DDI Drug Name |
DDI Drug ID |
Severity |
Mechanism |
Comorbidity |
REF |
Remdesivir |
DMBFZ6L
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Remdesivir. |
1D6YCoronavirus Disease 2019 [1D6YCoronavirus Disease 2019]
|
[11] |
Methylene blue |
DMJAPE7
|
Major |
Increased risk of hyperpyrexia by the combination of Atomoxetine and Methylene blue. |
Acquired methaemoglobinaemia [3A93]
|
[12] |
Thioguanine |
DM7NKEV
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Thioguanine. |
Acute myeloid leukaemia [2A60]
|
[13] |
Ivosidenib |
DM8S6T7
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ivosidenib. |
Acute myeloid leukaemia [2A60]
|
[14] |
Midostaurin |
DMI6E0R
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Midostaurin. |
Acute myeloid leukaemia [2A60]
|
[15] |
Idarubicin |
DMM0XGL
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Idarubicin. |
Acute myeloid leukaemia [2A60]
|
[15] |
Daunorubicin |
DMQUSBT
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Daunorubicin. |
Acute myeloid leukaemia [2A60]
|
[15] |
Arn-509 |
DMT81LZ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Arn-509. |
Acute myeloid leukaemia [2A60]
|
[10] |
Oliceridine |
DM6MDCF
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Oliceridine. |
Acute pain [MG31]
|
[15] |
Terfenadine |
DM4KLPT
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Terfenadine. |
Allergic/hypersensitivity disorder [4A80-4A8Z]
|
[15] |
Galantamine |
DMEO794
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Galantamine. |
Alzheimer disease [8A20]
|
[15] |
Rivastigmine |
DMG629M
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Rivastigmine. |
Alzheimer disease [8A20]
|
[15] |
Donepezil |
DMIYG7Z
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Donepezil. |
Alzheimer disease [8A20]
|
[15] |
Metronidazole |
DMTIVEN
|
Minor |
Increased risk of prolong QT interval by the combination of Atomoxetine and Metronidazole. |
Amoebiasis [1A36]
|
[11] |
Ivabradine |
DM0L594
|
Major |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Ivabradine. |
Angina pectoris [BA40]
|
[10] |
Dronedarone |
DMA8FS5
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Dronedarone. |
Angina pectoris [BA40]
|
[15] |
Bedaquiline |
DM3906J
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Bedaquiline. |
Antimicrobial drug resistance [MG50-MG52]
|
[16] |
Hydroxyzine |
DMF8Y74
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Hydroxyzine. |
Anxiety disorder [6B00-6B0Z]
|
[15] |
Clobazam - Lundbeck |
DMW1OQ0
|
Moderate |
Decreased metabolism of Atomoxetine caused by Clobazam - Lundbeck mediated inhibition of CYP450 enzyme. |
Anxiety disorder [6B00-6B0Z]
|
[17] |
Cilostazol |
DMZMSCT
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Cilostazol. |
Arterial occlusive disease [BD40]
|
[15] |
Voriconazole |
DMAOL2S
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Voriconazole. |
Aspergillosis [1F20]
|
[15] |
Posaconazole |
DMUL5EW
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Posaconazole. |
Aspergillosis [1F20]
|
[15] |
Ofloxacin |
DM0VQN3
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ofloxacin. |
Bacterial infection [1A00-1C4Z]
|
[18] |
Ciprofloxacin XR |
DM2NLS9
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ciprofloxacin XR. |
Bacterial infection [1A00-1C4Z]
|
[15] |
Clarithromycin |
DM4M1SG
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Clarithromycin. |
Bacterial infection [1A00-1C4Z]
|
[15] |
Sulfamethoxazole |
DMB08GE
|
Minor |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sulfamethoxazole. |
Bacterial infection [1A00-1C4Z]
|
[15] |
Sparfloxacin |
DMB4HCT
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sparfloxacin. |
Bacterial infection [1A00-1C4Z]
|
[18] |
Linezolid |
DMGFPU2
