Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMQUSBT)

Drug Name
Daunorubicin Drug Info
Synonyms
daunorubicin; Daunomycin; 20830-81-3; Rubidomycin; Cerubidine; Daunorubicine; Acetyladriamycin; Leukaemomycin C; Daunorubicinum; Daunarubicinum; Daunorrubicina; Daunamycin; Cerubidin; DaunoXome; Rubomycin C; (+)-Daunomycin; Daunoblastin; Anthracyline; Rubomycin; Daunorubicinum [INN-Latin]; RP 13057; Daunorubicin [INN:BAN]; RCRA waste no U059; FI6339; NSC-82151; DAUNORUBICIN HCL; DaunoXome (TN); UNII-ZS7284E0ZP; CCRIS 914; ZS7284E0ZP; CHEBI:41977; HSDB 5095; C27H29NO10; NCI-C04693; EINECS 244-069-7; Ondena; NSC 83142; Acetyladriamycin; Daunoblastine; Antibiotics from Streptomyces coeruleorubidus; DM1; FI 6339; Dauno-Rubidomycine; Daunorubicin (INN); Daunorubicin (liposomal); Daunorubicin, Hydrochloride; VS-103; (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside; (7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Anthracycline
Indication
Disease Entry ICD 11 Status REF
Acute monocytic leukemia Approved [1]
Acute myelogenous leukaemia 2A41 Approved [1]
Acute myeloid leukaemia 2A60 Approved [2]
Kaposi sarcoma 2B57 Approved [3]
Leukemia Approved [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [4]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
30323
ChEBI ID
CHEBI:41977
CAS Number
CAS 20830-81-3
TTD Drug ID
DMQUSBT
VARIDT Drug ID
DR00284
INTEDE Drug ID
DR0424

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Patented Agent(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting DNA replication (DNA repli)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Chlorambucil DMRKE63 Chronic lymphocytic leukaemia 2A82.0 Approved [23]
Ozenoxacin DM6KZMG Impetigo 1B72 Approved [24]
Elliptinium acetate DMZC6GT Solid tumour/cancer 2A00-2F9Z Approved [25]
DFP-10917 DM1WNGJ Acute myeloid leukaemia 2A60 Phase 3 [26]
Drug(s) Targeting Human Deoxyribonucleic acid (hDNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [27]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [28]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [29]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [30]
Carboplatin DMG281S Adenocarcinoma 2D40 Approved [31]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [32]
Procarbazine DMIK367 Hodgkin lymphoma 2B30 Approved [33]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [34]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [35]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [36]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
Methotrexate DM2TEOL Anterior urethra cancer Approved [38]
Folic Acid DMEMBJC Colorectal carcinoma Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [40]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [41]
Verapamil DMA7PEW Angina pectoris BA40 Approved [42]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [43]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [44]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [45]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [42]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [130]
Folic Acid DMEMBJC Colorectal carcinoma Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [133]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [134]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [135]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [136]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [137]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [137]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [42]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [10]
Folic Acid DMEMBJC Colorectal carcinoma Approved [47]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [10]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [48]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [10]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [50]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Folic Acid DMEMBJC Colorectal carcinoma Approved [53]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [54]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [55]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [56]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [57]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [56]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [58]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [59]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Transported By Multidrug resistance-associated protein 6 (ABCC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [7]
Benzbromarone DMC3YUA Gout FA25 Approved [60]
Epipodophyllotoxins DMVNR20 N. A. N. A. Preclinical [7]
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [61]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [62]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [63]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [64]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [65]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [66]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [67]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [68]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [62]
Verapamil DMA7PEW Angina pectoris BA40 Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [70]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [71]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [72]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [74]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [75]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [67]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [76]
Verapamil DMA7PEW Angina pectoris BA40 Approved [77]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [79]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [80]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [82]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [76]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [83]
Estrone DM5T6US Acne vulgaris ED80 Approved [84]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [85]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [86]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By NADPH-dependent carbonyl reductase 1 (CBR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [88]
FENOFIBRIC ACID DMGO2MC Cardiovascular disease BA00-BE2Z Approved [89]
PGF2alpha DM4XAU7 Solid tumour/cancer 2A00-2F9Z Clinical trial [90]
VUFB-11502 DM7WFR0 N. A. N. A. Preclinical [91]
Phenanthrene-9,10-dione DMG8KS9 Discovery agent N.A. Investigative [92]
BRN-3548355 DM4KXT0 N. A. N. A. Investigative [93]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Metabolized By NADPH-dependent carbonyl reductase 3 (CBR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
Trastuzumab emtansine DMU1LXS HER2-positive breast cancer 2C60-2C65 Phase 2 [95]
Phenanthrene-9,10-dione DMG8KS9 Discovery agent N.A. Investigative [92]
1H-Indole-2,3-dione DMOZ91H Discovery agent N.A. Investigative [96]
Nitrobenzaldehyde DM4UHB5 N. A. N. A. Investigative [94]
ACMC-209cv7 DMQCSFB N. A. N. A. Investigative [94]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Metabolized By NADPH-cytochrome P450 reductase (CPR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [97]
Nitrofurantoin DM7PQIK Urinary tract infection GC08 Approved [98]
Tacrolimus DMZ7XNQ Graft-versus-host disease 4B24 Approved [99]
Benzphetamine DMIJATC Obesity 5B81 Approved [100]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [101]
Menadiol sodium diphosphate DMP9N85 Coagulation defect 3B10.0 Approved [102]
Amrubicin DM6SGUB Small-cell lung cancer 2C25.Y Phase 3 [103]
Nitrobenzodiazepine DM254EW N. A. N. A. Investigative [104]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Carbonyl reductase 3 (CBR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Bortezomib DMNO38U Leukemia Approved [109]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [14]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [95]
Acetohexamide DMR6N7H Diabetic complication 5A2Y Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [113]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [113]
Gefitinib DM15F0X Colon adenocarcinoma Approved [114]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [112]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [115]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [116]
Methotrexate DM2TEOL Anterior urethra cancer Approved [117]
Quercetin DM3NC4M Obesity 5B81 Approved [118]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [119]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [121]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [122]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [123]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [124]
