Details of Disease

General Information of Disease (ID: DISCEMGC)

Disease Name Cytomegalovirus infection
Synonyms Cytomegaloviral infection; HCMV infection; CMV infection
Disease Class 1D82: Cytomegaloviral disease
Definition
A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies.
Disease Hierarchy
DISDI77C: Primary viral infectious disease
DISEM33Q: Infectious disease
DISCEMGC: Cytomegalovirus infection
ICD Code
ICD-11
ICD-11: 1D82
Expand ICD-11
'1D82
Expand ICD-10
'B25; 'B25.0; 'B25.8; 'B25.9
Disease Identifiers
MONDO ID
MONDO_0005132
MESH ID
D003586
UMLS CUI
C0010823
MedGen ID
8239
SNOMED CT ID
28944009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 5 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Cidofovir DMA13GD Approved Small molecular drug [1]
CytoGam DMEC57G Approved NA [2]
Ganciclovir DM1MBYQ Approved Small molecular drug [3]
Maribavir DM3GTAL Approved Small molecular drug [4]
MK-8228 DMOB58Q Approved Small molecular drug [5]
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This Disease is Treated as An Indication in 13 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ASP0113 DMVA8KU Phase 3 Vaccine [6]
Cytotect CP DMBI8RZ Phase 3 NA [7]
SHP620 DM1SFXG Phase 3 NA [8]
CMVpp65-A0201 DM7GELO Phase 2 Vaccine [9]
RG7667 DMHXODU Phase 2 NA [10]
Triplex DMH3T2E Phase 2 Vaccine [11]
V160 DM6NF26 Phase 2 NA [12]
AVX-601 DM6WZOE Phase 1 NA [13]
CMV glycoprotein B subunit vaccine DM6NG3C Phase 1 Vaccine [14]
GSK3993129A? DM8OWQ8 Phase 1 Vaccine [15]
MBX400 DM3TNMJ Phase 1 NA [16]
TCN-202 DM09107 Phase 1 NA [17]
ATA230 DM9LXTJ Clinical trial Cell therapy [18]
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⏷ Show the Full List of 13 Drug(s)
This Disease is Treated as An Indication in 10 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ISIS 2922 DMGTBC7 Withdrawn from market Antisense drug [2]
Regavirumab DMF3PZ5 Discontinued in Preregistration Monoclonal antibody [19]
CMV vaccine DM10V4Y Discontinued in Phase 1 NA [20]
ANX-201 DMOJP9E Terminated Small molecular drug [22]
AR-132 DMF8I80 Terminated NA [23]
BEA-005 DM6KRJW Terminated Small molecular drug [24]
DES-6 DMKWVTD Terminated NA [25]
GVX-3322 DM9SEP3 Terminated NA [26]
Human Cytomegalovirus vaccine DM3YZ2L Terminated NA [27]
PG-36 DMJ5FKI Terminated NA [28]
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⏷ Show the Full List of 10 Drug(s)
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CMV DNA vaccine DMCHGQE Preclinical NA [21]
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This Disease is Treated as An Indication in 7 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
4Ab-028 DMMSLM8 Investigative NA [29]
Anti-CMV mabs DMH2YRI Investigative Monoclonal antibody [29]
CMV-specific STAR fusions DMO4YLL Investigative NA [29]
CyMVectin DM7VYL4 Investigative NA [29]
HPMPA prodrugs DM0CO0U Investigative NA [29]
INA-115E DM7XLG3 Investigative NA [29]
VPM-2-001 DM21TFZ Investigative NA [29]
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⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 51 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CD28 TTQ13FT Limited Biomarker [30]
GJB2 TTRGZX3 Limited Genetic Variation [31]
IRF3 TTYR7OH Limited Altered Expression [32]
ISG15 TTVOH3T Limited Altered Expression [32]
LILRB1 TTC0QRJ Limited Altered Expression [33]
PML TTLH9NY Limited Biomarker [34]
STAT1 TTN7R6K Disputed Biomarker [35]
AOC3 TT7HC21 Strong Biomarker [36]
APOBEC3G TTP96KH Strong Altered Expression [37]
BTLA TTER58P Strong Altered Expression [38]
CCR5 TTJIH8Q Strong Biomarker [39]
CD1A TTBGTFN Strong Biomarker [40]
CD209 TTBXIM9 Strong Genetic Variation [41]
CD27 TTDO1MV Strong Biomarker [42]
CD300A TTI2YFK Strong Altered Expression [43]
CD34 TTZAVYN Strong Biomarker [44]
CD58 TT5KSBY Strong Biomarker [45]
CD83 TTT9MRQ Strong Altered Expression [46]
CD9 TTZEIBV Strong Altered Expression [47]
DNM1 TTE3JW9 Strong Biomarker [48]
DOT1L TTSZ8T1 Strong Biomarker [49]
FCGRT TTKLPHO Strong Biomarker [50]
FUS TTKGYZ9 Strong Biomarker [51]
GAN TT6WNG2 Strong Genetic Variation [52]
GMNN TT390KA Strong Altered Expression [53]
HDC TTV9GOF Strong Genetic Variation [54]
IKBKB TTJ3E9X Strong Biomarker [55]
IL31RA TT9HPX0 Strong Biomarker [56]
KIR2DL1 TT4UXPE Strong Biomarker [57]
KIR2DL2 TTU0P73 Strong Genetic Variation [58]
KIR2DL3 TTEX3SI Strong Biomarker [58]
KIR2DS1 TTVWAGF Strong Biomarker [59]
KLRC1 TTC4IMS Strong Biomarker [60]
KLRG1 TT299E6 Strong Altered Expression [42]
MGAT1 TTYJRN5 Strong Biomarker [61]
NAAA TTMN4HY Strong Genetic Variation [62]
NCOA4 TT8OY02 Strong Altered Expression [63]
