Details of the Drug Combination

General Information of Drug Combination (ID: DC8H4IT)

• Drug Combination Name: Menadione + OZ277
• Indication: DD2; Status: Investigative [1]
• Component Drugs:
  Menadione (DMSJDTY): Small molecular drug
  OZ277 (DM1YB0R): Small molecular drug
• High-throughput Screening Result:
  Testing Cell Line: DD2
  Zero Interaction Potency (ZIP) Score: 4.909
  Bliss Independence Score: 5.14
  Loewe Additivity Score: 0.198
  LHighest Single Agent (HSA) Score: 4.677

Molecular Interaction Atlas of This Drug Combination

Indication(s) of Menadione

Disease Entry	ICD 11	Status	REF
Vitamin K deficiency	5B59	Approved	[2]
Prostate cancer	2C82.0	Phase 2	[3]

Menadione Interacts with 2 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Vasopressin V1 receptor (V1R)	TTPFZJ1	NOUNIPROTAC	Agonist	[10]
Aldehyde oxidase (AOX1)	TT3MOS2	AOXA_HUMAN	Inhibitor	[11]

Menadione Interacts with 1 DTP Molecule(s)

DTP Name	DTP ID	UniProt ID	Mode of Action	REF
Breast cancer resistance protein (ABCG2)	DTI7UX6	ABCG2_HUMAN	Substrate	[12]

Menadione Interacts with 10 DME Molecule(s)

DME Name	DME ID	UniProt ID	Mode of Action	REF
Cytochrome P450 1A2 (CYP1A2)	DEJGDUW	CP1A2_HUMAN	Metabolism	[13]
Cytochrome P450 1A1 (CYP1A1)	DE6OQ3W	CP1A1_HUMAN	Metabolism	[13]
Cytochrome P450 2E1 (CYP2E1)	DEVDYN7	CP2E1_HUMAN	Metabolism	[14]
NADPH-dependent carbonyl reductase 1 (CBR1)	DE9JFMC	CBR1_HUMAN	Metabolism	[15]
NADPH-dependent carbonyl reductase 3 (CBR3)	DEIVKZ8	CBR3_HUMAN	Metabolism	[16]
Methylenetetrahydrofolate reductase (MTHFR)	DEOXTPZ	MTHR_HUMAN	Metabolism	[17]
Methionine synthase reductase (MTRR)	DE6NIY9	MTRR_HUMAN	Metabolism	[18]
NADPH:quinone reductase (CRYZ)	DE8RYV5	QOR_HUMAN	Metabolism	[19]
Sepiapterin reductase (SPR)	DEJVDAT	SPRE_HUMAN	Metabolism	[20]
Nitroreductase (NTR)	DEPG9C0	A0A5K1UB29_SALTM	Metabolism	[21]

Menadione Interacts with 864 DOT Molecule(s)