Cepharanthine DM9Y5JB N. A. N. A. Approved [125]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [126]
Clozapine DMFC71L Schizophrenia 6A20 Approved [127]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [128]
Trifluoperazine DMKBYWI Anxiety Approved [129]
Olanzapine DMPFN6Y Bipolar depression Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Benzatropine DMF7EXL Parkinsonian disorder Approved [144]
Clozapine DMFC71L Schizophrenia 6A20 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amlexanox DM0DQM5 Respiratory tract inflammation CA07 Approved [145]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [146]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [146]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [150]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [154]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [155]
Estrone DM5T6US Acne vulgaris ED80 Approved [156]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [157]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [158]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [159]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [160]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SEC14-like protein 3 (SEC14L3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [162]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
Drug(s) Affected By Retinoic acid receptor gamma (RARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [165]
Ethanol DMDRQZU Chronic pain MG30 Approved [166]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [167]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [169]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [170]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [171]
Fenretinide DMRD5SP Macular degeneration 9B78.3 Phase 3 [172]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [173]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [174]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [177]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [178]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [179]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [180]
Quercetin DM3NC4M Obesity 5B81 Approved [181]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [182]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Voltage-dependent T-type calcium channel subunit alpha-1G (CACNA1G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [183]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [186]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
Mibefradil DMU9VDS Glioblastoma multiforme 2A00.0 Phase 1 [187]
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Drug(s) Affected By Tyrosine-protein kinase JAK2 (JAK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Momelotinib DMF98Q0 Myelofibrosis 2A20.2 Approved [188]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [189]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [191]
Estrone DM5T6US Acne vulgaris ED80 Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [193]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium channel subunit beta-2 (SCN2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [195]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [186]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [198]
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Drug(s) Affected By LIM domain-binding protein 3 (LDB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [202]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [204]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [205]
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Drug(s) Affected By Creatine kinase M-type (CKM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [206]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Salbutamol DMN9CWF Acute asthma CA23 Approved [208]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Carbimazole DMULAI4 Hyperthyroidism 5A02 Approved [211]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
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Drug(s) Affected By Glutathione peroxidase 1 (GPX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Amlexanox DM0DQM5 Respiratory tract inflammation CA07 Approved [213]
Selenium DM25CGV N. A. N. A. Approved [214]
Methotrexate DM2TEOL Anterior urethra cancer Approved [215]
Quercetin DM3NC4M Obesity 5B81 Approved [216]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [217]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [218]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [219]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycogen phosphorylase, muscle form (PYGM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prednisone DM2HG4X Acute asthma CA23 Approved [221]
Haloperidol DM96SE0 Delirium Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [222]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dystrophin (DMD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [224]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Thioguanine DM7NKEV Acute lymphocytic leukaemia 2B33.3 Approved [226]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Gentamicin DMKINJO Bacteremia 1A73 Approved [227]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin-7 (MYH7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Folic Acid DMEMBJC Colorectal carcinoma Approved [228]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [228]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [229]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin-6 (MYH6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [230]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [231]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Folic Acid DMEMBJC Colorectal carcinoma Approved [232]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [228]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [154]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Troponin T, slow skeletal muscle (TNNT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [237]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [238]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Receptor tyrosine-protein kinase erbB-3 (ERBB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [239]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [240]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [242]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [243]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sarcoplasmic reticulum histidine-rich calcium-binding protein (HRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [144]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Folic Acid DMEMBJC Colorectal carcinoma Approved [232]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [245]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [245]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [246]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [248]
Methotrexate DM2TEOL Anterior urethra cancer Approved [249]
Epinephrine DM3KJBC Acute asthma CA23 Approved [250]
Quercetin DM3NC4M Obesity 5B81 Approved [251]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [252]
Fructose DM43AN2 Vomiting MD90 Approved [253]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [247]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/potassium-transporting ATPase subunit alpha-2 (ATP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [255]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Angina pectoris BA40 Approved [256]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [256]
Quinidine DMLPICK N. A. N. A. Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [257]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mepivacaine DMH2NMY Analgesia MB40.8 Approved [257]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Ropivacaine DMSPJG2 Anaesthesia 9A78.6 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By cAMP-dependent protein kinase catalytic subunit PRKX (PRKX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [258]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [169]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myomesin-2 (MYOM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [260]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [261]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [262]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inward rectifier potassium channel 2 (KCNJ2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [237]