NCR1 TTQNRJM Strong Biomarker [64]
PPIB TT6ZFQ4 Strong Biomarker [65]
RGS6 TTJ96M8 Strong Biomarker [66]
RORC TTGV6LY Strong Genetic Variation [67]
SCAP TTL6U2P Strong Altered Expression [68]
SCT TTOBVIN Strong Biomarker [54]
SLITRK6 TTTVEKI Strong Altered Expression [69]
SREBF1 TTER0UB Strong Altered Expression [70]
SUCNR1 TT4FX9Y Strong Altered Expression [71]
SYVN1 TT8XKYM Strong Biomarker [72]
TACR3 TTBPGLU Strong Biomarker [73]
TLR2 TTY7ZHS Strong Genetic Variation [74]
WDR5 TT7OFWB Strong Altered Expression [75]
VCP TTHNLSB Definitive Biomarker [76]
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⏷ Show the Full List of 51 DTT(s)
This Disease Is Related to 1 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC11A1 DT650XW Strong Genetic Variation [77]
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This Disease Is Related to 1 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
CYP7A1 DEDZRQ1 Strong Altered Expression [78]
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This Disease Is Related to 107 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
B3GAT1 OTXFP98E Limited Altered Expression [42]
CSH1 OT33HTRR Limited Biomarker [79]
CSH2 OTW8JVAN Limited Biomarker [79]
ACAD8 OT3JI5GB Strong Biomarker [80]
AGO2 OT4JY32Q Strong Biomarker [81]
AIM2 OT86QUI8 Strong Biomarker [82]
AMPD1 OTU17BCI Strong Altered Expression [83]
ANAPC4 OTVW4DW1 Strong Biomarker [84]
ANAPC5 OTGTJNNR Strong Biomarker [84]
APBA1 OTUH9JPD Strong Biomarker [48]
APMAP OT1P2GJA Strong Biomarker [85]
APOBEC3A OTYO6F5P Strong Biomarker [86]
ATP11A OT7M9ZDK Strong Biomarker [87]
ATP6V0C OTKPL09B Strong Biomarker [87]
AZIN2 OT8OB7CG Strong Biomarker [88]
BCLAF1 OT7T8H6A Strong Biomarker [89]
BRCC3 OTK0ZN7Y Strong Altered Expression [90]
C1orf52 OT8RQW3W Strong Biomarker [91]
CCL8 OTCTWYN8 Strong Biomarker [92]
CCNT1 OTDYVGCP Strong Biomarker [93]
CD200R1 OT65Q9M6 Strong Biomarker [94]
CD244 OTSMR85N Strong Altered Expression [95]
CD300C OT4BSR7D Strong Genetic Variation [96]
CELF5 OT02OG9N Strong Biomarker [97]
CHP1 OTHTXN1A Strong Altered Expression [47]
CISH OT8T5NYL Strong Altered Expression [98]
CKB OTUCKOTT Strong Biomarker [99]
COL17A1 OTID5AH2 Strong Biomarker [100]
COPB2 OT82JIGC Strong Biomarker [101]
CTNNBIP1 OTX9SBJG Strong Altered Expression [102]
DDX21 OTV73GMZ Strong Altered Expression [103]
DEPDC1B OTMVFOT1 Strong Altered Expression [90]
DNAH8 OTGES2OU Strong Altered Expression [104]
EIF4A2 OT08H03R Strong Altered Expression [105]
EIF4G1 OT2CF1E6 Strong Altered Expression [105]
ELOVL7 OT89NYVC Strong Biomarker [106]
EN2 OT7EZCM2 Strong Biomarker [107]
EOMES OTB9VQFA Strong Biomarker [108]
GABARAPL2 OTS7YVHF Strong Biomarker [109]
GADL1 OTJM4A0R Strong Biomarker [88]
GCA OTAJ7ZHG Strong Genetic Variation [110]
GNLY OTZJKA8C Strong Altered Expression [65]
GSDMD OTH39BKI Strong Biomarker [111]
GTF2H4 OTPD1DIU Strong Biomarker [112]
GZMM OTEC5CWT Strong Altered Expression [113]
HLA-C OTV38BUJ Strong Biomarker [114]
HLA-E OTX1CTFB Strong Altered Expression [115]
IFI16 OT4SPU0U Strong Biomarker [116]
IFIT1 OTXOQDSG Strong Biomarker [117]
INA OT1D33T4 Strong Biomarker [118]
INSIG1 OTZF5X1D Strong Altered Expression [68]
KIR2DL5A OT09FZE1 Strong Genetic Variation [119]
KIR2DL5B OTSV0JL9 Strong Genetic Variation [119]
KIR2DS4 OT00N6UJ Strong Biomarker [120]
KLF12 OTVH4KD4 Strong Biomarker [121]
KLRB1 OTQ2959Y Strong Altered Expression [43]
LGALS9 OT7MF91K Strong Biomarker [122]
LRRC4 OT7XJ70N Strong Biomarker [91]
MCF2L OTEURA8N Strong Biomarker [123]
MEPE OTXJRUW0 Strong Biomarker [124]
MICA OTPEIEAR Strong Genetic Variation [125]
MLXIPL OTR9MLLW Strong Biomarker [70]
MNT OTPC4ANL Strong Altered Expression [83]
MYO5B OTCKL3W3 Strong Genetic Variation [126]
NABP2 OTQU8081 Strong Altered Expression [127]
NCR3LG1 OT15YWU7 Strong Altered Expression [128]
NEFH OTMSCW5I Strong Biomarker [118]
NEFM OT8VCBNF Strong Biomarker [118]
NFE2L1 OT1QHOS2 Strong Biomarker [129]
NGDN OTBXTCN5 Strong Biomarker [130]
NGLY1 OTZBQD5Q Strong Biomarker [61]
NMS OTFYS4LO Strong Biomarker [76]
NRF1 OTOXWNV8 Strong Biomarker [129]
NRSN1 OT1KKXC8 Strong Altered Expression [47]
NSF OTKRJ2ZT Strong Biomarker [48]
NT5C1A OTS7UF36 Strong Biomarker [67]
PAX9 OT25J0F7 Strong Genetic Variation [131]
PHF13 OT89FV4A Strong Biomarker [132]
PRC1 OTHD0XS0 Strong Biomarker [133]
QRSL1 OTJDU2UG Strong Biomarker [134]
RAG1 OTV131E4 Strong Genetic Variation [135]
RAPGEF5 OT53VS75 Strong Altered Expression [136]
RPE OT0XT3JU Strong Altered Expression [137]
RPL17 OTTYMPS6 Strong Genetic Variation [138]
RPL26 OTFNRC27 Strong Biomarker [139]
