Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM46FVD)

Drug Name
Ginsenoside Re Drug Info
Synonyms
Chikusetsusaponin IVc; Ginsenoside B2; Ginsenoside Re; PWAOOJDMFUQOKB-WCZZMFLVSA-N; Panaxoside RE; SCHEMBL669738; TR-036967; ZINC242620164; ginsenoside-Re; (20S)-ginsenoside Re; 2-O-(6-Deoxy-alpha-L-mannopyranosyl)-(3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-beta-D-glucopyranoside; 46F3R0BL3I; 51542-56-4; 52286-59-6; AKOS025310861; BDBM50378779; CHEBI:77148; CHEMBL510095; CS-3838; CTK8F0918; DB14815; EINECS 257-814-6; HY-N0044; MFCD00133369; NSC 308877; NSC-308877; UNII-46F3R0BL3I; s3811
Cross-matching ID
PubChem CID
441921
ChEBI ID
CHEBI:77148
CAS Number
CAS 52286-59-6
TTD Drug ID
DM46FVD
INTEDE Drug ID
DR2495

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Preclinical Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Alpha-L-rhamnosidase (lrA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
HY-N2258 DML4IAX N. A. N. A. Preclinical [1]
Rutin DMEHRAJ Discovery agent N.A. Investigative [1]
naringin DM4DG1Y Discovery agent N.A. Investigative [1]
PNA-l-rhamnopyranoside DMZF7RQ N. A. N. A. Investigative [1]
Drug(s) Metabolized By Beta-glucosidase (bglA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
SC-46553 DM6XNJR N. A. N. A. Phase 3 [2]
Ginsenoside Rb1 DMF70AB N. A. N. A. Investigative [2]
Ginsenoside Rg1 DMYE2SR N. A. N. A. Investigative [2]
Drug(s) Affected By Immunity-related GTPase family M protein (IRGM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [8]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [9]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [10]
Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [11]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [12]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [12]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [14]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [15]
Fluoxetine DM3PD2C Bipolar depression Approved [12]
Fructose DM43AN2 Vomiting MD90 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [17]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [12]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [18]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [19]
Verapamil DMA7PEW Angina pectoris BA40 Approved [20]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [21]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [20]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [22]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [25]
Quercetin DM3NC4M Obesity 5B81 Approved [26]
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Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [27]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [28]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [29]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [33]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [34]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [35]
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Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [36]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Selenium DM25CGV N. A. N. A. Approved [39]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [40]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [43]
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Drug(s) Affected By Trefoil factor 1 (TFF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Estrone DM5T6US Acne vulgaris ED80 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [45]
Testosterone DM7HUNW Hot flushes GA30 Approved [49]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [50]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [51]
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Drug(s) Affected By Progesterone receptor (PGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [52]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [54]
Estrone DM5T6US Acne vulgaris ED80 Approved [55]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [56]
Testosterone DM7HUNW Hot flushes GA30 Approved [57]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [51]
Goserelin DMAT8CG Breast cancer 2C60-2C65 Approved [58]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
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Drug(s) Affected By Potassium voltage-gated channel subfamily E member 1 (KCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [61]
Pentobarbital DMFNH7L Brain ischaemia 8B1Z Approved [62]
Verapamil DMA7PEW Angina pectoris BA40 Approved [63]
Propranolol DM79NTF Angina pectoris BA40 Approved [63]
Diltiazem DMAI7ZV Angina pectoris BA40 Approved [63]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [63]
Quinidine DMLPICK N. A. N. A. Approved [63]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [63]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [63]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [66]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Epinephrine DM3KJBC Acute asthma CA23 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Fructose DM43AN2 Vomiting MD90 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [72]
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Drug(s) Affected By Nitric oxide synthase 3 (NOS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [73]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [74]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [63]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Fructose DM43AN2 Vomiting MD90 Approved [80]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
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Drug(s) Affected By Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [14]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [82]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [83]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [85]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [86]
Leflunomide DMR8ONJ Arthritis FA20 Approved [87]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
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Drug(s) Affected By Glucose-6-phosphatase catalytic subunit 1 (G6PC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [14]
Fluoxetine DM3PD2C Bipolar depression Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [90]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [84]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [86]
Leflunomide DMR8ONJ Arthritis FA20 Approved [91]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [88]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [90]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [90]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [92]
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Drug(s) Affected By Sterol regulatory element-binding protein 1 (SREBF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [41]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [63]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [11]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [14]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [60]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [95]
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Drug(s) Affected By 5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [97]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [99]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [100]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [101]
Capsaicin DMGMF6V Back pain ME84.Z Approved [102]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [103]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [104]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [105]
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Drug(s) Affected By Nuclear receptor subfamily 0 group B member 2 (NR0B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [106]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [107]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [11]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [107]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [109]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [14]
Fluoxetine DM3PD2C Bipolar depression Approved [107]
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Drug(s) Affected By Serine/threonine-protein kinase STK11 (STK11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [111]
Selenium DM25CGV N. A. N. A. Approved [39]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [113]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [114]
Arsenic DMTL2Y1 N. A. N. A. Approved [115]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [116]
APR-246 DMNFADH Ovarian cancer 2C73 Phase 2 [117]
GDC-0980/RG7422 DMF3MV1 Non-hodgkin lymphoma 2B33.5 Phase 2 [118]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [119]
Folic Acid DMEMBJC Colorectal carcinoma Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [123]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [105]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [124]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [126]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [126]
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Drug(s) Affected By ATP-binding cassette sub-family C member 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [127]
Sulfinpyrazone DMEV954 Gout FA25 Approved [128]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [129]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [130]
Methotrexate DM2TEOL Anterior urethra cancer Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [132]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [124]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [133]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [134]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [135]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [136]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [136]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [92]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [135]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [136]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [137]
Gefitinib DM15F0X Colon adenocarcinoma Approved [135]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [138]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [135]
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Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [139]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [139]
Gefitinib DM15F0X Colon adenocarcinoma Approved [140]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [63]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [141]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [142]
Methotrexate DM2TEOL Anterior urethra cancer Approved [143]
Quercetin DM3NC4M Obesity 5B81 Approved [144]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [145]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [146]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Alpha-L-rhamnosidase (lrA) DEBI82Z A0A1V8Q7P3_9BIF Substrate [1]
Beta-glucosidase (bglA) DE9N4OU C6WCL5_ACTMD Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) OT7TNF0L AAPK1_HUMAN Post-Translational Modifications [3]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Regulation of Drug Effects [4]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Regulation of Drug Effects [4]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Regulation of Drug Effects [4]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Gene/Protein Processing [5]
Glucose-6-phosphatase catalytic subunit 1 (G6PC1) OTJ6FM9F G6PC1_HUMAN Gene/Protein Processing [3]
Immunity-related GTPase family M protein (IRGM) OTKD3O5Z IRGM_HUMAN Gene/Protein Processing [6]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Gene/Protein Processing [6]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Regulation of Drug Effects [4]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Post-Translational Modifications [5]