Arsenic DMTL2Y1 N. A. N. A. Approved [263]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin, alpha skeletal muscle (ACTA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Folic Acid DMEMBJC Colorectal carcinoma Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iroquois-class homeodomain protein IRX-4 (IRX4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [247]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [265]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [266]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [267]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin-2 (ANK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [247]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [269]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [270]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Verapamil DMA7PEW Angina pectoris BA40 Approved [272]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [247]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [273]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Meloxicam DM2AR7L Arthritis FA20 Approved [276]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [277]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [278]
Quinidine DMLPICK N. A. N. A. Approved [279]
Verapamil DMA7PEW Angina pectoris BA40 Approved [280]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [281]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [281]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [282]
Propranolol DM79NTF Angina pectoris BA40 Approved [283]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [284]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [285]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 4 (DUSP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [286]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium channel protein type 5 subunit alpha (SCN5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [112]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [287]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [288]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [289]
Meloxicam DM2AR7L Arthritis FA20 Approved [290]
Quercetin DM3NC4M Obesity 5B81 Approved [291]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [292]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Retigabine DMGNYIH Behcet disease 4A62 Approved [294]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 3A (PPP1R3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone enanthate DMB6871 N. A. N. A. Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
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Drug(s) Affected By Caveolae-associated protein 4 (CAVIN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [174]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [296]
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Drug(s) Affected By Nebulin-related-anchoring protein (NRAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [222]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
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Drug(s) Affected By Ryanodine receptor 2 (RYR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [297]
Isoproterenol DMK7MEY Atrioventricular block Approved [298]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Atenolol DMNKG1Z Angina pectoris BA40 Approved [297]
Metoprolol DMOJ0V6 Acute coronary syndrome BA41 Approved [297]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [299]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [301]
Quercetin DM3NC4M Obesity 5B81 Approved [302]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [303]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [304]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [304]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [305]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [306]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone-lysine N-methyltransferase PRDM16 (PRDM16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [307]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Folic Acid DMEMBJC Colorectal carcinoma Approved [232]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [308]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Arsenic DMTL2Y1 N. A. N. A. Approved [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [310]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [311]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [202]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [246]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Atrial natriuretic peptide-converting enzyme (CORIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [312]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [15]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [314]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [15]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [315]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [316]
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Drug(s) Affected By DNA fragmentation factor subunit alpha (DFFA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Capsaicin DMGMF6V Back pain ME84.Z Approved [318]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [109]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
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Drug(s) Affected By Agrin (AGRN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [173]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [173]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [319]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [320]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [321]
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Drug(s) Affected By Etoposide-induced protein 2.4 homolog (EI24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Amifostine DM5FL14 Mucositis CA00 Approved [322]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
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Drug(s) Affected By Tax1-binding protein 3 (TAX1BP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [323]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [155]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
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Drug(s) Affected By Aurora kinase A (AURKA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [324]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [301]
Methotrexate DM2TEOL Anterior urethra cancer Approved [325]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [326]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [327]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [301]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
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Drug(s) Affected By Protein Mdm4 (MDM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [109]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [328]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [329]
Gefitinib DM15F0X Colon adenocarcinoma Approved [330]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [331]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [248]
Etretinate DM2CZFA Keratosis ED56 Approved [332]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [301]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [333]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [334]
Quercetin DM3NC4M Obesity 5B81 Approved [335]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [336]
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Drug(s) Affected By Cytoplasmic protein NCK2 (NCK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [16]
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Drug(s) Affected By Protein regulator of cytokinesis 1 (PRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [239]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [337]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [173]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTPase NRas (NRAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [338]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [339]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [340]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [341]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [342]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [343]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [344]
Gefitinib DM15F0X Colon adenocarcinoma Approved [345]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [346]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [347]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [348]
Quercetin DM3NC4M Obesity 5B81 Approved [349]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [350]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [346]
