Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0YHKB)

Drug Name
Acteoside Drug Info
Synonyms TJC-160
Indication
Disease Entry ICD 11 Status REF
Nephritis GB40 Terminated [1]
Cross-matching ID
PubChem CID
5281800
ChEBI ID
CHEBI:9953
CAS Number
CAS 61276-17-3
TTD Drug ID
DM0YHKB

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Discontinued Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Protein kinase C alpha (PRKCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [6]
Sotrastaurin acetate DME53YS Renal transplantation NE84 Phase 2 [7]
PMID28460551-Compound-3 DMA1FRM N. A. N. A. Patented [8]
ISIS 3521 DMZFS69 N. A. N. A. Discontinued in Phase 2 [9]
BALANOL DMDLN9E N. A. N. A. Terminated [10]
RO-320432 DMFZ1YW N. A. N. A. Terminated [11]
LY-317644 DMM20PI N. A. N. A. Terminated [12]
RO-316233 DMAGLPW Discovery agent N.A. Investigative [13]
4,5,6,7-tetrabromo-1H-benzo[d][1,2,3]triazole DMN9YOB Discovery agent N.A. Investigative [14]
CI-1040 DMF3DZX Discovery agent N.A. Investigative [15]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [16]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [17]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [18]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [21]
Quercetin DM3NC4M Obesity 5B81 Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [25]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Selenium DM25CGV N. A. N. A. Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [29]
Epinephrine DM3KJBC Acute asthma CA23 Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [31]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [32]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [33]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [34]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [35]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [36]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [36]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [38]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [39]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [42]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [43]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [44]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [45]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [46]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [47]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [48]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [49]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [50]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [51]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [52]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [53]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [51]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [54]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [56]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [57]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [58]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [59]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [63]
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Drug(s) Affected By C-X-C motif chemokine 10 (CXCL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [4]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [66]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [72]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [73]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [74]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [76]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Ethacrynic acid DM60QMR Edema MG29 Approved [77]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [78]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [79]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [80]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [28]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [82]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [48]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [83]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [50]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [84]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [85]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [28]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [83]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [87]
Gefitinib DM15F0X Colon adenocarcinoma Approved [88]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [84]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [89]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [90]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [91]
Quercetin DM3NC4M Obesity 5B81 Approved [4]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [92]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [93]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [94]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [96]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [97]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [98]
Gefitinib DM15F0X Colon adenocarcinoma Approved [99]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [100]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
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Drug(s) Affected By Aryl hydrocarbon receptor nuclear translocator (ARNT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [102]
Methotrexate DM2TEOL Anterior urethra cancer Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [104]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [105]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [107]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [58]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [108]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [109]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [110]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [93]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [111]
Paclitaxel DMLB81S Breast carcinoma Approved [112]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [113]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [92]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [96]
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Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [115]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [116]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [117]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [119]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [121]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [122]
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Drug(s) Affected By Mothers against decapentaplegic homolog 7 (SMAD7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [125]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [126]
Leflunomide DMR8ONJ Arthritis FA20 Approved [127]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [129]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [130]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [131]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [132]
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Drug(s) Affected By Zinc finger protein SNAI2 (SNAI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [136]
Testosterone DM7HUNW Hot flushes GA30 Approved [137]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [137]
Leflunomide DMR8ONJ Arthritis FA20 Approved [127]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
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Drug(s) Affected By Zinc finger protein SNAI1 (SNAI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [140]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [141]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [142]
Leflunomide DMR8ONJ Arthritis FA20 Approved [127]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [143]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [144]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [145]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [147]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [148]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [89]
Prednisone DM2HG4X Acute asthma CA23 Approved [149]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [150]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [151]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [152]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [153]
Gefitinib DM15F0X Colon adenocarcinoma Approved [154]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [157]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
Methotrexate DM2TEOL Anterior urethra cancer Approved [159]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [160]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
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Drug(s) Affected By High mobility group protein B1 (HMGB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [162]
Gefitinib DM15F0X Colon adenocarcinoma Approved [163]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [136]
Testosterone DM7HUNW Hot flushes GA30 Approved [137]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [167]
