Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4L0R7)

Drug Name
Maleic Acid Drug Info
Synonyms 2-(2-ethoxyethyl)-3-ethylbut-2-enedioic acid; 6309-80-4; AC1L5ZJW; CTK6G3643; CTK5B7536; DTXSID10285386; Maleic acid,(2-ethoxyethyl)ethyl- (8CI)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
444266
ChEBI ID
CHEBI:18300
CAS Number
CAS 110-16-7
TTD Drug ID
DM4L0R7

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Investigative Drug(s)
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Cytoplasmic aspartate aminotransferase (GOT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
aminooxyacetic acid DMHNDTW Discovery agent N.A. Investigative [3]
Drug(s) Targeting Trypanosoma Trypanothione reductase (Trypano TPR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [4]
Bivalirudin DMECRX1 Thrombocytopenia 3B64 Approved [5]
Flavin-Adenine Dinucleotide DM5S4GK Discovery agent N.A. Investigative [6]
CONESSINE DM4VYP0 Discovery agent N.A. Investigative [7]
1-(2'-chlorophenyl)penta-1,4-dien-3-one DMKTZSY Discovery agent N.A. Investigative [8]
CEPHARANTINE DMCE3NA Discovery agent N.A. Investigative [7]
Trypanothione DMDUGQ1 Discovery agent N.A. Investigative [6]
N-(5-chloro-2-(phenylthio)phenyl)butyramide DMHZ256 Discovery agent N.A. Investigative [9]
N1,N2-bis(dihydrocaffeoyl)spermine DMSDVGQ Discovery agent N.A. Investigative [7]
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Drug(s) Affected By TRPM8 channel-associated factor 2 (TCAF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [11]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [12]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [13]
Drug(s) Affected By Olfactory receptor 6C65 (OR6C65)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [15]
Drug(s) Affected By Putative claudin-25 (CLDN25)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [16]
Drug(s) Affected By 3-phosphoinositide-dependent protein kinase 1 (PDPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [17]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [20]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [21]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Amiloride DMRTSGP Congestive heart failure BD10 Approved [23]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [24]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [21]
Paclitaxel DMLB81S Breast carcinoma Approved [25]
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Drug(s) Affected By Nuclear factor of activated T-cells 5 (NFAT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [30]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [28]
Testosterone enanthate DMB6871 N. A. N. A. Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [32]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [33]
Sodium chloride DMM3950 Skin burns ME65.0 Approved [34]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [35]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [36]
Fructose DM43AN2 Vomiting MD90 Approved [37]
Ketoprofen DMRKXPT Bursitis Approved [37]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [38]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [39]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [40]
Gefitinib DM15F0X Colon adenocarcinoma Approved [41]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
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Drug(s) Affected By Insulin-like growth factor I (IGF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dantrolene DM1D8XY Hyperthermia MG26 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [47]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [49]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [50]
Testosterone DM7HUNW Hot flushes GA30 Approved [51]
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Drug(s) Affected By High affinity immunoglobulin gamma Fc receptor I (FCGR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [54]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [11]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [55]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
Rapamycin Immunosuppressant Drug DM678IB Discovery agent N.A. Investigative [53]
PHENCYCLIDINE DMQBEYX Discovery agent N.A. Investigative [56]
paraquat DMR8O3X Discovery agent N.A. Investigative [57]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complement receptor type 1 (CR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [58]
Methotrexate DM2TEOL Anterior urethra cancer Approved [59]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [60]
Josamycin DMKJ8LB Bacterial infection 1A00-1C4Z Approved [61]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [62]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [63]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [64]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gonadotropin-releasing hormone receptor (GNRHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [65]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [66]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [67]
Milchsaure DM462BT Pruritus EC90 Investigative [68]
1,6-hexamethylene diisocyanate DMLB3RT Discovery agent N.A. Investigative [69]
Drug(s) Affected By RAC-beta serine/threonine-protein kinase (AKT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [45]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [70]
Quercetin DM3NC4M Obesity 5B81 Approved [71]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [72]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [70]
Testosterone DM7HUNW Hot flushes GA30 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Menthol DMG2KW7 Back pain ME84.Z Approved [74]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [75]
Paclitaxel DMLB81S Breast carcinoma Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A3 (S100A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [15]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [72]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [20]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione hydrolase 5 proenzyme (GGT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [18]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Fluticasone propionate DMRWLB2 Allergic asthma CA23.0 Approved [82]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
Beclomethasone dipropionate DM5NW1E Allergic rhinitis CA08.0 Phase 4 [82]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [86]
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Drug(s) Affected By Glutamate receptor 1 (GRIA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [87]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [88]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [89]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [90]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [92]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [93]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Potassium voltage-gated channel subfamily C member 1 (KCNC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Panobinostat DM58WKG Chronic graft versus host disease Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Arsenic DMTL2Y1 N. A. N. A. Approved [94]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [15]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [95]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Histone H2B type 1-C/E/F/G/I (H2BC10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [97]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [33]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [20]
