Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMA13GD)

Drug Name
Cidofovir Drug Info
Synonyms
CDV; Cidofovirum; Forvade; HPMPC; Vistide; Cidofovir anhydrous; GS 0504; GS 504; GS504; Cidofovir (Vistide); Cidofovir (anhydrous); GS-0504; GS-504; Vistide (TN); Vistide, Cidofovir; [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid; (2S)-3-Hydroxy-2-phosphonylmethoxypropyl-cytosine; (S)-1-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine; (S)-1-[3-hydroxy-2-(phosphonylmethoxy)-propyl]cytosine; (S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl-1-(hydroxymethyl)ethoxy)methyl phosphonic acid; (S)-HPMPC; (s)-[[2-(4-amino-2-oxo-1(2h)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid; ({[(2S)-1-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid; 1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine; 1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]-cytosine dihydrate
Indication
Disease Entry ICD 11 Status REF
Cytomegalovirus infection 1D82 Approved [1]
Cytomegalovirus retinitis 9B72.00 Approved [2]
Therapeutic Class
Anti-HIV Agents
Cross-matching ID
PubChem CID
60613
ChEBI ID
CHEBI:3696
CAS Number
CAS 113852-37-2
TTD Drug ID
DMA13GD
VARIDT Drug ID
DR00066
ACDINA Drug ID
D00946

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Herpes simplex virus DNA polymerase UL30 (HSV UL30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [7]
Aciclovir DMYLOVR Genital herpes 1A94 Approved [3]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [8]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [9]
Valganciclovir DMS2IUH Virus infection 1A24-1D9Z Approved [10]
Penciclovir DMOUMDV Herpes simplex labialis 1F00.01 Approved [11]
Famciclovir DMJHLSD Meniere disease AB31.0 Approved [12]
Valacyclovir Hydrochloride DM5I1CE Herpes simplex virus infection 1F00 Approved [3]
Foscavir DM9KJLZ Cytomegalovirus retinitis 9B72.00 Approved [10]
Netivudine DMTKRY1 Virus infection 1A24-1D9Z Phase 3 [13]
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Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [14]
Methotrexate DM2TEOL Anterior urethra cancer Approved [15]
Folic Acid DMEMBJC Colorectal carcinoma Approved [16]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [17]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [20]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [21]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [22]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [23]
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Drug(s) Transported By Organic anion transporter 1 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [25]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [26]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [27]
Aciclovir DMYLOVR Genital herpes 1A94 Approved [27]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [27]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [28]
Olmesartan medoxomil DMWBHRY High blood pressure BA00 Approved [29]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [30]
FLUORESCEIN DMQTFAO Ocular disease 1F00.1Z Approved [31]
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Drug(s) Transported By Organic anion transporter 3 (SLC22A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [26]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [27]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [33]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [34]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [35]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [36]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [37]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [38]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [39]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [40]
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [33]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [42]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [42]
Cefdinir DMJ7A0H Bacterial infection 1A00-1C4Z Approved [43]
Cefaclor DMJXDGC Bacterial infection 1A00-1C4Z Approved [43]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [44]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [45]
Quercetin DM3NC4M Obesity 5B81 Approved [46]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Paclitaxel DMLB81S Breast carcinoma Approved [51]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [52]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [54]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [55]
Flucytosine DM13VTW Cryptococcal meningitis Approved [56]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [59]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [60]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [61]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [62]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [63]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [64]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [65]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [53]
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Drug(s) Affected By Interleukin-19 (IL19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [67]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [67]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [67]
Arsenic DMTL2Y1 N. A. N. A. Approved [68]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [70]
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Drug(s) Affected By Solute carrier family 12 member 8 (SLC12A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [76]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
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Drug(s) Affected By PDZ and LIM domain protein 1 (PDLIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
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Drug(s) Affected By Golgi integral membrane protein 4 (GOLIM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [85]
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Drug(s) Affected By Agrin (AGRN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [87]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [88]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [89]
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Drug(s) Affected By Podocalyxin (PODXL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Folic Acid DMEMBJC Colorectal carcinoma Approved [93]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
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Drug(s) Affected By Pirin (PIR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [100]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
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Drug(s) Affected By TRAF-type zinc finger domain-containing protein 1 (TRAFD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [103]
Bortezomib DMNO38U Leukemia Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [106]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Selenium DM25CGV N. A. N. A. Approved [110]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [111]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [111]
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Drug(s) Affected By Long-chain fatty acid transport protein 2 (SLC27A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [115]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
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Drug(s) Affected By Rho guanine nucleotide exchange factor 10 (ARHGEF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [118]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
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Drug(s) Affected By Apoptosis regulatory protein Siva (SIVA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Bortezomib DMNO38U Leukemia Approved [121]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
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Drug(s) Affected By Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Haloperidol DM96SE0 Delirium Approved [123]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [124]
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Drug(s) Affected By Insulin-induced gene 1 protein (INSIG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [125]
Fluoxetine DM3PD2C Bipolar depression Approved [126]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [127]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [129]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [128]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
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Drug(s) Affected By D-3-phosphoglycerate dehydrogenase (PHGDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [131]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
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Drug(s) Affected By E3 ubiquitin-protein ligase SIAH2 (SIAH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Estrone DM5T6US Acne vulgaris ED80 Approved [133]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
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Drug(s) Affected By Cochlin (COCH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
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Drug(s) Affected By Protein sprouty homolog 1 (SPRY1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
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Drug(s) Affected By Protein regulator of cytokinesis 1 (PRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [89]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