Estrone DM5T6US Acne vulgaris ED80 Approved [351]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [352]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [239]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [139]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [353]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [337]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [355]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [356]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [357]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [358]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [359]
Paclitaxel DMLB81S Breast carcinoma Approved [360]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [361]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [362]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [363]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [365]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [366]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [367]
Methotrexate DM2TEOL Anterior urethra cancer Approved [368]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [369]
Quercetin DM3NC4M Obesity 5B81 Approved [370]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [372]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [373]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
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Drug(s) Affected By Endothelin-1 (EDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [374]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [375]
Methotrexate DM2TEOL Anterior urethra cancer Approved [376]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [377]
Quercetin DM3NC4M Obesity 5B81 Approved [378]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [380]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [381]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [382]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [383]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [384]
Gefitinib DM15F0X Colon adenocarcinoma Approved [385]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [386]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [387]
Methotrexate DM2TEOL Anterior urethra cancer Approved [388]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [389]
Quercetin DM3NC4M Obesity 5B81 Approved [390]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A2 (ANXA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Quercetin DM3NC4M Obesity 5B81 Approved [391]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [392]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [393]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [394]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [395]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [396]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Sp1 (SP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [397]
Quercetin DM3NC4M Obesity 5B81 Approved [398]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [399]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [400]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [401]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [397]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [402]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [403]
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Drug(s) Affected By Interleukin-6 receptor subunit alpha (IL6R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [404]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [405]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Testosterone enanthate DMB6871 N. A. N. A. Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [198]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [406]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [407]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [408]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A4 (ANXA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [409]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [410]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [411]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Gefitinib DM15F0X Colon adenocarcinoma Approved [412]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [413]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [248]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [414]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [277]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [414]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [415]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [416]
Methotrexate DM2TEOL Anterior urethra cancer Approved [417]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [418]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [419]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [420]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [160]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [421]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [422]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [423]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [424]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [423]
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Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [425]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [425]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [425]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [426]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [427]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [428]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [429]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [21]
Selenium DM25CGV N. A. N. A. Approved [430]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [431]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [269]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [432]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [433]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [434]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [112]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Verapamil DMA7PEW Angina pectoris BA40 Approved [272]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [435]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [436]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [437]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein tau (MAPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [438]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [439]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [440]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [441]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [442]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Testosterone enanthate DMB6871 N. A. N. A. Approved [295]
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Drug(s) Affected By C-C motif chemokine 4 (CCL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [217]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [443]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [444]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [445]
Betamethasone DMAHJEF Acute adrenal insufficiency Approved [406]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [406]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [446]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [239]
Gefitinib DM15F0X Colon adenocarcinoma Approved [447]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [448]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [449]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [450]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [451]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [452]
Quercetin DM3NC4M Obesity 5B81 Approved [453]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [182]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [454]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [182]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
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Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [455]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [456]
Methotrexate DM2TEOL Anterior urethra cancer Approved [457]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [458]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [459]
Quercetin DM3NC4M Obesity 5B81 Approved [460]
Fructose DM43AN2 Vomiting MD90 Approved [253]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [461]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [456]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [462]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [463]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [464]
Selenium DM25CGV N. A. N. A. Approved [139]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [230]