|
Major |
Additive hypertensive effects by the combination of Atomoxetine and Linezolid. |
Bacterial infection [1A00-1C4Z]
|
[12] |
Levofloxacin |
DMS60RB
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Levofloxacin. |
Bacterial infection [1A00-1C4Z]
|
[18] |
Lomefloxacin |
DMVRH9C
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Lomefloxacin. |
Bacterial infection [1A00-1C4Z]
|
[15] |
Telithromycin |
DMZ4P3A
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Telithromycin. |
Bacterial infection [1A00-1C4Z]
|
[15] |
Retigabine |
DMGNYIH
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Retigabine. |
Behcet disease [4A62]
|
[15] |
Pexidartinib |
DMS2J0Z
|
Major |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Pexidartinib. |
Bone/articular cartilage neoplasm [2F7B]
|
[19] |
Loperamide |
DMOJZQ9
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Loperamide. |
Bowel habit change [ME05]
|
[20] |
Eribulin |
DM1DX4Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Eribulin. |
Breast cancer [2C60-2C6Y]
|
[15] |
Lapatinib |
DM3BH1Y
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Lapatinib. |
Breast cancer [2C60-2C6Y]
|
[15] |
Tamoxifen |
DMLB0EZ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Tamoxifen. |
Breast cancer [2C60-2C6Y]
|
[15] |
Toremifene |
DMQYUWG
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Toremifene. |
Breast cancer [2C60-2C6Y]
|
[15] |
Bosutinib |
DMTI8YE
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Bosutinib. |
Breast cancer [2C60-2C6Y]
|
[10] |
Grepafloxacin |
DMGLX0T
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Grepafloxacin. |
Bronchitis [CA20]
|
[18] |
Sotalol |
DML60TN
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sotalol. |
Cardiac arrhythmia [BC9Z]
|
[15] |
PF-04449913 |
DMSB068
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and PF-04449913. |
Chronic myelomonocytic leukaemia [2A40]
|
[21] |
Halothane |
DM80OZ5
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Halothane. |
Corneal disease [9A76-9A78]
|
[15] |
Propofol |
DMB4OLE
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Propofol. |
Corneal disease [9A76-9A78]
|
[22] |
Probucol |
DMVZQ2M
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Probucol. |
Coronary atherosclerosis [BA80]
|
[15] |
Methadone |
DMTW6IU
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Methadone. |
Cough [MD12]
|
[15] |
Clofazimine |
DMEBOFW
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Clofazimine. |
Crohn disease [DD70]
|
[23] |
Mifepristone |
DMGZQEF
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Mifepristone. |
Cushing syndrome [5A70]
|
[15] |
Pasireotide |
DMHM7JS
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Pasireotide. |
Cushing syndrome [5A70]
|
[15] |
Osilodrostat |
DMIJC9X
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Osilodrostat. |
Cushing syndrome [5A70]
|
[10] |
Sertraline |
DM0FB1J
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sertraline. |
Depression [6A70-6A7Z]
|
[15] |
Fluoxetine |
DM3PD2C
|
Major |
Decreased metabolism of Atomoxetine caused by Fluoxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[17] |
Paroxetine |
DM5PVQE
|
Major |
Decreased metabolism of Atomoxetine caused by Paroxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[17] |
Selegiline |
DM6034S
|
Major |
Additive hypertensive effects by the combination of Atomoxetine and Selegiline. |
Depression [6A70-6A7Z]
|
[12] |
Duloxetine |
DM9BI7M
|
Moderate |
Decreased metabolism of Atomoxetine caused by Duloxetine mediated inhibition of CYP450 enzyme. |
Depression [6A70-6A7Z]
|
[17] |
Isocarboxazid |
DMAF1NB
|
Major |
Additive hypertensive effects by the combination of Atomoxetine and Isocarboxazid. |
Depression [6A70-6A7Z]
|