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Drug(s) Affected By TP53-regulated inhibitor of apoptosis 1 (TRIAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [139]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5'-AMP-activated protein kinase subunit beta-2 (PRKAB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Asparagine--tRNA ligase, cytoplasmic (NARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By PR domain zinc finger protein 1 (PRDM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [148]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ibrutinib DMHZCPO Mantle cell lymphoma 2A85.5 Approved [149]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [153]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribosomal L1 domain-containing protein 1 (RSL1D1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase listerin (LTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [156]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 2B1 (SLCO2B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [115]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Ethanol DMDRQZU Chronic pain MG30 Approved [160]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (GCNT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [161]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [163]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-12 (TSPAN12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Folic Acid DMEMBJC Colorectal carcinoma Approved [165]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-E2 (CCNE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [168]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Quercetin DM3NC4M Obesity 5B81 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [171]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione reductase, mitochondrial (GSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [173]
Ketoprofen DMRKXPT Bursitis Approved [174]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [180]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [182]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ceruloplasmin (CP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [184]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [185]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Ampicillin DMHWE7P Acute epiglottitis Approved [85]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(IV) chain (COL4A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [187]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Paclitaxel DMLB81S Breast carcinoma Approved [189]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metallothionein-2 (MT2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [190]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [193]
Quercetin DM3NC4M Obesity 5B81 Approved [194]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fructose-bisphosphate aldolase A (ALDOA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Etretinate DM2CZFA Keratosis ED56 Approved [197]
Methotrexate DM2TEOL Anterior urethra cancer Approved [198]
Quercetin DM3NC4M Obesity 5B81 Approved [199]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [128]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [200]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [201]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [86]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [202]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [204]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [205]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [206]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [207]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [208]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
Ethacrynic acid DM60QMR Edema MG29 Approved [209]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [210]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [211]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [212]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor AP-2-alpha (TFAP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [213]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [133]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [214]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [215]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [213]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin beta-1 (ITGB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [216]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Methotrexate DM2TEOL Anterior urethra cancer Approved [218]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Fructose DM43AN2 Vomiting MD90 Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [221]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bifunctional glutamate/proline--tRNA ligase (EPRS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amino acid transporter heavy chain SLC3A2 (SLC3A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [223]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [223]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Asparagine synthetase (ASNS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [224]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [224]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [131]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [225]
Fluoxetine DM3PD2C Bipolar depression Approved [224]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 19 (KRT19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [95]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
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Drug(s) Affected By Gamma-enolase (ENO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [228]
Estrone DM5T6US Acne vulgaris ED80 Approved [229]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [230]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [231]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [233]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [234]
Verapamil DMA7PEW Angina pectoris BA40 Approved [235]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [236]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [237]
Selenium DM25CGV N. A. N. A. Approved [238]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [239]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [240]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock 70 kDa protein 1A (HSPA1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [242]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Gefitinib DM15F0X Colon adenocarcinoma Approved [243]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Selenium DM25CGV N. A. N. A. Approved [86]
Etretinate DM2CZFA Keratosis ED56 Approved [197]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein RO60 (RO60)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Selenium DM25CGV N. A. N. A. Approved [86]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoic acid receptor alpha (RARA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [246]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [247]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [248]
Ethanol DMDRQZU Chronic pain MG30 Approved [249]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endoplasmic reticulum chaperone BiP (HSPA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [250]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [251]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [252]
Etretinate DM2CZFA Keratosis ED56 Approved [197]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [253]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [254]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [255]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [256]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [258]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [259]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [260]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [261]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA topoisomerase 1 (TOP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [262]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cation-independent mannose-6-phosphate receptor (IGF2R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [264]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Folic Acid DMEMBJC Colorectal carcinoma Approved [165]
Menthol DMG2KW7 Back pain ME84.Z Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prolyl 4-hydroxylase subunit alpha-1 (P4HA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [267]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fos-related antigen 1 (FOSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [268]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [270]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [271]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fos-related antigen 2 (FOSL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [272]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [273]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [276]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [277]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [278]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [279]