Etretinate DM2CZFA Keratosis ED56 Approved [465]
Methotrexate DM2TEOL Anterior urethra cancer Approved [466]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [467]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [468]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [469]
Quercetin DM3NC4M Obesity 5B81 Approved [470]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-responsive element-binding protein 1 (CREB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [471]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [472]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [473]
Selenium DM25CGV N. A. N. A. Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [474]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [399]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [475]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [475]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [476]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [477]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Natriuretic peptides B (NPPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [478]
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [480]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [381]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [481]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [482]
Ethanol DMDRQZU Chronic pain MG30 Approved [483]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sphingomyelin phosphodiesterase (SMPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [251]
Fluoxetine DM3PD2C Bipolar depression Approved [484]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [485]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syndecan-1 (SDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [486]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [487]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [488]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [153]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribosomal protein S6 kinase beta-1 (RPS6KB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [489]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [490]
Gefitinib DM15F0X Colon adenocarcinoma Approved [491]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [492]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [386]
Quercetin DM3NC4M Obesity 5B81 Approved [493]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [494]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [495]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [496]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-E1 (CCNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [497]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [498]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [277]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [387]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Fluoxetine DM3PD2C Bipolar depression Approved [499]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [500]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [501]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [502]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [503]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [504]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [472]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [436]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [505]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [506]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [507]
Gefitinib DM15F0X Colon adenocarcinoma Approved [508]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [509]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [510]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [511]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [504]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [512]
Paclitaxel DMLB81S Breast carcinoma Approved [513]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [514]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [503]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [112]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [515]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [436]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [505]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D3 (CCND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [516]
Gefitinib DM15F0X Colon adenocarcinoma Approved [517]
Quercetin DM3NC4M Obesity 5B81 Approved [390]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [518]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [519]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [520]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [521]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [306]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By M-phase inducer phosphatase 1 (CDC25A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [516]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
Methotrexate DM2TEOL Anterior urethra cancer Approved [388]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [522]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [337]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [523]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [524]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [525]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [526]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [527]
Quercetin DM3NC4M Obesity 5B81 Approved [528]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [529]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [530]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [531]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [252]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [532]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [533]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [534]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [535]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [536]
Gefitinib DM15F0X Colon adenocarcinoma Approved [330]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Etretinate DM2CZFA Keratosis ED56 Approved [332]
Prednisone DM2HG4X Acute asthma CA23 Approved [537]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [277]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [300]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [538]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [538]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [539]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [540]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [490]
Gefitinib DM15F0X Colon adenocarcinoma Approved [491]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [541]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [542]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [543]
Quercetin DM3NC4M Obesity 5B81 Approved [544]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [545]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [485]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [546]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [547]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [359]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [548]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [549]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [550]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [551]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [552]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [270]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [516]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [224]
Prednisone DM2HG4X Acute asthma CA23 Approved [537]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [522]
Quercetin DM3NC4M Obesity 5B81 Approved [553]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [554]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [357]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [555]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [556]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [557]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 inhibitor B (CDKN2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [516]
Gefitinib DM15F0X Colon adenocarcinoma Approved [558]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Prednisone DM2HG4X Acute asthma CA23 Approved [537]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [559]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [560]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [561]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein kinase CLK2 (CLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [231]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [562]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [246]