RPL5 OTM8EBRI Strong Biomarker [140]
RPS11 OTILZE44 Strong Altered Expression [141]
RSAD2 OTCA9WCM Strong Biomarker [142]
SAMHD1 OTBCIBC7 Strong Biomarker [143]
SERPINB9 OTJ811IF Strong Biomarker [144]
SIGLEC12 OTC36XP9 Strong Biomarker [145]
SIX3 OTP5E3VU Strong Biomarker [146]
SLC25A41 OTVFKZXV Strong Biomarker [84]
SLN OTERIU75 Strong Biomarker [147]
SP100 OTN8SD5W Strong Altered Expression [148]
SPEN OT37A2MD Strong Biomarker [91]
SSB OTCCTPBR Strong Altered Expression [149]
SSBP1 OTH2PZWH Strong Biomarker [127]
STAT2 OTO9G2RZ Strong Biomarker [150]
SUMO1 OTJFD4P5 Strong Altered Expression [151]
SUMO2 OT1Y5IKN Strong Altered Expression [151]
SUMO3 OTTUJQJ1 Strong Altered Expression [151]
TMED2 OTBLO7RW Strong Altered Expression [47]
TPPP OTCFMSUF Strong Altered Expression [47]
TRIM29 OT2DNESG Strong Biomarker [152]
CTNNA3 OT9Z0P1E Definitive Genetic Variation [153]
KLRD1 OTMYLOV4 Definitive Altered Expression [154]
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⏷ Show the Full List of 107 DOT(s)

References

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2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Ganciclovir FDA Label
4 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 215596.
5 The novel anticytomegalovirus compound AIC246 (Letermovir) inhibits human cytomegalovirus replication through a specific antiviral mechanism that involves the viral terminase. J Virol. 2011 Oct;85(20):10884-93.
6 ClinicalTrials.gov (NCT01877655) A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT). U.S. National Institutes of Health.
7 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031117)
8 ClinicalTrials.gov (NCT02927067) A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants. U.S. National Institutes of Health.
9 ClinicalTrials.gov (NCT02396134) Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant. U.S. National Institutes of Health.
10 ClinicalTrials.gov (NCT01753167) A Study of RG7667 for the Prevention of Cytomegalovirus Disease in Kidney Transplant Recipients. U.S. National Institutes of Health.
11 ClinicalTrials.gov (NCT05099965) Phase II, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA)-Based Anti-Cytomegalovirus (CMV) Vaccine (Triplex?), in Adults With Both Human Immunodeficiency Virus (HIV)-1 and CMV Who Are on Potent Combination ART With Conserved Immune Function. U.S.National Institutes of Health.
12 ClinicalTrials.gov (NCT03486834) Safety, Tolerability, and Efficacy of the Human Cytomegalovirus Vaccine (V160) in Healthy Women 16 to 35 Years of Age (V160-002). U.S. National Institutes of Health.
13 ClinicalTrials.gov (NCT00439803) A Clinical Trial of an Alphavirus Replicon Vaccine for Cytomegalovirus (CMV). U.S. National Institutes of Health.
14 ClinicalTrials.gov (NCT00435396) Study to Evaluate Safety and Immunogenicity of the GSK Bio CMV Vaccine in CMV-seronegative Healthy Male Adult Subjects. U.S. National Institutes of Health.
15 Clinical pipeline report, company report or official report of GlaxoSmithKline
16 Meeting report: 27th International conference on antiviral research, in Raleigh, NC, USA. Antiviral Research Volume 111, November 2014, Pages 143-153.
17 ClinicalTrials.gov (NCT01594437) Safety Study of Human Anti-Cytomegalovirus Monoclonal Antibody. U.S. National Institutes of Health.
18 ClinicalTrials.gov (NCT03010332) An Expanded Access Protocol of ATA230 (Third-Party Donor-Derived Cytomegalovirus-Specific T Cells) for the Treatment of CMV Viremia or Disease in Subjects for Whom There Are No Other Comparable Options. U.S.National Institutes of Health.
19 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003172)
20 Influenza virus vaccine live intranasal--MedImmune vaccines: CAIV-T, influenza vaccine live intranasal. Drugs R D. 2003;4(5):312-9.
21 Clinical pipeline report, company report or official report of Vical.
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23 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006519)
24 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008999)
25 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018986)
26 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027021)
27 Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex. PLoS Pathog. 2014 Nov 20;10(11):e1004524.
28 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005799)
29 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
30 Assigning Cytomegalovirus Status in Children Awaiting Organ Transplant: Viral Shedding, CMV-Specific T Cells, and CD27-CD28-CD4+ T Cells.J Infect Dis. 2018 Sep 8;218(8):1205-1209. doi: 10.1093/infdis/jiy309.