Quercetin DM3NC4M Obesity 5B81 Approved [280]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.2 (H1-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aspartate aminotransferase, cytoplasmic (GOT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [282]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [283]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein SON (SON)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [284]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-3 (ATF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [285]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [193]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [127]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Selenium DM25CGV N. A. N. A. Approved [86]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [286]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [287]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [268]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [288]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 15 (KRT15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [95]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin-A1 (EFNA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [290]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Estrone DM5T6US Acne vulgaris ED80 Approved [133]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iduronate 2-sulfatase (IDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ferrochelatase, mitochondrial (FECH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Selenium DM25CGV N. A. N. A. Approved [86]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [291]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [292]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [292]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diacylglycerol kinase alpha (DGKA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [226]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Gefitinib DM15F0X Colon adenocarcinoma Approved [294]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [295]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [296]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [297]
Quercetin DM3NC4M Obesity 5B81 Approved [298]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [299]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [300]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thromboxane-A synthase (TBXAS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Quinolones DM5GVHU Bacterial infection 1A00-1C4Z Approved [301]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [302]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bromodomain-containing protein 2 (BRD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [303]
Methotrexate DM2TEOL Anterior urethra cancer Approved [304]
Epinephrine DM3KJBC Acute asthma CA23 Approved [305]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [306]
Fructose DM43AN2 Vomiting MD90 Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [186]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Threonine--tRNA ligase 1, cytoplasmic (TARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
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Drug(s) Affected By Adenylate kinase 4, mitochondrial (AK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [307]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Folic Acid DMEMBJC Colorectal carcinoma Approved [93]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
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Drug(s) Affected By ETS domain-containing protein Elk-4 (ELK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [308]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Folic Acid DMEMBJC Colorectal carcinoma Approved [165]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
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Drug(s) Affected By Tyrosine-protein kinase receptor UFO (AXL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [297]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [297]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [309]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [310]
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Drug(s) Affected By High affinity cationic amino acid transporter 1 (SLC7A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent taurine transporter (SLC6A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [312]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [314]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [315]
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Drug(s) Affected By 14-3-3 protein sigma (SFN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Gefitinib DM15F0X Colon adenocarcinoma Approved [294]
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [297]
Quercetin DM3NC4M Obesity 5B81 Approved [317]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [179]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [297]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [318]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [319]
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Drug(s) Affected By Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Benzatropine DMF7EXL Parkinsonian disorder Approved [123]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Long-chain-fatty-acid--CoA ligase 1 (ACSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [320]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [321]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [108]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [251]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [253]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [322]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [323]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [324]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [325]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [326]
Quercetin DM3NC4M Obesity 5B81 Approved [327]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [328]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [329]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [330]
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Drug(s) Affected By Serpin B5 (SERPINB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [331]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [332]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [333]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [334]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [192]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [335]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [336]
Quercetin DM3NC4M Obesity 5B81 Approved [337]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [338]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [339]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [340]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [341]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [342]
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Drug(s) Affected By Transaldolase (TALDO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [343]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [171]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [344]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [216]
Gefitinib DM15F0X Colon adenocarcinoma Approved [345]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [346]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Etretinate DM2CZFA Keratosis ED56 Approved [347]
Prednisone DM2HG4X Acute asthma CA23 Approved [348]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [349]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
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Drug(s) Affected By Glycine--tRNA ligase (GARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [294]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [350]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [351]
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Drug(s) Affected By Isoleucine--tRNA ligase, cytoplasmic (IARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [145]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 9 (TNFSF9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [297]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [297]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [352]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neutral amino acid transporter A (SLC1A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [181]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
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Drug(s) Affected By Nicotinamide phosphoribosyltransferase (NAMPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [353]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [354]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family G member 1 (ABCG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [355]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [179]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [356]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
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Drug(s) Affected By Retinaldehyde dehydrogenase 3 (ALDH1A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [174]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [356]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent glycine transporter 1 (SLC6A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [274]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [115]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
