Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMFC71L)

Drug Name
Clozapine Drug Info
Synonyms
Asaleptin; CLOZARIL; Clorazil; Clozapin; Clozapina; Clozapinum; Fazaclo; Iprox; Leponex; Lepotex; Fazaclo ODT; C 6305; HF1854; Clopine (TN); Clozapina [INN-Spanish]; Clozapine(tautomer); Clozapinum [INN-Latin]; Clozaril (TN); Denzapine (TN); Fazaclo (TN); Froidir (TN); HF-1854; KS-1166; Klozapol (TN); LEX-123; LX 100-129; Leponex (TN); W-801; Zaponex (TN); Clozapine [USAN:INN:BAN]; Clozapine (JAN/USP/INN); 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepine; 8-Chloro-11-(4-methyl)-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo (b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine; 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine; 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Indication
Disease Entry ICD 11 Status REF
Schizophrenia 6A20 Approved [1]
Treatment-refractory schizophrenia Investigative [2]
Therapeutic Class
Antipsychotic Agents
Cross-matching ID
PubChem CID
135398737
ChEBI ID
CHEMBL42
CAS Number
CAS 5786-21-0
TTD Drug ID
DMFC71L
VARIDT Drug ID
DR00474
INTEDE Drug ID
DR0363
ACDINA Drug ID
D00145

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Dopamine D4 receptor (D4R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenyltoloxamine DMKAEQW Allergy 4A80-4A85 Approved [15]
CM-2395 DMASPWR Schizophrenia 6A20 Phase 3 [16]
RP5063 DMKUE8O Schizophrenia 6A20 Phase 2 [17]
L-745,870 DMTGR25 Psychotic disorder 6A20-6A25 Phase 2 [18]
NGD 94-1 DMM1Y8F Schizophrenia 6A20 Phase 1 [19]
ABT-724 DMDQVY4 Erectile dysfunction HA01.1 Discontinued in Phase 2 [20]
Lu-35138 DMQ7A35 Psychotic disorder 6A20-6A25 Discontinued in Phase 2 [21]
NGD-94-4 DMZ9WLO Schizophrenia 6A20 Discontinued in Phase 1 [22]
PD-165167 DMD0GB4 Schizophrenia 6A20 Preclinical [19]
SPI-376 DMC1WAJ Schizophrenia 6A20 Preclinical [19]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [23]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [24]
Methotrexate DM2TEOL Anterior urethra cancer Approved [25]
Folic Acid DMEMBJC Colorectal carcinoma Approved [26]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [25]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [25]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [27]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [25]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [28]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [29]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [30]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [31]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [35]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [31]
Verapamil DMA7PEW Angina pectoris BA40 Approved [38]
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Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [40]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [41]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [42]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [43]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [45]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [47]
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Drug(s) Metabolized By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [48]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [50]
Metronidazole DMTIVEN Abscess Approved [51]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [52]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [53]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [48]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [54]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [55]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [56]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [57]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [58]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [59]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [60]
Propranolol DM79NTF Angina pectoris BA40 Approved [61]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [62]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [62]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Verapamil DMA7PEW Angina pectoris BA40 Approved [63]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [64]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [65]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [62]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [66]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [52]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [67]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [68]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [69]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [48]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [70]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Verapamil DMA7PEW Angina pectoris BA40 Approved [71]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [72]
Estrone DM5T6US Acne vulgaris ED80 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [75]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [67]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [76]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [77]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [48]
Verapamil DMA7PEW Angina pectoris BA40 Approved [78]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [79]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [74]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [80]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [52]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [81]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [82]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [83]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [84]
Cepharanthine DM9Y5JB N. A. N. A. Approved [85]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [86]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [87]
Trifluoperazine DMKBYWI Anxiety Approved [88]
Olanzapine DMPFN6Y Bipolar depression Approved [89]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [84]
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Drug(s) Affected By D(4) dopamine receptor (DRD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [90]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [92]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Methamphetamine DMPM4SK Anxiety Approved [95]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [96]
Droperidol DM0DXA8 Nausea MD90 Approved [97]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [97]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [97]
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Drug(s) Affected By D(3) dopamine receptor (DRD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [98]
Risperidone DMN6DXL Bipolar I disorder Approved [99]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
Methamphetamine DMPM4SK Anxiety Approved [101]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [102]
Droperidol DM0DXA8 Nausea MD90 Approved [97]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [97]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [97]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [97]
Trifluoperazine DMKBYWI Anxiety Approved [97]
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Drug(s) Affected By Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (GNB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [104]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [105]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [107]
Sibutramine DMFJTDI Obesity 5B81 Approved [108]
Almogran DM7I64Z Migraine 8A80 Approved [109]
Eletriptan DMW649X Migraine 8A80 Approved [109]
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Drug(s) Affected By D(2) dopamine receptor (DRD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Droperidol DM0DXA8 Nausea MD90 Approved [97]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [97]
Zuclopenthixol DMKYD5N Schizophrenia 6A20 Approved [97]
Meglitinides DM1OFHN Type-2 diabetes 5A11 Approved [110]
Sulpiride DMF54ZG Schizophrenia 6A20 Approved [111]
Risperidone DMN6DXL Bipolar I disorder Approved [112]
Olanzapine DMPFN6Y Bipolar depression Approved [113]
Methamphetamine DMPM4SK Anxiety Approved [114]
Bromocriptine DMVE3TK Acromegaly 5A60.0 Approved [115]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [116]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [119]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [120]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [122]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [119]
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Drug(s) Affected By Alpha-1-antichymotrypsin (SERPINA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [120]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [124]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [118]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [126]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [127]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [120]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [129]
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Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [120]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [130]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [119]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [118]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
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Drug(s) Affected By Acid ceramidase (ASAH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [132]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [119]
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Drug(s) Affected By Nuclear receptor subfamily 0 group B member 2 (NR0B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [135]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [138]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [119]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
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Drug(s) Affected By Lysophospholipase D GDPD3 (GDPD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [120]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [119]
Fluoxetine DM3PD2C Bipolar depression Approved [119]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [118]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [140]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Haloperidol DM96SE0 Delirium Approved [119]
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Drug(s) Affected By Fibronectin type III domain-containing protein 4 (FNDC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [119]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [118]