DOT Name	DOT ID	UniProt ID	Mode of Action	REF
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)	OTW8V2V1	ABCG2_HUMAN	Affects Expression	[8]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12)	OTWICA51	PSD12_HUMAN	Increases Expression	[6]
CCN family member 1 (CCN1)	OTKJBEMD	CCN1_HUMAN	Increases Expression	[6]
Serine/threonine-protein kinase Chk1 (CHEK1)	OTTTI622	CHK1_HUMAN	Decreases Expression	[6]
Transcription factor MafG (MAFG)	OTBQFUZH	MAFG_HUMAN	Increases Expression	[6]
Adenylate cyclase type 3 (ADCY3)	OTGOQM6B	ADCY3_HUMAN	Decreases Expression	[6]
Target of Myb1 membrane trafficking protein (TOM1)	OT30QA56	TOM1_HUMAN	Increases Expression	[6]
Low-density lipoprotein receptor-related protein 6 (LRP6)	OTM7PSUR	LRP6_HUMAN	Increases Expression	[6]
Fibrinogen gamma chain (FGG)	OT5BJSEX	FIBG_HUMAN	Increases Expression	[6]
Ferritin light chain (FTL)	OTYQA8A6	FRIL_HUMAN	Increases Expression	[6]
Thymidine kinase, cytosolic (TK1)	OTY5JFM1	KITH_HUMAN	Decreases Expression	[6]
Transcription factor Jun (JUN)	OTCYBO6X	JUN_HUMAN	Increases Expression	[6]
Inhibin beta B chain (INHBB)	OT2QLD11	INHBB_HUMAN	Increases Expression	[6]
Metallothionein-1G (MT1G)	OTAV1OCR	MT1G_HUMAN	Increases Expression	[6]
Heat shock 70 kDa protein 6 (HSPA6)	OTH4S7WB	HSP76_HUMAN	Increases Expression	[6]
Glutathione peroxidase 2 (GPX2)	OTXI2NTI	GPX2_HUMAN	Increases Expression	[6]
NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)	OTPDCK1F	ADRO_HUMAN	Increases Expression	[6]
Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1)	OTGP6GA4	NR4A1_HUMAN	Increases Expression	[6]
Insulin-like growth factor-binding protein 5 (IGFBP5)	OTRE5V0C	IBP5_HUMAN	Increases Expression	[6]
Tumor necrosis factor receptor superfamily member 6 (FAS)	OTP9XG86	TNR6_HUMAN	Increases Expression	[6]
Protein S100-P (S100P)	OTJCXNJG	S100P_HUMAN	Increases Expression	[6]
DNA damage-inducible transcript 3 protein (DDIT3)	OTI8YKKE	DDIT3_HUMAN	Increases Expression	[6]
Serpin B5 (SERPINB5)	OTSMXQRJ	SPB5_HUMAN	Increases Expression	[6]
Cyclin-dependent kinase inhibitor 1 (CDKN1A)	OTQWHCZE	CDN1A_HUMAN	Increases Expression	[6]
Flap endonuclease 1 (FEN1)	OT6QGG7O	FEN1_HUMAN	Decreases Expression	[6]
Lamina-associated polypeptide 2, isoform alpha (TMPO)	OTL68EL4	LAP2A_HUMAN	Decreases Expression	[6]
Histone H3-like centromeric protein A (CENPA)	OT0NEJ4X	CENPA_HUMAN	Decreases Expression	[6]
Aldo-keto reductase family 1 member C2 (AKR1C2)	OTQ2XMO3	AK1C2_HUMAN	Increases Expression	[6]
Serine/threonine-protein kinase PLK1 (PLK1)	OTRZX45T	PLK1_HUMAN	Decreases Expression	[6]
Geranylgeranyl transferase type-1 subunit beta (PGGT1B)	OTNGYUXE	PGTB1_HUMAN	Increases Expression	[6]
DNA polymerase epsilon subunit 2 (POLE2)	OTAC9V6L	DPOE2_HUMAN	Decreases Expression	[6]
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB)	OT24GMCM	PP2AB_HUMAN	Increases Expression	[6]
Histone H4 (H4C1)	OTB71W46	H4_HUMAN	Decreases Expression	[6]
Protein BTG2 (BTG2)	OTZF6K1H	BTG2_HUMAN	Increases Expression	[6]
Metallothionein-1H (MT1H)	OT0MVBM6	MT1H_HUMAN	Increases Expression	[6]
Metallothionein-1X (MT1X)	OT9AKFVS	MT1X_HUMAN	Increases Expression	[6]
Signaling lymphocytic activation molecule (SLAMF1)	OTBTT3ZQ	SLAF1_HUMAN	Increases Expression	[6]
Delta(14)-sterol reductase LBR (LBR)	OT1HG3HG	LBR_HUMAN	Decreases Expression	[6]
ATP-dependent RNA helicase DDX42 (DDX42)	OT93XO40	DDX42_HUMAN	Increases Expression	[6]
Melanoma inhibitory activity protein 2 (MIA2)	OTOGTUTU	MIA2_HUMAN	Increases Expression	[6]
Oxidative stress-induced growth inhibitor 1 (OSGIN1)	OT9KIVZW	OSGI1_HUMAN	Increases Expression	[6]
Uncharacterized protein C17orf100 (C17ORF100)	OTHWVWC8	CQ100_HUMAN	Affects Expression	[7]
Kinetochore protein NDC80 homolog (NDC80)	OTS7D306	NDC80_HUMAN	Affects Expression	[7]
Transforming growth factor beta-1-induced transcript 1 protein (TGFB1I1)	OTIK337D	TGFI1_HUMAN	Affects Expression	[7]
Aldo-keto reductase family 1 member B10 (AKR1B10)	OTOA4HTH	AK1BA_HUMAN	Increases Expression	[7]
TSC22 domain family protein 2 (TSC22D2)	OTFXF349	T22D2_HUMAN	Affects Expression	[7]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)	OTL9I7LO	GA45B_HUMAN	Affects Expression	[7]
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5)	OTMVHF9E	LGR5_HUMAN	Affects Expression	[7]
Solute carrier family 22 member 3 (SLC22A3)	OTQYGVXX	S22A3_HUMAN	Affects Expression	[7]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3)	OTQ9ALTR	GCNT3_HUMAN	Increases Expression	[7]
Protein transport protein Sec24B (SEC24B)	OT6W8CWP	SC24B_HUMAN	Affects Expression	[7]
Caveolae-associated protein 2 (CAVIN2)	OTFHHDRU	CAVN2_HUMAN	Affects Expression	[7]
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Affects Expression	[7]
Calpain-2 catalytic subunit (CAPN2)	OTIAPE5J	CAN2_HUMAN	Affects Expression	[7]
Protein-lysine 6-oxidase (LOX)	OT1C2HIU	LYOX_HUMAN	Affects Expression	[7]
Large ribosomal subunit protein uL15 (RPL27A)	OTQQHPL0	RL27A_HUMAN	Affects Expression	[7]
Rap1 GTPase-activating protein 1 (RAP1GAP)	OTC31ONQ	RPGP1_HUMAN	Increases Expression	[7]
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PPP3CC)	OT0AQD93	PP2BC_HUMAN	Affects Expression	[7]
Regulator of G-protein signaling 3 (RGS3)	OTYG5OXI	RGS3_HUMAN	Affects Expression	[7]
Sulfite oxidase, mitochondrial (SUOX)	OTEJQ9FC	SUOX_HUMAN	Affects Expression	[7]
Nucleoside diphosphate-linked moiety X motif 6 (NUDT6)	OTCS3NYZ	NUDT6_HUMAN	Affects Expression	[7]
Ras-related protein R-Ras2 (RRAS2)	OT83NCEB	RRAS2_HUMAN	Increases Expression	[7]
Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1)	OTE0KX9F	GNAI1_HUMAN	Affects Expression	[7]
Arginase-2, mitochondrial (ARG2)	OTCPI0E8	ARGI2_HUMAN	Affects Expression	[7]
A-kinase anchor protein 12 (AKAP12)	OTCVRDDX	AKA12_HUMAN	Affects Expression	[7]
Prolow-density lipoprotein receptor-related protein 1 (LRP1)	OTHTEH4G	LRP1_HUMAN	Affects Expression	[7]
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)	OTG2T749	CP24A_HUMAN	Affects Expression	[7]
BMP and activin membrane-bound inhibitor homolog (BAMBI)	OTCEJ8W5	BAMBI_HUMAN	Affects Expression	[7]
Bcl-2-interacting killer (BIK)	OTTH1T3D	BIK_HUMAN	Increases Expression	[7]
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)	OT70Z4II	ADAM9_HUMAN	Affects Expression	[7]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)	OTXEE550	APR_HUMAN	Affects Expression	[7]
Kelch-like ECH-associated protein 1 (KEAP1)	OTFHOD0C	KEAP1_HUMAN	Decreases Expression	[7]
Nuclear receptor subfamily 0 group B member 2 (NR0B2)	OT7UVICX	NR0B2_HUMAN	Affects Expression	[7]
Transcriptional enhancer factor TEF-3 (TEAD4)	OTJS0T2B	TEAD4_HUMAN	Affects Expression	[7]
Myosin light chain kinase, smooth muscle (MYLK)	OT78QB4A	MYLK_HUMAN	Affects Expression	[7]
BTB/POZ domain-containing protein KCTD21 (KCTD21)	OTQT85SN	KCD21_HUMAN	Affects Expression	[7]
Glycerol-3-phosphate acyltransferase 3 (GPAT3)	OTJUGPK0	GPAT3_HUMAN	Increases Expression	[7]
Pleckstrin homology domain-containing family O member 1 (PLEKHO1)	OTMVUQ9W	PKHO1_HUMAN	Affects Expression	[7]
Mitochondrial amidoxime-reducing component 1 (MTARC1)	OTNBE033	MARC1_HUMAN	Affects Expression	[7]
Poly(A) RNA polymerase GLD2 (TENT2)	OTB7J28X	GLD2_HUMAN	Affects Expression	[7]
Apolipoprotein A-V (APOA5)	OTEVKLVA	APOA5_HUMAN	Affects Expression	[7]
Rapamycin-insensitive companion of mTOR (RICTOR)	OTCC58QJ	RICTR_HUMAN	Affects Expression	[7]
SH2 domain-containing protein 5 (SH2D5)	OTJDS1NN	SH2D5_HUMAN	Affects Expression	[7]
Suppressor APC domain-containing protein 2 (SAPCD2)	OTXS0EXM	SAPC2_HUMAN	Affects Expression	[7]
E3 ubiquitin-protein ligase SIAH1 (SIAH1)	OT29A838	SIAH1_HUMAN	Affects Expression	[7]
Spindle and kinetochore-associated protein 3 (SKA3)	OTLHEVJD	SKA3_HUMAN	Affects Expression	[7]
Adaptin ear-binding coat-associated protein 1 (NECAP1)	OTH49JRW	NECP1_HUMAN	Affects Expression	[7]
F-box only protein 30 (FBXO30)	OTD1P6LA	FBX30_HUMAN	Increases Expression	[7]
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5)	OTUM65JL	GDPD5_HUMAN	Affects Expression	[7]
Neuferricin (CYB5D2)	OTX10KKR	NEUFC_HUMAN	Affects Expression	[7]
Limb region 1 protein homolog (LMBR1)	OTGRQK9V	LMBR1_HUMAN	Affects Expression	[7]
Palladin (PALLD)	OTZ2MUJZ	PALLD_HUMAN	Affects Expression	[7]
Histone acetyltransferase KAT2A (KAT2A)	OTN0W2SW	KAT2A_HUMAN	Affects Expression	[7]
KiSS-1 receptor (KISS1R)	OTQA3J6G	KISSR_HUMAN	Affects Expression	[7]
Protein naked cuticle homolog 1 (NKD1)	OTY3MO97	NKD1_HUMAN	Affects Expression	[7]
60S ribosomal export protein NMD3 (NMD3)	OTXC5APO	NMD3_HUMAN	Affects Expression	[7]
Small integral membrane protein 19 (SMIM19)	OTFDI7JP	SMI19_HUMAN	Affects Expression	[7]
Protein Spindly (SPDL1)	OTI0JNTM	SPDLY_HUMAN	Affects Expression	[7]
Transcription cofactor HES-6 (HES6)	OTWO5SCF	HES6_HUMAN	Affects Expression	[7]
PRKC apoptosis WT1 regulator protein (PAWR)	OTKY7W52	PAWR_HUMAN	Affects Expression	[7]
Uncharacterized protein C8orf76 (C8ORF76)	OTINGL1Q	CH076_HUMAN	Affects Expression	[7]
Bile acid receptor (NR1H4)	OTWZLPTB	NR1H4_HUMAN	Affects Expression	[7]
Ran-binding protein 9 (RANBP9)	OTM8COM5	RANB9_HUMAN	Affects Expression	[7]
Dual specificity protein phosphatase 9 (DUSP9)	OTZZWEQL	DUS9_HUMAN	Affects Expression	[7]
Sulfiredoxin-1 (SRXN1)	OTYDBO4L	SRXN1_HUMAN	Increases Expression	[7]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1)	OTM3B3OA	TBL1R_HUMAN	Affects Expression	[7]
Protein sprouty homolog 4 (SPRY4)	OT2VK9N0	SPY4_HUMAN	Affects Expression	[7]
Uncharacterized protein C6orf62 (C6ORF62)	OTGK4G35	CF062_HUMAN	Affects Expression	[7]
Homeobox protein Hox-D1 (HOXD1)	OTN4V9ZF	HXD1_HUMAN	Affects Expression	[7]
Homeobox protein MIXL1 (MIXL1)	OT584VOQ	MIXL1_HUMAN	Affects Expression	[7]
Cdc42 effector protein 4 (CDC42EP4)	OTCPHZGJ	BORG4_HUMAN	Affects Expression	[7]
Receptor expression-enhancing protein 4 (REEP4)	OTJ8LZGQ	REEP4_HUMAN	Affects Expression	[7]
Ankyrin repeat family A protein 2 (ANKRA2)	OTLSLV5A	ANRA2_HUMAN	Affects Expression	[7]
Serine/threonine-protein kinase Sgk2 (SGK2)	OTCTVSHF	SGK2_HUMAN	Affects Expression	[7]
DNA polymerase delta subunit 4 (POLD4)	OTG578YH	DPOD4_HUMAN	Affects Expression	[7]
Kinesin-like protein KIF15 (KIF15)	OTJRJEXL	KIF15_HUMAN	Affects Expression	[7]
Structural maintenance of chromosomes protein 4 (SMC4)	OTEJE6AG	SMC4_HUMAN	Affects Expression	[7]
THAP domain-containing protein 1 (THAP1)	OTIWUSON	THAP1_HUMAN	Affects Expression	[7]
DNA damage-inducible transcript 4 protein (DDIT4)	OTHY8SY4	DDIT4_HUMAN	Affects Expression	[7]
REST corepressor 3 (RCOR3)	OT5LATME	RCOR3_HUMAN	Affects Expression	[7]
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (SLC6A14)	OTN51IPT	S6A14_HUMAN	Affects Expression	[7]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)	OTEU05TX	PPR3C_HUMAN	Affects Expression	[7]
Histone chaperone ASF1A (ASF1A)	OT4S44GP	ASF1A_HUMAN	Increases Expression	[7]
EMILIN-1 (EMILIN1)	OT94R6M1	EMIL1_HUMAN	Affects Expression	[7]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR)	OTTLD0KB	SQOR_HUMAN	Affects Expression	[7]
Extended synaptotagmin-2 (ESYT2)	OTWCXTX3	ESYT2_HUMAN	Affects Expression	[8]
Solute carrier family 22 member 23 (SLC22A23)	OT56BVY1	S22AN_HUMAN	Affects Expression	[8]
Fucose mutarotase (FUOM)	OTM201HH	FUCM_HUMAN	Affects Expression	[8]
Coiled-coil domain-containing protein 88B (CCDC88B)	OTEDUI2J	CC88B_HUMAN	Affects Expression	[8]
Galectin-8 (LGALS8)	OT71LJ8T	LEG8_HUMAN	Affects Expression	[8]
NF-kappa-B inhibitor epsilon (NFKBIE)	OTLAYEL9	IKBE_HUMAN	Affects Expression	[8]
Copper transport protein ATOX1 (ATOX1)	OT05LF59	ATOX1_HUMAN	Affects Expression	[8]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)	OTQ4W7MT	TR11B_HUMAN	Increases Expression	[22]
Nucleolar protein 56 (NOP56)	OTT67SRZ	NOP56_HUMAN	Affects Expression	[8]
Podocalyxin (PODXL)	OTPNQXF3	PODXL_HUMAN	Affects Expression	[8]
Transcription factor E2F3 (E2F3)	OT5VQMWY	E2F3_HUMAN	Affects Expression	[8]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PIK3C2B)	OTY2PROB	P3C2B_HUMAN	Affects Expression	[8]
Ectoderm-neural cortex protein 1 (ENC1)	OTJEUB6U	ENC1_HUMAN	Affects Expression	[8]
Putative transcription factor Ovo-like 1 (OVOL1)	OTFJ62UI	OVOL1_HUMAN	Affects Expression	[8]
Tumor necrosis factor ligand superfamily member 11 (TNFSF11)	OTJEPKEQ	TNF11_HUMAN	Decreases Expression	[22]
Krueppel-like factor 11 (KLF11)	OTKVQDJD	KLF11_HUMAN	Affects Expression	[8]
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23)	OTAAS85T	TIM23_HUMAN	Affects Expression	[8]
Long-chain fatty acid transport protein 2 (SLC27A2)	OT7JEG5F	S27A2_HUMAN	Affects Expression	[8]