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Drug(s) Affected By Glutamate--cysteine ligase catalytic subunit (GCLC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [237]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [358]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [177]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [359]
Quercetin DM3NC4M Obesity 5B81 Approved [360]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [361]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [362]
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Drug(s) Affected By Glutamate--cysteine ligase regulatory subunit (GCLM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [363]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [318]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alanine--tRNA ligase, cytoplasmic (AARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [365]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [366]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
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Drug(s) Affected By Cysteine--tRNA ligase, cytoplasmic (CARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [223]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
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Drug(s) Affected By Serine--tRNA ligase, cytoplasmic (SARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Haloperidol DM96SE0 Delirium Approved [123]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Benzatropine DMF7EXL Parkinsonian disorder Approved [123]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [368]
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Drug(s) Affected By Max-interacting protein 1 (MXI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [285]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [369]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [370]
Diazepam DM08E9O Alcohol withdrawal Approved [371]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [372]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [370]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [373]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
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Drug(s) Affected By Dipeptidyl peptidase 1 (CTSC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Folic Acid DMEMBJC Colorectal carcinoma Approved [93]
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Drug(s) Affected By Ataxin-1 (ATXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Selenium DM25CGV N. A. N. A. Approved [86]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [156]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
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Drug(s) Affected By Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Haloperidol DM96SE0 Delirium Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
Bortezomib DMNO38U Leukemia Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
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Drug(s) Affected By Serine/threonine-protein kinase SIK1 (SIK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [310]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [374]
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Drug(s) Affected By Ribose-phosphate pyrophosphokinase 1 (PRPS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [375]
Arsenic DMTL2Y1 N. A. N. A. Approved [376]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [378]
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Drug(s) Affected By Rho-related GTP-binding protein RhoE (RND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [379]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
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Drug(s) Affected By Protein BTG2 (BTG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [380]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [381]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [148]
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Drug(s) Affected By E3 ubiquitin-protein ligase Mdm2 (MDM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Flucytosine DM13VTW Cryptococcal meningitis Approved [56]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [382]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [383]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [49]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Amifostine DM5FL14 Mucositis CA00 Approved [384]
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Drug(s) Affected By Runt-related transcription factor 1 (RUNX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Cotinine DMCEZ1B Insecticide N.A. Approved [385]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [386]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large neutral amino acids transporter small subunit 1 (SLC7A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [133]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [318]
Estrone DM5T6US Acne vulgaris ED80 Approved [133]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 1,4-alpha-glucan-branching enzyme (GBE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [307]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [387]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [65]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Verapamil DMA7PEW Angina pectoris BA40 Approved [388]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [186]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [389]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [346]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Meloxicam DM2AR7L Arthritis FA20 Approved [390]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [349]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 94 (TMEM94)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [391]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [392]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [284]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [284]
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Drug(s) Affected By Zinc finger protein Rlf (RLF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase G (PPIG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-31 (RAB31)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [303]
Methotrexate DM2TEOL Anterior urethra cancer Approved [393]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [394]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [395]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [396]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [397]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Runt-related transcription factor 2 (RUNX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [398]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [399]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [400]
Quercetin DM3NC4M Obesity 5B81 Approved [401]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [263]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [402]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [403]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch-like ECH-associated protein 1 (KEAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [404]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [128]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [405]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [406]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [407]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
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Drug(s) Affected By Dihydropyrimidinase-related protein 3 (DPYSL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [264]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
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Drug(s) Affected By Src substrate cortactin (CTTN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [408]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
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Drug(s) Affected By Enhancer of filamentation 1 (NEDD9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [95]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
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Drug(s) Affected By Protein disulfide-isomerase A5 (PDIA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
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Drug(s) Affected By Transmembrane glycoprotein NMB (GPNMB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [409]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
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Drug(s) Affected By Condensin complex subunit 1 (NCAPD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [410]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
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Drug(s) Affected By Probable E3 ubiquitin-protein ligase HERC3 (HERC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [201]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [411]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [412]
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Drug(s) Affected By Plectin (PLEC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [413]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [312]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [414]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disks large-associated protein 5 (DLGAP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein RP/EB family member 2 (MAPRE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [281]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [281]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [284]
