Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM37C0)

Drug Name
RESORCINOL Drug Info
Synonyms
resorcinol; 108-46-3; 1,3-Benzenediol; Resorcin; 1,3-Dihydroxybenzene; benzene-1,3-diol; m-Hydroquinone; 3-Hydroxyphenol; m-Hydroxyphenol; m-Dihydroxybenzene; Resorcine; m-Dioxybenzene; m-Benzenediol; Dihydroxybenzol; Resorzin; Developer O; Developer R; Developer RS; Fouramine RS; Fourrine EW; Pelagol RS; Pelagol Grey RS; Resorcinolum; Fourrine 79; Nako TGG; Durafur developer G; Phenol, m-hydroxy-; C.I. Developer 4; Benzene, m-dihydroxy-; C.I. Oxidation Base 31; Rcra waste number U201; Sulforcin; Rezamid; Resorcino; Benzene, 1,3-dihydroxy-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5054
ChEBI ID
CHEMBL27810
CAS Number
CAS 108-46-3
TTD Drug ID
DMM37C0
INTEDE Drug ID
DR2304

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Carbonic anhydrase XII (CA-XII)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [2]
Sulfamylon DMIO1K0 Bacterial infection 1A00-1C4Z Approved [6]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [7]
PARABEN DMEW5Z8 N. A. N. A. Phase 3 [8]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [7]
Coumate DMVKW0N Breast cancer 2C60-2C65 Phase 2 [9]
FERULIC ACID DMJC7NF Discovery agent N.A. Patented [8]
ELLAGIC ACID DMX8BS5 Discovery agent N.A. Investigative [8]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [10]
CATECHIN DMY38SB Discovery agent N.A. Investigative [7]
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Drug(s) Targeting Carbonic anhydrase II (CA-II)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [2]
Sulfamylon DMIO1K0 Bacterial infection 1A00-1C4Z Approved [6]
Dorzolamide DMA17D0 Ocular hypertension 9C61.01 Approved [11]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [12]
Ethoxzolamide DMVO4ED Glaucoma/ocular hypertension 9C61 Approved [13]
Dichlorphenamide DMH7IDQ Chronic glaucoma 9C61.0Z Approved [13]
Cyclothiazide DMJ4AWC Congestive heart failure BD10 Approved [14]
Ethinamate DMK57GB Insomnia 7A00-7A0Z Approved [15]
Benzthiazide DMQWZ0H High blood pressure BA00 Approved [16]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [7]
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Drug(s) Targeting Carbonic anhydrase XIV (CA-XIV)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulfamylon DMIO1K0 Bacterial infection 1A00-1C4Z Approved [17]
TRIENTINE DMD2WPG Inborn error of metabolism 5C50-5C59 Approved [18]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [7]
PARABEN DMEW5Z8 N. A. N. A. Phase 3 [8]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [7]
Coumate DMVKW0N Breast cancer 2C60-2C65 Phase 2 [9]
FERULIC ACID DMJC7NF Discovery agent N.A. Patented [8]
SPERMINE DMD4BFY N. A. N. A. Terminated [18]
ELLAGIC ACID DMX8BS5 Discovery agent N.A. Investigative [8]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [10]
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Drug(s) Targeting Carbonic anhydrase (CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [19]
Sulfamylon DMIO1K0 Bacterial infection 1A00-1C4Z Approved [20]
Quinethazone DMWCOSR Hypertension BA00-BA04 Approved [21]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [7]
PARABEN DMEW5Z8 N. A. N. A. Phase 3 [8]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [7]
Coumate DMVKW0N Breast cancer 2C60-2C65 Phase 2 [9]
SULFAMIDE DMMAS3K N. A. N. A. Phase 1 [22]
FERULIC ACID DMJC7NF Discovery agent N.A. Patented [8]
PMID30074415-Compound-21 DM3NPOU N. A. N. A. Patented [23]
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Drug(s) Targeting Prostaglandin G/H synthase 1 (COX-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [24]
Naproxen DMZ5RGV Bursitis Approved [25]
Mesalazine DMOL5IU Diverticulitis Approved [26]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [27]
Bromfenac DMKB79O Pain MG30-MG3Z Approved [28]
Aminosalicylic Acid DMENSL5 Crohn disease DD70 Approved [29]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [30]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [29]
Suprofen DMKXJZ7 Miosis LA11.62 Approved [31]
Gamma-Homolinolenic acid DMSXKYG Malnutrition 5B50-5B71 Approved [32]
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Drug(s) Metabolized By Glucansucrase (gtf106B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sucrose DMVWUCF Discovery agent N.A. Investigative [33]
CATECHOL DML0YEK Discovery agent N.A. Investigative [34]
ETHYLGALLATE DMJ6PB8 Discovery agent N.A. Investigative [35]
PYROGALLOL DMG5KDY Discovery agent N.A. Investigative [36]
Drug(s) Affected By Golgin subfamily A member 8A (GOLGA8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [41]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [42]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [46]
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Drug(s) Affected By Uncharacterized protein C17orf100 (C17ORF100)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [47]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [52]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [53]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
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Drug(s) Affected By Class E basic helix-loop-helix protein 40 (BHLHE40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [58]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [60]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [61]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
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Drug(s) Affected By Suppressor of cytokine signaling 7 (SOCS7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [66]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [66]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
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Drug(s) Affected By Transmembrane gamma-carboxyglutamic acid protein 1 (PRRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [72]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [59]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [73]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [74]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Selenium DM25CGV N. A. N. A. Approved [78]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [79]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [79]
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Drug(s) Affected By Sphingolipid delta(4)-desaturase DES1 (DEGS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [85]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [86]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [87]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [59]
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Drug(s) Affected By Membrane-associated progesterone receptor component 2 (PGRMC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Folic Acid DMEMBJC Colorectal carcinoma Approved [90]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [85]
Arsenic DMTL2Y1 N. A. N. A. Approved [93]
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Drug(s) Affected By Mitogen-activated protein kinase kinase kinase 13 (MAP3K13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [96]
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Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [97]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [98]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [99]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [101]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [102]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [104]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [105]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [106]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [104]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Fluoxetine DM3PD2C Bipolar depression Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [105]
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Drug(s) Affected By Pre-mRNA-processing factor 17 (CDC40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [107]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [107]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
AMINOHIPPURIC ACID DMUN54G Discovery agent N.A. Investigative [108]
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Drug(s) Affected By Leupaxin (LPXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [112]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
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Drug(s) Affected By Frizzled-7 (FZD7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [66]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [115]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [117]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