31 Does congenital cytomegalovirus infection lead to hearing loss by inducing mutation of the GJB2 gene?.Pediatr Res. 2013 Aug;74(2):121-6. doi: 10.1038/pr.2013.77. Epub 2013 May 10.
32 Interferon-Independent Upregulation of Interferon-Stimulated Genes during Human Cytomegalovirus Infection is Dependent on IRF3 Expression.Viruses. 2019 Mar 12;11(3):246. doi: 10.3390/v11030246.
33 Effect of cytomegalovirus infection and leukocyte immunoglobulin like receptor B1 polymorphisms on receptor expression in peripheral blood mononuclear cells.Microbiol Immunol. 2018 Dec;62(12):755-762. doi: 10.1111/1348-0421.12661.
34 Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0.J Virol. 2018 Nov 12;92(23):e01452-18. doi: 10.1128/JVI.01452-18. Print 2018 Dec 1.
35 Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.Cell Rep. 2019 Feb 26;26(9):2394-2406.e5. doi: 10.1016/j.celrep.2019.02.017.
36 Induction of vascular adhesion protein-1 during liver allograft rejection and concomitant cytomegalovirus infection in rats.Am J Pathol. 2000 Oct;157(4):1229-37. doi: 10.1016/S0002-9440(10)64638-X.
37 Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity.J Virol. 2018 Sep 12;92(19):e01224-18. doi: 10.1128/JVI.01224-18. Print 2018 Oct 1.
38 B and T lymphocyte attenuator is highly expressed on CMV-specific T cells during infection and regulates their function.J Immunol. 2010 Sep 15;185(6):3140-8. doi: 10.4049/jimmunol.0902487. Epub 2010 Aug 6.
39 The Chemokine Receptor CXCR3 Promotes CD8(+) T Cell Accumulation in Uninfected Salivary Glands but Is Not Necessary after Murine Cytomegalovirus Infection.J Immunol. 2018 Feb 1;200(3):1133-1145. doi: 10.4049/jimmunol.1701272. Epub 2017 Dec 29.
40 Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue.Virology. 2007 Dec 5;369(1):55-68. doi: 10.1016/j.virol.2007.07.008. Epub 2007 Aug 22.
41 Association between individual and combined SNPs in genes related to innate immunity and incidence of CMV infection in seropositive kidney transplant recipients.Am J Transplant. 2015 May;15(5):1323-35. doi: 10.1111/ajt.13107. Epub 2015 Mar 16.
42 Early KLRG1(+) but Not CD57(+)CD8(+) T Cells in Primary Cytomegalovirus Infection Predict Effector Function and Viral Control.J Immunol. 2019 Oct 15;203(8):2063-2075. doi: 10.4049/jimmunol.1900399. Epub 2019 Sep 25.
43 Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations.Front Immunol. 2017 Jun 2;8:649. doi: 10.3389/fimmu.2017.00649. eCollection 2017.
44 Cytomegalovirus Infection in Allogeneic Hematopoietic Cell Transplantation Managed by the Preemptive Approach: Estimating the Impact on Healthcare Resource Utilization and Outcomes.Biol Blood Marrow Transplant. 2019 Apr;25(4):791-799. doi: 10.1016/j.bbmt.2018.11.012. Epub 2018 Nov 24.
45 Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24.
46 The Major Immediate-Early Protein IE2 of Human Cytomegalovirus Is Sufficient to Induce Proteasomal Degradation of CD83 on Mature Dendritic Cells.Front Microbiol. 2017 Feb 1;8:119. doi: 10.3389/fmicb.2017.00119. eCollection 2017.
47 Human cytomegalovirus infection reduces surface CCR5 expression in human microglial cells, astrocytes and monocyte-derived macrophages.Microbes Infect. 2002 Nov;4(14):1401-8. doi: 10.1016/s1286-4579(02)00022-9.
48 NSF, Unc-18-1, dynamin-1 and HSP90 are inclusion body components in neuronal intranuclear inclusion disease identified by anti-SUMO-1-immunocapture.Acta Neuropathol. 2008 Dec;116(6):603-14. doi: 10.1007/s00401-008-0437-4. Epub 2008 Oct 3.
49 Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection.Mol Cell Proteomics. 2014 Sep;13(9):2399-410. doi: 10.1074/mcp.M114.039792. Epub 2014 Jul 1.
50 Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor.Nat Commun. 2019 Jul 9;10(1):3020. doi: 10.1038/s41467-019-10865-y.
51 Phenotypic variability within the inclusion body spectrum of basophilic inclusion body disease and neuronal intermediate filament inclusion disease in frontotemporal lobar degenerations with FUS-positive inclusions.J Neuropathol Exp Neurol. 2012 Sep;71(9):795-805. doi: 10.1097/NEN.0b013e318266efb1.
52 Gigaxonin mutation analysis in patients with NIFID.Neurobiol Aging. 2011 Aug;32(8):1528-9. doi: 10.1016/j.neurobiolaging.2009.08.018. Epub 2009 Sep 26.
53 Human cytomegalovirus miR-US5-1 inhibits viral replication by targeting Geminin mRNA.Virol Sin. 2017 Oct;32(5):431-439. doi: 10.1007/s12250-017-4064-x. Epub 2017 Oct 31.
54 Cytomegalovirus Serostatus Affects Autoreactive NK Cells and Outcomes of IL2-Based Immunotherapy in Acute Myeloid Leukemia.Cancer Immunol Res. 2018 Sep;6(9):1110-1119. doi: 10.1158/2326-6066.CIR-17-0711. Epub 2018 Jul 6.
