Details of Disease

General Information of Disease (ID: DISUMFQV)

Disease Name Hepatitis A virus infection
Synonyms viral hepatitis A; viral hepatitis, type A; hepatitis type A; Hepatitis A; Hepatitis A infection
Disease Class 1E50: Acute viral hepatitis
Definition
Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water.
Disease Hierarchy
DISVT5Q7: Viral hepatitis
DISUMFQV: Hepatitis A virus infection
ICD Code
ICD-11
ICD-11: 1E50.0
Disease Identifiers
MONDO ID
MONDO_0005790
MESH ID
D006506
UMLS CUI
C0019159
MedGen ID
42418
SNOMED CT ID
40468003

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 6 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Avaxim DM6BJRW Approved NA [1]
Epaxal DMGRKKV Approved NA [1]
Healive DMUZIEP Approved NA [1]
Hepatitis A vaccine DMJ3COI Approved NA [1]
Hepatyrix DMYBZJS Approved NA [1]
Vaqta DMD8HCA Approved NA [1]
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⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 43 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
APOA4 TTNC3WS Disputed Genetic Variation [2]
HNRNPA2B1 TT8UPW6 moderate Altered Expression [3]
ABCB11 TTUXCAF Strong Genetic Variation [4]
AFP TTCFEA1 Strong Biomarker [5]
APOA2 TTGQA9W Strong Biomarker [6]
BIRC7 TTHZ8TA Strong Altered Expression [7]
CD4 TTN2JFW Strong Biomarker [8]
CD58 TT5KSBY Strong Altered Expression [9]
CXCL10 TTQOVYA Strong Altered Expression [10]
CXCL2 TTZF0K2 Strong Altered Expression [11]
ESRRB TTKF0XS Strong Genetic Variation [11]
F10 TTCIHJA Strong Biomarker [12]
FGL2 TTYBS89 Strong Biomarker [13]
GPR39 TTTPCNU Strong Altered Expression [14]
GSR TTEP6RV Strong Biomarker [15]
IFNB1 TT4TZ8J Strong Biomarker [16]
IFNL1 TTM624L Strong Altered Expression [17]
IL17D TTC5LTG Strong Biomarker [18]
IL22 TTLDX4N Strong Altered Expression [19]
IL33 TT5MD4P Strong Biomarker [20]
KLRC1 TTC4IMS Strong Altered Expression [21]
LTBR TTFO0PM Strong Biomarker [22]
NR0B2 TT25A9Q Strong Biomarker [11]
NTSR1 TTTUMEP Strong Genetic Variation [23]
PARP2 TTQ4V96 Strong Altered Expression [24]
PCSK1 TTED9LZ Strong Altered Expression [25]
PKD2L1 TTAHD89 Strong Biomarker [26]
PLP2 TTK5OG6 Strong Biomarker [27]
RHD TTLCKI8 Strong Genetic Variation [28]
RNASEL TT7V0K4 Strong Altered Expression [29]
RNF34 TTEWDK1 Strong Biomarker [30]
SERPINB3 TT6QLPX Strong Altered Expression [31]
SLC10A1 TTWZRY5 Strong Biomarker [32]
SLC17A5 TTFSUIA Strong Biomarker [33]
SOCS3 TTI0ME6 Strong Altered Expression [34]
TDO2 TTXNCBV Strong Biomarker [35]
THRA TTTSEPU Strong Altered Expression [36]
TIPARP TT2FRAN Strong Altered Expression [37]
TNFRSF9 TTPW9LJ Strong Biomarker [38]
VIPR1 TTCL30I Strong Genetic Variation [39]
CRLF1 TT6YF5K Definitive Biomarker [40]
IFNL3 TTRF4Q2 Definitive Genetic Variation [41]
RIPK1 TTVJHX8 Definitive Biomarker [42]
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⏷ Show the Full List of 43 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC4A1 DTB0Q3P Limited Biomarker [43]
ABCB5 DTKVEXO Strong Altered Expression [44]
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This Disease Is Related to 4 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
AKR1D1 DEVON3M Strong Genetic Variation [45]
COLGALT2 DE8RIZD Strong Biomarker [46]
CPA4 DEXKD7J Strong Altered Expression [47]
EPHX1 DELB4KP Strong Genetic Variation [48]
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This Disease Is Related to 85 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CLTC OTBFASMA Limited Biomarker [43]
CNOT3 OT4D5Z9L Limited Biomarker [49]
ERVW-1 OTWV8DXJ Limited Genetic Variation [50]
CCDC88A OT3SSYYC Disputed Genetic Variation [51]
HAVCR1 OT184CRZ moderate Biomarker [52]
AHI1 OT8K2YWY Strong Biomarker [53]
ALDH1L1 OT15HOJX Strong Altered Expression [54]
AMELY OTVG0EXE Strong Biomarker [55]
APBA2 OTXD8ID1 Strong Posttranslational Modification [56]
ARC OTN2QQPG Strong Altered Expression [57]
ARFGEF1 OTPAU0L4 Strong Altered Expression [58]
ARHGEF5 OTUVGFT9 Strong Biomarker [59]
ARID2 OTIRJXWM Strong Altered Expression [58]
BTNL2 OTTTEMZA Strong Genetic Variation [60]
CCL16 OTOOQI1F Strong Biomarker [61]
CCL4 OT6B8P25 Strong Biomarker [62]
CD5L OTPY4WQR Strong Biomarker [63]
CD81 OTQFXNAZ Strong Genetic Variation [64]
CDSN OTQW4HV6 Strong Biomarker [65]
CLDN3 OT71MN9S Strong Biomarker [66]
COL15A1 OTTFKK18 Strong Altered Expression [67]
COMMD1 OT7WUD5R Strong Biomarker [68]
COX8A OTU0NR39 Strong Biomarker [69]
DDX18 OTKB9C3S Strong Biomarker [70]
DDX56 OTGURA53 Strong Biomarker [71]
DHX58 OT19BYB1 Strong Biomarker [72]
DLAT OT9LBJVN Strong Biomarker [73]
DMBT1 OTVNU9D9 Strong Altered Expression [74]
ECHS1 OTS0593S Strong Biomarker [75]
EMB OT67E3Q1 Strong Biomarker [76]
ESM1 OT331Y8V Strong Altered Expression [77]
FBL OTRODIE5 Strong Genetic Variation [78]
FKBP11 OTY2GC67 Strong Altered Expression [79]
FLT3LG OTU0YGC4 Strong Altered Expression [80]
FUT8 OTJJCVG1 Strong Altered Expression [61]
GGTLC1 OTWJKUHQ Strong Biomarker [81]
GOLM1 OTOZSV6O Strong Biomarker [82]
GSPT1 OT18H1B0 Strong Biomarker [83]
HAS1 OTJIAG1W Strong Biomarker [70]
HAS3 OTPM8IL8 Strong Biomarker [70]
HAVCR2 OTOL603T Strong Biomarker [84]
IFNA1 OTPMKY0L Strong Biomarker [85]
IL17C OTKXIVNQ Strong Biomarker [86]
IL17RE OTMFTNLS Strong Biomarker [86]
IL18BP OTW0LRYZ Strong Biomarker [87]
IL27 OTIS3OF8 Strong Biomarker [18]
KIF1B OTI1XQTO Strong Genetic Variation [88]
KLRB1 OTQ2959Y Strong Biomarker [89]
KRT23 OTQW6UAG Strong Biomarker [90]
LAMP3 OTN0XL3W Strong Biomarker [91]
LTBP2 OTS88GSD Strong Biomarker [92]
MAVS OTTQ0J64 Strong Biomarker [93]
MICA OTPEIEAR Strong Genetic Variation [94]
NBAS OTW9IBRI Strong Genetic Variation [95]
NCKIPSD OT24UORN Strong Biomarker [53]
NELFE OTL4E94L Strong Altered Expression [96]
NSG1 OTRIMA50 Strong Altered Expression [97]
OXA1L OTS0BFRD Strong Genetic Variation [98]
PDLIM5 OTLQVV22 Strong Biomarker [99]
PGAM5 OT6Q5M0C Strong Altered Expression [100]
PIGR OT6GLSUL Strong Biomarker [101]
RHOF OTPA3F8Q Strong Biomarker [30]
RIT2 OTSNYG0D Strong Biomarker [102]
RO60 OTLGM5A8 Strong Biomarker [103]
SARS1 OTFKXQ1O Strong Biomarker [104]
SARS2 OTU4T99W Strong Biomarker [104]
SERPINB4 OT88LHZ8 Strong Altered Expression [31]
SGMS1 OTZQE7PW Strong Biomarker [105]
SMARCA5 OT5GR4Z2 Strong Biomarker [5]
SON OT9VWV18 Strong Biomarker [106]
SPAG9 OT45AHMB Strong Altered Expression [107]
SPINT1 OT1CLR5L Strong Biomarker [108]
SYCE1L OTXU44F3 Strong Genetic Variation [109]
TCEAL1 OTAPG2L5 Strong Altered Expression [97]
TIMELESS OTD8DCBJ Strong Biomarker [59]
TNFAIP8L2 OTII0RM0 Strong Altered Expression [110]
TRIM55 OTY5YQFX Strong Altered Expression [111]
TRIM63 OTUSWA74 Strong Altered Expression [111]
CRNKL1 OTWBQNGU Definitive Biomarker [40]
EXT1 OTRPALJK Definitive Biomarker [112]
IVNS1ABP OTYHL4I7 Definitive Biomarker [113]
MYOM2 OTD2UOXW Definitive Biomarker [114]
RBM45 OTWTHD77 Definitive Genetic Variation [115]
SERPINA7 OTUYVTSU Definitive Biomarker [116]
SETBP1 OTKGCOSR Definitive Biomarker [117]
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⏷ Show the Full List of 85 DOT(s)