Okadaic acid DM47CO1 Discovery agent N.A. Investigative [415]
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Drug(s) Affected By Neutral amino acid transporter B(0) (SLC1A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [105]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [105]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [416]
Verapamil DMA7PEW Angina pectoris BA40 Approved [235]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Selenium DM25CGV N. A. N. A. Approved [86]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [417]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [278]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [279]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [418]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Fluoxetine DM3PD2C Bipolar depression Approved [223]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Estrone DM5T6US Acne vulgaris ED80 Approved [133]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuronal regeneration-related protein (NREP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Folic Acid DMEMBJC Colorectal carcinoma Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By kinase isozyme 4, mitochondrial (PDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [134]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [419]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [420]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [421]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [422]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [423]
Prednisone DM2HG4X Acute asthma CA23 Approved [424]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [424]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [425]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [426]
Epinephrine DM3KJBC Acute asthma CA23 Approved [427]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Fluoxetine DM3PD2C Bipolar depression Approved [126]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [428]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [205]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [429]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [430]
Estrone DM5T6US Acne vulgaris ED80 Approved [431]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [432]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [433]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [434]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [435]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [234]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 5 (DUSP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [436]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Laminin subunit alpha-3 (LAMA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [95]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [410]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ethanol DMDRQZU Chronic pain MG30 Approved [437]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [181]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D53 (TPD52L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Atos homolog protein A (ATOSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [439]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycerol-3-phosphate acyltransferase 3 (GPAT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Quinone oxidoreductase PIG3 (TP53I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [303]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [317]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [440]
Amifostine DM5FL14 Mucositis CA00 Approved [384]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [441]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FRAS1-related extracellular matrix protein 2 (FREM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ethanol DMDRQZU Chronic pain MG30 Approved [442]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [443]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ALS2 C-terminal-like protein (ALS2CL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endogenous Bornavirus-like nucleoprotein 2 (EBLN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [444]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [81]
Milchsaure DM462BT Pruritus EC90 Investigative [445]
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Drug(s) Affected By ATPase family AAA domain-containing protein 2 (ATAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [409]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [157]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribosomal protein eS27-like (RPS27L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [351]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arginine/serine-rich coiled-coil protein 2 (RSRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [446]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BEN domain-containing protein 5 (BEND5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [447]
Arsenic DMTL2Y1 N. A. N. A. Approved [68]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial enolase superfamily member 1 (ENOSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [397]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [448]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase TAO1 (TAOK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [156]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [157]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [449]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [450]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [450]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable helicase senataxin (SETX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Clozapine DMFC71L Schizophrenia 6A20 Approved [123]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [451]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [284]
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Drug(s) Affected By Protein mono-ADP-ribosyltransferase TIPARP (TIPARP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein LYRIC (MTDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [138]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [444]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Liprin-beta-1 (PPFIBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [156]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Extracellular sulfatase Sulf-2 (SULF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Patatin-like phospholipase domain-containing protein 6 (PNPLA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [452]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [453]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable ATP-dependent RNA helicase DHX37 (DHX37)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [454]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [455]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromal membrane-associated protein 1 (SMAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Ethanol DMDRQZU Chronic pain MG30 Approved [456]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [138]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [439]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein O-mannosyl-transferase TMTC2 (TMTC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [457]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CAP-Gly domain-containing linker protein 4 (CLIP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Bortezomib DMNO38U Leukemia Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ninein (NIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [458]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Tubocurarine DMBZIVP Anaesthesia 9A78.6 Approved [449]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ceramide synthase 5 (CERS5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [459]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 22 (FBXO22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Folic Acid DMEMBJC Colorectal carcinoma Approved [165]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [366]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By (Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box only protein 30 (FBXO30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pantothenate kinase 1 (PANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [127]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SH3 domain and tetratricopeptide repeat-containing protein 1 (SH3TC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C4orf3 (C4ORF3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Bortezomib DMNO38U Leukemia Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paraspeckle component 1 (PSPC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [365]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [460]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [461]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone acetyltransferase KAT6B (KAT6B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Bortezomib DMNO38U Leukemia Approved [104]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [462]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase rififylin (RFFL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [351]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-binding protein 2 (DDB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [463]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sortilin-related receptor (SORL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho-related GTP-binding protein Rho6 (RND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [453]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [464]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable ATP-dependent RNA helicase DDX17 (DDX17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Selenium DM25CGV N. A. N. A. Approved [86]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [465]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [148]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding protein Rit1 (RIT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [103]