55 The IB Kinases Restrict Human Cytomegalovirus Infection.J Virol. 2019 Apr 17;93(9):e02030-18. doi: 10.1128/JVI.02030-18. Print 2019 May 1.
56 Role of vasodilator-stimulated phosphoprotein in human cytomegalovirus-induced hyperpermeability of human endothelial cells.Exp Ther Med. 2018 Aug;16(2):1295-1303. doi: 10.3892/etm.2018.6332. Epub 2018 Jun 20.
57 KIR Polymorphism Modulates the Size of the Adaptive NK Cell Pool in Human Cytomegalovirus-Infected Individuals.J Immunol. 2019 Oct 15;203(8):2301-2309. doi: 10.4049/jimmunol.1900423. Epub 2019 Sep 13.
58 Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.Int J Mol Sci. 2019 Jan 28;20(3):546. doi: 10.3390/ijms20030546.
59 Expression of KIR2DS1 by decidual natural killer cells increases their ability to control placental HCMV infection.Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15072-15077. doi: 10.1073/pnas.1617927114. Epub 2016 Dec 12.
60 Human cytomegalovirus infection promotes rapid maturation of NK cells expressing activating killer Ig-like receptor in patients transplanted with NKG2C-/- umbilical cord blood.J Immunol. 2014 Feb 15;192(4):1471-9. doi: 10.4049/jimmunol.1302053. Epub 2014 Jan 17.
61 Blocking cellular N-glycosylation suppresses human cytomegalovirus entry in human fibroblasts.Microb Pathog. 2020 Jan;138:103776. doi: 10.1016/j.micpath.2019.103776. Epub 2019 Oct 7.
62 Late cytomegalovirus infection in children: High incidence of allograft rejection and hepatitis in donor negative and seropositive liver transplant recipients.Pediatr Transplant. 2017 May;21(3). doi: 10.1111/petr.12879. Epub 2017 Jan 30.
63 Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.J Virol. 2018 Jun 13;92(13):e00191-18. doi: 10.1128/JVI.00191-18. Print 2018 Jul 1.
64 NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development.Nat Immunol. 2018 Oct;19(10):1083-1092. doi: 10.1038/s41590-018-0209-9. Epub 2018 Sep 17.
65 Transcriptional profiles in urine during acute rejection, bacteriuria, CMV infection and stable graft function after renal transplantation.Scand J Immunol. 2009 Apr;69(4):357-65. doi: 10.1111/j.1365-3083.2009.02226.x.
66 Cytomegaloviruses Exploit Recycling Rab Proteins in the Sequential Establishment of the Assembly Compartment.Front Cell Dev Biol. 2018 Dec 4;6:165. doi: 10.3389/fcell.2018.00165. eCollection 2018.
67 Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients.Cochrane Database Syst Rev. 2019 Dec 16;12(12):CD004290. doi: 10.1002/14651858.CD004290.pub3.
68 PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.PLoS Pathog. 2013;9(4):e1003266. doi: 10.1371/journal.ppat.1003266. Epub 2013 Apr 4.
69 Human cytomegalovirus downregulates SLITRK6 expression through IE2.J Neurovirol. 2017 Feb;23(1):79-86. doi: 10.1007/s13365-016-0475-y. Epub 2016 Aug 16.
70 ChREBP, a glucose-responsive transcriptional factor, enhances glucose metabolism to support biosynthesis in human cytomegalovirus-infected cells.Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1951-6. doi: 10.1073/pnas.1310779111. Epub 2014 Jan 21.
71 Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium.Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3751-8. doi: 10.1167/iovs.10-6722.
72 The Human Cytomegalovirus Nonstructural Glycoprotein UL148 Reorganizes the Endoplasmic Reticulum.mBio. 2019 Dec 10;10(6):e02110-19. doi: 10.1128/mBio.02110-19.
73 Influence of human cytomegalovirus infection on the NK cell receptor repertoire in children.Eur J Immunol. 2010 May;40(5):1418-27. doi: 10.1002/eji.200939898.
74 Arg753Gln Polymorphisms in the Toll-Like Receptor 2 Gene are Associated with Cytomegalovirus Infection in Egyptian Bone Marrow Recipients.Endocr Metab Immune Disord Drug Targets. 2020;20(4):619-624. doi: 10.2174/1871530319666191018124710.
75 WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress.J Virol. 2018 Apr 13;92(9):e00207-18. doi: 10.1128/JVI.00207-18. Print 2018 May 1.
76 The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication.PLoS Pathog. 2017 May 11;13(5):e1006329. doi: 10.1371/journal.ppat.1006329. eCollection 2017 May.
77 Can immune-related genotypes illuminate the immunopathogenesis of cytomegalovirus disease in human immunodeficiency virus-infected patients?.Hum Immunol. 2012 Feb;73(2):168-74. doi: 10.1016/j.humimm.2011.11.005. Epub 2011 Dec 2.
78 Dual-color bioluminescent assay using infected HepG2 cells sheds new light on Chlamydia pneumoniae and human cytomegalovirus effects on human cholesterol 7-hydroxylase (CYP7A1) transcription.Anal Biochem. 2012 Nov 1;430(1):92-6. doi: 10.1016/j.ab.2012.08.003. Epub 2012 Aug 11.
79 Prospective Cohort Study of Congenital Cytomegalovirus Infection during Pregnancy with Fetal Growth Restriction: Serologic Analysis and Placental Pathology.J Pediatr. 2019 Mar;206:42-48.e2. doi: 10.1016/j.jpeds.2018.10.003. Epub 2018 Nov 6.
80 Severe Symptomatic Primary CMV Infection in Inflammatory Bowel Disease Patients with Low Population Seroprevalence.Gastroenterol Res Pract. 2018 Jun 28;2018:1029401. doi: 10.1155/2018/1029401. eCollection 2018.
