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2017 FDA drug approvals.Nat Rev Drug Discov. 2018 Feb;17(2):81-85.
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6777).
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URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6912).
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services.
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Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services. 2019
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Phase 3 randomised study of canfosfamide (Telcyta, TLK286) versus pegylated liposomal doxorubicin or topotecan as third-line therapy in patients with platinum-refractory or -resistant ovarian cancer.Eur J Cancer. 2009 Sep;45(13):2324-32.
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ClinicalTrials.gov (NCT01029366) CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy
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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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ClinicalTrials.gov (NCT00942409) Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Non-Hodgkin's Lymphoma (Follicular, Diffuse Large Cell, Mantle Cell, and Small Lymphocytic Lymphoma/Chronic Lymphocytic Leukemia. U.S. National Institutes of Health.
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A phase II, single-arm, open-label, multicenter study to evaluate the efficacy and safety of P276-00, a cyclin-dependent kinase inhibitor, in patients with relapsed or refractory mantle cell lymphoma. Clin Lymphoma Myeloma Leuk. 2015 Jul;15(7):392-7.
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ClinicalTrials.gov (NCT04659044) Polatuzumab Vedotin, Venetoclax, and Rituximab and Hyaluronidase Human for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma. U.S. National Institutes of Health.
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ClinicalTrials.gov (NCT03088878) A Phase 1b/2 Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab (UC-961), and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in Patients With B-Cell Lymphoid Malignancies. U.S.National Institutes of Health.
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ClinicalTrials.gov (NCT02851589) Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
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ClinicalTrials.gov (NCT00924326) CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma
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17 |
ClinicalTrials.gov (NCT02081937) CART-19 Immunotherapy in Mantle Cell Lymphoma
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18 |
ClinicalTrials.gov (NCT03185494) Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22
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19 |
ClinicalTrials.gov (NCT01735604) Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy
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20 |
ClinicalTrials.gov (NCT01865617) Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia
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21 |
ClinicalTrials.gov (NCT01475058) CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant
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22 |
ClinicalTrials.gov (NCT03676504) Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR
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23 |
ClinicalTrials.gov (NCT02652910) Memory-enriched CAR-T Cells Immunotherapy for B Cell Lymphoma
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24 |
ClinicalTrials.gov (NCT03277729) A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas
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25 |
ClinicalTrials.gov (NCT04419389) APR-246 in Combination With Ibrutinib or Venetoclax-R in Subjects With TP53-Mutant R/R Non Hodgkin Lymphomas (NHL) (R/R). U.S. National Institutes of Health.
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26 |
ClinicalTrials.gov (NCT03625037) GEN3013 Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma. U.S. National Institutes of Health.
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27 |
ClinicalTrials.gov (NCT03436771) Long-term Follow-up Study for Patients Previously Treated With a Juno CAR T-Cell Product
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28 |
ClinicalTrials.gov (NCT02819583) CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
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29 |
ClinicalTrials.gov (NCT01435720) Safety and Tolerability Study of SNS01-T in Relapsed or Refractory B Cell Malignancies (Multiple Myeloma, B Cell Lymphoma, or Plasma Cell Leukemia (PCL). U.S. National Institutes of Health.
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30 |
ClinicalTrials.gov (NCT03571828) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, or Follicular Lymphoma. U.S. National Institutes of Health.
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31 |
ClinicalTrials.gov (NCT02721407) Anti-CD22 CAR-T Therapy for CD19-refractory or Resistant Lymphoma Patients
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32 |
ClinicalTrials.gov (NCT02706392) Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
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33 |
ClinicalTrials.gov (NCT03097770) Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20
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34 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2082).
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The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
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Update on lymphoproliferative disorders of the gastrointestinal tract: disease spectrum from indolent lymphoproliferations to aggressive lymphomas.Virchows Arch. 2020 May;476(5):667-681. doi: 10.1007/s00428-019-02704-8. Epub 2019 Nov 26.
