Details of Disease

Disease Name

Wilms tumor

Wilms tumor (nephroblastoma); Wilms tumour (nephroblastoma); Wilms tumor; Wilms' tumor; Wilms' tumour

Definition

An embryonal neoplasm characterized by the presence of epithelial, mesenchymal, and blastema components. The vast majority of cases arise from the kidney. A small number of cases with morphologic features resembling Wilms tumor of the kidney have been reported arising from the ovary and the cervix.

Disease Hierarchy

DIS5MQSB: Embryonal neoplasm

:

DISB6T16: Wilms tumor

Disease Identifiers

MONDO ID

MONDO_0006058

MESH ID

D009396

UMLS CUI

C0027708

OMIM ID

194070

MedGen ID

10221

HPO ID

HP:0002667

Orphanet ID

654

SNOMED CT ID

25081006

General Information of Disease (ID: DISB6T16)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 3 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Dactinomycin	DM2YGNW	Approved	Small molecular drug	[1]
Doxorubicin	DMVP5YE	Approved	Small molecular drug	[2]
Vincristine	DMINOX3	Approved	Small molecular drug	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 58 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
CD34	TTZAVYN	Limited	Biomarker	[4]
HCRTR1	TT60Q8D	Limited	Biomarker	[5]
LIN28A	TTO50LN	Limited	Biomarker	[6]
LMO2	TTFX379	Limited	Biomarker	[7]
NPM1	TTHBS98	Limited	Genetic Variation	[8]
NR0B1	TTTK36V	Limited	Biomarker	[9]
S1PR2	TTVSMOH	Limited	Biomarker	[10]
SLC38A2	TTUSC27	Limited	Biomarker	[11]
TBXA2R	TT2O84V	Limited	Altered Expression	[12]
MKNK1	TTEZAUX	Disputed	Biomarker	[13]
SRPK1	TTU3WV6	Disputed	Biomarker	[14]
MTTP	TTUS1RD	moderate	Biomarker	[15]
ABCB4	TTJUXV6	Strong	Biomarker	[16]
ABL1	TT6B75U	Strong	Altered Expression	[17]
ACVR2B	TTLFRKS	Strong	Altered Expression	[18]
BMP7	TTKOBRA	Strong	Altered Expression	[19]
BRCA2	TTUARD6	Strong	Biomarker	[20]
CDKN1C	TTBSUAR	Strong	Genetic Variation	[21]
CHEK2	TT9ABMF	Strong	CausalMutation	[22]
COL6A3	TT5WCAH	Strong	Biomarker	[23]
CSF3R	TTC70AJ	Strong	Altered Expression	[24]
DICER1	TTTEOPU	Strong	Biomarker	[25]
E2F3	TTWIJYH	Strong	Altered Expression	[26]
FGF8	TTIUF3J	Strong	Biomarker	[27]
FLT3	TTGJCWZ	Strong	Genetic Variation	[28]
FZD7	TTUQMO5	Strong	Biomarker	[29]
GLIPR1	TTEQF1O	Strong	Biomarker	[30]
HLA-A	TTHONFT	Strong	Biomarker	[31]
KCNQ1	TT846HF	Strong	Genetic Variation	[32]
LHCGR	TT2O4W9	Strong	Altered Expression	[33]
MAP3K4	TT1RSX7	Strong	Biomarker	[23]
MAPK8IP1	TTXKZ8Q	Strong	Altered Expression	[34]
MUC16	TTC1PS3	Strong	Altered Expression	[35]
NCAM1	TTVXPHT	Strong	Biomarker	[36]
NES	TTHZ752	Strong	Altered Expression	[37]
PCSK9	TTNIZ2B	Strong	Genetic Variation	[38]
PDGFA	TTSM78N	Strong	Biomarker	[39]
PMEL	TT8MK59	Strong	Biomarker	[40]
PRAME	TTPH7T0	Strong	Altered Expression	[41]
PRTN3	TT5MLC4	Strong	Genetic Variation	[42]
RARA	TTW38KT	Strong	Altered Expression	[43]
RECK	TTRZBW7	Strong	Posttranslational Modification	[44]
RGS6	TTJ96M8	Strong	Altered Expression	[45]
RNMT	TTG45HY	Strong	Biomarker	[46]
RRM1	TTWP0NS	Strong	Biomarker	[47]
SCT	TTOBVIN	Strong	Biomarker	[48]
SLC8A1	TTCF82X	Strong	Altered Expression	[49]
SPRY1	TT0PSN6	Strong	Biomarker	[50]
SRD5A2	TTT02K8	Strong	Altered Expression	[33]
TOP2A	TTCGY2K	Strong	Biomarker	[51]
TRIM28	TTQ2BKV	Strong	Biomarker	[52]
TRIM37	TTAMCSL	Strong	Genetic Variation	[53]
TSPAN7	TTMT6VE	Strong	Altered Expression	[54]
VHL	TTEMWSD	Strong	Biomarker	[55]
ZNF224	TT1CDXL	Strong	Altered Expression	[56]
FSHB	TT13GFV	Definitive	Genetic Variation	[47]
MAP3K7	TTJQT60	Definitive	Biomarker	[57]
MDK	TTV8UE7	Definitive	Biomarker	[58]
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⏷ Show the Full List of 58 DTT(s)