81 Crispr/Cas9 Mediated Inactivation of Argonaute 2 Reveals its Differential Involvement in Antiviral Responses.Sci Rep. 2017 Apr 21;7(1):1010. doi: 10.1038/s41598-017-01050-6.
82 Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1 Protein during Virion-Mediated Activation of the AIM2 Inflammasome.mBio. 2019 Feb 12;10(1):e02510-18. doi: 10.1128/mBio.02510-18.
83 Cytomegalovirus infection stimulates expression of monocyte-associated mediator genes.J Immunol. 1989 Nov 15;143(10):3343-52.
84 Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.J Virol. 2010 Oct;84(20):10832-43. doi: 10.1128/JVI.01260-10. Epub 2010 Aug 4.
85 Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection.PLoS Pathog. 2019 Jul 29;15(7):e1007914. doi: 10.1371/journal.ppat.1007914. eCollection 2019 Jul.
86 APOBEC3A Is Upregulated by Human Cytomegalovirus (HCMV) in the Maternal-Fetal Interface, Acting as an Innate Anti-HCMV Effector.J Virol. 2017 Nov 14;91(23):e01296-17. doi: 10.1128/JVI.01296-17. Print 2017 Dec 1.
87 Cellular v-ATPase is required for virion assembly compartment formation in human cytomegalovirus infection.Open Biol. 2017 Nov;7(11):160298. doi: 10.1098/rsob.160298.
88 Apparent Diffusion Coefficient Levels and Neurodevelopmental Outcome in Fetuses with Brain MR Imaging White Matter Hyperintense Signal.AJNR Am J Neuroradiol. 2018 Oct;39(10):1926-1931. doi: 10.3174/ajnr.A5802. Epub 2018 Sep 6.
89 BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection.Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9575-80. doi: 10.1073/pnas.1207496109. Epub 2012 May 29.
90 Human cytomegalovirus-encoded miR-US25-1 aggravates the oxidised low density lipoprotein-induced apoptosis of endothelial cells.Biomed Res Int. 2014;2014:531979. doi: 10.1155/2014/531979. Epub 2014 May 8.
91 Evaluation of the AmpliSensor PCR and the SHARP signal detection system for the early prediction of symptomatic CMV infection in solid transplant recipients.J Clin Virol. 1999 Jun;13(1-2):81-94. doi: 10.1016/s1386-6532(99)00013-x.
92 CCL8 and the Immune Control of Cytomegalovirus in Organ Transplant Recipients.Am J Transplant. 2015 Jul;15(7):1882-92. doi: 10.1111/ajt.13207. Epub 2015 Mar 12.
93 Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription.J Virol. 2009 Jun;83(11):5904-17. doi: 10.1128/JVI.02651-08. Epub 2009 Mar 18.
94 Pre-transplant CD200 and CD200R1 concentrations are associated with post-transplant events in kidney transplant recipients.Medicine (Baltimore). 2019 Sep;98(37):e17006. doi: 10.1097/MD.0000000000017006.
95 Cytomegalovirus-Induced Expression of CD244 after Liver Transplantation Is Associated with CD8+ T Cell Hyporesponsiveness to Alloantigen.J Immunol. 2015 Aug 15;195(4):1838-48. doi: 10.4049/jimmunol.1500440. Epub 2015 Jul 13.
96 Asymptomatic CMV infections in long-term renal transplant recipients are associated with the loss of FcR from LIR-1(+) NK cells.Eur J Immunol. 2016 Nov;46(11):2597-2608. doi: 10.1002/eji.201646422. Epub 2016 Sep 26.
97 Human cytomegalovirus UL141 protein interacts with CELF5 and affects viral DNA replication.Mol Med Rep. 2018 Mar;17(3):4657-4664. doi: 10.3892/mmr.2018.8419. Epub 2018 Jan 10.
98 Suppressor of Cytokine Signaling 1 (SOCS1) and SOCS3 Are Stimulated within the Eye during Experimental Murine Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression.J Virol. 2018 Aug 29;92(18):e00526-18. doi: 10.1128/JVI.00526-18. Print 2018 Sep 15.
99 Selective induction of chromosomal gene expression by human cytomegalovirus.Virology. 1988 Sep;166(1):217-28. doi: 10.1016/0042-6822(88)90163-8.
100 Bullous pemphigoid complicated by cytomegalovirus disease as a manifestation of immune reconstitution inflammatory syndrome: retrospective analyses of our institutional cases and literature review.Int J Dermatol. 2018 Feb;57(2):202-208. doi: 10.1111/ijd.13799. Epub 2017 Dec 2.
101 Identification of Host Factors Involved in Human Cytomegalovirus Replication, Assembly, and Egress Using a Two-Step Small Interfering RNA Screen.mBio. 2018 Jun 26;9(3):e00716-18. doi: 10.1128/mBio.00716-18.
102 CTNNBIP1 downregulation is associated with tumor grade and viral infections in gastric adenocarcinoma.J Cell Physiol. 2019 Mar;234(3):2895-2904. doi: 10.1002/jcp.27106. Epub 2018 Aug 4.
103 Dissecting the Role of DDX21 in Regulating Human Cytomegalovirus Replication.J Virol. 2019 Nov 26;93(24):e01222-19. doi: 10.1128/JVI.01222-19. Print 2019 Dec 15.
104 Cytomegalovirus infection increases the expression and activity of ecto-ATPase (CD39) and ecto-5'nucleotidase (CD73) on endothelial cells.FEBS Lett. 2001 Feb 23;491(1-2):21-5. doi: 10.1016/s0014-5793(01)02085-3.
