General Information of Drug (ID: DMTUC9E)

Drug Name
PMID28870136-Compound-49 Drug Info
Cross-matching ID
PubChem CID
4740
ChEBI ID
CHEBI:7986
CAS Number
CAS 6493-05-6
TTD Drug ID
DMTUC9E
ACDINA Drug ID
D00517

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Approved Drug(s)
Drug(s) Targeting Ecto-5'-nucleotidase (CD73)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TJ004309 DMFB54Y Ovarian cancer 2C73 Phase 2 [8]
GS-1423 DMS25DL Solid tumour/cancer 2A00-2F9Z Phase 1 [9]
Oleclumab DMLVNWO Solid tumour/cancer 2A00-2F9Z Phase 1 [10]
AB680 DMGONUE Pancreatic cancer 2C10 Phase 1 [11]
TJ4309 DMM3U2Q Solid tumour/cancer 2A00-2F9Z Phase 1 [12]
CPI-006 DMJSFTX Advanced cancer 2A00-2F9Z Phase 1 [13]
LY3475070 DMZLIWX Solid tumour/cancer 2A00-2F9Z Phase 1 [14]
NZV930 DMWN2FP Solid tumour/cancer 2A00-2F9Z Phase 1 [15]
PMID28870136-Compound-57 DME3HLC N. A. N. A. Patented [1]
PMID28870136-Compound-46 DM4FD7C N. A. N. A. Patented [1]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [16]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [16]
Capsaicin DMGMF6V Back pain ME84.Z Approved [17]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [18]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [19]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [20]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [21]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [22]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [23]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [28]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [31]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [33]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [34]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [37]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [38]
Selenium DM25CGV N. A. N. A. Approved [39]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [34]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [40]
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [40]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [45]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [50]
Ethacrynic acid DM60QMR Edema MG29 Approved [51]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Selenium DM25CGV N. A. N. A. Approved [53]
Methotrexate DM2TEOL Anterior urethra cancer Approved [54]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [55]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [57]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [58]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [59]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [60]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [59]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [62]
Verapamil DMA7PEW Angina pectoris BA40 Approved [63]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [64]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [63]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [65]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [70]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [71]
Fructose DM43AN2 Vomiting MD90 Approved [23]
Ketoprofen DMRKXPT Bursitis Approved [23]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [72]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [73]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [74]
Gefitinib DM15F0X Colon adenocarcinoma Approved [75]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [78]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [79]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [80]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [81]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [83]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [84]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Folic Acid DMEMBJC Colorectal carcinoma Approved [85]
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Drug(s) Affected By C-reactive protein (CRP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [23]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [86]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [87]
Quercetin DM3NC4M Obesity 5B81 Approved [88]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [89]
Acalabrutinib DM7GCVW leukaemia 2A60-2B33 Approved [90]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [91]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [92]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [93]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
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Drug(s) Affected By Integrin beta-2 (ITGB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [95]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [96]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [97]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [61]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [98]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [100]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [101]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [102]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [103]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [104]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [105]
Cepharanthine DM9Y5JB N. A. N. A. Approved [106]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [107]
Clozapine DMFC71L Schizophrenia 6A20 Approved [108]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [109]
Trifluoperazine DMKBYWI Anxiety Approved [110]
Olanzapine DMPFN6Y Bipolar depression Approved [108]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [111]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [113]
Verapamil DMA7PEW Angina pectoris BA40 Approved [114]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Selenium DM25CGV N. A. N. A. Approved [117]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [118]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [119]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Gefitinib DM15F0X Colon adenocarcinoma Approved [121]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [122]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [123]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [124]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [125]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [124]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [126]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [127]
Methotrexate DM2TEOL Anterior urethra cancer Approved [128]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [129]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [130]
Gefitinib DM15F0X Colon adenocarcinoma Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [132]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [133]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [118]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [136]
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Drug(s) Affected By Perforin-1 (PRF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Testosterone enanthate DMB6871 N. A. N. A. Approved [138]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Menthol DMG2KW7 Back pain ME84.Z Approved [139]
Bortezomib DMNO38U Leukemia Approved [140]
Arsenic DMTL2Y1 N. A. N. A. Approved [141]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [142]
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [23]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [143]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [144]
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Drug(s) Affected By Natriuretic peptides B (NPPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [145]
Methotrexate DM2TEOL Anterior urethra cancer Approved [41]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [146]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [147]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [148]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [56]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [150]
Ethanol DMDRQZU Chronic pain MG30 Approved [151]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [112]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [64]
Gefitinib DM15F0X Colon adenocarcinoma Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [154]
Methotrexate DM2TEOL Anterior urethra cancer Approved [155]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [157]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [158]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [159]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [160]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [123]
Methotrexate DM2TEOL Anterior urethra cancer Approved [161]
Epinephrine DM3KJBC Acute asthma CA23 Approved [162]
Quercetin DM3NC4M Obesity 5B81 Approved [163]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [164]
Fructose DM43AN2 Vomiting MD90 Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [166]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Diazepam DM08E9O Alcohol withdrawal Approved [167]
Quercetin DM3NC4M Obesity 5B81 Approved [168]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [89]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [169]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [170]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [170]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [171]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [172]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [173]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [174]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [175]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [176]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [177]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [178]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [179]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [180]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [181]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [182]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Gefitinib DM15F0X Colon adenocarcinoma Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [116]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [184]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [185]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [186]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [184]
Ethacrynic acid DM60QMR Edema MG29 Approved [187]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [184]
Methotrexate DM2TEOL Anterior urethra cancer Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [190]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [184]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [191]
Sorbitol DMAN0DE Constipation DD91.1 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [33]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [37]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [42]
Selenium DM25CGV N. A. N. A. Approved [53]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [193]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [196]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [197]
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Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [198]
Gefitinib DM15F0X Colon adenocarcinoma Approved [121]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [199]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [200]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [201]
Methotrexate DM2TEOL Anterior urethra cancer Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [25]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [202]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [203]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [204]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [205]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [123]
Selenium DM25CGV N. A. N. A. Approved [53]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [206]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [207]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [47]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [195]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [73]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [42]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [208]
Methotrexate DM2TEOL Anterior urethra cancer Approved [44]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [209]
Quercetin DM3NC4M Obesity 5B81 Approved [163]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [210]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [42]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [211]
Ethacrynic acid DM60QMR Edema MG29 Approved [51]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ecto-5'-nucleotidase (CD73) TTK0O6Y 5NTD_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [2]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Protein Interaction/Cellular Processes [4]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Gene/Protein Processing [5]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Gene/Protein Processing [3]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [3]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Protein Interaction/Cellular Processes [3]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [6]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Gene/Protein Processing [3]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Gene/Protein Processing [7]

References

1 Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304.
2 Nuclear factor-B signaling inhibitors revert multidrug-resistance in breast cancer cells. Chem Biol Interact. 2021 May 1;340:109450. doi: 10.1016/j.cbi.2021.109450. Epub 2021 Mar 26.
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4 Effect of pentoxifylline in addition to losartan on proteinuria and GFR in CKD: a 12-month randomized trial. Am J Kidney Dis. 2008 Sep;52(3):464-74. doi: 10.1053/j.ajkd.2008.05.012. Epub 2008 Jul 9.
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