This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
THOP1	DE95LJC	Strong	Altered Expression	[59]
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This Disease Is Related to 164 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
AATF	OT1QOKLD	Limited	Altered Expression	[60]
BASP1	OTF4VS5G	Limited	Altered Expression	[61]
BLCAP	OTGJVU0C	Limited	Altered Expression	[62]
CCNA1	OTX4HD45	Limited	Biomarker	[63]
CDX1	OTOHTMJE	Limited	Biomarker	[63]
CORO1A	OTVAZOHC	Limited	Biomarker	[64]
CRLS1	OT7XNL0K	Limited	Altered Expression	[65]
CTCF	OT8ZB70U	Limited	Altered Expression	[66]
CTNNA1	OTFC725Z	Limited	Genetic Variation	[67]
CTNNA3	OT9Z0P1E	Limited	Genetic Variation	[67]
DIS3L2	OTWABM04	Limited	Biomarker	[68]
EGR2	OTAVQ78J	Limited	Biomarker	[69]
ELP4	OTP5GZ9V	Limited	Genetic Variation	[70]
EYA1	OTHU807A	Limited	Altered Expression	[71]
FLII	OT7G9JG6	Limited	Biomarker	[72]
FRS2	OTDMD800	Limited	Biomarker	[73]
FZD1	OTZATHVS	Limited	Biomarker	[29]
FZD5	OTXFFY56	Limited	Biomarker	[29]
GLRA2	OTDQ0KW7	Limited	Biomarker	[74]
HNRNPL	OT0DJX74	Limited	Biomarker	[75]
INTS2	OT2N5TCK	Limited	Biomarker	[76]
LAMB2	OT71OI2Y	Limited	Biomarker	[77]
LUZP2	OTGGOSPW	Limited	Biomarker	[78]
MSX1	OT5U41ZP	Limited	Biomarker	[79]
MYOD1	OTV2S79X	Limited	Genetic Variation	[63]
NAP1L4	OTUEG3QY	Limited	Biomarker	[80]
NCKIPSD	OT24UORN	Limited	Biomarker	[81]
NDC80	OTS7D306	Limited	Biomarker	[82]
NNAT	OTNRLO7G	Limited	Altered Expression	[62]
NPHS1	OT21JD3P	Limited	Altered Expression	[83]
OSR1	OTB19LEQ	Limited	Altered Expression	[84]
PHF2	OTJCIQR2	Limited	Biomarker	[85]
PHLDA1	OTFTWMIQ	Limited	Altered Expression	[86]
PHLDA2	OTMV9DPP	Limited	Altered Expression	[86]
PIAS4	OTB7SVMZ	Limited	Biomarker	[87]
PIEZO1	OTBG1FU4	Limited	Altered Expression	[88]
PKHD1	OTAH8SMF	Limited	Genetic Variation	[89]
PLCE1	OTJISZOX	Limited	Genetic Variation	[77]
PLCG2	OTGVC9MY	Limited	Altered Expression	[90]
PPBP	OT1FHGQS	Limited	Biomarker	[80]
PPP2R1A	OTYA3GB4	Limited	Genetic Variation	[91]
PRM1	OT6HWA11	Limited	Biomarker	[12]
QPRT	OT6SKKLL	Limited	Biomarker	[92]
RAB40B	OTCA9ZF5	Limited	Genetic Variation	[63]
RASSF7	OT0V4EIZ	Limited	Biomarker	[93]
RBP2	OTR8QG5V	Limited	Altered Expression	[94]
RNF40	OTC8SDA3	Limited	Biomarker	[95]
RTL8C	OTJA37NU	Limited	Biomarker	[63]
SALL1	OTYYZGLH	Limited	Altered Expression	[96]
SALL2	OTQWI68Q	Limited	Altered Expression	[97]
SAT2	OT28QL7H	Limited	Biomarker	[11]
SIX2	OTYOVGSC	Limited	Biomarker	[23]
SIX3	OTP5E3VU	Limited	Biomarker	[87]