Haloperidol DM96SE0 Delirium Approved [119]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [118]
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Drug(s) Affected By Protein DEPP1 (DEPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [119]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [143]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [118]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [119]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [119]
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Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [138]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [145]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [146]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [124]
Fluoxetine DM3PD2C Bipolar depression Approved [145]
Fructose DM43AN2 Vomiting MD90 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [145]
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Drug(s) Affected By Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [145]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [151]
Fluoxetine DM3PD2C Bipolar depression Approved [145]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
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Drug(s) Affected By Lathosterol oxidase (SC5D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Fluoxetine DM3PD2C Bipolar depression Approved [153]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [156]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Haloperidol DM96SE0 Delirium Approved [156]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
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Drug(s) Affected By Farnesyl pyrophosphate synthase (FDPS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [159]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sterol regulatory element-binding protein 2 (SREBF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [164]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [165]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [166]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [168]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-CoA acetyltransferase, cytosolic (ACAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [174]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 7-dehydrocholesterol reductase (DHCR7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [176]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [153]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [177]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By AP-1 complex subunit sigma-1A (AP1S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [118]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Fluoxetine DM3PD2C Bipolar depression Approved [118]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [182]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [120]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein CXorf49 (CXORF49)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Drug(s) Affected By Cytosolic acyl coenzyme A thioester hydrolase (ACOT7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [184]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Bortezomib DMNO38U Leukemia Approved [186]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By AP-3 complex subunit beta-1 (AP3B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [189]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [190]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Galectin-8 (LGALS8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [92]
Bortezomib DMNO38U Leukemia Approved [186]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome non-ATPase regulatory subunit 14 (PSMD14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [194]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [193]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [193]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syntenin-1 (SDCBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [196]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [196]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [198]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Importin subunit alpha-3 (KPNA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydropyrimidinase-related protein 4 (DPYSL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [201]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [201]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [201]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [202]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Cytoplasmic dynein 1 light intermediate chain 2 (DYNC1LI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [206]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [207]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RNF13 (RNF13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [194]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [210]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Calumenin (CALU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [182]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [211]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin heavy chain isoform 5C (KIF5C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [179]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [212]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [213]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [215]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [217]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [218]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-3 (TSPAN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [219]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 5B (EIF5B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [226]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [148]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 3 subunit J (EIF3J)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutaredoxin-3 (GLRX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [186]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pre-mRNA-processing factor 6 (PRPF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Bortezomib DMNO38U Leukemia Approved [186]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [230]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein transport protein Sec31A (SEC31A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 15 (TNFSF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [235]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Menthol DMG2KW7 Back pain ME84.Z Approved [236]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Arsenic DMTL2Y1 N. A. N. A. Approved [237]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [239]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [240]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [240]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [241]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [239]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [240]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [242]
Gefitinib DM15F0X Colon adenocarcinoma Approved [239]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [243]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuroendocrine secretory protein 55 (GNAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [245]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [246]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [247]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [248]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenylate kinase isoenzyme 1 (AK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [97]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [97]
Anastrozole DMNP60F Breast cancer 2C60-2C65 Approved [97]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Argininosuccinate synthase (ASS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [196]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [249]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [196]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-2 receptor subunit alpha (IL2RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [250]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [251]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [252]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [253]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [254]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [255]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [256]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-reactive protein (CRP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [97]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [257]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [258]
Quercetin DM3NC4M Obesity 5B81 Approved [259]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Acalabrutinib DM7GCVW leukaemia 2A60-2B33 Approved [260]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [261]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [262]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [263]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [97]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [264]
Diazepam DM08E9O Alcohol withdrawal Approved [265]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [266]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [267]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [268]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [269]
Methotrexate DM2TEOL Anterior urethra cancer Approved [270]
Quercetin DM3NC4M Obesity 5B81 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A1 (ANXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [272]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [273]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [140]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [275]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [276]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [277]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [278]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fructose-bisphosphate aldolase B (ALDOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [130]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [241]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amyloid-beta precursor protein (APP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Selenium DM25CGV N. A. N. A. Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [146]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [281]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [282]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [283]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [284]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [285]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin light chain 1/3, skeletal muscle isoform (MYL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Norepinephrine DMOUC09 Alopecia ED70 Approved [286]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [238]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [288]