Bortezomib DMNO38U Leukemia Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ninjurin-1 (NINJ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [397]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [397]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By KICSTOR complex protein ITFG2 (ITFG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein TMEPAI (PMEPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [466]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM162A (FAM162A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [181]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein p53-inducible nuclear protein 1 (TP53INP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [467]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 45B (TMEM45B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [147]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [453]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [76]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxymethylenebutenolidase homolog (CMBL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aurora kinase B (AURKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [344]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [168]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [468]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [409]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM89A (FAM89A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [79]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [469]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ERO1-like protein alpha (ERO1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [470]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein LRATD2 (LRATD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [310]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Ethanol DMDRQZU Chronic pain MG30 Approved [249]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM210B, mitochondrial (FAM210B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E1A-binding protein p400 (EP400)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [284]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [157]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [451]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-modifying factor (BMF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [312]
Panobinostat DM58WKG Chronic graft versus host disease Approved [285]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [362]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [471]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [248]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [127]
Menthol DMG2KW7 Back pain ME84.Z Approved [265]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM210A (FAM210A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [444]
Milchsaure DM462BT Pruritus EC90 Investigative [445]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [472]
1,6-hexamethylene diisocyanate DMLB3RT Discovery agent N.A. Investigative [473]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Bcl-2-binding component 3, isoforms 3/4 (BBC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [303]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [393]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [474]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [219]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [396]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [475]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [476]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [471]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [454]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [477]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Spermatid perinuclear RNA-binding protein (STRBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [478]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [478]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 3 subunit C (EIF3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [350]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [462]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell surface A33 antigen (GPA33)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [391]
Drug(s) Affected By Growth/differentiation factor 15 (GDF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [479]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [95]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [480]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [481]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cancer-related nucleoside-triphosphatase (NTPCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxidoreductase HTATIP2 (HTATIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [97]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [482]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [482]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G-protein coupled receptor 87 (GPR87)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [227]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [483]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiopoietin-related protein 4 (ANGPTL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [174]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [484]
Ethacrynic acid DM60QMR Edema MG29 Approved [485]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [223]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Fructose DM43AN2 Vomiting MD90 Approved [486]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
D-glucose DMMG2TO Discovery agent N.A. Investigative [486]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coiled-coil domain-containing protein 90B, mitochondrial (CCDC90B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [448]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [487]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [488]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [154]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [87]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [369]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-directed RNA polymerase III subunit RPC6 (POLR3F)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [451]
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Drug(s) Affected By Iron-sulfur cluster assembly enzyme ISCU (ISCU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [334]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [489]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [487]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [138]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK3 (PLK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [453]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
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Drug(s) Affected By Polyprenol reductase (SRD5A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
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Drug(s) Affected By E3 ubiquitin ligase RNF121 (RNF121)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [311]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [490]
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Drug(s) Affected By Ankyrin repeat family A protein 2 (ANKRA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
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Drug(s) Affected By p53-induced death domain-containing protein 1 (PIDD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [6]
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Drug(s) Affected By Stromal cell-derived factor 2-like protein 1 (SDF2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [96]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [491]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [453]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
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Drug(s) Affected By ATP-binding cassette sub-family B member 6 (ABCB6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [115]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Paclitaxel DMLB81S Breast carcinoma Approved [492]
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Drug(s) Affected By ABC-type oligopeptide transporter ABCB9 (ABCB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [114]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [493]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [494]
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Drug(s) Affected By Suppressor of SWI4 1 homolog (PPAN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
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Drug(s) Affected By Fructose-2,6-bisphosphatase TIGAR (TIGAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [241]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