SMR3B	OTL5HNM8	Limited	Biomarker	[98]
SMTN	OT4R2TYK	Limited	Altered Expression	[99]
SOSTDC1	OTAKDNSM	Limited	Genetic Variation	[100]
TES	OTL8PP6V	Limited	Biomarker	[101]
TIMP4	OT8A68SW	Limited	Biomarker	[102]
ATG4B	OTQ4RNRM	Disputed	Altered Expression	[103]
BRINP1	OTEUVSCP	Disputed	Genetic Variation	[104]
CD151	OTF3UZS7	Disputed	Biomarker	[105]
DES	OTI09KBW	Disputed	Altered Expression	[106]
FXR1	OTEMQ1SR	Disputed	Biomarker	[107]
NKX6-1	OT5QC0BF	Disputed	Genetic Variation	[104]
NPHP1	OTZHCFFQ	Disputed	Genetic Variation	[108]
PFN1	OTHTGA1H	Disputed	Biomarker	[109]
SYCP3	OTKOF54H	Disputed	Altered Expression	[110]
SYNPO	OTICDJAB	Disputed	Altered Expression	[106]
BCR	OTCN76C1	moderate	Biomarker	[111]
POU6F2	OTNSW95F	moderate	Biomarker	[112]
ACTN4	OTCNZAJ5	Strong	Biomarker	[113]
AMER2	OTA1Q07C	Strong	Biomarker	[114]
AMH	OT5FH4BD	Strong	Altered Expression	[115]
APOBEC3A	OTYO6F5P	Strong	Genetic Variation	[116]
ARHGAP24	OTCQCEZS	Strong	Altered Expression	[117]
ARHGEF1	OTXU4HBW	Strong	Altered Expression	[118]
ARID1A	OTRWDV3P	Strong	Biomarker	[23]
ASXL1	OTX931AW	Strong	Biomarker	[23]
BAALC	OTUZSRVF	Strong	Genetic Variation	[119]
BARD1	OTTC0Z9Y	Strong	Genetic Variation	[120]
BBS9	OT23V9YF	Strong	Biomarker	[121]
BCOR	OTG013AX	Strong	Biomarker	[23]
BCORL1	OTPTFQN5	Strong	Biomarker	[23]
BCS1L	OT5PY5CY	Strong	Genetic Variation	[122]
BUB1B	OT8KME51	Strong	Genetic Variation	[123]
CALB2	OTSNMCG9	Strong	Biomarker	[124]
CBFB	OTIAC6W4	Strong	Altered Expression	[15]
CCN3	OTOW5YL4	Strong	Biomarker	[125]
CD2AP	OTC76KQM	Strong	Altered Expression	[126]
CDC73	OT6JASZ1	Strong	Genetic Variation	[127]
CITED1	OTUJQ3VL	Strong	Biomarker	[37]
CLYBL	OTXZLTST	Strong	Genetic Variation	[128]
CMIP	OTZN8Z4A	Strong	Altered Expression	[129]
CRABP2	OTY01V9G	Strong	Biomarker	[43]
CTR9	OTP151PZ	Strong	Genetic Variation	[130]
DDX1	OT3U8FD0	Strong	Biomarker	[131]
DGCR8	OT62LXE4	Strong	Biomarker	[132]
DLG2	OTQ3BD8U	Strong	Genetic Variation	[38]
DROSHA	OTCE68KZ	Strong	Genetic Variation	[132]
DTX4	OTGX30AO	Strong	Genetic Variation	[133]
EGR3	OTGPJIRA	Strong	Altered Expression	[50]
EWSR1	OT7SRHV3	Strong	Biomarker	[134]
FANCB	OTMZTXB5	Strong	Altered Expression	[135]
FBXW8	OTJG15EO	Strong	Biomarker	[136]
FIBP	OTI7131S	Strong	Biomarker	[137]
GATA1	OTX1R7O1	Strong	Biomarker	[138]
GATA2	OTBP2QQ2	Strong	Biomarker	[139]
HACE1	OTEZULKD	Strong	Genetic Variation	[140]
HOXB4	OTH1HRW5	Strong	Altered Expression	[141]
HOXD10	OT0NOWU2	Strong	Altered Expression	[142]
