Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZVS9Y)

Drug Name
OXYQUINOLINE Drug Info
Synonyms
8-HYDROXYQUINOLINE; quinolin-8-ol; 8-quinolinol; 148-24-3; Oxyquinoline; Oxine; Quinophenol; 8-Quinol; 8-Oxyquinoline; Phenopyridine; Oxychinolin; Bioquin; Oxybenzopyridine; Oxin; Hydroxybenzopyridine; 1-Azanaphthalene-8-ol; Tumex; 8-Chinolinol; 8-Hydroxychinolin; 8-OQ; 8-Hydroxy-chinolin; Fennosan H 30; Fennosan; o-Oxychinolin; 8-Oxychinolin; Usaf ek-794; Fennosan HF-15; NCI-C55298; NSC 2039; Oxyquinoline [USAN]; Caswell No. 719; Oxoquinoline; 8-Chinolinol [Czech]; o-Oxychinolin [German]; Quinoline, 8-hydroxy-; NSC 615011; UNII-5UTX5635HP
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
1923
ChEBI ID
CHEBI:48981
CAS Number
CAS 148-24-3
TTD Drug ID
DMZVS9Y

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Methionine aminopeptidase 2 (METAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beloranib DM71CK8 Solid tumour/cancer 2A00-2F9Z Phase 3 [3]
D-Methionine DMMKGBP N. A. N. A. Phase 3 [4]
ZGN-1061 DM9KB7A Type 2 diabetes 5A11 Phase 2 [5]
M8891 DMZ9NVP Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
SDX-7320 DMU0Q6L Solid tumour/cancer 2A00-2F9Z Phase 1 [6]
PPI-2458 DMSAQBC Autoimmune diabetes 5A10 Phase 1 [7]
TNP-470 DMT0QK8 Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [8]
2-Methyl-2-Propanol DMHM5GJ Discovery agent N.A. Investigative [4]
2-(phenylsulfonamido)-5-propylbenzoic acid DMDGAHO Discovery agent N.A. Investigative [9]
5-p-Tolyl-1H-[1,2,3]triazole DM2W0AD Discovery agent N.A. Investigative [10]
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Drug(s) Affected By Transcription factor E2F8 (E2F8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
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Drug(s) Affected By Golgin subfamily A member 8A (GOLGA8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [24]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
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Drug(s) Affected By EF-hand calcium-binding domain-containing protein 7 (EFCAB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [27]
Paclitaxel DMLB81S Breast carcinoma Approved [27]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [27]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
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Drug(s) Affected By Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
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Drug(s) Affected By Phospholemman (FXYD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [40]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [41]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
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Drug(s) Affected By Cell division cycle 7-related protein kinase (CDC7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [47]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [48]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [50]
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Drug(s) Affected By CCN family member 1 (CCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [55]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
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Drug(s) Affected By Class E basic helix-loop-helix protein 40 (BHLHE40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [58]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
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Drug(s) Affected By Calmegin (CLGN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [52]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [63]
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Drug(s) Affected By Monocarboxylate transporter 7 (SLC16A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [68]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [69]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
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Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [72]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [73]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [74]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [75]
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Drug(s) Affected By Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [78]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [81]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [82]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [83]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [81]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [82]
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Drug(s) Affected By Vinexin (SORBS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [90]
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Drug(s) Affected By Polycomb protein EED (EED)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [91]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [93]
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Drug(s) Affected By Solute carrier family 22 member 3 (SLC22A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [94]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [94]
Norepinephrine DMOUC09 Alopecia ED70 Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [95]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [97]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [98]
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Drug(s) Affected By Cytosolic 10-formyltetrahydrofolate dehydrogenase (ALDH1L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [100]
Folic Acid DMEMBJC Colorectal carcinoma Approved [101]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
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Drug(s) Affected By Ribosomal L1 domain-containing protein 1 (RSL1D1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [69]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
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Drug(s) Affected By Delta(14)-sterol reductase TM7SF2 (TM7SF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [34]
Capsaicin DMGMF6V Back pain ME84.Z Approved [106]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [105]
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Drug(s) Affected By Transmembrane and coiled-coil domains protein 1 (TMCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
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Drug(s) Affected By Protein FAM13A (FAM13A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Ethanol DMDRQZU Chronic pain MG30 Approved [111]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [112]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [113]
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Drug(s) Affected By Fatty acid CoA ligase Acsl3 (ACSL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [114]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Capsaicin DMGMF6V Back pain ME84.Z Approved [106]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [116]
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Drug(s) Affected By G1/S-specific cyclin-E2 (CCNE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [122]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [123]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [69]
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Drug(s) Affected By Cystatin-A (CSTA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [124]
Selenium DM25CGV N. A. N. A. Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [126]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [128]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Verapamil DMA7PEW Angina pectoris BA40 Approved [130]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [130]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [124]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [135]
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Drug(s) Affected By 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [136]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [137]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [138]
Digoxin DMQCTIH Arrhythmia BC9Z Approved [139]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [114]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metallothionein-1F (MT1F)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arginase-1 (ARG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [147]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [148]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [149]
Methotrexate DM2TEOL Anterior urethra cancer Approved [150]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [151]