[12] |
Escitalopram |
DMFK9HG
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Escitalopram. |
Depression [6A70-6A7Z]
|
[15] |
Tranylcypromine |
DMGB5RE
|
Major |
Additive hypertensive effects by the combination of Atomoxetine and Tranylcypromine. |
Depression [6A70-6A7Z]
|
[12] |
Phenelzine |
DMHIDUE
|
Major |
Increased risk of hyperpyrexia by the combination of Atomoxetine and Phenelzine. |
Depression [6A70-6A7Z]
|
[12] |
Clomipramine |
DMINRKW
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Clomipramine. |
Depression [6A70-6A7Z]
|
[15] |
Mirtazapine |
DML53ZJ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Mirtazapine. |
Depression [6A70-6A7Z]
|
[24] |
Esketamine |
DMVU687
|
Major |
Additive hypertensive effects by the combination of Atomoxetine and Esketamine. |
Depression [6A70-6A7Z]
|
[11] |
Tetrabenazine |
DMYWQ0O
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Tetrabenazine. |
Dissociative neurological symptom disorder [6B60]
|
[15] |
Deutetrabenazine |
DMUPFLI
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Deutetrabenazine. |
Dystonic disorder [8A02]
|
[25] |
Ingrezza |
DMVPLNC
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ingrezza. |
Dystonic disorder [8A02]
|
[26] |
Stiripentol |
DMMSDOY
|
Moderate |
Decreased metabolism of Atomoxetine caused by Stiripentol mediated inhibition of CYP450 enzyme. |
Epilepsy/seizure [8A61-8A6Z]
|
[17] |
Cannabidiol |
DM0659E
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Cannabidiol. |
Epileptic encephalopathy [8A62]
|
[10] |
Diphenhydramine |
DMKQTBA
|
Moderate |
Decreased metabolism of Atomoxetine caused by Diphenhydramine mediated inhibition of CYP450 enzyme. |
Episodic vestibular syndrome [AB31]
|
[17] |
Solifenacin |
DMG592Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Solifenacin. |
Functional bladder disorder [GC50]
|
[15] |
Mirabegron |
DMS1GYT
|
Moderate |
Decreased metabolism of Atomoxetine caused by Mirabegron mediated inhibition of CYP450 enzyme. |
Functional bladder disorder [GC50]
|
[17] |
Darifenacin |
DMWXLYZ
|
Moderate |
Decreased metabolism of Atomoxetine caused by Darifenacin mediated inhibition of CYP450 enzyme. |
Functional bladder disorder [GC50]
|
[17] |
Pentamidine |
DMHZJCG
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Pentamidine. |
Fungal infection [1F29-1F2F]
|
[15] |
Terbinafine |
DMI6HUW
|
Moderate |
Decreased metabolism of Atomoxetine caused by Terbinafine mediated inhibition of CYP450 enzyme. |
Fungal infection [1F29-1F2F]
|
[17] |
Ketoconazole |
DMPZI3Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ketoconazole. |
Fungal infection [1F29-1F2F]
|
[15] |
Cimetidine |
DMH61ZB
|
Moderate |
Decreased metabolism of Atomoxetine caused by Cimetidine mediated inhibition of CYP450 enzyme. |
Gastro-oesophageal reflux disease [DA22]
|
[17] |
Cisapride |
DMY7PED
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Cisapride. |
Gastro-oesophageal reflux disease [DA22]
|
[15] |
Sunitinib |
DMCBJSR
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sunitinib. |
Gastrointestinal stromal tumour [2B5B]
|
[15] |
Procarbazine |
DMIK367
|
Major |
Increased risk of hyperpyrexia by the combination of Atomoxetine and Procarbazine. |
Hodgkin lymphoma [2B30]
|
[12] |
Brentuximab vedotin |
DMWLC57
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Brentuximab vedotin. |
Hodgkin lymphoma [2B30]
|
[27] |
Delavirdine |
DM3NF5G
|
Moderate |
Decreased metabolism of Atomoxetine caused by Delavirdine mediated inhibition of CYP450 enzyme. |
Human immunodeficiency virus disease [1C60-1C62]
|
[17] |
Fostemsavir |
DM50ILT
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Fostemsavir. |
Human immunodeficiency virus disease [1C60-1C62]
|
[28] |
Cobicistat |
DM6L4H2
|
Moderate |