HTRA2	OTC7616F	Strong	Biomarker	[143]
IBTK	OTB2GM4G	Strong	Genetic Variation	[118]
IFI16	OT4SPU0U	Strong	Biomarker	[144]
IRX3	OTLJ48FG	Strong	Altered Expression	[145]
IRX5	OT05J514	Strong	Biomarker	[145]
KLF15	OTGMQMVR	Strong	Altered Expression	[146]
KLHL2	OT1NG8V7	Strong	Biomarker	[147]
LAMP3	OTN0XL3W	Strong	Altered Expression	[148]
LHX1	OT6WI2XS	Strong	Altered Expression	[149]
LIN28B	OTVWP0FN	Strong	Genetic Variation	[150]
LMO1	OTB59SKB	Strong	Genetic Variation	[151]
MAX	OTKZ0YKM	Strong	Biomarker	[23]
MEIS1	OTH9DKAD	Strong	Altered Expression	[152]
MIB1	OT5C404P	Strong	Altered Expression	[153]
MLLT1	OT41UZU5	Strong	Biomarker	[23]
MYH11	OTVNVWY3	Strong	Altered Expression	[15]
NCOA6	OTOMIGTV	Strong	Altered Expression	[154]
NHS	OTKE8QAT	Strong	Genetic Variation	[38]
NIPBL	OTF6OOLU	Strong	Genetic Variation	[155]
NKX2-1	OTCMEJTA	Strong	Biomarker	[124]
NONO	OTN36Q6U	Strong	Biomarker	[23]
NPHS2	OTLCNUII	Strong	Genetic Variation	[77]
NR5A1	OTOULYR4	Strong	Biomarker	[156]
PAF1	OTDDGUBQ	Strong	Genetic Variation	[157]
PAX8	OTRPD9MI	Strong	Altered Expression	[158]
PBX2	OTEBYCAW	Strong	Altered Expression	[152]
PHOX2B	OT3SFR2O	Strong	Genetic Variation	[159]
PLXNA1	OTN0BING	Strong	Biomarker	[125]
PRAM1	OTZN3DWD	Strong	Altered Expression	[160]
PTCH1	OTMG07H5	Strong	Genetic Variation	[161]
QRSL1	OTJDU2UG	Strong	Biomarker	[138]
RBBP7	OTLB56HX	Strong	Altered Expression	[162]
REST	OTLL92LQ	Strong	Biomarker	[163]
RUNX1T1	OT30DED5	Strong	Altered Expression	[15]
SALL4	OTC08PR5	Strong	Biomarker	[124]
SHMT1	OTIINA3J	Strong	Altered Expression	[164]
SIX1	OT70YYWM	Strong	Biomarker	[23]
SLC22A18	OT9C3KR4	Strong	Genetic Variation	[165]
SPI1	OTVCA1D0	Strong	Biomarker	[166]
SRY	OT516T6D	Strong	Genetic Variation	[167]
STIM1	OT8CLQ1W	Strong	Altered Expression	[168]
TCN2	OT41D0L3	Strong	Genetic Variation	[38]
TRIP13	OTFM3TI9	Strong	Genetic Variation	[169]
TTF1	OT4K90WD	Strong	Biomarker	[124]
CIB2	OT9ZJX1I	Definitive	Biomarker	[170]
EMG1	OTFDX7HY	Definitive	Biomarker	[171]
MVP	OTJGHJRB	Definitive	Altered Expression	[172]
NR2C2	OTDZWVOJ	Definitive	Biomarker	[57]
PODXL	OTPNQXF3	Definitive	Biomarker	[173]
PRDM2	OT8L7CGX	Definitive	Biomarker	[174]
RPL10	OTBHOZGC	Definitive	Biomarker	[175]
STIL	OT9799VN	Definitive	Altered Expression	[176]
TBC1D9	OTSSCTB5	Definitive	Biomarker	[177]
TP73	OT0LUO47	Definitive	Altered Expression	[117]
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⏷ Show the Full List of 164 DOT(s)

