General Information of Drug (ID: DM56YN7)

Drug Name
Desloratadine Drug Info
Synonyms
Aerius; Allex; Azomyr; Claramax; Clarinex; Denosin; Desalex; Descarboethoxyloratadine; Descarboethoxyoratidine; Desloratidine; Neoclarityn; Opulis; Clarinex RediTabs; Desloratadine [USAN]; Essex brand of desloratadine; Schering brand of desloratadine; Sch 34117; Aerius (TN); Claramax (TN); Clarinex (TN); NeoClarityn (TN); Sch-34117; Schering-Plough brand of desloratadine; Desloratadine (USAN/INN); 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine; 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Indication
Disease Entry ICD 11 Status REF
Allergic rhinitis CA08.0 Approved [1]
Common cold CA00 Approved [2]
Seasonal allergic rhinitis CA08.01 Approved [2]
Vasomotor/allergic rhinitis CA08 Approved [2]
Allergic urticaria Investigative [2]
Therapeutic Class
Antiallergic Agents
Cross-matching ID
PubChem CID
124087
ChEBI ID
CHEBI:291342
CAS Number
CAS 100643-71-8
TTD Drug ID
DM56YN7
VARIDT Drug ID
DR00497
INTEDE Drug ID
DR1761
ACDINA Drug ID
D00180

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Drug(s) Targeting Histamine H1 receptor (H1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [10]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [11]
Azelastine DMXTMBJ Allergic conjunctivitis 9A60.02 Approved [12]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [13]
Cinnarizine DM7U5QJ Meniere disease AB31.0 Approved [14]
Diphenhydramine DMKQTBA Hyperemesis gravidarum Approved [12]
Doxepin DMPI98T Anxiety Approved [15]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [12]
Epinastine DMX0K3Q Allergic conjunctivitis 9A60.02 Approved [16]
Tranilast DME5Y64 Allergic rhinitis CA08.0 Approved [17]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [18]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Folic Acid DMEMBJC Colorectal carcinoma Approved [21]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [20]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [22]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [20]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [23]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [24]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [25]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [26]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [26]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [27]
Verapamil DMA7PEW Angina pectoris BA40 Approved [28]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [29]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [30]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [26]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [31]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [32]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Pizotyline DMV74ZH Headache 8A80-8A84 Approved [33]
Cotinine DMCEZ1B Insecticide N.A. Approved [34]
Drug(s) Affected By Histamine H1 receptor (HRH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [9]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Clozapine DMFC71L Schizophrenia 6A20 Approved [41]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [42]
Olanzapine DMPFN6Y Bipolar depression Approved [41]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [47]
Etretinate DM2CZFA Keratosis ED56 Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [52]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Gefitinib DM15F0X Colon adenocarcinoma Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [56]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [57]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [58]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [57]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [59]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [60]
Methotrexate DM2TEOL Anterior urethra cancer Approved [61]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [62]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [63]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [64]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [65]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Verapamil DMA7PEW Angina pectoris BA40 Approved [66]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [67]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [69]
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Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [70]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [73]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [75]
Fructose DM43AN2 Vomiting MD90 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [71]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [78]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [43]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [44]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [79]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [47]
Etretinate DM2CZFA Keratosis ED56 Approved [48]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [58]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [80]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [81]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [85]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [87]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [88]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [91]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [92]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [93]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [94]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [95]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [96]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [97]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [99]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [100]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [101]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [69]
Selenium DM25CGV N. A. N. A. Approved [83]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [49]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [103]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [105]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [107]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [108]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [109]
Quinidine DMLPICK N. A. N. A. Approved [110]
Verapamil DMA7PEW Angina pectoris BA40 Approved [111]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [112]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [112]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [113]
Propranolol DM79NTF Angina pectoris BA40 Approved [114]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [115]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [116]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [112]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Captopril DM458UM Chronic heart failure BD1Z Approved [117]
Diazepam DM08E9O Alcohol withdrawal Approved [118]
Dantrolene DM1D8XY Hyperthermia MG26 Approved [118]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [118]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [118]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [118]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [118]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [118]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [118]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [85]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [120]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [88]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [121]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [122]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [123]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [122]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [124]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [125]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [127]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [128]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [130]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [131]
Capsaicin DMGMF6V Back pain ME84.Z Approved [132]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [133]
Quinidine DMLPICK N. A. N. A. Approved [134]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [135]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histamine H1 receptor (H1R) TTTIBOJ HRH1_HUMAN Antagonist [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [5]
UDP-glucuronosyltransferase 2B10 (UGT2B10) DEI8NGH UDB10_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Angiotensin-converting enzyme 2 (ACE2) OTTRZGU7 ACE2_HUMAN Protein Interaction/Cellular Processes [6]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [7]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [7]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Post-Translational Modifications [7]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Biotransformations [8]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Gene/Protein Processing [7]
Glycylpeptide N-tetradecanoyltransferase 1 (NMT1) OT42GQ3D NMT1_HUMAN Drug Response [7]
Hippocalcin-like protein 1 (HPCAL1) OTOBBFRD HPCL1_HUMAN Gene/Protein Processing [7]
Histamine H1 receptor (HRH1) OT8F9FV6 HRH1_HUMAN Protein Interaction/Cellular Processes [9]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Protein Interaction/Cellular Processes [7]