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Drug(s) Affected By Serine/threonine-protein kinase 17B (STK17B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [121]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [122]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Menthol DMG2KW7 Back pain ME84.Z Approved [123]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
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Drug(s) Affected By Transmembrane and coiled-coil domains protein 1 (TMCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [126]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
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Drug(s) Affected By D-glucuronyl C5-epimerase (GLCE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [126]
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Drug(s) Affected By Protein FAM13A (FAM13A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Ethanol DMDRQZU Chronic pain MG30 Approved [128]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [129]
Vandetanib DMRICNP Solid tumour/cancer 2A00-2F9Z Approved [130]
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Drug(s) Affected By Starch-binding domain-containing protein 1 (STBD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [132]
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Drug(s) Affected By Luc7-like protein 3 (LUC7L3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Testosterone enanthate DMB6871 N. A. N. A. Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [81]
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Drug(s) Affected By Heat shock 70 kDa protein 4L (HSPA4L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Ethanol DMDRQZU Chronic pain MG30 Approved [128]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-1 (CLDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [139]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acylphosphatase-1 (ACYP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-enolase (ENO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Estrone DM5T6US Acne vulgaris ED80 Approved [143]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [144]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [145]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [146]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [147]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [148]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [104]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [106]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Fluoxetine DM3PD2C Bipolar depression Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ski-like protein (SKIL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [151]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Arsenic DMTL2Y1 N. A. N. A. Approved [152]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [153]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [154]
Selenium DM25CGV N. A. N. A. Approved [81]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [155]
Etretinate DM2CZFA Keratosis ED56 Approved [156]
Methotrexate DM2TEOL Anterior urethra cancer Approved [157]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [158]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [159]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [160]
Quercetin DM3NC4M Obesity 5B81 Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 1 (DNAJB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Gefitinib DM15F0X Colon adenocarcinoma Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [165]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [134]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [166]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [167]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [170]
Quercetin DM3NC4M Obesity 5B81 Approved [171]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [172]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [173]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [174]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [94]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [76]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [177]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [178]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase FRK (FRK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [61]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [180]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [181]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent creatine transporter 1 (SLC6A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [182]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ampicillin DMHWE7P Acute epiglottitis Approved [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serpin B9 (SERPINB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [184]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [184]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [185]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [172]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Clozapine DMFC71L Schizophrenia 6A20 Approved [186]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [187]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sestrin-3 (SESN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Capsaicin DMGMF6V Back pain ME84.Z Approved [190]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bladder cancer-associated protein (BLCAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [192]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H3.1 (H3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [195]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-3 (ID3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [196]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [197]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [173]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [198]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [199]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By A-kinase anchor protein 12 (AKAP12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [173]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nexilin (NEXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [201]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BMP and activin membrane-bound inhibitor homolog (BAMBI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [202]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 5 (SRSF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [204]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Benzatropine DMF7EXL Parkinsonian disorder Approved [205]
Clozapine DMFC71L Schizophrenia 6A20 Approved [205]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Fluoxetine DM3PD2C Bipolar depression Approved [207]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [208]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [165]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [209]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 6 group A member 1 (NR6A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [210]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [211]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [212]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [66]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [66]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 0 group B member 2 (NR0B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [213]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [104]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [214]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [97]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [104]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [105]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [215]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Fluoxetine DM3PD2C Bipolar depression Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription initiation factor TFIID subunit 7 (TAF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [216]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ethanol DMDRQZU Chronic pain MG30 Approved [217]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [132]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [187]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 5 (DUSP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [218]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [146]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [134]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [219]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Ethanol DMDRQZU Chronic pain MG30 Approved [217]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [134]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Putative deoxyribonuclease TATDN3 (TATDN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [220]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Renal cancer differentiation gene 1 protein (C4ORF46)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [221]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [222]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spindlin-4 (SPIN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [222]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [43]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [224]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [59]