Decreased clearance of Atomoxetine due to the transporter inhibition by Cobicistat. |
Human immunodeficiency virus disease [1C60-1C62]
|
[29] |
Saquinavir |
DMG814N
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Saquinavir. |
Human immunodeficiency virus disease [1C60-1C62]
|
[30] |
Rilpivirine |
DMJ0QOW
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Rilpivirine. |
Human immunodeficiency virus disease [1C60-1C62]
|
[15] |
Ritonavir |
DMU764S
|
Moderate |
Decreased metabolism of Atomoxetine caused by Ritonavir mediated inhibition of CYP450 enzyme. |
Human immunodeficiency virus disease [1C60-1C62]
|
[17] |
Mipomersen |
DMGSRN1
|
Major |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Mipomersen. |
Hyper-lipoproteinaemia [5C80]
|
[31] |
Teriflunomide |
DMQ2FKJ
|
Major |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Teriflunomide. |
Hyper-lipoproteinaemia [5C80]
|
[15] |
BMS-201038 |
DMQTAGO
|
Major |
Increased risk of hepatotoxicity by the combination of Atomoxetine and BMS-201038. |
Hyper-lipoproteinaemia [5C80]
|
[32] |
Cinacalcet |
DMCX0K3
|
Major |
Decreased metabolism of Atomoxetine caused by Cinacalcet mediated inhibition of CYP450 enzyme. |
Hyper-parathyroidism [5A51]
|
[17] |
Givosiran |
DM5PFIJ
|
Moderate |
Decreased metabolism of Atomoxetine caused by Givosiran mediated inhibition of CYP450 enzyme. |
Inborn porphyrin/heme metabolism error [5C58]
|
[17] |
Polyethylene glycol |
DM4I1JP
|
Moderate |
Increased risk of lowers seizure threshold by the combination of Atomoxetine and Polyethylene glycol. |
Irritable bowel syndrome [DD91]
|
[15] |
Phenolphthalein |
DM5SICT
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Phenolphthalein. |
Irritable bowel syndrome [DD91]
|
[15] |
Methotrexate |
DM2TEOL
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Methotrexate. |
Leukaemia [2A60-2B33]
|
[10] |
Glycerol phenylbutyrate |
DMDGRQO
|
Moderate |
Decreased metabolism of Atomoxetine caused by Glycerol phenylbutyrate mediated inhibition of CYP450 enzyme. |
Liver disease [DB90-DB9Z]
|
[17] |
Crizotinib |
DM4F29C
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Crizotinib. |
Lung cancer [2C25]
|
[33] |
Ceritinib |
DMB920Z
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ceritinib. |
Lung cancer [2C25]
|
[15] |
Dacomitinib |
DMOH8VY
|
Major |
Decreased metabolism of Atomoxetine caused by Dacomitinib mediated inhibition of CYP450 enzyme. |
Lung cancer [2C25]
|
[17] |
Osimertinib |
DMRJLAT
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Osimertinib. |
Lung cancer [2C25]
|
[34] |
Selpercatinib |
DMZR15V
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Selpercatinib. |
Lung cancer [2C25]
|
[10] |
Lumefantrine |
DM29GAD
|
Moderate |
Decreased metabolism of Atomoxetine caused by Lumefantrine mediated inhibition of CYP450 enzyme. |
Malaria [1F40-1F45]
|
[11] |
Halofantrine |
DMOMK1V
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Halofantrine. |
Malaria [1F40-1F45]
|
[35] |
Chloroquine |
DMSI5CB
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Chloroquine. |
Malaria [1F40-1F45]
|
[36] |
Quinine |
DMSWYF5
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Quinine. |
Malaria [1F40-1F45]
|
[15] |
Primaquine |
DMWQ16I
|
Moderate |
Decreased metabolism of Atomoxetine caused by Primaquine mediated inhibition of CYP450 enzyme. |
Malaria [1F40-1F45]
|
[17] |
Calaspargase pegol |
DMQZBXI
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Calaspargase pegol. |
Malignant haematopoietic neoplasm [2B33]
|
[37] |
Idelalisib |
DM602WT
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Idelalisib. |
Mature B-cell leukaemia [2A82]
|
[38] |
Arsenic trioxide |
DM61TA4
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Arsenic trioxide. |