T83193 DMHO29Y Discovery agent N.A. Patented [563]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [564]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [565]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [566]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [567]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [271]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [435]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [273]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [568]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [248]
Meloxicam DM2AR7L Arthritis FA20 Approved [569]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [570]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [571]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [440]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [572]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [476]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [573]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [574]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [575]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [576]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [577]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [515]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [578]
Gefitinib DM15F0X Colon adenocarcinoma Approved [412]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [273]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [579]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [580]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [581]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [582]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Sp3 (SP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [397]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [397]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [403]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [583]
Promegestone DMK4S8I Gynecological disease GA6Z Approved [584]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [585]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [586]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Vitamin C DMXJ7O8 Adenocarcinoma 2D40 Approved [587]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor delta (PPARD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [175]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [588]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [589]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [591]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [592]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [593]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Antigen peptide transporter 1 (TAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [139]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [538]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [379]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [538]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [486]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCAAT/enhancer-binding protein zeta (CEBPZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [594]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [170]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [16]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [241]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein kinase C delta type (PRKCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [146]
Butorphanol DM5KYPJ Pain MG30-MG3Z Approved [595]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [596]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [597]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [598]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [599]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [436]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [247]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [600]
Methotrexate DM2TEOL Anterior urethra cancer Approved [601]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [602]
Quercetin DM3NC4M Obesity 5B81 Approved [251]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [443]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [247]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [603]
Ethacrynic acid DM60QMR Edema MG29 Approved [604]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [605]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [606]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [607]
Etretinate DM2CZFA Keratosis ED56 Approved [332]
Quercetin DM3NC4M Obesity 5B81 Approved [251]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [608]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [146]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [231]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [609]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [610]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [542]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [522]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [611]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [612]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Testosterone DM7HUNW Hot flushes GA30 Approved [613]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [573]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [183]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoblastoma-binding protein 5 (RBBP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone enanthate DMB6871 N. A. N. A. Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Ethanol DMDRQZU Chronic pain MG30 Approved [614]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [615]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [616]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor E2F5 (E2F5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Paclitaxel DMLB81S Breast carcinoma Approved [617]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [408]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Fluoxetine DM3PD2C Bipolar depression Approved [254]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Estrone DM5T6US Acne vulgaris ED80 Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [266]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [173]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Quinone oxidoreductase PIG3 (TP53I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [248]
Methotrexate DM2TEOL Anterior urethra cancer Approved [376]
Quercetin DM3NC4M Obesity 5B81 Approved [618]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [619]
Amifostine DM5FL14 Mucositis CA00 Approved [322]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [620]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [173]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By EPM2A-interacting protein 1 (EPM2AIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [621]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RBBP6 (RBBP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [535]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [622]
Menthol DMG2KW7 Back pain ME84.Z Approved [184]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bile acid receptor (NR1H4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [623]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [21]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [624]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [625]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [373]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [21]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [624]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [626]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [627]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [628]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [629]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [561]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [630]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BRCA1-associated RING domain protein 1 (BARD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [631]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [632]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [408]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK3 (PLK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [173]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [633]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADPH oxidase 4 (NOX4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [634]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [635]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [636]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Capsaicin DMGMF6V Back pain ME84.Z Approved [637]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [638]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [639]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [320]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [640]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sphingomyelin phosphodiesterase 3 (SMPD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [641]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [642]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [169]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [642]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box/WD repeat-containing protein 1A (BTRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [202]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [643]