Tectonin beta-propeller repeat-containing protein 2 (TECPR2)	OT1UFECZ	TCPR2_HUMAN	Affects Expression	[8]
NEDD4-binding protein 3 (N4BP3)	OTZW1RQS	N4BP3_HUMAN	Affects Expression	[8]
Period circadian protein homolog 2 (PER2)	OTU2B1DJ	PER2_HUMAN	Affects Expression	[8]
Guanine nucleotide exchange factor DBS (MCF2L)	OTEURA8N	MCF2L_HUMAN	Affects Expression	[8]
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C)	OT7DVQB0	RPAC1_HUMAN	Affects Expression	[8]
Dihydroxyacetone phosphate acyltransferase (GNPAT)	OTF6LWPO	GNPAT_HUMAN	Affects Expression	[8]
Laminin subunit alpha-5 (LAMA5)	OTIIXE4M	LAMA5_HUMAN	Affects Expression	[8]
Small ribosomal subunit protein uS12m (MRPS12)	OTGY4GIX	RT12_HUMAN	Affects Expression	[8]
Leptin receptor gene-related protein (LEPROT)	OT2EENVA	OBRG_HUMAN	Affects Expression	[8]
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT)	OT1Z1ZXE	OGT1_HUMAN	Affects Expression	[8]
High mobility group protein B3 (HMGB3)	OTCJ2EZY	HMGB3_HUMAN	Affects Expression	[8]
Baculoviral IAP repeat-containing protein 5 (BIRC5)	OTILXZYL	BIRC5_HUMAN	Affects Expression	[8]
ATP-binding cassette sub-family C member 3 (ABCC3)	OTC3IJV4	MRP3_HUMAN	Affects Expression	[8]
Claudin-3 (CLDN3)	OT71MN9S	CLD3_HUMAN	Affects Expression	[8]
Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4)	OTQKQ346	KCNN4_HUMAN	Affects Expression	[8]
Cytoplasmic dynein 1 light intermediate chain 2 (DYNC1LI2)	OTR7WJES	DC1L2_HUMAN	Affects Expression	[8]
Acidic fibroblast growth factor intracellular-binding protein (FIBP)	OTI7131S	FIBP_HUMAN	Affects Expression	[8]
Voltage-dependent T-type calcium channel subunit alpha-1G (CACNA1G)	OTGKBRE4	CAC1G_HUMAN	Affects Expression	[8]
Carbonic anhydrase 12 (CA12)	OT6WNFU8	CAH12_HUMAN	Affects Expression	[8]
Protein sprouty homolog 2 (SPRY2)	OTH0CRCZ	SPY2_HUMAN	Affects Expression	[8]
Tetraspanin-6 (TSPAN6)	OT8X0NWN	TSN6_HUMAN	Affects Expression	[8]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)	OT80DZMT	BUB1_HUMAN	Affects Expression	[8]
E3 ubiquitin ligase TRAF3IP2 (TRAF3IP2)	OTLLZERL	CIKS_HUMAN	Affects Expression	[8]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)	OTLVN68B	AAKB2_HUMAN	Affects Expression	[8]
Kinesin-like protein KIF1B (KIF1B)	OTI1XQTO	KIF1B_HUMAN	Affects Expression	[8]
HMG box-containing protein 1 (HBP1)	OTDPGGDV	HBP1_HUMAN	Affects Expression	[8]
Gasdermin-E (GSDME)	OT1ZWY32	GSDME_HUMAN	Affects Expression	[8]
Forkhead box protein D2 (FOXD2)	OTAF63YV	FOXD2_HUMAN	Affects Expression	[8]
Tetraspanin-3 (TSPAN3)	OT7WS6ZI	TSN3_HUMAN	Affects Expression	[8]
Catenin delta-1 (CTNND1)	OTUMPSHR	CTND1_HUMAN	Affects Expression	[8]
Dual specificity protein phosphatase CDC14B (CDC14B)	OTAESVOZ	CC14B_HUMAN	Affects Expression	[8]
H/ACA ribonucleoprotein complex subunit DKC1 (DKC1)	OTX7DJR6	DKC1_HUMAN	Affects Expression	[8]
Receptor activity-modifying protein 1 (RAMP1)	OT7UT2XB	RAMP1_HUMAN	Affects Expression	[8]
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7)	OTDNTHNR	ABCB7_HUMAN	Affects Expression	[8]
SLIT-ROBO Rho GTPase-activating protein 2 (SRGAP2)	OTUWFMCQ	SRGP2_HUMAN	Affects Expression	[8]
Frizzled-7 (FZD7)	OTTK3F6E	FZD7_HUMAN	Affects Expression	[8]
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2)	OTBT8KW9	NDUS2_HUMAN	Affects Expression	[8]
Cadherin-16 (CDH16)	OTR0GE9G	CAD16_HUMAN	Affects Expression	[8]
Breast carcinoma-amplified sequence 1 (BCAS1)	OTQKJR81	BCAS1_HUMAN	Affects Expression	[8]
Large ribosomal subunit protein bL33m (MRPL33)	OTA3YDH0	RM33_HUMAN	Affects Expression	[8]
Transforming acidic coiled-coil-containing protein 1 (TACC1)	OTGX20TE	TACC1_HUMAN	Affects Expression	[8]
Cell division control protein 45 homolog (CDC45)	OT6NNLOD	CDC45_HUMAN	Affects Expression	[8]
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1)	OTLMT95K	NDUB1_HUMAN	Affects Expression	[8]
Mitochondrial-processing peptidase subunit beta (PMPCB)	OTRMBHNM	MPPB_HUMAN	Affects Expression	[8]
Transcription factor Maf (MAF)	OT1GR3IZ	MAF_HUMAN	Affects Expression	[8]
Heat shock factor-binding protein 1 (HSBP1)	OTHZRMOF	HSBP1_HUMAN	Affects Expression	[8]
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200)	OTSAU864	U520_HUMAN	Affects Expression	[8]
Transient receptor potential cation channel subfamily A member 1 (TRPA1)	OTRDIR5M	TRPA1_HUMAN	Increases Activity	[23]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)	OTYG179K	PR15A_HUMAN	Affects Expression	[8]
Breast cancer anti-estrogen resistance protein 3 (BCAR3)	OTPJ17M8	BCAR3_HUMAN	Affects Expression	[8]
Ribonuclease P protein subunit p20 (POP7)	OTKC7SG5	POP7_HUMAN	Affects Expression	[8]
Eukaryotic translation initiation factor 3 subunit J (EIF3J)	OTJ4TAWK	EIF3J_HUMAN	Affects Expression	[8]
Lathosterol oxidase (SC5D)	OT41KMW4	SC5D_HUMAN	Affects Expression	[8]
Attractin (ATRN)	OTTCLOPV	ATRN_HUMAN	Affects Expression	[8]
Sterol O-acyltransferase 2 (SOAT2)	OTT0UXI3	SOAT2_HUMAN	Affects Expression	[8]
Delta(14)-sterol reductase TM7SF2 (TM7SF2)	OTILU5S7	ERG24_HUMAN	Affects Expression	[8]
Metastasis-associated protein MTA2 (MTA2)	OTCCYIQJ	MTA2_HUMAN	Affects Expression	[8]
Kelch repeat and BTB domain-containing protein 11 (KBTBD11)	OTBOY3WH	KBTBB_HUMAN	Affects Expression	[8]
monooxygenase MICAL2 (MICAL2)	OT04OQQJ	MICA2_HUMAN	Affects Expression	[8]
SAM and SH3 domain-containing protein 1 (SASH1)	OTQA8BD4	SASH1_HUMAN	Affects Expression	[8]
Glutaminase kidney isoform, mitochondrial (GLS)	OTGOZG2M	GLSK_HUMAN	Affects Expression	[8]
F-box only protein 21 (FBXO21)	OTM8L5VY	FBX21_HUMAN	Affects Expression	[8]
G2/mitotic-specific cyclin-B2 (CCNB2)	OTIEXTDK	CCNB2_HUMAN	Affects Expression	[8]
Epsin-2 (EPN2)	OTH5BHUN	EPN2_HUMAN	Affects Expression	[8]
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9)	OTGRFVKZ	FKBP9_HUMAN	Affects Expression	[8]
Bile salt export pump (ABCB11)	OTRU7THO	ABCBB_HUMAN	Decreases Expression	[24]
Transforming acidic coiled-coil-containing protein 2 (TACC2)	OTW4M7HI	TACC2_HUMAN	Affects Expression	[8]
Importin-7 (IPO7)	OTDFMQ00	IPO7_HUMAN	Affects Expression	[8]
Proteasome assembly chaperone 1 (PSMG1)	OTZ5I6UM	PSMG1_HUMAN	Affects Expression	[8]
Xylosyl- and glucuronyltransferase LARGE1 (LARGE1)	OTUH7H9F	LARG1_HUMAN	Affects Expression	[8]
Mitochondrial pyruvate carrier 2 (MPC2)	OT0GHXGG	MPC2_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase HERC2 (HERC2)	OTNQYKOB	HERC2_HUMAN	Affects Expression	[8]
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)	OTBMJUOC	M4K4_HUMAN	Affects Expression	[8]
Zinc finger protein SNAI1 (SNAI1)	OTDPYAMC	SNAI1_HUMAN	Decreases Expression	[5]
G patch domain and ankyrin repeat-containing protein 1 (GPANK1)	OT1TN2KT	GPAN1_HUMAN	Affects Expression	[8]
Anterior gradient protein 2 homolog (AGR2)	OTRRZT7W	AGR2_HUMAN	Affects Expression	[8]
Phosphoglycerate kinase 1 (PGK1)	OT6V1ICH	PGK1_HUMAN	Affects Expression	[8]
Serine protease inhibitor Kazal-type 1 (SPINK1)	OTSUVAL2	ISK1_HUMAN	Affects Expression	[8]
Alpha-2-macroglobulin (A2M)	OTFTX90K	A2MG_HUMAN	Affects Expression	[8]
Protein c-Fos (FOS)	OTJBUVWS	FOS_HUMAN	Increases Expression	[25]
Myc proto-oncogene protein (MYC)	OTPV5LUK	MYC_HUMAN	Decreases Expression	[26]
Collagen alpha-1(I) chain (COL1A1)	OTI31178	CO1A1_HUMAN	Decreases Expression	[22]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Affects Expression	[8]
Osteocalcin (BGLAP)	OTK1YLWQ	OSTCN_HUMAN	Decreases Expression	[22]
Ornithine aminotransferase, mitochondrial (OAT)	OTEKO8CT	OAT_HUMAN	Affects Expression	[8]
High affinity nerve growth factor receptor (NTRK1)	OTJORQAU	NTRK1_HUMAN	Increases Phosphorylation	[25]
Metallothionein-1E (MT1E)	OTXJKU4Y	MT1E_HUMAN	Affects Expression	[8]
Heat shock protein beta-1 (HSPB1)	OTHFZ8ED	HSPB1_HUMAN	Affects Expression	[8]
Histone H2A type 1-B/E (H2AC4)	OTMFQ662	H2A1B_HUMAN	Affects Expression	[8]
Aldehyde dehydrogenase, mitochondrial (ALDH2)	OTKJ9I3N	ALDH2_HUMAN	Affects Expression	[8]
ADP/ATP translocase 2 (SLC25A5)	OT1XIBMN	ADT2_HUMAN	Affects Expression	[8]
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA)	OTWJTCRK	PCCA_HUMAN	Affects Expression	[8]
Keratin, type II cytoskeletal 8 (KRT8)	OTTM4X11	K2C8_HUMAN	Increases Phosphorylation	[27]
Collagen alpha-2(V) chain (COL5A2)	OT5VOSQE	CO5A2_HUMAN	Affects Expression	[8]
Retinoblastoma-associated protein (RB1)	OTQJUJMZ	RB_HUMAN	Increases Expression	[28]
Protein S100-A6 (S100A6)	OTHHPZQ8	S10A6_HUMAN	Affects Expression	[8]
Acyl-CoA-binding protein (DBI)	OT884QY9	ACBP_HUMAN	Affects Expression	[8]
Metallothionein-1B (MT1B)	OTUA4FFH	MT1B_HUMAN	Affects Expression	[8]
Bifunctional glutamate/proline--tRNA ligase (EPRS1)	OTXK0FLB	SYEP_HUMAN	Affects Expression	[8]
Rho-related GTP-binding protein RhoC (RHOC)	OTOLE1FT	RHOC_HUMAN	Affects Expression	[8]
U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70)	OTP52YZ3	RU17_HUMAN	Affects Expression	[8]
Neuromedin-B (NMB)	OT4NLN6H	NMB_HUMAN	Affects Expression	[8]
P3 protein (SLC10A3)	OTUBZ4HT	P3_HUMAN	Affects Expression	[8]
HLA class I histocompatibility antigen, C alpha chain (HLA-C)	OTV38BUJ	HLAC_HUMAN	Affects Expression	[8]
Histone H1.4 (H1-4)	OTQ450A3	H14_HUMAN	Affects Expression	[8]
Laminin subunit gamma-1 (LAMC1)	OTIG527N	LAMC1_HUMAN	Affects Expression	[8]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)	OTA675TJ	GTR1_HUMAN	Affects Expression	[8]
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)	OTMKHVWC	C1TC_HUMAN	Affects Expression	[8]
Cation-independent mannose-6-phosphate receptor (IGF2R)	OTDXPQVX	MPRI_HUMAN	Affects Expression	[8]
Creatine kinase B-type (CKB)	OTUCKOTT	KCRB_HUMAN	Affects Expression	[8]
Cadherin-1 (CDH1)	OTFJMXPM	CADH1_HUMAN	Increases Expression	[5]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30)	OT9DERT1	GILT_HUMAN	Affects Expression	[8]
Keratin, type I cytoskeletal 10 (KRT10)	OTSVRD3Q	K1C10_HUMAN	Affects Expression	[8]
HLA class I histocompatibility antigen, alpha chain E (HLA-E)	OTX1CTFB	HLAE_HUMAN	Affects Expression	[8]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1)	OTNAZVKB	3BHS1_HUMAN	Affects Expression	[8]
Ezrin (EZR)	OTHBPF1Z	EZRI_HUMAN	Affects Expression	[8]
Metalloproteinase inhibitor 2 (TIMP2)	OT8S1RRP	TIMP2_HUMAN	Affects Expression	[8]
Histone H1.5 (H1-5)	OTAN7RD9	H15_HUMAN	Affects Expression	[8]
Receptor-type tyrosine-protein phosphatase alpha (PTPRA)	OTZA82J1	PTPRA_HUMAN	Affects Expression	[8]
Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6)	OTAFHAVI	ATF6A_HUMAN	Increases Expression	[29]
Peptidyl-glycine alpha-amidating monooxygenase (PAM)	OTX8HV5B	AMD_HUMAN	Affects Expression	[8]
Cadherin-2 (CDH2)	OTH0Y56P	CADH2_HUMAN	Decreases Expression	[5]
Guanine nucleotide-binding protein G(z) subunit alpha (GNAZ)	OTLTDTR8	GNAZ_HUMAN	Affects Expression	[8]
Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1)	OTODG57A	FUT1_HUMAN	Affects Expression	[8]
Transcription factor E3 (TFE3)	OTM99ZWH	TFE3_HUMAN	Affects Expression	[8]
Nuclear factor NF-kappa-B p105 subunit (NFKB1)	OTNRRD8I	NFKB1_HUMAN	Affects Expression	[8]
Histone H2A type 1-D (H2AC7)	OT3BAB16	H2A1D_HUMAN	Affects Expression	[8]
Lamin-B1 (LMNB1)	OT100T3P	LMNB1_HUMAN	Affects Expression	[8]
Receptor tyrosine-protein kinase erbB-3 (ERBB3)	OTRSST0A	ERBB3_HUMAN	Affects Expression	[8]
CD9 antigen (CD9)	OT2184XU	CD9_HUMAN	Affects Expression	[8]
Trifunctional purine biosynthetic protein adenosine-3 (GART)	OT01JWJB	PUR2_HUMAN	Affects Expression	[8]
Tenascin-X (TNXB)	OTVBWAV5	TENX_HUMAN	Affects Expression	[8]
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS)	OTMZN747	PUR6_HUMAN	Affects Expression	[8]
Galanin peptides (GAL)	OTB3VPTO	GALA_HUMAN	Affects Expression	[8]
Fibulin-1 (FBLN1)	OT5MHHOP	FBLN1_HUMAN	Affects Expression	[8]
Glycine dehydrogenase (GLDC)	OTVVDNW0	GCSP_HUMAN	Affects Expression	[8]
Histone H2B type 1-O (H2BC17)	OT8ED05P	H2B1O_HUMAN	Affects Expression	[8]
Eukaryotic translation initiation factor 4B (EIF4B)	OTE8TXA8	IF4B_HUMAN	Affects Expression	[8]
40-kDa huntingtin-associated protein (F8A1)	OTXTQ59R	HAP40_HUMAN	Affects Expression	[8]
Ribonucleoside-diphosphate reductase large subunit (RRM1)	OTXGQOR9	RIR1_HUMAN	Affects Expression	[8]
COUP transcription factor 2 (NR2F2)	OTJFS67N	COT2_HUMAN	Affects Expression	[8]
DNA replication licensing factor MCM3 (MCM3)	OTOOHQPM	MCM3_HUMAN	Affects Expression	[8]
DnaJ homolog subfamily B member 1 (DNAJB1)	OTCOSEVH	DNJB1_HUMAN	Affects Expression	[8]
Annexin A13 (ANXA13)	OTM33P73	ANX13_HUMAN	Affects Expression	[8]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Increases Phosphorylation	[30]