References

1	Dactinomycin FDA Label
2	Doxorubicin FDA Label
3	Vincristine FDA Label
4	Dietary Turmeric Bisdemethoxycurcumin Suppresses Wilms' Tumor 1 and CD34 Protein Expressions in KG-1a Leukemic Stem Cells.Nutr Cancer. 2019;71(7):1189-1200. doi: 10.1080/01635581.2019.1598565. Epub 2019 Apr 7.
5	Decreased expression of orexin 1 receptor in adult mice testes during alloxan-induced diabetes mellitus perturbs testicular steroidogenesis and glucose homeostasis.Biochem Biophys Res Commun. 2017 Sep 2;490(4):1346-1354. doi: 10.1016/j.bbrc.2017.07.026. Epub 2017 Jul 6.
6	LIN28A gene polymorphisms confer Wilms tumour susceptibility: A four-centre case-control study.J Cell Mol Med. 2019 Oct;23(10):7105-7110. doi: 10.1111/jcmm.14561. Epub 2019 Jul 23.
7	LMO2 gene deletions significantly worsen the prognosis of Wilms' tumor development in patients with WAGR syndrome.Hum Mol Genet. 2019 Oct 1;28(19):3323-3326. doi: 10.1093/hmg/ddz168.
8	Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: AHokkaido Leukemia Net Study.Clin Lymphoma Myeloma Leuk. 2018 Nov;18(11):e469-e479. doi: 10.1016/j.clml.2018.07.291. Epub 2018 Jul 17.
9	WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells. J Clin Endocrinol Metab. 2002 Sep;87(9):4369-77.
10	Induction of antiproliferative connective tissue growth factor expression in Wilms' tumor cells by sphingosine-1-phosphate receptor 2.Mol Cancer Res. 2008 Oct;6(10):1649-56. doi: 10.1158/1541-7786.MCR-07-2048.
11	Global demethylation in loss of imprinting subtype of Wilms tumor.Genes Chromosomes Cancer. 2013 Feb;52(2):174-84. doi: 10.1002/gcc.22017. Epub 2012 Oct 17.
12	Transcriptional regulation of the human thromboxane A2 receptor gene by Wilms' tumor (WT)1 and hypermethylated in cancer (HIC) 1 in prostate and breast cancers.Biochim Biophys Acta. 2014 Jun;1839(6):476-92. doi: 10.1016/j.bbagrm.2014.04.010. Epub 2014 Apr 18.
13	miR-483-5p Targets MKNK1 to Suppress Wilms' Tumor Cell Proliferation and Apoptosis In Vitro and In Vivo.Med Sci Monit. 2019 Feb 24;25:1459-1468. doi: 10.12659/MSM.913005.
14	Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms' Tumor Suppressor Wt1.Cells. 2019 Jan 11;8(1):41. doi: 10.3390/cells8010041.
15	Quantitative assessment of Wilms tumor 1 expression by real-time quantitative polymerase chain reaction in patients with acute myeloblastic leukemia.J Res Med Sci. 2017 Apr 26;22:54. doi: 10.4103/jrms.JRMS_448_16. eCollection 2017.
16	Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients.Oncotarget. 2017 Feb 14;8(7):11173-11186. doi: 10.18632/oncotarget.14491.
17	Quantification of Wilms' tumor 1 mRNA by digital polymerase chain reaction.Int J Hematol. 2018 Feb;107(2):230-234. doi: 10.1007/s12185-017-2336-8. Epub 2017 Oct 9.
18	miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms.Carcinogenesis. 2012 May;33(5):1014-21. doi: 10.1093/carcin/bgs126. Epub 2012 Mar 19.
19	Pitavastatin suppresses hyperglycaemia-induced podocyte injury via bone morphogenetic protein-7 preservation.Clin Exp Pharmacol Physiol. 2017 Mar;44(3):378-385. doi: 10.1111/1440-1681.12716.
20	Consensus for genes to be included on cancer panel tests offered by UK genetics services: guidelines of the UK Cancer Genetics Group.J Med Genet. 2018 Jun;55(6):372-377. doi: 10.1136/jmedgenet-2017-105188. Epub 2018 Apr 16.
21	Beckwith-Wiedemann syndrome: multiple molecular mechanisms.Expert Rev Mol Med. 2006 Jul 17;8(17):1-19. doi: 10.1017/S1462399406000020.
22	Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.Neuro Oncol. 2014 Oct;16(10):1333-40. doi: 10.1093/neuonc/nou052. Epub 2014 Apr 9.
