Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBUI2A)

Drug Name
BETULINIC ACID Drug Info
Synonyms
betulinic acid; 472-15-1; Mairin; Betulic acid; NSC 113090; CCRIS 6748; 3-Hydroxylup-20(29)-en-28-oic acid; UNII-4G6A18707N; 3beta-Hydroxy-20(29)-lupaene-28-oic acid; EINECS 207-448-8; NSC677578; als-357; NSC 677578; CHEMBL269277; CHEBI:3087; 3beta-Hydroxy-lup-20(29)-en-28-oic acid; 4G6A18707N; Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-; AK-72848; Lupatic Acid; SMR000445624
Indication
Disease Entry ICD 11 Status REF
Melanoma 2C30 Phase 1 [1]
Cross-matching ID
PubChem CID
64971
ChEBI ID
CHEBI:3087
CAS Number
CAS 472-15-1
TTD Drug ID
DMBUI2A

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Herpes simplex virus DNA polymerase UL30 (HSV UL30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [10]
Aciclovir DMYLOVR Genital herpes 1A94 Approved [11]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [12]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [13]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [11]
Valganciclovir DMS2IUH Virus infection 1A24-1D9Z Approved [14]
Penciclovir DMOUMDV Herpes simplex labialis 1F00.01 Approved [15]
Famciclovir DMJHLSD Meniere disease AB31.0 Approved [16]
Valacyclovir Hydrochloride DM5I1CE Herpes simplex virus infection 1F00 Approved [11]
Foscavir DM9KJLZ Cytomegalovirus retinitis 9B72.00 Approved [14]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [17]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [18]
Gefitinib DM15F0X Colon adenocarcinoma Approved [3]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [21]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Gefitinib DM15F0X Colon adenocarcinoma Approved [27]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [28]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [29]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [30]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [31]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [30]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [32]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [34]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [35]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [36]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [37]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [38]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [40]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [41]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [42]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [43]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [49]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [50]
Testosterone DM7HUNW Hot flushes GA30 Approved [51]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [52]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [53]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [58]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [60]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [61]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [62]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [63]
Gefitinib DM15F0X Colon adenocarcinoma Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [29]
Etretinate DM2CZFA Keratosis ED56 Approved [66]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [68]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [70]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [71]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [72]
Gefitinib DM15F0X Colon adenocarcinoma Approved [73]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [74]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [75]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [76]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [77]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [78]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [80]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [81]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [85]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [86]
Paclitaxel DMLB81S Breast carcinoma Approved [87]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [88]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [89]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [90]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [91]
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Drug(s) Affected By DNA topoisomerase 1 (TOP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [39]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Selenium DM25CGV N. A. N. A. Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [95]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [96]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [97]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [100]
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Drug(s) Affected By DNA topoisomerase 2-alpha (TOP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [101]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [103]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [105]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [97]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [107]
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Drug(s) Affected By Proliferating cell nuclear antigen (PCNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [109]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [110]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [111]
Meloxicam DM2AR7L Arthritis FA20 Approved [112]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [113]
Epinephrine DM3KJBC Acute asthma CA23 Approved [114]
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Drug(s) Affected By Parathyroid hormone-related protein (PTHLH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [95]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [115]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [117]
Testosterone DM7HUNW Hot flushes GA30 Approved [118]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [122]
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Drug(s) Affected By Phospholipase A2, membrane associated (PLA2G2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Panobinostat DM58WKG Chronic graft versus host disease Approved [126]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [127]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [128]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [129]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [130]
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Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [131]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [132]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Selenium DM25CGV N. A. N. A. Approved [109]
Etretinate DM2CZFA Keratosis ED56 Approved [66]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [31]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [133]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [67]
Methotrexate DM2TEOL Anterior urethra cancer Approved [105]
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Drug(s) Affected By CCAAT/enhancer-binding protein beta (CEBPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [93]
Methotrexate DM2TEOL Anterior urethra cancer Approved [95]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [134]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [97]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [137]
Panobinostat DM58WKG Chronic graft versus host disease Approved [126]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [138]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [139]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [43]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [140]
Gefitinib DM15F0X Colon adenocarcinoma Approved [73]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Selenium DM25CGV N. A. N. A. Approved [94]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [142]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [143]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [144]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [145]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [146]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [42]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [149]
Gefitinib DM15F0X Colon adenocarcinoma Approved [150]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [153]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [145]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [154]
Paclitaxel DMLB81S Breast carcinoma Approved [155]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [156]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [144]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [39]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [157]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [42]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [147]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [158]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [159]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [89]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [43]
Gefitinib DM15F0X Colon adenocarcinoma Approved [160]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [162]
Selenium DM25CGV N. A. N. A. Approved [94]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [110]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [142]
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Drug(s) Affected By Polycomb complex protein BMI-1 (BMI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [164]
Ibrutinib DMHZCPO Mantle cell lymphoma 2A85.5 Approved [165]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [166]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [167]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [169]
Arsenic DMTL2Y1 N. A. N. A. Approved [170]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [171]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [172]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [173]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [103]
Gefitinib DM15F0X Colon adenocarcinoma Approved [64]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [175]
Etretinate DM2CZFA Keratosis ED56 Approved [66]
Prednisone DM2HG4X Acute asthma CA23 Approved [176]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [31]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [177]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [178]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [179]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [180]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [86]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [181]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [182]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [183]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [184]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [185]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [186]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [187]
Gefitinib DM15F0X Colon adenocarcinoma Approved [3]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [188]
Selenium DM25CGV N. A. N. A. Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [189]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [190]
Quercetin DM3NC4M Obesity 5B81 Approved [191]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [192]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [194]
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Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [195]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [78]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [196]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [197]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [198]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [198]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [134]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [199]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [96]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [200]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [201]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [41]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [202]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [203]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [29]
Meloxicam DM2AR7L Arthritis FA20 Approved [204]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [205]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [206]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [208]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [209]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [157]
Gefitinib DM15F0X Colon adenocarcinoma Approved [210]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [211]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [29]
Selenium DM25CGV N. A. N. A. Approved [94]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [205]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
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Drug(s) Affected By Bcl-2 homologous antagonist/killer (BAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [212]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [213]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [214]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [215]
Levamisole DM5EN79 Parasitic infection 1D0Y-1G2Z Approved [216]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [217]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [218]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [220]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Prednisone DM2HG4X Acute asthma CA23 Approved [222]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [222]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [223]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [224]
Epinephrine DM3KJBC Acute asthma CA23 Approved [114]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
Fluoxetine DM3PD2C Bipolar depression Approved [225]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carbonic anhydrase 9 (CA9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetazolamide DM1AF5U Absence epilepsy Approved [227]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [223]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [228]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [229]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [127]
Ampicillin DMHWE7P Acute epiglottitis Approved [56]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [167]
Bortezomib DMNO38U Leukemia Approved [231]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [169]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30) TTIU7X1 DPOL_HHV11 Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [3]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [4]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Gene/Protein Processing [5]
Carbonic anhydrase 9 (CA9) OTNA51XT CAH9_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [7]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [6]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [3]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Gene/Protein Processing [9]

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