OXYQUINOLINE DMZVS9Y Discovery agent N.A. Investigative [37]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By BRO1 domain-containing protein BROX (BROX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [109]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Protein lin-54 homolog (LIN54)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [216]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Leucine-rich repeats and immunoglobulin-like domains protein 3 (LRIG3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [226]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [37]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Activating transcription factor 7-interacting protein 1 (ATF7IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Volume-regulated anion channel subunit LRRC8D (LRRC8D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [132]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [86]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related GTP-binding protein A (RRAGA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [227]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [228]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [187]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FAST kinase domain-containing protein 5, mitochondrial (FASTKD5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [230]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [231]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Chemokine-like protein TAFA-5 (TAFA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [43]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin repeat domain-containing protein 37 (ANKRD37)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [37]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By KH homology domain-containing protein 4 (KHDC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [232]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic solute transporter subunit beta (SLC51B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [196]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [233]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [208]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [234]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [235]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [233]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [236]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase TRIM50 (TRIM50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [237]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [237]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [238]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [238]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By ERO1-like protein beta (ERO1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [239]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [87]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [240]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [241]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Choline transporter-like protein 2 (SLC44A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [243]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ethanol DMDRQZU Chronic pain MG30 Approved [217]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [244]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein p53-inducible nuclear protein 2 (TP53INP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Capsaicin DMGMF6V Back pain ME84.Z Approved [190]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [56]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [245]
Arsenic DMTL2Y1 N. A. N. A. Approved [246]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [87]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [216]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [247]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [222]
Milchsaure DM462BT Pruritus EC90 Investigative [248]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-responsive transcription factor (CARF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [126]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [249]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Prostaglandin reductase 3 (PTGR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [222]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-42 (RAB42)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [45]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [241]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein mL50 (MRPL50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [250]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [251]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By EP300-interacting inhibitor of differentiation 2 (EID2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [192]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein FAM241A (FAM241A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [56]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [42]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [91]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [240]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G patch domain-containing protein 11 (GPATCH11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [222]
Milchsaure DM462BT Pruritus EC90 Investigative [248]
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Drug(s) Affected By Junction-mediating and -regulatory protein (JMY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch-like protein 23 (KLHL23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [252]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [253]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Major facilitator superfamily domain-containing protein 9 (MFSD9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [59]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [255]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By NFATC2-interacting protein (NFATC2IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [216]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Testosterone enanthate DMB6871 N. A. N. A. Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [256]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [222]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paraneoplastic antigen Ma1 (PNMA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Benzatropine DMF7EXL Parkinsonian disorder Approved [205]
Clozapine DMFC71L Schizophrenia 6A20 Approved [205]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 36 (FBXO36)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [86]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [257]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Methylcytosine dioxygenase TET1 (TET1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [259]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [226]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein CXorf38 (CXORF38)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [216]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [121]
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Drug(s) Affected By Arginine/serine-rich protein PNISR (PNISR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [232]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Bortezomib DMNO38U Leukemia Approved [252]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 170A (TMEM170A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [121]