Mature B-cell lymphoma [2A85]
|
[39] |
Clofarabine |
DMCVJ86
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Clofarabine. |
Mature B-cell lymphoma [2A85]
|
[40] |
Vemurafenib |
DM62UG5
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Vemurafenib. |
Melanoma [2C30]
|
[15] |
Panobinostat |
DM58WKG
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Panobinostat. |
Multiple myeloma [2A83]
|
[41] |
Thalidomide |
DM70BU5
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Thalidomide. |
Multiple myeloma [2A83]
|
[11] |
Siponimod |
DM2R86O
|
Major |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Siponimod. |
Multiple sclerosis [8A40]
|
[11] |
Fingolimod |
DM5JVAN
|
Major |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Fingolimod. |
Multiple sclerosis [8A40]
|
[15] |
Ozanimod |
DMT6AM2
|
Major |
Increased risk of hyperpyrexia by the combination of Atomoxetine and Ozanimod. |
Multiple sclerosis [8A40]
|
[12] |
Romidepsin |
DMT5GNL
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Romidepsin. |
Mycosis fungoides [2B01]
|
[15] |
Fedratinib |
DM4ZBK6
|
Moderate |
Decreased metabolism of Atomoxetine caused by Fedratinib mediated inhibition of CYP450 enzyme. |
Myeloproliferative neoplasm [2A20]
|
[17] |
Imatinib |
DM7RJXL
|
Moderate |
Decreased metabolism of Atomoxetine caused by Imatinib mediated inhibition of CYP450 enzyme. |
Myeloproliferative neoplasm [2A20]
|
[17] |
Droperidol |
DM0DXA8
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Droperidol. |
Nausea/vomiting [MD90]
|
[15] |
Prochlorperazine |
DM53SRA
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Prochlorperazine. |
Nausea/vomiting [MD90]
|
[15] |
Promethazine |
DM6I5GR
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Promethazine. |
Nausea/vomiting [MD90]
|
[15] |
Rolapitant |
DM8XP26
|
Moderate |
Decreased metabolism of Atomoxetine caused by Rolapitant mediated inhibition of CYP450 enzyme. |
Nausea/vomiting [MD90]
|
[42] |
Palonosetron |
DMBHMOX
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Palonosetron. |
Nausea/vomiting [MD90]
|
[15] |
Granisetron |
DMIUW25
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Granisetron. |
Nausea/vomiting [MD90]
|
[15] |
Dolasetron |
DMMG26Z
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Dolasetron. |
Nausea/vomiting [MD90]
|
[15] |
Ondansetron |
DMOTQ1I
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ondansetron. |
Nausea/vomiting [MD90]
|
[15] |
Bupropion |
DM5PCS7
|
Moderate |
Decreased metabolism of Atomoxetine caused by Bupropion mediated inhibition of CYP450 enzyme. |
Nicotine use disorder [6C4A]
|
[17] |
Entrectinib |
DMMPTLH
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Entrectinib. |
Non-small cell lung cancer [2C25]
|
[11] |
Lorcaserin |
DMG6OYJ
|
Moderate |
Decreased metabolism of Atomoxetine caused by Lorcaserin mediated inhibition of CYP450 enzyme. |
Obesity [5B80-5B81]
|
[17] |
Dexfenfluramine |
DMJ7YDS
|
Moderate |
Decreased metabolism of Atomoxetine caused by Dexfenfluramine mediated inhibition of CYP450 enzyme. |
Obesity [5B80-5B81]
|
[17] |
Lofexidine |
DM1WXA6
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Lofexidine. |
Opioid use disorder [6C43]
|
[15] |
Rucaparib |
DM9PVX8
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Rucaparib. |
Ovarian cancer [2C73]
|
[15] |
Dextropropoxyphene |
DM23HCX
|
Moderate |
Decreased metabolism of Atomoxetine caused by Dextropropoxyphene mediated inhibition of CYP450 enzyme. |
Pain [MG30-MG3Z]
|
[17] |
Buprenorphine |
DMPRI8G
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Buprenorphine. |
Pain [MG30-MG3Z]
|
[15] |
Triclabendazole |
DMPWGBR
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Triclabendazole. |
Parasitic worm infestation [1F90]
|
[15] |
Safinamide |