Ethanol DMDRQZU Chronic pain MG30 Approved [100]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Flavin-containing monooxygenase 1 (FMO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [102]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [103]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [104]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Dihydroxyacetone DMM1LG2 Sunburn EJ40 Approved [106]
Atazanavir DMSYRBX Human immunodeficiency virus infection 1C62 Approved [105]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [107]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spermatogenesis-associated protein 1 (SPATA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Urethane DM7NSI0 N. A. N. A. Phase 4 [108]
Drug(s) Affected By Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [19]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [79]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [112]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [60]
Nitrobenzanthrone DMN6L70 N. A. N. A. Investigative [113]
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Drug(s) Affected By Solute carrier family 25 member 48 (SLC25A48)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [114]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [115]
Drug(s) Affected By N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 (B4GALNT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
Arsenic DMTL2Y1 N. A. N. A. Approved [94]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
Urethane DM7NSI0 N. A. N. A. Phase 4 [108]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [117]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [15]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [118]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Src kinase-associated phosphoprotein 1 (SKAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [119]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [122]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [123]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [124]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid-transporting ATPase ABCA7 (ABCA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [126]
Testosterone DM7HUNW Hot flushes GA30 Approved [16]
Testosterone enanthate DMB6871 N. A. N. A. Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Paclitaxel DMLB81S Breast carcinoma Approved [127]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spermatid maturation protein 1 (SPEM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
Drug(s) Affected By EF-hand calcium-binding domain-containing protein 4A (CRACR2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [70]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [128]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [79]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
Arsenic DMTL2Y1 N. A. N. A. Approved [129]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
Urethane DM7NSI0 N. A. N. A. Phase 4 [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Olfactory receptor 11G2 (OR11G2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
Drug(s) Affected By Polycystin-1-like protein 1 (PKD1L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [15]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [24]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [15]
Drug(s) Affected By GRB2-associated-binding protein 3 (GAB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [11]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [117]
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Drug(s) Affected By Uncharacterized protein C20orf173 (C20ORF173)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Drug(s) Affected By Sperm protein associated with the nucleus on the X chromosome D (SPANXD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [99]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [80]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [130]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [131]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [132]
Drug(s) Affected By Radial spoke head protein 6 homolog A (RSPH6A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [24]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [63]
Drug(s) Affected By Protocadherin alpha-C1 (PCDHAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [117]
Drug(s) Affected By Transcription factor SOX-17 (SOX17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [133]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [133]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [133]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [133]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [78]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [133]
Ziprasidone DMM58JY Bipolar disorder 6A60 Approved [133]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 40 (FBXO40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone enanthate DMB6871 N. A. N. A. Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [62]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [85]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [117]
Drug(s) Affected By Protein FAM153A (FAM153A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [135]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [136]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [135]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [137]
Urethane DM7NSI0 N. A. N. A. Phase 4 [108]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [14]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [15]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [10]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [138]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [139]
Urethane DM7NSI0 N. A. N. A. Phase 4 [108]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cytoplasmic aspartate aminotransferase (GOT1) TTU507L AATC_HUMAN Inhibitor [1]
Trypanosoma Trypanothione reductase (Trypano TPR) TTRTKPV TYTR_TRYBB Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3-phosphoinositide-dependent protein kinase 1 (PDPK1) OTT09ZVP PDPK1_HUMAN Gene/Protein Processing [2]
5'-3' DNA helicase ZGRF1 OTFPSF6A ZGRF1_HUMAN Gene/Protein Processing [2]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) OTVX8835 AGAP1_HUMAN Gene/Protein Processing [2]
Collagen and calcium-binding EGF domain-containing protein 1 (CCBE1) OTO4UIDB CCBE1_HUMAN Gene/Protein Processing [2]
Complement receptor type 1 (CR1) OTODWRW4 CR1_HUMAN Gene/Protein Processing [2]
EF-hand calcium-binding domain-containing protein 4A (CRACR2B) OT8L843R EFC4A_HUMAN Gene/Protein Processing [2]
F-box only protein 40 (FBXO40) OTS62YA2 FBX40_HUMAN Gene/Protein Processing [2]
Flavin-containing monooxygenase 1 (FMO1) OTTHSQKP FMO1_HUMAN Gene/Protein Processing [2]
Glutamate receptor 1 (GRIA1) OT85LOCJ GRIA1_HUMAN Gene/Protein Processing [2]
Glutathione hydrolase 5 proenzyme (GGT5) OTDJYEO7 GGT5_HUMAN Gene/Protein Processing [2]

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137 Progesterone regulation of implantation-related genes: new insights into the role of oestrogen. Cell Mol Life Sci. 2007 Apr;64(7-8):1009-32.
138 Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation. PLoS One. 2012;7(12):e53003. doi: 10.1371/journal.pone.0053003. Epub 2012 Dec 27.
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