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Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [168]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [169]
Selenium DM25CGV N. A. N. A. Approved [170]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [171]
Methotrexate DM2TEOL Anterior urethra cancer Approved [172]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [173]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [174]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [175]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
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Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [176]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [177]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [178]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [179]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [120]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [181]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [182]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [184]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [185]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [187]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [188]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [189]
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Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [82]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [190]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [191]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [192]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [158]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Fluoxetine DM3PD2C Bipolar depression Approved [193]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [194]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [195]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [196]
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Drug(s) Affected By G1/S-specific cyclin-D2 (CCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [170]
Methotrexate DM2TEOL Anterior urethra cancer Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [197]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [199]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [200]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
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Drug(s) Affected By G1/S-specific cyclin-D3 (CCND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [202]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [204]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [205]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [206]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [125]
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Drug(s) Affected By TGF-beta receptor type-1 (TGFBR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Diazepam DM08E9O Alcohol withdrawal Approved [207]
Quercetin DM3NC4M Obesity 5B81 Approved [208]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [33]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [209]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [210]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [210]
Testosterone DM7HUNW Hot flushes GA30 Approved [211]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
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Drug(s) Affected By TGF-beta receptor type-2 (TGFBR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [207]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [212]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [213]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [214]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [215]
Testosterone DM7HUNW Hot flushes GA30 Approved [137]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [137]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [199]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [217]
Gefitinib DM15F0X Colon adenocarcinoma Approved [218]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [219]
Etretinate DM2CZFA Keratosis ED56 Approved [220]
Prednisone DM2HG4X Acute asthma CA23 Approved [221]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin-H2 D-isomerase (PTGDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Selenium DM25CGV N. A. N. A. Approved [187]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [214]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [224]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [225]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [226]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [109]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [153]
Gefitinib DM15F0X Colon adenocarcinoma Approved [55]
Prednisone DM2HG4X Acute asthma CA23 Approved [221]
Methotrexate DM2TEOL Anterior urethra cancer Approved [228]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [229]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [230]
Fluoxetine DM3PD2C Bipolar depression Approved [193]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin, aortic smooth muscle (ACTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [233]
Quercetin DM3NC4M Obesity 5B81 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [234]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [235]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [236]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [125]
Testosterone DM7HUNW Hot flushes GA30 Approved [137]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [237]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [137]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mothers against decapentaplegic homolog 3 (SMAD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [238]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [239]
Quercetin DM3NC4M Obesity 5B81 Approved [208]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [240]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [241]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [242]
Ethanol DMDRQZU Chronic pain MG30 Approved [243]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [244]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [114]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [184]
Selenium DM25CGV N. A. N. A. Approved [187]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [246]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [247]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [248]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [249]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [250]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Advanced glycosylation end product-specific receptor (AGER)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [247]
Testosterone DM7HUNW Hot flushes GA30 Approved [211]
TRIENTINE DMD2WPG Inborn error of metabolism 5C50-5C59 Approved [252]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [253]
Mebendazole DMO14SG Ascariasis 1F62 Approved [254]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [255]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [255]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [253]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [256]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mothers against decapentaplegic homolog 2 (SMAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Quercetin DM3NC4M Obesity 5B81 Approved [208]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [250]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [209]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [136]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [259]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [259]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [260]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADPH oxidase 1 (NOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [137]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [137]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [261]
Arsenic DMTL2Y1 N. A. N. A. Approved [262]
Dalcetrapib DMKNCVM Acute coronary syndrome BA41 Phase 3 [263]
Anacetrapib DMP2BFG Arteriosclerosis BD40 Phase 3 [263]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [264]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [263]
U0126 DM31OGF Discovery agent N.A. Investigative [265]
Nickel chloride DMI12Y8 Discovery agent N.A. Investigative [266]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Protein kinase C alpha (PRKCA) TTFJ8Q1 KPCA_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [3]
Advanced glycosylation end product-specific receptor (AGER) OTPY0IH7 RAGE_HUMAN Gene/Protein Processing [3]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Protein Interaction/Cellular Processes [4]
Aryl hydrocarbon receptor nuclear translocator (ARNT) OTMSIEZY ARNT_HUMAN Protein Interaction/Cellular Processes [4]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [4]
C-X-C motif chemokine 10 (CXCL10) OTTLQ6S0 CXL10_HUMAN Gene/Protein Processing [4]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [3]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [5]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Gene/Protein Processing [5]

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