G0/G1 switch protein 2 (G0S2)	OT8FL49L	G0S2_HUMAN	Affects Expression	[8]
Replication protein A 70 kDa DNA-binding subunit (RPA1)	OT76POLP	RFA1_HUMAN	Affects Expression	[8]
Calnexin (CANX)	OTYP1F6J	CALX_HUMAN	Affects Expression	[8]
Protein ITPRID2 (ITPRID2)	OTO3JDX5	ITPI2_HUMAN	Affects Expression	[8]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Increases Phosphorylation	[30]
Receptor-type tyrosine-protein phosphatase mu (PTPRM)	OTCEL6PN	PTPRM_HUMAN	Affects Expression	[8]
CCN family member 2 (CCN2)	OTC39NSU	CCN2_HUMAN	Affects Expression	[8]
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1)	OTD13PJN	RBMS1_HUMAN	Affects Expression	[8]
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF)	OTRA8ZVE	PPIF_HUMAN	Affects Expression	[8]
CAP-Gly domain-containing linker protein 1 (CLIP1)	OTTGAEJE	CLIP1_HUMAN	Affects Expression	[8]
Sorcin (SRI)	OT4R3EAC	SORCN_HUMAN	Affects Expression	[8]
Leukocyte elastase inhibitor (SERPINB1)	OT5RDUFO	ILEU_HUMAN	Affects Expression	[8]
Rab GDP dissociation inhibitor alpha (GDI1)	OTYM3928	GDIA_HUMAN	Affects Expression	[8]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)	OTCMMMIZ	3HIDH_HUMAN	Affects Expression	[8]
Bifunctional purine biosynthesis protein ATIC (ATIC)	OT8XE052	PUR9_HUMAN	Affects Expression	[8]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)	OTB06ESI	ACSL1_HUMAN	Affects Expression	[8]
Histone H2B type 1-B (H2BC3)	OT1BLFJO	H2B1B_HUMAN	Affects Expression	[8]
DNA replication licensing factor MCM5 (MCM5)	OTAHLB62	MCM5_HUMAN	Affects Expression	[8]
Catenin beta-1 (CTNNB1)	OTZ932A3	CTNB1_HUMAN	Decreases Expression	[5]
Merlin (NF2)	OT6E5ACG	MERL_HUMAN	Affects Expression	[8]
Replication factor C subunit 4 (RFC4)	OTWALD2R	RFC4_HUMAN	Affects Expression	[8]
Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)	OTNWEJ5Y	PCKGC_HUMAN	Affects Expression	[8]
Lon protease homolog, mitochondrial (LONP1)	OT665WYT	LONM_HUMAN	Affects Expression	[8]
RNA-binding motif protein, X chromosome (RBMX)	OTFZN66E	RBMX_HUMAN	Affects Expression	[8]
DNA-binding protein inhibitor ID-1 (ID1)	OTKGNZN5	ID1_HUMAN	Affects Expression	[8]
Isoleucine--tRNA ligase, cytoplasmic (IARS1)	OT9WXH5N	SYIC_HUMAN	Affects Expression	[8]
Cyclin-dependent kinase inhibitor 2A (CDKN2A)	OTN0ZWAE	CDN2A_HUMAN	Increases Expression	[28]
Ran-specific GTPase-activating protein (RANBP1)	OTQE226K	RANG_HUMAN	Affects Expression	[8]
Peptidyl-prolyl cis-trans isomerase C (PPIC)	OTY5Q42N	PPIC_HUMAN	Affects Expression	[8]
Mitogen-activated protein kinase 8 (MAPK8)	OTEREYS5	MK08_HUMAN	Increases Activity	[31]
ATP synthase subunit O, mitochondrial (ATP5PO)	OTU3MCTN	ATPO_HUMAN	Affects Expression	[8]
T-complex protein 1 subunit epsilon (CCT5)	OTPZ38BT	TCPE_HUMAN	Affects Expression	[8]
Centromere protein F (CENPF)	OT7AG0SW	CENPF_HUMAN	Affects Expression	[8]
Histidine--tRNA ligase, mitochondrial (HARS2)	OTC8X3H9	SYHM_HUMAN	Affects Expression	[8]
CCAAT/enhancer-binding protein alpha (CEBPA)	OTOM9OE4	CEBPA_HUMAN	Affects Expression	[8]
Proteasome subunit beta type-3 (PSMB3)	OTVBON40	PSB3_HUMAN	Affects Expression	[8]
Transmembrane emp24 domain-containing protein 10 (TMED10)	OTUXSHH7	TMEDA_HUMAN	Affects Expression	[8]
Protein numb homolog (NUMB)	OTMB586Q	NUMB_HUMAN	Decreases Expression	[32]
Selenoprotein P (SELENOP)	OT02B8IR	SEPP1_HUMAN	Affects Expression	[8]
Cyclin-dependent kinase inhibitor 1C (CDKN1C)	OTASTJ3Q	CDN1C_HUMAN	Affects Expression	[8]
Cysteine-rich protein 1 (CRIP1)	OT0EICG3	CRIP1_HUMAN	Affects Expression	[8]
Rab GDP dissociation inhibitor beta (GDI2)	OTGLY3I7	GDIB_HUMAN	Affects Expression	[8]
Sulfate transporter (SLC26A2)	OTJNHNTO	S26A2_HUMAN	Affects Expression	[8]
Biotin--protein ligase (HLCS)	OTPDUX30	BPL1_HUMAN	Affects Expression	[8]
Ras-related protein Rab-5C (RAB5C)	OTQE5QQ2	RAB5C_HUMAN	Affects Expression	[8]
Dual specificity protein phosphatase 3 (DUSP3)	OTPJX9B4	DUS3_HUMAN	Affects Expression	[8]
Cyclin-G1 (CCNG1)	OT17IA9L	CCNG1_HUMAN	Affects Expression	[8]
Tyrosine-protein kinase JAK3 (JAK3)	OTQ8QW2L	JAK3_HUMAN	Increases Phosphorylation	[33]
DNA mismatch repair protein Msh6 (MSH6)	OT46FP09	MSH6_HUMAN	Affects Expression	[8]
Holocytochrome c-type synthase (HCCS)	OTQE88BE	CCHL_HUMAN	Affects Expression	[8]
Mitogen-activated protein kinase 10 (MAPK10)	OTC46VX1	MK10_HUMAN	Decreases Activity	[34]
Calcipressin-1 (RCAN1)	OT1MVXC7	RCAN1_HUMAN	Increases Phosphorylation	[35]
Ornithine decarboxylase antizyme 1 (OAZ1)	OTPT0PKZ	OAZ1_HUMAN	Affects Expression	[8]
UV excision repair protein RAD23 homolog B (RAD23B)	OT0PGOG3	RD23B_HUMAN	Affects Expression	[8]
Epithelial membrane protein 2 (EMP2)	OTPS2H0L	EMP2_HUMAN	Affects Expression	[8]
Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2)	OTC3RUN9	HMCS2_HUMAN	Affects Expression	[8]
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)	OT6W40XU	P5CS_HUMAN	Affects Expression	[8]
Laminin subunit beta-2 (LAMB2)	OT71OI2Y	LAMB2_HUMAN	Affects Expression	[8]
Hepatocyte nuclear factor 3-alpha (FOXA1)	OTEBY0TD	FOXA1_HUMAN	Affects Expression	[8]
Hepatocyte nuclear factor 3-gamma (FOXA3)	OTRGT2OT	FOXA3_HUMAN	Affects Expression	[8]
C-terminal-binding protein 2 (CTBP2)	OTGZGT87	CTBP2_HUMAN	Affects Expression	[8]
Serine/threonine-protein kinase SIK1 (SIK1)	OT6FCHME	SIK1_HUMAN	Affects Expression	[8]
SCAN domain-containing protein 1 (SCAND1)	OTRG0AGH	SCND1_HUMAN	Affects Expression	[8]
Nuclear pore complex protein Nup107 (NUP107)	OTG4RDYS	NU107_HUMAN	Affects Expression	[8]
Transcription elongation factor 1 homolog (ELOF1)	OT8BXS5U	ELOF1_HUMAN	Affects Expression	[8]
Beta-defensin 1 (DEFB1)	OT5SV0E4	DEFB1_HUMAN	Affects Expression	[8]
Protein transport protein Sec61 subunit gamma (SEC61G)	OT7MJRXY	SC61G_HUMAN	Affects Expression	[8]
Myosin light polypeptide 6 (MYL6)	OT84YKPM	MYL6_HUMAN	Affects Expression	[8]
Eukaryotic initiation factor 4A-I (EIF4A1)	OTMTBX6N	IF4A1_HUMAN	Affects Expression	[8]
Proteasome subunit alpha type-6 (PSMA6)	OTJ6RPX5	PSA6_HUMAN	Affects Expression	[8]
Cyclin-dependent kinases regulatory subunit 1 (CKS1B)	OTNUPLUJ	CKS1_HUMAN	Affects Expression	[8]
Tetraspanin-5 (TSPAN5)	OTHCCHHV	TSN5_HUMAN	Affects Expression	[8]
Small nuclear ribonucleoprotein Sm D1 (SNRPD1)	OTWKZV4E	SMD1_HUMAN	Affects Expression	[8]
Histone H2B type 1-C/E/F/G/I (H2BC10)	OTLQH0D6	H2B1C_HUMAN	Affects Expression	[8]
Small ribosomal subunit protein RACK1 (RACK1)	OTZBCQ1U	RACK1_HUMAN	Affects Expression	[8]
Selenoprotein W (SELENOW)	OTVSKPAN	SELW_HUMAN	Affects Expression	[8]
Histone H3.1 (H3C1)	OTGBGOZW	H31_HUMAN	Affects Expression	[8]
Hemoglobin subunit alpha (HBA1)	OTW2BQF4	HBA_HUMAN	Affects Expression	[8]
Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA)	OT2CEYTT	SHPS1_HUMAN	Affects Expression	[8]
Phosphoserine phosphatase (PSPH)	OTV1PVAX	SERB_HUMAN	Affects Expression	[8]
Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2)	OTEO98CR	IF4G2_HUMAN	Affects Expression	[8]
General transcription factor II-I (GTF2I)	OTUYL1TQ	GTF2I_HUMAN	Affects Expression	[8]
T-complex protein 1 subunit beta (CCT2)	OTW1VV4E	TCPB_HUMAN	Affects Expression	[8]
Iroquois-class homeodomain protein IRX-5 (IRX5)	OT05J514	IRX5_HUMAN	Affects Expression	[8]
Protein jagged-1 (JAG1)	OT3LGT6K	JAG1_HUMAN	Affects Expression	[8]
Solute carrier family 25 member 3 (SLC25A3)	OTAWGR4K	S25A3_HUMAN	Affects Expression	[8]
Heat shock factor protein 1 (HSF1)	OTYNJ4KP	HSF1_HUMAN	Increases Activity	[36]
Transcription factor E2F1 (E2F1)	OTLKYBBC	E2F1_HUMAN	Affects Expression	[8]
Transcription factor RelB (RELB)	OTU3QYEF	RELB_HUMAN	Affects Expression	[8]
Melanocyte-stimulating hormone receptor (MC1R)	OTB95LIK	MSHR_HUMAN	Affects Expression	[8]
Exosome complex component 10 (EXOSC10)	OTH8Z0AL	EXOSX_HUMAN	Affects Expression	[8]
Kinesin-like protein KIF23 (KIF23)	OTY850JC	KIF23_HUMAN	Affects Expression	[8]
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase , mitochondrial (ALDH6A1)	OT8LCZCT	MMSA_HUMAN	Affects Expression	[8]
Rod outer segment membrane protein 1 (ROM1)	OTE7H0YV	ROM1_HUMAN	Affects Expression	[8]
AT-rich interactive domain-containing protein 5A (ARID5A)	OTQT7CG9	ARI5A_HUMAN	Affects Expression	[8]
Aldo-keto reductase family 1 member C1 (AKR1C1)	OTQKR4CM	AK1C1_HUMAN	Affects Expression	[8]
Max dimerization protein 1 (MXD1)	OTS5CTHX	MAD1_HUMAN	Affects Expression	[8]
Serine/arginine-rich splicing factor 11 (SRSF11)	OTZSV6CZ	SRS11_HUMAN	Affects Expression	[8]
Dual specificity protein phosphatase 2 (DUSP2)	OTH54FMR	DUS2_HUMAN	Affects Expression	[8]
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11)	OTFH9M73	PTN11_HUMAN	Affects Expression	[8]
Amyloid beta precursor like protein 2 (APLP2)	OTTFE53M	APLP2_HUMAN	Affects Expression	[8]
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP)	OTPYQX3K	C1QBP_HUMAN	Affects Expression	[8]
Tight junction protein ZO-1 (TJP1)	OTBDCUPK	ZO1_HUMAN	Increases Expression	[5]
Trefoil factor 3 (TFF3)	OTJJDRTU	TFF3_HUMAN	Affects Expression	[8]
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1)	OT5GO2PL	KHDR1_HUMAN	Affects Expression	[8]
ATP-dependent RNA helicase A (DHX9)	OT5AAOQI	DHX9_HUMAN	Affects Expression	[8]
Sodium-dependent phosphate transporter 2 (SLC20A2)	OT6E2DAX	S20A2_HUMAN	Affects Expression	[8]
Golgin subfamily A member 3 (GOLGA3)	OT27354E	GOGA3_HUMAN	Affects Expression	[8]
Pseudouridine-5'-phosphatase (PUDP)	OTEPEJLX	HDHD1_HUMAN	Affects Expression	[8]
Protein mab-21-like 4 (MAB21L4)	OT4FRKXR	MB214_HUMAN	Affects Expression	[8]
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2)	OTZCNM33	NSUN2_HUMAN	Affects Expression	[8]
Cingulin-like protein 1 (CGNL1)	OTRE9DGT	CGNL1_HUMAN	Affects Expression	[8]
Nuclear pore complex protein Nup160 (NUP160)	OTUKVV3I	NU160_HUMAN	Affects Expression	[8]
Sterol regulatory element-binding protein cleavage-activating protein (SCAP)	OTCVXOD6	SCAP_HUMAN	Affects Expression	[8]
Tripartite motif-containing protein 26 (TRIM26)	OTS0DJIP	TRI26_HUMAN	Affects Expression	[8]
Interleukin enhancer-binding factor 2 (ILF2)	OTWWVM9X	ILF2_HUMAN	Affects Expression	[8]
Ankyrin-3 (ANK3)	OTJ3IRBP	ANK3_HUMAN	Affects Expression	[8]
Active breakpoint cluster region-related protein (ABR)	OTZQK8JF	ABR_HUMAN	Affects Expression	[8]
GATOR1 complex protein NPRL3 (NPRL3)	OTS4HE8E	NPRL3_HUMAN	Affects Expression	[8]
Krueppel-like factor 10 (KLF10)	OT4F4UGS	KLF10_HUMAN	Affects Expression	[8]
T-box transcription factor TBX2 (TBX2)	OTTOT7A9	TBX2_HUMAN	Affects Expression	[8]
Alpha-1-syntrophin (SNTA1)	OTUICTGZ	SNTA1_HUMAN	Affects Expression	[8]
Treacle protein (TCOF1)	OT4BOYTM	TCOF_HUMAN	Affects Expression	[8]
NGFI-A-binding protein 1 (NAB1)	OTEWHIZR	NAB1_HUMAN	Affects Expression	[8]
Interferon regulatory factor 5 (IRF5)	OT8SIIAP	IRF5_HUMAN	Affects Expression	[8]
Cullin-4A (CUL4A)	OTTBV70J	CUL4A_HUMAN	Affects Expression	[8]
Mannosyl-oligosaccharide glucosidase (MOGS)	OT99MBGB	MOGS_HUMAN	Affects Expression	[8]
Methylglutaconyl-CoA hydratase, mitochondrial (AUH)	OT8VKBXX	AUHM_HUMAN	Affects Expression	[8]
Beta-1-syntrophin (SNTB1)	OTSRBECI	SNTB1_HUMAN	Affects Expression	[8]
Core-binding factor subunit beta (CBFB)	OTIAC6W4	PEBB_HUMAN	Affects Expression	[8]
Cytoskeleton-associated protein 5 (CKAP5)	OTEMFY7X	CKAP5_HUMAN	Affects Expression	[8]
Cyclin-I (CCNI)	OT8863O1	CCNI_HUMAN	Affects Expression	[8]
Tripartite motif-containing protein 14 (TRIM14)	OTLQKUG0	TRI14_HUMAN	Affects Expression	[8]
Rho guanine nucleotide exchange factor 7 (ARHGEF7)	OT9BPJCL	ARHG7_HUMAN	Affects Expression	[8]
Four and a half LIM domains protein 2 (FHL2)	OT0OAYWT	FHL2_HUMAN	Affects Expression	[8]
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1)	OTD1KRKO	DYHC1_HUMAN	Affects Expression	[8]
Transcription factor HES-1 (HES1)	OT8P19W2	HES1_HUMAN	Increases Expression	[32]
Histone RNA hairpin-binding protein (SLBP)	OTVYYQRT	SLBP_HUMAN	Affects Expression	[8]
Protein disulfide-isomerase A5 (PDIA5)	OT76ZSX5	PDIA5_HUMAN	Affects Expression	[8]
Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3)	OTGQ2AOJ	ITPR3_HUMAN	Affects Expression	[8]
Mediator of DNA damage checkpoint protein 1 (MDC1)	OTEUQH4J	MDC1_HUMAN	Affects Expression	[8]
KN motif and ankyrin repeat domain-containing protein 1 (KANK1)	OT2E7A6W	KANK1_HUMAN	Affects Expression	[8]
Structural maintenance of chromosomes protein 1A (SMC1A)	OT9ZMRK9	SMC1A_HUMAN	Affects Expression	[8]
Ribosome biogenesis protein BMS1 homolog (BMS1)	OTEGQ8ZO	BMS1_HUMAN	Affects Expression	[8]
Importin subunit beta-1 (KPNB1)	OTBT2HFL	IMB1_HUMAN	Affects Expression	[8]
Nucleolar and coiled-body phosphoprotein 1 (NOLC1)	OTKDZU0D	NOLC1_HUMAN	Affects Expression	[8]