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A phase 1 trial of ibrutinib plus palbociclib in previously treated mantle cell lymphoma.Blood. 2019 Mar 14;133(11):1201-1204. doi: 10.1182/blood-2018-11-886457. Epub 2019 Jan 28.
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Expression and Function of Histone Deacetylase 10 (HDAC10) in B Cell Malignancies.Methods Mol Biol. 2016;1436:129-45. doi: 10.1007/978-1-4939-3667-0_10.
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Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma.Oncogene. 2020 Feb;39(9):2009-2023. doi: 10.1038/s41388-019-1122-x. Epub 2019 Nov 26.
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DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas.Mol Cancer Ther. 2019 Jul;18(7):1255-1264. doi: 10.1158/1535-7163.MCT-18-0919. Epub 2019 May 7.
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High expression of the inhibitory receptor BTLA in T-follicular helper cells and in B-cell small lymphocytic lymphoma/chronic lymphocytic leukemia.Am J Clin Pathol. 2009 Oct;132(4):589-96. doi: 10.1309/AJCPPHKGYYGGL39C.
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Differential and tumor-specific expression of CD160 in B-cell malignancies.Blood. 2011 Aug 25;118(8):2174-83. doi: 10.1182/blood-2011-02-334326. Epub 2011 Jun 28.
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Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.Am J Hematol. 2012 Apr;87(4):361-7. doi: 10.1002/ajh.23115. Epub 2012 Feb 28.
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Kinematic effects of repeated turns while running.Eur J Sport Sci. 2019 Sep;19(8):1072-1081. doi: 10.1080/17461391.2019.1578416. Epub 2019 Mar 5.
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Phosphatidylinositol 3-kinase blockade increases genomic instability in B cells.Nature. 2017 Feb 23;542(7642):489-493. doi: 10.1038/nature21406. Epub 2017 Feb 15.
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Targeting of BMI-1 expression by the novel small molecule PTC596 in mantle cell lymphoma.Oncotarget. 2018 Jun 19;9(47):28547-28560. doi: 10.18632/oncotarget.25558. eCollection 2018 Jun 19.
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An in-depth evaluation of acalabrutinib for the treatment of mantle-cell lymphoma.Expert Opin Pharmacother. 2020 Jan;21(1):29-38. doi: 10.1080/14656566.2019.1689959. Epub 2019 Nov 18.
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Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma.Int J Cancer. 2007 Apr 15;120(8):1669-77. doi: 10.1002/ijc.22404.
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Paclitaxel synergizes with exposure time adjusted CD22-targeting immunotoxins against B-cell malignancies.Oncotarget. 2017 May 9;8(19):30644-30655. doi: 10.18632/oncotarget.16141.
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MicroRNA-506 inhibits the proliferation and invasion of mantle cell lymphoma cells by targeting B7H3.Biochem Biophys Res Commun. 2019 Jan 22;508(4):1067-1073. doi: 10.1016/j.bbrc.2018.12.055. Epub 2018 Dec 12.
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Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma.Blood. 2010 Aug 19;116(7):1025-34. doi: 10.1182/blood-2009-12-257485. Epub 2010 Apr 28.
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Phase 2 Study of Daratumumab in Relapsed/Refractory Mantle-Cell Lymphoma, Diffuse Large B-Cell Lymphoma, and Follicular Lymphoma.Clin Lymphoma Myeloma Leuk. 2019 May;19(5):275-284. doi: 10.1016/j.clml.2018.12.013. Epub 2019 Jan 2.
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Polymorphism in the CD5 gene promoter in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.Am J Clin Pathol. 2005 May;123(5):646-50.
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ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.Exp Hematol. 2015 Sep;43(9):770-4.e2. doi: 10.1016/j.exphem.2015.04.008. Epub 2015 Apr 29.
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Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19.Clin Cancer Res. 2019 Dec 1;25(23):7046-7057. doi: 10.1158/1078-0432.CCR-19-1337. Epub 2019 Aug 22.