Quercetin DM3NC4M Obesity 5B81 Approved [152]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [153]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [47]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thyroxine-binding globulin (SERPINA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leuprolide DM5XPIJ Plasma cell myeloma 2A83.1 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [156]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By All-trans-retinol dehydrogenase ADH4 (ADH4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [56]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [157]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [158]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-like growth factor-binding protein 1 (IGFBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [159]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [160]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [161]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [59]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [162]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [164]
Verapamil DMA7PEW Angina pectoris BA40 Approved [165]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [166]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [167]
Selenium DM25CGV N. A. N. A. Approved [168]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [169]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [170]
Methotrexate DM2TEOL Anterior urethra cancer Approved [171]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small integral membrane protein 13 (SMIM13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [97]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [173]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [174]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [175]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [176]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [177]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [178]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [180]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metallothionein-1G (MT1G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Farnesyl pyrophosphate synthase (FDPS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [182]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Clozapine DMFC71L Schizophrenia 6A20 Approved [184]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Galectin-3 (LGALS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [185]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [186]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [186]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-like growth factor-binding protein 3 (IGFBP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Selenium DM25CGV N. A. N. A. Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [188]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [189]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [58]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gastricsin (PGC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (AGA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [192]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Parathymosin (PTMS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [132]
Selenium DM25CGV N. A. N. A. Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [195]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [195]
Ethacrynic acid DM60QMR Edema MG29 Approved [197]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [198]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [195]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc-alpha-2-glycoprotein (AZGP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [97]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [200]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [201]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stomatin (STOM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [202]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [202]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [202]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein-lysine 6-oxidase (LOX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [148]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [204]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ethanol DMDRQZU Chronic pain MG30 Approved [111]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor HIVEP2 (HIVEP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [206]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanylate-binding protein 2 (GBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-adrenomedullin (ADM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [207]
Methotrexate DM2TEOL Anterior urethra cancer Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [209]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [210]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [68]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucose-6-phosphatase catalytic subunit 1 (G6PC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [213]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [211]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [68]
Leflunomide DMR8ONJ Arthritis FA20 Approved [214]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [56]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [122]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [215]
Gefitinib DM15F0X Colon adenocarcinoma Approved [216]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [217]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Etretinate DM2CZFA Keratosis ED56 Approved [218]
Prednisone DM2HG4X Acute asthma CA23 Approved [219]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [220]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 receptor subunit beta (IL6ST)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [223]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [224]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [224]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histidine ammonia-lyase (HAL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [226]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
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Drug(s) Affected By Tyrosine-protein kinase FRK (FRK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [227]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
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Drug(s) Affected By ETS translocation variant 4 (ETV4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [228]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Bortezomib DMNO38U Leukemia Approved [229]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [230]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [174]
Selenium DM25CGV N. A. N. A. Approved [76]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [231]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [232]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [233]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [58]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [235]
Diazepam DM08E9O Alcohol withdrawal Approved [236]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [237]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [235]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [238]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [235]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [239]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
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Drug(s) Affected By Protein HIRA (HIRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [240]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [241]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [20]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [26]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [242]
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Drug(s) Affected By Epithelial membrane protein 3 (EMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [202]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [202]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
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Drug(s) Affected By Mesencephalic astrocyte-derived neurotrophic factor (MANF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [245]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
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Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [81]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [83]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [81]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [81]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [82]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [81]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
