General Information of Drug (ID: DMDINFS)

Drug Name
Sanguinarine Drug Info
Synonyms
SANGUINARINE; 2447-54-3; Pseudochelerythrine; Sanguinarin; sangvinarin; Veadent; Sanguiritrin; SANGUINARIUM; Dimethylenedioxy benzphenanthridine; UNII-AV9VK043SS; C20H14NO4; EINECS 219-503-3; Benzophenanthridine alkaloid; BRN 3915507; AV9VK043SS; CHEBI:17183; NCGC00015959-03; CAS-2447-54-3; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium, 13-methyl-; DSSTox_RID_80748; DSSTox_CID_25204; DSSTox_GSID_45204; 13-Methyl[1,3]benzodioxolo[5,6-C][1,3]dioxolo[4,5-I]phenanthridin-13-Ium; Sangrovit; y-Chelerythrine; SR-01000075650
Indication
Disease Entry ICD 11 Status REF
Dental plaque DA08.4 Approved [1]
Cross-matching ID
PubChem CID
5154
ChEBI ID
CHEBI:17183
CAS Number
CAS 2447-54-3
TTD Drug ID
DMDINFS
VARIDT Drug ID
DR00919

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Digoxin DMQCTIH Arrhythmia BC9Z Approved [9]
Digitoxin DMWVIGP Arrhythmia BC9Z Approved [10]
Rostafuroxin DMKQXDB Hypertension BA00-BA04 Phase 2 [11]
PBI-05204 DM05WIU Pancreatic cancer 2C10 Phase 2 [12]
RX108 DM4XETK Solid tumour/cancer 2A00-2F9Z Phase 1 [13]
Istaroxime DMWN09H Cardiac disease BA00-BE2Z Discontinued in Phase 2 [14]
Cordil DMQESM7 Heart arrhythmia BC65 Terminated [15]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [16]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [17]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [18]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [19]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [20]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Ethacrynic acid DM60QMR Edema MG29 Approved [22]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [23]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [24]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [25]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [17]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [28]
Estrone DM5T6US Acne vulgaris ED80 Approved [29]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [30]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [31]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [32]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [33]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [34]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [35]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [36]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [39]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [40]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [41]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [42]
Quercetin DM3NC4M Obesity 5B81 Approved [43]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [44]
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Drug(s) Affected By Claudin-5 (CLDN5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [45]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [46]
Glycine DMIOZ29 Allergic rhinitis CA08.0 Approved [47]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [48]
Urethane DM7NSI0 N. A. N. A. Phase 4 [49]
CS-600G DM1PV4Y N. A. N. A. Phase 3 [50]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [51]
LY294002 DMY1AFS Neuroblastoma 2D11.2 Phase 1 [52]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [47]
JWH-133 DM1DEYU Discovery agent N.A. Investigative [53]
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Drug(s) Affected By Claudin-4 (CLDN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [55]
Selenium DM25CGV N. A. N. A. Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Panobinostat DM58WKG Chronic graft versus host disease Approved [60]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [61]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [62]
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Drug(s) Affected By Claudin-3 (CLDN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [63]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [46]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [66]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [67]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [63]
Arsenic DMTL2Y1 N. A. N. A. Approved [68]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [69]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [70]
Suramin DMTOUY9 African trypanosomiasis 1F51 Phase 1 [71]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [73]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [74]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [75]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [76]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [79]
Quercetin DM3NC4M Obesity 5B81 Approved [80]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [82]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [83]
Leflunomide DMR8ONJ Arthritis FA20 Approved [84]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [85]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [86]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Selenium DM25CGV N. A. N. A. Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [93]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [94]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [95]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [96]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [97]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [98]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [99]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [100]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [101]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Verapamil DMA7PEW Angina pectoris BA40 Approved [103]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [104]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [105]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [77]
Gefitinib DM15F0X Colon adenocarcinoma Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Selenium DM25CGV N. A. N. A. Approved [88]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [110]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [111]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [113]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [114]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [117]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [23]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [123]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [124]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [105]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [125]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [126]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [127]
Gefitinib DM15F0X Colon adenocarcinoma Approved [128]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [129]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [131]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [123]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [132]
Paclitaxel DMLB81S Breast carcinoma Approved [133]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [134]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [101]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [105]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [125]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-1 (CASP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Gefitinib DM15F0X Colon adenocarcinoma Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [138]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [144]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [145]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [146]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [147]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [148]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [149]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [153]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [154]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Gefitinib DM15F0X Colon adenocarcinoma Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [157]
Quercetin DM3NC4M Obesity 5B81 Approved [158]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [159]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [160]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [157]
Ethacrynic acid DM60QMR Edema MG29 Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [157]
Methotrexate DM2TEOL Anterior urethra cancer Approved [163]
Quercetin DM3NC4M Obesity 5B81 Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [165]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Sorbitol DMAN0DE Constipation DD91.1 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [168]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
Selenium DM25CGV N. A. N. A. Approved [56]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [170]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [171]
Methotrexate DM2TEOL Anterior urethra cancer Approved [112]
Quercetin DM3NC4M Obesity 5B81 Approved [172]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [174]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-5 (CASP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Menthol DMG2KW7 Back pain ME84.Z Approved [175]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Paclitaxel DMLB81S Breast carcinoma Approved [177]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [178]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [179]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
9-hydroxyoctadecadienoic acid DM0FWNJ Discovery agent N.A. Investigative [180]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [179]
CHLORANIL DMCHGF1 Discovery agent N.A. Investigative [181]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [182]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [183]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [104]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [184]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [185]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [186]
Meloxicam DM2AR7L Arthritis FA20 Approved [187]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [188]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [189]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [190]
Quercetin DM3NC4M Obesity 5B81 Approved [158]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [191]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [192]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [193]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [194]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [195]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-2 (CLDN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [74]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [196]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [197]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [198]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [197]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [200]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [201]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [202]
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Drug(s) Affected By Lymphotoxin-beta (LTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [203]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [204]
Leflunomide DMR8ONJ Arthritis FA20 Approved [84]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [205]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [206]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [208]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [97]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [153]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Verapamil DMA7PEW Angina pectoris BA40 Approved [103]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [169]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [184]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [209]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Meloxicam DM2AR7L Arthritis FA20 Approved [210]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [211]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [212]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [213]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [214]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [135]
Gefitinib DM15F0X Colon adenocarcinoma Approved [215]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [216]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [56]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [218]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [219]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [64]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [220]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [178]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [223]
Clozapine DMFC71L Schizophrenia 6A20 Approved [224]
Menthol DMG2KW7 Back pain ME84.Z Approved [175]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [225]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [226]
Fenretinide DMRD5SP Macular degeneration 9B78.3 Phase 3 [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [4]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [219]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Menthol DMG2KW7 Back pain ME84.Z Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [178]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [228]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [229]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [230]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [231]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [232]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sodium/potassium-transporting ATPase (SPT ATPase) TTQ38E9 AT1A1_HUMAN; AT1A2_HUMAN; AT1A3_HUMAN; AT1B1_HUMAN; AT1B2_HUMAN; AT1B3_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [3]
Apoptosis facilitator Bcl-2-like protein 14 (BCL2L14) OT87E7HW B2L14_HUMAN Gene/Protein Processing [4]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Protein Interaction/Cellular Processes [6]
Caspase-1 (CASP1) OTZ3YQFU CASP1_HUMAN Gene/Protein Processing [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [7]
Caspase-5 (CASP5) OT0F2THD CASP5_HUMAN Gene/Protein Processing [4]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [7]

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