Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMUNK59)

Drug Name
Bafilomycin A1 Drug Info
Synonyms
bafilomycin A1; 88899-55-2; MFCD06795130; CHEMBL290814; CHEBI:22689; (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one; Bafilomycin; NSC381866; Bafilomycin A1/; Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-; Bafilomycin A1 from Streptomyces griseus; BSPBio_001470; MEGxm0_000385; SCHEMBL13775181; ACon0_000813; HMS3402J12; Bafilomycin A1 Ready Made Solution; ABP000610; BDBM50064186; AKOS030213158; ZINC169647947; DB06733; MCULE-2359469972; NCGC00163426-02; (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one; Q4841341; (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyl-tetrahydropyran-2-yl]-2-hydroxy-1-methyl-butyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
Indication
Disease Entry ICD 11 Status REF
B-cell acute lymphoblastic leukaemia 2B33.3 Investigative [1]
Cross-matching ID
PubChem CID
6436223
ChEBI ID
CHEBI:22689
CAS Number
CAS 88899-55-2
TTD Drug ID
DMUNK59

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Vacuolar-type proton ATPase (v-ATPase)
Drug Name Drug ID Indication ICD 11 Highest Status REF
WY-47766 DM7VCDZ Osteoporosis FB83.0 Discontinued in Phase 2 [11]
SB 242784 DMFXJDL Arterial calcification BD52.Y Preclinical [12]
Salicylihalamide A DMGXVRZ Solid tumour/cancer 2A00-2F9Z Preclinical [13]
FR167356 DMF53Z7 Osteoporosis FB83.0 Preclinical [14]
Lobatamide A DM2GBEW Discovery agent N.A. Investigative [13]
Lobatamide C DMFIDJS Discovery agent N.A. Investigative [13]
Oximidine II DMW6K80 Discovery agent N.A. Investigative [13]
Lobatamide D DMG706J Discovery agent N.A. Investigative [13]
Lobatamide B DMD91RI Discovery agent N.A. Investigative [13]
Oximidine I DMG6O0L Discovery agent N.A. Investigative [13]
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Drug(s) Affected By Apoptotic protease-activating factor 1 (APAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [17]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [19]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [20]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [21]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [22]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [23]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [24]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [29]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [30]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [31]
Gefitinib DM15F0X Colon adenocarcinoma Approved [32]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [33]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [35]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [26]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [36]
Paclitaxel DMLB81S Breast carcinoma Approved [37]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [38]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [28]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [29]
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Drug(s) Affected By Steroidogenic factor 1 (NR5A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ethanol DMDRQZU Chronic pain MG30 Approved [41]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [42]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [43]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [44]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [45]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [46]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [47]
27-hydroxycholesterol DM2L6OZ Discovery agent N.A. Investigative [48]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [49]
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Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [50]
Verapamil DMA7PEW Angina pectoris BA40 Approved [51]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [52]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Selenium DM25CGV N. A. N. A. Approved [54]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [56]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [59]
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Drug(s) Affected By Zinc finger protein SNAI1 (SNAI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [65]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [66]
Leflunomide DMR8ONJ Arthritis FA20 Approved [67]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [68]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [69]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [70]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [39]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [71]
Diazepam DM08E9O Alcohol withdrawal Approved [72]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [73]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [74]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [75]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
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Drug(s) Affected By Cathepsin D (CTSD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [84]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [85]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
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Drug(s) Affected By Procathepsin L (CTSL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [24]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [91]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [92]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [93]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [94]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [97]
Verapamil DMA7PEW Angina pectoris BA40 Approved [51]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [99]
Selenium DM25CGV N. A. N. A. Approved [100]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [101]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Gefitinib DM15F0X Colon adenocarcinoma Approved [104]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [106]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [107]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [108]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [107]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [109]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [110]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
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Drug(s) Affected By Gap junction alpha-1 protein (GJA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [116]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [117]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [112]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [118]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [119]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [122]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [123]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [124]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [125]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [128]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [129]
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Drug(s) Affected By Caspase-4 (CASP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [52]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [133]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [134]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [22]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [135]
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Drug(s) Affected By Microsomal triglyceride transfer protein large subunit (MTTP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [136]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [136]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [136]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [136]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [137]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [138]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [139]
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Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [140]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [52]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [142]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [143]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [143]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [144]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [145]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [146]
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Drug(s) Affected By BH3-interacting domain death agonist (BID)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [106]
Selenium DM25CGV N. A. N. A. Approved [147]
Quercetin DM3NC4M Obesity 5B81 Approved [148]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [150]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [151]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [152]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
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Drug(s) Affected By BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [155]
Quinolones DM5GVHU Bacterial infection 1A00-1C4Z Approved [156]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [157]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [159]
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Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [160]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [161]
Gefitinib DM15F0X Colon adenocarcinoma Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [164]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
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Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [168]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [169]
Prednisone DM2HG4X Acute asthma CA23 Approved [170]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [170]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [171]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Epinephrine DM3KJBC Acute asthma CA23 Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [174]
Fluoxetine DM3PD2C Bipolar depression Approved [175]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [176]
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Drug(s) Affected By NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [15]
Selenium DM25CGV N. A. N. A. Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [178]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [181]
Ethanol DMDRQZU Chronic pain MG30 Approved [182]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [183]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [184]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [185]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [186]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [187]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [188]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [189]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [190]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [189]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [193]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [24]
Capsaicin DMGMF6V Back pain ME84.Z Approved [194]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [195]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [196]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [94]
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Drug(s) Affected By Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Clozapine DMFC71L Schizophrenia 6A20 Approved [198]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [94]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [200]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [201]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [202]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [203]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Vacuolar-type proton ATPase (v-ATPase) TTTK3BH NOUNIPROTAC Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [3]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Gene/Protein Processing [4]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Gene/Protein Processing [5]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Protein Interaction/Cellular Processes [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [5]
Caspase-4 (CASP4) OTVQTV1L CASP4_HUMAN Gene/Protein Processing [7]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [5]
Cathepsin D (CTSD) OTQZ36F3 CATD_HUMAN Protein Interaction/Cellular Processes [8]
Gap junction alpha-1 protein (GJA1) OTT94MKL CXA1_HUMAN Gene/Protein Processing [9]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Gene/Protein Processing [10]

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