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Drug(s) Affected By Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [462]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
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Drug(s) Affected By Dual specificity protein phosphatase 22 (DUSP22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [366]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [430]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [495]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [444]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [76]
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Drug(s) Affected By PAK4-inhibitor INKA2 (INKA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [469]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [366]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [496]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [497]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3-oxoacyl- synthase, mitochondrial (OXSM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [469]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [448]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [138]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [444]
Milchsaure DM462BT Pruritus EC90 Investigative [445]
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Drug(s) Affected By DNA damage-inducible transcript 4 protein (DDIT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [125]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [498]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
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Drug(s) Affected By Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [131]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [131]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Indomethacin DMSC4A7 Bursitis Approved [499]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [131]
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Drug(s) Affected By LIM and cysteine-rich domains protein 1 (LMCD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [124]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [188]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Signal-induced proliferation-associated 1-like protein 2 (SIPA1L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [500]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [368]
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Drug(s) Affected By Leucine--tRNA ligase, cytoplasmic (LARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [157]
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Drug(s) Affected By Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [81]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [103]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
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Drug(s) Affected By DnaJ homolog subfamily B member 9 (DNAJB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [268]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [153]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [491]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [367]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [124]
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Drug(s) Affected By Mitochondrial fission process protein 1 (MTFP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
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Drug(s) Affected By SERTA domain-containing protein 1 (SERTAD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [90]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
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Drug(s) Affected By GTP:AMP phosphotransferase AK3, mitochondrial (AK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [78]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [103]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
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Drug(s) Affected By Tubulointerstitial nephritis antigen (TINAG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [67]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [469]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [443]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [155]
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Drug(s) Affected By Oxidative stress-induced growth inhibitor 1 (OSGIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [6]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
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Drug(s) Affected By Two pore channel protein 1 (TPCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [6]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [166]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [285]
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Drug(s) Affected By Ras-related protein Rab-26 (RAB26)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [132]
Testosterone DM7HUNW Hot flushes GA30 Approved [144]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [369]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [438]
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Drug(s) Affected By Heme transporter FLVCR2 (FLVCR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [84]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysine-specific demethylase 3A (KDM3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [501]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA polymerase II subunit A C-terminal domain phosphatase (CTDP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Testosterone enanthate DMB6871 N. A. N. A. Approved [83]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [6]
Arsenic DMTL2Y1 N. A. N. A. Approved [119]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [120]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pleckstrin homology-like domain family A member 3 (PHLDA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [98]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [155]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [6]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoserine aminotransferase (PSAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [409]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [140]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [6]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sestrin-1 (SESN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [116]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [172]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
Testosterone DM7HUNW Hot flushes GA30 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [92]
Leflunomide DMR8ONJ Arthritis FA20 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [387]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [502]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [503]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [504]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [174]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [191]
Verapamil DMA7PEW Angina pectoris BA40 Approved [388]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [505]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [506]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [507]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatitis A virus cellular receptor 1 (HAVCR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [508]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [88]
Gentamicin DMKINJO Bacteremia 1A73 Approved [509]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [510]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [511]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [512]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [377]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By UMP-CMP kinase (CMPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Urethane DM7NSI0 N. A. N. A. Phase 4 [146]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [69]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [497]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Pre-mRNA-processing factor 19 (PRPF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [80]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [77]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [513]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [514]
⏷ Show the Full List of 6 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30) TTIU7X1 DPOL_HHV11 Modulator [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [4]
Organic anion transporter 1 (SLC22A6) DTQ23VB S22A6_HUMAN Substrate [5]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
(E3-independent) E2 ubiquitin-conjugating enzyme OTHGS2VA UBE2O_HUMAN Gene/Protein Processing [6]
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4) OTQK3M9X ABHD4_HUMAN Gene/Protein Processing [6]
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Gene/Protein Processing [6]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [6]
3'-5' RNA helicase YTHDC2 OTYDYKDY YTDC2_HUMAN Gene/Protein Processing [6]
3-oxoacyl- synthase, mitochondrial (OXSM) OTMDWHOM OXSM_HUMAN Gene/Protein Processing [6]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) OTLVN68B AAKB2_HUMAN Gene/Protein Processing [6]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) OTQYEXL2 F264_HUMAN Gene/Protein Processing [6]
ABC-type oligopeptide transporter ABCB9 (ABCB9) OTSOBOL5 ABCB9_HUMAN Gene/Protein Processing [6]
Adenylate kinase 4, mitochondrial (AK4) OTA0T02Q KAD4_HUMAN Gene/Protein Processing [6]

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