Condensin complex subunit 2 (NCAPH)	OTXOS97C	CND2_HUMAN	Affects Expression	[8]
PCNA-associated factor (PCLAF)	OTMVIOUU	PAF15_HUMAN	Affects Expression	[8]
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1)	OT9EROL6	HERP1_HUMAN	Affects Expression	[8]
Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1)	OT4DQ8F2	RB3GP_HUMAN	Affects Expression	[8]
Metal cation symporter ZIP14 (SLC39A14)	OTGR686L	S39AE_HUMAN	Affects Expression	[8]
Reticulocalbin-1 (RCN1)	OT3JBGAG	RCN1_HUMAN	Affects Expression	[8]
Poly(rC)-binding protein 1 (PCBP1)	OTHN0TD7	PCBP1_HUMAN	Affects Expression	[8]
Pumilio homolog 3 (PUM3)	OTN1IPNS	PUM3_HUMAN	Affects Expression	[8]
Disks large-associated protein 5 (DLGAP5)	OTWCN39U	DLGP5_HUMAN	Affects Expression	[8]
Monocyte to macrophage differentiation factor (MMD)	OTB5I4OC	PAQRB_HUMAN	Affects Expression	[8]
Dual specificity testis-specific protein kinase 1 (TESK1)	OT42FF0Z	TESK1_HUMAN	Affects Expression	[8]
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD)	OTBOSJHO	TRADD_HUMAN	Affects Expression	[8]
Bcl-2 homologous antagonist/killer (BAK1)	OTDP6ILW	BAK_HUMAN	Affects Expression	[8]
Diacylglycerol kinase delta (DGKD)	OTNI8HAH	DGKD_HUMAN	Affects Expression	[8]
Thiosulfate sulfurtransferase (TST)	OTZ4F5LK	THTR_HUMAN	Affects Expression	[8]
Histone H2A type 2-C (H2AC20)	OTEIVLM1	H2A2C_HUMAN	Affects Expression	[8]
Dual specificity protein phosphatase 6 (DUSP6)	OT4H6RKW	DUS6_HUMAN	Affects Expression	[8]
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH)	OTJDOL20	HCDH_HUMAN	Affects Expression	[8]
GON-4-like protein (GON4L)	OTWQVLO9	GON4L_HUMAN	Affects Expression	[8]
Membrane protein FAM174B (FAM174B)	OT1SCOTY	F174B_HUMAN	Affects Expression	[8]
Programmed cell death protein 4 (PDCD4)	OTZ6NXUX	PDCD4_HUMAN	Affects Expression	[8]
ORM1-like protein 2 (ORMDL2)	OT2N1MW0	ORML2_HUMAN	Affects Expression	[8]
Pleckstrin homology-like domain family A member 2 (PHLDA2)	OTMV9DPP	PHLA2_HUMAN	Affects Expression	[8]
Transmembrane protein 177 (TMEM177)	OT3KLW01	TM177_HUMAN	Affects Expression	[8]
TPA-induced transmembrane protein (C3ORF52)	OTI0JAT8	TTMP_HUMAN	Affects Expression	[8]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1)	OTGFK4MH	NHRF3_HUMAN	Affects Expression	[8]
Protein O-mannosyl-transferase TMTC4 (TMTC4)	OTC4TDHU	TMTC4_HUMAN	Affects Expression	[8]
Protein phosphatase 1 regulatory subunit 26 (PPP1R26)	OTAKR0DQ	PPR26_HUMAN	Affects Expression	[8]
SH3 and PX domain-containing protein 2A (SH3PXD2A)	OTYRQJIH	SPD2A_HUMAN	Affects Expression	[8]
Lengsin (LGSN)	OTQG5Z82	LGSN_HUMAN	Affects Expression	[8]
Divergent protein kinase domain 1B (DIPK1B)	OTSPU5O5	DIK1B_HUMAN	Affects Expression	[8]
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PPRC1)	OT6GB3WR	PPRC1_HUMAN	Affects Expression	[8]
Focadhesin (FOCAD)	OT83QOSI	FOCAD_HUMAN	Affects Expression	[8]
Immediate early response gene 5 protein (IER5)	OTJPTXMD	IER5_HUMAN	Affects Expression	[8]
Proteasome adapter and scaffold protein ECM29 (ECPAS)	OT1C0KOI	ECM29_HUMAN	Affects Expression	[8]
La-related protein 1B (LARP1B)	OT9JZ7K5	LAR1B_HUMAN	Affects Expression	[8]
TBC1 domain family member 9B (TBC1D9B)	OTV5UGNC	TBC9B_HUMAN	Affects Expression	[8]
Heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT)	OTXPCELL	HGNAT_HUMAN	Affects Expression	[8]
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1)	OTG14TPO	GL8D1_HUMAN	Affects Expression	[8]
Ankyrin repeat and SAM domain-containing protein 6 (ANKS6)	OT6DXD3Q	ANKS6_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase RNF43 (RNF43)	OT2R9YDP	RNF43_HUMAN	Affects Expression	[8]
Transmembrane protein 42 (TMEM42)	OTCG6EZ0	TMM42_HUMAN	Affects Expression	[8]
Transcription factor Sp5 (SP5)	OT4HUP9B	SP5_HUMAN	Affects Expression	[8]
Histone H2A type 2-A (H2AC18)	OTCE5JC7	H2A2A_HUMAN	Affects Expression	[8]
Retrotransposon Gag-like protein 6 (RTL6)	OT9LG762	RTL6_HUMAN	Affects Expression	[8]
Molybdate-anion transporter (MFSD5)	OTB1C4DJ	MFSD5_HUMAN	Affects Expression	[8]
Volume-regulated anion channel subunit LRRC8E (LRRC8E)	OTUZTANF	LRC8E_HUMAN	Affects Expression	[8]
Homeobox-containing protein 1 (HMBOX1)	OTPKTBVI	HMBX1_HUMAN	Affects Expression	[8]
MRN complex-interacting protein (MRNIP)	OTIEU9NH	MRNIP_HUMAN	Affects Expression	[8]
Epithelial splicing regulatory protein 1 (ESRP1)	OTNCS4SL	ESRP1_HUMAN	Affects Expression	[8]
Endogenous Bornavirus-like nucleoprotein 2 (EBLN2)	OTSZ86MP	EBLN2_HUMAN	Affects Expression	[8]
Phospholipase B-like 1 (PLBD1)	OTHYEB4W	PLBL1_HUMAN	Affects Expression	[8]
Pyridoxal-dependent decarboxylase domain-containing protein 1 (PDXDC1)	OTKH7U5Q	PDXD1_HUMAN	Affects Expression	[8]
RNA polymerase-associated protein CTR9 homolog (CTR9)	OTP151PZ	CTR9_HUMAN	Affects Expression	[8]
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 (OGFOD3)	OT3TAYTX	OGFD3_HUMAN	Affects Expression	[8]
Ras-like protein family member 11A (RASL11A)	OTDO6CMY	RSLBA_HUMAN	Affects Expression	[8]
Ankyrin repeat domain-containing protein 11 (ANKRD11)	OTV0V70M	ANR11_HUMAN	Affects Expression	[8]
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1)	OTF91GTL	FIP1_HUMAN	Affects Expression	[8]
Sushi domain-containing protein 1 (SUSD1)	OTR3UGLY	SUSD1_HUMAN	Affects Expression	[8]
Rab11 family-interacting protein 1 (RAB11FIP1)	OT0T71OW	RFIP1_HUMAN	Affects Expression	[8]
DnaJ homolog subfamily C member 14 (DNAJC14)	OT7DPIVN	DJC14_HUMAN	Affects Expression	[8]
GRB10-interacting GYF protein 2 (GIGYF2)	OTFNVEJ4	GGYF2_HUMAN	Affects Expression	[8]
Nesprin-3 (SYNE3)	OTEOJBYB	SYNE3_HUMAN	Affects Expression	[8]
Uncharacterized protein C15orf39 (C15ORF39)	OTSVIW9K	CO039_HUMAN	Affects Expression	[8]
PAX-interacting protein 1 (PAXIP1)	OTRHTKG3	PAXI1_HUMAN	Affects Expression	[8]
RING finger protein 44 (RNF44)	OTGWL4U4	RNF44_HUMAN	Affects Expression	[8]
Mitochondrial enolase superfamily member 1 (ENOSF1)	OT65D3ZK	ENOF1_HUMAN	Affects Expression	[8]
Histone H2A type 3 (H2AC25)	OTPO62JI	H2A3_HUMAN	Affects Expression	[8]
Lysine-specific demethylase 3B (KDM3B)	OTZU5J5S	KDM3B_HUMAN	Affects Expression	[8]
CXXC-type zinc finger protein 5 (CXXC5)	OTGCN3B5	CXXC5_HUMAN	Affects Expression	[8]
Glutathione S-transferase A5 (GSTA5)	OTG7ID8U	GSTA5_HUMAN	Affects Expression	[8]
Retinoic acid-induced protein 1 (RAI1)	OTKLQU00	RAI1_HUMAN	Affects Expression	[8]
Interferon regulatory factor 2-binding protein 2 (IRF2BP2)	OTSSRRCA	I2BP2_HUMAN	Affects Expression	[8]
Neuroepithelial cell-transforming gene 1 protein (NET1)	OTZHNMJV	ARHG8_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase RBBP6 (RBBP6)	OTTVG4HU	RBBP6_HUMAN	Affects Expression	[8]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1)	OTKCR5XL	CK2N1_HUMAN	Affects Expression	[8]
Small integral membrane protein 29 (SMIM29)	OTI2IF40	SIM29_HUMAN	Affects Expression	[8]
B-cell CLL/lymphoma 9-like protein (BCL9L)	OTTWI90E	BCL9L_HUMAN	Decreases Expression	[5]
THO complex subunit 4 (ALYREF)	OTOF2ADD	THOC4_HUMAN	Affects Expression	[8]
Glucocorticoid-induced transcript 1 protein (GLCCI1)	OTU0R1CU	GLCI1_HUMAN	Affects Expression	[8]
Probable D-lactate dehydrogenase, mitochondrial (LDHD)	OTTKLJWP	LDHD_HUMAN	Affects Expression	[8]
Cytochrome c oxidase assembly factor 5 (COA5)	OTK12EG7	COA5_HUMAN	Affects Expression	[8]
F-box only protein 11 (FBXO11)	OTGWF3Q2	FBX11_HUMAN	Affects Expression	[8]
RNA-binding protein MEX3D (MEX3D)	OTAUWRK7	MEX3D_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase RNF130 (RNF130)	OT7DWTFH	GOLI_HUMAN	Affects Expression	[8]
Peptidyl-tRNA hydrolase (PTRH1)	OTOAOS93	PTH_HUMAN	Affects Expression	[8]
Podoplanin (PDPN)	OTBUV19I	PDPN_HUMAN	Increases Expression	[22]
Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPARGC1B)	OTN6FKCB	PRGC2_HUMAN	Affects Expression	[8]
Rab11 family-interacting protein 4 (RAB11FIP4)	OTIGHER7	RFIP4_HUMAN	Affects Expression	[8]
C2 domain-containing protein 5 (C2CD5)	OTI495RD	C2CD5_HUMAN	Affects Expression	[8]
Junctional adhesion molecule-like (JAML)	OTOJHNEV	JAML_HUMAN	Affects Expression	[8]
Coiled-coil domain-containing protein 125 (CCDC125)	OTEK4FFM	CC125_HUMAN	Affects Expression	[8]
5'-3' exonuclease PLD3 (PLD3)	OTL07SP2	PLD3_HUMAN	Affects Expression	[8]
Cyclin-J-like protein (CCNJL)	OTU0SRTC	CCNJL_HUMAN	Affects Expression	[8]
Nostrin (NOSTRIN)	OT0LDSGS	NOSTN_HUMAN	Affects Expression	[8]
Glycerate kinase (GLYCTK)	OTVTBNSM	GLCTK_HUMAN	Affects Expression	[8]
Adhesion G protein-coupled receptor A3 (ADGRA3)	OTPJEV0S	AGRA3_HUMAN	Affects Expression	[8]
Extracellular serine/threonine protein kinase FAM20C (FAM20C)	OTW5YZ7X	FA20C_HUMAN	Affects Expression	[8]
C-Maf-inducing protein (CMIP)	OTZN8Z4A	CMIP_HUMAN	Affects Expression	[8]
mRNA-decapping enzyme 1B (DCP1B)	OTX7PHCI	DCP1B_HUMAN	Affects Expression	[8]
L-fucose kinase (FCSK)	OT4NTHYO	FCSK_HUMAN	Affects Expression	[8]
Regulatory-associated protein of mTOR (RPTOR)	OT4TQZ9F	RPTOR_HUMAN	Affects Expression	[8]
Cell cycle and apoptosis regulator protein 2 (CCAR2)	OTLUDG5T	CCAR2_HUMAN	Affects Expression	[8]
Cyclin-Q (CCNQ)	OT183N7L	CCNQ_HUMAN	Affects Expression	[8]
Histone H2B type 3-B (H2BC26)	OT0E1H99	H2B3B_HUMAN	Affects Expression	[8]
F-box/LRR-repeat protein 16 (FBXL16)	OT3OTNLM	FXL16_HUMAN	Affects Expression	[8]
MPN domain-containing protein (MPND)	OT9XP5AT	MPND_HUMAN	Affects Expression	[8]
Leucine repeat adapter protein 25 (FAM89B)	OT11J9HL	LRA25_HUMAN	Affects Expression	[8]
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (MINDY1)	OTVLF4G5	MINY1_HUMAN	Affects Expression	[8]
Ribonuclease P protein subunit p25-like protein (RPP25L)	OTHZ3E6T	RP25L_HUMAN	Affects Expression	[8]
Protein KRI1 homolog (KRI1)	OT1IGOK7	KRI1_HUMAN	Affects Expression	[8]
SID1 transmembrane family member 2 (SIDT2)	OTU2L002	SIDT2_HUMAN	Affects Expression	[8]
Formylglycine-generating enzyme (SUMF1)	OTALXO2A	SUMF1_HUMAN	Affects Expression	[8]
Prenylcysteine oxidase-like (PCYOX1L)	OTPIYZU7	PCYXL_HUMAN	Affects Expression	[8]
Estradiol 17-beta-dehydrogenase 11 (HSD17B11)	OT3VIM3B	DHB11_HUMAN	Affects Expression	[8]
Aquaporin-11 (AQP11)	OT1IQMHV	AQP11_HUMAN	Affects Expression	[8]
Reticulophagy regulator 2 (RETREG2)	OT5CJTMK	RETR2_HUMAN	Affects Expression	[8]
SERPINE1 mRNA-binding protein 1 (SERBP1)	OTZVSU0X	SERB1_HUMAN	Affects Expression	[8]
Nitric oxide-associated protein 1 (NOA1)	OT9GTOAC	NOA1_HUMAN	Affects Expression	[8]
Polypeptide N-acetylgalactosaminyltransferase 11 (GALNT11)	OTANT9E6	GLT11_HUMAN	Affects Expression	[8]
Protein LSM14 homolog A (LSM14A)	OTFRHO9W	LS14A_HUMAN	Affects Expression	[8]
Protein FAM156A/FAM156B (FAM156A)	OTV17I2D	FA156_HUMAN	Affects Expression	[8]
Folliculin (FLCN)	OTVM78XM	FLCN_HUMAN	Affects Expression	[8]
Retinoic acid-induced protein 3 (GPRC5A)	OTPOCWR7	RAI3_HUMAN	Affects Expression	[8]
Lysine-specific demethylase 2B (KDM2B)	OTDMCVW7	KDM2B_HUMAN	Affects Expression	[8]
Modulator of smoothened protein (MOSMO)	OTTG7G3P	MOSMO_HUMAN	Affects Expression	[8]
SWI/SNF complex subunit SMARCC2 (SMARCC2)	OTC5SNMZ	SMRC2_HUMAN	Affects Expression	[8]
Spermatogenesis-associated protein 20 (SPATA20)	OTWKX0AZ	SPT20_HUMAN	Affects Expression	[8]
DEP domain-containing mTOR-interacting protein (DEPTOR)	OTCBP1BT	DPTOR_HUMAN	Affects Expression	[8]
Bromo adjacent homology domain-containing 1 protein (BAHD1)	OT9YGK94	BAHD1_HUMAN	Affects Expression	[8]
Arrestin domain-containing protein 2 (ARRDC2)	OTVEOXAG	ARRD2_HUMAN	Affects Expression	[8]
N-lysine methyltransferase SETD6 (SETD6)	OTH5APN1	SETD6_HUMAN	Affects Expression	[8]
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1)	OTBR2Q0F	PNPT1_HUMAN	Affects Expression	[8]
Alanine aminotransferase 2 (GPT2)	OTS5VF7N	ALAT2_HUMAN	Affects Expression	[8]
Pleckstrin homology domain-containing family O member 2 (PLEKHO2)	OT2FTK68	PKHO2_HUMAN	Affects Expression	[8]
CDK5 and ABL1 enzyme substrate 1 (CABLES1)	OTMN4XSX	CABL1_HUMAN	Affects Expression	[8]
MORC family CW-type zinc finger protein 4 (MORC4)	OTJBEHNE	MORC4_HUMAN	Affects Expression	[8]
2-phosphoxylose phosphatase 1 (PXYLP1)	OTX8T7F6	PXYP1_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase RNF128 (RNF128)	OTJO86CJ	RN128_HUMAN	Affects Expression	[8]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5)	OTY829Z3	ABHD5_HUMAN	Affects Expression	[8]
Protein FAM222B (FAM222B)	OTV9TL5C	F222B_HUMAN	Affects Expression	[8]
General transcription factor 3C polypeptide 2 (GTF3C2)	OTWDANLJ	TF3C2_HUMAN	Affects Expression	[8]
PHD finger protein 10 (PHF10)	OTWDR4EX	PHF10_HUMAN	Affects Expression	[8]
Coiled-coil domain-containing protein 12 (CCDC12)	OTJM9N54	CCD12_HUMAN	Affects Expression	[8]