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Drug(s) Affected By Myelin proteolipid protein (PLP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [247]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [248]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [248]
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Drug(s) Affected By Histone H2B type 1-C/E/F/G/I (H2BC10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Ethanol DMDRQZU Chronic pain MG30 Approved [111]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcineurin subunit B type 1 (PPP3R1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Bortezomib DMNO38U Leukemia Approved [229]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [251]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [139]
Sirolimus DMGW1ID Advanced cancer 2A00-2F9Z Approved [139]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [139]
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Drug(s) Affected By Arginase-2, mitochondrial (ARG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Selenium DM25CGV N. A. N. A. Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [252]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepcidin (HAMP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [185]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [253]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [254]
Papaverine DMCA9QP Brain ischaemia 8B1Z Approved [254]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ethanol DMDRQZU Chronic pain MG30 Approved [255]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-3 (ID3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [164]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [256]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [240]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [257]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [52]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aminoacylase-1 (ACY1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [259]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [260]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [235]
Diazepam DM08E9O Alcohol withdrawal Approved [236]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [261]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [235]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [235]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [262]
Ethacrynic acid DM60QMR Edema MG29 Approved [261]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [235]
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Drug(s) Affected By Sulfotransferase 2A1 (SULT2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [189]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [189]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [263]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [264]
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Drug(s) Affected By 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [265]
Calcidiol DMN4CV5 Hypophosphatemia Approved [266]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [267]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [268]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
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Drug(s) Affected By DnaJ homolog subfamily C member 3 (DNAJC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [270]
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Drug(s) Affected By Glucokinase regulatory protein (GCKR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [271]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [272]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [273]
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Drug(s) Affected By Growth factor receptor-bound protein 7 (GRB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [189]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [189]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [250]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [189]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [274]
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Drug(s) Affected By kinase isozyme 1, mitochondrial (PDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [69]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [252]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [275]
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Drug(s) Affected By Platelet-derived growth factor receptor-like protein (PDGFRL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
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Drug(s) Affected By Ankyrin repeat domain-containing protein 1 (ANKRD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ethanol DMDRQZU Chronic pain MG30 Approved [276]
Folic Acid DMEMBJC Colorectal carcinoma Approved [277]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
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Drug(s) Affected By SCL-interrupting locus protein (STIL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [278]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [48]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
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Drug(s) Affected By Sperm surface protein Sp17 (SPA17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
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Drug(s) Affected By Methylsterol monooxygenase 1 (MSMO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [114]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [57]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
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Drug(s) Affected By Glutaminyl-peptide cyclotransferase (QPCT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [279]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [280]
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Drug(s) Affected By Kynurenine--oxoglutarate transaminase 1 (KYAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [271]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [32]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [281]
L-methionine DME8G1U Discovery agent N.A. Investigative [282]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lanosterol 14-alpha demethylase (CYP51A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [283]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [284]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [64]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine dioxygenase type 1 (CDO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [285]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho GTPase-activating protein 44 (ARHGAP44)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [286]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [287]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [32]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Intestine-specific homeobox (ISX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Filamin A-interacting protein 1-like (FILIP1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [288]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [289]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiomotin (AMOT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spindlin-4 (SPIN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [290]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 128 (TMEM128)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
Milchsaure DM462BT Pruritus EC90 Investigative [291]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RNFT1 (RNFT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [292]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [293]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By EGF domain-specific O-linked N-acetylglucosamine transferase (EOGT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [34]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [34]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coiled-coil domain-containing protein 18 (CCDC18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [294]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein furry homolog (FRY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Bortezomib DMNO38U Leukemia Approved [229]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [295]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable E3 ubiquitin-protein ligase HECTD2 (HECTD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Bortezomib DMNO38U Leukemia Approved [229]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [296]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [297]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [34]