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Drug(s) Affected By Prothymosin alpha (PTMA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [289]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [290]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [275]
Haloperidol DM96SE0 Delirium Approved [10]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [291]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A6 (ANXA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [292]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amino acid transporter heavy chain SLC3A2 (SLC3A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [294]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [295]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [296]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [296]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CD63 antigen (CD63)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [298]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [299]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [300]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrilysin (MMP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [301]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [122]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [302]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [212]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [303]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [304]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromelysin-2 (MMP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Methotrexate DM2TEOL Anterior urethra cancer Approved [305]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [306]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [305]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Haloperidol DM96SE0 Delirium Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth-regulated alpha protein (CXCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [307]
Selenium DM25CGV N. A. N. A. Approved [308]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [124]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [305]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydropteridine reductase (QDPR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [310]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [311]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [273]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [312]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [246]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [313]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [314]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [315]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [316]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [317]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [143]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [318]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [319]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [320]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [318]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [146]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [312]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin-3 (MYH3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histidine--tRNA ligase, cytoplasmic (HARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ADP/ATP translocase 3 (SLC25A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [322]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [188]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleoprotein TPR (TPR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [324]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HLA class I histocompatibility antigen, alpha chain E (HLA-E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [325]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [325]
Selenium DM25CGV N. A. N. A. Approved [164]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [325]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [325]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [325]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plastin-3 (PLS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [326]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [238]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Arsenic DMTL2Y1 N. A. N. A. Approved [327]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-enolase (ENO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [289]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [328]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [329]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [330]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon gamma receptor 1 (IFNGR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [331]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [332]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [333]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ezrin (EZR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [334]
Haloperidol DM96SE0 Delirium Approved [10]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By V-type proton ATPase subunit B, kidney isoform (ATP6V1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [273]
Haloperidol DM96SE0 Delirium Approved [10]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Histone H1.2 (H1-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome regulatory subunit 6A (PSMC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [230]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By V-type proton ATPase subunit B, brain isoform (ATP6V1B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [338]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [190]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [288]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Trifunctional purine biosynthetic protein adenosine-3 (GART)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [339]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 1 (CCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [340]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [341]
Arsenic DMTL2Y1 N. A. N. A. Approved [342]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [238]
ACYLINE DM9GRTK Prostate cancer 2C82.0 Phase 2 [343]
ANW-32821 DMMJOZD N. A. N. A. Phase 2 [344]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [346]
Nickel chloride DMI12Y8 Discovery agent N.A. Investigative [347]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Splicing factor, proline- and glutamine-rich (SFPQ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [348]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [349]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein uS3 (RPS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [248]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase JAK1 (JAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [350]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [351]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Replication protein A 70 kDa DNA-binding subunit (RPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [352]
Gefitinib DM15F0X Colon adenocarcinoma Approved [353]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [354]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calnexin (CANX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [355]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [356]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Elongation factor 1-delta (EEF1D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [358]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein disulfide-isomerase A3 (PDIA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [359]
Etretinate DM2CZFA Keratosis ED56 Approved [360]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lipocalin-1 (LCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [362]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [328]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [363]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
1-anilinonaphthalene-8-sulfonic acid DMNGY0E N. A. N. A. Investigative [362]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Stress-induced-phosphoprotein 1 (STIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [364]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [365]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Tubocurarine DMBZIVP Anaesthesia 9A78.6 Approved [207]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [207]
Paclitaxel DMLB81S Breast carcinoma Approved [366]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [297]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cleavage stimulation factor subunit 2 (CSTF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [367]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [367]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [247]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 7 (HTR7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Cyproheptadine DM92AH3 Allergic rhinitis CA08.0 Approved [368]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [202]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [369]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [370]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
SL65.0472 DMU5RKC Cardiovascular disease BA00-BE2Z Discontinued in Phase 2 [90]
SB-269970 DM8WTGA Sleep-wake disorder 7A00-7B2Z Terminated [368]
ICI-169369 DMQ0IOF Anxiety disorder 6B00-6B0Z Terminated [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [217]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [358]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [363]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stress-70 protein, mitochondrial (HSPA9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [371]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [372]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [322]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [373]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Flap endonuclease 1 (FEN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [117]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [374]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [339]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [375]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Malate dehydrogenase, cytoplasmic (MDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [376]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [348]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Replication factor C subunit 5 (RFC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [352]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [306]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [375]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [377]