105 Differential role for host translation factors in host and viral protein synthesis during human cytomegalovirus infection.J Virol. 2014 Feb;88(3):1473-83. doi: 10.1128/JVI.02321-13. Epub 2013 Nov 6.
106 Human Cytomegalovirus pUL37x1 Is Important for Remodeling of Host Lipid Metabolism.J Virol. 2019 Oct 15;93(21):e00843-19. doi: 10.1128/JVI.00843-19. Print 2019 Nov 1.
107 Hsa-miR-27b is up-regulated in cytomegalovirus-infected human glioma cells, targets engrailed-2 and inhibits its expression.Exp Biol Med (Maywood). 2017 Jun;242(12):1227-1233. doi: 10.1177/1535370217699535. Epub 2017 Mar 26.
108 Cutting Edge: Divergent Requirement of T-Box Transcription Factors in Effector and Memory NK Cells.J Immunol. 2018 Mar 15;200(6):1977-1981. doi: 10.4049/jimmunol.1700416. Epub 2018 Feb 9.
109 Human cytomegalovirus hijacks the autophagic machinery and LC3 homologs in order to optimize cytoplasmic envelopment of mature infectious particles.Sci Rep. 2019 Mar 14;9(1):4560. doi: 10.1038/s41598-019-41029-z.
110 TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus.PLoS One. 2015 Apr 6;10(4):e0122831. doi: 10.1371/journal.pone.0122831. eCollection 2015.
111 Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida.J Immunol. 2018 Dec 15;201(12):3662-3668. doi: 10.4049/jimmunol.1800788. Epub 2018 Nov 7.
112 Early serodiagnosis of acute human cytomegalovirus infection by enzyme-linked immunosorbent assay using recombinant antigens.J Clin Microbiol. 1994 Apr;32(4):981-6. doi: 10.1128/jcm.32.4.981-986.1994.
113 Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication.Cell Death Differ. 2013 Mar;20(3):419-29. doi: 10.1038/cdd.2012.132. Epub 2012 Oct 26.
114 Ly49R activation receptor drives self-MHC-educated NK cell immunity against cytomegalovirus infection.Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):26768-26778. doi: 10.1073/pnas.1913064117. Epub 2019 Dec 16.
115 Cytomegalovirus-Infected Primary Endothelial Cells Trigger NKG2C+ Natural Killer Cells.J Innate Immun. 2016;8(4):374-85. doi: 10.1159/000445320. Epub 2016 Apr 27.
116 The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.Immunity. 2016 Aug 16;45(2):255-66. doi: 10.1016/j.immuni.2016.06.015. Epub 2016 Aug 2.
117 Antiviral effects of IFIT1 in human cytomegalovirus-infected fetal astrocytes.J Med Virol. 2017 Apr;89(4):672-684. doi: 10.1002/jmv.24674. Epub 2016 Sep 9.
118 Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID).Neurobiol Aging. 2006 May;27(5):778.e1-778.e6. doi: 10.1016/j.neurobiolaging.2005.03.030. Epub 2005 Jul 7.
119 Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.Genes Immun. 2014 Dec;15(8):562-8. doi: 10.1038/gene.2014.53. Epub 2014 Sep 25.
120 Expression of activating KIR2DS2 and KIR2DS4 genes after hematopoietic cell transplantation: relevance to cytomegalovirus infection.Biol Blood Marrow Transplant. 2011 Nov;17(11):1662-72. doi: 10.1016/j.bbmt.2011.04.008. Epub 2011 Apr 29.
121 KLF12 Regulates Mouse NK Cell Proliferation.J Immunol. 2019 Aug 15;203(4):981-989. doi: 10.4049/jimmunol.1900396. Epub 2019 Jul 12.
122 Restriction of Human Cytomegalovirus Infection by Galectin-9.J Virol. 2019 Jan 17;93(3):e01746-18. doi: 10.1128/JVI.01746-18. Print 2019 Feb 1.
123 Modification of CMV DNA detection from dried blood spots for diagnosing congenital CMV infection.J Clin Virol. 2004 Jul;30(3):276-9. doi: 10.1016/j.jcv.2003.11.012.
124 Clinical and Economic Impact of Cytomegalovirus Infection among Children Undergoing Allogeneic Hematopoietic Cell Transplantation.Biol Blood Marrow Transplant. 2019 Jun;25(6):1253-1259. doi: 10.1016/j.bbmt.2018.11.028. Epub 2018 Nov 29.
125 The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients.Front Immunol. 2018 May 8;9:917. doi: 10.3389/fimmu.2018.00917. eCollection 2018.
126 MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity. Nat Genet. 2008 Oct;40(10):1163-5. doi: 10.1038/ng.225. Epub 2008 Aug 24.
127 Down-regulation of single-stranded DNA-binding protein 1 expression induced by HCMV infection promotes lipid accumulation in cells.Braz J Med Biol Res. 2017 Sep 12;50(11):e6389. doi: 10.1590/1414-431X20176389.
128 Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.Sci Rep. 2017 Aug 17;7(1):8661. doi: 10.1038/s41598-017-08866-2.
129 The Human Cytomegalovirus US27 Gene Product Constitutively Activates Antioxidant Response Element-Mediated Transcription through G(), Phosphoinositide 3-Kinase, and Nuclear Respiratory Factor 1.J Virol. 2018 Nov 12;92(23):e00644-18. doi: 10.1128/JVI.00644-18. Print 2018 Dec 1.
130 Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes.Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14182-7. doi: 10.1073/pnas.0605825103. Epub 2006 Sep 7.
131 Interaction between HCMV infection and PAX9 gene polymorphisms in low birth weight infants.J Matern Fetal Neonatal Med. 2016;29(12):2040-3. doi: 10.3109/14767058.2015.1073253. Epub 2015 Aug 26.