Calphostin C DM9X2D0 N. A. N. A. Terminated [644]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [223]
Milchsaure DM462BT Pruritus EC90 Investigative [645]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [646]
Mepacrine DMU8L7C Discovery agent N.A. Investigative [647]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-binding protein 39 (CAB39)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [266]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [16]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Camptothecin DM6CHNJ Solid tumour/cancer 2A00-2F9Z Phase 3 [16]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [204]
Geldanamycin DMS7TC5 Kidney cancer 2C90.0 Discontinued in Phase 2 [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [648]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase ABL1 (ABL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [112]
Anagrelide DMSQ8MD Thrombocythemia 3B63 Approved [112]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [649]
Quercetin DM3NC4M Obesity 5B81 Approved [291]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [650]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Capsaicin DMGMF6V Back pain ME84.Z Approved [651]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [218]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [246]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [296]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF1A (KIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [538]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [337]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [538]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [241]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [652]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [541]
Quercetin DM3NC4M Obesity 5B81 Approved [653]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [454]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [373]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [654]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [524]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [573]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 28 member 3 (SLC28A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [486]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [655]
ANW-32821 DMMJOZD N. A. N. A. Phase 2 [656]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [316]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [657]
Milchsaure DM462BT Pruritus EC90 Investigative [645]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [658]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein GAPT (GAPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [328]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [202]
Fenfluramine DM0762O Dravet syndrome 8A61.11 Phase 3 [659]
Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [660]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [661]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [362]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [437]
Gefitinib DM15F0X Colon adenocarcinoma Approved [662]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [492]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [663]
Selenium DM25CGV N. A. N. A. Approved [139]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [664]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [542]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glypican-5 (GPC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Folic Acid DMEMBJC Colorectal carcinoma Approved [232]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [665]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [223]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [658]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Voltage-dependent L-type calcium channel subunit alpha-1S (CACNA1S)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
Drug(s) Affected By Ephexin-1 (NGEF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [666]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spliceosome-associated protein CWC27 homolog (CWC27)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [488]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [667]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [668]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [657]
Milchsaure DM462BT Pruritus EC90 Investigative [645]
[3H]methyltrienolone DMTSGOW Discovery agent N.A. Investigative [669]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-13 (CDH13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Folic Acid DMEMBJC Colorectal carcinoma Approved [670]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [671]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [203]
Methamphetamine DMPM4SK Anxiety Approved [672]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [673]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sp110 nuclear body protein (SP110)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [674]
Testosterone enanthate DMB6871 N. A. N. A. Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [675]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leucine zipper protein 2 (LUZP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [676]
Haloperidol DM96SE0 Delirium Approved [112]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [677]
Selenium DM25CGV N. A. N. A. Approved [678]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [679]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [680]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [681]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
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Drug(s) Affected By Transgelin-3 (TAGLN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [245]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [245]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [575]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [241]
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Drug(s) Affected By ATP-binding cassette sub-family C member 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [682]
Sulfinpyrazone DMEV954 Gout FA25 Approved [683]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [684]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [685]
Methotrexate DM2TEOL Anterior urethra cancer Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [686]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [624]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [135]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [687]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inositol polyphosphate 4-phosphatase type II (INPP4B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [454]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [266]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [143]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
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Drug(s) Affected By Anoctamin-3 (ANO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [312]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [241]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [241]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [316]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
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Drug(s) Affected By Protein kinase C zeta type (PRKCZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [688]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [195]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [689]
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Drug(s) Affected By RelA-associated inhibitor (PPP1R13L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [690]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