Paclitaxel DMLB81S Breast carcinoma Approved [366]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Bortezomib DMNO38U Leukemia Approved [186]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [148]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-48 DMPIM9L N. A. N. A. Patented [379]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [197]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-alpha-acetyltransferase 10 (NAA10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
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Drug(s) Affected By Lamina-associated polypeptide 2, isoform alpha (TMPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [374]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [380]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
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Drug(s) Affected By Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [381]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [217]
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Drug(s) Affected By C-X-C motif chemokine 5 (CXCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [352]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [307]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [304]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [382]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [383]
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Drug(s) Affected By Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [384]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
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Drug(s) Affected By Vesicle-fusing ATPase (NSF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [385]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
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Drug(s) Affected By Large ribosomal subunit protein uL18 (RPL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
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Drug(s) Affected By Microtubule-associated protein 1B (MAP1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [364]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [140]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Folic Acid DMEMBJC Colorectal carcinoma Approved [386]
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Drug(s) Affected By Phosphatidylinositol transfer protein beta isoform (PITPNB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [387]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [388]
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Drug(s) Affected By Alanine--tRNA ligase, cytoplasmic (AARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine--tRNA ligase, cytoplasmic (CARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [296]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [389]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [296]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine--tRNA ligase, cytoplasmic (SARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Haloperidol DM96SE0 Delirium Approved [10]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [297]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [390]
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Drug(s) Affected By Acyl-coenzyme A thioesterase 2, mitochondrial (ACOT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [391]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [226]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [392]
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Drug(s) Affected By Transmembrane emp24 domain-containing protein 10 (TMED10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [393]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [394]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [277]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [395]
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Drug(s) Affected By 5-hydroxytryptamine receptor 6 (HTR6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Olanzapine DMPFN6Y Bipolar depression Approved [14]
Methamphetamine DMPM4SK Anxiety Approved [396]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
LYSERGIC ACID DIETHYLAMIDE DMACMLO Addictive disorder 6C50-6C5Z Withdrawn from market [397]
SB 258585 DM2QJKZ Discovery agent N.A. Investigative [398]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [197]
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Drug(s) Affected By Glycine amidinotransferase, mitochondrial (GATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Ammonia DMOEVK6 Coronary artery disease BA80 Approved [399]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
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Drug(s) Affected By 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [289]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [215]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Bortezomib DMNO38U Leukemia Approved [186]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [210]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [381]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rap1 GTPase-GDP dissociation stimulator 1 (RAP1GDS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [328]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [131]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
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Drug(s) Affected By Succinate--CoA ligase subunit alpha, mitochondrial (SUCLG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [400]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [226]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
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Drug(s) Affected By Trifunctional enzyme subunit beta, mitochondrial (HADHB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [146]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [400]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [401]
SB-431542 DM0YOXQ Pulmonary fibrosis CB03.4 Preclinical [402]
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Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [403]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [392]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 6 (EIF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [404]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
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Drug(s) Affected By Breast cancer anti-estrogen resistance protein 1 (BCAR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [136]
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Drug(s) Affected By Protein transport protein Sec61 subunit beta (SEC61B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [289]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [213]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [394]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
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Drug(s) Affected By Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [405]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [406]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [338]
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Drug(s) Affected By Actin, cytoplasmic 1 (ACTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Selenium DM25CGV N. A. N. A. Approved [164]
Etretinate DM2CZFA Keratosis ED56 Approved [360]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [407]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
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Drug(s) Affected By Actin-related protein 3 (ACTR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [294]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
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Drug(s) Affected By ATP-binding cassette sub-family E member 1 (ABCE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [408]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [409]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [410]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 26S proteasome regulatory subunit 8 (PSMC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
MG-132 DMKA2YS N. A. N. A. Preclinical [411]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
Milchsaure DM462BT Pruritus EC90 Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein uS17 (RPS11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Bortezomib DMNO38U Leukemia Approved [186]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [413]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [414]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [278]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho-related GTP-binding protein RhoB (RHOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [415]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [416]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [417]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding nuclear protein Ran (RAN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [418]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [419]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [420]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [421]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [422]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein eL30 (RPL30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein uL5 (RPL11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
AHPN DM8G6O4 Discovery agent N.A. Investigative [423]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [190]
[3H]methyltrienolone DMTSGOW Discovery agent N.A. Investigative [424]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [288]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Transformer-2 protein homolog beta (TRA2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [231]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [425]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [363]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By S-phase kinase-associated protein 1 (SKP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [426]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [427]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Arsenic DMTL2Y1 N. A. N. A. Approved [428]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein RACK1 (RACK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [429]
