DOT Name |
DOT ID |
UniProt ID |
Mode of Action |
REF |
Cytochrome P450 3A4 (CYP3A4)
|
OTQGYY83
|
CP3A4_HUMAN
|
Increases Expression
|
[14] |
CCN family member 1 (CCN1)
|
OTKJBEMD
|
CCN1_HUMAN
|
Increases Expression
|
[7] |
Phospholipid phosphatase 3 (PLPP3)
|
OTSSF7BK
|
PLPP3_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT3)
|
OTPGHZB9
|
IFIT3_HUMAN
|
Decreases Expression
|
[7] |
Calmegin (CLGN)
|
OTEWVFQV
|
CLGN_HUMAN
|
Decreases Expression
|
[7] |
D-3-phosphoglycerate dehydrogenase (PHGDH)
|
OT1LMRTG
|
SERA_HUMAN
|
Decreases Expression
|
[7] |
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2)
|
OT0KMIYQ
|
RIPK2_HUMAN
|
Decreases Expression
|
[7] |
Gasdermin-E (GSDME)
|
OT1ZWY32
|
GSDME_HUMAN
|
Decreases Expression
|
[7] |
Toll-like receptor 2 (TLR2)
|
OTGO5P4R
|
TLR2_HUMAN
|
Decreases Expression
|
[7] |
CCN family member 5 (CCN5)
|
OTADU8JJ
|
CCN5_HUMAN
|
Increases Expression
|
[7] |
Antiviral innate immune response receptor RIG-I (RIGI)
|
OTFIIC43
|
RIGI_HUMAN
|
Decreases Expression
|
[7] |
2'-5'-oligoadenylate synthase 1 (OAS1)
|
OT8ZLOCY
|
OAS1_HUMAN
|
Decreases Expression
|
[7] |
Collagen alpha-1(I) chain (COL1A1)
|
OTI31178
|
CO1A1_HUMAN
|
Increases Expression
|
[7] |
Superoxide dismutase , mitochondrial (SOD2)
|
OTIWXGZ9
|
SODM_HUMAN
|
Decreases Expression
|
[7] |
Ubiquitin-like protein ISG15 (ISG15)
|
OT53QQ7N
|
ISG15_HUMAN
|
Decreases Expression
|
[7] |
Interleukin-6 (IL6)
|
OTUOSCCU
|
IL6_HUMAN
|
Decreases Expression
|
[7] |
Thrombospondin-1 (THBS1)
|
OT0ECWK3
|
TSP1_HUMAN
|
Increases Expression
|
[7] |
Asparagine synthetase (ASNS)
|
OT8R922G
|
ASNS_HUMAN
|
Decreases Expression
|
[7] |
Hepatocyte growth factor receptor (MET)
|
OT7K55MU
|
MET_HUMAN
|
Decreases Expression
|
[7] |
Steryl-sulfatase (STS)
|
OTXTJQPC
|
STS_HUMAN
|
Increases Expression
|
[7] |
Neuromedin-B (NMB)
|
OT4NLN6H
|
NMB_HUMAN
|
Decreases Expression
|
[7] |
Stromelysin-2 (MMP10)
|
OTJDWW8Q
|
MMP10_HUMAN
|
Decreases Expression
|
[7] |
Growth-regulated alpha protein (CXCL1)
|
OT3WCTZV
|
GROA_HUMAN
|
Decreases Expression
|
[7] |
Interferon alpha-inducible protein 6 (IFI6)
|
OTWOOAM4
|
IFI6_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)
|
OTXOQDSG
|
IFIT1_HUMAN
|
Decreases Expression
|
[7] |
Interleukin-1 receptor antagonist protein (IL1RN)
|
OT308CBE
|
IL1RA_HUMAN
|
Decreases Expression
|
[7] |
C-X-C motif chemokine 2 (CXCL2)
|
OTEJCYMY
|
CXCL2_HUMAN
|
Decreases Expression
|
[7] |
C-X-C motif chemokine 3 (CXCL3)
|
OTSL94KH
|
CXCL3_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced GTP-binding protein Mx1 (MX1)
|
OT6X8G5T
|
MX1_HUMAN
|
Decreases Expression
|
[7] |
Fibulin-1 (FBLN1)
|
OT5MHHOP
|
FBLN1_HUMAN
|
Increases Expression
|
[7] |
Atypical chemokine receptor 3 (ACKR3)
|
OTA6GA4F
|
ACKR3_HUMAN
|
Decreases Expression
|
[7] |
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1)
|