132 Chromatin-Remodeling Factor SPOC1 Acts as a Cellular Restriction Factor against Human Cytomegalovirus by Repressing the Major Immediate Early Promoter.J Virol. 2018 Jun 29;92(14):e00342-18. doi: 10.1128/JVI.00342-18. Print 2018 Jul 15.
133 A Noncanonical Function of Polycomb Repressive Complexes Promotes Human Cytomegalovirus Lytic DNA Replication and Serves as a Novel Cellular Target for Antiviral Intervention.J Virol. 2019 Apr 17;93(9):e02143-18. doi: 10.1128/JVI.02143-18. Print 2019 May 1.
134 GATA2 mutation underlies hemophagocytic lymphohistiocytosis in an adult with primary cytomegalovirus infection.J Infect Chemother. 2020 Feb;26(2):252-256. doi: 10.1016/j.jiac.2019.07.002. Epub 2019 Jul 23.
135 Diverse phenotypic and genotypic presentation of RAG1 mutations in two cases with SCID.Clin Exp Med. 2009 Dec;9(4):339-42. doi: 10.1007/s10238-009-0053-1. Epub 2009 May 21.
136 Changes in Glomerular Filtration Rate and Impact on Long-Term Survival among Adults after Hematopoietic Cell Transplantation: A Prospective Cohort Study.Clin J Am Soc Nephrol. 2018 Jun 7;13(6):866-873. doi: 10.2215/CJN.10630917. Epub 2018 Apr 18.
137 Stepwise adaptation of murine cytomegalovirus to cells of a foreign host for identification of host range determinants.Med Microbiol Immunol. 2015 Jun;204(3):461-9. doi: 10.1007/s00430-015-0400-7. Epub 2015 Mar 19.
138 Association between a polymorphism in the human programmed death-1 (PD-1) gene and cytomegalovirus infection after kidney transplantation.J Med Genet. 2010 Jan;47(1):54-8. doi: 10.1136/jmg.2009.068841. Epub 2009 Jul 5.
139 Distinct domains within the human cytomegalovirus U(L)26 protein are important for wildtype viral replication and virion stability.PLoS One. 2014 Feb 5;9(2):e88101. doi: 10.1371/journal.pone.0088101. eCollection 2014.
140 Immune modulation by the human cytomegalovirus-encoded molecule UL18, a mystery yet to be solved.J Immunol. 2008 Jan 1;180(1):19-24. doi: 10.4049/jimmunol.180.1.19.
141 The interaction between endogenous 30S ribosomal subunit protein S11 and Cucumber mosaic virus LS2b protein affects viral replication, infection and gene silencing suppressor activity.PLoS One. 2017 Aug 14;12(8):e0182459. doi: 10.1371/journal.pone.0182459. eCollection 2017.
142 Viperin regulates cellular lipid metabolism during human cytomegalovirus infection.PLoS Pathog. 2013;9(8):e1003497. doi: 10.1371/journal.ppat.1003497. Epub 2013 Aug 1.
143 A viral kinase counteracts in vivo restriction of murine cytomegalovirus by SAMHD1.Nat Microbiol. 2019 Dec;4(12):2273-2284. doi: 10.1038/s41564-019-0529-z. Epub 2019 Sep 23.
144 The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation.J Infect Dis. 2005 Dec 1;192(11):1908-11. doi: 10.1086/497606. Epub 2005 Oct 18.
145 Early detection of cytomegalovirus (CMV) infection in bone marrow transplant patients by reverse transcription-PCR for CMV spliced late gene UL21.5: a two site evaluation.J Clin Virol. 2002 Feb;24(1-2):13-23. doi: 10.1016/s1386-6532(01)00209-8.
146 RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions.J Virol. 2012 May;86(10):5660-73. doi: 10.1128/JVI.06338-11. Epub 2012 Mar 21.
147 Protein and DNA evidences of HCMV infection in primary breast cancer tissues and metastatic sentinel lymph nodes.Cancer Biomark. 2018;21(4):769-780. doi: 10.3233/CBM-170409.
148 Nuclear domain 10 components upregulated via interferon during human cytomegalovirus infection potently regulate viral infection.J Gen Virol. 2017 Jul;98(7):1795-1805. doi: 10.1099/jgv.0.000858.
149 Human cytomegalovirus induces the endoplasmic reticulum chaperone BiP through increased transcription and activation of translation by using the BiP internal ribosome entry site.J Virol. 2010 Nov;84(21):11479-86. doi: 10.1128/JVI.01330-10. Epub 2010 Aug 25.
150 Differential relocation and stability of PML-body components during productive human cytomegalovirus infection: detailed characterization by live-cell imaging.Eur J Cell Biol. 2010 Oct;89(10):757-68. doi: 10.1016/j.ejcb.2010.05.006.
151 Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments.J Gen Virol. 2013 Jun;94(Pt 6):1373-1384. doi: 10.1099/vir.0.051078-0. Epub 2013 Feb 13.
152 Identification of the E3 Ligase TRIM29 as a Critical Checkpoint Regulator of NK Cell Functions.J Immunol. 2019 Aug 15;203(4):873-880. doi: 10.4049/jimmunol.1900171. Epub 2019 Jul 3.
153 Infection and inflammation in schizophrenia and bipolar disorder: a genome wide study for interactions with genetic variation.PLoS One. 2015 Mar 17;10(3):e0116696. doi: 10.1371/journal.pone.0116696. eCollection 2015.
154 Enrichment of Cytomegalovirus-induced NKG2C+ Natural Killer Cells in the Lung Allograft.Transplantation. 2019 Aug;103(8):1689-1699. doi: 10.1097/TP.0000000000002545.