Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6AN32)

Drug Name
Trovafloxacin Drug Info
Synonyms
TVFX; Trovan; Fluorinated quinolone; Trovafloxacin [INN]; CP 99219; CP99219; CP 99,219; CP-99219;Trovafloxacin (INN); Trovan (TN); Trovan (oral); Turvel (TN); CP-99,219; (1alpha,5alpha,6alpha)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 7-((1R,5S)-6-Amino-3-aza-bicyclo[3.1.0]hex-3-yl)-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid; 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid; 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid; 7-[(1r,5s)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Acute gonococcal cervicitis Approved [1]
Bacterial infection 1A00-1C4Z Approved [2]
Endomyometritis Approved [1]
Mycoplasma pneumoniae pneumonia Approved [1]
Staphylococcal pneumonia Approved [1]
Urinary tract infection GC08 Approved [1]
Pneumonia caused by chlamydia Investigative [1]
Therapeutic Class
Antiinfective Agents
Cross-matching ID
PubChem CID
62959
ChEBI ID
CHEBI:9763
CAS Number
CAS 147059-72-1
TTD Drug ID
DM6AN32

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Bacterial DNA gyrase (Bact gyrase)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Grepafloxacin DMGLX0T Chronic bronchitis CA20.1 Approved [8]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [3]
Levofloxacin DMS60RB Acute maxillary sinusitis Approved [3]
Gatifloxacin DMSL679 Acute gonococcal cervicitis Approved [3]
Norfloxacin DMIZ6W2 Acute gonococcal cervicitis Approved [3]
Ozenoxacin DM6KZMG Impetigo 1B72 Approved [9]
Sparfloxacin DMB4HCT Bacterial infection 1A00-1C4Z Approved [3]
Gemifloxacin DMHT34O Bacterial infection 1A00-1C4Z Approved [3]
Besifloxacin DMPHXMI Ocular inflammation 9C61.24 Approved [10]
Finafloxacin DMZEONG Urinary tract infection GC08 Approved [11]
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Drug(s) Affected By Aromatase (CYP19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [12]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [13]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [14]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [15]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [14]
Methotrexate DM2TEOL Anterior urethra cancer Approved [16]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [17]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Fluoxetine DM3PD2C Bipolar depression Approved [14]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3 beta 2 (MAP1LC3B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [20]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [25]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [26]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [27]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [28]
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Drug(s) Affected By Ubiquitin-like protein ATG12 (ATG12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [29]
Selenium DM25CGV N. A. N. A. Approved [30]
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [33]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [34]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Artesunate DMR27C8 Infection of P. falciparum 1F40 Approved [36]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [37]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [38]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [39]
Gefitinib DM15F0X Colon adenocarcinoma Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [41]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [42]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [43]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [44]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [43]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [45]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
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Drug(s) Affected By DNA topoisomerase 2-alpha (TOP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [48]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [49]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [50]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [51]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [57]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [58]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Selenium DM25CGV N. A. N. A. Approved [30]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [60]
Etretinate DM2CZFA Keratosis ED56 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [64]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [53]
Quercetin DM3NC4M Obesity 5B81 Approved [65]
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Drug(s) Affected By Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [66]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [66]
Ethacrynic acid DM60QMR Edema MG29 Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [70]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [71]
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Drug(s) Affected By NF-kappa-B inhibitor alpha (NFKBIA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [72]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [75]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [77]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [78]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [79]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [81]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [82]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [84]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [85]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [86]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [87]
Gefitinib DM15F0X Colon adenocarcinoma Approved [88]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [89]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [90]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [91]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [82]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [92]
Paclitaxel DMLB81S Breast carcinoma Approved [93]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [94]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [81]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [72]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [84]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [85]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [95]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [96]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [97]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [98]
Gefitinib DM15F0X Colon adenocarcinoma Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [101]
Selenium DM25CGV N. A. N. A. Approved [30]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [102]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [103]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [105]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [107]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [110]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [111]
Methotrexate DM2TEOL Anterior urethra cancer Approved [52]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [112]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [113]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [50]
Gefitinib DM15F0X Colon adenocarcinoma Approved [114]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [115]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Etretinate DM2CZFA Keratosis ED56 Approved [116]
Prednisone DM2HG4X Acute asthma CA23 Approved [117]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [44]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [118]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [120]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [121]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [122]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [123]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [124]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [125]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [126]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [127]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [73]
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Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [128]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [129]
Gefitinib DM15F0X Colon adenocarcinoma Approved [130]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [76]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [133]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [134]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [131]
Ethacrynic acid DM60QMR Edema MG29 Approved [135]