References

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2 Desloratadine FDA Label
3 Examining the tolerability of the non-sedating antihistamine desloratadine: a prescription-event monitoring study in England. Drug Saf. 2009;32(2):169-79.
4 P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists. Drug Metab Dispos. 2003 Mar;31(3):312-8.
5 Further characterization of the metabolism of desloratadine and its cytochrome P450 and UDP-glucuronosyltransferase inhibition potential: identification of desloratadine as a relatively selective UGT2B10 inhibitor. Drug Metab Dispos. 2015 Sep;43(9):1294-302.
6 Testing of the inhibitory effects of loratadine and desloratadine on SARS-CoV-2 spike pseudotyped virus viropexis. Chem Biol Interact. 2021 Apr 1;338:109420. doi: 10.1016/j.cbi.2021.109420. Epub 2021 Feb 18.
7 Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression. Signal Transduct Target Ther. 2023 Jan 9;8(1):14. doi: 10.1038/s41392-022-01248-9.
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9 Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5591-4.
10 Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol. 2001 Mar;59(3):420-6.
11 Clinical research of Ibudilast on treating the steroid resistant allergic rhinitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Jan;23(2):63-6.
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16 Influence of epinastine hydrochloride, an H1-receptor antagonist, on the function of mite allergen-pulsed murine bone marrow-derived dendritic cell... Mediators Inflamm. 2009;2009:738038.
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19 MDR1 (ABCB1) G1199A (Ser400Asn) polymorphism alters transepithelial permeability and sensitivity to anticancer agents. Cancer Chemother Pharmacol. 2009 Jun;64(1):183-8.
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21 Folate transporter expression decreases in the human placenta throughout pregnancy and in pre-eclampsia. Pregnancy Hypertens. 2012 Apr;2(2):123-31.
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24 Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia. Ther Drug Monit. 2011 Apr;33(2):244-50.
25 Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes. Drug Metab Dispos. 2000 Dec;28(12):1457-63.
26 Role of cytochrome P450 2C8 in drug metabolism and interactions. Pharmacol Rev. 2016 Jan;68(1):168-241.
27 Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.
28 Differential expression and function of CYP2C isoforms in human intestine and liver. Pharmacogenetics. 2003 Sep;13(9):565-75.
29 Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants. Biochemistry. 2004 Dec 14;43(49):15379-92.
30 Interaction of sorafenib and cytochrome P450 isoenzymes in patients with advanced melanoma: a phase I/II pharmacokinetic interaction study. Cancer Chemother Pharmacol. 2011 Nov;68(5):1111-8.
31 PharmGKB summary: mycophenolic acid pathway. Pharmacogenet Genomics. 2014 Jan;24(1):73-9.
32 Possible involvement of multiple human cytochrome P450 isoforms in the liver metabolism of propofol. Br J Anaesth. 1998 Jun;80(6):788-95.
33 Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4. Drug Metab Dispos. 2013 Jul;41(7):1389-97.
34 Human UDP-glucuronosyltransferase (UGT) 2B10: validation of cotinine as a selective probe substrate, inhibition by UGT enzyme-selective inhibitors and antidepressant and antipsychotic drugs, and structural determinants of enzyme inhibition. Drug Metab Dispos. 2016 Mar;44(3):378-88.
35 ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899.
36 Cannabidiol Activates Neuronal Precursor Genes in Human Gingival Mesenchymal Stromal Cells. J Cell Biochem. 2017 Jun;118(6):1531-1546. doi: 10.1002/jcb.25815. Epub 2016 Dec 29.
37 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
38 Integrated analysis of rifampicin-induced microRNA and gene expression changes in human hepatocytes. Drug Metab Pharmacokinet. 2014;29(4):333-40.
39 Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification. Toxicol Sci. 2010 May;115(1):66-79.
40 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
41 No evidence for binding of clozapine, olanzapine and/or haloperidol to selected receptors involved in body weight regulation. Pharmacogenomics J. 2007 Aug;7(4):275-81. doi: 10.1038/sj.tpj.6500418. Epub 2006 Sep 19.
42 Mitochondrial Uncoupling Induces Epigenome Remodeling and Promotes Differentiation in Neuroblastoma. Cancer Res. 2023 Jan 18;83(2):181-194. doi: 10.1158/0008-5472.CAN-22-1029.
43 Cannabidiol-induced transcriptomic changes and cellular senescence in human Sertoli cells. Toxicol Sci. 2023 Feb 17;191(2):227-238. doi: 10.1093/toxsci/kfac131.
44 G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently. J Biol Chem. 1993 Apr 15;268(11):8298-308.
45 mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels. Cancer Sci. 2008 Oct;99(10):1992-2003. doi: 10.1111/j.1349-7006.2008.00955.x.
46 Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol Sci. 2010 Apr;114(2):193-203. doi: 10.1093/toxsci/kfp309. Epub 2009 Dec 31.
47 Selenite and selenomethionine promote HL-60 cell cycle progression. J Nutr. 2002 Apr;132(4):674-9. doi: 10.1093/jn/132.4.674.
48 Bexarotene activates the p53/p73 pathway in human cutaneous T-cell lymphoma. Br J Dermatol. 2009 Mar;160(3):519-26. doi: 10.1111/j.1365-2133.2008.08931.x. Epub 2008 Nov 25.
49 Differential gene expression of sulindac-treated human breast epithelial cells. Int J Oncol. 2005 Dec;27(6):1727-36.
50 Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. Tumour Biol. 2011 Oct;32(5):965-76.
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