References

1 Metabolism of rutin and poncirin by human intestinal microbiota and cloning of their metabolizing alpha-L-rhamnosidase from Bifidobacterium dentium. J Microbiol Biotechnol. 2015 Jan;25(1):18-25.
2 Characterization of the ginsenoside-transforming recombinant beta-glucosidase from Actinosynnema mirum and bioconversion of major ginsenosides into minor ginsenosides. Appl Microbiol Biotechnol. 2013 Jan;97(2):649-59.
3 Ginsenoside Re lowers blood glucose and lipid levels via activation of AMP-activated protein kinase in HepG2 cells and high-fat diet fed mice. Int J Mol Med. 2012 Jan;29(1):73-80. doi: 10.3892/ijmm.2011.805. Epub 2011 Oct 3.
4 Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb-drug interactions on OATP1B3. Br J Pharmacol. 2015 Feb;172(4):1059-73. doi: 10.1111/bph.12971. Epub 2015 Jan 20.
5 Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor. FEBS Lett. 2007 May 29;581(13):2423-8. doi: 10.1016/j.febslet.2007.04.055. Epub 2007 Apr 30.
6 Ginsenoside Re enhances survival of human CD4+ T cells through regulation of autophagy. Int Immunopharmacol. 2010 May;10(5):626-31. doi: 10.1016/j.intimp.2010.03.002. Epub 2010 Mar 15.
7 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
8 Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study. Oncotarget. 2017 Jan 3;8(1):1369-1391. doi: 10.18632/oncotarget.13622.
9 Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling pathways. Environ Int. 2020 Feb;135:105414. doi: 10.1016/j.envint.2019.105414. Epub 2019 Dec 23.
10 A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling. PLoS One. 2017 May 25;12(5):e0178302. doi: 10.1371/journal.pone.0178302. eCollection 2017.
11 Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. Food Chem Toxicol. 2021 Dec;158:112664. doi: 10.1016/j.fct.2021.112664. Epub 2021 Nov 9.
12 Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett. 2006 Mar 13;395(3):185-90. doi: 10.1016/j.neulet.2005.10.096. Epub 2005 Dec 1.
13 The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007 Jun;97(2):582-94.
14 Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
15 Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. Pain. 2007 Mar;128(1-2):136-47.
16 Effects of four-week high-fructose diet on gene expression in skeletal muscle of healthy men. Diabetes Metab. 2008 Feb;34(1):82-5. doi: 10.1016/j.diabet.2007.08.004. Epub 2007 Dec 11.
17 Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis. Biochem Pharmacol. 2004 Dec 1;68(11):2177-86.
18 Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide. Med Oncol. 2011 Dec;28(4):1225-54.
19 Cannabidiol Activates Neuronal Precursor Genes in Human Gingival Mesenchymal Stromal Cells. J Cell Biochem. 2017 Jun;118(6):1531-1546. doi: 10.1002/jcb.25815. Epub 2016 Dec 29.
20 Selection of drugs to test the specificity of the Tg.AC assay by screening for induction of the gadd153 promoter in vitro. Toxicol Sci. 2003 Aug;74(2):260-70. doi: 10.1093/toxsci/kfg113. Epub 2003 May 2.
21 Sertraline induces endoplasmic reticulum stress in hepatic cells. Toxicology. 2014 Aug 1;322:78-88. doi: 10.1016/j.tox.2014.05.007. Epub 2014 May 24.
22 Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation. J Mol Endocrinol. 2004 Apr;32(2):397-414.
23 Microarray analysis of H2O2-, HNE-, or tBH-treated ARPE-19 cells. Free Radic Biol Med. 2002 Nov 15;33(10):1419-32.
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