DM0YWJC
|
Moderate |
Decreased metabolism of Atomoxetine caused by Safinamide mediated inhibition of non-CYP450 enzyme. |
Parkinsonism [8A00]
|
[43] |
Rasagiline |
DM3WKQ4
|
Moderate |
Additive hypertensive effects by the combination of Atomoxetine and Rasagiline. |
Parkinsonism [8A00]
|
[12] |
Pimavanserin |
DMR7IVC
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Pimavanserin. |
Parkinsonism [8A00]
|
[44] |
Apomorphine |
DMX38HQ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Apomorphine. |
Parkinsonism [8A00]
|
[15] |
Macimorelin |
DMQYJIR
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Macimorelin. |
Pituitary gland disorder [5A60-5A61]
|
[45] |
Lefamulin |
DME6G97
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Lefamulin. |
Pneumonia [CA40]
|
[46] |
Degarelix |
DM3O8QY
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Degarelix. |
Prostate cancer [2C82]
|
[10] |
ABIRATERONE |
DM8V75C
|
Moderate |
Decreased metabolism of Atomoxetine caused by ABIRATERONE mediated inhibition of CYP450 enzyme. |
Prostate cancer [2C82]
|
[17] |
Nilutamide |
DMFN07X
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Nilutamide. |
Prostate cancer [2C82]
|
[10] |
Enzalutamide |
DMGL19D
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Enzalutamide. |
Prostate cancer [2C82]
|
[10] |
Flutamide |
DMK0O7U
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Flutamide. |
Prostate cancer [2C82]
|
[10] |
Bicalutamide |
DMZMSPF
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Bicalutamide. |
Prostate cancer [2C82]
|
[10] |
Levomepromazine |
DMIKFEL
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Levomepromazine. |
Psychotic disorder [6A20-6A25]
|
[15] |
Fluphenazine |
DMIT8LX
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Fluphenazine. |
Psychotic disorder [6A20-6A25]
|
[15] |
Triflupromazine |
DMKFQJP
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Triflupromazine. |
Psychotic disorder [6A20-6A25]
|
[15] |
Sorafenib |
DMS8IFC
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Sorafenib. |
Renal cell carcinoma [2C90]
|
[15] |
Gatifloxacin |
DMSL679
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Gatifloxacin. |
Respiratory infection [CA07-CA4Z]
|
[47] |
Celecoxib |
DM6LOQU
|
Moderate |
Decreased metabolism of Atomoxetine caused by Celecoxib mediated inhibition of CYP450 enzyme. |
Rheumatoid arthritis [FA20]
|
[17] |
Leflunomide |
DMR8ONJ
|
Major |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Leflunomide. |
Rheumatoid arthritis [FA20]
|
[15] |
Oxamniquine |
DM2QDX1
|
Moderate |
Decreased metabolism of Atomoxetine caused by Oxamniquine mediated inhibition of CYP450 enzyme. |
Schistosomiasis [1F86]
|
[17] |
Mesoridazine |
DM2ZGAN
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Mesoridazine. |
Schizophrenia [6A20]
|
[15] |
Thioridazine |
DM35M8J
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Thioridazine. |
Schizophrenia [6A20]
|
[15] |
Aripiprazole |
DM3NUMH
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Aripiprazole. |
Schizophrenia [6A20]
|
[11] |
Iloperidone |
DM6AUFY
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Iloperidone. |
Schizophrenia [6A20]
|
[15] |
Paliperidone |
DM7NPJS
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Paliperidone. |
Schizophrenia [6A20]
|
[15] |
Haloperidol |
DM96SE0
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Haloperidol. |
Schizophrenia [6A20]
|
[15] |
Perphenazine |
DMA4MRX
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Perphenazine. |
Schizophrenia [6A20]
|
[15] |
Chlorpromazine |
DMBGZI3
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Chlorpromazine. |
Schizophrenia [6A20]
|
[15] |
Clozapine |
DMFC71L
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Clozapine. |