OTO7FJA9
|
DHI1_HUMAN
|
Decreases Expression
|
[7] |
Adenosine receptor A2a (ADORA2A)
|
OTVRBZ0I
|
AA2AR_HUMAN
|
Decreases Expression
|
[7] |
CCN family member 2 (CCN2)
|
OTC39NSU
|
CCN2_HUMAN
|
Increases Expression
|
[7] |
Myristoylated alanine-rich C-kinase substrate (MARCKS)
|
OT7N056G
|
MARCS_HUMAN
|
Decreases Expression
|
[7] |
Guanylate-binding protein 1 (GBP1)
|
OTUM7RPJ
|
GBP1_HUMAN
|
Decreases Expression
|
[7] |
Prostaglandin G/H synthase 2 (PTGS2)
|
OT75U9M4
|
PGH2_HUMAN
|
Decreases Expression
|
[7] |
Macrophage metalloelastase (MMP12)
|
OT9Z7LHM
|
MMP12_HUMAN
|
Decreases Expression
|
[7] |
Interferon alpha-inducible protein 27, mitochondrial (IFI27)
|
OTI2XGIT
|
IFI27_HUMAN
|
Decreases Expression
|
[7] |
Regulator of G-protein signaling 4 (RGS4)
|
OTG94HHL
|
RGS4_HUMAN
|
Decreases Expression
|
[7] |
Prolargin (PRELP)
|
OT9EEBUJ
|
PRELP_HUMAN
|
Increases Expression
|
[7] |
Spermine synthase (SMS)
|
OT8JYKNH
|
SPSY_HUMAN
|
Decreases Expression
|
[7] |
C-X-C chemokine receptor type 4 (CXCR4)
|
OTUFSBX2
|
CXCR4_HUMAN
|
Decreases Expression
|
[7] |
C-C motif chemokine 20 (CCL20)
|
OTUCJY4N
|
CCL20_HUMAN
|
Decreases Expression
|
[7] |
DNA-binding protein inhibitor ID-3 (ID3)
|
OTUULW5Z
|
ID3_HUMAN
|
Increases Expression
|
[7] |
Tumor necrosis factor alpha-induced protein 2 (TNFAIP2)
|
OTRZH80H
|
TNAP2_HUMAN
|
Decreases Expression
|
[7] |
Aldehyde oxidase (AOX1)
|
OT2FZP6H
|
AOXA_HUMAN
|
Increases Expression
|
[7] |
Bone marrow stromal antigen 2 (BST2)
|
OTU4LCJV
|
BST2_HUMAN
|
Decreases Expression
|
[7] |
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)
|
OTZVUOOB
|
FBLN3_HUMAN
|
Increases Expression
|
[7] |
Neuronal membrane glycoprotein M6-b (GPM6B)
|
OT8Q1582
|
GPM6B_HUMAN
|
Increases Expression
|
[7] |
Laminin subunit beta-3 (LAMB3)
|
OTFPU6W8
|
LAMB3_HUMAN
|
Decreases Expression
|
[7] |
Nidogen-2 (NID2)
|
OTHC33FF
|
NID2_HUMAN
|
Increases Expression
|
[7] |
Signal transducer and activator of transcription 4 (STAT4)
|
OTAK3VFR
|
STAT4_HUMAN
|
Decreases Expression
|
[7] |
2'-5'-oligoadenylate synthase-like protein (OASL)
|
OTZ05YRP
|
OASL_HUMAN
|
Decreases Expression
|
[7] |
Bcl-2-related protein A1 (BCL2A1)
|
OTWRYSNA
|
B2LA1_HUMAN
|
Decreases Expression
|
[7] |
Lymphocyte antigen 6E (LY6E)
|
OTMG16BZ
|
LY6E_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced protein 44-like (IFI44L)
|
OTXKORJP
|
IF44L_HUMAN
|
Decreases Expression
|
[7] |
Olfactomedin-like protein 2B (OLFML2B)
|
OTDNJFR4
|
OLM2B_HUMAN
|
Increases Expression
|
[7] |
E3 ubiquitin-protein ligase RNF19B (RNF19B)
|
OTYCWKBP
|
RN19B_HUMAN
|
Decreases Expression
|
[7] |
Amphoterin-induced protein 2 (AMIGO2)
|
OTPAIT1O
|
AMGO2_HUMAN
|
Decreases Expression
|
[7] |
Probable E3 ubiquitin-protein ligase HERC6 (HERC6)
|
OT7G9PQE
|
HERC6_HUMAN
|
Decreases Expression
|
[7] |
Equilibrative nucleobase transporter 1 (SLC43A3)