Quercetin DM3NC4M Obesity 5B81 Approved [272]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [430]
Testosterone DM7HUNW Hot flushes GA30 Approved [430]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Nandrolone DMFWKG1 Osteoporosis FB83.0 Approved [431]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [427]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BOS complex subunit NOMO3 (NOMO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Dermcidin (DCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [432]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
SB-431542 DM0YOXQ Pulmonary fibrosis CB03.4 Preclinical [402]
Drug(s) Affected By Enhancer of rudimentary homolog (ERH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [433]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Arsenic DMTL2Y1 N. A. N. A. Approved [434]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
AHPN DM8G6O4 Discovery agent N.A. Investigative [423]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein eL19 (RPL19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [10]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [435]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [278]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
AHPN DM8G6O4 Discovery agent N.A. Investigative [423]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disabled homolog 2 (DAB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [437]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [438]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [184]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein Dr1 (DR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Haloperidol DM96SE0 Delirium Approved [10]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Melanocyte-stimulating hormone receptor (MC1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [439]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [440]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [440]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [440]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [440]
Puerarin DMJIMXH Alcohol dependence 6C40.2 Phase 2 [440]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pro-neuregulin-1, membrane-bound isoform (NRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [352]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [201]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanine nucleotide-binding protein subunit alpha-12 (GNA12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [441]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone-lysine N-methyltransferase 2A (KMT2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [442]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [443]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ethanol DMDRQZU Chronic pain MG30 Approved [444]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [445]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurogenic locus notch homolog protein 2 (NOTCH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [443]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [446]
Bortezomib DMNO38U Leukemia Approved [186]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cleavage stimulation factor subunit 1 (CSTF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [230]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [381]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Elongation factor 1-alpha 2 (EEF1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [376]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [448]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [198]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [449]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoskeleton-associated protein 4 (CKAP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [389]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [215]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [450]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [182]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Golgin subfamily A member 3 (GOLGA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [451]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibrinogen-like protein 1 (FGL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [312]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [452]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone-binding protein RBBP4 (RBBP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [148]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear cap-binding protein subunit 1 (NCBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [453]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [277]
PP-242 DM2348V Discovery agent N.A. Investigative [454]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TBC1 domain family member 8B (TBC1D8B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [455]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
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Drug(s) Affected By Nuclear pore complex protein Nup160 (NUP160)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [231]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
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Drug(s) Affected By Transducin beta-like protein 3 (TBL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [410]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
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Drug(s) Affected By Aspartyl/asparaginyl beta-hydroxylase (ASPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
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Drug(s) Affected By SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [456]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
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Drug(s) Affected By Oviduct-specific glycoprotein (OVGP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [457]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [458]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
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Drug(s) Affected By Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (AIMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [459]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [460]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [304]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
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Drug(s) Affected By Serine/arginine-rich splicing factor 5 (SRSF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [461]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [462]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [463]
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Drug(s) Affected By Bcl-2-interacting killer (BIK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [464]
Methotrexate DM2TEOL Anterior urethra cancer Approved [465]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [466]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [467]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [468]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Menthol DMG2KW7 Back pain ME84.Z Approved [236]
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Drug(s) Affected By C-terminal-binding protein 1 (CTBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Selenium DM25CGV N. A. N. A. Approved [164]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [469]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [280]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [136]
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Drug(s) Affected By NAD(P) transhydrogenase, mitochondrial (NNT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [470]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [470]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
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Drug(s) Affected By Stromal interaction molecule 1 (STIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [471]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
USNIC ACID DMGOURX Discovery agent N.A. Investigative [473]
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Drug(s) Affected By Sorting nexin-1 (SNX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [474]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [217]
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Drug(s) Affected By Cullin-2 (CUL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [413]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
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Drug(s) Affected By Isopentenyl-diphosphate Delta-isomerase 1 (IDI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [151]
Fluoxetine DM3PD2C Bipolar depression Approved [153]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [296]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
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Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [475]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [348]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [182]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein DGCR6 (DGCR6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
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Drug(s) Affected By Single-minded homolog 2 (SIM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [217]
geraniol DMS3CBD Discovery agent N.A. Investigative [476]
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Drug(s) Affected By Dihydropyrimidinase-related protein 3 (DPYSL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
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Drug(s) Affected By Src substrate cortactin (CTTN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [477]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [297]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
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Drug(s) Affected By Flotillin-2 (FLOT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Selenium DM25CGV N. A. N. A. Approved [164]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
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Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [125]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [478]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [479]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