Schizophrenia [6A20]
|
[15] |
Trifluoperazine |
DMKBYWI
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Trifluoperazine. |
Schizophrenia [6A20]
|
[15] |
Risperidone |
DMN6DXL
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Risperidone. |
Schizophrenia [6A20]
|
[15] |
Amisulpride |
DMSJVAM
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Amisulpride. |
Schizophrenia [6A20]
|
[48] |
Asenapine |
DMSQZE2
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Asenapine. |
Schizophrenia [6A20]
|
[15] |
Vardenafil |
DMTBGW8
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Vardenafil. |
Sexual dysfunction [HA00-HA01]
|
[15] |
Gefitinib |
DM15F0X
|
Moderate |
Decreased metabolism of Atomoxetine caused by Gefitinib mediated inhibition of CYP450 enzyme. |
Solid tumour/cancer [2A00-2F9Z]
|
[17] |
Trabectedin |
DMG3Y89
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Trabectedin. |
Solid tumour/cancer [2A00-2F9Z]
|
[10] |
LEE011 |
DMMX75K
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and LEE011. |
Solid tumour/cancer [2A00-2F9Z]
|
[15] |
Epirubicin |
DMPDW6T
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Epirubicin. |
Solid tumour/cancer [2A00-2F9Z]
|
[11] |
Vandetanib |
DMRICNP
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Vandetanib. |
Solid tumour/cancer [2A00-2F9Z]
|
[15] |
Triptorelin |
DMTK4LS
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Triptorelin. |
Solid tumour/cancer [2A00-2F9Z]
|
[10] |
Doxorubicin |
DMVP5YE
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Doxorubicin. |
Solid tumour/cancer [2A00-2F9Z]
|
[15] |
Pitolisant |
DM8RFNJ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Pitolisant. |
Somnolence [MG42]
|
[15] |
Telavancin |
DM58VQX
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Telavancin. |
Staphylococcal/streptococcal disease [1B5Y]
|
[15] |
Naltrexone |
DMUL45H
|
Moderate |
Increased risk of hepatotoxicity by the combination of Atomoxetine and Naltrexone. |
Substance abuse [6C40]
|
[49] |
Ibutilide |
DMKXY2R
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Ibutilide. |
Supraventricular tachyarrhythmia [BC81]
|
[15] |
Adenosine |
DMM2NSK
|
Moderate |
Increased risk of ventricular arrhythmias by the combination of Atomoxetine and Adenosine. |
Supraventricular tachyarrhythmia [BC81]
|
[15] |
Lenvatinib |
DMB1IU4
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Lenvatinib. |
Thyroid cancer [2D10]
|
[15] |
Cabozantinib |
DMIYDT4
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Cabozantinib. |
Thyroid cancer [2D10]
|
[10] |
Papaverine |
DMCA9QP
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Papaverine. |
Tonus and reflex abnormality [MB47]
|
[50] |
Tizanidine |
DMR2IQ4
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Tizanidine. |
Tonus and reflex abnormality [MB47]
|
[15] |
Tacrolimus |
DMZ7XNQ
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Tacrolimus. |
Transplant rejection [NE84]
|
[15] |
Astemizole |
DM2HN6Q
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Astemizole. |
Vasomotor/allergic rhinitis [CA08]
|
[15] |
Trimeprazine |
DMEMV9D
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Trimeprazine. |
Vasomotor/allergic rhinitis [CA08]
|
[51] |
Procainamide |
DMNMXR8
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Procainamide. |
Ventricular tachyarrhythmia [BC71]
|
[15] |
Propafenone |
DMPIBJK
|
Moderate |
Increased risk of prolong QT interval by the combination of Atomoxetine and Propafenone. |
Ventricular tachyarrhythmia [BC71]
|
[15] |
Amiodarone |
DMUTEX3
|
Major |
Increased risk of prolong QT interval by the combination of Atomoxetine and Amiodarone. |
Ventricular tachyarrhythmia [BC71]
|
[15] |
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