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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma.Br J Cancer. 2019 Jun;120(12):1137-1146. doi: 10.1038/s41416-019-0471-0. Epub 2019 May 15.
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Discovery and characterization of a novel CCND1/MRCK gene fusion in mantle cell lymphoma.J Hematol Oncol. 2016 Mar 29;9:30. doi: 10.1186/s13045-016-0260-7.
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Synergistic Cytotoxicity of Lenalidomide and Dexamethasone in Mantle Cell Lymphoma via Cereblon-dependent Targeting of the IL-6/STAT3/PI3K Axis.EBioMedicine. 2017 Jun;20:70-78. doi: 10.1016/j.ebiom.2017.04.037. Epub 2017 May 10.
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The mTOR kinase inhibitor everolimus synergistically enhances the anti-tumor effect of the Bruton's tyrosine kinase (BTK) inhibitor PLS-123 on Mantle cell lymphoma.Int J Cancer. 2018 Jan 1;142(1):202-213. doi: 10.1002/ijc.31044. Epub 2017 Oct 16.
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Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.Mol Cancer. 2014 Jun 27;13:159. doi: 10.1186/1476-4598-13-159.
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Iron chelation and 2-oxoglutarate-dependent dioxygenase inhibition suppress mantle cell lymphoma's cyclin D1.J Cell Mol Med. 2019 Nov;23(11):7785-7795. doi: 10.1111/jcmm.14655. Epub 2019 Sep 13.
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Novel treatment for mantle cell lymphoma including therapy-resistant tumor by NF-B and mTOR dual-targeting approach.Mol Cancer Ther. 2013 Oct;12(10):2006-17. doi: 10.1158/1535-7163.MCT-13-0239. Epub 2013 Aug 20.
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Targeting EZH1/2 induces cell cycle arrest and inhibits cell proliferation through reactivation of p57(CDKN1C) and TP53INP1 in mantle cell lymphoma.Cancer Biol Med. 2019 Aug;16(3):530-541. doi: 10.20892/j.issn.2095-3941.2018.0380.
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SOX11-negative Mantle Cell Lymphoma: Clinicopathologic and Prognostic Features of 75 Patients.Am J Surg Pathol. 2019 May;43(5):710-716. doi: 10.1097/PAS.0000000000001233.
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Unbalanced expression of licensing DNA replication factors occurs in a subset of mantle cell lymphomas with genomic instability.Int J Cancer. 2006 Dec 15;119(12):2768-74. doi: 10.1002/ijc.22146.
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Disruption of the PRKCD-FBXO25-HAX-1 axis attenuates the apoptotic response and drives lymphomagenesis.Nat Med. 2014 Dec;20(12):1401-9. doi: 10.1038/nm.3740. Epub 2014 Nov 24.
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Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lymphoma cells.Leukemia. 2019 Jul;33(7):1675-1686. doi: 10.1038/s41375-018-0355-y. Epub 2019 Jan 21.
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A high mutation rate of immunoglobulin heavy chain variable region gene associates with a poor survival and chemotherapy response of mantle cell lymphoma patients.Medicine (Baltimore). 2019 May;98(22):e15811. doi: 10.1097/MD.0000000000015811.
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Lymphotoxin beta expression is high in chronic lymphocytic leukemia but low in small lymphocytic lymphoma: a quantitative real-time reverse transcriptase polymerase chain reaction analysis.Haematologica. 2003 Jun;88(6):654-8.
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B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma.Blood. 2017 Jan 19;129(3):333-346. doi: 10.1182/blood-2016-05-718775. Epub 2016 Nov 18.
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Minichromosome maintenance protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma.Br J Cancer. 2005 Oct 17;93(8):939-45. doi: 10.1038/sj.bjc.6602795.
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Cyclin D1 transcriptional activation in MCL.Blood. 2014 Mar 27;123(13):1979-80. doi: 10.1182/blood-2014-02-553057.