|
OTR60ZLA
|
S43A3_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced protein 44 (IFI44)
|
OTOKSZVA
|
IFI44_HUMAN
|
Decreases Expression
|
[7] |
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (RSAD2)
|
OTCA9WCM
|
RSAD2_HUMAN
|
Decreases Expression
|
[7] |
Nuclear receptor subfamily 4 group A member 3 (NR4A3)
|
OTPBE9R1
|
NR4A3_HUMAN
|
Decreases Expression
|
[7] |
Type II iodothyronine deiodinase (DIO2)
|
OTGPNSLH
|
IOD2_HUMAN
|
Increases Expression
|
[7] |
Interferon regulatory factor 7 (IRF7)
|
OTC1A2PQ
|
IRF7_HUMAN
|
Decreases Expression
|
[7] |
Interferon-stimulated gene 20 kDa protein (ISG20)
|
OTCWRJJW
|
ISG20_HUMAN
|
Decreases Expression
|
[7] |
Interferon-induced helicase C domain-containing protein 1 (IFIH1)
|
OTZA2AHA
|
IFIH1_HUMAN
|
Decreases Expression
|
[7] |
Anthrax toxin receptor 1 (ANTXR1)
|
OT5W1GPC
|
ANTR1_HUMAN
|
Increases Expression
|
[7] |
Interleukin-23 subunit alpha (IL23A)
|
OTYO99HC
|
IL23A_HUMAN
|
Decreases Expression
|
[7] |
NADH dehydrogenase 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2)
|
OTK0PG7R
|
NUA4L_HUMAN
|
Decreases Expression
|
[7] |
Large neutral amino acids transporter small subunit 2 (SLC7A8)
|
OT8XXVO8
|
LAT2_HUMAN
|
Increases Expression
|
[7] |
E3 ISG15--protein ligase HERC5 (HERC5)
|
OTZ5PR39
|
HERC5_HUMAN
|
Decreases Expression
|
[7] |
Paired immunoglobulin-like type 2 receptor alpha (PILRA)
|
OTBE0PLF
|
PILRA_HUMAN
|
Decreases Expression
|
[7] |
Cystine/glutamate transporter (SLC7A11)
|
OTKJ6PXW
|
XCT_HUMAN
|
Decreases Expression
|
[7] |
Cytochrome P450 2S1 (CYP2S1)
|
OTKHX4RF
|
CP2S1_HUMAN
|
Decreases Expression
|
[15] |
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
|
OTCO26FV
|
HMCS1_HUMAN
|
Increases Expression
|
[8] |
Inactive phospholipase C-like protein 1 (PLCL1)
|
OTJL2C79
|
PLCL1_HUMAN
|
Increases Expression
|
[8] |
Cyclin-G2 (CCNG2)
|
OTII38K2
|
CCNG2_HUMAN
|
Increases Expression
|
[8] |
Programmed cell death protein 4 (PDCD4)
|
OTZ6NXUX
|
PDCD4_HUMAN
|
Increases Expression
|
[8] |
Kelch-like protein 24 (KLHL24)
|
OTWZSX5C
|
KLH24_HUMAN
|
Increases Expression
|
[8] |
Protein FAM200C (FAM200C)
|
OTZOXUEK
|
F200C_HUMAN
|
Increases Expression
|
[8] |
Arrestin domain-containing protein 3 (ARRDC3)
|
OTAKW7R9
|
ARRD3_HUMAN
|
Increases Expression
|
[8] |
Sulfiredoxin-1 (SRXN1)
|
OTYDBO4L
|
SRXN1_HUMAN
|
Increases Expression
|
[8] |
Cysteine-rich motor neuron 1 protein (CRIM1)
|
OTTZNV6Y
|
CRIM1_HUMAN
|
Increases Expression
|
[8] |
SLAM family member 5 (CD84)
|
OTAY5B0F
|
SLAF5_HUMAN
|
Increases Expression
|
[8] |
PDZ and LIM domain protein 1 (PDLIM1)
|
OT4EGCPG
|
PDLI1_HUMAN
|
Increases Expression
|
[16] |
Basic helix-loop-helix ARNT-like protein 1 (BMAL1)
|
OTMI12L2
|
BMAL1_HUMAN
|
Increases Expression
|
[17] |
Period circadian protein homolog 2 (PER2)
|
OTU2B1DJ
|
PER2_HUMAN
|
Decreases Expression
|
[17] |