RESORCINOL DMM37C0 Discovery agent N.A. Investigative [49]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein fantom (RPGRIP1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [298]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [32]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HAUS augmin-like complex subunit 3 (HAUS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [299]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [251]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RPA-related protein RADX (RADX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [295]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Receptor expression-enhancing protein 3 (REEP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [294]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [293]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [173]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Parafibromin (CDC73)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Paclitaxel DMLB81S Breast carcinoma Approved [300]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [301]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [93]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BTB/POZ domain-containing protein KCTD18 (KCTD18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Progestin and adipoQ receptor family member 3 (PAQR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lipocalin-15 (LCN15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [302]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [272]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiopoietin-like protein 8 (ANGPTL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [2]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Calcium/manganese antiporter SLC30A10 (SLC30A10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [303]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [304]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Patched domain-containing protein 4 (PTCHD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Arsenic DMTL2Y1 N. A. N. A. Approved [305]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [306]
Lucanthone DMZLBUO Solid tumour/cancer 2A00-2F9Z Approved [307]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acyl-CoA dehydrogenase family member 11 (ACAD11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [308]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carbohydrate sulfotransferase 15 (CHST15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HEAT repeat-containing protein 3 (HEATR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin repeat domain-containing protein 37 (ANKRD37)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [2]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol-glycan biosynthesis class W protein (PIGW)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [296]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic solute transporter subunit alpha (SLC51A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [309]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [303]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [309]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydrofolate reductase 2, mitochondrial (DHFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [296]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [310]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CREB3 regulatory factor (CREBRF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [311]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [36]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cap-specific mRNA (CMTR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [312]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Adenylosuccinate synthetase isozyme 1 (ADSS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein S (CENPS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [128]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Paclitaxel DMLB81S Breast carcinoma Approved [300]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [292]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Translation factor GUF1, mitochondrial (GUF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [293]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BPI fold-containing family B member 2 (BPIFB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [272]
Drug(s) Affected By Carnosine N-methyltransferase (CARNMT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Intraflagellar transport protein 70B (IFT70B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [295]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxypeptidase A6 (CPA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [313]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [314]
NAPQI DM8F5LR Autoimmune disease 4A40-4A45 Investigative [315]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By DNA damage-regulated autophagy modulator protein 1 (DRAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [171]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [316]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Testis-expressed protein 9 (TEX9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [317]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [34]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein FAM241A (FAM241A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [56]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [24]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [318]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitoguardin 1 (MIGA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [34]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [2]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [319]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [26]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Transmembrane protein 116 (TMEM116)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [292]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM13C (FAM13C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [34]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch repeat and BTB domain-containing protein 8 (KBTBD8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [299]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Major facilitator superfamily domain-containing protein 8 (MFSD8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Clathrin heavy chain linker domain-containing protein 1 (CLHC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Endonuclease 8-like 3 (NEIL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [19]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ganglioside-induced differentiation-associated protein 1 (GDAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [40]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [173]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Ethanolamine-phosphate phospho-lyase (ETNPPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [320]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [34]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [271]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid phosphatase-related protein type 1 (PLPPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [286]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
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Drug(s) Affected By Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8L3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [158]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [322]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [2]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [173]
2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE DMNQL17 Discovery agent N.A. Investigative [323]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Probable glutathione peroxidase 8 (GPX8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Orlistat DMRJSP8 Obesity 5B81 Approved [324]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione-specific gamma-glutamylcyclotransferase 2 (CHAC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [325]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pentatricopeptide repeat-containing protein 2, mitochondrial (PTCD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [326]