GALLICACID DM6Y3A0 Discovery agent N.A. Investigative [260]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Uncharacterized protein C4orf3 (C4ORF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [146]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Bortezomib DMNO38U Leukemia Approved [252]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nanos homolog 1 (NANOS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [165]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [165]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [252]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [91]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Jun dimerization protein 2 (JDP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ampicillin DMHWE7P Acute epiglottitis Approved [37]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [256]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By T-complex protein 1 subunit zeta-2 (CCT6B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [257]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [247]
Drug(s) Affected By Protein NDRG1 (NDRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [261]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [262]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [263]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [57]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [256]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho-related GTP-binding protein Rho6 (RND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [201]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amyloid beta precursor protein binding family B member 2 (APBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [113]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [126]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine palmitoyltransferase small subunit A (SPTSSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [253]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [132]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [46]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arrestin domain-containing protein 3 (ARRDC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Modulator of apoptosis 1 (MOAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Menthol DMG2KW7 Back pain ME84.Z Approved [123]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [264]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [265]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small integral membrane protein 19 (SMIM19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [47]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [266]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dynein light chain 2, cytoplasmic (DYNLL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [267]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [87]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine dehydratase-like (SDSL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [59]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [43]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [268]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [269]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ataxin-7-like protein 3B (ATXN7L3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [38]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [251]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [270]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 169 (TMEM169)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Folic Acid DMEMBJC Colorectal carcinoma Approved [41]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [59]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [216]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box/LRR-repeat protein 20 (FBXL20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [151]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C5orf34 (C5ORF34)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [272]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leukocyte receptor cluster member 8 (LENG8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [208]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cbp/p300-interacting transactivator 2 (CITED2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [214]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [202]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein LLP homolog (LLPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Arginine/serine-rich protein 1 (RSRP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [273]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [113]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collectin-11 (COLEC11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [170]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [121]
Drug(s) Affected By Homeobox protein Hox-D1 (HOXD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [132]
Ethanol DMDRQZU Chronic pain MG30 Approved [217]
Ampicillin DMHWE7P Acute epiglottitis Approved [37]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [4]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 15 (DUSP15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Bortezomib DMNO38U Leukemia Approved [252]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Drug(s) Affected By Pinin (PNN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [274]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [274]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [113]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Regulator of cell cycle RGCC (RGCC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [56]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [275]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ampicillin DMHWE7P Acute epiglottitis Approved [37]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [129]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein Pegasus (IKZF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [252]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By tRNA (NSUN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [276]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [249]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 SUMO-protein ligase KIAA1586 (KIAA1586)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [277]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [188]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [269]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By O-phosphoseryl-tRNA(Sec) selenium transferase (SEPSECS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [278]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [59]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycerophosphocholine phosphodiesterase GPCPD1 (GPCPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Folic Acid DMEMBJC Colorectal carcinoma Approved [41]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Arsenic DMTL2Y1 N. A. N. A. Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [67]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenosine 5'-monophosphoramidase HINT3 (HINT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [276]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [221]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [193]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein 12 (RBM12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [132]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [53]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [96]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch-like protein 11 (KLHL11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [266]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [271]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RLIM (RLIM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [280]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [230]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [40]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase FANCL (FANCL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [66]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [85]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G patch domain-containing protein 2 (GPATCH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [109]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [221]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C14orf119 (C14ORF119)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [282]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Gypsy retrotransposon integrase-like protein 1 (GIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [45]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [283]
