Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMINRKW)

Drug Name
Clomipramine Drug Info
Synonyms
Chlomipramine; Chlorimipramine; Clomicalm; Clomipramina; Clomipraminum; Hydiphen; Monochlorimipramine; Anafranil base; G 34586; Anafranil (TN); Anafranil (free base); Clomipramina [INN-Spanish]; Clomipramine (INN); Clomipramine [INN:BAN]; Clomipraminum [INN-Latin]; 10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5H-dibenz(b,f)azepine; 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine; 3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine; 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine; 3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine; 3-Chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine; 3-Chloroimipramine; 3-chloro-10,11-dihydro-N,N-dimethyl-5H-Dibenz(b,f)azepine-5-propanamine; 5H-Dibenz(b,f)azepine, 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-(8CI)
Indication
Disease Entry ICD 11 Status REF
Depression 6A70-6A7Z Approved [1]
Obsessive compulsive disorder 6B20 Approved [2]
Therapeutic Class
Antidepressants
Cross-matching ID
PubChem CID
2801
ChEBI ID
CHEBI:47780
CAS Number
CAS 303-49-1
TTD Drug ID
DMINRKW
VARIDT Drug ID
DR00476
ACDINA Drug ID
D00139

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Serotonin transporter (SERT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [13]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [14]
Fluoxetine DM3PD2C Bipolar depression Approved [15]
Vortioxetine DM6F1PU Major depressive disorder 6A70.3 Approved [16]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [17]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [18]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [19]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [15]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [15]
Trazodone DMK1GBJ Depression 6A70-6A7Z Approved [15]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [20]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [22]
Folic Acid DMEMBJC Colorectal carcinoma Approved [23]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [22]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [25]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [26]
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Drug(s) Affected By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [28]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [29]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [31]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [32]
Capsaicin DMGMF6V Back pain ME84.Z Approved [33]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [34]
Quinidine DMLPICK N. A. N. A. Approved [35]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [36]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [38]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [39]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [40]
Capsaicin DMGMF6V Back pain ME84.Z Approved [33]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [34]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [41]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [34]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [38]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [12]
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Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [42]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [43]
Haloperidol DM96SE0 Delirium Approved [12]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [44]
Selenium DM25CGV N. A. N. A. Approved [45]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [9]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [46]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
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Drug(s) Affected By Glutathione S-transferase P (GSTP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [50]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [51]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [52]
Chlorambucil DMRKE63 Chronic lymphocytic leukaemia 2A82.0 Approved [52]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [53]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Selenium DM25CGV N. A. N. A. Approved [56]
Etretinate DM2CZFA Keratosis ED56 Approved [57]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [58]
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Drug(s) Affected By Phytanoyl-CoA dioxygenase, peroxisomal (PHYH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [6]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [6]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [6]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [60]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [61]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [62]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [7]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
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Drug(s) Affected By Alpha-1-antichymotrypsin (SERPINA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [67]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [6]
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Drug(s) Affected By Serine protease hepsin (HPN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Selenium DM25CGV N. A. N. A. Approved [56]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [6]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [60]
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Drug(s) Affected By Fatty acid-binding protein, liver (FABP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [71]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [54]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [73]
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Drug(s) Affected By Lanosterol synthase (LSS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [74]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [76]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [6]
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Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [76]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [6]
Panobinostat DM58WKG Chronic graft versus host disease Approved [77]
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Drug(s) Affected By AP-1 complex subunit sigma-1A (AP1S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [7]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [81]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [63]
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Drug(s) Affected By Protein DEPP1 (DEPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [7]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [82]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [7]
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Drug(s) Affected By Asparagine synthetase (ASNS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [84]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [85]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [86]
Methotrexate DM2TEOL Anterior urethra cancer Approved [87]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [7]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [88]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
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Drug(s) Affected By Transgelin (TAGLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [89]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [63]
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Drug(s) Affected By Nuclear receptor subfamily 0 group B member 2 (NR0B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [92]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [74]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [7]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [95]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
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Drug(s) Affected By Lysophospholipase D GDPD3 (GDPD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [63]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [7]
Fluoxetine DM3PD2C Bipolar depression Approved [7]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [6]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [96]
Testosterone DM7HUNW Hot flushes GA30 Approved [97]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [97]
Haloperidol DM96SE0 Delirium Approved [7]
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Drug(s) Affected By Fibronectin type III domain-containing protein 4 (FNDC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [6]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [6]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [6]
Fluoxetine DM3PD2C Bipolar depression Approved [6]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [7]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [6]
Haloperidol DM96SE0 Delirium Approved [7]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Clozapine DMFC71L Schizophrenia 6A20 Approved [6]
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Drug(s) Affected By 5-hydroxytryptamine receptor 2C (HTR2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [5]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [5]
Fluoxetine DM3PD2C Bipolar depression Approved [5]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [97]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [60]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [103]
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Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [74]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [104]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [104]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [104]
Fructose DM43AN2 Vomiting MD90 Approved [105]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [104]
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Drug(s) Affected By Prolactin (PRL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [107]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [108]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [109]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [110]
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [111]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [112]
Aripiprazole DM3NUMH Bipolar I disorder Approved [113]
Fluoxetine DM3PD2C Bipolar depression Approved [114]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [115]
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Drug(s) Affected By Vitamin K-dependent protein C (PROC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desogestrel DM27U4Y Contraception QA21 Approved [116]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Testosterone DM7HUNW Hot flushes GA30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [118]
Testosterone enanthate DMB6871 N. A. N. A. Approved [119]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [98]
Clozapine DMFC71L Schizophrenia 6A20 Approved [120]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [76]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [121]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [62]
Gefitinib DM15F0X Colon adenocarcinoma Approved [123]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [124]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [125]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [126]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [127]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [126]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [128]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [129]
Methotrexate DM2TEOL Anterior urethra cancer Approved [130]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [132]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [133]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [134]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [135]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [136]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [137]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [139]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [142]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [143]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [144]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [8]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [8]
Methotrexate DM2TEOL Anterior urethra cancer Approved [145]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [146]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [147]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [149]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [150]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [104]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [151]
Fluoxetine DM3PD2C Bipolar depression Approved [104]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [153]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [154]
Estrone DM5T6US Acne vulgaris ED80 Approved [155]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [156]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [157]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [158]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [159]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent serotonin transporter (SLC6A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [161]
Fluoxetine DM3PD2C Bipolar depression Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [69]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [163]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [164]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [165]
Quercetin DM3NC4M Obesity 5B81 Approved [49]
Aripiprazole DM3NUMH Bipolar I disorder Approved [166]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [164]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [118]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Serotonin transporter (SERT) TT3ROYC SC6A4_HUMAN Inhibitor [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
5-hydroxytryptamine receptor 2C (HTR2C) OT6H8DE0 5HT2C_HUMAN Protein Interaction/Cellular Processes [5]
Alpha-1-antichymotrypsin (SERPINA3) OT9BP2S0 AACT_HUMAN Gene/Protein Processing [6]
AP-1 complex subunit sigma-1A (AP1S1) OTQ2H8DN AP1S1_HUMAN Gene/Protein Processing [6]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Gene/Protein Processing [7]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [8]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [8]
Catalase (CAT) OTHEBX9R CATA_HUMAN Gene/Protein Processing [9]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Gene/Protein Processing [10]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Regulation of Drug Effects [11]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Drug Response [12]

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