 2 (POLE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Period circadian protein homolog 3 (PER3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Selenium DM25CGV N. A. N. A. Approved [153]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [189]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Anaphase-promoting complex subunit 15 (ANAPC15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [153]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [233]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [234]
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Drug(s) Affected By Actin, aortic smooth muscle (ACTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [237]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [238]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [239]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [240]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H4 (H4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2B type 1-C/E/F/G/I (H2BC10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [243]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [161]
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Drug(s) Affected By Histone H3.1 (H3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Vigilin (HDLBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [244]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [245]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF23 (KIF23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [211]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [246]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [242]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [247]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase epsilon catalytic subunit A (POLE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [249]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Schlafen family member 5 (SLFN5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [181]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [250]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromatin assembly factor 1 subunit B (CHAF1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [65]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [65]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase alpha subunit B (POLA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Selenium DM25CGV N. A. N. A. Approved [153]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [251]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Separin (ESPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Folic Acid DMEMBJC Colorectal carcinoma Approved [174]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 2 (NCAPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [144]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Haloperidol DM96SE0 Delirium Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PCNA-associated factor (PCLAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [253]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [251]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [254]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pachytene checkpoint protein 2 homolog (TRIP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [255]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 3 (CDKN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [255]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA excision repair protein ERCC-6-like (ERCC6L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Renal cancer differentiation gene 1 protein (C4ORF46)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [256]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcriptional protein SWT1 (SWT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [135]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [257]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [259]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PHD finger protein 19 (PHF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [261]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pleckstrin homology domain-containing family A member 7 (PLEKHA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [262]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [189]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho GTPase-activating protein 11A (ARHGAP11A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein MCM10 homolog (MCM10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Radial spoke head protein 3 homolog (RSPH3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [150]
Milchsaure DM462BT Pruritus EC90 Investigative [265]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [266]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras GTPase-activating-like protein IQGAP3 (IQGAP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin-2 complex subunit G2 (NCAPG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF18B (KIF18B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spindle and kinetochore-associated protein 3 (SKA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [211]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nurim (NRM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [263]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [267]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [118]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rhotekin-2 (RTKN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [268]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Abnormal spindle-like microcephaly-associated protein (ASPM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [246]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein mono-ADP-ribosyltransferase PARP8 (PARP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [129]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [77]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [118]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [77]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [269]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxypeptidase A6 (CPA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [136]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [270]
OXYQUINOLINE DMZVS9Y Discovery agent N.A. Investigative [76]
NAPQI DM8F5LR Autoimmune disease 4A40-4A45 Investigative [271]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By T-complex protein 11-like protein 2 (TCP11L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [272]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leucine-rich repeat-containing protein 17 (LRRC17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [189]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [274]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Meiosis-specific nuclear structural protein 1 (MNS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spindle and kinetochore-associated protein 2 (SKA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein I (CENPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Folic Acid DMEMBJC Colorectal carcinoma Approved [174]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Type II iodothyronine deiodinase (DIO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [275]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [276]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [277]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [278]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [279]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [280]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2B type 1-H (H2BC9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [123]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 32 (FBXO32)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [281]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [262]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [281]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [181]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Unconventional myosin-XIX (MYO19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [123]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [282]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [244]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [283]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 4-hydroxybenzoate polyprenyltransferase, mitochondrial (COQ2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [284]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [285]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [286]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [118]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lymphokine-activated killer T-cell-originated protein kinase (PBK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [287]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2A type 1-H (H2AC12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [288]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [243]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [289]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [290]
Lucanthone DMZLBUO Solid tumour/cancer 2A00-2F9Z Approved [291]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leucine-rich repeat protein 1 (LRR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [256]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [292]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [267]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 (PCMTD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [294]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATPase family AAA domain-containing protein 5 (ATAD5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [268]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuroserpin (SERPINI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division cycle-associated protein 3 (CDCA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division control protein 6 homolog (CDC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [65]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [141]
Quercetin DM3NC4M Obesity 5B81 Approved [175]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [296]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 3 (NCAPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [46]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [281]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [297]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [298]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [297]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Racecadotril DMFOTZ7 Diarrhea ME05.1 Approved [299]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-CoA acetyltransferase, cytosolic (ACAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Clozapine DMFC71L Schizophrenia 6A20 Approved [300]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division cycle-associated protein 7 (CDCA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [302]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Paclitaxel DMLB81S Breast carcinoma Approved [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Meiotic nuclear division protein 1 homolog (MND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [230]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fanconi anemia group J protein (BRIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [204]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fanconi anemia group D2 protein (FANCD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [85]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [304]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [125]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [305]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