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Drug(s) Affected By Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Clozapine DMFC71L Schizophrenia 6A20 Approved [139]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [139]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [140]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [141]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [28]
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Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [98]
Selenium DM25CGV N. A. N. A. Approved [30]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [142]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [143]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [80]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [144]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [56]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [145]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [146]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [73]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [147]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [42]
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [148]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [149]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [150]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [151]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [146]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [73]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [152]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [153]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [154]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [156]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [157]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
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Drug(s) Affected By Autophagy-related protein 9B (ATG9B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [159]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [160]
Arsenic DMTL2Y1 N. A. N. A. Approved [161]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [162]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [25]
Milchsaure DM462BT Pruritus EC90 Investigative [163]
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Drug(s) Affected By Autophagy-related protein 16-1 (ATG16L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [147]
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [165]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [141]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [166]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [167]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [147]
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Drug(s) Affected By Beclin 1-associated autophagy-related key regulator (ATG14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [169]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [166]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [170]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [26]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [171]
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Drug(s) Affected By Protein Atg16l2 (ATG16L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [172]
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [140]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [141]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [54]
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Drug(s) Affected By RB1-inducible coiled-coil protein 1 (RB1CC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [174]
Bortezomib DMNO38U Leukemia Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [176]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [177]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
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Drug(s) Affected By Cysteine protease ATG4A (ATG4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [164]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [179]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [25]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [26]
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Drug(s) Affected By Autophagy-related protein 2 homolog B (ATG2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [182]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [166]
Urethane DM7NSI0 N. A. N. A. Phase 4 [24]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [183]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Autophagy-related protein 101 (ATG101)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [184]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Arsenic DMTL2Y1 N. A. N. A. Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [185]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [26]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [186]
Milchsaure DM462BT Pruritus EC90 Investigative [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [188]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [187]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [187]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [189]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [190]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Methotrexate DM2TEOL Anterior urethra cancer Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [194]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [195]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [33]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [196]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [55]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [198]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [198]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [199]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [200]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [201]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Autophagy protein 5 (ATG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [32]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [204]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [205]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [164]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [207]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [208]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [209]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [210]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [211]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [22]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [208]
Capsaicin DMGMF6V Back pain ME84.Z Approved [212]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [213]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [214]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [35]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ubiquitin-like-conjugating enzyme ATG3 (ATG3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [215]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [138]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [216]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [208]
Gentamicin DMKINJO Bacteremia 1A73 Approved [215]
Artesunate DMR27C8 Infection of P. falciparum 1F40 Approved [36]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [217]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [218]
Fructose DM43AN2 Vomiting MD90 Approved [72]
Ketoprofen DMRKXPT Bursitis Approved [72]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [219]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [84]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [220]
Gefitinib DM15F0X Colon adenocarcinoma Approved [130]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [221]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [222]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial DNA gyrase (Bact gyrase) TTN6J5F GYRA_STAAU; GYRB_STAAU Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Gene/Protein Processing [4]
Autophagy protein 5 (ATG5) OT4T5SMS ATG5_HUMAN Gene/Protein Processing [5]
Autophagy-related protein 101 (ATG101) OTG8QUXY ATGA1_HUMAN Gene/Protein Processing [5]
Autophagy-related protein 16-1 (ATG16L1) OTEOYC5D A16L1_HUMAN Gene/Protein Processing [5]
Autophagy-related protein 2 homolog B (ATG2B) OT7FGFJ1 ATG2B_HUMAN Gene/Protein Processing [5]
Autophagy-related protein 9B (ATG9B) OTJMJZW8 ATG9B_HUMAN Gene/Protein Processing [5]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [6]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [6]
Beclin 1-associated autophagy-related key regulator (ATG14) OTPZDKI0 BAKOR_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [7]

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