Period circadian protein homolog 1 (PER1)
|
OTVQF3WX
|
PER1_HUMAN
|
Increases Expression
|
[17] |
Transforming growth factor beta-1 proprotein (TGFB1)
|
OTV5XHVH
|
TGFB1_HUMAN
|
Decreases Expression
|
[18] |
Tumor necrosis factor (TNF)
|
OT4IE164
|
TNFA_HUMAN
|
Increases Expression
|
[19] |
Interleukin-1 beta (IL1B)
|
OT0DWXXB
|
IL1B_HUMAN
|
Decreases Expression
|
[16] |
Albumin (ALB)
|
OTVMM513
|
ALBU_HUMAN
|
Increases Expression
|
[20] |
Serotransferrin (TF)
|
OT41PEMS
|
TRFE_HUMAN
|
Increases Expression
|
[20] |
Glucocorticoid receptor (NR3C1)
|
OTCI2YDI
|
GCR_HUMAN
|
Increases Activity
|
[21] |
Insulin-like growth factor I (IGF1)
|
OTIIZR61
|
IGF1_HUMAN
|
Decreases Response To Substance
|
[22] |
Interleukin-4 (IL4)
|
OTOXBWAU
|
IL4_HUMAN
|
Decreases Expression
|
[23] |
Interleukin-5 (IL5)
|
OTAFPSCO
|
IL5_HUMAN
|
Decreases Expression
|
[23] |
Mineralocorticoid receptor (NR3C2)
|
OT0F2V2Z
|
MCR_HUMAN
|
Increases Activity
|
[21] |
Interleukin-8 (CXCL8)
|
OTS7T5VH
|
IL8_HUMAN
|
Decreases Expression
|
[16] |
C-C motif chemokine 3 (CCL3)
|
OTW2H3ND
|
CCL3_HUMAN
|
Increases Expression
|
[9] |
C-C motif chemokine 4 (CCL4)
|
OT6B8P25
|
CCL4_HUMAN
|
Increases Expression
|
[9] |
C-C motif chemokine 2 (CCL2)
|
OTAD2HEL
|
CCL2_HUMAN
|
Decreases Expression
|
[9] |
Ganglioside GM2 activator (GM2A)
|
OTIRWZC0
|
SAP3_HUMAN
|
Increases Expression
|
[16] |
Nuclear receptor subfamily 1 group D member 1 (NR1D1)
|
OTJ38PTB
|
NR1D1_HUMAN
|
Decreases Expression
|
[17] |
C-X-C chemokine receptor type 2 (CXCR2)
|
OTISGW7L
|
CXCR2_HUMAN
|
Decreases Expression
|
[24] |
Long-chain-fatty-acid--CoA ligase 1 (ACSL1)
|
OTB06ESI
|
ACSL1_HUMAN
|
Increases Expression
|
[16] |
Growth/differentiation factor 5 (GDF5)
|
OTOV8S81
|
GDF5_HUMAN
|
Decreases Expression
|
[25] |
Tissue factor pathway inhibitor 2 (TFPI2)
|
OTZCRWOR
|
TFPI2_HUMAN
|
Decreases Expression
|
[16] |
Transcription factor SOX-9 (SOX9)
|
OTVDJFGN
|
SOX9_HUMAN
|
Decreases Expression
|
[16] |
D site-binding protein (DBP)
|
OTE0W7LN
|
DBP_HUMAN
|
Decreases Expression
|
[17] |
Cryptochrome-1 (CRY1)
|
OTTGAJT0
|
CRY1_HUMAN
|
Decreases Expression
|
[17] |
Mucin-16 (MUC16)
|
OTHPPE67
|
MUC16_HUMAN
|
Decreases Expression
|
[26] |
Lymphocyte antigen 96 (LY96)
|
OTN4HXA2
|
LY96_HUMAN
|
Decreases Expression
|
[16] |
DNA topoisomerase 1 (TOP1)
|
OT51O0CF
|
TOP1_HUMAN
|
Increases ADR
|
[27] |
Histone-lysine N-methyltransferase 2A (KMT2A)
|
OT9GLJI6
|
KMT2A_HUMAN
|
Decreases Response To Substance
|
[28] |
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2)
|
OTHF4H9U
|
DHI2_HUMAN
|
Increases Metabolism
|
[29] |
Mothers against decapentaplegic homolog 1 (SMAD1)
|
OTQSHR25
|
SMAD1_HUMAN
|
Increases ADR
|
[27] |
Catenin beta-1 (CTNNB1)
|
OTZ932A3
|
CTNB1_HUMAN
|
Increases ADR
|
[27] |
------------------------------------------------------------------------------------ |
|
|
|
|