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High expression of cyclic nucleotide phosphodiesterase 7B mRNA predicts poor prognosis in mantle cell lymphoma.Leuk Res. 2013 May;37(5):536-40. doi: 10.1016/j.leukres.2013.02.006. Epub 2013 Feb 28.
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Phosphoinositide-dependent protein kinase 1 is a potential novel therapeutic target in mantle cell lymphoma.Exp Hematol. 2018 Mar;59:72-81.e2. doi: 10.1016/j.exphem.2017.12.006. Epub 2017 Dec 26.
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Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.Blood. 2012 Oct 25;120(17):3491-500. doi: 10.1182/blood-2012-02-412643. Epub 2012 Sep 6.
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Mismatch repair gene expression in malignant lymphoproliferative disorders of B-cell origin.Leuk Lymphoma. 2002 Feb;43(2):393-9. doi: 10.1080/10428190290006215.
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Protein arginine methyltransferase 5 represses tumor suppressor miRNAs that down-regulate CYCLIN D1 and c-MYC expression in aggressive B-cell lymphoma.J Biol Chem. 2020 Jan 31;295(5):1165-1180. doi: 10.1074/jbc.RA119.008742. Epub 2019 Dec 10.
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Detection of t(12;14)(p13;q32) in a patient with IGH-CCND1 negative mantle cell lymphoma resembling ultra-high risk chronic lymphocytic leukemia.Int J Clin Exp Pathol. 2015 Jun 1;8(6):7494-8. eCollection 2015.
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Cutting Edge: ROR1/CD19 Receptor Complex Promotes Growth of Mantle Cell Lymphoma Cells Independently of the B Cell Receptor-BTK Signaling Pathway.J Immunol. 2019 Oct 15;203(8):2043-2048. doi: 10.4049/jimmunol.1801327. Epub 2019 Sep 18.
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Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line.Cancer Res. 2010 Aug 15;70(16):6587-97. doi: 10.1158/0008-5472.CAN-09-3578. Epub 2010 Jul 27.
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TCL1 expression predicts overall survival in patients with mantle cell lymphoma.Eur J Haematol. 2015 Dec;95(6):583-94. doi: 10.1111/ejh.12539. Epub 2015 Mar 16.
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Bax345/BLyS: a novel, completely human fusion protein targeting malignant B cells and delivering a unique mitochondrial toxin.Cancer Lett. 2012 Sep 28;322(2):159-68. doi: 10.1016/j.canlet.2012.02.029. Epub 2012 Mar 1.
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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.J Biol Chem. 2016 Nov 18;291(47):24628-24640. doi: 10.1074/jbc.M116.738567. Epub 2016 Sep 28.
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XPO1 Inhibitor Selinexor Overcomes Intrinsic Ibrutinib Resistance in Mantle Cell Lymphoma via Nuclear Retention of IB.Mol Cancer Ther. 2018 Dec;17(12):2564-2574. doi: 10.1158/1535-7163.MCT-17-0789-ATR.
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Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling.Clin Cancer Res. 2008 Nov 1;14(21):6907-15. doi: 10.1158/1078-0432.CCR-08-0388.
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High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.Leukemia. 2003 Sep;17(9):1880-90. doi: 10.1038/sj.leu.2403057.
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Ibrutinib in CLL/SLL: From bench to bedside (Review).Oncol Rep. 2019 Dec;42(6):2213-2227. doi: 10.3892/or.2019.7364. Epub 2019 Oct 10.
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Establishment and Characteristics of a Novel Mantle Cell Lymphoma-derived Cell Line and a Bendamustine-resistant Subline.Cancer Genomics Proteomics. 2018 May-Jun;15(3):213-223. doi: 10.21873/cgp.20080.
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Genetic analysis of splenic lymphoma with villous lymphocytes: a Groupe Franais d'Hmatologie Cellulaire (GFHC) study.Br J Haematol. 1998 Jun;101(4):712-21. doi: 10.1046/j.1365-2141.1998.00764.x.