23	A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.Nat Genet. 2017 Oct;49(10):1487-1494. doi: 10.1038/ng.3940. Epub 2017 Aug 21.
24	Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells.Blood. 1998 Apr 15;91(8):2969-76.
25	Wilms tumor, pleuropulmonary blastoma, and DICER1: case report and literature review.World J Surg Oncol. 2018 Aug 10;16(1):164. doi: 10.1186/s12957-018-1469-4.
26	Association of E2F3 expression with clinicopathological features of Wilms' tumors.J Pediatr Surg. 2013 Nov;48(11):2187-93. doi: 10.1016/j.jpedsurg.2013.05.014.
27	Towards an understanding of kidney diseases associated with WT1 mutations.Kidney Int. 2015 Oct;88(4):684-90. doi: 10.1038/ki.2015.198. Epub 2015 Jul 8.
28	Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice.Oncotarget. 2018 Oct 19;9(82):35313-35326. doi: 10.18632/oncotarget.26238. eCollection 2018 Oct 19.
29	Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target.Oncogene. 2011 Apr 7;30(14):1664-80. doi: 10.1038/onc.2010.549. Epub 2011 Jan 17.
30	Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors. Neoplasia. 2007 Nov;9(11):970-8. doi: 10.1593/neo.07661.
31	A phase I clinical study of a cocktail vaccine of Wilms' tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma.Cancer Immunol Immunother. 2019 Feb;68(2):331-340. doi: 10.1007/s00262-018-2274-1. Epub 2018 Nov 14.
32	Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells.Hum Mol Genet. 2015 Mar 1;24(5):1432-40. doi: 10.1093/hmg/ddu559. Epub 2014 Nov 4.
33	Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors.Int J Mol Med. 2015 Feb;35(2):399-404. doi: 10.3892/ijmm.2014.2015. Epub 2014 Nov 28.
34	The expression of the insulin-like growth factor II, JIP-1 and WT1 genes in porcine nephroblastoma.Anticancer Res. 2009 Dec;29(12):4999-5003.
35	Cancer antigen profiling for malignant pleural mesothelioma immunotherapy: expression and coexpression of mesothelin, cancer antigen 125, and Wilms tumor 1.Oncotarget. 2017 Sep 12;8(44):77872-77882. doi: 10.18632/oncotarget.20845. eCollection 2017 Sep 29.
36	Blastemal NCAM(+)ALDH1(+) Wilms' tumor cancer stem cells correlate with disease progression and poor clinical outcome: A pilot study.Pathol Res Pract. 2019 Aug;215(8):152491. doi: 10.1016/j.prp.2019.152491. Epub 2019 Jun 10.
37	CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.Oncotarget. 2014 Jan 30;5(2):386-402. doi: 10.18632/oncotarget.1566.
38	A genome-wide association study identifies susceptibility loci for Wilms tumor.Nat Genet. 2012 Apr 29;44(6):681-4. doi: 10.1038/ng.2251.
39	Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10984-8. doi: 10.1073/pnas.89.22.10984.
40	A versatile platform technology for recombinant vaccines using non-propagative human parainfluenza virus type 2 vector.Sci Rep. 2019 Sep 9;9(1):12901. doi: 10.1038/s41598-019-49579-y.
41	Overexpression of WT1 and PRAME predicts poor outcomes of patients with myelodysplastic syndromes with thrombocytopenia.Blood Adv. 2019 Nov 12;3(21):3406-3418. doi: 10.1182/bloodadvances.2019000564.
42	Dendritic cells generated from acute myeloid leukemia (AML) blasts maintain the expression of immunogenic leukemia associated antigens.Cancer Immunol Immunother. 2005 Jul;54(7):685-93. doi: 10.1007/s00262-004-0631-8. Epub 2004 Dec 31.
43	Tissue expression of retinoic acid receptor alpha and CRABP2 in metastatic nephroblastomas.Diagn Pathol. 2018 Jan 22;13(1):9. doi: 10.1186/s13000-018-0686-z.
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