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Drug(s) Affected By Transmembrane 4 L6 family member 20 (TM4SF20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [691]
Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [623]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [692]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [638]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [693]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [694]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [695]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [264]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [696]
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Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [362]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [697]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [698]
Quercetin DM3NC4M Obesity 5B81 Approved [699]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [700]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [701]
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
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Drug(s) Affected By Ran-binding protein 17 (RANBP17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [199]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [702]
Arsenic DMTL2Y1 N. A. N. A. Approved [703]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
Drug(s) Affected By NPC intracellular cholesterol transporter 1 (NPC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [301]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [704]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Capsaicin DMGMF6V Back pain ME84.Z Approved [705]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member B1 (AKR1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [706]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [707]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [696]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [696]
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Drug(s) Affected By COX assembly mitochondrial protein 2 homolog (CMC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [186]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [708]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [709]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [197]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [296]
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Drug(s) Affected By Glutathione S-transferase Mu 1 (GSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [710]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [711]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [712]
Ethanol DMDRQZU Chronic pain MG30 Approved [713]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [304]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [304]
Methyldopa DM5I621 Hypertension BA00-BA04 Approved [714]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein SPMIP2 (SPMIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
Drug(s) Affected By Aldo-keto reductase family 1 member C3 (AKR1C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [715]
Diazepam DM08E9O Alcohol withdrawal Approved [716]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [717]
Desogestrel DM27U4Y Contraception QA21 Approved [717]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [715]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [715]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [718]
Quercetin DM3NC4M Obesity 5B81 Approved [719]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Slit homolog 3 protein (SLIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Panobinostat DM58WKG Chronic graft versus host disease Approved [241]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [167]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [720]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
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Drug(s) Affected By Microtubule-associated protein 1B (MAP1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [721]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Folic Acid DMEMBJC Colorectal carcinoma Approved [722]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Antigen peptide transporter 2 (TAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [723]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [194]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [724]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [687]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [352]
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Drug(s) Affected By Citramalyl-CoA lyase, mitochondrial (CLYBL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [725]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [726]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Limbic system-associated membrane protein (LSAMP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [479]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [234]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [312]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [702]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [727]
Arsenic DMTL2Y1 N. A. N. A. Approved [185]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [241]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [316]
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Drug(s) Affected By C-Maf-inducing protein (CMIP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [728]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [266]
Leflunomide DMR8ONJ Arthritis FA20 Approved [244]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [488]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
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Drug(s) Affected By Aldo-keto reductase family 1 member A1 (AKR1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [268]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [202]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [108]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [149]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [110]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [621]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [202]
Urethane DM7NSI0 N. A. N. A. Phase 4 [196]
Arecoline DMFJZK3 Parkinson disease 8A00.0 Phase 1 [729]
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Drug(s) Affected By EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [730]
Quercetin DM3NC4M Obesity 5B81 Approved [302]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [454]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [730]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [727]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [236]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [321]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [730]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [730]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA replication (DNA repli) TTABD5E NOUNIPROTAC Modulator [5]
Human Deoxyribonucleic acid (hDNA) TTUTN1I NOUNIPROTAC Intercalator [6]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 6 (ABCC6) DT582KR MRP6_HUMAN Substrate [7]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [8]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [9]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [10]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [11]
Cytochrome P450 1A1 (CYP1A1) DE6OQ3W CP1A1_HUMAN Substrate [11]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [11]
NADPH-cytochrome P450 reductase (CPR) DE3N2FM NCPR_HUMAN Substrate [12]
NADPH-dependent carbonyl reductase 1 (CBR1) DE9JFMC CBR1_HUMAN Substrate [13]
NADPH-dependent carbonyl reductase 3 (CBR3) DEIVKZ8 CBR3_HUMAN Substrate [14]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Actin, alpha skeletal muscle (ACTA1) OTOVGLPG ACTS_HUMAN Gene/Protein Processing [15]
Agrin (AGRN) OTWJENAZ AGRIN_HUMAN Gene/Protein Processing [16]
Aldo-keto reductase family 1 member A1 (AKR1A1) OTZT9NOW AK1A1_HUMAN Biotransformations [17]
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Biotransformations [18]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Drug Response [19]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Drug Response [20]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Gene/Protein Processing [21]
Ankyrin-2 (ANK2) OTWB4R1Y ANK2_HUMAN Gene/Protein Processing [15]
Annexin A2 (ANXA2) OTFNS0CC ANXA2_HUMAN Gene/Protein Processing [22]
Annexin A4 (ANXA4) OTUCRYXL ANXA4_HUMAN Gene/Protein Processing [16]

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