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Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate (177)Lu-NNV003.Eur J Nucl Med Mol Imaging. 2019 Oct;46(11):2311-2321. doi: 10.1007/s00259-019-04417-1. Epub 2019 Jul 15.
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Evaluation of CD307a expression patterns during normal B-cell maturation and in B-cell malignancies by flow cytometry.Cytometry B Clin Cytom. 2018 Jul;94(4):588-595. doi: 10.1002/cyto.b.21631. Epub 2018 Mar 9.
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Comparison of Myocyte Enhancer Factor 2B Versus Other Germinal Center-associated Antigens in the Differential Diagnosis of B-Cell Non-Hodgkin Lymphomas.Am J Surg Pathol. 2018 Mar;42(3):342-350. doi: 10.1097/PAS.0000000000001015.
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Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas. Haematologica. 2007 Apr;92(4):460-8. doi: 10.3324/haematol.10337.
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Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia.Leukemia. 2009 Nov;23(11):2018-26. doi: 10.1038/leu.2009.144. Epub 2009 Jul 30.
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MS4A4A: a novel cell surface marker for M2 macrophages and plasma cells.Immunol Cell Biol. 2017 Aug;95(7):611-619. doi: 10.1038/icb.2017.18. Epub 2017 Mar 17.
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A proline/arginine-rich end leucine-rich repeat protein (PRELP) variant is uniquely expressed in chronic lymphocytic leukemia cells.PLoS One. 2013 Jun 24;8(6):e67601. doi: 10.1371/journal.pone.0067601. Print 2013.
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The interaction between ATRIP and MCM complex is essential for ATRIP chromatin loading and its phosphorylation in mantle cell lymphoma cells.Pharmazie. 2017 Nov 1;72(11):670-673. doi: 10.1691/ph.2017.7676.
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Bifurcated BACH2 control coordinates mantle cell lymphoma survival and dispersal during hypoxia.Blood. 2017 Aug 10;130(6):763-776. doi: 10.1182/blood-2017-02-767293. Epub 2017 Jun 7.
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Proapoptotic protein BIM as a novel prognostic marker in mantle cell lymphoma.Hum Pathol. 2019 Nov;93:54-64. doi: 10.1016/j.humpath.2019.08.008. Epub 2019 Aug 16.
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Pleiotropic Action of Novel Bruton's Tyrosine Kinase Inhibitor BGB-3111 in Mantle Cell Lymphoma.Mol Cancer Ther. 2019 Feb;18(2):267-277. doi: 10.1158/1535-7163.MCT-18-0478. Epub 2018 Nov 9.
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Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK.Cell Death Dis. 2014 Aug 28;5(8):e1389. doi: 10.1038/cddis.2014.346.
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Expression of D-type cyclins in mantle cell and diffuse large B-cell lymphomas.Oncol Rep. 2016 May;35(5):2673-80. doi: 10.3892/or.2016.4658. Epub 2016 Mar 7.
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Rearrangement of CCND1 (BCL1/PRAD1) 3' untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias.Blood. 1994 Jun 15;83(12):3689-96.
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SOX11 augments BCR signaling to drive MCL-like tumor development.Blood. 2018 May 17;131(20):2247-2255. doi: 10.1182/blood-2018-02-832535. Epub 2018 Apr 3.
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Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes.Clin Cancer Res. 2014 Jan 15;20(2):393-403. doi: 10.1158/1078-0432.CCR-13-1569. Epub 2013 Oct 31.
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Molecular hematology. Qualitative to quantitative techniques.Saudi Med J. 2005 Oct;26(10):1516-22.
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Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray.Blood. 2001 Aug 1;98(3):787-94. doi: 10.1182/blood.v98.3.787.
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Modified VR-CAP, Alternating With Rituximab and High-dose Cytarabine: An Effective Pre-transplant Induction Regimen for Mantle Cell Lymphoma.Clin Lymphoma Myeloma Leuk. 2019 Jan;19(1):48-52. doi: 10.1016/j.clml.2018.10.006. Epub 2018 Oct 17.