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Drug(s) Affected By Protein RRP5 homolog (PDCD11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [177]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [480]
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Drug(s) Affected By Golgin subfamily B member 1 (GOLGB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [455]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [213]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
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Drug(s) Affected By Chromodomain-helicase-DNA-binding protein 4 (CHD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
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Drug(s) Affected By Condensin complex subunit 2 (NCAPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [481]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [171]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [482]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
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Drug(s) Affected By Inorganic pyrophosphatase (PPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
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Drug(s) Affected By Periodic tryptophan protein 2 homolog (PWP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [219]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [483]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [483]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [484]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly(rC)-binding protein 1 (PCBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Selenium DM25CGV N. A. N. A. Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [485]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [486]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [486]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Scaffold attachment factor B1 (SAFB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Bortezomib DMNO38U Leukemia Approved [186]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [136]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein RP/EB family member 1 (MAPRE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [487]
Paclitaxel DMLB81S Breast carcinoma Approved [488]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disks large homolog 2 (DLG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [489]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [453]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [238]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [213]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 7 (SRSF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2A type 2-C (H2AC20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [376]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [328]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [490]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [294]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [367]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [491]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By La-related protein 7 (LARP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [218]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [492]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [358]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [493]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [394]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endoribonuclease LACTB2 (LACTB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-actin-like protein 2 (ACTBL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [360]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [322]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [494]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [278]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [495]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [496]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [497]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [277]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATPase family AAA domain-containing protein 3B (ATAD3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [232]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [498]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By CD276 antigen (CD276)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [331]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [499]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [175]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Microtubule-associated protein 1S (MAP1S)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin-binding LIM protein 2 (ABLIM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [500]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [500]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [500]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [173]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [174]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [501]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Enhancer of mRNA-decapping protein 4 (EDC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [483]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Leiomodin-2 (LMOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ethanol DMDRQZU Chronic pain MG30 Approved [502]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Septin-14 (SEPTIN14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
Drug(s) Affected By Probable ATP-dependent RNA helicase DDX46 (DDX46)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [321]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By eIF5-mimic protein 2 (BZW1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [494]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [288]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent RNA helicase DHX30 (DHX30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [231]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [394]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable helicase senataxin (SETX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [297]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [297]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [297]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleoporin p54 (NUP54)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Low-density lipoprotein receptor-related protein 10 (LRP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [92]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein V (CENPV)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [311]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding Raly-like protein (RALYL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
Drug(s) Affected By THO complex subunit 4 (ALYREF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [503]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GRIP and coiled-coil domain-containing protein 2 (GCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [455]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [197]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Cell division cycle and apoptosis regulator protein 1 (CCAR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [324]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Paclitaxel DMLB81S Breast carcinoma Approved [504]
Bortezomib DMNO38U Leukemia Approved [505]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [506]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [505]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paraneoplastic antigen Ma1 (PNMA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (NUDT10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DIADENOSINE TETRAPHOSPHATE DMTJOEL Cardiac arrhythmias BC9Z Phase 2 [507]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [228]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [508]
Drug(s) Affected By Nuclear protein localization protein 4 homolog (NPLOC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Milchsaure DM462BT Pruritus EC90 Investigative [412]
[3H]methyltrienolone DMTSGOW Discovery agent N.A. Investigative [509]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By TBC1 domain family member 15 (TBC1D15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [455]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PEST proteolytic signal-containing nuclear protein (PCNP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (DHX38)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Haloperidol DM96SE0 Delirium Approved [10]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [510]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nectin-2 (NECTIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [494]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Methotrexate DM2TEOL Anterior urethra cancer Approved [226]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [179]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Menthol DMG2KW7 Back pain ME84.Z Approved [236]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [92]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [511]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Major histocompatibility complex class I-related gene protein (MR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [325]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [325]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [325]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [201]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [325]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [325]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [325]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [274]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Liver-expressed antimicrobial peptide 2 (LEAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [241]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA topoisomerase I, mitochondrial (TOP1MT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [395]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [512]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By PAT complex subunit CCDC47 (CCDC47)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [513]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [230]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Far upstream element-binding protein 1 (FUBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [339]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [361]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [383]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SH3 domain-containing kinase-binding protein 1 (SH3KBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [140]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ADP-ribosylation