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Drug(s) Affected By DNA replication factor Cdt1 (CDT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [141]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosducin-like protein 3 (PDCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Benzatropine DMF7EXL Parkinsonian disorder Approved [252]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [307]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [308]
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Drug(s) Affected By Olfactory receptor 51B5 (OR51B5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
Drug(s) Affected By Calcium-binding protein 39-like (CAB39L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [285]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [309]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [310]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [274]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [311]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claspin (CLSPN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [103]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [74]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lymphoid-specific helicase (HELLS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FIGNL1-interacting regulator of recombination and mitosis (FIRRM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [263]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [221]
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Drug(s) Affected By Fanconi anemia group I protein (FANCI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [85]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2 and S phase-expressed protein 1 (GTSE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [312]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Placenta-specific gene 8 protein (PLAC8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Arsenic DMTL2Y1 N. A. N. A. Approved [313]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [89]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [314]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Clozapine DMFC71L Schizophrenia 6A20 Approved [315]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [221]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [259]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid-transporting ATPase VD (ATP10D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [316]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 7-dehydrocholesterol reductase (DHCR7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [317]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Fluoxetine DM3PD2C Bipolar depression Approved [254]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [208]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [251]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [145]
Clozapine DMFC71L Schizophrenia 6A20 Approved [315]
Menthol DMG2KW7 Back pain ME84.Z Approved [318]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transgelin-3 (TAGLN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [135]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [319]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [320]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell cycle progression protein 1 (CCPG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ampicillin DMHWE7P Acute epiglottitis Approved [76]
Bortezomib DMNO38U Leukemia Approved [321]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein timeless homolog (TIMELESS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transferrin receptor protein 2 (TFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Arsenic DMTL2Y1 N. A. N. A. Approved [322]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
KENPAULLONE DMAGVXW Discovery agent N.A. Patented [323]
Dorsomorphin DMKYXJW Discovery agent N.A. Investigative [323]
SU9516 DMQHG0R Discovery agent N.A. Investigative [323]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By DNA replication complex GINS protein PSF2 (GINS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptotic protease-activating factor 1 (APAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Methotrexate DM2TEOL Anterior urethra cancer Approved [207]
Quercetin DM3NC4M Obesity 5B81 Approved [175]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [324]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [325]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [326]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [327]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [328]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [329]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [330]
Gefitinib DM15F0X Colon adenocarcinoma Approved [331]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [332]
Selenium DM25CGV N. A. N. A. Approved [333]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [334]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [335]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [336]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RAF proto-oncogene serine/threonine-protein kinase (RAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [337]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [338]
Quercetin DM3NC4M Obesity 5B81 Approved [339]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [340]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [326]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [341]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Testosterone DM7HUNW Hot flushes GA30 Approved [343]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [344]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [183]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [346]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [347]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [348]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [349]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [350]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [351]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Gefitinib DM15F0X Colon adenocarcinoma Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [352]
Methotrexate DM2TEOL Anterior urethra cancer Approved [353]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [197]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [354]
Quercetin DM3NC4M Obesity 5B81 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurogenic locus notch homolog protein 1 (NOTCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [355]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [356]
Propranolol DM79NTF Angina pectoris BA40 Approved [357]
Testosterone DM7HUNW Hot flushes GA30 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [358]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [359]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Mebendazole DMO14SG Ascariasis 1F62 Approved [360]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein jagged-1 (JAG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [361]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [362]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [77]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [358]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [363]
Gefitinib DM15F0X Colon adenocarcinoma Approved [94]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [364]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [365]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [366]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [367]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [369]
Selenium DM25CGV N. A. N. A. Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [68]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [354]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [372]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurogenic locus notch homolog protein 2 (NOTCH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [373]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Clozapine DMFC71L Schizophrenia 6A20 Approved [315]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [358]
Bortezomib DMNO38U Leukemia Approved [204]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [374]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [263]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [375]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [376]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [96]
Selenium DM25CGV N. A. N. A. Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [377]
Methotrexate DM2TEOL Anterior urethra cancer Approved [207]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [378]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [379]
Quercetin DM3NC4M Obesity 5B81 Approved [142]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [380]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein jagged-2 (JAG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [381]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [262]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [358]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [382]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [267]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [383]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear migration protein nudC (NUDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [244]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [153]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [311]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Succinate--CoA ligase subunit beta, mitochondrial (SUCLG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [384]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [247]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Methotrexate DM2TEOL Anterior urethra cancer Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin, cytoplasmic 1 (ACTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Selenium DM25CGV N. A. N. A. Approved [153]
Etretinate DM2CZFA Keratosis ED56 Approved [385]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [386]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [76]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein P2 (RPLP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [262]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [387]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [388]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [389]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [268]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit alpha type-3 (PSMA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Menthol DMG2KW7 Back pain ME84.Z Approved [318]