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Drug(s) Affected By Cytoglobin (CYGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [327]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Arsenic DMTL2Y1 N. A. N. A. Approved [328]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Palladin (PALLD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Selenium DM25CGV N. A. N. A. Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aquaporin-3 (AQP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [329]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein NDRG1 (NDRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [279]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [330]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [331]
Quercetin DM3NC4M Obesity 5B81 Approved [332]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amyloid beta precursor protein binding family B member 2 (APBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [105]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor GATA-6 (GATA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [174]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [174]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [286]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [174]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [174]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Indomethacin DMSC4A7 Bursitis Approved [333]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Liver-expressed antimicrobial peptide 2 (LEAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Clozapine DMFC71L Schizophrenia 6A20 Approved [334]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [157]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arrestin domain-containing protein 3 (ARRDC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [2]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 4A1 (SLCO4A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [335]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase greatwall (MASTL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [48]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Arsenic DMTL2Y1 N. A. N. A. Approved [336]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sentrin-specific protease 5 (SENP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [17]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [319]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 16A (PPP1R16A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [105]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleosome assembly protein 1-like 5 (NAP1L5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [320]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable imidazolonepropionase (AMDHD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [88]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [32]
Milchsaure DM462BT Pruritus EC90 Investigative [291]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Perilipin-2 (PLIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [69]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [337]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [264]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division control protein 6 homolog (CDC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [338]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [339]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SMC5-SMC6 complex localization factor protein 1 (SLF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [93]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication complex GINS protein SLD5 (GINS4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [48]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [340]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein K (CENPK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [48]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spondin-2 (SPON2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [341]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [342]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-CoA acetyltransferase, cytosolic (ACAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [341]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Clozapine DMFC71L Schizophrenia 6A20 Approved [184]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein 24 (RBM24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [325]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [206]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [343]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [73]
Ethacrynic acid DM60QMR Edema MG29 Approved [197]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [127]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [69]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By THAP domain-containing protein 2 (THAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [344]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [34]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [314]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (SLC35B3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [78]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [31]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [22]
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Drug(s) Affected By ATP-binding cassette sub-family G member 5 (ABCG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [71]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [309]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [345]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [309]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein MIXL1 (MIXL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [346]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
Dolutegravir DMCZGRE Human immunodeficiency virus infection 1C62 Approved [347]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [70]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Regulator of cell cycle RGCC (RGCC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [348]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [112]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polyprenol reductase (SRD5A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [69]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [69]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [69]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinetochore protein Spc25 (SPC25)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase Sgk2 (SGK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [349]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [286]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [56]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromal cell-derived factor 2-like protein 1 (SDF2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [250]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sperm-associated antigen 4 protein (SPAG4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [350]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endothelial cell-specific molecule 1 (ESM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [351]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [98]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [245]
Arsenic DMTL2Y1 N. A. N. A. Approved [352]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [353]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [354]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein C12orf4 (FERRY3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [26]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [76]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [355]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [314]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Olfactomedin-like protein 3 (OLFML3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [54]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Paclitaxel DMLB81S Breast carcinoma Approved [356]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [325]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [206]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BMP-2-inducible protein kinase (BMP2K)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [38]