factor-like protein 8A (ARL8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Bortezomib DMNO38U Leukemia Approved [186]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 14B (PPP1R14B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [247]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [247]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [514]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [515]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BTB/POZ domain-containing protein KCTD12 (KCTD12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [516]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [192]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Ethanol DMDRQZU Chronic pain MG30 Approved [502]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein mS39 (PTCD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [188]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [517]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [230]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PDZ and LIM domain protein 5 (PDLIM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Haloperidol DM96SE0 Delirium Approved [10]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein phosphatase PGAM5, mitochondrial (PGAM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [480]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate decarboxylase 1 (GAD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [518]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [519]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [466]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-7 (PSMB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [520]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [521]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [277]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleosome assembly protein 1-like 4 (NAP1L4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [450]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [483]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [337]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane 9 superfamily member 2 (TM9SF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [195]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Copine-1 (CPNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [294]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [294]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [321]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-48 DMPIM9L N. A. N. A. Patented [335]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By T-complex protein 1 subunit eta (CCT7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [450]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [388]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 3 (NCAPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [375]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myb-binding protein 1A (MYBBP1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [510]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coronin-1B (CORO1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [522]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
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Drug(s) Affected By Histone H2A.J (H2AJ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [175]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [246]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By MKI67 FHA domain-interacting nucleolar phosphoprotein (NIFK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [462]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [523]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor-binding protein 2 (FGFBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [524]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [525]
Drug(s) Affected By Apoptosis facilitator Bcl-2-like protein 14 (BCL2L14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [489]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [468]
Menthol DMG2KW7 Back pain ME84.Z Approved [236]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [526]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [231]
Fenretinide DMRD5SP Macular degeneration 9B78.3 Phase 3 [527]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [528]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [529]
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [530]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [531]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [532]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [533]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [405]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [534]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth hormone-inducible transmembrane protein (GHITM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [155]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Damage-control phosphatase ARMT1 (ARMT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exosome complex component RRP41 (EXOSC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [164]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [215]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [486]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF13B (KIF13B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [438]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [535]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine incorporator 1 (SERINC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phenylalanine--tRNA ligase beta subunit (FARSB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATPase family AAA domain-containing protein 3A (ATAD3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [357]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [185]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [536]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [498]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endoplasmic reticulum aminopeptidase 1 (ERAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [479]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Very-long-chain (HACD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
EMODIN DMAEDQG Coronavirus Disease 2019 (COVID-19) 1D6Y Terminated [537]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
Milchsaure DM462BT Pruritus EC90 Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [377]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [538]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [498]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [539]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribosome-binding protein 1 (RRBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [339]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [516]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [324]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [540]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ataxin-10 (ATXN10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [541]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [235]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [490]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Menthol DMG2KW7 Back pain ME84.Z Approved [236]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily B member 11 (DNAJB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [523]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [542]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Testin (TES)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [543]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Translocation protein SEC63 homolog (SEC63)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Indomethacin DMSC4A7 Bursitis Approved [544]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine and histidine-rich domain-containing protein 1 (CHORDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Haloperidol DM96SE0 Delirium Approved [10]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH-cytochrome b5 reductase 1 (CYB5R1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [177]
Bortezomib DMNO38U Leukemia Approved [186]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Testosterone DM7HUNW Hot flushes GA30 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [523]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [189]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [210]
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Drug(s) Affected By Nuclear pore complex protein Nup50 (NUP50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [224]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase TAO2 (TAOK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [426]
Methotrexate DM2TEOL Anterior urethra cancer Approved [146]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Arsenic DMTL2Y1 N. A. N. A. Approved [545]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [496]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sorting nexin-6 (SNX6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [546]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [226]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Translocon-associated protein subunit gamma (SSR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [335]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [547]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Folic Acid DMEMBJC Colorectal carcinoma Approved [100]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein SATB2 (SATB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [516]
Haloperidol DM96SE0 Delirium Approved [10]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [501]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [548]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine repetitive matrix protein 2 (SRRM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [324]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [486]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phenylalanine--tRNA ligase alpha subunit (FARSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Bortezomib DMNO38U Leukemia Approved [186]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [230]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fanconi-associated nuclease 1 (FAN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [151]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [549]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch domain-containing protein 2 (KLHDC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [225]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [496]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thyroid hormone receptor-associated protein 3 (THRAP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [229]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [213]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine-threonine kinase receptor-associated protein (STRAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [429]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [550]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [542]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-splicing ligase RtcB homolog (RTCB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [204]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [551]