Sodium-dependent phosphate transporter 1 (SLC20A1)	OTC3D894	S20A1_HUMAN	Affects Expression	[8]
Pleckstrin homology-like domain family A member 1 (PHLDA1)	OTFTWMIQ	PHLA1_HUMAN	Affects Expression	[8]
RNA polymerase-associated protein LEO1 (LEO1)	OTAPF4PA	LEO1_HUMAN	Affects Expression	[8]
NudC domain-containing protein 2 (NUDCD2)	OTG6BFLI	NUDC2_HUMAN	Affects Expression	[8]
Ataxin-2-like protein (ATXN2L)	OTP5M3R9	ATX2L_HUMAN	Affects Expression	[8]
Gem-associated protein 6 (GEMIN6)	OTE262KF	GEMI6_HUMAN	Affects Expression	[8]
Adhesion G-protein coupled receptor V1 (ADGRV1)	OTLVXHHP	AGRV1_HUMAN	Affects Expression	[8]
Voltage-dependent calcium channel gamma-like subunit (TMEM37)	OT317PEL	CCGL_HUMAN	Affects Expression	[8]
Autism susceptibility gene 2 protein (AUTS2)	OTAEXHSC	AUTS2_HUMAN	Affects Expression	[8]
Peroxynitrite isomerase THAP4 (THAP4)	OTKOAFM1	THAP4_HUMAN	Affects Expression	[8]
Cyclic GMP-AMP phosphodiesterase SMPDL3A (SMPDL3A)	OTQDYH8E	ASM3A_HUMAN	Affects Expression	[8]
ATP-dependent RNA helicase DDX1 (DDX1)	OT3U8FD0	DDX1_HUMAN	Affects Expression	[8]
Sushi domain-containing protein 6 (SUSD6)	OTZS4SKF	SUSD6_HUMAN	Affects Expression	[8]
Nicastrin (NCSTN)	OT5QBTA4	NICA_HUMAN	Affects Expression	[8]
Protein NDRG1 (NDRG1)	OTVO66BO	NDRG1_HUMAN	Affects Expression	[8]
Sortilin-related receptor (SORL1)	OTQ8FFNS	SORL_HUMAN	Affects Expression	[8]
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B)	OT3SQMLU	AN32B_HUMAN	Affects Expression	[8]
TATA-binding protein-associated factor 2N (TAF15)	OTNE038N	RBP56_HUMAN	Affects Expression	[8]
Coronin-2A (CORO2A)	OTVK7PK3	COR2A_HUMAN	Affects Expression	[8]
Protein Jumonji (JARID2)	OT14UM8H	JARD2_HUMAN	Affects Expression	[8]
Neogenin (NEO1)	OTGJ1997	NEO1_HUMAN	Affects Expression	[8]
Amyloid beta precursor protein binding family B member 2 (APBB2)	OT1VD51B	APBB2_HUMAN	Affects Expression	[8]
Golgi apparatus protein 1 (GLG1)	OT7X0W3N	GSLG1_HUMAN	Affects Expression	[8]
Transcription factor GATA-6 (GATA6)	OTO2BC0F	GATA6_HUMAN	Affects Expression	[8]
Ribosomal RNA small subunit methyltransferase NEP1 (EMG1)	OTFDX7HY	NEP1_HUMAN	Affects Expression	[8]
Histone H2B type 1-H (H2BC9)	OTQ9XX72	H2B1H_HUMAN	Affects Expression	[8]
Glycine N-acyltransferase-like protein 1 (GLYATL1)	OTS8JSRY	GLYL1_HUMAN	Affects Expression	[8]
Sorting nexin-21 (SNX21)	OT8O6909	SNX21_HUMAN	Affects Expression	[8]
Protein TMEPAI (PMEPA1)	OTY8Z9UF	PMEPA_HUMAN	Affects Expression	[8]
tRNA modification GTPase GTPBP3, mitochondrial (GTPBP3)	OTU52TXX	GTPB3_HUMAN	Affects Expression	[8]
SOSS complex subunit B2 (NABP1)	OTFTNFHW	SOSB2_HUMAN	Affects Expression	[8]
Transmembrane protein 125 (TMEM125)	OTWF8MC1	TM125_HUMAN	Affects Expression	[8]
Interferon-stimulated gene 20 kDa protein (ISG20)	OTCWRJJW	ISG20_HUMAN	Affects Expression	[8]
Transmembrane protein 45B (TMEM45B)	OTVQCO8N	TM45B_HUMAN	Affects Expression	[8]
Exosome complex component RRP43 (EXOSC8)	OT75ACNG	EXOS8_HUMAN	Affects Expression	[8]
Claudin-23 (CLDN23)	OTN5RV40	CLD23_HUMAN	Affects Expression	[8]
Transmembrane protein 18 (TMEM18)	OT05YQ1E	TMM18_HUMAN	Affects Expression	[8]
Nucleus accumbens-associated protein 2 (NACC2)	OTG9DUIV	NACC2_HUMAN	Affects Expression	[8]
Solute carrier family 25 member 36 (SLC25A36)	OT1T1FMB	S2536_HUMAN	Affects Expression	[8]
Protein FAM241B (FAM241B)	OTLISLRC	F241B_HUMAN	Affects Expression	[8]
Hepatitis A virus cellular receptor 1 (HAVCR1)	OT184CRZ	HAVR1_HUMAN	Affects Expression	[8]
Carboxymethylenebutenolidase homolog (CMBL)	OT8H3S3G	CMBL_HUMAN	Affects Expression	[8]
RecQ-mediated genome instability protein 2 (RMI2)	OTA0HP4S	RMI2_HUMAN	Affects Expression	[8]
Nucleoporin SEH1 (SEH1L)	OTHW13AE	SEH1_HUMAN	Affects Expression	[8]
Required for excision 1-B domain-containing protein (REX1BD)	OTQE6M0H	REX1B_HUMAN	Affects Expression	[8]
C1GALT1-specific chaperone 1 (C1GALT1C1)	OTRTZUF5	C1GLC_HUMAN	Affects Expression	[8]
Small ribosomal subunit protein mS39 (PTCD3)	OTHTOLE0	PTCD3_HUMAN	Affects Expression	[8]
Enhancer of mRNA-decapping protein 3 (EDC3)	OTYS7O69	EDC3_HUMAN	Affects Expression	[8]
Sororin (CDCA5)	OTZLCQ5U	CDCA5_HUMAN	Affects Expression	[8]
Secernin-2 (SCRN2)	OTSG9EUS	SCRN2_HUMAN	Affects Expression	[8]
Diphthamide biosynthesis protein 3 (DPH3)	OT59Q6C4	DPH3_HUMAN	Affects Expression	[8]
tRNA (TRMT61A)	OTMIXQQ6	TRM61_HUMAN	Affects Expression	[8]
Protein LTV1 homolog (LTV1)	OTZILJDI	LTV1_HUMAN	Affects Expression	[8]
Centrosomal protein of 95 kDa (CEP95)	OTYHQVM7	CEP95_HUMAN	Affects Expression	[8]
RUS family member 1 (RUSF1)	OTRIIY6J	RUSF1_HUMAN	Affects Expression	[8]
Unconventional myosin-XIX (MYO19)	OTWEENPY	MYO19_HUMAN	Affects Expression	[8]
Zinc transporter ZIP13 (SLC39A13)	OTF36U59	S39AD_HUMAN	Affects Expression	[8]
SH3 domain-containing YSC84-like protein 1 (SH3YL1)	OTVXOONW	SH3Y1_HUMAN	Affects Expression	[8]
Receptor expression-enhancing protein 6 (REEP6)	OTY4FPO8	REEP6_HUMAN	Affects Expression	[8]
Splicing factor 45 (RBM17)	OT9ROJCL	SPF45_HUMAN	Affects Expression	[8]
Protein phosphatase 1 regulatory subunit 16A (PPP1R16A)	OTOA7YX7	PP16A_HUMAN	Affects Expression	[8]
Kazal-type serine protease inhibitor domain-containing protein 1 (KAZALD1)	OTSFOX2H	KAZD1_HUMAN	Affects Expression	[8]
Putative protein-lysine deacylase ABHD14B (ABHD14B)	OTFIYC6Y	ABHEB_HUMAN	Affects Expression	[8]
Fatty acid hydroxylase domain-containing protein 2 (FAXDC2)	OTRRS828	FXDC2_HUMAN	Affects Expression	[8]
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1)	OTY5HZN5	LRIG1_HUMAN	Affects Expression	[8]
RBPJ-interacting and tubulin-associated protein 1 (RITA1)	OTUH8IPS	RITA1_HUMAN	Affects Expression	[8]
Beta-1,3-galactosyltransferase 6 (B3GALT6)	OTF4HBAT	B3GT6_HUMAN	Affects Expression	[8]
CKLF-like MARVEL transmembrane domain-containing protein 3 (CMTM3)	OTS75IGC	CKLF3_HUMAN	Affects Expression	[8]
AP-4 complex accessory subunit Tepsin (TEPSIN)	OTJIVR84	AP4AT_HUMAN	Affects Expression	[8]
Bcl-2-binding component 3, isoforms 3/4 (BBC3)	OTUAXDAY	BBC3B_HUMAN	Affects Expression	[8]
Pseudouridylate synthase 7 homolog (PUS7)	OTE5AQHJ	PUS7_HUMAN	Affects Expression	[8]
Serine protease FAM111A (FAM111A)	OTVLARLG	F111A_HUMAN	Affects Expression	[8]
Transmembrane protein 237 (TMEM237)	OTQEVL7L	TM237_HUMAN	Affects Expression	[8]
DEP domain-containing protein 7 (DEPDC7)	OT62C942	DEPD7_HUMAN	Affects Expression	[8]
Sperm-associated antigen 5 (SPAG5)	OTCLJ56M	SPAG5_HUMAN	Affects Expression	[8]
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (MCCC1)	OTLOHEQE	MCCA_HUMAN	Affects Expression	[8]
Erbin (ERBIN)	OTNWTUA8	ERBIN_HUMAN	Affects Expression	[8]
Myeloid-associated differentiation marker (MYADM)	OTZTZI7P	MYADM_HUMAN	Affects Expression	[8]
Max-binding protein MNT (MNT)	OTPC4ANL	MNT_HUMAN	Affects Expression	[8]
Selenide, water dikinase 2 (SEPHS2)	OTTFXROR	SPS2_HUMAN	Affects Expression	[8]
Krueppel-like factor 6 (KLF6)	OTQY9S7F	KLF6_HUMAN	Increases Expression	[37]
Eukaryotic translation initiation factor 3 subunit C (EIF3C)	OTR8RF9X	EIF3C_HUMAN	Affects Expression	[8]
SPRY domain-containing SOCS box protein 2 (SPSB2)	OT7ZVT8R	SPSB2_HUMAN	Affects Expression	[8]
Kinesin-like protein KIF2C (KIF2C)	OTJ8G3NP	KIF2C_HUMAN	Affects Expression	[8]
Pituitary homeobox 2 (PITX2)	OTWMXAOY	PITX2_HUMAN	Affects Expression	[8]
Aconitate hydratase, mitochondrial (ACO2)	OTF2UVNV	ACON_HUMAN	Affects Expression	[8]
Endothelial PAS domain-containing protein 1 (EPAS1)	OTRE3O8U	EPAS1_HUMAN	Affects Expression	[8]
Protein smoothened (SMO)	OTXXE208	SMO_HUMAN	Affects Expression	[8]
Probable rRNA-processing protein EBP2 (EBNA1BP2)	OTBRVMZH	EBP2_HUMAN	Affects Expression	[8]
AT-rich interactive domain-containing protein 3A (ARID3A)	OTZZ4SFP	ARI3A_HUMAN	Affects Expression	[8]
Histone H2B type 1-N (H2BC15)	OTU39CFZ	H2B1N_HUMAN	Affects Expression	[8]
Histone H2B type 1-L (H2BC13)	OTIS8L6R	H2B1L_HUMAN	Affects Expression	[8]
Cbp/p300-interacting transactivator 2 (CITED2)	OT812TV7	CITE2_HUMAN	Affects Expression	[8]
A-kinase anchor protein 9 (AKAP9)	OT7Z2YRP	AKAP9_HUMAN	Affects Expression	[8]
Galactosylceramide sulfotransferase (GAL3ST1)	OTSFFZRD	G3ST1_HUMAN	Affects Expression	[8]
Condensin complex subunit 3 (NCAPG)	OT1AI9EO	CND3_HUMAN	Affects Expression	[8]
Glutamate-rich WD repeat-containing protein 1 (GRWD1)	OT6M13ZV	GRWD1_HUMAN	Affects Expression	[8]
Adenine nucleotide translocase lysine N-methyltransferase (ANTKMT)	OTDV54V6	ANKMT_HUMAN	Affects Expression	[8]
Selenoprotein S (SELENOS)	OTUEWIU9	SELS_HUMAN	Affects Expression	[8]
Fermitin family homolog 1 (FERMT1)	OT626PBA	FERM1_HUMAN	Affects Expression	[8]
Hephaestin (HEPH)	OTZ2F15Z	HEPH_HUMAN	Affects Expression	[8]
BUD13 homolog (BUD13)	OTXG6MX5	BUD13_HUMAN	Affects Expression	[8]
Serine/arginine-rich splicing factor 8 (SRSF8)	OTHFCYTK	SRSF8_HUMAN	Affects Expression	[8]
TM2 domain-containing protein 3 (TM2D3)	OT6MS96W	TM2D3_HUMAN	Affects Expression	[8]
Uridine diphosphate glucose pyrophosphatase NUDT22 (NUDT22)	OTV09JH1	NUD22_HUMAN	Affects Expression	[8]
La-related protein 6 (LARP6)	OTUQ9QS9	LARP6_HUMAN	Affects Expression	[8]
Transmembrane protein 79 (TMEM79)	OTEC6EFU	TMM79_HUMAN	Affects Expression	[8]
Protein PIMREG (PIMREG)	OTKC8T3E	PIMRE_HUMAN	Affects Expression	[8]
Deubiquitinase DESI2 (DESI2)	OTHUOKOC	DESI2_HUMAN	Affects Expression	[8]
Mini-chromosome maintenance complex-binding protein (MCMBP)	OTQ6WO7A	MCMBP_HUMAN	Affects Expression	[8]
Histone H2A.J (H2AJ)	OTVA4XTW	H2AJ_HUMAN	Affects Expression	[8]
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 (LRFN3)	OT35U2SQ	LRFN3_HUMAN	Affects Expression	[8]
Nucleoporin NDC1 (NDC1)	OTF2GQC1	NDC1_HUMAN	Affects Expression	[8]
Probable ATP-dependent RNA helicase DDX23 (DDX23)	OTBJHS8C	DDX23_HUMAN	Affects Expression	[8]
Dehydrogenase/reductase SDR family member 6 (BDH2)	OTDD7G8S	DHRS6_HUMAN	Affects Expression	[8]
Arginine/serine-rich protein 1 (RSRP1)	OTOAZLCL	RSRP1_HUMAN	Affects Expression	[8]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2)	OTZ092ZJ	THIC_HUMAN	Affects Expression	[8]
Sodium channel modifier 1 (SCNM1)	OT505E7T	SCNM1_HUMAN	Affects Expression	[8]
Cell division cycle-associated protein 7 (CDCA7)	OT12HDZY	CDCA7_HUMAN	Affects Expression	[8]
Group XIIB secretory phospholipase A2-like protein (PLA2G12B)	OTY7GXA6	PG12B_HUMAN	Affects Expression	[8]
Hydroxycarboxylic acid receptor 1 (HCAR1)	OT5ZSESQ	HCAR1_HUMAN	Affects Expression	[8]
Bardet-Biedl syndrome 2 protein (BBS2)	OTPF9JIB	BBS2_HUMAN	Affects Expression	[8]
Solute carrier family 12 member 9 (SLC12A9)	OTR7VRAK	S12A9_HUMAN	Affects Expression	[8]
Protein DGCR6L (DGCR6L)	OTE0Z7WM	DGC6L_HUMAN	Affects Expression	[8]
Alpha-(1,6)-fucosyltransferase (FUT8)	OTJJCVG1	FUT8_HUMAN	Affects Expression	[8]
Transmembrane protease serine 13 (TMPRSS13)	OTMAOAP3	TMPSD_HUMAN	Affects Expression	[8]
GTP-binding protein 4 (GTPBP4)	OT6ZHAWC	GTPB4_HUMAN	Affects Expression	[8]
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (DPH1)	OT0QU3JY	DPH1_HUMAN	Affects Expression	[8]
Thiamine transporter 2 (SLC19A3)	OTOWP1CT	S19A3_HUMAN	Affects Expression	[8]
Tripartite motif-containing protein 2 (TRIM2)	OT0V1YVC	TRIM2_HUMAN	Affects Expression	[8]
Keratin, type I cytoskeletal 23 (KRT23)	OTQW6UAG	K1C23_HUMAN	Affects Expression	[8]
Brain-specific serine protease 4 (PRSS22)	OTANEFGM	BSSP4_HUMAN	Affects Expression	[8]
Coiled-coil domain-containing protein 90B, mitochondrial (CCDC90B)	OTFFWB0C	CC90B_HUMAN	Affects Expression	[8]
NIF3-like protein 1 (NIF3L1)	OT4MP90J	NIF3L_HUMAN	Affects Expression	[8]
Mitochondrial fission factor (MFF)	OTEVIXOM	MFF_HUMAN	Affects Expression	[8]
Mitochondrial disaggregase (CLPB)	OT1I0IBK	CLPB_HUMAN	Affects Expression	[8]
Protein FAM107B (FAM107B)	OT5RG4J0	F107B_HUMAN	Affects Expression	[8]
Bromodomain-containing protein 8 (BRD8)	OTIKS3PC	BRD8_HUMAN	Affects Expression	[8]
Probable ATP-dependent RNA helicase DDX47 (DDX47)	OTS7KMYV	DDX47_HUMAN	Affects Expression	[8]
Anaphase-promoting complex subunit 1 (ANAPC1)	OT2YY35L	APC1_HUMAN	Affects Expression	[8]
Epsin-3 (EPN3)	OTNNYDT6	EPN3_HUMAN	Affects Expression	[8]
DNA replication factor Cdt1 (CDT1)	OTVY53VG	CDT1_HUMAN	Affects Expression	[8]
SH3 domain-binding glutamic acid-rich-like protein 3 (SH3BGRL3)	OTKMW34I	SH3L3_HUMAN	Affects Expression	[8]
Semaphorin-6A (SEMA6A)	OTDQ7QAW	SEM6A_HUMAN	Affects Expression	[8]
Testis-specific Y-encoded-like protein 2 (TSPYL2)	OTGGW2EF	TSYL2_HUMAN	Affects Expression	[8]
Pinin (PNN)	OT0HXICH	PININ_HUMAN	Affects Expression	[8]
Ammonium transporter Rh type B (RHBG)	OT82KXU3	RHBG_HUMAN	Affects Expression	[8]