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Molecular signatures for CCN1, p21 and p27 in progressive mantle cell lymphoma.J Cell Commun Signal. 2019 Sep;13(3):421-434. doi: 10.1007/s12079-018-0494-y. Epub 2018 Nov 21.
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Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma.Blood. 2008 Dec 15;112(13):5171-9. doi: 10.1182/blood-2008-02-139212. Epub 2008 Sep 11.
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Integrated analysis of 10 lymphoma datasets identifies E2F8 as a key regulator in Burkitt's lymphoma and mantle cell lymphoma.Am J Transl Res. 2019 Jul 15;11(7):4382-4396. eCollection 2019.
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Mantle cell lymphoma: 2012 update on diagnosis, risk-stratification, and clinical management.Am J Hematol. 2012 Jun;87(6):604-9. doi: 10.1002/ajh.23176.
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FBXO10 deficiency and BTK activation upregulate BCL2 expression in mantle cell lymphoma.Oncogene. 2016 Dec 1;35(48):6223-6234. doi: 10.1038/onc.2016.155. Epub 2016 May 9.
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Mantle cell lymphoma-variant Richter syndrome: Detailed molecular-cytogenetic and backtracking analysis reveals slow evolution of a pre-MCL clone in parallel with CLL over several years.Int J Cancer. 2016 Nov 15;139(10):2252-60. doi: 10.1002/ijc.30263. Epub 2016 Aug 2.
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Oncogenic deregulation of NKL homeobox gene MSX1 in mantle cell lymphoma.Leuk Lymphoma. 2014 Aug;55(8):1893-903. doi: 10.3109/10428194.2013.864762. Epub 2014 Feb 17.
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Expression of GNAZ, encoding the G(z) protein, predicts survival in mantle cell lymphoma.Br J Haematol. 2019 May;185(4):708-712. doi: 10.1111/bjh.15810. Epub 2019 Feb 20.
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Frontline bortezomib, rituximab, cyclophosphamide, doxorubicin, and prednisone (VR-CAP) versus rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in transplantation-ineligible patients with newly diagnosed mantle cell lymphoma: final overall survival results of a randomised, open-label, phase 3 study.Lancet Oncol. 2018 Nov;19(11):1449-1458. doi: 10.1016/S1470-2045(18)30685-5. Epub 2018 Oct 19.
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SOX11 and HIG-2 are cross-regulated and affect growth in mantle cell lymphoma.Leuk Lymphoma. 2016 Aug;57(8):1883-92. doi: 10.3109/10428194.2015.1121257. Epub 2016 Jan 12.
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Ibrutinib increases the risk of hypertension and atrial fibrillation: Systematic review and meta-analysis.PLoS One. 2019 Feb 20;14(2):e0211228. doi: 10.1371/journal.pone.0211228. eCollection 2019.
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Mantle cell lymphoma cell lines show no evident immunoglobulin heavy chain stereotypy but frequent light chain stereotypy.Leuk Lymphoma. 2013 Aug;54(8):1747-55. doi: 10.3109/10428194.2012.758843. Epub 2013 Jan 23.
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The lipid raft protein NTAL participates in AKT signaling in mantle cell lymphoma.Leuk Lymphoma. 2019 Nov;60(11):2658-2668. doi: 10.1080/10428194.2019.1607326. Epub 2019 May 7.
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Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma.Cytometry B Clin Cytom. 2018 Jan;94(1):148-150. doi: 10.1002/cyto.b.21512. Epub 2017 Feb 24.
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GeneChip analyses point to novel pathogenetic mechanisms in mantle cell lymphoma.Br J Haematol. 2009 Feb;144(3):317-31. doi: 10.1111/j.1365-2141.2008.07443.x. Epub 2008 Nov 7.
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Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling.Blood. 2010 Aug 12;116(6):953-61. doi: 10.1182/blood-2010-01-263806. Epub 2010 Apr 26.
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