References

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34 Impairment of GH/IGF-1 Axis in the Liver of Patients with HCV-Related Chronic Hepatitis.Horm Metab Res. 2018 Feb;50(2):145-151. doi: 10.1055/s-0043-118911. Epub 2017 Sep 18.
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41 Differential distribution of IL28B.rs12979860 single-nucleotide polymorphism among Egyptian healthcare workers with and without a hepatitis C virus-specific cellular immune response.Arch Virol. 2015 Jul;160(7):1741-50. doi: 10.1007/s00705-015-2446-7. Epub 2015 May 15.
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43 Upregulation of CXCR3 expression on CD8+ T cells due to the pervasive influence of chronic hepatitis B and C virus infection.Hum Immunol. 2013 Aug;74(8):899-906. doi: 10.1016/j.humimm.2013.04.017. Epub 2013 Apr 30.
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79 Identification of FKBP11 as a biomarker for hepatocellular carcinoma.Anticancer Res. 2013 Jun;33(6):2763-9.
80 Ratios of T-helper 2 Cells to T-helper 1 Cells and Cytokine Levels in Patients with Hepatitis B.Chin Med J (Engl). 2017 Aug 5;130(15):1810-1815. doi: 10.4103/0366-6999.211541.
81 Hepatic Lesions Associated With McCune Albright Syndrome.J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):e54-e57. doi: 10.1097/MPG.0000000000002266.
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