Transmembrane protein 245 (TMEM245)	OTR7KEXW	TM245_HUMAN	Affects Expression	[8]
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10)	OT5HFZXU	BACD3_HUMAN	Affects Expression	[8]
Major facilitator superfamily domain-containing protein 1 (MFSD1)	OTPRRXCX	MFSD1_HUMAN	Affects Expression	[8]
SPARC-related modular calcium-binding protein 2 (SMOC2)	OTK1EQ49	SMOC2_HUMAN	Affects Expression	[8]
Pancreatic progenitor cell differentiation and proliferation factor (PPDPF)	OT4LO2GJ	PPDPF_HUMAN	Affects Expression	[8]
F-box/LRR-repeat protein 15 (FBXL15)	OTFGBM4Z	FXL15_HUMAN	Affects Expression	[8]
Serine/threonine-protein kinase PLK3 (PLK3)	OT19CT2Z	PLK3_HUMAN	Affects Expression	[8]
RIB43A-like with coiled-coils protein 2 (RIBC2)	OTDB4FM2	RIBC2_HUMAN	Affects Expression	[8]
Regulator of cell cycle RGCC (RGCC)	OTYJMLWM	RGCC_HUMAN	Affects Expression	[8]
HEAT repeat-containing protein 1 (HEATR1)	OTOWIB9Z	HEAT1_HUMAN	Affects Expression	[8]
Probable ATP-dependent RNA helicase DHX35 (DHX35)	OTOP4UCG	DHX35_HUMAN	Affects Expression	[8]
Occludin/ELL domain-containing protein 1 (OCEL1)	OTS4R6CX	OCEL1_HUMAN	Affects Expression	[8]
Reticulophagy regulator 1 (RETREG1)	OTYOSLZX	RETR1_HUMAN	Affects Expression	[8]
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2)	OT6OD55E	ES8L2_HUMAN	Affects Expression	[8]
Epithelial splicing regulatory protein 2 (ESRP2)	OTVTKJ4I	ESRP2_HUMAN	Affects Expression	[8]
Intraflagellar transport protein 22 homolog (IFT22)	OTUY564Y	IFT22_HUMAN	Affects Expression	[8]
Receptor expression-enhancing protein 1 (REEP1)	OTEMVFX7	REEP1_HUMAN	Affects Expression	[8]
Histone-lysine N-methyltransferase EHMT1 (EHMT1)	OT6QC8GK	EHMT1_HUMAN	Affects Expression	[8]
Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2)	OT3Q11WQ	I20L2_HUMAN	Affects Expression	[8]
RING finger protein 122 (RNF122)	OT8RE3IM	RN122_HUMAN	Affects Expression	[8]
Ketosamine-3-kinase (FN3KRP)	OT9HR05S	KT3K_HUMAN	Affects Expression	[8]
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (RSAD1)	OTHNSDGW	RSAD1_HUMAN	Affects Expression	[8]
Phosphopantothenate--cysteine ligase (PPCS)	OT344CQO	PPCS_HUMAN	Affects Expression	[8]
MLX-interacting protein (MLXIP)	OT30UNI7	MLXIP_HUMAN	Affects Expression	[8]
Melanoma-associated antigen F1 (MAGEF1)	OTUU40U3	MAGF1_HUMAN	Affects Expression	[8]
Pleckstrin homology domain-containing family A member 1 (PLEKHA1)	OT66PF24	PKHA1_HUMAN	Affects Expression	[8]
Solute carrier family 38 member 10 (SLC38A10)	OTXPUL6S	S38AA_HUMAN	Affects Expression	[8]
UPF0606 protein KIAA1549 (KIAA1549)	OTA5B18F	K1549_HUMAN	Affects Expression	[8]
Post-GPI attachment to proteins factor 6 (PGAP6)	OTGYID4C	PGAP6_HUMAN	Affects Expression	[8]
Breast cancer metastasis-suppressor 1 (BRMS1)	OTV5A6LL	BRMS1_HUMAN	Affects Expression	[8]
Magnesium transporter MRS2 homolog, mitochondrial (MRS2)	OTICD11V	MRS2_HUMAN	Affects Expression	[8]
Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC)	OTRBGH71	GOPC_HUMAN	Affects Expression	[8]
Unconventional myosin-X (MYO10)	OTHB78ZQ	MYO10_HUMAN	Affects Expression	[8]
SIN3-HDAC complex-associated factor (SINHCAF)	OTHMZZ0A	SHCAF_HUMAN	Affects Expression	[8]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A)	OT5V52LN	TNR12_HUMAN	Affects Expression	[8]
Inward rectifier potassium channel 16 (KCNJ16)	OT174UPV	KCJ16_HUMAN	Affects Expression	[8]
A-kinase-interacting protein 1 (AKIP1)	OT7XPG27	AKIP1_HUMAN	Affects Expression	[8]
G-protein coupled receptor family C group 5 member C (GPRC5C)	OT45AJT3	GPC5C_HUMAN	Affects Expression	[8]
Kinesin-like protein KIF13B (KIF13B)	OTAFS1YV	KI13B_HUMAN	Affects Expression	[8]
SLC2A4 regulator (SLC2A4RG)	OTW3LX8D	S2A4R_HUMAN	Affects Expression	[8]
Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1)	OTZWDB2X	4ET_HUMAN	Affects Expression	[8]
N-lysine methyltransferase SMYD2 (SMYD2)	OTN8035R	SMYD2_HUMAN	Affects Expression	[8]
Serine/threonine-protein kinase LATS2 (LATS2)	OT6XO8JP	LATS2_HUMAN	Affects Expression	[8]
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3)	OTAUR5TG	PLCC_HUMAN	Affects Expression	[8]
Ras association domain-containing protein 1 (RASSF1)	OTEZIPB7	RASF1_HUMAN	Affects Expression	[8]
Mitochondrial import receptor subunit TOM22 homolog (TOMM22)	OTTFA8FH	TOM22_HUMAN	Affects Expression	[8]
Carbohydrate sulfotransferase 7 (CHST7)	OT9HCUST	CHST7_HUMAN	Affects Expression	[8]
Phenylalanine--tRNA ligase beta subunit (FARSB)	OT8N9TT5	SYFB_HUMAN	Affects Expression	[8]
Ribosome biogenesis protein SLX9 homolog (SLX9)	OTNVADE7	SLX9_HUMAN	Affects Expression	[8]
Semaphorin-4G (SEMA4G)	OT7BCPU7	SEM4G_HUMAN	Affects Expression	[8]
Protein FAM217B (FAM217B)	OTDB4M8G	F217B_HUMAN	Affects Expression	[8]
Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1)	OT6C1WQD	ACS2L_HUMAN	Affects Expression	[8]
p53 and DNA damage-regulated protein 1 (PDRG1)	OT8ZMFZE	PDRG1_HUMAN	Affects Expression	[8]
Integrator complex subunit 10 (INTS10)	OTO356QQ	INT10_HUMAN	Affects Expression	[8]
DNA-directed RNA polymerase III subunit RPC5 (POLR3E)	OT69PWBM	RPC5_HUMAN	Affects Expression	[8]
Mediator of RNA polymerase II transcription subunit 9 (MED9)	OT59OKEJ	MED9_HUMAN	Affects Expression	[8]
Host cell factor C1 regulator 1 (HCFC1R1)	OTGDPS5C	HPIP_HUMAN	Affects Expression	[8]
Oxidative stress-responsive serine-rich protein 1 (OSER1)	OTN8C6JQ	OSER1_HUMAN	Affects Expression	[8]
Cell growth-regulating nucleolar protein (LYAR)	OTQNA67C	LYAR_HUMAN	Affects Expression	[8]
Nuclear distribution protein nudE homolog 1 (NDE1)	OT2N8Q17	NDE1_HUMAN	Affects Expression	[8]
Non-structural maintenance of chromosomes element 4 homolog A (NSMCE4A)	OTAXU2QD	NSE4A_HUMAN	Affects Expression	[8]
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (COA4)	OT8319UQ	COA4_HUMAN	Affects Expression	[8]
BET1-like protein (BET1L)	OT5QVYBZ	BET1L_HUMAN	Affects Expression	[8]
G-protein coupled receptor family C group 5 member B (GPRC5B)	OTF3S5E3	GPC5B_HUMAN	Affects Expression	[8]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1)	OTY6ZHVA	RGL1_HUMAN	Affects Expression	[8]
Leucine-rich repeat transmembrane protein FLRT3 (FLRT3)	OT3XMZU3	FLRT3_HUMAN	Affects Expression	[8]
LIM and cysteine-rich domains protein 1 (LMCD1)	OT3AWE8O	LMCD1_HUMAN	Affects Expression	[8]
Actin-related protein 3B (ACTR3B)	OTNEC9UT	ARP3B_HUMAN	Affects Expression	[8]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1)	OTJISZOX	PLCE1_HUMAN	Affects Expression	[8]
Teneurin-3 (TENM3)	OTWY13GR	TEN3_HUMAN	Affects Expression	[8]
Ribosome-binding protein 1 (RRBP1)	OT4ZTPTM	RRBP1_HUMAN	Affects Expression	[8]
FERM domain-containing protein 4A (FRMD4A)	OTJDTIK2	FRM4A_HUMAN	Affects Expression	[8]
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)	OTSB4XO0	DPM3_HUMAN	Affects Expression	[8]
DNA (DNMT3B)	OTZ0JCNP	DNM3B_HUMAN	Affects Expression	[8]
Headcase protein homolog (HECA)	OTWG3P6C	HDC_HUMAN	Affects Expression	[8]
Tight junction protein ZO-2 (TJP2)	OTQUY6BV	ZO2_HUMAN	Affects Expression	[8]
Gamma-adducin (ADD3)	OTDRSHAZ	ADDG_HUMAN	Affects Expression	[8]
Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1)	OTHRVJQC	LRWD1_HUMAN	Affects Expression	[8]
Translocation protein SEC63 homolog (SEC63)	OT1ICPMK	SEC63_HUMAN	Affects Expression	[8]
Contactin-associated protein-like 2 (CNTNAP2)	OT48T2ZP	CNTP2_HUMAN	Affects Expression	[8]
NADH-cytochrome b5 reductase 1 (CYB5R1)	OTMDHMLA	NB5R1_HUMAN	Affects Expression	[8]
Poly(U)-binding-splicing factor PUF60 (PUF60)	OTG90DYF	PUF60_HUMAN	Affects Expression	[8]
ATPase inhibitor, mitochondrial (ATP5IF1)	OTQFD73H	ATIF1_HUMAN	Affects Expression	[8]
Probable G-protein coupled receptor 160 (GPR160)	OTMXJT73	GP160_HUMAN	Affects Expression	[8]
Protein argonaute-1 (AGO1)	OTD3R434	AGO1_HUMAN	Affects Expression	[8]
2-oxoglutarate dehydrogenase-like, mitochondrial (OGDHL)	OT1AZK6R	OGDHL_HUMAN	Affects Expression	[8]
Neurabin-1 (PPP1R9A)	OTJL2TOC	NEB1_HUMAN	Affects Expression	[8]
Glutamate receptor ionotropic, delta-1 (GRID1)	OTJ3WIKC	GRID1_HUMAN	Affects Expression	[8]
Frizzled-4 (FZD4)	OTGLZIE0	FZD4_HUMAN	Affects Expression	[8]
Targeting protein for Xklp2 (TPX2)	OTWLJYH0	TPX2_HUMAN	Affects Expression	[8]
Transcription factor MafF (MAFF)	OT9B7MX0	MAFF_HUMAN	Affects Expression	[8]
U3 small nucleolar RNA-associated protein NOL7 (NOL7)	OTIJ1KQI	UTP16_HUMAN	Affects Expression	[8]
Protein timeless homolog (TIMELESS)	OTD8DCBJ	TIM_HUMAN	Affects Expression	[8]
ATP-sensitive inward rectifier potassium channel 14 (KCNJ14)	OTBTT4MC	KCJ14_HUMAN	Affects Expression	[8]
Zinc finger protein PLAGL2 (PLAGL2)	OT6AP4V2	PLAL2_HUMAN	Affects Expression	[8]
LIM/homeobox protein Lhx6 (LHX6)	OT47UQZ5	LHX6_HUMAN	Affects Expression	[8]
Forkhead box protein J3 (FOXJ3)	OTXAUJ47	FOXJ3_HUMAN	Affects Expression	[8]
SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)	OTSQTPFQ	SHAN2_HUMAN	Affects Expression	[8]
Serine/arginine repetitive matrix protein 2 (SRRM2)	OTSIMMC9	SRRM2_HUMAN	Affects Expression	[8]
Dexamethasone-induced Ras-related protein 1 (RASD1)	OT2BAJHK	RASD1_HUMAN	Affects Expression	[8]
Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)	OTB17Q43	SIA10_HUMAN	Affects Expression	[8]
Myelin regulatory factor (MYRF)	OTKF6AEB	MYRF_HUMAN	Affects Expression	[8]
Pleckstrin homology domain-containing family A member 6 (PLEKHA6)	OTALCXKW	PKHA6_HUMAN	Affects Expression	[8]
Fibronectin type-III domain-containing protein 3A (FNDC3A)	OTUX3S2I	FND3A_HUMAN	Affects Expression	[8]
Angiomotin-like protein 2 (AMOTL2)	OTRCTKV9	AMOL2_HUMAN	Affects Expression	[8]
R3H domain-containing protein 2 (R3HDM2)	OTMJ3S6J	R3HD2_HUMAN	Affects Expression	[8]
Hypoxia-inducible factor 3-alpha (HIF3A)	OTPWAAMC	HIF3A_HUMAN	Affects Expression	[8]
Ragulator complex protein LAMTOR2 (LAMTOR2)	OTHEDISB	LTOR2_HUMAN	Affects Expression	[8]
Lambda-crystallin homolog (CRYL1)	OT0SJSJM	CRYL1_HUMAN	Affects Expression	[8]
Nucleolar protein 58 (NOP58)	OTP536HD	NOP58_HUMAN	Affects Expression	[8]
Oligoribonuclease, mitochondrial (REXO2)	OTLKKURG	ORN_HUMAN	Affects Expression	[8]
Nucleolar protein 16 (NOP16)	OT2829ZC	NOP16_HUMAN	Affects Expression	[8]
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1)	OTS5S837	PPIL1_HUMAN	Affects Expression	[8]
Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2)	OTURGRA8	MSRB2_HUMAN	Affects Expression	[8]
Serine-threonine kinase receptor-associated protein (STRAP)	OTT3T7QT	STRAP_HUMAN	Affects Expression	[8]
Rhomboid domain-containing protein 3 (RHBDD3)	OTJ3OLC8	RHBD3_HUMAN	Affects Expression	[8]
Transformation/transcription domain-associated protein (TRRAP)	OT68OI2Y	TRRAP_HUMAN	Affects Expression	[8]
Nuclear factor erythroid 2-related factor 3 (NFE2L3)	OT1MGXT0	NF2L3_HUMAN	Affects Expression	[8]
FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1)	OTL1EBTM	FARP1_HUMAN	Affects Expression	[8]
Ribosomal biogenesis protein LAS1L (LAS1L)	OTG4I2A1	LAS1L_HUMAN	Affects Expression	[8]
E3 ubiquitin-protein ligase RNF114 (RNF114)	OTF06FRP	RN114_HUMAN	Affects Expression	[8]
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22)	OTJMHX1V	TIM22_HUMAN	Affects Expression	[8]
Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9)	OTK7PDNN	TIM9_HUMAN	Affects Expression	[8]
Insulin-induced gene 2 protein (INSIG2)	OTX4VY51	INSI2_HUMAN	Affects Expression	[8]
Melanoma-associated antigen D1 (MAGED1)	OT6EOLFC	MAGD1_HUMAN	Affects Expression	[8]
Sorting nexin-14 (SNX14)	OTXI9C1E	SNX14_HUMAN	Affects Expression	[8]
Sorting nexin-9 (SNX9)	OTLNQ0ZM	SNX9_HUMAN	Affects Expression	[8]
Heme transporter FLVCR1 (FLVCR1)	OT9XCFOC	FLVC1_HUMAN	Affects Expression	[8]
Nuclear receptor corepressor 2 (NCOR2)	OTY917X0	NCOR2_HUMAN	Affects Expression	[8]
Cysteine desulfurase (NFS1)	OT0HUS40	NFS1_HUMAN	Affects Expression	[8]
Cilia- and flagella-associated protein 20 (CFAP20)	OTIG8TR5	CFA20_HUMAN	Affects Expression	[8]
Peroxisomal membrane protein 4 (PXMP4)	OTNDYSHU	PXMP4_HUMAN	Affects Expression	[8]
Aldehyde dehydrogenase family 3 member B1 (ALDH3B1)	OT5NEUQE	AL3B1_HUMAN	Decreases Response To Substance	[38]
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2)	OTGEDDM2	ARK72_HUMAN	Decreases Response To Substance	[39]
Bis(5'-adenosyl)-triphosphatase (FHIT)	OTGWBSLA	FHIT_HUMAN	Increases Response To Substance	[40]
Superoxide dismutase , mitochondrial (SOD2)	OTIWXGZ9	SODM_HUMAN	Decreases Response To Substance	[41]
Collagen alpha-1(IV) chain (COL4A1)	OTL6D1YE	CO4A1_HUMAN	Increases ADR	[9]
Dehydrogenase/reductase SDR family member 11 (DHRS11)	OTU3J0ZL	DHR11_HUMAN	Increases Reduction	[42]
L-xylulose reductase (DCXR)	OTYVXRXB	DCXR_HUMAN	Increases Metabolism	[43]