Arsenic DMTL2Y1 N. A. N. A. Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [390]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [268]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock 70 kDa protein 4 (HSPA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [391]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [392]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Methotrexate DM2TEOL Anterior urethra cancer Approved [115]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [393]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [380]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 41 (FBXO41)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [316]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [233]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [286]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tropomyosin alpha-3 chain (TPM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [394]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Benzatropine DMF7EXL Parkinsonian disorder Approved [252]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [395]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [395]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [396]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [135]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein eS21 (RPS21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [397]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [398]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [286]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [399]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [400]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By 10 kDa heat shock protein, mitochondrial (HSPE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Quercetin DM3NC4M Obesity 5B81 Approved [401]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [184]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [402]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [184]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [388]
Folic Acid DMEMBJC Colorectal carcinoma Approved [403]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin light polypeptide 6 (MYL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [153]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [123]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [404]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [272]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit e, mitochondrial (ATP5ME)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Selenium DM25CGV N. A. N. A. Approved [153]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [245]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [384]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Indomethacin DMSC4A7 Bursitis Approved [405]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (SMARCE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [112]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit g, mitochondrial (ATP5MG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [245]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [406]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [407]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [408]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [286]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tropomyosin alpha-1 chain (TPM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Etretinate DM2CZFA Keratosis ED56 Approved [385]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Testosterone DM7HUNW Hot flushes GA30 Approved [84]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [406]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [328]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [247]
Bortezomib DMNO38U Leukemia Approved [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Splicing factor 3A subunit 3 (SF3A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [112]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [263]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [244]
PP-242 DM2348V Discovery agent N.A. Investigative [409]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [410]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Disintegrin and metalloproteinase domain-containing protein 7 (ADAM7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
[3H]methyltrienolone DMTSGOW Discovery agent N.A. Investigative [411]
Drug(s) Affected By Heat shock protein beta-1 (HSPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [412]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [413]
Selenium DM25CGV N. A. N. A. Approved [153]
Methotrexate DM2TEOL Anterior urethra cancer Approved [414]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [415]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [416]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diablo IAP-binding mitochondrial protein (DIABLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [412]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [96]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [417]
Quercetin DM3NC4M Obesity 5B81 Approved [418]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [419]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [420]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A10 (S100A10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [421]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [422]
Testosterone DM7HUNW Hot flushes GA30 Approved [109]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [109]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Folic Acid DMEMBJC Colorectal carcinoma Approved [423]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit beta, mitochondrial (ATP5F1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [363]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Etretinate DM2CZFA Keratosis ED56 Approved [385]
Quercetin DM3NC4M Obesity 5B81 Approved [424]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [367]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [384]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [249]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [367]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mirror-image polydactyly gene 1 protein (MIPOL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [126]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [263]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [147]
Urethane DM7NSI0 N. A. N. A. Phase 4 [258]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tropomyosin alpha-4 chain (TPM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [425]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ampicillin DMHWE7P Acute epiglottitis Approved [76]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [426]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein K (HNRNPK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [244]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [427]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [428]
Haloperidol DM96SE0 Delirium Approved [252]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [406]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [249]
Arsenic DMTL2Y1 N. A. N. A. Approved [429]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [428]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 alpha subcomplex subunit 2 (NDUFA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [430]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [273]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [431]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [286]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [432]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome b5 type B (CYB5B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [112]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [232]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ran-specific GTPase-activating protein (RANBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [251]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [433]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [433]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome regulatory subunit 6A (PSMC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Benzatropine DMF7EXL Parkinsonian disorder Approved [252]
Clozapine DMFC71L Schizophrenia 6A20 Approved [252]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein F (HNRNPF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [430]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [434]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [435]
ACYLINE DM9GRTK Prostate cancer 2C82.0 Phase 2 [436]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [268]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D54 (TPD52L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [437]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [430]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [127]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Arsenic DMTL2Y1 N. A. N. A. Approved [438]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [439]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pappalysin-1 (PAPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [242]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [129]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [86]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [133]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [247]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [440]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [441]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-15 (RAB15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [242]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [305]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [75]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [442]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [90]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [435]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock protein 105 kDa (HSPH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [380]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [281]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [83]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [443]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [402]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [2]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [3]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glutathione S-transferase alpha-1 (GSTA1) Main DME DE4ZHS1 GSTA1_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
10 kDa heat shock protein, mitochondrial (HSPE1) OT7JSZLB CH10_HUMAN Drug Response [6]
14-3-3 protein beta/alpha OTGBS3RF 1433B_HUMAN Drug Response [6]
14-3-3 protein epsilon OT3WQXNA 1433E_HUMAN Drug Response [6]
14-3-3 protein eta OTP8NJFJ 1433F_HUMAN Drug Response [6]
14-3-3 protein theta OTWG7F3H 1433T_HUMAN Drug Response [6]
14-3-3 protein zeta/delta OT2TKG9P 1433Z_HUMAN Drug Response [6]
26S proteasome regulatory subunit 6A (PSMC3) OTSKT0JI PRS6A_HUMAN Drug Response [6]
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) OTSMGKXQ EBP_HUMAN Gene/Protein Processing [7]
4-hydroxybenzoate polyprenyltransferase, mitochondrial (COQ2) OTDAKEY4 COQ2_HUMAN Gene/Protein Processing [7]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) OTLVN68B AAKB2_HUMAN Gene/Protein Processing [7]

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