Drug(s) Affected By Nucleolar complex protein 2 homolog (NOC2L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [552]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [480]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TRPM8 channel-associated factor 1 (TCAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Haloperidol DM96SE0 Delirium Approved [10]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [197]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Talin-2 (TLN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [10]
Methotrexate DM2TEOL Anterior urethra cancer Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [553]
Haloperidol DM96SE0 Delirium Approved [10]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-secretase 2 (BACE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [223]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [554]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FH1/FH2 domain-containing protein 1 (FHOD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Urethane DM7NSI0 N. A. N. A. Phase 4 [203]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [231]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chloride intracellular channel protein 4 (CLIC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [181]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [433]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Testosterone enanthate DMB6871 N. A. N. A. Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [161]
Benzatropine DMF7EXL Parkinsonian disorder Approved [10]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [231]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [279]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Flavin-containing monooxygenase 3 (FMO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [293]
Perazine DM2AOTZ Psychotic disorder 6A20-6A25 Approved [555]
Almogran DM7I64Z Migraine 8A80 Approved [556]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [557]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [558]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [560]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent dopamine transporter (SLC6A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [561]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [562]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [563]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [564]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [565]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [231]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [566]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disrupted in schizophrenia 1 protein (DISC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [144]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [217]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [131]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [238]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [238]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [567]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxytocin-neurophysin 1 (OXT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [568]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [568]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
Drug(s) Affected By Sodium-dependent serotonin transporter (SLC6A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [569]
Fluoxetine DM3PD2C Bipolar depression Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [570]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [571]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [572]
Quercetin DM3NC4M Obesity 5B81 Approved [121]
Aripiprazole DM3NUMH Bipolar I disorder Approved [573]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [571]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 2C (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [574]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [574]
Fluoxetine DM3PD2C Bipolar depression Approved [574]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [575]
Testosterone DM7HUNW Hot flushes GA30 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dysbindin (DTNBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [172]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [162]
Haloperidol DM96SE0 Delirium Approved [576]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [287]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [205]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [131]
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Drug(s) Affected By 5-hydroxytryptamine receptor 3A (HTR3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [97]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [321]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [577]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [245]
Metoclopramide DMFA5MY Nausea MD90 Approved [578]
Capsaicin DMGMF6V Back pain ME84.Z Approved [579]
Hydromorphone DMHP21E Back pain ME84.Z Approved [580]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [577]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By D(1A) dopamine receptor (DRD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [97]
Haloperidol DM96SE0 Delirium Approved [90]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [581]
Pergolide mesylate DM5GKOV N. A. N. A. Approved [582]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [90]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [583]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [584]
Methamphetamine DMPM4SK Anxiety Approved [585]
Bardoxolone methyl DMODA2X Mixed connective tissue disease 4A43.3 Phase 3 [586]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Circadian locomoter output cycles protein kaput (CLOCK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [587]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [588]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [589]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [590]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [209]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [205]
CGS 21680 DMZ0TGY Discovery agent N.A. Investigative [591]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Flavin-containing monooxygenase 1 (FMO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [244]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [592]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [593]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [531]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [183]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Dihydroxyacetone DMM1LG2 Sunburn EJ40 Approved [594]
Atazanavir DMSYRBX Human immunodeficiency virus infection 1C62 Approved [531]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [105]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 2A (HTR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [97]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [116]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [595]
Haloperidol DM96SE0 Delirium Approved [595]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [91]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [93]
Olanzapine DMPFN6Y Bipolar depression Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [596]
Arsenic DMTL2Y1 N. A. N. A. Approved [187]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [597]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D4 receptor (D4R) TTE0A2F DRD4_HUMAN Modulator [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [6]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [7]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [5]
Cytochrome P450 2A6 (CYP2A6) DEJVYAZ CP2A6_HUMAN Substrate [8]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [9]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein theta OTWG7F3H 1433T_HUMAN Gene/Protein Processing [10]
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) OTB8HCED CN37_HUMAN Gene/Protein Processing [10]
26S proteasome non-ATPase regulatory subunit 14 (PSMD14) OTJWHMZ5 PSDE_HUMAN Gene/Protein Processing [10]
26S proteasome non-ATPase regulatory subunit 7 (PSMD7) OT7PZZ4K PSMD7_HUMAN Gene/Protein Processing [10]
26S proteasome regulatory subunit 6A (PSMC3) OTSKT0JI PRS6A_HUMAN Gene/Protein Processing [10]
26S proteasome regulatory subunit 8 (PSMC5) OTJOORMR PRS8_HUMAN Gene/Protein Processing [10]
5-hydroxytryptamine receptor 2A (HTR2A) OTWXJX0M 5HT2A_HUMAN Drug Response [11]
5-hydroxytryptamine receptor 2C (HTR2C) OT6H8DE0 5HT2C_HUMAN Drug Response [12]
5-hydroxytryptamine receptor 3A (HTR3A) OTAIV1AK 5HT3A_HUMAN Drug Response [13]
5-hydroxytryptamine receptor 6 (HTR6) OT8GTDDY 5HT6R_HUMAN Protein Interaction/Cellular Processes [14]

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128 Global molecular effects of tocilizumab therapy in rheumatoid arthritis synovium. Arthritis Rheumatol. 2014 Jan;66(1):15-23.
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133 MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia. Cell Biol Toxicol. 2023 Feb;39(1):201-216. doi: 10.1007/s10565-021-09639-4. Epub 2021 Sep 28.
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135 Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity. Toxicol Appl Pharmacol. 2019 Jan 1;362:150-158. doi: 10.1016/j.taap.2018.11.002. Epub 2018 Nov 10.
136 Arsenite and cadmium promote the development of mammary tumors. Carcinogenesis. 2020 Jul 14;41(7):1005-1014. doi: 10.1093/carcin/bgz176.
137 Time series analysis of oxidative stress response patterns in HepG2: a toxicogenomics approach. Toxicology. 2013 Apr 5;306:24-34.
138 Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid: Role of NRF2 and FXR pathways. Food Chem Toxicol. 2021 Dec;158:112664. doi: 10.1016/j.fct.2021.112664. Epub 2021 Nov 9.
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140 Keratinocyte-derived IL-36gama plays a role in hydroquinone-induced chemical leukoderma through inhibition of melanogenesis in human epidermal melanocytes. Arch Toxicol. 2019 Aug;93(8):2307-2320.
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