Indomethacin DMSC4A7 Bursitis Approved [333]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [245]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein DEPP1 (DEPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [81]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [82]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [166]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [81]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Fluoxetine DM3PD2C Bipolar depression Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [82]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [82]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleotide sugar transporter SLC35D1 (SLC35D1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 4 protein (DDIT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [288]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [123]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK2 (PLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [357]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Placenta-specific gene 8 protein (PLAC8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Arsenic DMTL2Y1 N. A. N. A. Approved [358]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [40]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Folliculin-interacting protein 2 (FNIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [359]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [96]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [42]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ]-phosphatase 2, mitochondrial (PDP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Ampicillin DMHWE7P Acute epiglottitis Approved [2]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Urethane DM7NSI0 N. A. N. A. Phase 4 [89]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 9 (DNAJB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [154]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [311]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [69]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxidative stress-induced growth inhibitor 1 (OSGIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Testosterone DM7HUNW Hot flushes GA30 Approved [15]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [15]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [69]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [69]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [69]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Procollagen C-endopeptidase enhancer 2 (PCOLCE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [360]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dermatan-sulfate epimerase (DSE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [76]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein inturned (INTU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [322]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [19]
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Drug(s) Affected By Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Selenium DM25CGV N. A. N. A. Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [12]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [57]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [348]
Testosterone enanthate DMB6871 N. A. N. A. Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [70]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Testosterone DM7HUNW Hot flushes GA30 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein SSUH2 homolog (SSUH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [287]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [322]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [34]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By DmX-like protein 1 (DMXL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [361]
Panobinostat DM58WKG Chronic graft versus host disease Approved [362]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [63]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [87]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [20]
Panobinostat DM58WKG Chronic graft versus host disease Approved [34]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [363]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [79]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [97]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [20]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [34]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [364]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [365]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [108]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [250]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible lipid droplet-associated protein (HILPDA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [52]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endothelial lipase (LIPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [35]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [107]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine sulfinic acid decarboxylase (CSAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [17]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [99]
Arsenic DMTL2Y1 N. A. N. A. Approved [30]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [26]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [366]
Milchsaure DM462BT Pruritus EC90 Investigative [291]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Proton-coupled zinc antiporter SLC30A1 (SLC30A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [361]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [66]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [13]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [14]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leukemia inhibitory factor (LIF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [171]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [243]
Leflunomide DMR8ONJ Arthritis FA20 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock 70 kDa protein 1A (HSPA1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [367]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Gefitinib DM15F0X Colon adenocarcinoma Approved [368]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Selenium DM25CGV N. A. N. A. Approved [76]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock cognate 71 kDa protein (HSPA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [370]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [371]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Quercetin DM3NC4M Obesity 5B81 Approved [372]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [126]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [259]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [373]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [375]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [376]
Methotrexate DM2TEOL Anterior urethra cancer Approved [377]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [378]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [379]
Quercetin DM3NC4M Obesity 5B81 Approved [380]
Fructose DM43AN2 Vomiting MD90 Approved [381]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [382]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [376]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [383]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [384]
Verapamil DMA7PEW Angina pectoris BA40 Approved [165]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [385]
Selenium DM25CGV N. A. N. A. Approved [76]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [386]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [387]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [388]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [389]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family B member 5 (ABCB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [390]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [249]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [32]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Katanin p60 ATPase-containing subunit A-like 1 (KATNAL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [2]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [18]
Bortezomib DMNO38U Leukemia Approved [229]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [92]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [201]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Methionine aminopeptidase 2 (METAP2) TTZL0OI MAP2_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) OTG2T749 CP24A_HUMAN Gene/Protein Processing [2]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) OTRT3F3U HMDH_HUMAN Gene/Protein Processing [2]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Gene/Protein Processing [2]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Gene/Protein Processing [2]
Acyl-CoA dehydrogenase family member 11 (ACAD11) OT3T9HAX ACD11_HUMAN Gene/Protein Processing [2]
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (SLC35B3) OTBDPI8I S35B3_HUMAN Gene/Protein Processing [2]
Adenylosuccinate synthetase isozyme 1 (ADSS1) OTF6FE38 PURA1_HUMAN Gene/Protein Processing [2]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [2]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [2]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [2]

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