Milchsaure DM462BT Pruritus EC90 Investigative [248]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [109]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Inhibitor of growth protein 3 (ING3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [280]
Arsenic DMTL2Y1 N. A. N. A. Approved [267]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [45]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [187]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily C member 27 (DNAJC27)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [151]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [216]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [230]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Protein Smaug homolog 1 (SAMD4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [84]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [70]
Arsenic DMTL2Y1 N. A. N. A. Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial import inner membrane translocase subunit Tim10 B (TIMM10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [250]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Urethane DM7NSI0 N. A. N. A. Phase 4 [51]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [284]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [285]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible lipid droplet-associated protein (HILPDA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Methotrexate DM2TEOL Anterior urethra cancer Approved [200]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [200]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [209]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [202]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Methyltransferase N6AMT1 (N6AMT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [286]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [275]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-induced gene 2 protein (INSIG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [120]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [146]
Ethanol DMDRQZU Chronic pain MG30 Approved [128]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [146]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [59]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [252]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [280]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [225]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [50]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 30 (FBXO30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [287]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [146]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromelysin-1 (MMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [288]
Fluvastatin DM4MDJY Arteriosclerosis BD40 Approved [288]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [288]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [288]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [289]
Methotrexate DM2TEOL Anterior urethra cancer Approved [290]
Quercetin DM3NC4M Obesity 5B81 Approved [291]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [292]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromelysin-2 (MMP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [103]
Methotrexate DM2TEOL Anterior urethra cancer Approved [200]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [293]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [184]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [200]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [184]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Haloperidol DM96SE0 Delirium Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [294]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [295]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [296]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [196]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [297]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [298]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [299]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [300]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [299]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serpin B3 (SERPINB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [82]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [301]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [302]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [5]
Seocalcitol DMKL9QO Rickets 5B57 Phase 3 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [68]
EUGENOL DM7US1H Discovery agent N.A. Patented [5]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [303]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [304]
Diazepam DM08E9O Alcohol withdrawal Approved [305]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [306]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [304]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [304]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [293]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [307]
Ethacrynic acid DM60QMR Edema MG29 Approved [306]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [304]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-1 (ID1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [308]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [196]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [309]
Selenium DM25CGV N. A. N. A. Approved [81]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [311]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [43]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CD83 antigen (CD83)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [313]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [65]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [314]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [315]
Leflunomide DMR8ONJ Arthritis FA20 Approved [63]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [48]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [316]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [317]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [318]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [308]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Capsaicin DMGMF6V Back pain ME84.Z Approved [190]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [111]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [319]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 4 (DNAJB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [163]
Selenium DM25CGV N. A. N. A. Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [37]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [320]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [165]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [61]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [321]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [163]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Carbonic anhydrase (CA) TTUNARX NOUNIPROTAC Inhibitor [2]
Carbonic anhydrase II (CA-II) TTANPDJ CAH2_HUMAN Inhibitor [2]
Carbonic anhydrase XII (CA-XII) TTSYM0R CAH12_HUMAN Inhibitor [2]
Carbonic anhydrase XIV (CA-XIV) TTEYTKG CAH14_HUMAN Inhibitor [2]
Prostaglandin G/H synthase 1 (COX-1) TT8NGED PGH1_HUMAN Inhibitor [1]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Glucansucrase (gtf106B) Main DME DEWRN24 Q5SBN3_LACRE Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) OT25JBA3 F263_HUMAN Gene/Protein Processing [4]
A-kinase anchor protein 12 (AKAP12) OTCVRDDX AKA12_HUMAN Gene/Protein Processing [4]
Activating transcription factor 7-interacting protein 1 (ATF7IP) OTU6ZA7F MCAF1_HUMAN Gene/Protein Processing [4]
Acylphosphatase-1 (ACYP1) OTR77NZD ACYP1_HUMAN Gene/Protein Processing [4]
Adenosine 5'-monophosphoramidase HINT3 (HINT3) OTJGDLB6 HINT3_HUMAN Gene/Protein Processing [4]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [4]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [5]
Amyloid beta precursor protein binding family B member 2 (APBB2) OT1VD51B APBB2_HUMAN Gene/Protein Processing [4]
Ankyrin repeat domain-containing protein 37 (ANKRD37) OTXSY21F ANR37_HUMAN Gene/Protein Processing [4]
Arginine/serine-rich protein 1 (RSRP1) OTOAZLCL RSRP1_HUMAN Gene/Protein Processing [4]

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115 DNA methylation inhibits p53-mediated survivin repression. Oncogene. 2009 May 14;28(19):2046-50. doi: 10.1038/onc.2009.62. Epub 2009 Apr 13.
116 Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. Tumour Biol. 2011 Oct;32(5):965-76.
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