Indication(s) of OZ277

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Approved	[4]

OZ277 Interacts with 1 DTT Molecule(s)

DTT Name	DTT ID	UniProt ID	Mode of Action	REF
Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A)	TTZVSJ2	NOUNIPROTAC	Inhibitor	[4]

References

• [1] CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125966
• [2] FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 002139.
• [3] ClinicalTrials.gov (NCT01272830) Double-Blinded Clinical Trial Using ApatoneB for Symptomatic Postoperative Total Joint Replacements. U.S. National Institutes of Health.
• [4] The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Curr Med Chem. 2008;15(2):161-71.
• [5] Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells. Chem Biol Interact. 2019 Aug 25;309:108725. doi: 10.1016/j.cbi.2019.108725. Epub 2019 Jun 22.
• [6] Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. Cancer Res. 2002 Nov 1;62(21):6246-54.
• [7] Time series analysis of oxidative stress response patterns in HepG2: a toxicogenomics approach. Toxicology. 2013 Apr 5;306:24-34.
• [8] Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol Sci. 2010 Apr;114(2):193-203. doi: 10.1093/toxsci/kfp309. Epub 2009 Dec 31.
• [9] ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
• [10] Evidence in hyponatremia related to inappropriate secretion of ADH that V1 receptor stimulation contributes to the increase in renal uric acid clearance. J Am Soc Nephrol. 1996 May;7(5):805-10.
• [11] Inhibition by SKF-525A of the aldehyde oxidase-mediated metabolism of the experimental antitumour agent acridine carboxamide. Biochem Pharmacol. 1993 May 25;45(10):2159-62.
• [12] The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3279-86.
• [13] Rat hepatic CYP1A1 and CYP1A2 induction by menadione. Toxicol Lett. 2005 Feb 15;155(2):253-8.
• [14] CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling. Hepatology. 2004 Feb;39(2):444-55.
• [15] Polycyclic aromatic hydrocarbon quinones and glutathione thioethers as substrates and inhibitors of the human placental NADP-linked 15-hydroxyprostaglandin dehydrogenase. J Biol Chem. 1987 Sep 15;262(26):12448-51.
• [16] Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1. Mol Cell Biochem. 2008 Aug;315(1-2):113-21.
• [17] Purification and properties of 5,10-methylenetetrahydrofolate reductase, an iron-sulfur flavoprotein from Clostridium formicoaceticum. J Biol Chem. 1984 Sep 10;259(17):10845-9.
• [18] Differences in the efficiency of reductive activation of methionine synthase and exogenous electron acceptors between the common polymorphic variants of human methionine synthase reductase. Biochemistry. 2002 Nov 12;41(45):13378-85.
• [19] Role of glutathione reductase during menadione-induced NADPH oxidation in isolated rat hepatocytes. Biochem Pharmacol. 1987 Nov 15;36(22):3879-84.
• [20] Sepiapterin reductase mediates chemical redox cycling in lung epithelial cells. J Biol Chem. 2013 Jun 28;288(26):19221-37.
• [21] Purification and characterization of wild-type and mutant "classical" nitroreductases of Salmonella typhimurium. L33R mutation greatly diminishes binding of FMN to the nitroreductase of S. typhimurium. J Biol Chem. 1998 Sep 11;273(37):23922-8.
• [22] Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms. Am J Physiol Cell Physiol. 2009 Dec;297(6):C1358-67. doi: 10.1152/ajpcell.00216.2009. Epub 2009 Aug 12.
• [23] Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP. Chem Res Toxicol. 2011 Jun 20;24(6):950-9. doi: 10.1021/tx200123z. Epub 2011 May 25.
• [24] Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. Food Chem Toxicol. 2021 Dec;158:112664. doi: 10.1016/j.fct.2021.112664. Epub 2021 Nov 9.
• [25] Effect of cell differentiation for neuroblastoma by vitamin k analogs. Jpn J Clin Oncol. 2009 Apr;39(4):251-9. doi: 10.1093/jjco/hyp011. Epub 2009 Mar 8.
• [26] Molecular mechanisms of the antiproliferative effect of vitamin K3 on Jurkat cells. Biochemistry (Mosc). 1999 Apr;64(4):468-72.
• [27] Vitamin K3 (menadione)-induced oncosis associated with keratin 8 phosphorylation and histone H3 arylation. Mol Pharmacol. 2005 Sep;68(3):606-15. doi: 10.1124/mol.105.013474. Epub 2005 Jun 6.
• [28] Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules. Int J Oncol. 2005 Aug;27(2):505-11.
• [29] Altered redox state of luminal pyridine nucleotides facilitates the sensitivity towards oxidative injury and leads to endoplasmic reticulum stress dependent autophagy in HepG2 cells. Int J Biochem Cell Biol. 2010 Jan;42(1):157-66. doi: 10.1016/j.biocel.2009.10.004. Epub 2009 Oct 9.
• [30] DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione. Biochem Biophys Res Commun. 2006 Nov 10;350(1):50-5. doi: 10.1016/j.bbrc.2006.08.174. Epub 2006 Sep 18.
• [31] Menadione biphasically controls JNK-linked cell death in leukemia Jurkat T cells. Antioxid Redox Signal. 2002 Jun;4(3):371-8. doi: 10.1089/15230860260196173.
• [32] Modulation of notch signaling pathway to prevent H2O2/menadione-induced SK-N-MC cells death by EUK134. Cell Mol Neurobiol. 2014 Oct;34(7):1037-45. doi: 10.1007/s10571-014-0079-0. Epub 2014 Jul 9.
• [33] Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs. Nucleic Acids Res. 2014 Jan;42(2):1196-208. doi: 10.1093/nar/gkt903. Epub 2013 Oct 7.
• [34] Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis. J Biol Chem. 1999 Oct 29;274(44):31150-4. doi: 10.1074/jbc.274.44.31150.
• [35] Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein. Free Radic Biol Med. 2003 Sep 1;35(5):528-39. doi: 10.1016/s0891-5849(03)00358-7.
• [36] A Gene Expression Biomarker Predicts Heat Shock Factor 1 Activation in a Gene Expression Compendium. Chem Res Toxicol. 2021 Jul 19;34(7):1721-1737. doi: 10.1021/acs.chemrestox.0c00510. Epub 2021 Jun 25.
• [37] Oxidative stress modulates KLF6Full and its splice variants. Alcohol Clin Exp Res. 2012 Nov;36(11):1851-62. doi: 10.1111/j.1530-0277.2012.01798.x. Epub 2012 Apr 6.
• [38] Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress. Free Radic Biol Med. 2010 Nov 15;49(9):1432-43. doi: 10.1016/j.freeradbiomed.2010.08.004. Epub 2010 Aug 10.
• [39] Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells. Chem Biol Interact. 2012 Jan 5;195(1):25-34. doi: 10.1016/j.cbi.2011.09.007. Epub 2011 Oct 5.
• [40] Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12753-8. doi: 10.1073/pnas.0906484106. Epub 2009 Jul 21.
• [41] Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase. J Biol Chem. 2004 Feb 27;279(9):7512-20. doi: 10.1074/jbc.M307677200. Epub 2003 Dec 3.
• [42] Rabbit dehydrogenase/reductase SDR family member 11 (DHRS11): Its identity with acetohexamide reductase with broad substrate specificity and inhibitor sensitivity, different from human DHRS11. Chem Biol Interact. 2019 May 25;305:12-20. doi: 10.1016/j.cbi.2019.03.026. Epub 2019 Mar 26.
• [43] Diacetyl/l-xylulose reductase mediates chemical redox cycling in lung epithelial cells. Chem Res Toxicol. 2017 Jul 17;30(7):1406-1418.